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Dess-Martin periodinane    !"$!" !" →Sir Derek Barton
Nobel Prize
1969

Pure Appl. Chem. 1987, 59, 937.

  (1,2,11,12  )Victor Grignard
Nobel Prize
1912

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→Cl1Mg41' *-:9,%8→LiCl2ArX+Mg→ArMgX16
Angew. Chem. Int. Ed. 2008, 47, 6802-6806.

Prof. Paul Knochel
The first report for turbo-Grignard reagent: Ren, H.; Krasovskiy, A.; Knochel, P., Org. Lett. 2004, 6, 4215-4217.
reviews: (a) P. Knochel, A. Gavryushin, K. Brade, "Functionalized organomagnesium compounds: Synthesis and reactivity" in The
Chemistry of Organomagnesium Compounds, eds. Z. Rappoport, I. Marek, John Wiley & Sons, Chichester, 2008, p511.
(b) Ila, H.; Baron, O.; Wagner, A. J.; Knochel, P., Chem. Commun. 2006, 583-593.

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5@9(2 :@J . Am. Chem. Soc. 1986, 108, 2102-2103.

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J . Am. Chem. Soc. 2007, 129, 10974-10975.



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Reich: http://www.chem.wisc.edu/areas/reich/pkatable/
Williams: http://research.chem.psu.edu/brpgroup/pKa_compilation.pdf( 5<FI@2+%&
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ortho-metalation (FUL$ )

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Herbert C. Brown
Nobel Prize 1979

R = MeScience 2012, 335, 567-570.

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6Ne`^_K$!*#M #)'N%=42RRA(M<U62WOrganometallics: A Concise Introduction
C. Elschenbroich, A. Salzer, Wiley-VCH, 1992

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*OSNMR76@+:)/ecg@JACS 1985, 107, 1810.

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JACS 1993, 115, 11016.

Lithium Chemistry: A Theoreticaland Experimental Overview
Eds by A.-M. Sapse, P. V. R.
Schleyer; Wiley-Interscience, 1995

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Schlenk+Wilhelm
Schlenk

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Schlenk+@',Et2MgD*9<2( LQN

ACIEE 1984, 23, 534.

MgBr2
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J. Organomet. Chem. 1990, 393, 315.

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Kontes, ChemGlass, Aldrich[ZXO G9N*U]W`]F/:
The manipulation of air-sensitive compounds 2nd Ed.
D.F. Shriver, M.A. Drezdzon, Wiley-Interscience, ISBN: 047186773X
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