Wieland B. Huttner
Name:Date of birth:

Wieland Bernhard HUTTNER
15 February 1950 in Hanover, Germany

Research topics
1. Cell Biology, Neurobiology, Developmental Neurobiology;
2. Neural stem cells, mammalian neurogenesis, evolution of the neocortex
Link to research group homepage:
http://www.mpi-cbg.de/research/research-groups/wieland-huttner.html

University Studies
1969 - 1975
Study of medicine, University of Hamburg, Germany and Oxford, UK1972 - 1976
Doctoral thesis in Physiological Chemistry, University of Hamburg, Germany
Doctoral Thesis: "The permissive action of glucocorticoids on the cyclic AMP-mediatedinduction of phosphoenolpyruvate carboxykinase in rat liver"; Institute of PhysiologicalChemistry, University of Hamburg;1975 - 1976
Internship, University of Hamburg, Germany
1976“Approbation”, Licence to practice medicine
1985
Habilitation in Physiological Chemistry, University of Würzburg, Germany"Molecular cell regulation by post-translational modifications: studies on thephosphorylation and tyrosine sulfation of proteins"
Positions1976 – 1977
1977 – 1980

Postdoc, MPI for Experimental Medicine, Göttingen, Germany
Postdoc with Paul Greengard (Nobel Laureate 2000), Department of Pharmacology, YaleUniversity, New Haven, USA1981 – 1985
Junior Group Leader, MPI for Psychiatry, Munich, Germany
1985 – 1990
Group Leader, EMBL Cell Biology Programme, Heidelberg, Germany
1987 - 1991: Dean of Graduate Studies, EMBL PhD Programme, Heidelberg, Germany
1991 - 2000: Professor of Neurobiology and Chair, Institute of Neurobiology,
University of Heidelberg, Germany
1991 - 1999: Speaker, SFB 317 Molecular Biology of Neural Mechanisms and Interactions
University of Heidelberg, Germany
1992 - 2000: Speaker, “Graduiertenkolleg“ Molecular and Cellular Neurobiology
University of Heidelberg, Germany
1998 - present: Director, MPI of Molecular Cell Biology and Genetics, Dresden, Germany
2001 - present: Speaker, International Max Planck Research School
IMPRS-CellDevoSys, Dresden, Germany
2002 - present: Honorary Professor of Neurobiology, Technische Universität Dresden, Germany
2004 - 2010: Member of the German Council of Science and Humanities ("Wissenschaftsrat")
2009 - 2012: Chair of the Scientific Council of the Max Planck Society

Funding:Awards:DFG; ERC Advanced Grant
Karl-Winnacker-Award (1985)
Member of EMBO (since 1988)
Member of the German National Academy of Sciences Leopoldina (“Deutsche Akademieder Naturforscher Leopoldina”) (since 2002)
Berthold Medal, German Society for Endocrinology (2003)

List of 10 most important publications in the last 3 years:
2015
Florio, Marta; Albert, Mareike; Taverna, Elena; Namba, Takashi; Brandl, Holger; Lewitus, Eric; Haffner,Christiane; Sykes, Alex; Wong, Fong Kuan; Peters, Jula; Guhr, E.; Klemroth, Sylvia; Prüfer, Kay; Kelso,Janet; Naumann, Ronald; Nüsslein, Ina; Dahl, Andreas; Lachmann, Robert; Pääbo, Svante; Huttner,Wieland B.
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion.
Science (2015) March 27, Vol. 347, p. 1465-70
2014
Lewitus, Eric; Kelava, Iva; Kalinka, Alex T.; Tomancak, Pavel; Huttner, Wieland B.
An Adaptive Threshold in Mammalian Neocortical Evolution.
PLoS Biol. (2014) November 18, 12(11): e1002000. doi:10.1371/journal.pbio.1002000
Taverna, Elena; Götz, Magdalena; Huttner, Wieland B.
The cell biology of neurogenesis: toward an understanding of the development and evolution of theneocortex.
Annu. Rev. Cell Dev. Biol. (2014), June 27, Vol. 30, p. 465-502
Mora-Bermúdez, Felipe; Matsuzaki, Fumio; Huttner, Wieland B.
Specific polar subpopulations of astral microtubules control spindle orientation and symmetric neural stem
cell division.
Elife, (2014) July 4, 3:eLife.02875.
Florio, Marta; Huttner, Wieland B.
Neural progenitors, neurogenesis and the evolution of the neocortex.
Development (2014), Vol. 141, no. 11, p. 2182-2194
Fei, Jifeng; Haffner, Christiane; Huttner, Wieland B.
3' UTR-Dependent, miR-92-Mediated Restriction of Tis21 Expression Maintains Asymmetric Neural Stem
Cell Division to Ensure Proper Neocortex Size.
Cell Rep. (2014), April 24, Vol. 7, no. 2, p. 398-411
Stenzel, Denise; Wilsch-Bräuninger, Michaela; Wong, Fong Kuan; Heuer, Heike; Huttner, Wieland B.
Integrin αvβ3 and thyroid hormones promote expansion of progenitors in embryonic neocortex.
Development (2014), Vol. 141, no. 4, p. 795-806
2013
Paridaen, Judith; Wilsch-Bräuninger, Michaela; Huttner, Wieland B.
Asymmetric inheritance of centrosome-associated primary cilium membrane directs ciliogenesis after cell
division.
Cell (2013), Vol. 155, no. 2, p. 333-344,
Lewitus, Eric; Kelava, Iva; Huttner, Wieland B.
Conical expansion of the outer subventricular zone and the role of neocortical folding in evolution anddevelopment
Front. Hum. Neurosci. (2013), August 1, Vol. 7:424
Sykes AM, Huttner WB.
Prominin-1 (CD133) and the Cell Biology of Neural Progenitors and Their Progeny
Adv Exp Med Biol. (2013), Vol. 777, p. 89-98