-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAFETY DATA SHEET
Date Updated: 04/03/2022-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 1 > Product and Company Information-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Product Name
DynaMarker dsRNA
Code No.
DM180Company
BioDynamics Laboratory Inc.
Address
9-7 Hongo 2-Chome, Bunkyo-Ku, Tokyo 113-0033 JAPANPhone+81-3-5803-9983
Fax+81-3-5684-6270-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------<2 > Hazards Identification-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHS Classification:
Classification not possible
Symbol: None
Signal word: None
Hazard statement(s): None
Precautionary statement(s): None
Supplemental Hazard Statements: None-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------<3 > Composition/Information on Ingredients-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Component:
DynaMarker dsRNAThe product contains no substances which at their given concentration, are considered to be hazardous to health. We recommend
handling all chemicals with caution.
Hazardous Ingredient(s) : None-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 4 > First Aid Measures-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Description of first aid measures
General advice:Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled:
Not expected to be an inhalation hazard under anticipated conditions of normal use of this material.
Consult a physician if necessary.
In case of skin contact: Wash off with soap and plenty of water. Consult a physician.
In case of eye contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed:
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Most important symptoms and effects, both acute and delayed
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Indication of any immediate medical attention and special treatment needed
No data available-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 5 > Fire Fighting Measures-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Extinguishing media
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture:
No data available
Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Further information:
No data available- 1 ver. 1.1

-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 6 > Accidental Release Measures-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Personal precautions, protective equipment and emergency procedures:
Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation.
Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into theenvironment must be avoided.
Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed
containers for disposal.
Reference to other sections: For disposal see section 13.
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 7 > Handling and Storage-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Precautions for safe handling:
Avoid contact with skin and eyes. Avoid inhalation of vapor or mist.
Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be
carefully resealed and kept upright to prevent leakage.
Recommended storage temperature:- 80 °C
Specific end use(s):No data available-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 8 > Exposure Controls / PPE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Engineering controls
Ensure adequate ventilation, especially in confined areas
Personal Protective Equipment
Respiratory:
In case of insufficient ventilation wear respirators and components tested and approved underappropriate government standards.
Hand:
Compatible chemical-resistant gloves.
Eye:
Chemical safety goggles.
General Hygiene Measures
Wash contaminated clothing before reuse. Wash thoroughly after handling.
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 9 > Physical/Chemical Properties-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Appearance Form:liquid, clear
Colour: colourless
Odor:
N/A
Odor Threshold:
N/A
pH:
N/A
Melting point/freezing point:
N/A
Initial boiling point and boiling range:
N/A
Flash point:
N/A
Evaporation rate:
N/A
Flammability (solid, gas):
N/A
Upper/lower flammability or explosive limits: N/A
Vapour pressure:
N/A
Vapour density:
N/A
Relative density:
N/A
Water solubility:
N/A
Partition coefficient (n-octanol/water):
N/A
Auto-ignition temperature:
N/A
Decomposition temperature:
N/A
Viscosity:
N/A
Explosive properties:
N/A
N/A = not available- 2 ver. 1.1

-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 10 > Stability and Reactivity-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Stability: Stable under normal conditions.
Materials to Avoid: No dangerous reaction known under conditions of normal use.
Hazardous Decomposition Products: None under normal use.
Hazardous Polymerization: No data available-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 11 > Toxicological Information-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Information on toxicological effects
Acute toxicity:
No data available.
Skin corrosion/irritation:
May cause skin irritation in susceptible person.
Serious eye damage/eye irritation:
May cause eye irritation with susceptible person.
Respiratory/ Skin sensitization:
Respiratory sensitization: No data available.
Skin sensitization: No data available.
Germ cell mutagenicity:
No data available.
Carcinogenicity:
No data available.
Reproductive toxicity:
No data available.
Specific target organ toxicity - Single exposure: No data available.
Specific target organ toxicity - Repeated exposure: No data available.
Aspiration hazard:
No data available.
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 12 > Ecological Information-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Hazardous to the aquatic environment(Acute):No data available.
(Long-term):
No data available.
Hazardous to the ozone layer:
No data available.
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 13 > Disposal Considerations-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Appropriate method of disposal of substance or preparation.
Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 14 > Transport Information-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------UN number:
ADR/RID: - IMDG: - IATA-DGR: UN proper shipping name:
ADR/RID: - IMDG: - IATA-DGR: Transport hazard class(es):ADR/RID: - IMDG: - IATA-DGR: Packaging group:
ADR/RID: - IMDG: - IATA-DGR: Environmental hazards:
ADR/RID: - IMDG: - IATA-DGR: Special precautions for user:
No data available-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 15 > Regulatory Information-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Law concerning Pollutant Release
and Transfer Register / PRTR Law:
Industrial Safety and Health Law:
Chemical Substances Control Law:
Fire Service Law:
Poisonous and Deleterious Substances Control Law:

Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
- 3 ver. 1.1

-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 16 > Reference-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1) Japan CHEmicals Collaborative Knowledge database2) NITE Chemical Risk Information Platform)
3) UNECE web page (GHS pictograms)-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------< 17 > Other Information-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our knowledge and is applicable to the product with regard toappropriate safety precautions. It does not represent any guarantee of the properties of the product. Biodynamics Laboratory Inc.,
shall not be held liable for any damage resulting from handling or from contact with the above product.

- 4 ver. 1.1