National Center for
Global Health andMedicine

https://www.ncgm.go.jp/en/index.html

Think for World, Think for Human
Over many years, the Japanese government has provided proactive aid to developing countries under the philosophy
Health and Welfare (the present Ministry of Health, Labour and Welfare) stated that it was necessary to establish a

Index
03

Mission & Philosophy

15

Disease Control and Prevention Center (DCC)04

Message from the President

16

AMR Clinical Reference Center05

History and Future of NCGM

17

Medical Examination Center

31

07

Response to Health Crises

18

Stroke Center / Comprehensive Cancer Center

33

Institute for Global Health Policy Research (iGHP)

09

Organization Chart

19

Nursing Department

34

Human Resource Strategy Center for Global Health /10

Facilities

20

International Health Care Center / Biobank

conduct surveys and research regarding international cooperation in health and medicine for such diseases, dispatch

11

Center Hospital

21

Center for Clinical Sciences

35

National College of Nursing, Japan

experts in health and medicine, train specialists, and undertake other necessary activities in a comprehensive manner;

13

Department of Emergency Medicine

23

Kohnodai Hospital

37

Accessand Critical Care27

Research Institute

AIDS Clinical Center (ACC)

29

Diabetes Research Center

center for international cooperation in health and medicine in order to further enhance and strengthen cooperation inthese fields, under the belief that it is one of the most socially effective types of humanitarian assistance and directly
connected to the basic needs of human living in developing countries. Following many efforts, the International Medical
Center of Japan was launched in October 1993. In April 2015, the center was designated as one of the national centers foradvanced, specialized medical research aiming to maximize the achievements of R&D. All our activities are undertaken
under these shared goals: to examine and treat infectious and other diseases that require an international response; toand, above all, to be the base for Japan’s international contributions in health and medicine as the National Center
for Advanced and Specialized Medical Care. These are the permanent goals of NCGM in the past, present and future.

1

14

30

Research Center for Hepatitis and Immunology /Medical Genomics Center
Bureau of International Health Cooperation

INTRODUCTIONINTRODUCTION

of harmonized international development and humanitarian efforts. In its report published in 1979, the Ministry of

Global Health & Medicine

2

MISSION & PHILOS OPHY
The 3 Gs of contribution by NCGM to the world

G

The world was afflicted by Spanish flu in 1918 and COVID- 19 in2020 . NCGM continues to undertake proactive medical research andpublic health activities considering people's health not only in Japanbut also across the world. To achieve international harmony throughcontributions to global health. This is one of our goals.

G

As a general hospital that represents Japan, we are able to handle any
disease and condition. This is our pride and responsibility. Responding
to the needs of the time and envisioning the future, NCGM supports
healthcare in an increasingly aging Japan, treating AIDS, hepatitis andother infectious and immune diseases, cancer, and strokes.

G

The most advanced medical services in Japan are available at our hospitals. We areaiming to function as a research hub for high-precision genome medicine, AI-based
and other types of personalized medicine, and highly advanced medicine. This hub
will be used to develop new drugs for AIDS and hepatitis, to transplant pancreatic
islet cells for type 1 diabetes, to develop diagnostic and therapeutic methods formalaria and other tropical diseases, and other R&D activities.

lobal health contribution

rand general hospital

ateway to the Precision Medicine

Philosophy of the National Center for Global Health and Medicine (NCGM)MISSION & PHILOSOPHY❶ We at NCGM seek to provide healthcare,❸W e broadly publish achievements in healthcare, research,❷ We educate and train talented healthcare professionals❹W e function as a bridge with the global health community

research and education of the highest class in the world.
who will support the future of medicine.

education and international cooperation to the general public.
through health cooperation.

Philosophy and basic policy of the Center Hospital and the Kohnodai Hospital
The Center Hospital and the Kohnodai Hospital of NCGM provide the best general healthcare services toovercome diseases and improve health with the aim of contributing to society.
❶ Integrating treatment and research to provide healthcare❹P roviding safe and effective healthcare and sharing its effects❷ Providing healthcare services through collaboration among❺F ocusing efforts on educating and developing high-quality

services with consideration for patients.

highly-advanced pioneering disciplines.

with society at large.

medical professionals with extensive expertise.

❸P romoting team-based treatment approach based on mutual trust.

Philosophy of the Research Institute
The NCGM Research Institute actively promotes pioneering basic research, translational research, andclinical research, contributing to society by overcoming diseases and promoting health.
Mission of the Bureau of International Health Cooperation
Aiming to realize the world where all the people can equally lead healthy lives, the Bureau of International Health
Cooperation provides support around the world, including low and middle income countries, to improve healthcareusing our expertise and contributes to healthier lives of Japanese people by bringing these experiences back toJapan.
Rights of patients
As a designated National Center for Advanced and Specialized Medical Care and an advanced treatment hospital,
the Hospitals of NCGM respect the personality of each patient, support self-determination by the patient, andprovide optimal healthcare based on mutual trust.

3

National Center for Global Health and Medicine

Norihiro Kokudo, President
The National Center for Global Health and Medicine (NCGM)
has long history starting from 1868. At present, NCGM isa National Center functioning as a hospital and takes on adiversity of roles. These include undertaking basic medical
research directly connected to clinical practice, promotinginternational health cooperation, and developing humanresources at the National College of Nursing, Japan, and otherinstitutions. Its comprehensive, broad range of activities canbe expressed as the 3 Gs. The first G stands for "Global healthcontribution." Starting from healthcare cooperation in Bolivia
in the 1980s, NCGM has dispatched more than 4,500 staff
members to 134 countries in total. It has provided assistancein overall healthcare policies in Asia, Africa and othercountries, including health insurance systems, maternity
healthcare, and nurse certification systems.
The second G stands for "Grand general hospital." NCGM
specializes in treating AIDS, infectious and immune diseases
such as hepatitis, metabolic diseases such as diabetes, childand adolescent psychiatry. It also functions as a general
hospital that is able to handle any disease or condition,
including cancer and stroke, amidst Japan’s increasingly
aging population.
The third G stands for "Gateway to the precision medicine."
Particularly in genome medicine, NCGM systematicallyretains the samples of many diseases in the Biobank to utilize
along with clinical data in our R&D activities.
In response to the outbreak of COVID-19 in January 2020,
NCGM functioned as the National Center for handlinginfection crisis. We undertook wide-ranging measures
including the establishment of PCR test sites, the provision ofadvanced medical services for patients in moderate to severe
condition, the development of new drugs and plasma therapy
from recovered patients, support in hotel accommodations
for patients in mild condition, and the handling of infection
clusters on cruise ships. In particular, NCGM fully exercised
its capabilities as a general hospital for advanced medicine
in the treatment of patients in severe condition and clinical
trials for therapeutic drugs. The NCGM Research Instituteis undertaking the analysis of COVID-19 severity factors
utilizing the Biobank, the design of new drugs targeted at
COVID-19, and the development of vaccines and plasma
therapy from recovered patients.
We at NCGM will continue to respond to infectious diseases
and other healthcare crises while promoting advanced
medicine and R&D activities through close collaboration
between the general hospitals and the Research Institute,as well as human resource development and international
cooperation.

MESSAGE FROM THE PRESIDENTNCGM contributes to the promotion of people's health and welfare in Japan and around the world in the fields ofhealth and medicine, research, education and international cooperation, while respecting human dignity.

Message from the President

4

SINCE 1868

Medical services supported by a historyof more than 150 years
Relocated to the present site (1929)

History and future of NCGM

July

April

April

May

November

April

April

May

October

HISTORY OF NCGM

May

October

Celebrated the 150th anniversary of foundation

1967

April

The Medical Examination Center was renewed andopened at the Center Hospital

1947

October

Established the Medical Genomics Center

1942

April

Renamed a National Research andDevelopment Agency NCGM
Renamed the Bureau of International
Health Cooperation

1920

2018

The Center Hospital was approved as anadvanced treatment hospital

Transferred to thepresent Ministry of
Health, Labour andWelfare, and became the
National Tokyo Daiichi
Hospital

National Sanatorium Nakano Hospital

2016

Renamed the International Clinical ResearchCenter the Center for Clinical Sciences

April

2016

International Medical Center of Japan

1993

1997

2001

2003

2004

October

April

April

April

October

Opened the International Epidemic
CenterOctober

2015

Renamed the International Epidemic Center
the Disease Control and Prevention Center

April

2012

Designated a medical institution for
specified infectious diseases

July

2012

Opened the National College ofNursing, Japan

September

2010

Reorganized as an Independent Administrative
Agency NCGM
Established the Diabetes Research Center andthe International Clinical Research Center
Established the tertiary department ofemergency medicine and critical care at theCenter Hospital

1988

2010

Opened the AIDS Clinical Center

1986

2008

Established the Research Center Hepatitis
and Immunology

1974

2008
Integrated into the International Medical
Center of Japan1954

National Center for Global Health and Medicine ( NCGM )Established the International
Medical Center of Japan
with Fumimaro Takaku as thefirst President

Relocated to thepresent site

5

1947

Renamed the National
Sanatorium Nakano Hospital

Renamed the Army Main
Hospital(1862 — 1922)

National Medical Center Hospital

Established the AIDS Medical
Information Center

The main hospital wasestablished

OGAI MORI

Ogai Mori was born in 1862, the first son of the Mori family,
which served as designated doctors for the Tsuwano feudal
clan. He was renowned for outstanding intelligence from hischildhood, and graduated from the School of Medicine, theUniversity of Tokyo, at 19 years of age in July 1881. He served
as the deputy army surgeon at the Tokyo Army Hospital, thepredecessor of the Center Hospital of NCGM, for about six
months starting from December 1881. Commemorating its
150th anniversary, NCGM awarded Ogai Mori with the title"Special Honorary President," and created a bronze statue tocommunicate his achievements to later generations.

Integrated into the National
Center of Neurology andPsychiatry

Opened a soldier hospital

NCGM and Ogai Mori

April

Transferred to the present
Ministry of Health, Labourand Welfare, and became the
National Nakano Sanatorium

December

DecemberEstablished the Department
of International Medical
Cooperation

March

NovemberTransferred to the present
Ministry of Health, Labour andWelfare, and started as the
National Kohnodai Hospital

May

OctoberTokyo Municipal Nakano
Sanatorium

July

March

Tokyo Municipal Sanatorium

October

1987

Renamed the National Medical
Center Hospital; Established
the Clinical Research
Department

1945

1945

Renamed Kohnodai
Army Hospital

1929

1936

Started the firstcomprehensive medical
checkup service in Japan

1873

1899

Renamed Kohnodai
Garrison Hospital

1871

1872

Opened a subsidiary nursing
school1868

National Medical Center Hospital

Kohnodai Hospital

Established as sick rooms
for the Soldier School, Tokyo
Army Development Wing

HISTORY OF NCGM

The National Center for Global Health and Medicine (NCGM)
has its roots in the soldier hospital established in the
Yamashita-mon gate in Hibiya, Tokyo, in October 1868. It was
relocated to the present site in Toyama district in 1929. After
World War II, the operation of the Hospital was transferred to
the Ministry of Health and Welfare (the present Ministry of
Health, Labour and Welfare), and its history as the National
Tokyo Daiichi Hospital began. The Hospital was known topeople as "Toichi" for many years. In October 1993, the National
Medical Center Hospital was integrated with the National
Sanatorium Nakano Hospital to establish the International
Medical Center of Japan, as the fourth national center inJapan to play a major role for promoting international healthcooperation. There was a reorganization in 2008, and the
Kohnodai Hospital of the National Center of Neurology andPsychiatry was renewed as the Kohnodai Hospital of theInternational Medical Center of Japan. The International
Medical Center of Japan was reorganized as an independentadministrative agency National Center for Global Health andMedicine (NCGM) in 2010, and was restarted as new general
hospitals for further pursuing highly advanced medicine.
NCGM was further reorganized as a national research anddevelopment agency in 2015. NCGM consists of the Center
Hospital, the Kohnodai Hospital, the Research Institute, theCenter for Clinical Sciences, the Bureau of International
Health Cooperation, the National College of Nursing, and othervarious organizations. NCGM undertakes research concerning
infectious and immune diseases, metabolic diseases such as
diabetes, provides advanced general medical services, promotesinternational cooperation in healthcare, and pursues thecomprehensive development of healthcare professionals.
As the frontline for response to COVID-19 in Japan, we at NCGM
will strongly promote R&D for the prevention and advanced
treatment of diseases, for the sake of the world and of the future.

National Tokyo Daiichi Hospital, front gate

National Sanatorium Nakano Hospital

Central ward of Center Hospital of the National Center
for Global Health and Medicine was completed in August 2010.

The International Medical Center of Japan in the 2000

Desk of Ogai Mori, Principal of the Military Medical College

6

RESPONSE
TO HEALTH CRISES

Response to Health Crises by NCGM

2003

Severe Acute Respiratory
Syndrome (SARS)

2009

Pandemic influenza (H1N1)

Based on accurate knowledge acquired through abroad range of experiences, we appropriately respondto increasingly diversified, complex health crises.

Starting with medical aid for the Cambodian refugee camp in
1979, NCGM has been active not only in Japan but also in theinternational community, sending emergency relief teams
to countries afflicted by natural disasters and infectious
diseases. In the early 2000s, NCGM assisted in controlling the
SARS epidemic in China and Vietnam. In addition to healthcooperation, NCGM has provided assistance in overall healthpolicies, including local health insurance systems (universal
health coverage), maternal and child health, and nurse
certification systems. NCGM has dispatched more than 4,500
staff members to 134 countries in total, mainly in Asia andAfrica. In 2020, it took a variety of measures to support the
response to COVID-19.
Medical aid for Cambodian
refugees

1995

Response2

3

Treatment

Development

The Great Hanshin-Awaji Earthquake occurred on January 17,
1995. The then Ministry of Health and Welfare dispatched several
medical teams consisting of staff at national hospitals to theafflicted areas. The then International Medical Center of Japan (thepresent NCGM) sent physicians and nurses to provide disastermedical services to afflicted people at a shelter established on thepremises of an elementary school in Nagata-ku, Kobe.

1996

1999

The Japanese Embassy was attacked by an armed group duringa ceremony organized by the Japanese ambassador to Peru,
and the group took about 700 persons hostage. The Japanese
government sent a medical team including physicians andnurses from the then International Medical Center of Japan(the present NCGM) to the site. The medical team provided
the hostages with physical and mental support, and treatedpatients with trauma caused during forced entry by the army.

After H1N1 was identified in Mexico at the end of April
2009, infection spread across the world. In response, NCGM
supported quarantine activities at airports and stop facilities,
aiming to streng then the quarantine system at Narita
International Airport. NCGM also sent its staff members
to the UN influenza coordination organization to provide
support for the prevention of the spread of infection in Asia.

2011

2017

The Great East Japan
Earthquake

Yellow fever in the Democratic
Republic of the Congo

The Great Hanshin-Awaji
Earthquake

The civil war and food crisis in Cambodia resulted in morethan 500,000 refugees. Refugee camps were establishedin the border area with the neighboring country (Thailand).
The Japanese government star ted to provide refugees
with medical aid in 1979. The then National Medical Center
Hospital (the present NCGM) dispatched physicians andnurses to treat gunshots, landmine wounds and other injuries.

The Japanese Embassy hostagecrisis in Peru

In November 2002, SARS broke out in Guangdong Province,
China, and spread to many countries including Vietnam andCanada. The Japanese government sent Japan Disaster Relief
Teams including physicians from the then International Medical
Center of Japan (the present NCGM) to Vietnam and China. At
the sites, the team undertook various support activities including
the provision of guidance for infection prevention and control, theestablishment of model hospitals, and the health management ofJapanese residents in the areas.

The Great East Japan Earthquake occurred on March 11,
2011. NCGM started dispatching disaster medical assistanceteams to Sendai and Kesennuma Cities, Miyagi Prefecture,
six hour s af te r th e o ccur re nce . Subs e que ntly, NCGM
dispatched a medical team consisting of various professions
to Higashi-matsushima City, and public health specialists tothe municipal health center, to provide healthcare support.
NCGM also concluded a cooperation agreement with the city,and is providing continuous support as of September 2020.

The government of the Democratic Republic of the Congodeclared the epidemic of yellow fever in June 2016, andrequested assistance from the international community.
In response to this request, the Japanese government
dispatched the first Infectious Disease Response Team, withthe participation of physicians from NCGM. At the site, theteam led a vaccination campaign and provided technicalsupport in screening, thereby contributing to the suppressionof yellow fever.

2019

2020

Ebola virus disease in the Democratic
Republic of the CongoRESPONSE TO HEALTH CRISESRESPONSE TO HEALTH CRISES

7

1979

1

Novel coronavirus infection(COVID-19)

Turkey Earthquake

In August 1999, a major earthquake occurred in Western
Turkey, and approximately 15,000 fatalities were confirmed.
In response, the Japanese government sent an international
emergency relief medical team including physicians andnurses from the then International Medical Center of Japan(the present NCGM) to the site. In the afflicted area, the teamestablished a temporary clinic to treat trauma and internaldiseases.

An epidemic of Ebola virus disease was identified in Eastern
Congo in June 2019, and WHO declared "Public Health
Emergency of International Concern." In response to thisdeclaration, the Japanese government dispatched theInfectious Disease Response Team, with the participationof physicians and nurses from NCGM. At the sites, the teamprovided technical support to strengthen the quarantine
system and offered guidance for infection prevention.

The COVID-19 infection broke out in Wuhan, China, andimmediately spread across the world. NCGM undertook
various activities such as conducting health checkup forJapanese people returning from Wuhan on chartered planes,
providing suppor t for infection control on the Diamond
Princess cruise ship, screening suspected patients, accepting
patients in moderate to severe condition, providing expert
advice to the administration, and supporting the operationof accommodation facilities for recuperation and monitor thehealth condition of patients.

8Organization Chart

Center Hospital

As a National Center for Advanced and Specialized
Medical Care, the Center Hospital of NCGM handles
inf e c t io u s dis e a s e s , m e t ab o lic dis e a s e s su c h a s
diabetes, and other chronic and intractable diseases,
while responding to various treatment needs in Japan’s
increasingly aging population. The Center Hospitalalso promotes the R&D and international expansion of
innovative drugs and medical devices, undertakes clinicalresearch of international standards in Japan, and plays acentral role in investigator-initiated clinical trials.

Center for
Clinical Sciences

The Center for Clinical Sciences consists of six
d e p a r t m e n t s: t h e D e p a r t m e n t o f D a t a S c i e n c e ,Depar tment of Clinical Research, Depar tment ofInternational Trial, Department of Clinical Research
Strategic Planning, Department of Regulatory Science,and Department of Epidemiology and Prevention. The
Center aims at contributing to the health promotion ofpeople by finding new therapies and proposing disease
prevention measures.

Kohnodai
Hospital

The Hospital was reorganized as the Kohnodai Hospitalof the International Medical Center of Japan on April
1, 2008, and was reorganized as an Independent
Administrative Agency Kohnodai Hospital of NCGM
on April 1, 2010. A general hospital open to the local
communit y, it provides highly advanced medical
ser vices, while also providing diagnosis, sur veys,
research and training ser vices regarding hepatitis,
immune and other diseases to Japan and the world.

Research
Institute

The National Center for Global Health and Medicine
Research Institute (NCGMRI) is an organization that was
first positioned as the core of the research department
as th e bas e for Japan’s inte r national h eal thc arecontributions. It was established in the National Center
for Advanced and Specialized Medical Care that was
opened by integrating the National Medical Center
Hospital with the National Sanatorium Nakano Hospitalin 1993.

Bureau ofInternational
Health Cooperation

The Bureau of International Health Cooperation wasestablished as the Department of International Medical
Cooperation in 1986 in order to promote international
cooperation in the healthcare field. Since then, theorganization has under taken various ac tivities incollaboration with the Ministry of Health, Labour andWelfare; the Ministry of Foreign Affairs; JICA; WHO andother institutions in Japan and around the world in orderto improve healthcare and public health in pursuit of asociety where people of all countries can live in health.

National
College ofNursing, JapanThe National College of Nursing was launched by the
Ministry of Health, Labour and Welfare in 2001. It is an
educational institution that trains nursing professionals
at the National Center for Advanced and Specialized
Medical Care. The College trains nurses and midwives
who have clinical abilities for nursing practice thatare required the National Center for Advanced andSpecialized Medical Care, which is responsible fornational policy medicine. Trainees also develop the ability
to make contributions to the international community.

To become an ideal National Center, we pursue research throughcooperation among a broad spectrum of departments.
The National Center for Global Health and Medicine (NCGM) consists of the Center Hospital, the Centerfor Clinical Sciences, the Kohnodai Hospital, the Research Institute, the Bureau of International Health
Cooperation, the National College of Nursing, and other departments. NCGM provides advanced general
medical services, and promotes diagnosis and treatment particularly concerning diseases that requireinternational handling. NCGM is a National Center for Advanced and Specialized Medical Care that
conducts surveys and research regarding international cooperation in health and medicine for suchdiseases and trains the relevant specialists in a comprehensive manner.

11

PAGE

21

● Dept. of Emergency Medicine

CenterHospital

Board ofDirectors● Stroke Center● Comprehensive Cancer Centerand Critical Care
● AIDS Clinical Center (ACC)● Nursing Dept.
● Disease Control and Prevention ● International Health Care
Center (DCC)
Center● AMR Clinical Reference Center ● Biobank● Medical Examination Center

PAGE● Dept. of Data Science● Dept. of International Trial● Dept. of Clinical Research● Dept. of Regulatory Science● Dept. of Epidemiology andPrevention

Strategic Planning● General Outpatient Services● Nursing● Clinical Examination Laboratory ● Nutrition Management● Specialized Outpatient Services ● Psychiatric Care

Kohnodai
Hospital

Human Resource
Strategy Center for
Global Health9● Child and Adolescent● Dept. of Tropical Medicine and Malaria● Research Center for Hepatitis and● Dept. of Refractory Viral Infections● Dept. of Research for Hepatic Diseases● Dept. of Gene Diagnostics● Dept. of Immune Regulation● Rehabilitation Center● Dept. of Intractable Diseases

Research
Institute

Auditors● Radiology● Dept. of Infectious Diseases

President

Center for
MedicalInformatics
Intelligence

Bureau ofInternational
HealthCooperation

and Therapeutics● Dept. of Regenerative Medicine● Dept. of Human Genetics● Diabetes Research Center● Dept. of Molecular Diabetic
Medicine● Dept. of Molecular
Metabolic Regulation● Dept. of Diabetic Complications● Diabetics Information Center

Psychiatry

Immunology

PAGE

27

● Dept. of Gastroenterology● Dept. of Immunology and Pathology● Hepatitis Information Center● Medical Genomics Center● Molecular Immunology andInflammation Project● Lipid Signaling Project● Stem Cell Biology Project● Pancreatic Islet Cell

Transplantation Project● Genome Medical Science Project

PAGE

31

● Dept. of Health Planning and Management● Dept. of Human Resource Development● Dept. of Global Network and Partnership● Institute for Global Health Policy Research

National
College ofNursing,Japan

23
ORGANIZATION CHARTORGANIZATION CHART

Center for
ClinicalSciences● Dept. of Clinical Research

PAGE● Global Health & Medicine● Undergraduate Nursing Course● Graduate School of Nursing● Training Center for Nursing Development● Research Center in Clinical Nursing

PAGE

35
10

Enhanced equipment, structures and human resource development that
support highly advanced medical services for the world and the future
1 Department of Hospital●Internal medicine●Psychosomatic medicine●Surgery●Head and neck surgery●Cardiology●Neonatal medicine●Cardiovascular surgery●Pediatrics●Pulmonary medicine●Infectious diseases●Diabetes●Endoscopy●Gastroenterology●Endocrinology●Nephrology

Total number of beds

749 beds

General ward

699 beds

Tuberculosis ward

22 beds

Psychiatry ward

24 beds

Infection ward

4 beds●Anesthesiology●Gynecology●Pathology●Ophthalmology●Plastic and reconstructive● Emergency medicine●Otolaryngology

surgery（43 departments in total）

2 Outpatient Reception

3 Electronic Medical Record (EMR) System

4 Clinical Research

In the outpatient unit, volunteers guidep a t i e n t s an d an s we r t h e ir qu e s t i o n sregarding procedures for examination. The
International Health Care Center has also
been established in response to the global
era, providing multilingual consultation
services to international tourists and nonJapanese patients living in Tokyo.

At the same timing of the new central
ward opening, we expanded our Hospital
information system from order Entry System
to EMR System. It allows us to share thepatient / medical information among eachsection, check the information automaticallyand provide safer and more advanced medical
services. Also, the accumulated medical
information can be referred and analyzed forthe secondary use.

Medicine has been advanced by learning
patients with various kinds of diseases,
which is still important in the present time
when medical technology has significantly
improved. By gathering and analy zing
clinical data with cooperation from patients
while ensuring confidentiality, our efforts
are focused on research and “Biobank”
promotion that can contribute to thedevelopment of future medicine.

A

B

C

D

E

F

G

H

I

J

K

L

A

Operating theater

In the central operating theater wehave totally 14 rooms (14 beds) for
surgical operation. Among them
one is negative pressure room forsurgery of infected patients, andsix rooms are for video-assisted
endoscopic, laparoscopic, andthoracoscopic surgery, and threerooms are bio-clean rooms.

E

Angiography andInterventional Radiology

At the Angiography and Interventional
Radiology (IVR) division, experienced
staff perform advanced vasculardiagnosis and IVR procedures using
the newest equipment.

I

Advanced medicine

The Department has 20 beds in aseptic
rooms, including four biological clean
rooms, performing hematopoietic stem
cell transplantation, chemotherapy,
and immunosuppression therapy.

11● Oral and maxillofacial surgery

B

ICU

The ICU consists of 10 beds (oneis a negative pressure room), andprovides postoperative managementof highly invasive surgeries, CCU, andcross-organ systemic managementof the most critically ill patients in
the Hospital in collaboration withintensivists and various departments.

F

Department of
Diagnostic Radiology

Diagnostic imaging is performed
by staff specializing in CT, MRI,
general radiography, gastrointestinal
fluoroscopy, nuclear medicine testing(scintigraphy and PET), and otherfields.

J

Pharmaceutical Department

In addition to the dispensing andpreparation of drugs, the Department
under t akes various oper ations
regarding drug therapy, including themanagement of drug information,
guidance for patients, and participation inteam care.

CSCU

The SCU has six beds dedicatedt o s t r o ke p a t i e n t s (t o b e
increased to nine beds). The
mul t i-p r o f e s s i o n c ar e t e am
evaluates patients' conditionand pursues early rehabilitation.

G

Radiation Oncology

The Radiation Oncology Department
provides patients with the latest
treatment techniques including
intensity-modulated radiationt h e r a p y, b r a i n s t e r e o t a c t i cradiosurgery and stereotactic bodyradiation therapy.

K

Laboratory Testing Department

Physiological and biochemical(emergency), general, blood,
immunological, microorganism,
blood transfusion, and otherlaboratory tests are performedin this laboratory.

D

Center HospitalCenter Hospital

Facility outline●Dentistry●Obstetrics●Neurosurgery●Rheumatology●Radiation oncology●Urology●Orthopedics●Allergy●Neurology

The Center Hospital is a National Center for Advanced and Specialized Medical
Care that was certified as an advanced treatment hospital in 2012. It provides
highly advanced medical services for infectious diseases (including emerging andreemerging infectious diseases, HIV and hepatitis), diabetes and metabolic diseases,
and other chronic and intractable diseases, and responds to the cancer treatment
needs that are becoming increasingly difficult amidst Japan’s increasingly aging
population. The Center Hospital also accepts the largest number of emergency
patients in Tokyo, with emphasis on emergency medicine. From the standpoint ofinternational health cooperation, the Hospital implements education and training
for physicians and nurses from overseas countries, and proactively examines
overseas tourists and non-Japanese residents in Japan. The Hospital is one ofJapan’s oldest post-graduate educational institutions and represents the country
internationally. It proactively implements early-stage education and post-graduate
education for physicians, medical interns, and nurses. The Hospital also focuseson promoting clinical research as a national research and development agency.

surgery●Pain clinic

Rehabilitation●Radiology●Dermatology●Pediatric surgery●Palliative care

●Physical medicine and●Psychiatry●Gastroenterological●Dialysis●Hematology

Center Hospital●Thoracic surgery

NICU・GCU

The Neonatal Intensive Care Unit
has six beds, and the Growing
Care Unit also has 12 beds, forthe ge ne ral manage me nt of
newborns.

H

Endoscopy

The department is fully equippedwith endoscopic devices of theworld's highest standard, andprovides safe, secure medicine
and thorough preventive measuresagainst infectious diseases.

L

Special Private Room Ward

This ward is located on the highest
floor and is fully equipped withsecurity functions. We provide
inpatients with comfortable living
full of hospitality during their
stay.

12

Department ofEmergency Medicine
and Critical Care

Entrance to the outpatient unit of
Department of Emergency Medicine andCritical Care

Healthcare professionals cooperation for asevere patient care

T he A I DS C l i n ic a l Ce nt e r ( ACC) w a s e s t a bl i s he d i n A pr i l
1997, fol low ing t he set t lement of a suit fi led by hemophi lia
patients infected with HIV via contaminated blood products,
for t he purpose of not only prov iding t he relief measures tothe hemophilia patients but also ensuring access to HIV care
for a l l people l iv i ng w it h H I V r ega r d less of t hei r r outes ofinfect ions. ACC prov ides a mult idisciplinar y care by a teamof va r ious hea lt hca r e pr ofessiona ls, i nclud i ng coor d i nator
nurses, clinical psychologists, or medical social workers. ACC
has a lso an outpat ient clinic for t he comprehensive care ofHIV-infected hemophilia patients, and opened a sexual healthclinic in 2017 to promote preventive medicine against sexuallytransmitted infections. ACC has a research laboratory and has
actively conducted clinical and basic researches on HIV and its
comorbidities, including those of international research projects
in other Asian countries, which led to more than 400 publications
on scientific journals. Our goal is to be among the world’s leading
hospitals of HIV care.

In-situ-simulation training of advance life support

Heliport on the roof top of the Center
Hospital

The team of our department

13

Gene analysis at the ACC lab

Outpatient consultation rooms that provide
privacy

Clinic for hemophilia patients that provides
comprehensive care

Center HospitalCenter Hospital

The Department of Emergency Medicine and Critical Care comprises
the three departments of Emergency Medicine, General Medicine
and Intensive Care Unit, along with the Trauma Center and theSimulation Center. The Department practices our philosophy of"providing safe medical services that satisfy the needs of local society
as a tertiary emergency medical facility for the community thattreats any kind of emergency patients with any severity around theclock based." At present, we respond to approximately 11,000 patientstransferred by ambulance every year, about 11% of which require
critical care, mainly from the western part of the 23 wards of Tokyo.
The Hospital also functions as one of the disaster bases in Tokyo.
The Emergency Medicine is divided into the outpatient unit andthe inpatient ward. The outpatient unit has equipment required foradvanced resuscitation, including two resuscitation rooms, six beds
for stable patients and a decontamination area with a depressurized
isolation room. Besides doctors, nurses and coordinators, medical
technologists also work at night in the outpatient unit, enablingprompt blood transfusion, microbiological tests, and physiologicaltests. The inpatient ward is equipped not only with 13 beds for criticalcare including an isolation area, but also 19 beds for stepdown
including four beds with isolation. In the same floor of the inpatientward, there are in-situ, well-equipped, simulation training rooms forthe liberal use by healthcare workers.

AIDS Clinical Center(ACC)

The Sexual Health clinic

Weekly clinical conference

14Disease Control
and Prevention Center(DCC)

AMR Clinical ReferenceCenter

The Disease Control and Prevention Center (DCC) was established in May
2012 by integrating the Department of Infectious Diseases (establishedin July 2011 ) into the International Epidemic Center (established in
the then International Medical Center of Japan in October 2004 ) forthe purpose of preventing the spread of emerging and reemerging
infectious diseases in Japan.
DCC comprises the Department of Infectious Diseases, Travel Clinic,
International Infection Control Room, and Antimicrobial Resistance(AMR) Clinical Reference Center (see the right). To cope with infectious
diseases that require high specialization and infection issues inJapan and overseas, DCC undertakes the treatment and prevention of
infectious diseases, training of infection specialists, epidemiologicalresearch, the development of diagnostic methods and drugs/vaccines,
and comprehensive advanced initiatives to improve awareness among
the general public.
DCC promotes its activities on various occasions in clinical settings, R&D
stages and medical policies, based on collaborations with specialists ineach field in the National Center for Global Health and Medicine.

Conference of infection specialists
before the EAS ASEAN Summit

2 Human Resource Development

Clinical Infectious Diseases

Seminar and Training Course

In collaboration with General Medicine, DCC provides care to
inpatients and outpatients with infectious diseases as well as
those who may possibly be infected. DCC manages the Infection
Consultation Group to support the care of infected patients in otherdepartments of the Hospital.

DCC also holds seminars concerning emerging and reemerging
infectious diseases, travel medicine, and vaccination.

Travel Clinic
Our Travel Clinic provides travelers with pre-travel health check,
immunization, and post-travel care. It is also an official yellow
fever vaccine center.

Preparedness for Emerging Infectious Diseases
DCC establishes an internal system in preparation for new
infectious diseases, supports care at medical institutions inJapan and overseas, and conducts research concerning measuresagainst emerging and reemerging infectious diseases.

Exhibition at the NCGM Atrium

Center HospitalCenter Hospital

1 At the Center Hospital

The AMR Clinical Reference Center (a project entrusted from the
Ministry of Health, Labour and Welfare) was established in April
2017 in order to promote initiatives based on the National Action
Plan on Antimicrobial Resistance (AMR). This Center consists of
t hree divisions, in which diverse staff members are engaged in
AMR stewardship while making use of their respective specialties.
The Clinical Epidemiology Division sets up and operates healthcare
surveillance systems, and undertakes the surveillance of elderly carefacilities. The Center also centralizes data from the viewpoint of a
one-health approach, in consideration of the necessity for monitoring
animals and the natural environment to protect human health. The
Pharmacoepidemiology Division surveys the doses of antimicrobials
nationwide, and discloses the results of the surveillance. The Divisionalso collects and analyzes data concerning antimicrobial stewardship.
The Information and Education Division implements educational
activities concerning AMR and antimicrobial stewardship, including
seminars for healthcare professionals and the preparation of relatedmaterials. The Division also provides information to the generalpublic on its website and at related events.

Human Exchange
We have accepted trainees from overseas and worked on infectious
diseases in foreign countries.

Residency and Fellowship Program
Since 2010, DCC has accepted senior clinical residents (for thegeneral infection program) in collaboration with the AIDS ClinicalCenter and Pulmonary Medicine. In 2012, DCC opened a clinicalfellow program for post-senior resident physicians, and has
annually accepted three to four physicians in the sixth year after
graduation or later in order to train them as infection specialists.

Information provision on the website

Discussion at the Pharmacoepidemiology Division

Staff at the Clinical Epidemiology Division

Educational activity at an elementary school

3 Research
Overseas: Research on the control of multidrug-resistant bacteria at base hospitals in Vietnam
Domestic:D CC conducts many multicenter clinical research projects on new test methods, unapproved drugs, bloodstream infection,etc. for COVID-19, other emerging and reemerging infectious diseases, and imported infectious diseases. DCC also proactively
conducts investigator-initiated clinical trials regarding new antimicrobial agents. DCC participates in GeoSentinel, the global
surveillance network for the epidemiological research of travel-associated infectious diseases.

Training at a new infectious disease ward

15

Training seminar

16

Medical Examination
CenterStroke Center

The comprehensive medical checkup service in Japan was started
on July 12 , 1954 , as a "short-term hospitalized high-precision
physical examination" at the National Tokyo Daiichi Hospital,
the predecessor of our Hospital. Subsequently, this system
expanded across Japan, referred to as "Ningen (human) Dock."
In May 2016 , the Medical Examination Center was establishedbased on our achievements and experience over years. It was a
new step toward more precision checkup service at our National
Center. To promote t he ea rly detect ion a nd pr event ion oflifestyle-related diseases, our center provides an enhanced basic
examination. At the same time, many innovative tests have been
introduced including nasal endoscopy, CT colonography, pancreas
The staff members of Medical Examination Centerand liver “dock”, neck vessel assessment, and enhanced brain
examination incorporating cognitive function assessment. The Medical Examination Center proactively collaborates
with clinical departments in our Hospital, to strengthen links with subsequent medical services.

The Center pursues the world's highest class medical services by
providing high-precision examination by skilled technologists,
utilizing the latest equipment and medical devices. The reportsof comprehensive medical checkups are prepared by dedicatedphysicians who specialize in examinations and preventive
medicine. Reports incorporate comprehensive assessments thatlead to subsequent treatment and lifestyle improvements basedon the results of examination by specialists in the respective fieldsof related departments.
If a disease is identified, patients are able to receive a prompt,
det aile d examination and undergo advance d, sp e cialize dtreatment at our Center. Upon request from examined persons,
we can also introduce the patient to other hospitals on medical
services.

Providing comprehensive medical

In t his e r a of g l o b aliz a t i o n , o ur C e nt e r a cce p t s n ot o nl yJapanese but also many overseas clients who want to receive acomprehensive medical checkup, in order to promote preventive
medicine from a global viewpoint. We have an outstanding
track record in the number of overseas clients accepted among
medical examination facilities in Japan. We provide high-quality
comprehensive medical checkups to overseas clients just as todomestic clients, aiming at seamless collaborations in medical
services by effectively utilizing our abundant connections withoverseas healthcare professionals in cooperation with theInternational Health Care Center.

Our Medical Examination Center offers abundant additional options according to the requests and convenience of persons who receive
examinations. They can select from a one-day examination or a hospitalized examination. It is possible to select from a variety of options
that target the early prevention of arteriosclerotic diseases, in addition to the early detection of malignant tumors.

17

PET/CT scanner

Rehabilitation Room dedicated to the Stroke Center2 checkups to overseas clients

3 Abundant additional options

Private room for hospitalized examination

SCU

Center HospitalCenter Hospital

1 Characteristics of our Medical Examination Center

Recently, thrombectomy has emerged as a therapy for acute cerebral
infarction, w it h which dramatic improvement in sy mptoms can be
expected. In response to this substantial paradigm shift, our Hospital
opened an SCU with six beds in December 2014 (to be increased to nine
beds in April 2021 ), and has contributed to the local communit y byproviding cutting-edge treatment to local patients with acute strokes who
are accepted as far as possible on a 24 / 7 basis. In September 2019, our
Hospital was officially certified as a primary stroke center by the Japan
Stroke Society for these achievements over many years. We are required toguarantee the quality of stroke medicine by measuring clinical indicators
on a periodic basis. At our Hospital, stroke treatment is conducted bya multi-profession team that consists of neurosurgeons (five advisors
and two or three specialists), endovascular treatment physicians (oneadvisor and one specialist), neurologists (three specialists), rehabilitation
physicians, emergency physicians, physical therapists, occupational
therapists, speech-language-hearing therapists, radiologists, nurses,
pharmacists, registered dietitians, and MSWs. The team provides highly
specialized treatment immediately following onset.

Endoscopy system

Comprehensive Cancer
Center

Led by oncologists and in collaboration with related departments,
the Center not only provides the best treatment for each cancer
patient, but also operates Cancer Survivorship Support recovering
cancer patients and Palliative Care for specialized palliation ofpain and other agonizing symptoms. As a general hospital thathas specialists in each department, we treat cancer patients who
have various comorbidities such as the deteriorated functionof the heart, kidneys, or liver; mental/ner vous diseases; andinfectious diseases. We provide treatment tailored for each patientby properly assessing organ functions and other conditions before
treatment, and estimating pharmacokinetics and other factorsthat match the properties of drugs. To provide safe treatment with
anticancer medicines and achieve maximum effects, it is necessary to obtain knowledge and experience from specialists
in each department—who are capable of optimal responses to various adverse reactions—as well as from specialized
oncologists, palliative care specialists, certified nurses for chemotherapy, and pharmacists who specialize in oncology.
Our Hospital has all these necessary factors. Therefore, we can propose the optimal treatment and management for eachpatient and make possible precision medicine.

18International HealthCare Center

Nursing Department

1 Principle of the Nursing Department

2 Goals of the Nursing Department

To respect life and humanity, both of which are irreplaceable, andstrive for warm-hearted nursing.

1. To focus efforts on providing safe and high-quality nursing
2. To create nursing through promoting nursing education and research
3.	 To diligently strive for nursing that can adapt to changes in medical
science3 To develop and improve practical and clinical skills
The Center Hospital is an advanced acute care hospital based oncomprehensive model care and provides advanced, pioneering
medical services. In the Nursing Department, we develop talented
generalists and specialists under their specified philosophy. To
develop human resources capable of providing "warm nursing
care," we consider it important to establish an environment thatvalues each nurse and enables them to actively provide nursing
care. Aiming at high-quality nursing practice, we upgrade theskills of clinical practice among nurses, while implementing
enhanced medical safety training. We also promote and support
clinical research on nursing.

To ef f icient ly t reat non-Japa nese nat iona ls at t he Center
Hospital, the International Health Care Center (ICC) undertakes
coordination between non-Japanese patients and more than 40
clinical departments/centers.
ICC members includes three medical coordinators and some 15
medical interpreters/translators (in English, Chinese, Vietnamese,
Nepalese, and Myanmar languages). They are supporting face-toface medical consultations for overseas visitors and non-Japanese
residents who cannot adequately understand or speak Japanese,
as well as for overseas residents who want to see doctors in our
Hospital.
An increasing number of non-Japanese patients visit the Center
Online steering committee meeting held to ef ficiently
Hospital year by year. In FY2019, non-Japanese nationals accounted
treat non-Japanese nationals at the Center Hospitalfor 13 .9 % ( 5,656) out of all first-visit patients, and 6. 5% ( 1 ,163) of
all newly hospitalized patients. Medical interpretation service by external service providers is also available in 19 languages
via phone or tablet.
We are also endeavoring to provide training of medical interpretation and exchange information through internal on-thejob training and annual online training for medical interpreters.
Center HospitalCenter Hospital

Biobank

Biobank is a nonprofit mechanism (research platform) for
retaining cells, genes, tissue and other research resources over along period to be utilized in unspecified medical research projects.
The NCGM Biobank is operated at the Center Hospital (Toyama,
Shinjuku-ku) and the Kohnodai Hospital (Ichikawa City, Chiba).
The Biobank asks patients to provide biological samples (such as
blood and surgical tissue) and medical information, with theirunderstanding and consent, and retains the samples under proper
management for medical research to help future treatment.
Through the Biobank, we aim to utilize the retained samples andinformation in various research projects in the present and in the
future, toward the clarification of disease factors and conditions,
Retention of samples
as well as the development of new drugs, so that more advanced
medical services can be provided and more diseases can be cured in the future.
NCGM and the five other national centers for advanced, specialized medical research jointly operate the National Center
Biobank Network in order to support more disease-specific research projects.

1920

Talented researchers at NCGM support clinical research and trials

1 Department of Data Science
This Department pursues improvement in the quality of clinicalresearch by implementing biostatistics, data science research andeducation/training activities that are indispensable for scientificclinical research. The department also supports researchers
through biostatistics consultation service and the operation of
the data center at the Joint Center for Researchers, Associates
and Clinicians.

2 Department of Clinical Research

3 Department of International Trials

The Center for Clinical Sciences consists of six depar t ments: t he Depar t ment of
Data Science, Department of Clinical Research, Department of International Trials,
Depar t ment of Clinical Research St rategic Planning, Depar t ment of Reg ulator y
Science, a nd Depa r t ment of Epidem iolog y a nd P r event ion. The Center a i ms tocontribute to the health promotion of people by creating new therapies and proposing
disease prevention measures. To achieve this goal, we proactively undertake sponsorinitiated clinical trials, while pursuing solutions for unmet needs in medical settings
through investigator-initiated clinical trials. We also conduct a wide range of research
activities, from the development of vaccines and test methods to the prevention of
disease onset. As the center of clinical and research activities to combat COVID-19, we
undertake advanced, innovative research in order for society to restart its activities.

This Department promotes the R&D of drugs, medical devices andevidence-based medicine in cooperation with other countries.
To provide better medical services to patients across the world,
this Department contributes to global health through various
activities including international clinical research and trials,
human resource development, industry-academia-government
collaborations and regulatory affairs.

Center for Clinical Sciences

Center for Clinical Sciences

Center for Clinical
Sciences

This Department undertakes practical support, administrationand education/training for clinical trials and research. As a general
hospital, NCGM has implemented clinical trials across a broad
range. This Department also provides support to conduct highquality, ethical clinical research, such as consultation service forclinical research planning by researchers at NCGM.

4 Department of Clinical Research Strategic Planning
For the R&D of therapies and medical devices, the Departmentp r o m o t e s a n d s u p p o r t s i n d u s t r y-a c a d e m i a -g ove r n m e n tcollaborations with a particular focus on contractual affairs andthe acquisition of intellectual property rights. The Department
also holds events for connecting researchers with companies, andprovides incubation support to companies that seek international
business expansion.

5 Department of Regulatory Science
The Department provides advice based on pharmaceutical regulations, ranging
from the initial development stage of drugs and medical devices to the safety
management of clinical studies. The Department also focuses on human resource
development in the regulatory science field, based on the comprehensive
partnership agreement with the Pharmaceuticals and Medical Devices Agency.

6 Department of Epidemiology and Prevention
This Depar tment focuses on research regarding the preventionof diabetes and other lifestyle-related diseases. The Department
promotes a large-scale cohort study in the relevant field, a resident
cohort in Vietnam, and a COVID-19 antibody survey on NCGM staff.

21

22

Supporting the local community and the future with highly advanced medical
services

1 General Outpatient Services
As a general hospital open to the local community, the Hospitalhas departments for Internal Medicine, Surgery, Neurosurgery,
Cardiovascular Surgery, Orthopedics, Dermatology, Urology,
Gynecology, Ophthalmology, Otolaryngology, Anesthesiology/
Pain Clinic, Rehabilitation, Psychiatry, Child and Adolescent
Psychiatr y, Radiolog y, Dentistr y, and Emergency Medicine.
Specialists in each field provide examinations to patients.

Kohnodai Hospital

The laboratory testing division provides physiological tests,
including ultrasonography; laborator y test s, including
bacteriological tests, and pre-transfusion tests; and pathologicaltests, including pathological anatomy. The division is designatedas a training center by the Japanese Society of Laborator y
Medicine sponsored by the Japan Medical Association, theJapanese Society of Pathology, and the Japanese Society ofClinical Cytology.

Kohnodai Hospital

Kohnodai Hospital

On April 1, 2008, the Hospital was recognized and renamed International
Medical Center of Japan Kohnodai Hospital, which later became incorporated
a nd r ena med t he Nat iona l Center for Globa l Hea lt h a nd Med ici ne
Kohnodai Hospital on April 1, 2010. Kohnodai Hospital, as a general hospital
opens to t he communit y, prov ides advanced medical ser v ices. It also
provides, both in Japan and abroad, diagnostic ser vices, sur veys, studies
and t raining mainly relat ing to hepat it is and immunologic diseases.

2 Clinical Examination Laboratory

Facility outline
Total number ofbeds

417 beds

General ward

277 beds

Psychiatry ward

140 beds

3 Specialized Outpatient Services
In addition to the general outpatient services, more advanced,
specialized medical services are provided in Internal Medicine,which comprises General Internal Medicine and specialized
outpatient units including Pulmonary Medicine, Hematology,
Infectious Diseases, Diabetes and Endocrinology, Rheumatology
and Collagen Diseases, Nephrolog y, Gastroenterolog y andHepatology, Cardiology, Psychosomatic Medicine and Neurology.

4 Radiology
The Radiology unit provides the optimal general medical services
using the state-of-the-art medical devices. The unit proactively
promotes medical collaborations with the local community,
making contributions with its cutting-edge medical technology.
When patients require precise diagnosis, the unit performs rapid
and advanced diagnostic imaging with various imaging devices(such as MDCT, MRI, PET/CT and SPECT).

23

24

Satisfying the health needs of local residents from a multifaceted viewpoint

9 Team Care

5 Rehabilitation Center

At the Kohnodai Hospital, borders are low among clinicaldepar tment s, enabling dif ferent professionals (including
physicians, nurses, workers, psychologists, rehabilitation staff,
registered dietitians and pharmacists) to easily collaborate andexercise their respective specialties.
Collaboration enables the professionals to provide care while
respecting the QOL and will of patients.
The Hospital also has an ensemble that plays musical instruments
to provide relaxation for local residents.

This Center has the Physical Therapy Room, (Physical and
Mental) Occupational Therapy Rooms, Speech-L anguageHearing Therapy Room, and Day Care Room. Each Room satisfies
the relevant Disease-specific Facility Standard I, and pursues
improved QOL for patients with physical dysfunctions. In addition
to physical dysfunctions, the Center also provides characteristic
rehabilitation services including various disorder assessments andtreatment for the dysfunctions of patients with mental diseases.

6

Nursing

Emergency psychiatry and comprehensive

10 psychiatric care

The Psychiatry Unit has outpatient functions to treat all typesof mental disorders. In addition, a psychiatry emergency caresystem provides 24/7 ser vices. We provide comprehensive
psychiatric treatment for physical complications and complex
diseases through collaboration between Psychiatry and various
other departments.

7 Nutrition Management

Emergency medical services and collaboration

11 with community healthcare professionals

The Clinical Nutrition Management Department is responsible fornutrition and diet therapy and food service management, which
is fundamental to the treatment of all diseases. The Department
provides advanced and specialized instructions about nutritionand diet to patients mainly with lifestyle-related diseases,
psychosomatic eating disorders, psychiatric complex disorders
both individually and collectively on an inpatient and outpatientbasis and under the community support system, and involves inclinical nutrition research and other wide range of activities.

Development of professionals in both highly

8 specialized and general medicine

The Kohnodai Hospital not only introduces advanced facilities andtechnologies, but also devotes its energies to the developmentof individuals who can utilize them effectively. Various crossfunc tional training sessions and seminars are provided, in
addition to study meetings within the respective sections. Eachstaff member increases their highly specialized skills, at thesame time improves their capabilities as staff of a national center
provide general medical care by increasing their interest in otherspecialized departments.

25

Kohnodai Hospital

Kohnodai Hospital

The Kohnodai Hospital has wards for general diseases and mental
diseases, and provides everyday care for the life and mind ofpatients. To provide mental and physical nursing care to patientsand their families, both new and experienced nurses exchangehonest opinions and repeatedly practice, receive education, train,
and conduct research. The unit also holds nationwide seminars
and trains human resources in the fields of child and adolescent
psychiatry, eating disorders, hepatitis and immune diseases.

We actively accept emergency patients who require immediate
attention. We will continue to reinforce our emergency medical
services as a mission that every medical institution must notforget . Our outpatient depar tment places impor tance on
collaboration with community healthcare professionals to offer
advanced testing, diagnostic imaging services and instruction
nutrition and diet.

12 Child and Adolescent Psychiatry
The Kohnodai Hospital has treated and supported children andadolescents since 1948 to date. In particular, the Hospital is the
only national center that has a ward specializing in child andadolescent psychiatry. It has undertaken hospitalized treatment
and other clinical activities, and also trains specialists in child andadolescent psychiatry. The Hospital also vigorously collaborates
with specialized institutions in Japan and overseas, supports
areas afflicted by natural disasters, and conducts various clinicalresearch projects.

26Researchers constantly work to combat infectious diseases, diabetes/
metabolic diseases, and hepatitis/immune diseases
Feature of the Research Institute
NCGMRI consists of 14 research departments, 5 project
research units, 3 research centers, and 2 information centers
as well as a common equipment/service facility, an animal
research facility, and a radioisotope facility. In the Institute,
approximately 180 staff members are engaged in research
activities, including 36 department chiefs/managers and 80
senior researchers.
The International Infectious Disease Division of the Institutepr imar ily focuses on t he development of diagnost ics
and new drugs in fight with emerging and reemerging
infectious pathogens. The efforts by the Advanced Medicine
Development Division center on the development of advanced
knowledge and skills while the Division brings for wardtranslational research using the state-of-the-art technology

Research InstituteDepartments●Dept. of Tropical Medicine

and Malaria●D ept. of Infectious Diseases●Dept. of Refractory Viral
Infections●Dept. of Intractable Diseases●Dept. of Gene Diagnostics
and Therapeutics●Dept. of Regenerative
Medicine●Dept. of Human Genetics●Diabetes Research Center●Dept. of MolecularDiabetic Medicine●Dept. of Molecular

Metabolic Regulation●Dept. of Diabetic
Complications●D iabetics Information
CenterHepatitis and Immunology●Dept. of Research for
Hepatic Diseases●Dept. of Gastroenterology●Dept. of Immune Regulation●Dept. of Immunology andPathology●Hepatitis Information Center●Medical Genomics Center●Molecular Immunology

and Inflammation Project●Lipid Signaling Project●Stem Cell Biology Project●Pancreatic Islet Cell

Transplantation Project●Genome Medical Science

Project

Electron micrograph of a normal mouse liver sinusoidal
endothelial cell

Electron micrograph of a pancreatic islet beta cell
Many insulin granules are obser ved in the cytoplasm

VeroE6 cells infected by SARS-CoV-2 stain in green (showing
the presence of virus antigens), while cellular nuclei in blue

X-ray crystal structure of GRL-2420, an inhibitor of
SARS-CoV-2’s main protease (M pro), complexed with M pro

X-ray crystal structure of AZT, the firstdr ug for A IDS , compl e xe d wi t h HI V ’s
reverse transcriptase

27●Research Center for

Multidrug-resistant Pseudomonas
aeruginosa

Research InstituteResearch Institute

The National Center for Global Health and Medicine Research Institute (NCGMRI) was establishedin the National Center for Advanced and Specialized Medical Care that was opened by integrating
the National Medical Center Hospital with the National Sanatorium Nakano Hospital in 1993.
NCGMRI is an organization that was first positioned as the core research department forinternational healthcare contributions in Japan, with the mission to promote researchin all fields of health and medicine that require international cooperation. NCGMRI
promotes international research cooperation with developing countries and other overseas
countries, and also undertakes basic and clinical research projects in collaboration
w it h t he Hospital and t he Bureau of Internat ional Healt h Cooperat ion regarding
diseases that pose urgent issues in developing countries (such as infectious diseases andnutrition disorders). NCGMRI also contributes to the development of human resources
for international medical research by accepting trainees f rom Japan and overseas.

in collaboration with clinical departments of NCGM.
The Diabetes Research Center at tempts to clarif y t hemechanism of diabetes and its complications and improve
the treatment of such abnormalities. The Research Centerfor Hepatitis and Immunology focuses on the identificationof new therapeutic modalities of hepatitis, liver cancer, andimmune diseases. The Medical Genomics Center promotes
research to develop genome-based medicine for clinicalapplications.
In response to the late 2019 outbreak of novel coronavirus
infect ion (COV ID- 19 ), NCGMRI immediately launchedmultiple new research projects to fight with the pandemic
in close collaboration with NCGM Hospital, signifying theInstitute’s ability to agilely respond to public health threat.

Red blood cells infected with humanmalaria parasites

28Research Center for
Hepatitis and
Immunology

Diabetes ResearchCenter

The Diabetes Research Center was established in 2010 to attain the
missions of clarifying the factors for diabetes and developing new
methods for diagnosis and treatment.
This Center consists of three research departments (the Departmentof Molecular Diabet ic Medicine, Depar t ment of Molecular
Metabolic Regulation, and Department of Diabetic Complications),
the Department of Pancreatic Islet Cell Transplantation, and the
Diabetes and Metabolism Information Center for human resource
development, information provision and policy research. To attainits goals, the Diabetes Research Center undertakes basic researchconcerning diabetes, clinical research for J-DOIT3 and PRISM-J,
large-scale registry research projects including J-DREAMS, andImmunohistochemical staining of the pancreatic islets
other research activities on each level, and promotes projects in anof Langerhans for insulin secretion
integrated manner to bring the research achievements to society.
The Center links medical services in the Hospital with research
activities at the Research Institute, promotes information provision concerning diabetes, and strives for further development
as the central base of diabetes research and practice in Japan.

Viral hepatitis is an infectious disease of the largest scale in Japan. When left
without appropriate treatment, hepatitis becomes chronic and may lead tocirrhosis or liver cancer. Therefore, national measures are required from theviewpoint of patient relief and the reduction of medical expenses. The ResearchCenter for Hepatitis and Immunology consists of four research departments(Hepatic Disease, Immunolog y and Patholog y, Immune Regulation, andGastroenterology), the Department of Genome Medical Science, and the
Hepatitis Information Center. This Center has human resources and research
instruments of the highest class in Japan for hepatology, immunology andgenome sciences, and undertakes cutting-edge research projects around theworld. The research departments aim at contributing to the health and welfareof people by developing methods for diagnosis and treatment by clarifying thepathology of viral hepatitis, cirrhosis and liver cancer, autoimmune diseases,
and allergic diseases. The Hepatitis Information Center was established basedon the Basic Act on Hepatitis Measures. The Center endeavors to make hepatitis
medicine uniform and promotes hepatitis policies in collaboration with the
Ministry of Health, Labour and Welfare, municipal governments nationwide,
and the 71 cooperating hospitals for liver disease treatment across Japan.

Cell culture
experimentState-of-the-art
research equipment

Laboratory

Research InstituteResearch Institute

Medical Genomics
CenterBriefing seminar for participants in the
PRISM-J project

J-DREAMS project

Diabetes awareness improvement event heldin concurrence with National Diabetes Week
and World Diabetes Day
Meeting to develop new diabetes therapies
Genetic counseling at the Genomic Medicine Department, Center Hospital

In recent years, a paradigm shif t from traditional medicine
to precision medicine has been advocated. Genomic medicine
is positioned as a core approach for this paradigm shift. The
Medical Genomics Center (MGC) was established in April 2016 as
an organization for the development and promotion of genomic
medicine in the National Center for Global Health and Medicine.
MGC implements both medical research and clinical application,and contributes to the practice in collaboration with the Genomic
Medicine Department of the Center Hospital.
The terms "genet ic tests" and "medical genet ics" have beencommonly used. Broadly speaking, "genomic tests" and "genomic
medicine" are a developed version of those terms. Genetic tests
Clinical interpretation of genome variant information
examine the DNA fragments of specific genes, and are mainly
targeted at hereditary diseases. On the other hand, genomic tests handle genome information for the exhaustive explorationof a variation (group) of focused diseases. The targeted diseases have been gradually increased. MGC tackles diverse
requirements in accordance with the progress of genomic R&D and genomic medicine in Japan and overseas, in a strategic
and agile manner.

29

30

Care, commitment and communication for a healthier world
1 Innovative international health cooperation
The Bureau promotes comprehensive technical cooperation to resolve public health crises and health issues in low and middle income
countries and all other countries and regions, and to reduce health disparity. The Bureau promotes innovative health cooperation incollaboration with various stakeholders including companies, NPOs and international partners.

2 Thinktank function in the global health area
The Bureau cooperates in the global health diplomacy of Japan, making policy proposals based on its knowledge and experience with global
health. The Bureau also sends committee members to expert meetings at the WHO and other international institutions. In addition, it shares
knowledge as a WHO Collaborating Centre and provides knowledge through international conferences.

3 Human resource development that takes into account global health trends
The Bureau has developed trainees from low and middle income countries into human resources capable of coping with various health issues and publichealth crises. It has also established a network of such human resources. The Bureau also implements practical classes and training courses in collaboration
with Japanese and international institutions in order to develop Japanese human resources in health capable of acting in global settings.

The Bureau of International Health Cooperation strives for improvements in healthcare and public healthin pursuit of a society where people of all countries can live in health. The Bureau of International Health
Cooperation was established as the Department of International Medical Cooperation in 1986 in order topromote international cooperation specializing in healthcare. Since then, the organization has undertaken
various activities in collaboration with the Ministry of Health, Labour and Welfare; the Ministry ofForeign Affairs; JICA; WHO and other institutions in Japan and around the world. To date, the Bureau has
implemented technical cooperation projects based on the Official Development Assistance in 26 countries,
and has accepted approximately 6,000 trainees from more than 160 countries. In recent years, increasing
measures have been taken for infectious diseases, maternal and child health and enhanced healthsystem, as well as non-infectious diseases, the aging of society, and response to public health crises. As
the promotion of Sustainable Development Goals and Universal Health Coverage is considered important,the Bureau promotes international health cooperation in a cross-division, comprehensive approach.

The Bureau promotes research that contributes to solving global health issues through the strategic use of partner institutions and various
networks in Japan and overseas. To implement international health cooperation in an effective, efficient manner, the Bureau also undertakes fieldresearch and policy research regarding health issues specific to low and middle income countries and healthcare services.

5 International promotion of Japan’s healthcare technology and services
The Bureau contributes to improvements in the standards of public health and medicine by developing health system in target countries
while promoting the growth of healthcare fields in Japan through the sharing of Japan's experience in health system, the transfer ofhealthcare technology and services, and the international expansion of high-quality pharmaceuticals and medical devices from Japan.

Promotion of medical safety at the bedside

Health education for residents

Vaccination guidance for yellow fever

Accepting international trainees fornursing education

Field epidemiological sur vey

Technology transfer for the early
detection of cancer

Seminar on global health for Japanese

Advocating Japan's opinions atinternational conferences

Received the UAE Health Foundation
Prize at the World Health Assembly

Bureau of International Health Cooperation

Bureau of International Health Cooperation

31

Bureau of International
Health Cooperation

4 Research on issues in global health and medicine

32Human Resource
Strategy Center for
Global HealthInstitute for Global
Health Policy Research(iGHP)

1 P h i l o s o p hy o f i G H P

2 Missions of iGHPThe Institute for Global Health Policy Research (iGHP) wasestablished in October 2016 to promote research on global
health policies. Its purpose is to publish Japan's knowledge
a n d a c h i eve m e n t s a s a n "a d v a n c e d h e a l t h c o u n t r y " a n ddevelop related human resources.

• Establish scientific evidence regarding global health policies• Conduct research on health systems, the assessment of
measures, and diplomacy/governance• Develop diverse human resources engaged in the research ofglobal health policies• Propose policies to the Japanese government and to the world

3 St r i v i ng to i m p r ove i n te r n a t i o n a l h e a lt h c a r e p o l i c i e sGroup discussion at a workshop (Osaka site)

Global Health & Medicine

Exterior of iGHP

Of fice room

33

URL:https://hrc-gh.ncgm.go.jp
Human resource registration and search system:
https://hrc-gh-system.ncgm.go.jp/
E-mail: HRC-GH@hosp.ncgm.go.jp

Lecture at a workshop (Tokyo site)

Global Health & Medicine (GHM) is an international,o p e n-a cce s s , p e e r-rev iewe d jo ur nal, p ub lish e d by
the National Center for Global Health and Medicine(NCGM).
Launched at the beginning of the new era (Reiwa) inJapan, the Journal cover s advances in the areas ofclinical sciences, basic sciences, public health, andglobal health. The Journal accepts submissions fromaround the world, and all published ar ticles of GHM
can b e access e d on PubM e d. GHM is de dicate d to
publishing high-quality original research articles that
contribute to advancing global health and medicine,with the goal of creating a global information network
for global health, basic sciences as well as clinicalsciences oriented for clinical application.

Meeting

SeminarBureau of International Health Cooperation

Bureau of International Health Cooperation

To date, research on international healthcare and global health has been
conducted at universities and research institutions in Japan, with fewer researchsites and at smaller scales than in Europe and the United States. Therefore,systematic activities have not been undertaken in Japan for the assessment andresearch of various global health measures from the viewpoints of medicine,
health science, welfare science, epidemiology, sociology, economics, andmedical anthropology. Such activities have also not been conducted for making
policy and diplomacy proposals, or to develop human resources in order toachieve these goals.
The missions of iGHP are to establish scientific evidence for promoting global
health policies, publish such evidence in Japan and globally, make related
policy proposals, and develop human resources. iGHP promotes various
projects through close cooperation among three research departments and incollaboration with related institutions in Japan and around the world.

O n S e p t e m b e r 21 , 2 017, t h e H u m a n R e s o u r c e s S t r a t e g y C e n t e r f o r
Global Health (HRC-GH) started its operation as project entrusted by theInternational Af fairs Division, Minister’s Secretariat, Ministr y of Health,Labour and Welfare, to enhance the presence of Japanese staff members
in international organizations. The missions of HRC-GH are to strategicallye x p a n d Ja p a n’s h u m a n r e s o u r c e s f o r g l o b a l h e a l t h p o li c i e s , e n h a n c etheir abilities through a lifecycle career development approach, and tocontribute to global health agendas. The main activit y of HRC-GH is tocontribute to career development of Japanese human resources for global
health policies and to dispatch them to international organizations. HRCGH has steadily increased the number of Japanese personnel accepted or
promoted at international organizations through providing regular vacancy
information to registrants of the Human Resources Registration and Search
System, conducting individual career consultation ser vices, examination
preparation workshops, and seminars and lectures.

Global Health & Medicine ( journal in English)
Print ISSN : 2434 - 9186 ; Online ISSN : 2434 - 9194

URL: https://www.globalhealthmedicine.com
E-mail: office@globalhealthmedicine.com

34

Developing a strong sense of humanity with global awareness andPioneering a new nursing practice
1 Education
Five functionsof the National
Collegeof Nursing

2 Research
3 Information provision: Library
4 Training: Training Center for Nursing Development
5 Social activities: Open Seminars & International Exchanges

Undergraduate Nursing Course

The National College of Nursing, Japan was launched by the Ministry of Health, Labourand Welfare in 2001. It is an educational institution that trains nursing professionals at the
National Center for Advanced and Specialized Medical Care. Seeking an ideal human carestrategy with heart-to-heart communication, the College trains nurses and midwives who
have clinical abilities for the nursing practice required at the National Center for Advanced
and Specialized Medical Care that is responsible for national policy medicine, along with theabilities required to make contributions to the international community. A key feature ofCollege is that students can learn policy medicine and international medicine at the same time.
The College has contributed to the development of policy medicine nursing and the developmentof advanced practical nurses through the establishment of a first term of research courses(including an education course for nurse specialists) that is equivalent to the graduate school
master's course in 2005, and of a second term that is equivalent to the doctor's course in 2015.

The College is a four-year basic nursing education institution thattrains nurses and midwives. Upon filing an application to the National
Institution for Academic Degrees and Quality Enhancement of Higher
Education, a bachelor's degree for nursing is awarded to graduates.

This course is equivalent to the master’s and doctoral courses, and trains
nurses who have both research abilities and the capabilities of advanced
clinical practice. The course is unique in that is promotes policy medicine
nursing, which is absent at other nursing graduate schools.

Estimated numberof students

400 in Total (100 per grade)

Total numberof students

Master’s course 30 in total (15 per grade)
Doctoral course 9 in total (3 per grade)

Term of education

Four years

Length of program

Prospective
degreeUpon filing an application to the National
Institution for Academic Degrees and Quality
Enhancement of Higher Education, a bachelor's
degree for nursing is awarded to graduates.

Master’s course two years /Doctoral course three years

Prospective
degreeThe students will be awarded a Master ofnursing science, Doctorate of nursing scienceby the National Institute for Academic Degrees
and Quality Enhancement of Higher Education
upon completion of the required program.

Training Center for Nursing
Development
The Center implements a number of courses (including
seminars for exercise instructors and short-term training
concerning nursing research methods and the latest
findings in nursing) for nurses who work at hospitals of
the national centers for advanced, specialized medical
research, the national sanatoriums for Hansen's disease,and the National Hospital Organization.

● Policy-Based Functional Nursing

Graduate
School of
NursingSpecialty
FieldsInternational Nursing / Nursing Education / Nursing
Administration & Informatics

National College of Nursing, Japan

National College of Nursing, Japan

National College ofNursing, Japan

Graduate School of Nursing● Advanced Clinical Nursing
Adult Nursing / Psychiatric & Mental Health Nursing /Maternal & Child Nursing / Gerontological Nursing /Infection Control & Infectious Disease Nursing● Education course for nurse specialists
Cancer nursing / Psychiatric nursing /Pediatric nursing / Infectious disease nursing

Research Center in Clinical Nursing
This center supports clinical nursing researched of National
Center nurses.

NCNJ seeks an ideal human care strategy with heart-to-heart communication.
At t h e C o l l e g e , s t u d e n t s p r i m a r i l y l e a r n h u m a nsciences and interaction studies to obtain the humanunderstanding that forms the basis of nursing in thef irst year. Over four years, they learn specialized
knowledge and skills of nursing while learning abouthuman growth and development and its relationshipwith the environment, and systematically integrate
such knowledge and skills. Through these courses,
we develop the students’ strong sense of humanity,
advanced capabilities for practical nursing and a greaterawareness of the wider world.

Advanced Medical
Service and Nursing

International Nursing
Nursing Science

Human
Development

Interaction

Environment

Understanding of Human Life

Human Science
Understanding of Human Existence

Human Caring

35

36

Access
Center Hospital of the National Center
for Global Health and Medicine/ Research Institute

About the logo markThis symbol represents the pulse of life on earth andour strong wish to maintain health all over the world.

1 - 21 - 1 Toyama, Shinjuku-ku, Tokyo
Postal code: 162 - 8655
Tel: + 81 - 3 - 3202 - 7181

Center Hospital of the National
Center for Global Health andMedicine

Narita Airport

Research InstituteBureau of International Health
Cooperation
Center for Clinical Sciences

KiyoseNerimaSeibu Line

Ikebukuro

Waseda-doriTozai Line

Shinjuku

WasedaFaculty of Letters,
Arts and Sciences,
Waseda University

Fukutoshin Line

Meiji-dori

NCGMmae

Oedo
Line

Wakamatsukawada
JR Sobu Line

Center Hospital/ Research InstituteOkubo-dori

Iidabashi

OtemachiTokyo

For Iidabashi

Statistics Bureau
of Japan
For Shinjuku

Ichikawa

Asakusa Line

Gakushuin
Women's College

For
Kagurazaka

Keisei
Main
Line Kohnodai

Nippori

AccessAccessNishiwaseda

ri
do
aw
Su

Wasedaiza
To ineL

Takadanobaba

Wakamatsu-kawada

Oedo Line

Hamamatsucho
ShinagawaNational College of Nursing, Japan
1 - 2 - 1 Umezono, Kiyose City, Tokyo
Postal code: 204 - 8575

Haneda Airport
For Matsudo

Kohnodai Hospital
Kohnodai Hospital
The Research Centerfor Hepatitis and Immunology

Tel: + 81 - 42 - 495 - 2211
Wayo Women's
University-mae

1 - 7 - 1 Kohnodai, Ichikawa City, Chiba Pref.

Kohnodai
For Narita Airport

Matsudo
Kaido

Koiwa

Ichikawa-mama
Edogawa

Edogawa

Keisei Main Line
Chiba Kaido
Ichikawa

For Chiba
JR Sobu Line37

Kohnodai Hospital of the
National Center for Global
Health and Medicine
Postal code: 272 - 8516
Tel: + 81 - 47 - 372 - 3501

Kohnodai Hospital of the
National Center for Global Health and Medicine
The Research Center for Hepatitis and
Immunology

38