PRODUCTLISTTHE QUALITY
PHARMACEUTICALHEALTH - FOOD

Indena’s Active Pharmaceutical Ingredients are produced incompliance with cGMPs and in pharmaceutical inspected
plants, supported by CTD-DMFs.
Indena’s ingredients for food supplements are produced
under Hazard Analysis and Crytical Control Points (HACCP)
and in compliance with Food Safety Modernization Act (FSMA)

E
C

HALAL
certified
ECOCERT
validated
CEP
grantedKOSHER
certifiedCo
G

COSMOS
validated

GRAS: the product can be used as
an ingredient in common food (US)OUR MISSIONAt Indena we believe that an in-depth knowledgein active ingredients derived from botanicals
and the search for excellence at all times are
crucial commitments to serving our customers inpharmaceuticals, and healthfoods.
Research and production technologies are themain focus of our mission and the way we create a“value difference” for our partners.
And we’ve got 100 years of experience to prove it.

Please note this documentation is available for various Countries all over the worldand hence it may contain statements or product classification not applicable toyour Country. The claims made are in reference to ingredients only, hence they
do not refer to finished products and they may not comply with Regulation EC n.
1924/2006 or other provisions in place in your Country. These statements havenot been evaluated by the Food and Drug Administration. These products are notintended to diagnose, treat, cure or prevent any disease. Marketers of any finishedproduct containing any ingredient are responsible for ensuring compliance with allapplicable laws and regulations of Countries where the finished product is sold.

The ingredients described herein are offered for consideration for use in healthfood, common food and pharmaceuticals.

Excellence in botanical derivatives

06 ISOLATED or SEMISYNTHETIC
PURE PRODUCTS

PURE MOLECULES ISOLATED OR DERIVED FROM PLANTS

10 STANDARDIZED, PURIFIEDor OTHER CHARACTERIZEDDRY EXTRACTS
DRY EXTRACTS WITH REPRODUCIBLE CONTENT OF CHARACTERISTIC CONSTITUENTS

INDENARESEARCHES,DEVELOPS and
MARKETSACTIVE
PRINCIPLES
and INGREDIENTSDERIVED FROMMEDICINAL
and EDIBLE
PLANTS

22 CHARACTERIZED, STANDARDIZEDOILY and SOFT EXTRACTSOILY / SOFT EXTRACTS WITH REPRODUCIBLE CONTENT OF CHARACTERISTIC CONSTITUENTS

24 PHYTOSOME®

ISOLATED or SEMISYNTHETIC
PURE PRODUCTS

PURE MOLECULES ISOLATED OR DERIVED FROM PLANTS

BRAND - ENGLISH NAMEBOTANICAL ORIGINASSAYBIOLOGICAL ACTIVITYBOLDINE

Peumus boldus Molina - Bark of the trunk≥98.5% ≤100.5% by potentiometry

Choleretic

CABAZITAXEL

Taxus baccata L. - Twig and leaf

≥97.5% ≤102.0% by HPLC

Antimitotic / Anticancer

Gloriosa superba L. - Seed

≥97.0% ≤102.0% by potentiometry

Antigout

COLCHICINE USP

Gloriosa superba L. - Seed

≥94.0% ≤101.0% by HPLC

Antigout

COLCHICINE MICRONIZEDGloriosa superba L. - Seed

≥94.0% ≤101.0% by HPLC

Antigout

CBD (NATURAL)

Cannabis sativa L. - Leaf, twig and inflorescence≥98.0% ≤102.0% by HPLC-

COLCHICOSIDE

Gloriosa superba L. - Seed≥85.0% by HPLC

Chemical intermediate

10-DEACETYLBACCATIN III

Taxus baccata L. - Twig and leaf

≥96.0% by HPLC

Chemical intermediate

DOCETAXEL

Taxus baccata L. - Twig and leaf

≥97.% ≤102.0% by HPLC

Antimitotic / Anticancer

DOCETAXEL TRIHYDRATE

Taxus baccata L. - Twig and leaf

≥97.5% ≤102.0% by HPLC

Antimitotic / Anticancer

18β-GLYCYRRHETINIC ACID
- ENOXOLONE EUR. PH.

Glycyrrhiza glabra L.- Root

≥98.0% ≤101.0% by acidimetry

Anti-inflammatory

COLCHICINE PH. EUR.

CGALANTHAMINE BROMIDRATEC

Narcissus pseudonarcissus L. - Bulb

≥99.0% ≤101.0% by potentiometry

Antialzheimer

PACLITAXEL (NATURAL)

C

Taxus x media Rehder - Leaf and twig

≥98.0% ≤ 102.0% by HPLC

Antimitotic / Anticancer

PACLITAXEL (SEMISYNTHETIC)C

Taxus baccata L. - Leaf and twig

≥97.0% ≤102.0% by HPLC

Antimitotic / Anticancer

PHARMACEUTICAL

Indena’s Active Pharmaceutical Ingredients are produced incompliance with cGMPs and in pharmaceutical inspected
plants, supported by CTD-DMFs.

HEALTH - FOOD

Indena’s ingredients for food supplements are produced
under Hazard Analysis and Crytical Control Points (HACCP)
in authorized areas.

6

HALAL
certified

E
C

ECOCERT
validated
CEP
grantedKOSHER
certified

Co
G

PACKAGING MATERIALS :: Foodgrade polyethylene bags, multilayerbags :: Kraft type cardboard drums,
metallic drums, polyethylene drums,
polypropylene pails (UN approved
drums are used for hazardous products)

COSMOS
validated

GRAS: the product can be used as
an ingredient in common food (US)7

ISOLATED or SEMISYNTHETIC
PURE PRODUCTS

PURE MOLECULES ISOLATED OR DERIVED FROM PLANTS(continue)
BRAND - ENGLISH NAMEBOTANICAL ORIGINASSAYBIOLOGICAL ACTIVITY

RESERPINE

Rauvolfia vomitoria Afz. - Root bark≥99.0% ≤101.0% by potentiometry

Antihypertensive

RESERPINE USP

Rauvolfia vomitoria Afz. - Root bark≥97.0% ≤101.0% by HPLC

Antihypertensive

RESERPINE MICRONIZED

Rauvolfia vomitoria Afz. - Root bark≥99.0% ≤101.0% by potentiometry

Antihypertensive

THIOCOLCHICOSIDE (crystallized from water)

Gloriosa superba L. - Seed

≥96.0% ≤102.0% by HPLC

Muscle relaxant

THIOCOLCHICOSIDE (crystallized from EtOH)

Gloriosa superba L. - Seed

≥97.0% ≤102.0% by HPLC

Muscle relaxant

PHARMACEUTICAL

Indena’s Active Pharmaceutical Ingredients are produced incompliance with cGMPs and in pharmaceutical inspected
plants, supported by CTD-DMFs.

HEALTH - FOOD

Indena’s ingredients for food supplements are produced
under Hazard Analysis and Crytical Control Points (HACCP)
in authorized areas.

8

HALAL
certified

E
C

ECOCERT
validated
CEP
grantedKOSHER
certified

Co
G

PACKAGING MATERIALS :: Foodgrade polyethylene bags, multilayerbags :: Kraft type cardboard drums,
metallic drums, polyethylene drums,
polypropylene pails (UN approved
drums are used for hazardous products)

COSMOS
validated

GRAS: the product can be used as
an ingredient in common food (US)9

STANDARDIZED, PURIFIED or OTHER
CHARACTERIZED DRY EXTRACTS
DRY EXTRACTS WITH REPRODUCIBLE CONTENTOF CHARACTERISTIC CONSTITUENTS
BRAND - ENGLISH NAMEBOTANICAL ORIGINASSAYBIOLOGICAL ACTIVITY

ARTICHOKEHK

Cynara cardunculus L. - Leaf

≥6.0 ≤12.0% of caffeoylquinic acids by HPLC

Cholesterol and Intestinal health

ARTICHOKE

K

Cynara cardunculus L. - Leaf

≥1.1 of chlorogenic acid by HPLC

Cholesterol and Intestinal health

ARTICHOKE

H

Cynara scolymus L. - Leaf

≥2.5% of chlorogenic acids, ≥6.0% of Caffeoylquinic acids, 1.5% of total
flavonoids by HPLC

Cholesterol and Intestinal health

BILEAR - ARTICHOKE

CH

Cynara cardunculus L. - Leaf

≥0.3% flavonoids expressed as luteolin-7-O-glucoside,≥2.5% caffeoylquinic acid expressed as chlorogenic acid,≥0.6% chlorogenic acid by HPLC

Cholesterol and Intestinal health

PYCRINIL® - ARTICHOKE

H

Cynara cardunculus L. - Leaf

≥20.0% of Caffeoylquinic acids, ≥5.0% of total flavonoids, ≥5.0% of
cynaropicrin by HPLC-

PRODIGEST®
ARTICHOKE AND GINGER

Cynara cardunculus L. - Leaf
Zingiber officinale Roscoe - Rhizome

Artichoke extract: ≥28.1 ≤34.4% by HPLC
Ginger extract: ≥6.2% ≤7.6% by HPLC

Gut/Digestive health

BEANBLOCK® - BEAN

Phaseolus vulgaris L. - Seed

≥6.0% as alpha amylase inhibitor by HPLC; ≥ 1,100 U/mg of alphaamylase inhibiting activity; ≤ 30,000 HAU/g of hemagglutinating activity

Appetite regulator,
Healthy blood sugar metabolism®

MIRTOSELECT® - BILBERRY

HK

Vaccinium myrtillus L. - Fresh frozen fruit≥36.0% of anthocyanins, ≤ 1% anthocyanidins by HPLC

Eye health, Capillarotropic,
Antioxidant activity

MYRTOCYAN® - BILBERRY

C

Vaccinium myrtillus L. - Fresh frozen fruit≥32.4% ≤39.6% of anthocyanins, ≤ 1% anthocyanidins by HPLC

Venous insufficiency and capillar fragility

BLACK COHOSH

K

Cimicifuga racemosa (L.) Nutt. (syn. Actaea racemosa L.)
Rhizome and root

≥5% of total triterpenic glycosides

Menopause

BOLDO

K

Peumus boldus L. - Leaf and bark≥0.05% of boldin by TLC; ≤0.2% of total alkaloids by acidometry

Choleretic agent, digestive health

BUTCHER’S BROOM

K

Ruscus aculeatus L. - Rhizome and root

≥9.0% ≤11.0% of saponins calculated as ruscogeninsby spectrophotometry

Vasoprotectant, Capillarotropic

CASCARA SAGRADA

K

Rhamnus purshiana DC. - Bark of the trunk≥20.0% ≤25.0% of cascarosides expressed as cascaroside A
by spectrophotometry

Laxative, Gut health

CALIFORNIAN POPPY

HK

Eschscholtzia californica Cham. - Flowering herb

0.4% of alkaloids as californidine by spectrophotometry

Mood, Quality sleep

PHARMACEUTICAL

Indena’s Active Pharmaceutical Ingredients are produced incompliance with cGMPs and in pharmaceutical inspected
plants, supported by CTD-DMFs.

HEALTH - FOOD

Indena’s ingredients for food supplements are produced
under Hazard Analysis and Crytical Control Points (HACCP)
in authorized areas.

10

HALAL
certified

E
C

ECOCERT
validated
CEP
grantedKOSHER
certified

Co
G

PACKAGING MATERIALS :: Foodgrade polyethylene bags, multilayerbags :: Kraft type cardboard drums,
metallic drums, polyethylene drums,
polypropylene pails (UN approved
drums are used for hazardous products)

COSMOS
validated

GRAS: the product can be used as
an ingredient in common food (US)11

STANDARDIZED, PURIFIED or OTHER
CHARACTERIZED DRY EXTRACTS
DRY EXTRACTS WITH REPRODUCIBLE CONTENTOF CHARACTERISTIC CONSTITUENTS(continue)
BRAND - ENGLISH NAMEBOTANICAL ORIGINASSAYBIOLOGICAL ACTIVITY

CENTELLA ASIATICA
SELECTED TRITERPENES

Centella asiatica (L.) Urban - Leaf

≥36.0% ≤44.0% of asiaticoside, ≥56.0% ≤64.0% of genins
as sum of asiatic acid and madecassic acid by HPLC

Antiwrinkles, Stretchmarks improver

CENTEVITA® - CENTELLA ASIATICA

K

Centella asiatica (L.) Urban - Leaf

≥45.0% of the sum of asiaticoside, madecassoside,
asiatic and madecassic acids by HPLC

Antioxidant activity,
Collagen restructurant

CHAMOMILEK

Matricaria chamomilla L. (syn. Matricaria recutita L.)
Flowering head, ligula≥1.2% of total apigenin by HPLC

Spasmolytic, Soothing

ANTHOCRAN® - CRANBERRY

HK

Vaccinium macrocarpon Ait. - fruit≥27.0% ≤33.0% of proanthocyanidins by spectrophotometry (DMAC method)

Urinary tract health

DEVIL’S CLAW (100% procumbens )H

Harpagophytum procumbens DC. - Root

≥1.8% ≤2.2% of harpagoside by HPLC

Joint health

DEVIL’S CLAW

K

Harpagophytum procumbens DC. & zeyheri Decne - Root

≥1.8% ≤2.2% of harpagoside by HPLC

Joint health

IMMUNOSELECT®
ECHINACEA ANGUSTIFOLIA

K

Echinacea angustifolia DC. - Root

≥4.0% of echinacoside by HPLC

Immune system health,
Antioxidant activity

POLINACEA®
ECHINACEA ANGUSTIFOLIA

Echinacea angustifolia DC. - Root

≥2.0% of echinacoside by HPLC, ≥5.0% of polysaccharide IDN 5405,≤0.1% of isobutylamides

Immune system health

β-ESCIN (CRYSTALLINE)

Aesculus hippocastanum L. - Seed

≥97.0% ≤103% by potentiometry

Antioedema, Capillarotropic

β-ESCIN (AMORPHOUS)

Aesculus hippocastanum L. - Seed

≥95.0% by potentiometry

Antioedema, Capillarotropic

GINKGOSELECT®
GINKGO BILOBA

K

Ginkgo biloba L. - Leaf

≥24.0% of ginkgoflavonglucosides, ≥6.0% as a sum of ginkgolides A, B,
C, ≤5.0 ppm of total ginkgolic acids by HPLC

Blood circulation health

GINKGOSELECT® PLUS
ETHANOLIC EXTRACT

H

Ginkgo biloba L. - Leaf

≥22.0% ≤27.0% of ginkgoflavoglucosides, ≥4.0% ≤8.0% as sum of
ginkgolides A, B,C and bilobalide, ≤5.0 ppm of total ginkgolic acids by
HPLC

Cognition and circulation health,
Antioxidant activity

VIRTIVA® PLUS - GINKGO BILOBA
PHOSPHATIDYLSERINEHK

Ginkgo biloba L. - Leaf

≥5.0% of ginkgoflavonglucosides, ≥0.5% of ginkgoterpenes,≥12.0% of phosphatidylserine by HPLC

Cognitive health

PHARMACEUTICAL

Indena’s Active Pharmaceutical Ingredients are produced incompliance with cGMPs and in pharmaceutical inspected
plants, supported by CTD-DMFs.

HEALTH - FOOD

Indena’s ingredients for food supplements are produced
under Hazard Analysis and Crytical Control Points (HACCP)
in authorized areas.

12

HALAL
certified

E
C

ECOCERT
validated
CEP
grantedKOSHER
certified

Co
G

PACKAGING MATERIALS :: Foodgrade polyethylene bags, multilayerbags :: Kraft type cardboard drums,
metallic drums, polyethylene drums,
polypropylene pails (UN approved
drums are used for hazardous products)

COSMOS
validated

GRAS: the product can be used as
an ingredient in common food (US)13

STANDARDIZED, PURIFIED or OTHER
CHARACTERIZED DRY EXTRACTS
DRY EXTRACTS WITH REPRODUCIBLE CONTENTOF CHARACTERISTIC CONSTITUENTS(continue)
BRAND - ENGLISH NAMEBOTANICAL ORIGINASSAYBIOLOGICAL ACTIVITY

Ginkgo biloba L. - Leaf

≥22.0% ≤27.0% of flavonoids, ≥2.6% ≤3.2% of bilobalide,≥2.8% ≤3.4% of ginkgolides A,B,C, ≤5.0 ppm of ginkgolic acids by HPLC

Blood circulation health

GINSENG Re >1%

Panax ginseng C.A. Meyer - Root

≥10.0% of total ginsenosides;≥1.0% of ginsenoside Re by HPLC

Adaptogen, Tonic

GINSENG 2%

Panax ginseng C.A. Meyer - Root

≥2.0% of total ginsenosides by spectrophotometry

Adaptogen, Tonic

GINSENG 10%

Panax ginseng C.A. Meyer - Root

≥9.0% ≤11.0% of total ginsenosides by spectrophotometry

Adaptogen, Tonic

GINKGO BILOBA EUR. PH.

CGINSENG 10%

HK

Panax ginseng C.A. Meyer - Root

≥8.0% ≤12.0% of total ginsenosides by HPLC

Adaptogen, Tonic

GINSENG 20%

K

Panax ginseng C.A. Meyer - Root

≥18.0% ≤22.0% of total ginsenosides and malonylginsenosides by HPLC

Adaptogen, Tonic

GINSENG 27-30%

H

Panax ginseng C.A. Meyer - Root

≥27.0% ≤30.0% of saponins by spectrophotometry;≥20.0% of total ginsenosides by HPLC

Adaptogen, Tonic

GINSELECT® - GINSENG IDB

HPanax ginseng C.A. Meyer - Root

≥7.0% of ginsenosides and malonylginsenosides,≥0.9% ≤1.4% of Rg1, ≥1.7% ≤3.0% of Rb1 by HPLC

Adaptogen, Tonic

RED LEAF GRAPE

H

Vitis vinifera L. - Leaf

≥3.0% of total flavonoids (isoquercitrin, quercetin-3-O-b-D-glucuronide
and kaempferol-3-O-glucoside) by HPLC;≥0.3% of anthocyanins by spectrophotometry

Antioxidant activity, Capillarotropic

LEUCOSELECT®
GRAPE SEED EXTRACTHK

Vitis vinifera L. - Seed

≥95.0% ≤105.0% of proanthocyanidins by GPC;
≥13.0% ≤19.0% of catechin and epicatechin by HPLC

Antioxidant activity, Capillarotropic

ENOVITA®
GRAPE SEED EXTRACT

GHK

Vitis vinifera L. - Seed

≥95.0% of proanthocyanidins by spectrophotometry,≥5.0% ≤15.0% of catechin and epicatechin by HPLC

Antioxidant activity, Capillarotropic

GRAPE SEED MONOMERS

H

Vitis vinifera L. - Seed

≥20.0% ≤30.0% of monomers (catechin and epicatechin),≥20.0% of dimers by HPLC

Antioxidant activity, Capillarotropic

GREENSELECT® - GREEN TEA

K

Camellia sinensis (L.) Kuntze - Leaf

≥60.0% of catechins, ≥40.0% of (-)-epigallocatechin-3-O-gallate, ≤0.1%
of caffeine by HPLC

Antioxidant activity

PHARMACEUTICAL

Indena’s Active Pharmaceutical Ingredients are produced incompliance with cGMPs and in pharmaceutical inspected
plants, supported by CTD-DMFs.

HEALTH - FOOD

Indena’s ingredients for food supplements are produced
under Hazard Analysis and Crytical Control Points (HACCP)
in authorized areas.

14

HALAL
certified

E
C

ECOCERT
validated
CEP
grantedKOSHER
certified

Co
G

PACKAGING MATERIALS :: Foodgrade polyethylene bags, multilayerbags :: Kraft type cardboard drums,
metallic drums, polyethylene drums,
polypropylene pails (UN approved
drums are used for hazardous products)

COSMOS
validated

GRAS: the product can be used as
an ingredient in common food (US)15

STANDARDIZED, PURIFIED or OTHER
CHARACTERIZED DRY EXTRACTS
DRY EXTRACTS WITH REPRODUCIBLE CONTENTOF CHARACTERISTIC CONSTITUENTS(continue)
BRAND - ENGLISH NAMEBOTANICAL ORIGINASSAYBIOLOGICAL ACTIVITY

GREEN TEA

H

Camellia sinensis (L.) Kuntze - Leaf

≥30.0% of total polyphenols by spectrophotometry

Tonic, Body weight balance,
Antioxidant activity

GUARANAK

Paullinia cupana Kunth - Seed

≥11.0% ≤13.0% of total alkaloids by HPLC

Tonic, Mild diuretic, Lipolytic

HAWTHORN

K

Crataegus spp. - Leaf and flower≥1.8% of vitexin-2”-O-rhamnoside by spectrophotometry

Cardiovascular health, Antioxidant activity

HEDGE MUSTARD

H

Sisymbrium officinale (L.) Scop. - Aerial part

≥1.0% of glucosinolates by HPLC

Throat and upper respiratory tract health

HORSE CHESTNUT

K

Aesculus hippocastanum L. - Seed

≥18.0% ≤22.0% of saponins by spectrophotometry or 6.5-10-0% of totaltriterpene glycosides expressed as protoaescigenin (dried extract) acc.to
Ph. Eur #1829 by HPLC

Antioedema, Capillarotropic

HORSETAILK

Equisetum arvense L. - Sterile aerial part≥2.6% ≤3.2% of silica and ≥0.8% of total flavonoids expressed as
isoquercetin by spectrophotometry

Hair and nail health

IVY DRY HYDROALCOHOLIC EXT. 5%

K

Hedera helix L. - Leaf

≥5.0% of hederacoside C by HPLC

Capillarotropic,
Throat and upper respiratory tract health

IVY DRY HYDROALCOHOLIC EXT. 10%

K

Hedera helix L. - Leaf

≥10.0% of hederacoside C by HPLC

Capillarotropic,
Throat and upper respiratory tract health

LEMON BALM

K

Melissa officinalis L. - Leaf

≥10.0% of hydroxycinnamic derivates calculated as rosmarinic acid
≥2.0% of rosmarinic acid by HPLC

Healthy mood

LINDEN TREEK

Tilia cordata Mill. /Tilia platyphyllos Scop. /Tilia x vulgaris Heyne- Inflorescence≥0.5% of flavonoids by HPLC

Spasmolytic, Healthy mood, Antioedema

LYMPHASELECT® - MELILOTUS

K

Melilotus officinalis (L.) Pall.
(Homonym Melilotus officinalis (L.) Lam.) - Aerial part≥17.0% ≤20.0% of coumarin by HPLC

Lymphatic circulation health

PHARMACEUTICAL

Indena’s Active Pharmaceutical Ingredients are produced incompliance with cGMPs and in pharmaceutical inspected
plants, supported by CTD-DMFs.

HEALTH - FOOD

Indena’s ingredients for food supplements are produced
under Hazard Analysis and Crytical Control Points (HACCP)
in authorized areas.

16

HALAL
certified

E
C

ECOCERT
validated
CEP
grantedKOSHER
certified

Co
G

PACKAGING MATERIALS :: Foodgrade polyethylene bags, multilayerbags :: Kraft type cardboard drums,
metallic drums, polyethylene drums,
polypropylene pails (UN approved
drums are used for hazardous products)

COSMOS
validated

GRAS: the product can be used as
an ingredient in common food (US)17

STANDARDIZED, PURIFIED or OTHER
CHARACTERIZED DRY EXTRACTS
DRY EXTRACTS WITH REPRODUCIBLE CONTENTOF CHARACTERISTIC CONSTITUENTS(continue)
BRAND - ENGLISH NAMEBOTANICAL ORIGINASSAYBIOLOGICAL ACTIVITY

OLEASELECT® - OLIVEHK

Olea europaea L. - Fruit≥1.5% of hydroxytyrosol, ≥5.0% of verbascoside; ≥15% of hydroxytyrosol
abd its derivatives by HPLC

Antioxidant activity,
Cardiovascular health

OPEXTAN® - OLIVE

GHK

Olea europaea L. - Fruit≥10.0% of total polyphenols by spectrophotometry; ≥2.0% ≤3.5% of
verbascoside, ≥4.5% of hydroxytyrosol and its derivatives by HPLC

Antioxidant activity, Cardiovascular health,
UV protectant

PASSION FLOWER

K

Passiflora incarnata L. - Aerial part

≥1.5% of flavonoids as isovitexin acc.to Ph. Eur #1882 by LC

Healthy mood

PASSION FLOWER 4%

K

Passiflora incarnata L. - Aerial part3.0-5.0% of flavonoids as isovitexin acc.to Ph. Eur #1882 by LC

Healthy mood

RHODIOLA 3%

Rhodiola rosea L. - Root

≥3.0% ≤4.0% of total rosavins; ≥1.0% ≤2.0% of salidroside by HPLC

Adaptogen, Tonic

RHODIOLA 5%

Rhodiola rosea L. - Root

≥5.0% of total rosavins; ≥1.8% of salidroside by HPLC

Adaptogen, Tonic

RHUBARB 5%

K

Rheum palmatum L.,
Rheum officinale Baill. - Rhizome and root

≥5.0% ≤6.1% of hydroxyanthracenics derivates expressed as rhein
calculated on dried extract

Eupeptic, Laxative, Gut health

RHUBARB 10%

K

Rheum australe D. Don (syn. Rheum emodi
Wall. ex Meisn.) - Rhizome and root

≥9.0% ≤11.0% of total anthraquinones calculated as aloe-emodin byspectrophotometry

Eupeptic, Laxative, Gut health

RUSCOGENINS 60%

Ruscus aculeatus L. - Rhizome and root

≥60.0% ≤73.0% of ruscogenins + neoruscogenins by HPLC

Antihaemorrhoidal, Venotropic

RUSCOGENINS

Ruscus aculeatus L. - Rhizome and root

≥95.0% ≤103.0% of ruscogenins, ≥65.0% ≤80.0% neoruscogenin,≥20.0% ≤35.0% ruscogenin by HPLC

Antihaemorrhoidal, Venotropic

SENNOSIDES ACID 45%

Cassia angustifolia Vahl. - Leaf

≥42.0% ≤56.0% of hydroxyanthracene glycosides, calculated as
sennoside B by spectrophotometry; ≥38.0% ≤44.0% of sennosides,
calculated as sum of Sennoside A and Sennoside B by HPLC

Laxative

SENNOSIDES 45%

Cassia angustifolia Vahl. - Leaf

≥42.5% ≤47.5% of hydroxyanthracene glycosides, calculated as
sennoside B by spectrophotometry

Laxative

SILYMARIN

K

Silybum marianum (L.) Gaertn.
Fruit without pappum

Extraction solvent: ethyl acetate≥50.0% ≤60.0% of silymarin calculated as silybin by HPLC according
to Ph. Eur. (corresponding to NTL 80% of flavonoids as silibinin
monohydrate by spectrophotometry)

Liver diseases,
Healthy liver, Antioxidant activity

ST. JOHN’S WORTC

Hypericum perforatum L. - Flowering top≥0.10% ≤0.30% of total hypericin, ≥6.0% of flavonoids,≤6.0% of hyperforin by HPLC

Antidepressant

PHARMACEUTICAL

Indena’s Active Pharmaceutical Ingredients are produced incompliance with cGMPs and in pharmaceutical inspected
plants, supported by CTD-DMFs.

HEALTH - FOOD

Indena’s ingredients for food supplements are produced
under Hazard Analysis and Crytical Control Points (HACCP)
in authorized areas.

18

HALAL
certified

E
C

ECOCERT
validated
CEP
grantedKOSHER
certified

Co
G

PACKAGING MATERIALS :: Foodgrade polyethylene bags, multilayerbags :: Kraft type cardboard drums,
metallic drums, polyethylene drums,
polypropylene pails (UN approved
drums are used for hazardous products)

COSMOS
validated

GRAS: the product can be used as
an ingredient in common food (US)19

STANDARDIZED, PURIFIED or OTHER
CHARACTERIZED DRY EXTRACTS
DRY EXTRACTS WITH REPRODUCIBLE CONTENTOF CHARACTERISTIC CONSTITUENTS(continue)
BRAND - ENGLISH NAMEBOTANICAL ORIGINASSAYBIOLOGICAL ACTIVITY

VALERIAN EXTRACT

K

Valeriana officinalis L. - Rhizome and root

≥0.25% of sesquiterpenic acids, expressed as valerenic acid, calculatedon the anhydrous substance by HPLC

Sleep disorders, Healthy mood

VALEROSELECT® - VALERIAN EXTRACTKC

Valeriana officinalis L. - Rhizome and root

≥0.25% of sesquiterpenic acids, expressed as valerenic acid, calculatedon the anhydrous substance; ≥0.8 - 1.0% of valerenic acids by HPLC

Sleep disorders, Healthy mood

Zingiber officinale Roscoe - Rhizome
Acmella oleracea (I) R.K. Jensen - Aerial part

≥9.6% ≤11.8% Zingiber officinale CO2 standardized extract≥1.9% ≤2.4% Acmella oleracea standardized extract

Ache relief

MITIDOL®
ZINGIBER AND ACMELLAPHARMACEUTICAL

Indena’s Active Pharmaceutical Ingredients are produced incompliance with cGMPs and in pharmaceutical inspected
plants, supported by CTD-DMFs.

HEALTH - FOOD

Indena’s ingredients for food supplements are produced
under Hazard Analysis and Crytical Control Points (HACCP)
in authorized areas.

20

HALAL
certified

E
C

ECOCERT
validated
CEP
grantedKOSHER
certified

Co
G

PACKAGING MATERIALS :: Foodgrade polyethylene bags, multilayerbags :: Kraft type cardboard drums,
metallic drums, polyethylene drums,
polypropylene pails (UN approved
drums are used for hazardous products)

COSMOS
validated

GRAS: the product can be used as
an ingredient in common food (US)21

CHARACTERIZED, STANDARDIZEDOILY and SOFT EXTRACTSOILY / SOFT EXTRACTS WITH REPRODUCIBLE CONTENTOF CHARACTERISTIC CONSTITUENTS
BRAND - ENGLISH NAMEBOTANICAL ORIGINASSAYBIOLOGICAL ACTIVITYCURBILENE®
CUCURBITA PEPO CO2 EXTRACT

Cucurbita pepo L - Seed≥85.0% of fatty acids by GC

Prostate health

Vaccinium myrtillus L. - Seeds≥80.0% of total fatty acids by GC; ≥50% total polyunsaturated fatty acids by GLC

Cholesterol health

PRUNUSPYGEUM AFRICANUM

Prunus africana (Hook. F.) Kalkm.
(syn. Pygeum africanum Hook. f.) - Bark

≥13% of total sterols by spectrophotometry

Prostate health and bladder function

CHINESE RHUBARB SOFT
AQUEOUS EXTRACT

Rheum palmatum L. - Rhizome and Root

≥1.0% of anthraquinones as aloe-emodin by spectrophotometry

Laxative, Gut health

Serenoa repens (Bartr.) Small - Fruit≥85.0% ≤95.0% of fatty acids, ≥0.15% ≤0.3% of fatty alcohols,≥0.2% ≤0.4% of total sterols, ≥0.1% ≤0.3% of β-sitosterol by GC

Prostate health and bladder function

Serenoa repens (Bartr.) Small - Fruit≥80.0% of total fatty acids, ≥23.0% of lauric acid,≥0.20% of total sterols as β-sitosterol, ≥0.10% of β-sitosterol by GC

Antiandrogen, Anti-BPH

Serenoa repens (Bartr.) Small - Fruit≥80.0% of total fatty acids, ≥23.0% of lauric acid,≥0.20% of total sterols as β-sitosterol, ≥0.10% of β-sitosterol by GC

Antiandrogen, Anti-BPH,
Prostate health and bladder function

OMEGABLUE® - BILBERRY SEEDSABALSELECT®
SAW PALMETTO CO2 EXTRACTECoK

SAW PALMETTO CO2 EXTRACTSAW PALMETTO
ALCOHOLIC EXTRACTKC

PHARMACEUTICAL

Indena’s Active Pharmaceutical Ingredients are produced incompliance with cGMPs and in pharmaceutical inspected
plants, supported by CTD-DMFs.

HEALTH - FOOD

Indena’s ingredients for food supplements are produced
under Hazard Analysis and Crytical Control Points (HACCP)
in authorized areas.

22

HALAL
certified

E
C

ECOCERT
validated
CEP
grantedKOSHER
certified

Co
G

PACKAGING MATERIALS :: Foodgrade polyethylene bags, multilayerbags :: Kraft type cardboard drums,
metallic drums, polyethylene drums,
polypropylene pails (UN approved
drums are used for hazardous products)

COSMOS
validated

GRAS: the product can be used as
an ingredient in common food (US)23

PHYTOSOME®

BRAND - ENGLISH NAMEBOTANICAL ORIGINASSAYBIOLOGICAL ACTIVITY

Vaccinium macrocarpon Ait. - fruit≥6.0% ≤9.0% of proanthocyanidins by spectrophotometry (DMAC method)

Urinary tract health

BERBEVIS®
BERBERIN PHYTOSOME®

Berberis aristata L. - Root

≥28.0% ≤34.0% of berberine by HPLC

Healthy metabolism

CASPEROME®
BOSWELLIA PHYTOSOME®

Boswellia serrata Roxb. ex Colebr. - Resin≥25.0% of triteroenic acids (boswellic acids and lupeolic acids) and
derivatives by HPLC

Healthy inflammatory response,
Joint health, Gut health

CUBO™
CURCUMIN PHYTOSOME® +BOSWELLIA PHYTOSOME®

Curcuma longa L. - Rhizome
Boswellia serrata Roxb. ex Colebr. - Resin≥11.9% ≤14.5% of totalcurcuminoids,≥8.25% of total triterpenic acids by HPLC

Gut health

ANTHOCRAN® PHYTOSOME®
CRANBERRY PHYTOSOME®

HGINKGOSELECT® PLUS PHYTOSOME®
GINKGO BILOBA PHYTOSOME®

HK

Ginkgo biloba L. - Leaf

≥7.0% of ginkgoflavonglucosides, ≥2.0% of ginkgoterpenes, ≥0.8% of
ginkgolides, ≤5 ppm of total ginkgolic acids by HPLC

Cognition and circulation health,
Antioxidant activity, Vasokinetic

GREENSELECT® PHYTOSOME®
GREEN TEA PHYTOSOME®

HK

Camellia sinensis (L.) O. Kuntze - Leaf

≥19.0% ≤25.0% of polyphenols expressed as (-)-epigallocatechin-3-Ogallate, ≥13.0% of (-)-epigallocatechin-3-O-gallate,≤0.1% of caffeine by HPLC

Body weight balance, Antioxidant activity

LEUCOSELECT® PHYTOSOME®
GRAPE SEED PHYTOSOME®

HK

Vitis vinifera L. - Seed

≥25.0% ≤30.0% of proanthocyanidins by GPC

Cardiovascular health,
UV protectant, Antioxidant activity

SILYMARIN PHYTOSOME®

HK

Silybum marianum (L.) Gaertn. - Fruit≥15.0% ≤20.0% of silymarin calculated as silybin by HPLC

Healthy liver, Antioxidant activity,
UV protectant

SILIPHOS®
SILYBIN PHYTOSOME®

HK

Silybum marianum (L.) Gaertn. - Fruit≥29.7% ≤36.3% of silybin by HPLC

Healthy liver,
Retinoic acid-like activity

MERIVA®
CURCUMINOIDS PHYTOSOME®

HK

Curcuma longa L. - Rhizome≥18.0% ≤22.0% of curcuminoids by HPLC

Joint health, Healthy inflammatory
response

PHARMACEUTICAL

Indena’s Active Pharmaceutical Ingredients are produced incompliance with cGMPs and in pharmaceutical inspected
plants, supported by CTD-DMFs.

HEALTH - FOOD

Indena’s ingredients for food supplements are produced
under Hazard Analysis and Crytical Control Points (HACCP)
in authorized areas.

24

HALAL
certified

E
C

ECOCERT
validated
CEP
grantedKOSHER
certified

Co
G

PACKAGING MATERIALS :: Foodgrade polyethylene bags, multilayerbags :: Kraft type cardboard drums,
metallic drums, polyethylene drums,
polypropylene pails (UN approved
drums are used for hazardous products)

COSMOS
validated

GRAS: the product can be used as
an ingredient in common food (US)25

PHYTOSOME®
(continue)

BRAND - ENGLISH NAMEBOTANICAL ORIGINUBIQSOME®
COENZYME Q10 PHYTOSOME®

-

ASSAY

BIOLOGICAL ACTIVITY≥18.0% ≤22.0% of coenzyme Q10 by HPLC

Cells bioenergetics support, sports
nutrition, healthy ageing, heart &cardiovascular health, brain health

VAZGUARD®
BERGAMOT PHYTOSOME®

Citrus bergamia Risso & Poit. - Fruit juice≥14.0% ≤18.0% of total flavanols by HPLC

Healthy blood levels, Visceral fat optimizer

QUERCEFIT®
QUERCETIN PHYTOSOME® SF/MD

Sophora japonica L. - Flowering head

≥34.0% ≤42.0% of quercetin by HPLC

Sports nutrition, Antioxidant activity

RELISSA™
MELISSA PHYTOSOME®

Melissa officinalis L. - Leaf

≥17.0% ≤23.0% of hydroxycinnamic acids by HPLC

Quality sleep, mood

PHARMACEUTICAL

Indena’s Active Pharmaceutical Ingredients are produced incompliance with cGMPs and in pharmaceutical inspected
plants, supported by CTD-DMFs.

HEALTH - FOOD

Indena’s ingredients for food supplements are produced
under Hazard Analysis and Crytical Control Points (HACCP)
in authorized areas.

26

HALAL
certified

E
C

ECOCERT
validated
CEP
grantedKOSHER
certified

Co
G

PACKAGING MATERIALS :: Foodgrade polyethylene bags, multilayerbags :: Kraft type cardboard drums,
metallic drums, polyethylene drums,
polypropylene pails (UN approved
drums are used for hazardous products)

COSMOS
validated

GRAS: the product can be used as
an ingredient in common food (US)27

INDENA S.A.S.
7, Rue Lamennais
75008 Paris - France
tel. +33 1 45229128
INDENA USA Inc.
600 University Street,
Suite 3011
Seattle, WA 98101 - USA
tel. +1 206 340 6140

indena.com

03/2011*
DPR0002 -DPR0002
03/2011*-03/2023
trademarks of Indena S.p.A. © 2023, Indena S.p.A.

INDENA JAPAN Co., Ltd.
KDDI Bld. 21F. 1-8-1 Otemachi
Chyoda-Ku Tokyo 100-0004 - Japantel. +81 3 3243 9924,

INDENA Brasil Ltda
Rua Bandeira Paulista, 600
CEP 04532-001
São Paulo - Brazil
tel. +55 1 127 690 624® TM

INDENA BIOTECHNOLOGY (Shanghai) Co., Ltd.
Unit 1006, Plaza 336
336 Middle XiZang Road
200001 Shanghai
Chinatel. +86 21 2281 5900

07/2023

HEADQUARTERS - INDENA S.p.A.
Viale Ortles, 1220139 Milan - Italytel. +39 02 574961