Analytical solutions for
Metal Organic Framework materials
Grow your knowledge. Build robust structures.

2

3

The world of Metal Organic Frameworks

Where materials analysis comes in

What are MOFs?

Crystal structures: Key to collection

Metal Organic Frameworks (MOFs)
are hybrid crystals created by selfassembling organic and inorganic
molecules. MOFs contain nano-scaleinterconnected voids – giving them
unrivaled potential for trapping, storing
and catalyzing ions and molecules.
Adjusting their local environment (such as
the electric field, temperature, pressureor chemistry) can enable the adsorption
or release of many molecules or ions.

OH

✓
✓

4.4 eq. (IPr)2NEt
rt. 5 minOH

High crystallinity
Controllable pKb✓✓

That means you need a deep understanding of the crystalline lattice
structure and how it interacts with other molecular and ionic species.
And for this, you need a strong understanding of the structuralchanges that result from variations in the host environment.

No organic solvent
High surface areas

Organic molecules can form large, interpenetrating lattices
made of a framework of large pores. But, on their own, they
are relatively fragile. Reacting these molecules with metal
ions creates MOFs: strong covalent structures that are
more durable than organic crystals. These materials can besynthesized on surfaces as thin films, obtained from solution
as dry powders, or used as nanoparticles in liquids.

Thanks to their collection abilities,
MOFs are ideal for several applications,
including gas storage and separation,liquid separation and purification,
electrochemical energy storage, catalysis,or drug delivery. They are also usefulfor gas sensor devices that measure
and respond to this capture process.

Particle morphology for maximum performance
How do you maximize the performance of a MOF powder to ensure robust, consistently
processable products? By optimizing the physical properties of the particles!
Specifically, the particles’ total surface area determines how effectively gas or
liquid can flow through and how quickly the MOF can trap or release molecules orions. So, for the best MOF product, particles must remain a constant size, intact
and not agglomerated. The powder’s flow and packing also have to be controlled.
And for this, you need to understand the size and shape of your MOF particles.

Sensors

How can we help?

Nanoparticles in liquid:hydrodynamic performance
Separation

Our solutions deliver in-depth
materials insights, from nanoscale tomacroscale. Whatever the project,product or process, we’ll help
you to optimize your material.
On the following pages, we hope
you’ll find solutions that could
benefit you. If you want to dive
deeper into their specific benefits,
don’t hesitate to get in touch!

3.0 eq. Mg(NO3)2 6H2O

The hybrid structure of MOFs

What are theyused for?

At Malvern Panalytical, ourglobal network of over 170
scientists is continuously working
to support customers withadvanced materials like MOFs.

·

CO2H
HO2C

What exactly makes MOFs so good at collection? Their complex crystal structures!
These structures contain voids, and the interconnectivity between these voids
makes MOFs nanoporous. The exact structure depends on the MOF’s constituent
molecules and how it is synthesized. By tailoring this, you can optimize size,
connectivity and binding affinity to attract specific molecules or ions.

Gas storage

When formulated as nanoparticles in suspension, MOFs can carry awhole range of active and targeted pharmaceutical drugs. That’s because
surface modification enables these nanoparticles to access cells.
Understanding the hydrodynamic behavior of these surface-activated
MOF nanoparticles is essential for all stages of the process.

MOF
Drug storage

One way to measure how effectively a MOF can harvest or release ions is to measure
the elemental concentration of ions in residual concentrations in its carrier liquid.

Catalysis“These are really exciting times – I have never seen such capabilities in a material.
The selectivity, the robustness, the scale of response: it’s mind-blowing.”
Purification

Dr Ana Morfesis –Principal Scientist, Malvern Panalytical45

Crystal structure

Binding affinity

Why is crystal structure
analysis important?

Why analyze crystal structureduring occupancy cycling?

To understand your MOF structures in detail andcheck that your target MOF has been synthesized
correctly, you need to be able to identify any changes
to the crystal structure – quickly and easily.

By studying the MOF’s crystal structure during
occupancy cycling, you can understand how morphology,
packing, and use environment affect its performance– and design your use environment accordingly.

Binding affinity at different sites
What are the benefits of understanding binding affinity
at specific binding sites in your MOF pores? Better
MOF structures for specific adsorption species, andlong-term robustness in various use environments.

Integrated non-ambient measurements

A complete thermodynamic profile

X-ray powder diffraction is a well-established
way to measure and verify crystal structure. Our
Empyrean and Aeris X-ray diffractometers canprovide the highest-quality powder diffraction
data. Count on their resolution and sensitivity to
pin down even the finest structural details.

Our X-ray diffractometers let you study the crystal
structure changes in your MOFs – whatever theoperating conditions. Choose from several integrated
non-ambient chambers and reaction cells, and rapidly
identify points of change with HighScore software,incorporating 2D and 3D graphics and cluster analysis.

By measuring heat transfer during binding, you
can accurately determine binding constants (KD),reaction stoichiometry (N), enthalpy (∆H), andentropy (ΔS). Our ultrasensitive Microcal PEAQITC microcalorimeter makes measuring these
thermodynamic changes easy – giving you a complete
thermodynamic profile of adsorption and desorption.

Empyrean: Structural solutions

Aeris: Rapid fingerprinting

Empyrean: Capture and release of water

Basics of ITC experiment

The excellent fit of this high resolution and lowbackground transmission data demonstrates that
great data quality leads to an accurately determined
structural model. The result even locates thehydrogen atom of the MOF’s phenolic group.

The powder diffraction scan below was obtainedin a 5-minute scan on the Aeris diffractometer.
It shows two MOF samples with nominally thesame constituents, synthesized by two different
routes. The green arrows show extra reflections,indicating that Sample 2 is not pure enough.

Because the MOF CAU-10-H can store water molecules(H2O), it has potential applications in water harvesting.

Universal technique based on heat detection

These isoline plots show variable in situ relative
humidity data collected at two temperatures,
demonstrating the effect of temperature on theadsorption and desorption of water within the sample.
34
32
Humidity [%]MOF CAU-10H synthesis 1
MOF CAU-10H synthesis 2

28
24
20

25°C

18

2000

9

9.5

10

10.5

1500

1000

11
11.5
12
Position [°2θ] (Copper (Cu))

12.5

13

13.5

7

8

9

10

11

12

13

14

15

16

17

18
2Theta (°)

∆H

-4

KD

N
0

0.5

1.0 1.5 2.0

Integration of heats are used to extract affinity(KD), stoichiometry (N) and binding enthalpy(ΔH) using appropriate binding model

The MOF NU-1000 can effectively extract uremic toxins1– both when free in aqueous media and when bound tohuman serum albumin (HSA). These authors measured
the interactions of the toxins at different binding sites
in the MOF using ITC, revealing both entropically andenthalpically driven adsorption at two different pore sites.

32

0

-2

ITC: Example report

34

500

0

Molar ratio

26
22

2500

Humidity [%]Intensity (counts)

Time >

30

5 Minute scans

kcal mol-1of injectant

X-ray diffraction: A certified solution

Structural variations can happen when raw materials
are changed or if the material synthesis routeis different. Long-term cycling or environmental
conditions may also cause degradation in thelattice. Measurements can show whether your
MOF’s pores are empty or partially filled.

µcal S-1

What causes structural changes?

30
28
26
24
22
20

50°C

18
9

9.5

10

10.5

11
11.5
12
Position [°2θ] (Copper (Cu))
1

12.5

13

13.5


Cell
Reports Physical Science, Volume 1, Issue 1, 22 January 2020, 100006: https://doi.org/10.1016/j.xcrp.2019.100006

6

7Particle size

Particle shapeMore optimized product formulation

The right size for the right application

MOFs are often produced in powder form, as they
precipitate from a reaction in a solvent. The physical form
must remain reproducible and stable. This means thepowder particles must stay a constant size, intact, andnot agglomerated throughout their use. Fast particle size
distribution measurements can help you quickly understandthese process parameters to deliver optimum product size.

Each MOF has an optimum particle size – and size
distribution – for its intended application:• Bulk MOF powder particles designed to interact
with gases can be 1 to 100s of microns large• For batteries, smaller particles (20 nm to 1 micron)
reduce ionic diffusion lengths. They must be
distributed evenly in thin multi-layered structures.
• For drug delivery in biological systems,
MOF nanocrystals (<100nm) in suspension
are used. They can be small enough evento penetrate the blood brain barrier.

Partical Size
Range

Smarter particle sizing:
What’s the best option?
But which particle sizing method
is right for you? Each instrumentin the table has different benefits– and they can also measureadditional attributes. Ultimately,
your research, development,or production requirements will
determine the best instrument andmethod. And with this many options,
we’re sure to find your match!

Dynamic Light
Scattering<1nm to >1μm
Nanoparticle
Tracking Analysis<100nm to >1mm

Tracking particle
degradation

In powder, particle shape affects
packing, flow, and the chanceof agglomeration. In dispersion,
particle shape can influence thestability of a formulation. Imaging
is a great way to measure particle
size and shape to understandor monitor performance.

Repeated cycling, along with the
influx and outflux of ions andmolecules, can cause particle
degradation or incomplete emptyingof the MOF, leaving a residual
occupancy that increases over time.
You can track this particle
degradation using imaging with
Raman spectroscopy chemical
analysis, giving vital clues about
your products’ shelf-life. Raman
can help you see what proportionof your particles have an adequateloading of, for instance, active
pharmaceutical ingredient (API).

0.1nm 1nm 10nm 100nm 1μm 10μm 100μm 1mm 10mm

Zetasizer
NanoSight

Laser
Diffraction<100nm to >3.5mm

Mastersizer

Automated
Imaging<1μm to >1.3mm
SAXS<1nm to >1μm

The importance ofparticle shape

Morphology
Empyrean

Automated imaging for advanced
particle characterization

Single particle

Agglomerate

RegularElongated

Rough

Smooth

Dark

Light

Automated imaging gives you both instant and long-term information on
the physical robustness and performance of your individual MOF particles.
With Morphologi 4, you can scan 10,000 – 500,000 particles and get a fullset of size and shape results for each particle. All in just 30 minutes!
What’s more, you can opt for your results to show only what’s most
relevant to you. And, with Morphologi 4-ID, you can return to any individual
particle for more detailed analysis, including Raman chemical profiling.

Mastersizer 3000: Particle size distribution

Mastersizer 3000: Particle agglomeration

Morphologi 4-ID: Raman spectroscopy

This figure shows the results of a laser diffraction
measurement using the Mastersizer 3000. The sample
data from 5 measurements reveal a narrow andreproducible particle size distribution peaking at 48μm.

This figure shows the results of a laser diffraction
measurement using the Mastersizer 3000. The
sample was measured in a dispersion revealinga broad distribution of fine and agglomerated
particles. The mean particle size reduces after
sonication, showing a reduction in agglomeration.

This figure shows a published result of some imaging
and Raman results demonstrating the degradation of
biocompatible MOF crystals in a biological medium.
The MOF crystals are being studied for their potential
in drug delivery applications. It is important that theparticles are dissolved in the body during drug release.
The authors studied new particles before degradationand then particles in biological medium (I) which, overtime, developed denuded regions around the edges(II). Raman spectroscopy revealed that the degradedregion was losing the organic ligand in the MOF2.
Further studies showed the eventual collapse of the
inorganic matrix as it dissolved in the biological medium.

D

Intensity

A
B

F

C
E

I

20 µm

II

MicroMOF
before degradation
100

400

700

20 µm
MicroMOF
after degradation

1000 1300 1600 1900

Raman shift (cm-1)
Image courtesy of X. Li and R. Gref, Université Paris-Saclay
2

Int. J. Pharm. 2017531(2): 424-432 https://doi.org/10.1016/j.ijpharm.2017.05.056

8

9

Nanoparticles in liquids

Nanoparticles in liquids

Why study nanoparticle stability?

Know your purity levels

Assessing ionic uptake and expulsion

Understanding the size and surface charge of MOF
nanoparticles in solution is critical to controlling
mobility and aggregation. Controlling particle size
in bioactive drugs is particularly important, as it
ensures that drug carriers can pass through biologicalbarriers and reach their intended destination.

Knowing the purity of your starting materials andintermediate precursors can be important in developing
your MOF synthesis and product processing.

You can measure how effectively your MOF particles
trap and release ions from solutions by measuring
ion concentrations – for example in filtered solutions,or (for batteries) in separators and electrolytes.

Monitoring impurities from
catalyst residuals

Elemental insights with
X-ray fluorescence

MOFs can be used as catalysts – for example, in the
production of carbon nanotubes.7 Catalyst residues
can cause unwanted impurities in nanomaterials,
affecting their properties and the final application.
XRF analysis can monitor these impurities.

Our X-ray fluorescence (XRF) instruments can help
determine your sample’s chemical composition –whether it’s solid, liquid, slurry, or loose powder. You
can also use our sample preparation equipment tomake peroxide solutions for ICP elemental analysis.

+++ + ++
+ +
- ++
+ +
+
+
+
+
+ ++
+
++ + + +++ +-Light scattering for in-depth
nanoparticle analysis

Modifying nanoparticle surfaces
Modifying the surface of MOF nanoparticles can help
optimize their behavior in liquids. In drug delivery,
for instance, the right surface enables access tocells. In water treatment, adjusting surface charge
can optimize the absorption of toxic pollutants3.

You can measure the size of nanoparticles in liquids
using Dynamic Light Scattering (DLS) on the Zetasizer
Advance. Or, to analyze particle drift for Zeta potential,
use Electrophoretic Light Scattering (ELS). And
Nanosight NS300 complements these measurements,
providing real-time imaging of particle movement, withtracking analysis for both sizing and concentration.

Example applications• For battery and electronic applications, MOF
particles must remain structurally stable underenvironmental changes. Zeta potential is a usefulmeasure of this stability4,5 when pH values change.
• MOFs can be used as catalysts to degrade
pharmaceuticals and cosmetics and prevent
them from contaminating waste. Dynamic
light scattering can qualify and control thesynthesis of suitable catalytic MOF particles6.

XRF spectrum of carbon nanotube sample
showing residual impurities

3

Journal of Environmental Sciences, Volume 80, June 2019, Pages 197-207: https://doi.org/10.1016/j.jes.2018.12.013

4Front. Chem, 04 August 2020: https://doi.org/10.3389/fchem.2020.00617

5

Nano Energy, Volume 65, November 2019, 104032: https://doi.org/10.1016/j.nanoen.2019.104032

6
Chemosphere,
Volume 196, April 2018, Pages 105-114: hhttps://doi.org/10.1016/j.chemosphere.2017.12.164

7

Reference: Inorg. Chem. 2019, 58, 5, 3227–3236 : https://pubs.acs.org/doi/10.1021/acs.inorgchem.8b03318

10

11

Crystal structure
Research
You need a MOF crystal that fulfils yourapplication requirements – without fail:• A robust crystal structure that adsorbs
the correct molecules or ions

Our solutions
Crystal structure
Let our Empyrean and Aeris X-ray diffractometers
take your crystal structure analysis to the next level.

• The right adsorption capacity – obtained
through the right physical morphology• Understanding of the process, with matching
fluid flow and composition (liquid or gas)
• Characterization and fine-tuning ofadsorption and release parameters

Development
You need an upscaled process that achieves:• The correct crystal structure• The required physical morphology• A robustly contained material• Reproducible adsorption and release parameters

Binding affinity
The ultrasensitive microcalorimetry of our Microcal
PEAQ-ITC gives you direct measurementsof binding affinity (KD), stoichiometry (n),enthalpy (ΔH), and entropy (ΔS).

Particle size and shape
Use our Mastersizer 3000 for particle size distribution
with laser diffraction, Morphologi 4 for particle sizeand shape analysis, and Morphologi 4-ID to analyze
particulate chemistry with automated imaging andmorphologically directed Raman spectroscopy (MDRS).

Elemental analysis
Production

The X-ray fluorescence (XRF) spectroscopy of
Epsilon and Zetium makes elemental analysis of
MOFs and their fluid environments easier than ever.

And you need product quality, every time:• Testing for chemical impurities• Fast quality assurance of crystal structure• Fast quality assurance of sample morphology• Effective in-line measurements• Automated measurement and analysis

Nanoparticles
Need to analyze MOF nanoparticles insuspension? Zetasizer Advance has you
covered with dynamic light scattering (DLS) andelectrophoretic light scattering (ELS). For particle
size and concentration analysis, try NanoSight
NS300 using Nano Tracking Analysis (NTA).

Let us help you

12

13

These are just some of the measurements
and analyses you can perform with
Empyrean – get in touch to discover
the full range of possibilities.

Built on over 50 yearsof experience, Aeris isdesigned for precisionand longevity. Count on
its top-quality data andreproducibility to keep
your products on track.

Empyrean

Aeris

Empyrean is for you if you want:

Aeris is for you if you want:• The world’s most accurate high-resolution
goniometer for state-of-the-art diffraction
and scattering experiments.

• The widest range of sample holders and sample
stages for manual and automated sample exchange.

• An easy-to-operate instrument combining one-stepsample loading with simple push-button operation.

• A full choice of Universal PreFIX optics andstages for fast, accurate component exchange.

• Fully integrated non-ambient sample chambers.
• Bespoke design and integration for sample
mounting and in situ experiments.

• The quality of a floor-standing
diffractometer in compact form.

• iCore and dCore optics for multiple
measurements with batch automation.
• 0D, 1D and 2D solid-state detectors – fully
integrated, low-noise, and high-resolution.
• Advanced configurations for specializedmeasurements (capillary transmission,
SAXS, GISAXS, HR-XRD, PDF and CT).

• HighScore and HighScore Plus: user‑friendly
software for phase analysis, Rietveld
refinement, fingerprinting, cluster analysis,
non-ambient studies – and more!
• Fully automated analysis routines – forindividual measurements or large data sets.

And for MOFS take a look at:

Low-background,high-resolution iCoreand dCore detectors
reveal even the smallest
peaks in automatedmeasurements.

Your choice of optics
and configurations tominimize texture – andthe best low-angle peak
shapes for Rietveld fitting.

• Unrivaled low detection limits for small powder
diffraction peaks and material variations.
• High-resolution 1D and 2D solid-state detectors.
• Powder diffraction measurements in reflection,transmission and grazing incidence.
• Safe, precise external sample loading anytime.
No need to disturb ongoing measurements!

• The widest range of sample holders andsample stages – with various options formanual and automated sample exchange.
• An uncoupled theta-2theta goniometer to keep
your samples safe and your instrument clean.
• Rapid instant results with RoboRiet automatedanalysis. Wave goodbye to waiting times!
• Integrated non-ambient temperature chamber.
• Full integration into an automatedlab or processing plant.

And for MOFS take a look at:

Integrated non-ambient
stages for controlled,
synchronized measurements– every time.

All the sample holder
types you could want
– and up to 48 samples
loaded for automatedbatch analysis.

With push-button
powder diffraction,
you don’t need to be
an expert to manage
quality control.

Automation streamlines
your processes andcuts your production
overheads. No more
unnecessary expenses!

Grazing-incidence
diffraction improvesdetection limits:
Get ready to analyze eventhinner films and coatings!

2D capability lets you
check your crystallites’
processing quality – large
or small, random or
preferred orientation.

14

15

A rugged, easy-to-use design withintelligent software and high sensitivity
gives you all the thermodynamic
parameters you’ll need.

The Mastersizer 3000’s versatility means
you can create the ideal setup for
consistent results – again and again.

MicroCal PEAQ-ITC

Mastersizer 3000

MicroCal PEAQ-ITC is for you if you want:

Mastersizer 3000 is for you if you want:• An easy-to-operate, ergonomically designed
instrument. Say hello to a smoother experience!

• Hastelloy® sample cell: suitable for a wide rangeof compounds.

• Robust, rapid particle size measurements spanning
10nm – 3500μm in a single optical path.

• Live feedback on dispersion and sonication, for
optimum particle conditions.

• High-quality, reproducible results with minimal
experimental artifacts.

• Instrument control software with guided workflows,
step-by-step tutorials, and maintenance alerts.

• Intuitive software with built-in expertise – for faster
analysis than ever!

• A full real-time view of instrument controls, live data,
and trends.

• High signal-to-noise – for greater confidence inyour data’s quality and relevance.

• Analysis software with experimental design
simulation, batch evaluation of large data sets,
automated assessment of data quality, and a
streamlined user interface.

• Measurement of dry powders, suspensions andemulsions, with multiple plug-and-play dispersion
units.

• Automatic cleaning and easy switching from liquid
to dry dispersions. No additional stress necessary!

• An integrated washing module with quick disconnect
fittings and liquid sensors.
• Full cleaning of both sample cell and titration syringe– even at elevated temperatures.

• Presentation-quality graphics: sharing your findings
just got easier.

• Easy, reproducible operating procedures via the
Measurement Manager interface.

• Flexible dry dispersion – for robust or fragile
materials, and whatever the sample volume.
• Fully editable reporting – so the benefits continue
after analysis.

• Robust injection syringe filling and cleaning system.

And for MOFS take a look at:

Robust injection syringe
filling and cleaningsystem.

Unique pipette andtitration syringe.

And for MOFS take a look at:

Integrated washing modulewith liquid sensors.

MicroCal PEAQ-ITC
Automated.

Aero funnel sample
feeder for Aero dry
powder dispersion units.
Enjoy rapid quality control
for your bulk powder
samples!

Hydro EV – a unique dipin wet sample dispersion
unit, used with standard
laboratory glassware for awide range of dispersantvolumes.

Hydro Insight - real-time
images of liquid particle
dispersions and individual
particles, with quantitative
data on particle shape.

Ask us about in-line andat-line particle sizers andbespoke auto- sampling
solutions!

16

17

Automated particle imaging lets you discover
the physical properties of each one ofyour MOF particles – now and over time.

With the Zetasizer Advance’s wealth ofmeasurement options, you know you’re getting
the best results for your unique samples.

Morphologi 4-ID

Zetasizer AdvanceMorphologi 4 and Morphologi 4-ID are for you if you want:Zetasizer Advance is for you if you want:• To scan 10,000 – 500,000 particles from
0.5 to 1300μm – with full results of up
to 20 parameters in 30 minutes.

• Automated ‘sharp-edge’ analysis to detect
low-contrast particles.

• Results that present only what’s relevant to you.

• An integrated dry powder dispersion unit for
reproducible sample dispersion.

• To analyze individual particles in more detail with
Raman chemical profiling.

• Advanced data exploration tools – for maximum
sample knowledge.

• A wider range of sample concentration and particle
sizes – thanks to Non-Invasive Back Scatter (NIBS)
technology.
• The highest-resolution sizing data from combined
Multi-Angle Dynamic Light Scattering (MADLS®)
technology.

• A high-resolution microscope for the highest-quality
particle images.

• Accurate size measurements of 1nm-10μm particles.

And for MOFS take a look at:

And for MOFS take a look at:• A confident understanding of your sample’s stability
and aggregation potential.

• Constant current mode – say goodbye to data errors
from electrode polarization.
• Repeatability with minimal sample preparation,
thanks to the Adaptive Correlation algorithm.
• A sample-centric workflow to automate even themost complex analyses.
• Instant automatic feedback and actionable advice.

SAMPLE
PREPARATIONIMAGECAPTUREIMAGE
PROCESSINGMDRSRESULT
GENERATION

Integrated dry powderdispersion unit, making
reproducible sample
preparation easy.

Wet dispersion cell – soyou can analyze 2-6
mL of your sample.

Imaging workflow and
SOP control – from sample
dispersion to data analysis.

A great choice of sample
holders, including
slide holders for
traditional microscopy.

The ZSU1002 cell forsample volumes as low
as 3μL and particles
up to 10μm. Say hello
to a wider dynamic
concentration range!

Our completely
disposable cell – no morecross- contamination
between measurements!

The MPT-3 titrator
automates your titrations
for Zeta or size vs. pH.

Our dip cell lets you
measure zeta potential inboth aqueous and nonaqueous dispersants.

18

19

With Nanosight NS300, you canunderstand your nanoparticle
suspensions in more depth than ever.

Whatever your requirements,
Epsilon has something foryou – from the simplest
monitoring to the mostdemanding measurements.

NanoSight

Epsilon range

NanoSight NS300 is for you if you want:

Epsilon 1 or Epsilon 4 is for you if you want:• Particle size images and measurements from 10-1μm,
at up to 1 x 109 particles/mL.

• Non-destructive detection of elements from
C-Am, with detection limits from 1 ppm – 100%.

• Optional standardless analysis
with Omnian software.

• Particle-by-particle, high-resolution particle size
data, plus concentration measurements for colloidal
suspensions or nanoparticle solutions.

• A unique dynamic range and high elemental
resolution – whatever the sample matrix.

• A pass-fail fingerprint programfor quick quality control.

• Easy management of powders, solids,
films, filters, and solutions.

• A full workflow package: from auto-sampling andsample preparation to measurement and analysis.

• Fast, accurate analysis, at-line or in-line.

• Automation options.

• Quantification of primary sample components,
aggregates, and fluorescently tagged particles.
• High-resolution information on monomodal andpolydisperse systems – across all kinds of materials.

• Advanced data treatment algorithms.

And for MOFS take a look at:

Comprehensive realtime data viewing andanalysis.

NanoSight syringe pumplets new particles flow
continuously into thesample chamber.

And for MOFS take a look at:

NanoSight Sample
Assistant: enjoy precise,
reproducible, automatedsample loading from a 96well plate.

Low-volume flow cell –delivering data from as
little as 250μL.

Epsilon 4’s 10-position
carousel, 50-100
position sample
changer, and unlimited
belt automation. The
possibilities are endless!

Xflow automatedelemental analysis ofliquids – whether it’s online or at-line.

Fusion sample preparation
for XRF and ICP analysis.

Choose from a wide
range of our certified
reference materials(CRMs). We’ll even create
bespoke CRMs for yourunique applications.

Service & Support

When you make the invisible visible,
the impossible is possible.

Malvern Panalytical provides the global training, service
and support you need to continuously drive youranalytical processes at the highest level. We help you
increase the return on your investment with us, andensure that as your laboratory and analytical needs
grow, we are there to support you.

Our analytical systems and services help ourcustomers to create a better world. Throughchemical, physical and structural analysis of materials,
they improve everything from the energies thatpower us and the materials we build with, to the
medicines that cure us and the foods we enjoy.
We partner with many of the world’s biggest companies,
universities and research organizations. They value us
not only for the power of our solutions, but also for thedepth of our expertise, collaboration and integrity.
With over 2200 employees, we serve the world,
and we are part of Spectris plc, the worldleading precision measurements group.

Our worldwide team of specialists adds value to yourbusiness processes by ensuring applications expertise,
rapid response and maximum instrument uptime.
• Local and remote support• Full and flexible range of support agreements• Compliance and validation support• Onsite or classroom-based training courses• e-Learning training courses and web seminars• Sample and application consultancy

Malvern Panalytical. We’re BIG on small™

Malvern Panalyticalwww.malvernpanalytical.com

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Worcestershire, WR14 1XZ,
United Kingdom

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