Aeris
The future is compact

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On a journey together
Modern X-ray diffraction
Across academia, more and more researchers are
joining the race to push scientific frontiers. In industry,
speed-to-market is essential for getting ahead.
Meanwhile, regulations are tightening when it comesto pharmaceuticals, food, or environment. Whatever
your organization’s challenges, efficient and compliant
solutions give you the confidence to face them.

At Malvern Panalytical, we listen to you and create
solutions based on your needs. Your input informs our
output. In partnership with our colleagues and customers
like you, we’ve created a modern compact XRD solution
to help you succeed.

Maximize efficiency withspeed and accuracy
Aeris combines easy external sample handling with clear,simple, push-button operation. Thoughtfully designed
using the highest-quality components, Aeris provides
speed and data quality at a reduced power setting. This
costs less for both you and the planet. Combining an
onboard computer and a classic goniometer, Aeris’ highperformance components and precision sample stages
can perform a full scan in less than five minutes.

Simplify your workflow
With Aeris, you can either introduce samples manually or
via fully integrated automated systems. Sample holders
are easily and precisely handled via external positioning
stations and can be changed without disturbing any
ongoing measurements. With Aeris, not everyone needs
XRD expertise. Multilevel user accounts and preprogrammed methods and analyses combine with aneasy-to-use touchscreen to ensure that great results areaccessible to all.

Meet Aeris: future-proof, compact X-ray diffraction
How can you best optimize your materials and qualify
your product? X-ray powder diffraction is a wellestablished, non-destructive way of getting to the heartof crystalline materials and finding the answers you need.
Building on over 70 years of experience, we’re proud topresent Aeris – our super-compact, fully capable X-ray

powder diffractometer. With its economy and flexibility
in measurement and automation, it’s sure to provide
the right solutions for you. Aeris provides a simplified,customized and integrated workflow whilst offering theopportunity for configuration changes and upgrades
should your requirements evolve in the future.

Want to know more?
Take a closer look…

Flexibility to obtain the best data for you
Aeris offers a range of measurement configurations so
you can achieve the best possible powder diffraction
data for your sample type:• Bragg-Brentano reflection powder diffraction• Transmission diffraction• Grazing incidence diffraction• Small spot diffraction• 2D diffraction• Microdiffraction• Non-ambient measurements• In-situ measurements

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5... and more indepth insights

Reflection

Identify potential hazards in mineral mixtures...
Yobs
Ycalc
Yobs-Ycalc

200000100000

0
20

30

40

50

60

70

80

90

100 110120 130

Position [°2θ] (Copper (Cu))

Low detection limits help to make sure you’re complying withenvironmental regulations. And Aeris can reliably quantify
even a few micrograms of hazardous substances – suchas respirable silica, asbestos, and rutile – in minimal time.
This figure shows part of a 20-minute reflection scan of a
polyvinyl chloride filter with 0.0047mg of quartz, the mostcommon polymorph of respirable silica. The quantification
limit determined from the peak-to-noise ratio for the scanis 0.0036mg. Aeris can push the quantification limit below
0.005mg in less than 10 minutes.

quartz8000

Intensity (counts)

Combining low noise, high resolution, and true
reproducibility, Bragg-Brentano results reveal new
insights into your materials’ structure-property
relationships. This data can take you all the way fromphase identification to crystal structure solution.

Counts/s

Higher-quality powder data

7500

7000

6500

Rietveld refinement of synthesized and heat-treated
AgCaVO4 , Ref: G. Nénert, Z. Kristallogr. 2017; 232(10)

26.1

26.2

26.3 26.4 26.5

26.6 26.7

26.8 26.9 27.0

27.1

27.2

27.3 27.4
2Theta (°)

Transmission measurements let you minimize preferredorientation effects. They are an especially great matchfor low-absorbing organic materials in the pharmaceuticalindustry.
A true innovation in transmission measurement mode isachieved by incorporating a beam stop to maximize thespeed provided by the full width of the strip detectors.
This results in an unmatched low-angle performancefor transmission measurements, with exceptionally low
background and remarkably high speed.

Counts160000Indomethacin 5%
a-Lactose monohydrate 94.1%
b-Lactose 1.1%
Indomethacin 4.8%

90000

40000

10000

0

10

20

40

30

50

Position [°2ѳ] (Copper (Cu))…reduce contamination in pharmaceuticals...
When you’re working with pharmaceutical formulations, it’s
essential to pick up on potential polymorph contamination.
Aeris’ high sensitivity enables you to do just that, improving
your product quality and preventing unnecessary risks.
This figure shows two reflection scans revealing 0.5%α-Indomethacin contamination in a drug formulation. With its
low background and high resolution, Aeris lets you routinely
screen your materials for low level impurities.

Intensity (counts)

Transmission

200000150000α-Indomethacin
100000Transmission XRD measurements and quantitative
analysis of an Indomethacin formulation prepared
between mylar foils.

50000

High quality drug formulation
Contaminated drug formulation: 0.5% impurity
0
7.5

With grazing incidence X-ray diffraction, you can
now explore your samples’ surfaces. The result? Bettermeasurement of crystallographic properties in thin films
and coatings.

Counts
6000

Perovskite on glass_Aeris_GIXRD_omega=0.5 deg
MAPbBr3

4000

2000

0

20

30

40

50

60

70

Position [°2θ] (Copper (Cu))

8.5

9.0

2Theta (°)…or identify the best process for your advanced materials
To refine your processing parameters, you need to analyze
them quickly. With Aeris, even five-minute scans can
immediately show whether a processing parameter isaffecting crystalline phase purity. This figure shows two
five-minute measurements of two metal-organic framework(MOF) samples in reflection mode, each processed under
different conditions. Using Aeris, you can rapidly optimize
these processing parameters for the best quality material –every time.

5 Minute scans
MOF CAU-10H synthesis 1

Intensity (counts)

Grazing Incidence

8.0

MOF CAU-10H synthesis 2

2500

2000

1500

1000

500

A 36 min GIXRD measurement of a MAPbBr3 Perovskite
layer deposited on a glass substrate.

0

7

8

9

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18
2Theta (°)

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Automate your future
Aeris gives you a full range of upgradeable handling
options to place your sample on its external sample
platform. So, it’s easy to start small and scale up. Aeris isalso designed to integrate fully into your own automatedenvironments. If you need support incorporating it into
your LIMS system, our expert group will be happy to help.

Choose from:• Manual sample platform with a single position for the
sample loader• Integrated 6-position sample changer with automatic
external sample handling• A connection for belt automation (operated via
UAI interface)• Bespoke automation solutions with large-capacity
sample handling• Full integration into multi-system automated labs

Easy and precise loading
for all sample types
We all know how important accurate sample handling is,but the right sample holder is equally essential. Correct
loading is easy for all Aeris users – every single time.
Precision-built sample holders can accommodate a wide
range of sample types, including powders, solids, liquids,

or slurries. Their quantities can range from standardsized pressed pellets to milligrams. And if you’ve got
air-sensitive or potent samples, we’ve got sealed holders
for those too. Whatever your application may be, we canhelp you find the right holder – so, let’s talk!

It’s your lab – do it your way

Get instant results
Aeris’ reliable onboard RoboRiet software makes analysis
faster for the experts, easier for non-experts and saves
time for everyone. RoboRiet automates the entire
measure-analyse-report sequence, providing rapid
quantitative-phase analysis by means of Rietveld refinement.
With Aeris’ easy-clean touchscreen, you have instant accessto instrument status, live measurement progress, andanalytical results. What’s more, our expert team can also
develop operating procedures for you – from touch-screen
setup and sample preparation advice to method setup,
automated analysis, and reporting formats.

Ready for industry, flexible for research
Aeris doesn’t compromise on compatibility. Its XRDML data
files are compatible with all our industry-leading analyticalsoftware solutions – including HighScore, HighScore Plus,
Stress, and Industry. It supports straight-line calibration for
rapid quality control and is fully compatible with LIMS systems.
In other words, you’ll have access to a full suite of analysis
capabilities, including:• Phase identification• Phase quantification• Crystal structure refinement• Crystallinity• Size, strain, and stress analysis• Statistical clustering• Calibration line-based quantification methods• …and more89

Test the boundaries
You’ve found a materials system that fits yourrequirements, but how can you be sure of the range ofconditions it can operate in before unwanted changes
occur? With Aeris, you can investigate a range ofmaterial variants to see how processing, environmental,
and compositional changes affect performance. The
HighScore Suite is designed to process, analyze, anddisplay large data sets, and this software enables you to
identify and optimize key stages in your processes andunique properties in your materials.
At the same time, an integrated non-ambient stage
gives you the tools to model your material’s robustness
in tough operating conditions. Talk to us about options
for your research! We can provide bespoke multipurpose
stages for unusual samples, chambers for non-ambientconditions, electrochemical cells, and more.

Extend your vision

Simple 2D diffraction measurements are the ideal way
to visualize your material and plan further investigations.
They also provide better peak shapes for low angle
data, and are a great choice for MOFs, clays, andpharmaceuticals. With Aeris 2D, incorporating our highresolution PiXcel3D detector, you can easily perform
such 2D measurements. You’ll instantly see whether yourmicrostructure is a problem, whether your crystallites are
smaller or larger, and whether they have a random or apreferred orientation.

Look out for our new microdiffraction optic that expands
your 2D capability further! This proprietary solution,
combined with 2D data collection, enables you tocollect position-sensitive data across your sample plus
simultaneously collect multiple XRD data sets across aheterogenous sample.

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21 CFR Part 11 compliance built in

Step into the future

From instrument qualification to compliance and auditing,
we understand how important data integrity is – andwe’re here to help you minimize risk. Our OmniTrust
solution supports working in regulated environments on
multiple analytical instruments, including Aeris. Designed
in collaboration with industry experts, OmniTrust ensures
record accuracy and best practices in data integrity.
How? By providing tools to define user roles suitable forWith Aeris, you’ll have state-of-the-art X-ray powder
diffraction data – whatever the type of polycrystalline
sample you have. You’ll have peace of mind in thelab, thanks to a unique internal interlocked enclosure
providing complete radiation protection. External loading
will protect components from tampering, spillage, or
accidents across the entire optical path. With different
user interfaces designed for entry-level or advanced
users, even users with minimal training can contribute.
A true uncoupled theta-2theta goniometer will keep
samples horizontal, ensuring flexibility and top-quality
measurements. By providing the data quality of a floorstanding system in a compact instrument, Aeris will
deliver unrivalled cost savings. And you can do all this at
the push of a button.

individual companies’ workflows, as well as by trailingeach step of a user’s interaction with Aeris: from thecreation of measurement routines up to the review ofdata analysis. Its system controls help prevent user errors
and ensure data integrity, enabling you to comply with all
relevant regulations. And if there is a potential integrity
issue, the information is at your fingertips thanks to
OmniTrust. You can save time and say goodbye to stress.

Traceability and control
at your fingertips

So, what are
you waiting for?
With the options available, why not put them together tomake a unique instrument for your unique requirements?
A Malvern Panalytical diffractometer is built for you sothat you get the right data, just how you need it.

Talk to us today!

We draw on the power of our analytical instruments
and services to make the invisible visible and theimpossible possible.
Through the chemical, physical and structural analysis
of materials, our high precision analytical systems andtop-notch services support our customers in creating abetter world. We help them improve everything from theenergies that power us and the materials we build with,to the medicines that cure us and the foods we enjoy.
We partner with many of the world’s biggest companies,
universities and research organizations. They value us
not only for the power of our solutions, but also for thedepth of our expertise, collaboration and integrity.
We are committed to Net Zero in our own operations
by 2030 and in our total value chain by 2040. This is
woven into the fabric of our business, and we help our
employees and customers think about their part increating a healthier, cleaner, and more productive world.

Service & Support
Malvern Panalytical provides the global training, service
and support you need to continuously drive youranalytical processes at the highest level. We help you
increase the return on your investment with us, andensure that as your laboratory and analytical needs
grow, we are there to support you.
Our worldwide team of specialists adds value to yourbusiness processes by ensuring applications expertise,
rapid response and maximum instrument uptime.
• Local and remote support• Full and flexible range of support agreements• Compliance and validation support• Onsite or classroom-based training courses• e-Learning training courses and web seminars• Sample and application consultancy

With over 2300 employees, we serve the world, and weare part of Spectris plc, the world-leading precision
measurement group.

Malvern Panalytical. We’re BIG on small™

Malvern Panalyticalwww.malvernpanalytical.com

Grovewood Road, Malvern,
Worcestershire, WR14 1XZ,
United Kingdom

Lelyweg 1,7602 EA Almelo,
The Netherlands

Tel. +44 1684 892456
Fax. +44 1684 892789

Tel. +31 546 534 444
Fax. +31 546 534 598

Disclaimer: Although diligent care has been used to ensure that the information in this material is accurate, nothing herein can be construed to imply any representation or warranty as to the accuracy, correctness or completenessof this information and we shall not be liable for errors contained herein or for damages in connection with the use of this material. Malvern Panalytical reserves the right to change the content in this material at any time without notice.
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