(57)【要約】【課題】ストマチン分子の知覚センサーやイオンチャネル等重要機能分子への制御機能を解明するため、ストマチンの結晶を作成し、これを用いてストマチンの三次元構造を明らかにする。【解決手段】ストマチンの可溶性中核ドメインからなる欠失変異体を該ストマチンのホモ三量体構造を保持しながら取得し、該変異体の結晶を作成してＸ線回折を行い、原子座標からストマチンの三次元構造を求める。【選択図】なし【特許請求の範囲】
【請求項１】
パイロコッカス・ホリコシ由来のストマチンの欠失変異体であって、該ストマチンの５６番目から、２１３乃至２４０番目までのアミノ酸配列からなるか、あるいはパイロコッカス・ホリコシ以外の生物由来のストマチンの欠失変異体であって、該アミノ酸配列とのアライメントをとるとき対応部分以外の領域を含まず、かつ、該アミノ酸配列と３５％以上の相同性を有するアミノ酸配列からなることを特徴とする、ストマチンの欠失変異体。
【請求項２】
請求項１に記載の欠失変異体の結晶。
【請求項３】
結晶の空間群がＣ2であり格子定数がa＝142.6Å、ｂ＝137.2Å、ｃ＝58.5Å、β＝107.6°である請求項２記載の欠失変異体の結晶。
【請求項４】
結晶の大きさが0.30×0.20×0.05ｍｍまでのものであることを特徴とする請求項２または３に記載のStoCDの結晶。
【請求項５】
請求項１に記載の欠失置換体を精製した後、トリス塩酸緩衝液（pH7.5）に溶解し、沈殿剤として2-メチル-2,4-ペンタンジオール(MPD)、硫酸アンモニウム、1,5ジアミノペンタン-塩酸の混液を用い、ハンギングドロップ法により結晶化することを特徴とする請求項２〜４のいずれかに記載の結晶の製造方法。
【請求項６】
2-メチル-2,4-ペンタンジオール(MPD)の濃度が14％〜20％である沈殿剤溶液を用いる請求項５記載の製造方法。
【請求項７】
欠失変異体濃度が3.7〜5.0 mg/mlであることを特徴とする請求項５または６に記載の製造方法。
【発明の詳細な説明】
【技術分野】
【０００１】
本発明はストマチンの可溶性中核ドメイン(StoCD)からなる欠失変異体、その結晶及び該結晶の製造方法に関する。
【背景技術】
【０００２】
ストマチンはヒト赤血球膜に豊富に存在する膜タンパク質として発見され、その遺伝的欠損はストマトサイトーシスと呼ばれる遺伝性溶血性貧血を引き起こすことが知られている。このことからストマチンは一価陽イオンチャンネルタンパク質の負の制御因子と考えられている。一方、接触と機械的な痛みを最初に感じるのは、最大の感覚表面である皮膚である。このような刺激を感じ取る感覚ニューロンにはサブタイプがあって、特定の機械的刺激を特異的に感知する。線虫(Caenorhabditis elegans)の接触非感受性についてのスクリーニングで見つかった一つの遺伝子がmec-2で、ストマチンの中核ドメインを含む膜タンパク質をコードしている(非特許文献１)。
一方、機械感覚に必要な分子は哺乳類では見つかっていなかった。しかし、最近マウスのストマチンホモログ(Stomatin-like protein 3, SLP3)に変異のある個体は皮膚の機械受容器の約35%が機械刺激に反応しないことが報告された(非特許文献２)。
SLP3は哺乳類が持つmec-2ホモログで、感覚ニューロンで発現されている。また、多くの感覚ニューロンに見られる機械受容イオンチャンネルはSLP3がないと機能しない。SLP3変異マウスでは神経の損傷が原因で起こる接触時の痛みのような、触覚で起きる行動も損なわれている。この様にストマチン中核ドメインを含むSLP3は皮膚のある種の機械受容器の機能に不可欠であり、哺乳類の機械刺激変換装置の必須サブユニットと考えられる。さらに、哺乳動物の神経細胞の非電圧開閉型Na+チャンネルである、酸-センシングイオンチャンネルタンパク質(Acid-sensing ion channels, ASICs)の開閉が、ストマチンにより制御されていることも報告されている（非特許文献３）。よって、本発明は生体膜の動態に深く関与すると考えられるストマチン分子の知覚センサーやイオンチャネル等機能分子への制御機能を精査する上で、非常に重要な構造知見を与える。
【０００３】
ストマチンがヒト、マウスおよび線虫の接触感覚受容器や痛覚受容器を構成することが発見された（非特許文献２）C. Wetzel et al. (2006) Nature, 445, 206-209、(2007)。しかし、その制御機構の詳細は未知である。さらに、ストマチンは全生物に普遍的に存在し、その一次配列は高い保存性を有する。よって、ストマチン分子の知覚センサーやイオンチャネル等機能分子への制御能の精査を可能にするため、もしくはストマチンの生体膜機能制御能を阻害或いは修飾する薬剤を開発するために、StoCDの分子機能構造解明が渇望されていた。
【０００４】
【非特許文献１】M. B. Goodman, et al. (2002) Nature, 415, 1039-1042
【非特許文献２】C. Wetzel, et al. (2007) Nature, 445, 206-209
【非特許文献３】M. P. Price et al. (2004) J. Biol. Chem., 279, 53886-53891
【発明の開示】
【発明が解決しようとする課題】
【０００５】
膜タンパクであるストマチン(Stomatin)のアミノ酸一次配列が全生物種（古細菌、バクテリア、真核生物）で高度に保存されている（図1）ことから、PhStoCD分子構造は、生体膜機能制御能を有するヒトを含む全ての生物由来のストマチン中核ドメイン構造をホモロジーモデリング法で予測ための鋳型として活用できる。よって、本発明の目的は、ストマチンの立体構造を保持させつつ、ストマチン中核ドメインを高発現させて、該ドメインの結晶を取得し、該結晶を用いてストマチンの立体構造を明らかにするとともに、ストマチン分子の知覚センサーやイオンチャネル等重要機能分子への制御機能を立体構造的に解明することにあり、さらには、その生体膜制御能を阻害あるいは修飾する薬剤を開発し、また、立体構造の類似する機能未知の蛋白質を見いだしその機能を明らかにすることにある。
【課題を解決するための手段】
【０００６】
本発明者らは、超好熱菌パイロコッカス・ホリコシ由来のストマチン遺伝子（PH1511）を用い、266アミノ酸残基からなる全長分子のアミノ末端（N-末）とカルボキシ末端（C-末）を異なる程度に欠損させた変異遺伝子を作成し、遺伝子組み換え法で変異遺伝子を発現させ、欠失分子の高発現に成功した。また、高発現された欠失分子の精製を行い、それら変異体を用いてタンパク質結晶化を試みた。その結果、56残基から234残基領域をふくむストマチン可溶性中核ドメイン(PhStoCD)が生産性と安定性に優れ、タンパク質結晶に最も適していることを見いだした。さらに、該分子の三次元構造を解明し得る高品位の結晶を得るべく鋭意検討を重ねた結果、高分解能でＸ線解析を行いうる結晶の取得し、これを用いてその３次元構造を明らかにすることに成功し、本発明を完成するに至った。
すなわち、本発明は以下のとおりである。
【０００７】
（１）パイロコッカス・ホリコシ由来のストマチンの欠失変異体であって、該ストマチンの５６番目から、２１３乃至２４０番目までのアミノ酸配列からなるか、あるいはパイロコッカス・ホリコシ以外の生物由来のストマチンの欠失変異体であって、該アミノ酸配列とのアライメントをとるとき対応部分以外の領域を含まず、かつ、該アミノ酸配列と３５％以上の相同性を有するアミノ酸配列からなることを特徴とする、ストマチンの欠失変異体。
（２）上記（１）に記載の欠失変異体の結晶。
（３）結晶の空間群がＣ2であり格子定数がa＝142.6Å、ｂ＝137.2Å、ｃ＝58.5Å、β＝107.6°である上記（２）記載の欠失変異体の結晶。
（４）結晶の大きさが0.30×0.20×0.05ｍｍまでのものであることを特徴とする上記（２）または（３）に記載のStoCDの結晶。
（５）請求項１に記載の欠失置換体を精製した後、トリス塩酸緩衝液（pH7.5）に溶解し、沈殿剤として2-メチル-2,4-ペンタンジオール(MPD)、硫酸アンモニウム、1,5ジアミノペンタン-塩酸の混液を用い、ハンギングドロップ法により結晶化することを特徴とする上記（２）〜（４）のいずれかに記載の結晶の製造方法。
（６）2-メチル-2,4-ペンタンジオール(MPD)の濃度が14％〜20％である沈殿剤溶液を用いる上記（５）に記載の製造方法。
（７）欠失変異体濃度が3.7〜5.0 mg/mlであることを特徴とする上記（５）または（６）に記載の製造方法。
【発明の効果】
【０００８】
本発明によれば、全ての生物由来のストマチンに関する結晶化に最適な欠失変異体が容易に創製でき、そのStoCDの結晶に基づいて得られる三次元構造を用いれば、その膜脂質との相互作用部位あるいはタンパク質相互作用部位のアミノ酸残基とその立体配置が明らかとなり、相互作用阻害剤等の医薬品探索のための候補を絞り込むことができる。また、このような三次元構造を用いることにより、該タンパク質の複合体形成に関与するアミノ酸残基の配置が明らかとなり、それによって機能変換型のStoCDを得るために変異させるべき残基を絞り込むことが可能となる。
【０００９】
一方、本発明により明らかになったPyrococcus horikoshii 由来のストマチン可溶性中核ドメイン(PhStoCD)の分子構造は同一サブユニットが3分子集合した三量体であり、PhStoCD単一サブユニット構造を用いたProtein Data Bank (PDB)への類似構造探索により、核磁気共鳴(NMR)法によって単量体構造が解明されたフロチリン-2 (Flotillin-2)のバンド-7ドメイン(PDB code, 1win)との高い構造類似性(Z score = 4.2)が見出されている。なお、最近、フロチリン（Reggie-2とも呼ばれる）はクラスリン非依存性エンドサイトシス（細胞食作用）経路を決定する膜タンパク質であると報告されているものである(O. O. Glebov et al. (2006) Nat. Cell Biol., 8, 46-54)。このように異なるタンパク質間の構造類似性の把握は、各蛋白質の機能の原因を把握するのに重要であり、新たな機能蛋白質の開発にもつながる。
したがって、本発明は産業上きわめて重要である。
【発明を実施するための最良の形態】
【００１０】
以下、本発明を詳細に説明する。
ストマチンは生体膜のラフト（生体膜上に浮かぶ筏の意）に局在することがよく知られている。ストマチンの立体構造の解明は、ストマチン分子の知覚センサーやイオンチャネル等重要機能分子への制御機能を精査する上で、あるいはストマチンの生体膜形態制御能を阻害或いは修飾する薬剤を開発する上できわめて重要である。
本発明においては、ストマチンの立体構造を解明するために、ストマチン可溶性中核ドメイン（Stomatin Core Domain; 以下StoCDと略記する場合がある。）からなる欠失変異体を調製し、これを用いて該変異体の結晶を得る。該結晶を得るための素材としては、例えば、パイロコッカス・ホリコシ由来の耐熱性ストマチンPH1511p（PH1511遺伝子にコードされるタンパク質の意）が好ましく用いられる（Kawarabayasi, Y. et al. (1998) DNA Res. 5, 55-76）。
【００１１】
パイロコッカス由来の耐熱性ストマチンPH1511pは、上記論文に記載されているように、266アミノ酸残基より構成され、その分子量は29,999Ｄａであり、等電点はpI=7.86と予測される。しかし、一般的に膜タンパク質は生体膜に組み込まれて安定化される膜貫通領域を含み（図2A）、疎水性が高いタンパク質のため大腸菌を用いた遺伝子組み換え法での発現は極めて困難である。実際に、本発明者は全長のストマチンPH1511pの発現を試みたが、発現産物中には内在性プロテアーゼで分解されたと予測された小分子生産物のみが検出された。
【００１２】
本発明は、耐熱性ストマチンPH1511pのN-末領域とC-末領域を異なる程度に欠損させた変異体（図2B）を作成し、これにより、パイロコッカス・ホリコシ由来の可溶性中核ドメイン（以下、PhStoCDと略記する場合がある。）の安定的な高生産及びその結晶化に成功したことに基づく。
パイロコッカス・ホリコシ由来のストマチンの上記欠失変異体は、結晶化とストマチンの立体構造保持の点から、ストマチンのα/βドメイン中のβ１〜β６、α１〜α５の領域、すなわち、パイロコッカス由来の耐熱性ストマチンPH1511pのアミノ酸配列のうち、５６番目から２１３番目の領域を必ず含むが、５５番目までの領域およびα６の領域中２４０番目以降の領域は結晶化に有害であり、５５番目までの領域及び２４１番目以降の領域は欠損させる必要がある。このような欠失変異体は、可溶性中核ドメインからなり、ストマチンのホモ３量体の構造を保持して発現され、高品質の結晶を与える。
一方、図１に示されるように、ストマチン(Stomatin)のアミノ酸一次配列が全生物種（古細菌、バクテリア、真核生物）で高度に保存されており、他の生物由来の蛋白質であっても、上記パイロコッカス・ホリコシ由来の可溶性中核ドメインと相同率において少なくとも４０％以上の領域を有するのであれば、パイロコッカス・ホリコシ由来のストマチンについての上記欠損操作と同様な操作を行うことにより、可溶性中核ドメインからなる結晶化可能な蛋白質が得られる。
【００１３】
図１中、ストマチンのオルソログの名称は以下のように略され、そのNCBI accession numberは以下のとおり、これらのアミノ酸配列は配列表に示される。
PH1511 (P. horikoshii)；NCBI accession number NP_143371、配列番号１
PAB1933 (P. abyssi)；NP_126340、配列番号２
PA0452 (Pseudomonas aeruginosa)；NP_249143、配列番号３
SMB20989 (Sinorhizobium meliloti)；NP_437654、配列番号４
MEC-2 (C. elegans)；NP_741797、配列番号５
stomatin (human)；NP_004090、配列番号６
【００１４】
本発明のストマチンの欠失変異体、すなわち可溶性中核ドメインからなる蛋白質は、ストマチンをコードする遺伝子を用い通常の遺伝子操作により取得することができる。
例えば、可溶性中核ドメインをコードする遺伝子の配列から、プライマーを設計し、ストマチン遺伝子部分を含むＤＮＡをテンプレートとして、ＰＣＲ増幅し、可溶性中核ドメインをコードする遺伝子を得て、遺伝子組換えにより得られた形質転換体を培養することにより、目的とする可溶性中核ドメインからなる蛋白質を得ることができる。
本発明においては、この後、精製、及び結晶化を行うが、精製は菌体の超音波破砕、遠心分離上清液の加熱処理、加熱上清の Ni-カラムクロマトグラフィー、陰イオン交換クロマトグラフィー、ゲルろ過カラムクロマトグラフィーの手順で行った。
【００１５】
一方、本願発明は、上記可溶性中核ドメインからなる欠失変異体を得て、ストマチンのホモ３量体の構造を保持させつつ、その結晶化に初めて成功し、その３次元構造を明らかにしたものである。以下これらの点について詳述する。
一般にタンパク質の結晶化は容易ではなく、多くのタンパク質の場合は、数多くの条件検討を重ねて初めてＸ線結晶構造解析に供することのできる結晶が得られる。また、いかなる条件でも結晶化しないタンパク質も決して少なくなく、タンパク質の結晶が得られなければＸ線結晶構造解析を行うことができず、従って、そのタンパク質の三次元構造を解明することはできない。
【００１６】
現在、タンパク質の三次元構造を決めるための方法として、ＮＭＲ（核磁気共鳴法）を利用することも可能である。ＮＭＲでは試料を結晶化する必要はなく、タンパク質溶液の状態で測定を行うことができる。しかし、ＮＭＲで構造を決めるのが可能なタンパク質は事実上分子量が１万以下に限定される。従って、分子量の大きなストマチン可溶性中核ドメインについては、Ｘ線結晶構造解析に頼らざるを得ないのが現状である。
また、Ｘ線結晶解析の際、タンパク質の結晶がいかなるものであっても解析可能であるわけではない。そのＸ線解析装置の能力によって違いはあるが、測定に供しうるタンパク質の結晶の条件としては、単結晶であって、その大きさが大きいものが好ましく、0.1ｍｍ角以上であることが求められる。いずれにしても、Ｘ線を当てた際に解析可能な分解能の回折強度データが得られることが必要である。特に、タンパク質のアミノ酸残基の向きまで含めた構造解析を行うのであれば、最低でも３Å程度の分解能が必要とされる。
【００１７】
本発明のストマチン欠失変異体、すなわち可溶性中核ドメインを結晶化するには、まず前記した結晶化の素材となるストマチン欠失変異体は、薄い緩衝液中に濃縮された状態で用意するのが好ましく、その際の緩衝液のpHは該酵素の安定pHの範囲内であることが望ましい。従って、必要に応じて、例えば、10〜100 mMのトリス塩酸緩衝液（pH7.5）にストマチン欠失変異体の濃度を8〜10 mg/ml程度まで濃縮する。次いで、ストマチン欠失変異体の濃縮液に種々の沈殿剤を加えることにより結晶化のための好適な沈殿剤を選定する。
【００１８】
本発明のストマチン欠失変異体の結晶化に使用する沈殿剤としては様々なものを用いることができ、例えば、硫酸アンモニウムなどの無機塩類、ポリエチレングリコール類、エタノールなどの有機溶媒類などが挙げられる。
沈殿剤は、2-メチル-2,4-ペンタンジオール(MPD)、硫酸アンモニウム、HEPES-NaOH (pH 7.5)、1,5ジアミノペンタン-塩酸の混液を用いるのが好適である。後記実施例に示すように、各種パイロコッカス・ホリコシ由来のストマチン欠失変異体のうち、ストマチンの５６〜２３４番目のアミノ散配列からなる1511-N3 (56-234)（PhStoCDとも略記される）素材とするときに結晶が得られることを見いだしている。
また、結晶化の温度は常温であればいかなる温度でもよいが、好ましくは約20℃で１週間以上静置すればよい。
【００１９】
上記条件における結晶化の実施態様としては、ハンギングドロップ法、透析法、シッティングドロップ法などの公知のいかなる方法でもよいが、好ましくは蒸気拡散法の一種であるハンギングドロップ法が好適に用いられる。
【００２０】
このハンギングドロップ法は、密閉系においてタンパク質を含む低濃度の沈殿剤溶液から高濃度の沈殿剤溶液に水が拡散してゆく原理を利用したものであり、最も一般的に用いられる結晶化方法である。
【００２１】
上記のようにして得られる結晶の外観、および結晶の最小単位である単位格子の種類・サイズ、格子内の分子の数・対称性などはその結晶に固有のものであり、同一のタンパク質でかつ沈殿剤の種類が同じであっても異なる結晶が得られることがある。ただし、同一のタンパク質であれば、結晶の外観が異なっていても分子の三次元構造は同一であると考えられる。
このような方法により、Ｘ線結晶構造解析に供してその三次元構造を側鎖レベルまで解明しうる品位を有する本発明のPhStoCDの結晶を得ることができる。
【００２２】
このようにして得られた結晶にＸ線を当てて回折強度データを得るには、通常の実験室レベルのＸ線回折装置としては、ＳＭＡＲＴ６０００(ブルカーＡＸＳ社)などが用いられるが、好ましくは放射光由来の強いＸ線を利用できる放射光施設、例えば、つくばの高エネルギー加速器研究機構の放射光施設にてＸ線回折強度データの収集を行うことが望ましい。
【００２３】
このようにして得られたＸ線回折強度データのパターンより結晶学的パラメーターを決定することができ、例えば、パイロコッカス・ホリコシ由来の可溶性中核ドメイン（PhStoCD）の結晶の場合は、単斜晶系に属しており、空間群がＣ２、格子定数がa＝142.6Å、ｂ＝137.2Å、ｃ＝58.5Å、β＝107.6°である。そして、計算により導き出される該結晶の溶媒含有率は71%であり、非対称単位内にPhStoCD三量体を１分子含むものと推定された。また、前記データの分解能は3.1Åであり、側鎖の向きも含めた三次元構造の決定が可能なレベルにあった。
【００２４】
次いで、上記のようにして得られたＸ線回折強度データに基づいてその結晶を構成する分子の電子密度図を導き出すためには、分子置換法、重原子同型置換法、セレノメチオニン誘導体を用いるmultiwavelength anomalous dispersion法（MAD法）による位相の決定が必要となるが、該分子の様にセレノメチオニン誘導体結晶が得られる場合は、MAD法を用いることができる。
【００２５】
次に、MAD法により良好な初期構造モデルが得られれば、その電子密度を描くことができ、それに基づいて、モデルの修正を、三次元グラフィックス上にて行うことができる。その際に、種々のプログラムを用いることが可能であるが、好ましくは、プログラム COOTを用いて、アミノ酸残基の違いの修正、電子密度からのずれの修正を行う。
【００２６】
さらに、構築された分子のモデルは種々のプログラムを用いて精密化する必要があるが、例えばREFMAC5などのプログラムによる精密化と、プログラムCOOTを用いた三次元グラフィックスによる修正作業を駆使して、より正解に近い構造へと近づけていくことができる。精密化の指標となるＲ因子の値が20％以下になることが目標とされている。例えば、後記実施例に示すように、当該PhStoCDの場合は、Ｒ因子が19.8％まで下がった時点で精密化を終えた。その結果得られたPhStoCD結晶の原子座標を表1に示す。
【００２７】
また、このような過程を経て得られたPhStoCDの三次元構造は図4と5に示される。
PhStoCDは新規なホモ3量体構造を有し、三つのα/βドメインが集合し一辺が約50Åからなる三角形構造体を形成し、三角形の各頂点から約60Åのα-ヘリカル構造体（α5）が三本伸びている（図4Aは三つのα/βドメインが形成する三角形構造体を上面から俯瞰したステレオ図、図4Bは側面からのステレオ図）ことが分かる。
PhStoCDのα/βドメインはマウス由来のフロチリン-2 (Flotillin-2)のバンド-7ドメイン(PDB code, 1win)との高い構造類似性(Z score = 4.2)が見出される。立体構造から明らかになった二次構造配列は図1に示される。
【００２８】
α/βドメインはN末端側からβ-sheet 1 (β1)、β2、β3、β4、α-helix 1 (α1)、α2、α3、α4、β5、β6の順に二次構造がfoldし、相対的に堅いα/βドメイン構造を形成している。一方、三つのα/βドメインが形成する三角形構造体から伸びる長いα-ヘリカル構造体（α5）（残基170-213に相当）は柔軟で、周りの環境に適応し、三角形構造体からの角度が可変と考えられる。また、図4と5から、一つのサブユニットのβ1（残基56-60）が隣のサブユニットのβ6（残基165-169）と相互作用し、主要サブユニット界面を形成していることが明らかになった。また、後記実施例に示すように、ストマチンの欠失変異体として、ストマチンの５６〜２３４番目のアミノ散配列からなる1511-N3 (56-234)、同１６８〜２６６番目のアミノ散配列からなる1511-C1 (168-266)、及び同５６〜１６５番目のアミノ散配列からなる1511-N2 (56-165))について結晶化を行ったが、これら欠失変異体1511-C1 (168-266)、1511-N2 (56-165)、1511-N3 (56-234)のうちで1511-N3 (56-234)のみが結晶化できた理由は、1511-N3のみがβ1とβ6の両方を含むためであった。図1の一次配列アライメントはβ1とβ6の二次構造が全てのストマチンオルソログに保存されていることを表している。従って、β1からβ6までを含む可溶性ドメインを最小単位とする欠失変異体を構築するならば、全てのストマチンのオルソログにおいてStoCD結晶化の成功率が飛躍的に高まることが予測される。つまり、結晶化に必須な一つ目の条件は欠失変異体の中に必ずβ1からβ6までの領域が含まれねばならない。
【００２９】
また、図4Cは結晶パッキングと結晶学的対称分子を示す。興味深いことにA鎖のα-ヘリカル構造体（α5）が結晶学的対称分子中のC鎖のα5と逆平行のCoiled coil構造を形成する。この逆平行のCoiled coil構造を形成する二本のα5は偽2回対称軸で関係付けられている。α5は7残基繰り返しパターンを有しており、ヘリカル輪(helical wheel)分析ではaとdポジションには疎水性アミノ酸残基が集まり、cとfとgポジションには荷電アミノ酸残基と極性アミノ酸残基が集まっている。つまり、長鎖α-ヘリカル剛体の片面が疎水性になっており、そこが逆平行に合わさりCoiled coil構造の界面を形成している。一方、Coiled coil構造の表面全体は親水性に富み、構造の安定化に貢献している。高い含水率（71％）にもかかわらずPhStoCDが結晶化した理由は、この逆平行Coiled coil構造が結晶格子の安定形成に大きく寄与したためである。よって、結晶化に必須な二つ目の条件は欠失変異体の中に必ずα5領域が含まれねばならない。
【００３０】
さらに、図5AとBはPhStoCD 3量体を空間充填モデルで表し、その表面を塩基性アミノ酸側鎖を青色、酸性アミノ酸側鎖を赤色、疎水性アミノ酸側鎖を白色で表示した。図5Aは三角形構造体を斜め上から見たステレオ図を表し、図5Bは三角形構造体下面から見たステレオ図を示す。図5CはPhStoCDを空間充填モデルで現し、三角形構造体を斜め上から見たステレオ図に、極性アミノ酸残基を緑色で、疎水性アミノ酸側鎖を白色で区別した。これらの図から三角形構造体上面が下面に比べ疎水性残基の割合が高く、上面で生体膜に接すると考えられる。また、α-ヘリカル構造体（α5）が三角形構造体上面に平行になるまで持ち上がり、そのときα-ヘリカル構造体の生体膜に接する面に一列に整列する塩基性アミノ酸側鎖がリン脂質等の陰電荷物質と相互作用し生体膜の曲率を変化させる機構が予測された。この様に、PhStoCD三次元構造から、該タンパク質の複合体形成に関与するアミノ酸残基の配置が明らかとなり、それによって機能変換型のStoCDを得るために変異させるべき残基を絞り込むことができる。すなわち、部位特異的変異によって特定の残基を任意のアミノ酸に置換し、得られた変異体について機能の検討を行って、ストマチン分子の知覚センサーやイオンチャネル等機能分子への制御機能を精査すること、もしくはストマチンの生体膜機能制御能を阻害或いは修飾する薬剤を開発することが可能となる。
以下に本発明の実施例を示すが、本発明は特にこれらの実施例により限定されるものではない。
【実施例】
【００３１】
実施例1 
(1) Pyrococcus horikoshii JCM９９７４の培養方法
13.5ｇの食塩、4gのNa2SO4, 0.7 gのKCl, 0.2g のNaHCO3、0.1gのKBr、30 mg のH3BO3、10gのMgCl2・6H2O、1.5g のCaCl2、25mgのSrCl2、1.0mlのレザスリン溶液（0.2g/L）、1.0gの酵母エキス、5gのバクトペプトンを1Lに溶かし、この溶液のpHを6.8に調整し加圧殺菌した。ついで、乾熱滅菌した元素硫黄を0.2％となるように加え、この培地をアルゴンで飽和して嫌気性とした後、JCM９９７４を植菌した。培地が嫌気性となったか否かはNa2S溶液を加えて、培養液中でNa2Sによるレザスリン溶液のピンク色が着色しないことにより確認した。この培養液を95℃で２〜4日培養し、その後遠心分離し集菌した。
【００３２】
（2）P. horikoshii 染色体ＤＮＡの調整
JCM９９７４の染色体DNAは以下の方法により調製した。培養終了後5000rpm、10分間の遠心分離により菌体を集菌する。菌体を10mM Tris(pH 7.5) 1mM EDTA 溶液で２回洗浄後InCert Agarose（FMC社製）ブロック中に封入する。このブロックを１％N-lauroylsarcosine, 1mg/mlプロテアーゼK溶液中で処理することにより、染色体DNAはAgaroseブロック中に分離調製される。
【００３３】
実施例2
（１）ストマチン欠失変異体をコードするＤＮＡ断片及び発現ベクターの取得
PH1511pのアミノ酸一次配列に基づきChau-Fasman法により二次構造予測を行い、その結果に基づきドメイン境界領域を判定し、図2Bに示した7種の領域をコ−ドするDNA断片を遺伝子増幅法（PCR法）で得た。
ＰＣＲは上記実施例1で得たP. horikoshii 染色体ＤＮＡを鋳型DNAとし、以下の7組のUpperプライマーとLowerプライマーを用いてPCR反応を行った。
【００３４】
1511-Nの増幅：
Upper primer  2（配列番号７）
5’-TGACTGGTGCATATGGTTTTAGACGTCCCAGTACAG-3’（下線部はNdeIサイトを示す）
Lower primer  2（配列番号８）
5’-CCCAAAGAGCTCATTGCTCTTATCGCCGGCGACATC-3’（下線部はXhoIサイトを示す）
1511-Cの増幅：
Upper primer  5（配列番号９）
5’-TGACTGGTGCATATGAGGATAACGCTAGCTGAGGCC-3’（下線部はNdeIサイトを示す）
Lower primer  4（配列番号１０）
5’-CCCAAAGAGCTCCTTTTCTTCTTCCTTCTTCTTCATGT-3’（下線部はXhoIサイトを示す）
1511-C1の増幅：
Upper primer  4（配列番号１１）
5’-TGACTGGTGCATATGTTACCGGCTGGAATGCAAAAA-3’（下線部はNdeIサイトを示す）
Lower primer  4（配列番号１０）
5’-CCCAAAGAGCTCCTTTTCTTCTTCCTTCTTCTTCATGT-3’（下線部はXhoIサイトを示す）
1511-C2の増幅：
Upper primer  4（配列番号１１）
5’-TGACTGGTGCATATGTTACCGGCTGGAATGCAAAAA-3’（下線部はNdeIサイトを示す）
Lower primer  3（配列番号１２）
5’-CCCAAAGAGCTCTTCCGCTGCATCCGATAAACT-3’（下線部はXhoIサイトを示す）
1511-C3の増幅：
Upper primer  5（配列番号９）
5’-TGACTGGTGCATATGAGGATAACGCTAGCTGAGGCC-3’（下線部はNdeIサイトを示す）
Lower primer  3（配列番号１２）
5’-CCCAAAGAGCTCTTCCGCTGCATCCGATAAACT-3’（下線部はXhoIサイトを示す）
1511-N1の増幅：
Upper primer  3（配列番号１３）
5’-TGACTGGTGCATATGGTACAGGAAACGATAACAAAA-3’（下線部はNdeIサイトを示す）
Lower primer  1（配列番号１４）
5’-CCCAAAGAGCTCATCCTTAATCTCTACAGCGGT-3’（下線部はXhoIサイトを示す）
1511-N2の増幅：
Upper primer  1（配列番号１５）
5’-TGACTGGTGCATATGATCTTCGAAAAGGCCGTTATC-3’（下線部はNdeIサイトを示す）
Lower primer  1（配列番号１４）
5’-CCCAAAGAGCTCATCCTTAATCTCTACAGCGGT-3’（下線部はXhoIサイトを示す）
1511-N3の増幅：
Upper primer  1（配列番号１５）
5’-TGACTGGTGCATATGATCTTCGAAAAGGCCGTTATC-3’（下線部はNdeIサイトを示す）
Lower primer  2（配列番号８）
5’-CCCAAAGAGCTCATTGCTCTTATCGCCGGCGACATC-3’（下線部はXhoIサイトを示す）
【００３５】
以下に7種のクローン名を示し、カッコ内に領域の最初と最後の残基番号を付した。1511-N (69-234)、1511-C (189-266)、1511-C1 (168-266)、1511-C2 (168-256)、1511-C3 (189-256)、1511-N1 (74-165)、1511-N2 (56-165)、1511-N3 (56-234)。
上記PCR法で用いられたUpperプライマーとLowerプライマーには各々制限酵素Nde Iサイトと制限酵素Xho Iサイトがデザインされているので、増幅したDNA断片はNde IとXhoで消化し、発現ベクターpET-21b(+)（ノバージェン）のNde IとXhoサイトに挿入し、得られた発現ベクターを各々、pET-21b/1511-N、pET-21b/1511-C、pET-21b/1511-C1、pET-21b/1511-C2、pET-21b/1511-C3、pET-21b/1511-N1、pET-21b/1511-N2、pET-21b/1511-N3と命名した。なお、この発現ベクターを用いた組換えタンパク質のN-末には一つの初発メチオニン残基とC-末にはLEHHHHHHのヘキサヒスチジンタグ配列が余分に付加されている。
【００３６】
次に上記の７種の発現ベクターで大腸菌E. coli BL21 (DE3) Codon-Plus RIL株（ストラタジーン）を形質転換し、得られた組換え体はアンピシリンを含む2YT培地（２リットル）で660ｎｍの吸収が0.4に達するまで37℃で培養した後、IPTG（Isopropyl-b-D-thiogalactopyranoside）を1 mMになるように加え、37℃で4時間培養した。培養後遠心分離（6,000ｒｐｍ，20min）で集菌し、-20℃で保存した。
上記７種の発現ベクターのうち、代表例となるpET-21b/1511-N3で発現される融合タンパク質PhStoCDのアミノ酸配列と遺伝子配列は、以下に示す。形質転換体E. coli BL21 (DE3) Codon-Plus RIL/ pET-21b/1511-N3は独立行政法人産業技術総合研究所特許生物寄託センター（茨城県つくば市東1-1-1  つくばセンター 中央第6）に平成19年12月7日に寄託され、寄託番号FERM P-21463を与えられた。
【００３７】
［化１］
PhStoCDのアミノ酸配列（配列番号１６）
MIFEKAVIVDLRTQVLDVPVQETITKDNVPVRVNAVVYFRVVDPVKAVTQVKNYIMATSQISQTTLRSVIGQAHLDELLSERDKLNMQLQRIIDEATDPWGIKVTAVEIKDVELPAGMQKAMARQAEAERERRARITLAEAERQAAEKLREAAEIISEHPMALQLRTLQTISDVAGDKSN LEHHHHHH
PhStoCDの遺伝子配列（配列番号１７）
atgatcttcgaaaaggccgttatcgtagatttgagaactcaagttttagacgtcccagtacaggaaacgataacaaaagataacgttcccgttagggtaaatgcggtagtttactttagagtcgttgatcccgttaaagccgtgactcaggttaagaactacataatggctacctcgcagatatcgcaaacaaccctaaggagcgtaataggtcaagcccacttggatgaactattaagcgagagggataaactgaatatgcaacttcagaggatcatcgatgaagcaaccgatccctggggaataaaagttaccgctgtagagattaaggatgtagagttaccggctggaatgcaaaaagccatggcaagacaggcagaagctgaaagggagaggagagcaaggataacgctagctgaggccgagagacaggccgctgaaaagcttagggaagctgcagagataataagtgaacatccaatggccttacaactaagaacccttcaaacgataagcgatgtcgccggcgataagagcaatctcgagcaccaccaccaccaccac
【００３８】
（２）発現ベクターpET-21b/1511-N3を用いたセレノメチオニン誘導体PhStoCDの発現
発現ベクターpET-21b/1511-N3で大腸菌メチオニン要求株E. coli BL21 (DE3) Codon-Plus RIL-X （ストラタジーン）を形質転換し、得られた組換え体はメチオニンを含まないLeMaster’sスタート培地5 ml（50mg/literのセレノメチオニン、1mM MgSO4、27.5μM FeSO4、0.8% (W/V)のグルコース、2%の2YT培地、50μg/mlのアンピシリンを含む）で37℃、7.5時間middle-log phaseまで培養した。その後、前記種菌をメチオニンを含まないLeMaster’s醗酵培地200ml（50mg/literのセレノメチオニン、1mM MgSO4、27.5μM FeSO4、2 mg/literのチアミン、0.8% (W/V)のラクトース、50μg/mlのアンピシリンを含む）に移植し、37℃で13時間培養した(LeMaster and Richards, 1985, Biochemistry, 24,7263-7268)。培養後遠心分離（6,000 rpm，20min）で集菌し、-20℃で保存した。
【００３９】
（３）ストマチン欠失変異体の精製
冷凍保存した菌体に２倍量の50mMトリス塩酸緩衝液（pH7.5）を加え懸濁液を得た。このトリス塩酸緩衝液には0.15M NaCl、1錠のプロテアーゼ阻害剤（Complete EDTA-free, Roche社製）、0.5mgのDNase 1（シグマ社製）が予め加えられている。得られた懸濁液を超音波破砕し、遠心分離(15,000 x g、20分)により上清液を得た。この上清液を、85℃か65℃で10分間加熱し、遠心上清を0.3M NaCl、5mMイミダゾールで平衡化した Ni-カラム（Novagen,  His・Bind metal chelation resin）に懸け、30mMイミダゾールを含む緩衝液による洗浄後、目的タンパク質は500mMイミダゾールを含む緩衝液で溶出された。回収されたタンパク質はセントリプレップ-10 或いはセントリコン-10  (アミコン社)で濃縮し、さらに50mMトリス塩酸緩衝液（pH8.5）で平衡化した陰イオン交換Q-Sepharoseカラム（アマシャム  バイオサイエンス）に添加し、0-0.5M NaClの塩勾配で溶出した。目的とするストマチン欠失変異体を含む分画を集め4℃で保存した。タンパク質濃度はCoomassie protein assay 試薬 (Pierce)で測定した。
【００４０】
その結果、上記7種のストマチン欠失変異体の内で2種、1511-N2 (56-165)、1511-N3 (56-234)のみが10分間加熱処理に耐性を示し、単離精製できることが明らかになった。ただし、1511-N3 (56-234)は85℃まで熱耐性で、1511-N2 (56-165)は65℃まで熱耐性であった。さらに、上記請求項［００１８］で得た2種の精製標品1511-N2 (56-165)と1511-N3 (56-234)を各々、0.15 M NaClを含む50mMトリス塩酸緩衝液（pH7.5）で平衡化したゲルろ過カラムSuperose 12に添加し、同緩衝液で溶出すると単一ピークとして回収でき、均一な分子形態を有すると確認された。よって、欠失変異体1511-N2 (56-165)は1511-N3 (56-234)は結晶化の素材として用いうると判定された。
【００４１】
実施例２
実施例１で精製された、欠失変異体1511-N2 (56-165)と1511-N3 (56-234)の各々について濃縮後50mMトリス塩酸緩衝液（pH7.5）に溶解し、ハンギングドロップ法による結晶化を行った。
タンパク質濃度が10 mg/mlで、沈殿剤溶液として、20% 2-メチル-2,4-ペンタンジオール(MPD)、0.2 M硫酸アンモニウム、0.1 M HEPES-NaOH (pH 7.5)を用い、ｚPhStoCDと上記沈殿剤の1:1混液に1,5-diaminopentane-HClを終濃度6%となる様加えた時に、1511-N3 (56-234)について0.30×0.20×0.05mmの板状結晶が得られた（図3）。1511-N2 (56-165)の場合は、結晶が得られなかった。
【００４２】
実施例３
Ｘ線回折装置ＳＭＡＲＴ６０００(ブルカーＡＸＳ社)を用いて、実施例２により得られた1511-N3 (56-234)の結晶のＸ線回折強度を測定した。
得られたＸ線強度データのパターンにより、当該結晶は、単斜晶系に属しており、空間群がＣ２、格子定数がa＝142.6Å、ｂ＝137.2Å、ｃ＝58.5Å、β＝107.6°である。そして、計算により導き出される該結晶の溶媒含有率は71%であり、非対称単位内に欠失変異体を１分子含むものとされた。また、前記データの分解能は3.1Åであり、側鎖の向きも含めた三次元構造の決定が可能なレベルにあった。
次に、multiwavelength anomalous dispersion法（MAD法）を用いて、上記のようにして得られたＸ線回折強度データに基づいて結晶を構成する分子の電子密度図を導きだし、さらに、プログラムREFMAC5による精密化と、プログラムCOOTを用いた三次元グラフィックスによる修正作業を行った。精密化の指標となるＲ因子の値は20％以下になることが目標とされており、1511-N3 (56-234)の場合は、Ｒ因子が19.8％まで下がった時点で精密化を終えた。その結果得られた、結晶の原子座標を表1に示す。また、このような過程を経て得られたPhStoCDの三次元構造を図4と5に示す。
【００４３】
［表1］PhStoCD結晶の原子座標
HEADER    ----                                    XX-XXX-XX   xxxx              
COMPND    ---                                                                   
REMARK   3
REMARK   3 REFINEMENT.
REMARK   3   PROGRAM     : REFMAC 5.2.0019
REMARK   3   AUTHORS     : MURSHUDOV,VAGIN,DODSON
REMARK   3
REMARK   3    REFINEMENT TARGET : MAXIMUM LIKELIHOOD
REMARK   3
REMARK   3  DATA USED IN REFINEMENT.
REMARK   3   RESOLUTION RANGE HIGH (ANGSTROMS) :   3.20
REMARK   3   RESOLUTION RANGE LOW  (ANGSTROMS) :  19.97
REMARK   3   DATA CUTOFF            (SIGMA(F)) : NONE
REMARK   3   COMPLETENESS FOR RANGE        (%) :  99.71
REMARK   3   NUMBER OF REFLECTIONS             :   15824
REMARK   3
REMARK   3  FIT TO DATA USED IN REFINEMENT.
REMARK   3   CROSS-VALIDATION METHOD          : THROUGHOUT
REMARK   3   FREE R VALUE TEST SET SELECTION  : RANDOM
REMARK   3   R VALUE     (WORKING + TEST SET) : 0.20446
REMARK   3   R VALUE            (WORKING SET) :  0.19774
REMARK   3   FREE R VALUE                     :  0.26234
REMARK   3   FREE R VALUE TEST SET SIZE   (%) : 10.2
REMARK   3   FREE R VALUE TEST SET COUNT      :  1792
REMARK   3
REMARK   3  FIT IN THE HIGHEST RESOLUTION BIN.
REMARK   3   TOTAL NUMBER OF BINS USED           :      20
REMARK   3   BIN RESOLUTION RANGE HIGH           :    3.201
REMARK   3   BIN RESOLUTION RANGE LOW            :    3.282
REMARK   3   REFLECTION IN BIN     (WORKING SET) :     1120
REMARK   3   BIN COMPLETENESS (WORKING+TEST) (%) :    96.34
REMARK   3   BIN R VALUE           (WORKING SET) :    0.294
REMARK   3   BIN FREE R VALUE SET COUNT          :      117
REMARK   3   BIN FREE R VALUE                    :    0.345
REMARK   3
REMARK   3  NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.
REMARK   3   ALL ATOMS                :     3733
REMARK   3
REMARK   3  B VALUES.
REMARK   3   FROM WILSON PLOT           (A**2) : NULL
REMARK   3   MEAN B VALUE      (OVERALL, A**2) : 101.114
REMARK   3   OVERALL ANISOTROPIC B VALUE.
REMARK   3    B11 (A**2) :    -0.58
REMARK   3    B22 (A**2) :     0.11
REMARK   3    B33 (A**2) :     0.29
REMARK   3    B12 (A**2) :     0.00
REMARK   3    B13 (A**2) :    -0.30
REMARK   3    B23 (A**2) :     0.00
REMARK   3
REMARK   3  ESTIMATED OVERALL COORDINATE ERROR.
REMARK   3   ESU BASED ON R VALUE                            (A):   1.343
REMARK   3   ESU BASED ON FREE R VALUE                       (A):   0.423
REMARK   3   ESU BASED ON MAXIMUM LIKELIHOOD                 (A):   0.316
REMARK   3   ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2):  18.023
REMARK   3
REMARK   3 CORRELATION COEFFICIENTS.
REMARK   3   CORRELATION COEFFICIENT FO-FC      :   0.954
REMARK   3   CORRELATION COEFFICIENT FO-FC FREE :   0.917
REMARK   3
REMARK   3  RMS DEVIATIONS FROM IDEAL VALUES        COUNT    RMS    WEIGHT
REMARK   3   BOND LENGTHS REFINED ATOMS        (A):  3770 ; 0.022 ; 0.022
REMARK   3   BOND ANGLES REFINED ATOMS   (DEGREES):  5105 ; 2.176 ; 1.970
REMARK   3   TORSION ANGLES, PERIOD 1    (DEGREES):   469 ; 7.732 ; 5.000
REMARK   3   TORSION ANGLES, PERIOD 2    (DEGREES):   175 ;39.510 ;24.514
REMARK   3   TORSION ANGLES, PERIOD 3    (DEGREES):   728 ;24.547 ;15.000
REMARK   3   TORSION ANGLES, PERIOD 4    (DEGREES):    38 ;21.756 ;15.000
REMARK   3   CHIRAL-CENTER RESTRAINTS       (A**3):   624 ; 0.124 ; 0.200
REMARK   3   GENERAL PLANES REFINED ATOMS      (A):  2756 ; 0.006 ; 0.020
REMARK   3   NON-BONDED CONTACTS REFINED ATOMS (A):  1735 ; 0.282 ; 0.200
REMARK   3   NON-BONDED TORSION REFINED ATOMS  (A):  2551 ; 0.330 ; 0.200
REMARK   3   H-BOND (X...Y) REFINED ATOMS      (A):   144 ; 0.151 ; 0.200
REMARK   3   SYMMETRY VDW REFINED ATOMS        (A):    59 ; 0.246 ; 0.200
REMARK   3   SYMMETRY H-BOND REFINED ATOMS     (A):     5 ; 0.286 ; 0.200
REMARK   3
REMARK   3  ISOTROPIC THERMAL FACTOR RESTRAINTS.     COUNT   RMS    WEIGHT
REMARK   3   MAIN-CHAIN BOND REFINED ATOMS  (A**2):  2455 ; 3.836 ; 2.000
REMARK   3   MAIN-CHAIN ANGLE REFINED ATOMS (A**2):  3865 ; 5.889 ; 3.000
REMARK   3   SIDE-CHAIN BOND REFINED ATOMS  (A**2):  1468 ; 4.393 ; 2.000
REMARK   3   SIDE-CHAIN ANGLE REFINED ATOMS (A**2):  1240 ; 7.173 ; 3.000
REMARK   3
REMARK   3  NCS RESTRAINTS STATISTICS
REMARK   3   NUMBER OF NCS GROUPS : NULL
REMARK   3
REMARK   3
REMARK   3  TLS DETAILS
REMARK   3   NUMBER OF TLS GROUPS  : NULL
REMARK   3
REMARK   3
REMARK   3  BULK SOLVENT MODELLING.
REMARK   3   METHOD USED :  MASK
REMARK   3   PARAMETERS FOR MASK CALCULATION
REMARK   3   VDW PROBE RADIUS   :   1.40
REMARK   3   ION PROBE RADIUS   :   0.80
REMARK   3   SHRINKAGE RADIUS   :   0.80
REMARK   3
REMARK   3  OTHER REFINEMENT REMARKS:
REMARK   3  HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
REMARK   3
CRYST1  142.553  137.150   58.544  90.00 107.61  90.00 C 1 2 1                  
SCALE1      0.007015  0.000000  0.002227        0.00000                         
SCALE2      0.000000  0.007291  0.000000        0.00000                         
SCALE3      0.000000  0.000000  0.017921        0.00000                         
ATOM      1  N   MET A  55      -2.982 -12.100   5.268  1.00123.19           N
ATOM      2  CA  MET A  55      -3.693 -11.948   6.567  1.00128.23           C
ATOM      3  CB  MET A  55      -2.892 -12.599   7.689  1.00131.24           C
ATOM      4  CG  MET A  55      -2.856 -14.088   7.623  1.00135.69           C
ATOM      5  SD  MET A  55      -1.219 -14.661   8.098  1.00138.97           S
ATOM      6  CE  MET A  55      -0.718 -15.598   6.601  1.00136.82           C
ATOM      7  C   MET A  55      -3.865 -10.503   6.939  1.00121.68           C
ATOM      8  O   MET A  55      -3.695  -9.611   6.120  1.00122.22           O
ATOM      9  N   ILE A  56      -4.187 -10.292   8.207  1.00115.86           N
ATOM     10  CA  ILE A  56      -4.158  -8.972   8.803  1.00113.94           C
ATOM     11  CB  ILE A  56      -5.598  -8.539   9.322  1.00114.38           C
ATOM     12  CG1 ILE A  56      -6.313  -7.720   8.228  1.00117.40           C
ATOM     13  CD1 ILE A  56      -7.834  -7.467   8.477  1.00120.59           C
ATOM     14  CG2 ILE A  56      -5.562  -7.723  10.635  1.00111.58           C
ATOM     15  C   ILE A  56      -2.987  -8.836   9.816  1.00109.22           C
ATOM     16  O   ILE A  56      -2.922  -9.509  10.854  1.00106.14           O
ATOM     17  N   PHE A  57      -2.040  -7.975   9.497  1.00103.84           N
ATOM     18  CA  PHE A  57      -0.935  -7.809  10.410  1.00104.69           C
ATOM     19  CB  PHE A  57       0.345  -7.611   9.624  1.00102.52           C
ATOM     20  CG  PHE A  57       0.806  -8.842   8.946  1.00 99.50           C
ATOM     21  CD1 PHE A  57       0.537  -9.040   7.595  1.00100.19           C
ATOM     22  CE1 PHE A  57       0.980 -10.169   6.948  1.00100.87           C
ATOM     23  CZ  PHE A  57       1.695 -11.137   7.680  1.00103.48           C
ATOM     24  CE2 PHE A  57       1.969 -10.952   9.051  1.00 99.02           C
ATOM     25  CD2 PHE A  57       1.516  -9.812   9.662  1.00 98.96           C
ATOM     26  C   PHE A  57      -1.126  -6.694  11.439  1.00105.73           C
ATOM     27  O   PHE A  57      -1.928  -5.780  11.209  1.00107.60           O
ATOM     28  N   GLU A  58      -0.372  -6.772  12.547  1.00103.10           N
ATOM     29  CA  GLU A  58      -0.413  -5.787  13.625  1.00104.39           C
ATOM     30  CB  GLU A  58      -1.515  -6.173  14.613  1.00108.50           C
ATOM     31  CG  GLU A  58      -1.104  -7.227  15.638  1.00115.42           C
ATOM     32  CD  GLU A  58      -2.131  -7.422  16.742  1.00116.63           C
ATOM     33  OE1 GLU A  58      -3.235  -6.820  16.647  1.00117.74           O
ATOM     34  OE2 GLU A  58      -1.826  -8.195  17.695  1.00124.71           O
ATOM     35  C   GLU A  58       0.927  -5.650  14.357  1.00 98.62           C
ATOM     36  O   GLU A  58       1.594  -6.649  14.621  1.00 97.71           O
ATOM     37  N   LYS A  59       1.314  -4.428  14.713  1.00 95.26           N
ATOM     38  CA  LYS A  59       2.625  -4.231  15.354  1.00 96.97           C
ATOM     39  CB  LYS A  59       2.874  -2.763  15.711  1.00103.94           C
ATOM     40  CG  LYS A  59       3.193  -1.914  14.493  1.00113.56           C
ATOM     41  CD  LYS A  59       3.777  -0.560  14.827  1.00118.30           C
ATOM     42  CE  LYS A  59       4.036   0.168  13.503  1.00122.10           C
ATOM     43  NZ  LYS A  59       5.128   1.171  13.695  1.00124.18           N
ATOM     44  C   LYS A  59       2.803  -5.062  16.598  1.00 93.94           C
ATOM     45  O   LYS A  59       1.981  -5.030  17.463  1.00 98.65           O
ATOM     46  N   ALA A  60       3.884  -5.806  16.696  1.00 93.21           N
ATOM     47  CA  ALA A  60       4.129  -6.641  17.866  1.00 92.29           C
ATOM     48  CB  ALA A  60       5.242  -7.641  17.596  1.00 93.65           C
ATOM     49  C   ALA A  60       4.535  -5.763  19.013  1.00 92.18           C
ATOM     50  O   ALA A  60       5.349  -4.847  18.832  1.00 97.33           O
ATOM     51  N   VAL A  61       4.001  -6.048  20.197  1.00 85.99           N
ATOM     52  CA  VAL A  61       4.431  -5.315  21.356  1.00 83.18           C
ATOM     53  CB  VAL A  61       3.292  -5.054  22.365  1.00 80.11           C
ATOM     54  CG1 VAL A  61       3.859  -4.442  23.685  1.00 80.63           C
ATOM     55  CG2 VAL A  61       2.250  -4.139  21.758  1.00 77.54           C
ATOM     56  C   VAL A  61       5.589  -6.031  22.001  1.00 85.16           C
ATOM     57  O   VAL A  61       5.409  -6.787  22.920  1.00 88.16           O
ATOM     58  N   ILE A  62       6.797  -5.786  21.544  1.00 90.01           N
ATOM     59  CA  ILE A  62       7.945  -6.362  22.253  1.00 96.36           C
ATOM     60  CB  ILE A  62       8.869  -7.068  21.243  1.00101.89           C
ATOM     61  CG1 ILE A  62       9.596  -6.057  20.310  1.00105.50           C
ATOM     62  CD1 ILE A  62       8.731  -5.442  19.118  1.00107.61           C
ATOM     63  CG2 ILE A  62       8.052  -8.071  20.463  1.00103.10           C
ATOM     64  C   ILE A  62       8.737  -5.409  23.214  1.00 95.87           C
ATOM     65  O   ILE A  62       8.761  -4.175  23.021  1.00 92.77           O
ATOM     66  N   VAL A  63       9.383  -5.983  24.236  1.00 94.09           N
ATOM     67  CA  VAL A  63      10.326  -5.219  25.070  1.00 96.79           C
ATOM     68  CB  VAL A  63      11.311  -6.115  25.805  1.00 93.42           C
ATOM     69  CG1 VAL A  63      12.508  -5.305  26.178  1.00 91.34           C
ATOM     70  CG2 VAL A  63      10.680  -6.729  27.065  1.00 94.77           C
ATOM     71  C   VAL A  63      11.166  -4.236  24.241  1.00101.15           C
ATOM     72  O   VAL A  63      11.694  -4.590  23.180  1.00106.66           O
ATOM     73  N   ASP A  64      11.289  -3.001  24.700  1.00101.67           N
ATOM     74  CA  ASP A  64      12.005  -2.040  23.890  1.00101.76           C
ATOM     75  CB  ASP A  64      11.403  -0.658  24.024  1.00100.75           C
ATOM     76  CG  ASP A  64      10.286  -0.405  23.003  1.00103.19           C
ATOM     77  OD1 ASP A  64      10.502  -0.679  21.791  1.00104.25           O
ATOM     78  OD2 ASP A  64       9.198   0.097  23.406  1.00102.03           O
ATOM     79  C   ASP A  64      13.499  -2.052  24.170  1.00104.07           C
ATOM     80  O   ASP A  64      13.925  -2.251  25.298  1.00107.65           O
ATOM     81  N   LEU A  65      14.286  -1.848  23.117  1.00104.02           N
ATOM     82  CA  LEU A  65      15.740  -1.824  23.198  1.00 97.77           C
ATOM     83  CB  LEU A  65      16.321  -2.424  21.940  1.00 86.12           C
ATOM     84  CG  LEU A  65      16.897  -3.811  21.930  1.00 75.03           C
ATOM     85  CD1 LEU A  65      16.204  -4.680  22.885  1.00 76.10           C
ATOM     86  CD2 LEU A  65      16.754  -4.326  20.548  1.00 74.00           C
ATOM     87  C   LEU A  65      16.184  -0.385  23.257  1.00104.67           C
ATOM     88  O   LEU A  65      16.971  -0.016  24.120  1.00107.99           O
ATOM     89  N   ARG A  66      15.702   0.426  22.320  1.00108.86           N
ATOM     90  CA  ARG A  66      15.960   1.851  22.387  1.00115.52           C
ATOM     91  CB  ARG A  66      16.562   2.396  21.081  1.00117.96           C
ATOM     92  CG  ARG A  66      18.042   2.791  21.220  1.00122.96           C
ATOM     93  CD  ARG A  66      18.762   2.994  19.857  1.00123.31           C
ATOM     94  NE  ARG A  66      20.214   2.829  20.018  1.00127.27           N
ATOM     95  CZ  ARG A  66      21.153   3.146  19.127  1.00126.16           C
ATOM     96  NH1 ARG A  66      20.853   3.673  17.944  1.00123.54           N
ATOM     97  NH2 ARG A  66      22.423   2.932  19.441  1.00129.08           N
ATOM     98  C   ARG A  66      14.672   2.553  22.724  1.00113.79           C
ATOM     99  O   ARG A  66      13.599   2.033  22.453  1.00115.51           O
ATOM    100  N   THR A  67      14.800   3.731  23.323  1.00111.22           N
ATOM    101  CA  THR A  67      13.682   4.619  23.599  1.00106.84           C
ATOM    102  CB  THR A  67      14.230   5.984  23.945  1.00105.80           C
ATOM    103  OG1 THR A  67      14.870   5.917  25.234  1.00107.04           O
ATOM    104  CG2 THR A  67      13.116   7.053  23.925  1.00103.71           C
ATOM    105  C   THR A  67      12.713   4.793  22.446  1.00105.66           C
ATOM    106  O   THR A  67      13.136   5.112  21.370  1.00112.07           O
ATOM    107  N   GLN A  68      11.425   4.559  22.677  1.00104.35           N
ATOM    108  CA  GLN A  68      10.357   4.999  21.778  1.00105.29           C
ATOM    109  CB  GLN A  68       9.169   4.061  21.897  1.00108.36           C
ATOM    110  CG  GLN A  68       9.175   2.801  20.996  1.00115.39           C
ATOM    111  CD  GLN A  68       7.716   2.200  20.852  1.00115.36           C
ATOM    112  OE1 GLN A  68       6.922   2.657  20.009  1.00114.30           O
ATOM    113  NE2 GLN A  68       7.375   1.204  21.701  1.00113.22           N
ATOM    114  C   GLN A  68       9.919   6.456  22.119  1.00 97.67           C
ATOM    115  O   GLN A  68      10.075   6.906  23.238  1.00 98.30           O
ATOM    116  N   VAL A  69       9.365   7.184  21.159  1.00 88.68           N
ATOM    117  CA  VAL A  69       9.076   8.601  21.331  1.00 82.33           C
ATOM    118  CB  VAL A  69       9.853   9.411  20.299  1.00 79.08           C
ATOM    119  CG1 VAL A  69       9.443  10.824  20.342  1.00 78.58           C
ATOM    120  CG2 VAL A  69      11.289   9.309  20.529  1.00 80.81           C
ATOM    121  C   VAL A  69       7.662   8.871  20.915  1.00 83.62           C
ATOM    122  O   VAL A  69       7.351   8.621  19.766  1.00 86.43           O
ATOM    123  N   LEU A  70       6.813   9.442  21.763  1.00 82.49           N
ATOM    124  CA  LEU A  70       5.463   9.777  21.298  1.00 85.28           C
ATOM    125  CB  LEU A  70       4.466   8.958  22.092  1.00 88.94           C
ATOM    126  CG  LEU A  70       3.210   9.572  22.696  1.00 93.20           C
ATOM    127  CD1 LEU A  70       2.181  10.062  21.670  1.00 92.70           C
ATOM    128  CD2 LEU A  70       2.625   8.472  23.582  1.00 96.56           C
ATOM    129  C   LEU A  70       5.174  11.265  21.401  1.00 85.17           C
ATOM    130  O   LEU A  70       5.572  11.848  22.398  1.00 89.86           O
ATOM    131  N   ASP A  71       4.515  11.872  20.393  1.00 84.23           N
ATOM    132  CA  ASP A  71       4.127  13.310  20.431  1.00 86.52           C
ATOM    133  CB  ASP A  71       3.974  13.938  19.051  1.00 93.20           C
ATOM    134  CG  ASP A  71       5.275  14.111  18.316  1.00102.44           C
ATOM    135  OD1 ASP A  71       6.215  14.799  18.781  1.00107.59           O
ATOM    136  OD2 ASP A  71       5.342  13.588  17.196  1.00108.42           O
ATOM    137  C   ASP A  71       2.776  13.546  21.067  1.00 89.06           C
ATOM    138  O   ASP A  71       1.750  13.092  20.539  1.00 94.99           O
ATOM    139  N   VAL A  72       2.754  14.321  22.147  1.00 86.01           N
ATOM    140  CA  VAL A  72       1.496  14.772  22.740  1.00 83.28           C
ATOM    141  CB  VAL A  72       1.707  15.154  24.204  1.00 80.26           C
ATOM    142  CG1 VAL A  72       0.364  15.206  24.929  1.00 79.18           C
ATOM    143  CG2 VAL A  72       2.606  14.144  24.869  1.00 76.64           C
ATOM    144  C   VAL A  72       0.869  15.959  21.946  1.00 84.16           C
ATOM    145  O   VAL A  72       1.470  17.022  21.895  1.00 84.06           O
ATOM    146  N   PRO A  73      -0.347  15.783  21.342  1.00 83.29           N
ATOM    147  CA  PRO A  73      -0.952  16.813  20.468  1.00 82.86           C
ATOM    148  CB  PRO A  73      -2.343  16.238  20.164  1.00 77.39           C
ATOM    149  CG  PRO A  73      -2.597  15.233  21.229  1.00 71.13           C
ATOM    150  CD  PRO A  73      -1.259  14.626  21.476  1.00 79.33           C
ATOM    151  C   PRO A  73      -1.134  18.120  21.190  1.00 85.50           C
ATOM    152  O   PRO A  73      -1.296  18.115  22.413  1.00 91.34           O
ATOM    153  N   VAL A  74      -1.143  19.223  20.457  1.00 87.55           N
ATOM    154  CA  VAL A  74      -1.276  20.552  21.076  1.00 90.02           C
ATOM    155  CB  VAL A  74      -1.381  21.589  19.971  1.00 90.13           C
ATOM    156  CG1 VAL A  74      -2.202  22.785  20.392  1.00 90.69           C
ATOM    157  CG2 VAL A  74      -0.006  21.989  19.544  1.00 94.24           C
ATOM    158  C   VAL A  74      -2.491  20.673  21.992  1.00 92.54           C
ATOM    159  O   VAL A  74      -3.539  20.159  21.668  1.00 96.33           O
ATOM    160  N   GLN A  75      -2.366  21.334  23.134  1.00 97.49           N
ATOM    161  CA  GLN A  75      -3.560  21.675  23.927  1.00102.40           C
ATOM    162  CB  GLN A  75      -3.482  21.084  25.306  1.00104.64           C
ATOM    163  CG  GLN A  75      -3.817  19.669  25.263  1.00114.87           C
ATOM    164  CD  GLN A  75      -3.067  18.914  26.296  1.00122.10           C
ATOM    165  OE1 GLN A  75      -2.845  19.408  27.425  1.00122.99           O
ATOM    166  NE2 GLN A  75      -2.646  17.698  25.930  1.00124.90           N
ATOM    167  C   GLN A  75      -3.774  23.154  24.074  1.00102.32           C
ATOM    168  O   GLN A  75      -2.812  23.914  24.131  1.00106.04           O
ATOM    169  N   GLU A  76      -5.026  23.578  24.154  1.00 99.42           N
ATOM    170  CA  GLU A  76      -5.268  24.953  24.534  1.00 99.36           C
ATOM    171  CB  GLU A  76      -6.363  25.559  23.694  1.00100.58           C
ATOM    172  CG  GLU A  76      -6.369  27.059  23.673  1.00105.20           C
ATOM    173  CD  GLU A  76      -7.494  27.616  22.808  1.00110.40           C
ATOM    174  OE1 GLU A  76      -8.697  27.346  23.134  1.00115.73           O
ATOM    175  OE2 GLU A  76      -7.176  28.328  21.817  1.00109.33           O
ATOM    176  C   GLU A  76      -5.712  24.902  25.966  1.00100.16           C
ATOM    177  O   GLU A  76      -6.592  24.134  26.286  1.00107.81           O
ATOM    178  N   THR A  77      -5.081  25.669  26.843  1.00 96.61           N
ATOM    179  CA  THR A  77      -5.552  25.776  28.201  1.00 94.67           C
ATOM    180  CB  THR A  77      -5.329  24.467  29.036  1.00 98.03           C
ATOM    181  OG1 THR A  77      -5.500  24.742  30.425  1.00102.52           O
ATOM    182  CG2 THR A  77      -3.953  23.884  28.860  1.00100.23           C
ATOM    183  C   THR A  77      -4.942  27.007  28.833  1.00 92.60           C
ATOM    184  O   THR A  77      -3.990  27.556  28.302  1.00 88.18           O
ATOM    185  N   ILE A  78      -5.533  27.430  29.950  1.00 93.64           N
ATOM    186  CA  ILE A  78      -5.203  28.679  30.641  1.00 94.14           C
ATOM    187  CB  ILE A  78      -6.524  29.360  31.118  1.00 92.86           C
ATOM    188  CG1 ILE A  78      -7.576  29.245  30.022  1.00 93.14           C
ATOM    189  CD1 ILE A  78      -8.797  30.112  30.221  1.00 90.50           C
ATOM    190  CG2 ILE A  78      -6.327  30.841  31.436  1.00 91.15           C
ATOM    191  C   ILE A  78      -4.222  28.476  31.837  1.00 94.80           C
ATOM    192  O   ILE A  78      -4.378  27.536  32.625  1.00100.34           O
ATOM    193  N   THR A  79      -3.226  29.350  31.988  1.00 87.39           N
ATOM    194  CA  THR A  79      -2.335  29.245  33.123  1.00 88.93           C
ATOM    195  CB  THR A  79      -1.177  30.211  33.029  1.00 91.51           C
ATOM    196  OG1 THR A  79      -1.702  31.517  32.821  1.00 95.59           O
ATOM    197  CG2 THR A  79      -0.209  29.830  31.889  1.00 88.18           C
ATOM    198  C   THR A  79      -3.121  29.624  34.336  1.00 90.39           C
ATOM    199  O   THR A  79      -4.221  30.104  34.202  1.00 90.57           O
ATOM    200  N   LYS A  80      -2.555  29.403  35.517  1.00 96.57           N
ATOM    201  CA  LYS A  80      -3.186  29.755  36.821  1.00103.56           C
ATOM    202  CB  LYS A  80      -2.258  29.272  37.965  1.00107.27           C
ATOM    203  CG  LYS A  80      -2.648  29.683  39.361  1.00111.02           C
ATOM    204  CD  LYS A  80      -1.573  29.286  40.425  1.00113.18           C
ATOM    205  CE  LYS A  80      -2.018  29.759  41.871  1.00114.97           C
ATOM    206  NZ  LYS A  80      -1.190  29.229  42.986  1.00115.55           N
ATOM    207  C   LYS A  80      -3.414  31.273  36.876  1.00 98.24           C
ATOM    208  O   LYS A  80      -4.525  31.773  36.929  1.00 94.50           O
ATOM    209  N   ASP A  81      -2.290  31.950  36.976  1.00 97.74           N
ATOM    210  CA  ASP A  81      -1.930  33.136  36.271  1.00 92.39           C
ATOM    211  CB  ASP A  81      -0.688  32.748  35.483  1.00 90.18           C
ATOM    212  CG  ASP A  81       0.246  33.861  35.356  1.00 91.78           C
ATOM    213  OD1 ASP A  81      -0.290  34.947  35.185  1.00 96.30           O
ATOM    214  OD2 ASP A  81       1.490  33.701  35.430  1.00 93.63           O
ATOM    215  C   ASP A  81      -2.944  33.801  35.335  1.00 97.11           C
ATOM    216  O   ASP A  81      -2.961  35.020  35.258  1.00103.49           O
ATOM    217  N   ASN A  82      -3.736  33.040  34.573  1.00 97.79           N
ATOM    218  CA  ASN A  82      -4.820  33.600  33.699  1.00 95.15           C
ATOM    219  CB  ASN A  82      -5.405  34.863  34.278  1.00 91.80           C
ATOM    220  CG  ASN A  82      -6.490  34.573  35.210  1.00 93.01           C
ATOM    221  OD1 ASN A  82      -7.168  33.560  35.072  1.00 93.33           O
ATOM    222  ND2 ASN A  82      -6.692  35.450  36.184  1.00 99.34           N
ATOM    223  C   ASN A  82      -4.616  33.807  32.201  1.00 97.06           C
ATOM    224  O   ASN A  82      -5.413  34.494  31.559  1.00 99.98           O
ATOM    225  N   VAL A  83      -3.585  33.192  31.646  1.00 95.06           N
ATOM    226  CA  VAL A  83      -3.208  33.414  30.270  1.00 94.66           C
ATOM    227  CB  VAL A  83      -1.696  33.640  30.201  1.00 93.90           C
ATOM    228  CG1 VAL A  83      -1.250  33.922  28.808  1.00 94.36           C
ATOM    229  CG2 VAL A  83      -1.306  34.757  31.107  1.00 95.59           C
ATOM    230  C   VAL A  83      -3.553  32.162  29.467  1.00 97.54           C
ATOM    231  O   VAL A  83      -3.137  31.067  29.828  1.00101.83           O
ATOM    232  N   PRO A  84      -4.316  32.302  28.374  1.00 96.65           N
ATOM    233  CA  PRO A  84      -4.556  31.157  27.506  1.00 92.64           C
ATOM    234  CB  PRO A  84      -5.491  31.746  26.465  1.00 91.16           C
ATOM    235  CG  PRO A  84      -5.065  33.146  26.406  1.00 92.31           C
ATOM    236  CD  PRO A  84      -4.974  33.496  27.840  1.00 94.74           C
ATOM    237  C   PRO A  84      -3.251  30.763  26.848  1.00 89.30           C
ATOM    238  O   PRO A  84      -2.399  31.627  26.640  1.00 89.94           O
ATOM    239  N   VAL A  85      -3.079  29.481  26.542  1.00 88.61           N
ATOM    240  CA  VAL A  85      -1.820  29.011  25.937  1.00 90.13           C
ATOM    241  CB  VAL A  85      -0.814  28.398  26.943  1.00 93.62           C
ATOM    242  CG1 VAL A  85       0.547  28.868  26.591  1.00 98.85           C
ATOM    243  CG2 VAL A  85      -1.091  28.735  28.364  1.00 96.19           C
ATOM    244  C   VAL A  85      -2.060  27.823  25.078  1.00 86.63           C
ATOM    245  O   VAL A  85      -2.985  27.074  25.349  1.00 86.98           O
ATOM    246  N   ARG A  86      -1.188  27.605  24.092  1.00 84.68           N
ATOM    247  CA  ARG A  86      -1.133  26.306  23.410  1.00 84.12           C
ATOM    248  CB  ARG A  86      -1.436  26.407  21.934  1.00 86.94           C
ATOM    249  CG  ARG A  86      -2.916  26.558  21.669  1.00 94.98           C
ATOM    250  CD  ARG A  86      -3.240  26.870  20.200  1.00102.67           C
ATOM    251  NE  ARG A  86      -4.444  27.689  20.121  1.00109.03           N
ATOM    252  CZ  ARG A  86      -5.344  27.625  19.147  1.00113.31           C
ATOM    253  NH1 ARG A  86      -5.177  26.779  18.148  1.00117.21           N
ATOM    254  NH2 ARG A  86      -6.420  28.410  19.175  1.00116.69           N
ATOM    255  C   ARG A  86       0.205  25.680  23.612  1.00 82.48           C
ATOM    256  O   ARG A  86       1.216  26.326  23.402  1.00 86.47           O
ATOM    257  N   VAL A  87       0.197  24.431  24.060  1.00 81.59           N
ATOM    258  CA  VAL A  87       1.397  23.736  24.476  1.00 81.23           C
ATOM    259  CB  VAL A  87       1.547  23.748  26.007  1.00 80.57           C
ATOM    260  CG1 VAL A  87       2.993  23.558  26.374  1.00 81.90           C
ATOM    261  CG2 VAL A  87       1.050  25.010  26.607  1.00 79.22           C
ATOM    262  C   VAL A  87       1.330  22.269  24.080  1.00 81.51           C
ATOM    263  O   VAL A  87       0.318  21.600  24.228  1.00 85.23           O
ATOM    264  N   ASN A  88       2.435  21.747  23.627  1.00 78.86           N
ATOM    265  CA  ASN A  88       2.490  20.368  23.253  1.00 79.82           C
ATOM    266  CB  ASN A  88       2.484  20.305  21.705  1.00 82.71           C
ATOM    267  CG  ASN A  88       3.728  20.944  21.083  1.00 82.15           C
ATOM    268  OD1 ASN A  88       4.392  21.750  21.707  1.00 90.69           O
ATOM    269  ND2 ASN A  88       4.050  20.569  19.885  1.00 79.68           N
ATOM    270  C   ASN A  88       3.776  19.804  23.881  1.00 79.58           C
ATOM    271  O   ASN A  88       4.496  20.519  24.524  1.00 83.18           O
ATOM    272  N   ALA A  89       4.106  18.542  23.716  1.00 79.34           N
ATOM    273  CA  ALA A  89       5.351  18.097  24.289  1.00 78.18           C
ATOM    274  CB  ALA A  89       5.246  18.078  25.742  1.00 82.61           C
ATOM    275  C   ALA A  89       5.597  16.727  23.830  1.00 79.60           C
ATOM    276  O   ALA A  89       4.840  16.208  23.006  1.00 84.74           O
ATOM    277  N   VAL A  90       6.609  16.104  24.420  1.00 73.94           N
ATOM    278  CA  VAL A  90       7.121  14.887  23.845  1.00 74.49           C
ATOM    279  CB  VAL A  90       8.385  15.200  22.959  1.00 71.31           C
ATOM    280  CG1 VAL A  90       9.319  14.046  22.808  1.00 70.58           C
ATOM    281  CG2 VAL A  90       7.932  15.626  21.649  1.00 69.96           C
ATOM    282  C   VAL A  90       7.345  13.958  24.996  1.00 76.80           C
ATOM    283  O   VAL A  90       7.934  14.365  26.011  1.00 78.27           O
ATOM    284  N   VAL A  91       6.847  12.732  24.851  1.00 75.86           N
ATOM    285  CA  VAL A  91       7.080  11.697  25.844  1.00 79.64           C
ATOM    286  CB  VAL A  91       5.779  10.979  26.108  1.00 79.22           C
ATOM    287  CG1 VAL A  91       6.017   9.754  27.020  1.00 78.78           C
ATOM    288  CG2 VAL A  91       4.782  11.949  26.703  1.00 78.98           C
ATOM    289  C   VAL A  91       8.150  10.679  25.409  1.00 82.22           C
ATOM    290  O   VAL A  91       8.044  10.117  24.316  1.00 88.21           O
ATOM    291  N   TYR A  92       9.166  10.437  26.236  1.00 81.45           N
ATOM    292  CA  TYR A  92      10.118   9.371  25.934  1.00 84.80           C
ATOM    293  CB  TYR A  92      11.553   9.840  26.028  1.00 87.95           C
ATOM    294  CG  TYR A  92      11.827  11.042  25.190  1.00 88.77           C
ATOM    295  CD1 TYR A  92      11.682  12.296  25.724  1.00 89.66           C
ATOM    296  CE1 TYR A  92      11.940  13.408  24.968  1.00 93.96           C
ATOM    297  CZ  TYR A  92      12.353  13.289  23.642  1.00 91.32           C
ATOM    298  OH  TYR A  92      12.589  14.455  22.973  1.00 91.30           O
ATOM    299  CE2 TYR A  92      12.499  12.054  23.059  1.00 87.81           C
ATOM    300  CD2 TYR A  92      12.238  10.926  23.849  1.00 89.90           C
ATOM    301  C   TYR A  92       9.936   8.175  26.830  1.00 87.82           C
ATOM    302  O   TYR A  92      10.112   8.278  28.044  1.00 87.52           O
ATOM    303  N   PHE A  93       9.606   7.043  26.204  1.00 88.19           N
ATOM    304  CA  PHE A  93       9.311   5.791  26.897  1.00 90.98           C
ATOM    305  CB  PHE A  93       7.814   5.632  26.995  1.00 85.65           C
ATOM    306  CG  PHE A  93       7.180   5.306  25.708  1.00 82.09           C
ATOM    307  CD1 PHE A  93       6.785   4.031  25.433  1.00 81.97           C
ATOM    308  CE1 PHE A  93       6.185   3.717  24.209  1.00 86.15           C
ATOM    309  CZ  PHE A  93       5.989   4.704  23.271  1.00 87.21           C
ATOM    310  CE2 PHE A  93       6.368   5.998  23.550  1.00 87.91           C
ATOM    311  CD2 PHE A  93       6.976   6.285  24.760  1.00 86.87           C
ATOM    312  C   PHE A  93       9.901   4.496  26.255  1.00 97.34           C
ATOM    313  O   PHE A  93      10.551   4.522  25.206  1.00101.04           O
ATOM    314  N   ARG A  94       9.591   3.361  26.874  1.00 96.50           N
ATOM    315  CA  ARG A  94      10.267   2.127  26.649  1.00 94.17           C
ATOM    316  CB  ARG A  94      11.581   2.236  27.415  1.00 97.56           C
ATOM    317  CG  ARG A  94      12.813   1.363  27.085  1.00106.23           C
ATOM    318  CD  ARG A  94      13.921   1.834  28.110  1.00108.98           C
ATOM    319  NE  ARG A  94      15.071   0.945  28.344  1.00118.89           N
ATOM    320  CZ  ARG A  94      16.237   1.021  27.673  1.00121.28           C
ATOM    321  NH1 ARG A  94      16.364   1.942  26.709  1.00122.23           N
ATOM    322  NH2 ARG A  94      17.269   0.184  27.939  1.00116.53           N
ATOM    323  C   ARG A  94       9.267   1.175  27.322  1.00 89.48           C
ATOM    324  O   ARG A  94       9.044   1.290  28.538  1.00 88.29           O
ATOM    325  N   VAL A  95       8.608   0.315  26.519  1.00 84.66           N
ATOM    326  CA  VAL A  95       7.798  -0.827  26.983  1.00 81.77           C
ATOM    327  CB  VAL A  95       7.141  -1.558  25.817  1.00 80.79           C
ATOM    328  CG1 VAL A  95       6.608  -2.919  26.233  1.00 83.33           C
ATOM    329  CG2 VAL A  95       6.024  -0.773  25.358  1.00 83.23           C
ATOM    330  C   VAL A  95       8.713  -1.814  27.681  1.00 84.97           C
ATOM    331  O   VAL A  95       9.616  -2.404  27.049  1.00 87.95           O
ATOM    332  N   VAL A  96       8.495  -1.981  28.981  1.00 81.92           N
ATOM    333  CA  VAL A  96       9.392  -2.764  29.816  1.00 83.14           C
ATOM    334  CB  VAL A  96       9.707  -2.050  31.150  1.00 80.15           C
ATOM    335  CG1 VAL A  96      10.638  -2.831  31.998  1.00 81.35           C
ATOM    336  CG2 VAL A  96      10.387  -0.748  30.890  1.00 85.85           C
ATOM    337  C   VAL A  96       8.812  -4.145  30.074  1.00 90.41           C
ATOM    338  O   VAL A  96       9.547  -5.066  30.449  1.00 95.99           O
ATOM    339  N   ASP A  97       7.503  -4.294  29.852  1.00 93.05           N
ATOM    340  CA  ASP A  97       6.787  -5.526  30.172  1.00 88.91           C
ATOM    341  CB  ASP A  97       6.360  -5.531  31.635  1.00 86.96           C
ATOM    342  CG  ASP A  97       5.409  -6.676  31.964  1.00 92.33           C
ATOM    343  OD1 ASP A  97       5.079  -7.456  31.024  1.00 91.24           O
ATOM    344  OD2 ASP A  97       4.998  -6.799  33.167  1.00 93.56           O
ATOM    345  C   ASP A  97       5.581  -5.611  29.263  1.00 87.45           C
ATOM    346  O   ASP A  97       4.519  -5.108  29.619  1.00 88.44           O
ATOM    347  N   PRO A  98       5.747  -6.263  28.097  1.00 84.93           N
ATOM    348  CA  PRO A  98       4.806  -6.274  26.976  1.00 83.59           C
ATOM    349  CB  PRO A  98       5.504  -7.136  25.930  1.00 79.60           C
ATOM    350  CG  PRO A  98       6.809  -7.372  26.402  1.00 80.44           C
ATOM    351  CD  PRO A  98       6.927  -7.095  27.834  1.00 80.03           C
ATOM    352  C   PRO A  98       3.479  -6.928  27.311  1.00 87.30           C
ATOM    353  O   PRO A  98       2.473  -6.611  26.700  1.00 92.25           O
ATOM    354  N   VAL A  99       3.489  -7.860  28.256  1.00 91.05           N
ATOM    355  CA  VAL A  99       2.297  -8.589  28.694  1.00 89.41           C
ATOM    356  CB  VAL A  99       2.676  -9.690  29.735  1.00 90.23           C
ATOM    357  CG1 VAL A  99       1.483 -10.494  30.169  1.00 89.85           C
ATOM    358  CG2 VAL A  99       3.785 -10.612  29.209  1.00 88.69           C
ATOM    359  C   VAL A  99       1.366  -7.559  29.335  1.00 88.87           C
ATOM    360  O   VAL A  99       0.200  -7.466  28.978  1.00 90.57           O
ATOM    361  N   LYS A 100       1.887  -6.755  30.256  1.00 86.75           N
ATOM    362  CA  LYS A 100       1.048  -5.699  30.865  1.00 88.48           C
ATOM    363  CB  LYS A 100       1.735  -5.025  32.068  1.00 81.94           C
ATOM    364  CG  LYS A 100       2.265  -6.039  33.083  1.00 81.19           C
ATOM    365  CD  LYS A 100       1.973  -5.701  34.512  1.00 83.17           C
ATOM    366  CE  LYS A 100       3.146  -4.967  35.142  1.00 89.16           C
ATOM    367  NZ  LYS A 100       3.165  -5.227  36.613  1.00 95.48           N
ATOM    368  C   LYS A 100       0.537  -4.674  29.831  1.00 90.66           C
ATOM    369  O   LYS A 100      -0.624  -4.287  29.855  1.00 94.31           O
ATOM    370  N   ALA A 101       1.406  -4.267  28.917  1.00 88.94           N
ATOM    371  CA  ALA A 101       1.072  -3.323  27.888  1.00 88.43           C
ATOM    372  CB  ALA A 101       2.308  -3.034  27.077  1.00 86.26           C
ATOM    373  C   ALA A 101      -0.040  -3.851  26.979  1.00 94.23           C
ATOM    374  O   ALA A 101      -0.825  -3.081  26.383  1.00 96.23           O
ATOM    375  N   VAL A 102      -0.101  -5.164  26.828  1.00 96.79           N
ATOM    376  CA  VAL A 102      -1.094  -5.712  25.917  1.00 98.19           C
ATOM    377  CB  VAL A 102      -0.593  -6.978  25.195  1.00 95.86           C
ATOM    378  CG1 VAL A 102      -1.679  -7.514  24.294  1.00 95.91           C
ATOM    379  CG2 VAL A 102       0.634  -6.640  24.367  1.00 90.81           C
ATOM    380  C   VAL A 102      -2.329  -5.988  26.742  1.00 98.88           C
ATOM    381  O   VAL A 102      -3.438  -5.687  26.351  1.00 99.68           O
ATOM    382  N   THR A 103      -2.095  -6.487  27.936  1.00 99.18           N
ATOM    383  CA  THR A 103      -3.131  -6.996  28.774  1.00 98.35           C
ATOM    384  CB  THR A 103      -2.494  -7.990  29.709  1.00 98.81           C
ATOM    385  OG1 THR A 103      -2.873  -9.291  29.255  1.00102.71           O
ATOM    386  CG2 THR A 103      -2.893  -7.773  31.133  1.00100.83           C
ATOM    387  C   THR A 103      -4.004  -5.969  29.489  1.00 99.86           C
ATOM    388  O   THR A 103      -5.188  -6.197  29.625  1.00103.73           O
ATOM    389  N   GLN A 104      -3.440  -4.822  29.868  1.00100.30           N
ATOM    390  CA  GLN A 104      -4.030  -3.923  30.860  1.00 95.68           C
ATOM    391  CB  GLN A 104      -2.957  -3.486  31.810  1.00 94.68           C
ATOM    392  CG  GLN A 104      -2.193  -4.623  32.413  1.00101.23           C
ATOM    393  CD  GLN A 104      -2.987  -5.408  33.454  1.00102.50           C
ATOM    394  OE1 GLN A 104      -3.980  -4.925  33.998  1.00103.29           O
ATOM    395  NE2 GLN A 104      -2.526  -6.617  33.749  1.00101.93           N
ATOM    396  C   GLN A 104      -4.707  -2.668  30.322  1.00 98.64           C
ATOM    397  O   GLN A 104      -5.394  -1.967  31.063  1.00103.45           O
ATOM    398  N   VAL A 105      -4.512  -2.362  29.054  1.00 96.68           N
ATOM    399  CA  VAL A 105      -5.145  -1.198  28.445  1.00101.99           C
ATOM    400  CB  VAL A 105      -4.205   0.072  28.479  1.00105.65           C
ATOM    401  CG1 VAL A 105      -2.727  -0.315  28.435  1.00105.68           C
ATOM    402  CG2 VAL A 105      -4.548   1.079  27.352  1.00107.38           C
ATOM    403  C   VAL A 105      -5.432  -1.699  27.043  1.00102.58           C
ATOM    404  O   VAL A 105      -4.895  -2.730  26.691  1.00106.20           O
ATOM    405  N   LYS A 106      -6.281  -1.049  26.249  1.00102.36           N
ATOM    406  CA  LYS A 106      -6.622  -1.647  24.969  1.00101.38           C
ATOM    407  CB  LYS A 106      -7.970  -1.173  24.445  1.00109.17           C
ATOM    408  CG  LYS A 106      -8.712  -2.222  23.577  1.00117.92           C
ATOM    409  CD  LYS A 106      -8.585  -1.852  22.024  1.00123.91           C
ATOM    410  CE  LYS A 106      -9.862  -2.431  21.305  1.00126.06           C
ATOM    411  NZ  LYS A 106     -10.138  -1.629  20.055  1.00127.47           N
ATOM    412  C   LYS A 106      -5.521  -1.316  24.010  1.00 98.83           C
ATOM    413  O   LYS A 106      -4.906  -2.208  23.443  1.00 95.81           O
ATOM    414  N   ASN A 107      -5.273  -0.024  23.842  1.00 96.13           N
ATOM    415  CA  ASN A 107      -4.122   0.445  23.124  1.00 91.74           C
ATOM    416  CB  ASN A 107      -4.546   1.114  21.846  1.00 87.96           C
ATOM    417  CG  ASN A 107      -3.375   1.724  21.079  1.00 98.50           C
ATOM    418  OD1 ASN A 107      -2.179   1.463  21.353  1.00105.10           O
ATOM    419  ND2 ASN A 107      -3.708   2.528  20.083  1.00 97.76           N
ATOM    420  C   ASN A 107      -3.301   1.405  24.000  1.00 96.53           C
ATOM    421  O   ASN A 107      -3.549   2.625  24.001  1.00 97.17           O
ATOM    422  N   TYR A 108      -2.333   0.835  24.747  1.00 98.65           N
ATOM    423  CA  TYR A 108      -1.272   1.574  25.478  1.00 95.59           C
ATOM    424  CB  TYR A 108      -0.143   0.625  25.928  1.00 95.25           C
ATOM    425  CG  TYR A 108       0.987   0.446  24.921  1.00 95.81           C
ATOM    426  CD1 TYR A 108       2.178   1.180  25.019  1.00 98.07           C
ATOM    427  CE1 TYR A 108       3.221   1.014  24.058  1.00 98.15           C
ATOM    428  CZ  TYR A 108       3.047   0.088  23.026  1.00 96.26           C
ATOM    429  OH  TYR A 108       3.998  -0.108  22.089  1.00 95.98           O
ATOM    430  CE2 TYR A 108       1.897  -0.650  22.921  1.00 95.66           C
ATOM    431  CD2 TYR A 108       0.863  -0.457  23.860  1.00 97.46           C
ATOM    432  C   TYR A 108      -0.672   2.802  24.748  1.00 96.65           C
ATOM    433  O   TYR A 108      -0.399   3.829  25.396  1.00 97.25           O
ATOM    434  N   ILE A 109      -0.450   2.727  23.431  1.00 94.97           N
ATOM    435  CA  ILE A 109      -0.029   3.944  22.748  1.00 95.16           C
ATOM    436  CB  ILE A 109       0.233   3.781  21.284  1.00 92.54           C
ATOM    437  CG1 ILE A 109       1.426   2.859  21.091  1.00 96.08           C
ATOM    438  CD1 ILE A 109       2.696   3.347  21.719  1.00 94.33           C
ATOM    439  CG2 ILE A 109       0.581   5.138  20.677  1.00 87.33           C
ATOM    440  C   ILE A 109      -1.032   5.057  22.946  1.00 98.21           C
ATOM    441  O   ILE A 109      -0.664   6.156  23.356  1.00102.53           O
ATOM    442  N   MET A 110      -2.299   4.784  22.686  1.00 99.09           N
ATOM    443  CA  MET A 110      -3.290   5.804  22.939  1.00103.45           C
ATOM    444  CB  MET A 110      -4.563   5.535  22.176  1.00110.15           C
ATOM    445  CG  MET A 110      -4.509   6.160  20.800  1.00113.71           C
ATOM    446  SD  MET A 110      -5.888   5.512  19.846  1.00117.25           S
ATOM    447  CE  MET A 110      -5.670   6.440  18.275  1.00116.29           C
ATOM    448  C   MET A 110      -3.540   6.077  24.416  1.00 96.27           C
ATOM    449  O   MET A 110      -3.597   7.231  24.823  1.00 97.69           O
ATOM    450  N   ALA A 111      -3.635   5.050  25.235  1.00 90.51           N
ATOM    451  CA  ALA A 111      -3.689   5.316  26.674  1.00 91.51           C
ATOM    452  CB  ALA A 111      -3.666   4.020  27.496  1.00 91.56           C
ATOM    453  C   ALA A 111      -2.616   6.314  27.160  1.00 90.11           C
ATOM    454  O   ALA A 111      -2.961   7.302  27.783  1.00 93.32           O
ATOM    455  N   THR A 112      -1.337   6.074  26.865  1.00 88.35           N
ATOM    456  CA  THR A 112      -0.247   7.023  27.193  1.00 85.91           C
ATOM    457  CB  THR A 112       1.063   6.468  26.700  1.00 83.93           C
ATOM    458  OG1 THR A 112       1.236   5.195  27.299  1.00 87.09           O
ATOM    459  CG2 THR A 112       2.180   7.316  27.134  1.00 82.51           C
ATOM    460  C   THR A 112      -0.465   8.441  26.603  1.00 84.83           C
ATOM    461  O   THR A 112      -0.323   9.485  27.277  1.00 76.18           O
ATOM    462  N   SER A 113      -0.835   8.461  25.334  1.00 86.14           N
ATOM    463  CA  SER A 113      -1.270   9.679  24.742  1.00 87.15           C
ATOM    464  CB  SER A 113      -1.751   9.460  23.336  1.00 86.41           C
ATOM    465  OG  SER A 113      -1.685  10.710  22.701  1.00 91.98           O
ATOM    466  C   SER A 113      -2.316  10.373  25.613  1.00 89.08           C
ATOM    467  O   SER A 113      -2.129  11.536  25.931  1.00 92.23           O
ATOM    468  N   GLN A 114      -3.361   9.675  26.065  1.00 89.62           N
ATOM    469  CA  GLN A 114      -4.328  10.298  27.006  1.00 92.66           C
ATOM    470  CB  GLN A 114      -5.499   9.366  27.375  1.00100.10           C
ATOM    471  CG  GLN A 114      -6.678   9.293  26.358  1.00113.40           C
ATOM    472  CD  GLN A 114      -7.243  10.675  25.926  1.00119.84           C
ATOM    473  OE1 GLN A 114      -7.251  11.638  26.715  1.00120.15           O
ATOM    474  NE2 GLN A 114      -7.712  10.768  24.654  1.00121.22           N
ATOM    475  C   GLN A 114      -3.714  10.912  28.285  1.00 90.31           C
ATOM    476  O   GLN A 114      -3.662  12.135  28.412  1.00 88.70           O
ATOM    477  N   ILE A 115      -3.246  10.088  29.222  1.00 88.50           N
ATOM    478  CA  ILE A 115      -2.760  10.628  30.493  1.00 92.34           C
ATOM    479  CB  ILE A 115      -1.978   9.621  31.359  1.00 92.80           C
ATOM    480  CG1 ILE A 115      -1.660   8.411  30.539  1.00 98.74           C
ATOM    481  CD1 ILE A 115      -0.326   7.820  30.937  1.00109.82           C
ATOM    482  CG2 ILE A 115      -2.745   9.182  32.581  1.00 88.83           C
ATOM    483  C   ILE A 115      -1.829  11.782  30.204  1.00 92.67           C
ATOM    484  O   ILE A 115      -1.804  12.778  30.951  1.00 91.77           O
ATOM    485  N   SER A 116      -1.067  11.660  29.115  1.00 91.43           N
ATOM    486  CA  SER A 116      -0.147  12.734  28.752  1.00 88.04           C
ATOM    487  CB  SER A 116       0.698  12.381  27.543  1.00 85.28           C
ATOM    488  OG  SER A 116       1.712  11.504  28.009  1.00 87.06           O
ATOM    489  C   SER A 116      -0.845  14.078  28.623  1.00 84.48           C
ATOM    490  O   SER A 116      -0.440  15.038  29.328  1.00 76.33           O
ATOM    491  N   GLN A 117      -1.903  14.123  27.797  1.00 80.51           N
ATOM    492  CA  GLN A 117      -2.739  15.313  27.706  1.00 87.22           C
ATOM    493  CB  GLN A 117      -3.824  15.170  26.671  1.00 93.29           C
ATOM    494  CG  GLN A 117      -3.457  14.166  25.609  1.00104.07           C
ATOM    495  CD  GLN A 117      -4.150  14.404  24.265  1.00106.95           C
ATOM    496  OE1 GLN A 117      -4.449  15.566  23.907  1.00109.64           O
ATOM    497  NE2 GLN A 117      -4.373  13.306  23.496  1.00101.87           N
ATOM    498  C   GLN A 117      -3.365  15.710  29.036  1.00 90.10           C
ATOM    499  O   GLN A 117      -3.168  16.850  29.473  1.00 92.37           O
ATOM    500  N   THR A 118      -4.084  14.793  29.698  1.00 90.28           N
ATOM    501  CA  THR A 118      -4.704  15.117  30.995  1.00 88.97           C
ATOM    502  CB  THR A 118      -5.348  13.898  31.699  1.00 90.53           C
ATOM    503  OG1 THR A 118      -6.455  13.433  30.922  1.00 91.06           O
ATOM    504  CG2 THR A 118      -5.863  14.268  33.130  1.00 90.95           C
ATOM    505  C   THR A 118      -3.709  15.805  31.918  1.00 88.43           C
ATOM    506  O   THR A 118      -3.986  16.870  32.449  1.00 93.65           O
ATOM    507  N   THR A 119      -2.539  15.214  32.086  1.00 87.77           N
ATOM    508  CA  THR A 119      -1.504  15.814  32.936  1.00 86.55           C
ATOM    509  CB  THR A 119      -0.278  14.904  33.021  1.00 84.34           C
ATOM    510  OG1 THR A 119      -0.718  13.566  33.208  1.00 80.30           O
ATOM    511  CG2 THR A 119       0.649  15.334  34.158  1.00 81.42           C
ATOM    512  C   THR A 119      -1.033  17.187  32.441  1.00 85.59           C
ATOM    513  O   THR A 119      -0.997  18.128  33.213  1.00 83.75           O
ATOM    514  N   LEU A 120      -0.646  17.278  31.164  1.00 85.04           N
ATOM    515  CA  LEU A 120      -0.131  18.509  30.625  1.00 79.49           C
ATOM    516  CB  LEU A 120       0.272  18.332  29.170  1.00 73.96           C
ATOM    517  CG  LEU A 120       0.764  19.627  28.534  1.00 71.34           C
ATOM    518  CD1 LEU A 120       1.980  20.159  29.234  1.00 72.24           C
ATOM    519  CD2 LEU A 120       1.060  19.469  27.071  1.00 71.45           C
ATOM    520  C   LEU A 120      -1.188  19.595  30.836  1.00 82.68           C
ATOM    521  O   LEU A 120      -0.854  20.700  31.258  1.00 79.86           O
ATOM    522  N   ARG A 121      -2.459  19.262  30.594  1.00 86.92           N
ATOM    523  CA  ARG A 121      -3.561  20.180  30.893  1.00 92.38           C
ATOM    524  CB  ARG A 121      -4.921  19.557  30.551  1.00 93.33           C
ATOM    525  CG  ARG A 121      -6.156  20.400  30.965  1.00 99.84           C
ATOM    526  CD  ARG A 121      -7.324  20.479  29.894  1.00101.94           C
ATOM    527  NE  ARG A 121      -6.888  20.325  28.501  1.00111.06           N
ATOM    528  CZ  ARG A 121      -6.941  19.174  27.793  1.00119.94           C
ATOM    529  NH1 ARG A 121      -7.433  18.011  28.310  1.00119.06           N
ATOM    530  NH2 ARG A 121      -6.497  19.176  26.530  1.00123.28           N
ATOM    531  C   ARG A 121      -3.537  20.552  32.367  1.00 88.89           C
ATOM    532  O   ARG A 121      -3.403  21.708  32.744  1.00 90.00           O
ATOM    533  N   SER A 122      -3.652  19.547  33.204  1.00 86.94           N
ATOM    534  CA  SER A 122      -3.759  19.772  34.629  1.00 84.91           C
ATOM    535  CB  SER A 122      -3.758  18.431  35.347  1.00 79.93           C
ATOM    536  OG  SER A 122      -3.906  18.701  36.706  1.00 83.93           O
ATOM    537  C   SER A 122      -2.652  20.692  35.173  1.00 81.62           C
ATOM    538  O   SER A 122      -2.907  21.690  35.835  1.00 86.07           O
ATOM    539  N   VAL A 123      -1.438  20.333  34.833  1.00 76.92           N
ATOM    540  CA  VAL A 123      -0.231  20.970  35.256  1.00 72.12           C
ATOM    541  CB  VAL A 123       1.000  20.232  34.599  1.00 68.31           C
ATOM    542  CG1 VAL A 123       2.192  21.074  34.544  1.00 61.65           C
ATOM    543  CG2 VAL A 123       1.315  18.954  35.334  1.00 67.45           C
ATOM    544  C   VAL A 123      -0.264  22.430  34.862  1.00 73.99           C
ATOM    545  O   VAL A 123      -0.008  23.321  35.677  1.00 76.78           O
ATOM    546  N   ILE A 124      -0.585  22.700  33.615  1.00 73.70           N
ATOM    547  CA  ILE A 124      -0.570  24.077  33.198  1.00 71.94           C
ATOM    548  CB  ILE A 124      -0.847  24.187  31.745  1.00 68.61           C
ATOM    549  CG1 ILE A 124       0.368  23.755  30.970  1.00 66.57           C
ATOM    550  CD1 ILE A 124      -0.060  23.159  29.684  1.00 70.76           C
ATOM    551  CG2 ILE A 124      -1.191  25.562  31.383  1.00 69.08           C
ATOM    552  C   ILE A 124      -1.586  24.829  34.026  1.00 75.75           C
ATOM    553  O   ILE A 124      -1.289  25.905  34.505  1.00 78.38           O
ATOM    554  N   GLY A 125      -2.753  24.219  34.246  1.00 82.06           N
ATOM    555  CA  GLY A 125      -3.790  24.724  35.177  1.00 85.49           C
ATOM    556  C   GLY A 125      -3.256  25.311  36.473  1.00 88.49           C
ATOM    557  O   GLY A 125      -3.491  26.477  36.754  1.00 88.67           O
ATOM    558  N   GLN A 126      -2.513  24.512  37.239  1.00 89.83           N
ATOM    559  CA  GLN A 126      -1.864  24.976  38.456  1.00 93.15           C
ATOM    560  CB  GLN A 126      -1.677  23.813  39.434  1.00 99.79           C
ATOM    561  CG  GLN A 126      -2.954  23.107  39.841  1.00107.80           C
ATOM    562  CD  GLN A 126      -2.754  21.596  39.931  1.00113.49           C
ATOM    563  OE1 GLN A 126      -2.035  21.116  40.793  1.00116.71           O
ATOM    564  NE2 GLN A 126      -3.374  20.845  39.021  1.00118.68           N
ATOM    565  C   GLN A 126      -0.500  25.588  38.227  1.00 90.62           C
ATOM    566  O   GLN A 126       0.387  25.398  39.051  1.00 94.10           O
ATOM    567  N   ALA A 127      -0.307  26.313  37.130  1.00 89.33           N
ATOM    568  CA  ALA A 127       1.025  26.902  36.826  1.00 86.67           C
ATOM    569  CB  ALA A 127       1.772  26.057  35.855  1.00 81.27           C
ATOM    570  C   ALA A 127       0.981  28.342  36.329  1.00 87.17           C
ATOM    571  O   ALA A 127       0.074  28.777  35.602  1.00 86.29           O
ATOM    572  N   HIS A 128       1.971  29.099  36.737  1.00 87.07           N
ATOM    573  CA  HIS A 128       1.982  30.492  36.377  1.00 89.35           C
ATOM    574  CB  HIS A 128       2.768  31.332  37.423  1.00 99.00           C
ATOM    575  CG  HIS A 128       1.975  31.680  38.646  1.00102.49           C
ATOM    576  ND1 HIS A 128       0.991  32.648  38.646  1.00104.53           N
ATOM    577  CE1 HIS A 128       0.435  32.724  39.840  1.00102.78           C
ATOM    578  NE2 HIS A 128       1.035  31.845  40.621  1.00109.44           N
ATOM    579  CD2 HIS A 128       2.002  31.176  39.899  1.00106.00           C
ATOM    580  C   HIS A 128       2.607  30.597  35.002  1.00 86.76           C
ATOM    581  O   HIS A 128       3.596  29.907  34.694  1.00 75.97           O
ATOM    582  N   LEU A 129       2.047  31.466  34.160  1.00 90.40           N
ATOM    583  CA  LEU A 129       2.702  31.713  32.860  1.00 89.78           C
ATOM    584  CB  LEU A 129       2.276  33.034  32.188  1.00 85.44           C
ATOM    585  CG  LEU A 129       3.038  33.346  30.903  1.00 79.89           C
ATOM    586  CD1 LEU A 129       2.988  32.153  29.973  1.00 80.89           C
ATOM    587  CD2 LEU A 129       2.440  34.543  30.250  1.00 79.47           C
ATOM    588  C   LEU A 129       4.222  31.597  33.023  1.00 86.12           C
ATOM    589  O   LEU A 129       4.886  30.906  32.269  1.00 85.29           O
ATOM    590  N   ASP A 130       4.768  32.208  34.046  1.00 86.76           N
ATOM    591  CA  ASP A 130       6.180  32.160  34.088  1.00 93.73           C
ATOM    592  CB  ASP A 130       6.746  33.155  35.058  1.00105.42           C
ATOM    593  CG  ASP A 130       8.063  33.697  34.554  1.00115.64           C
ATOM    594  OD1 ASP A 130       8.076  34.297  33.415  1.00116.98           O
ATOM    595  OD2 ASP A 130       9.083  33.447  35.260  1.00119.82           O
ATOM    596  C   ASP A 130       6.840  30.798  34.252  1.00 92.54           C
ATOM    597  O   ASP A 130       8.016  30.640  33.920  1.00 89.18           O
ATOM    598  N   GLU A 131       6.104  29.804  34.733  1.00 92.93           N
ATOM    599  CA  GLU A 131       6.727  28.509  34.953  1.00 92.93           C
ATOM    600  CB  GLU A 131       5.974  27.665  35.951  1.00 93.56           C
ATOM    601  CG  GLU A 131       5.801  28.304  37.331  1.00 97.40           C
ATOM    602  CD  GLU A 131       4.779  27.554  38.202  1.00 99.88           C
ATOM    603  OE1 GLU A 131       4.943  26.309  38.413  1.00102.66           O
ATOM    604  OE2 GLU A 131       3.819  28.223  38.666  1.00103.74           O
ATOM    605  C   GLU A 131       6.862  27.779  33.645  1.00 93.57           C
ATOM    606  O   GLU A 131       7.820  27.013  33.483  1.00100.61           O
ATOM    607  N   LEU A 132       5.948  28.034  32.702  1.00 87.58           N
ATOM    608  CA  LEU A 132       6.083  27.468  31.363  1.00 83.61           C
ATOM    609  CB  LEU A 132       4.832  27.627  30.517  1.00 84.43           C
ATOM    610  CG  LEU A 132       3.508  27.201  31.119  1.00 87.90           C
ATOM    611  CD1 LEU A 132       2.482  27.116  30.043  1.00 89.36           C
ATOM    612  CD2 LEU A 132       3.666  25.867  31.816  1.00 90.83           C
ATOM    613  C   LEU A 132       7.217  28.082  30.605  1.00 84.65           C
ATOM    614  O   LEU A 132       7.846  27.411  29.806  1.00 90.93           O
ATOM    615  N   LEU A 133       7.482  29.363  30.806  1.00 84.35           N
ATOM    616  CA  LEU A 133       8.535  29.994  30.013  1.00 85.50           C
ATOM    617  CB  LEU A 133       8.203  31.454  29.701  1.00 81.76           C
ATOM    618  CG  LEU A 133       6.746  31.708  29.279  1.00 79.07           C
ATOM    619  CD1 LEU A 133       6.351  33.226  29.119  1.00 74.25           C
ATOM    620  CD2 LEU A 133       6.460  30.885  28.038  1.00 75.20           C
ATOM    621  C   LEU A 133       9.908  29.881  30.669  1.00 91.67           C
ATOM    622  O   LEU A 133      10.916  30.076  29.984  1.00 97.73           O
ATOM    623  N   SER A 134       9.964  29.540  31.966  1.00 94.31           N
ATOM    624  CA  SER A 134      11.208  29.705  32.721  1.00 95.80           C
ATOM    625  CB  SER A 134      11.180  31.013  33.473  1.00 96.64           C
ATOM    626  OG  SER A 134      11.237  32.088  32.557  1.00 98.53           O
ATOM    627  C   SER A 134      11.660  28.627  33.662  1.00100.80           C
ATOM    628  O   SER A 134      12.776  28.668  34.156  1.00 97.65           O
ATOM    629  N   GLU A 135      10.820  27.652  33.925  1.00112.31           N
ATOM    630  CA  GLU A 135      11.256  26.550  34.766  1.00120.70           C
ATOM    631  CB  GLU A 135      10.558  26.617  36.137  1.00124.92           C
ATOM    632  CG  GLU A 135      11.212  27.554  37.216  1.00127.42           C
ATOM    633  CD  GLU A 135      10.251  27.882  38.410  1.00125.88           C
ATOM    634  OE1 GLU A 135       9.276  28.638  38.225  1.00125.15           O
ATOM    635  OE2 GLU A 135      10.474  27.396  39.543  1.00128.11           O
ATOM    636  C   GLU A 135      10.863  25.299  34.034  1.00120.40           C
ATOM    637  O   GLU A 135       9.930  24.592  34.462  1.00120.53           O
ATOM    638  N   ARG A 136      11.520  25.053  32.899  1.00119.52           N
ATOM    639  CA  ARG A 136      11.136  23.887  32.086  1.00119.33           C
ATOM    640  CB  ARG A 136      11.881  23.770  30.751  1.00115.70           C
ATOM    641  CG  ARG A 136      11.453  24.714  29.716  1.00111.34           C
ATOM    642  CD  ARG A 136       9.976  24.826  29.580  1.00104.57           C
ATOM    643  NE  ARG A 136       9.803  25.439  28.298  1.00100.39           N
ATOM    644  CZ  ARG A 136       9.909  24.749  27.192  1.00101.84           C
ATOM    645  NH1 ARG A 136      10.120  23.444  27.283  1.00106.55           N
ATOM    646  NH2 ARG A 136       9.782  25.346  26.023  1.00102.98           N
ATOM    647  C   ARG A 136      11.576  22.729  32.865  1.00118.14           C
ATOM    648  O   ARG A 136      10.810  21.832  33.174  1.00116.17           O
ATOM    649  N   ASP A 137      12.856  22.787  33.178  1.00119.47           N
ATOM    650  CA  ASP A 137      13.520  21.701  33.782  1.00122.67           C
ATOM    651  CB  ASP A 137      14.815  22.208  34.368  1.00132.59           C
ATOM    652  CG  ASP A 137      15.907  21.194  34.250  1.00141.41           C
ATOM    653  OD1 ASP A 137      15.706  20.192  33.511  1.00145.11           O
ATOM    654  OD2 ASP A 137      16.959  21.388  34.895  1.00147.39           O
ATOM    655  C   ASP A 137      12.637  21.094  34.862  1.00119.24           C
ATOM    656  O   ASP A 137      12.457  19.874  34.940  1.00119.27           O
ATOM    657  N   LYS A 138      12.057  21.969  35.672  1.00114.32           N
ATOM    658  CA  LYS A 138      11.219  21.543  36.771  1.00107.84           C
ATOM    659  CB  LYS A 138      11.138  22.662  37.850  1.00110.56           C
ATOM    660  CG  LYS A 138      12.496  22.893  38.684  1.00109.88           C
ATOM    661  CD  LYS A 138      12.603  24.317  39.278  1.00110.10           C
ATOM    662  CE  LYS A 138      13.997  24.971  39.107  1.00113.54           C
ATOM    663  NZ  LYS A 138      14.734  25.158  40.412  1.00111.84           N
ATOM    664  C   LYS A 138       9.869  21.039  36.230  1.00 99.88           C
ATOM    665  O   LYS A 138       9.361  20.003  36.677  1.00 97.60           O
ATOM    666  N   LEU A 139       9.329  21.721  35.220  1.00 92.49           N
ATOM    667  CA  LEU A 139       8.085  21.260  34.575  1.00 89.11           C
ATOM    668  CB  LEU A 139       7.671  22.179  33.457  1.00 81.97           C
ATOM    669  CG  LEU A 139       6.533  23.058  33.893  1.00 82.82           C
ATOM    670  CD1 LEU A 139       5.648  22.923  32.791  1.00 83.35           C
ATOM    671  CD2 LEU A 139       5.798  22.673  35.197  1.00 83.07           C
ATOM    672  C   LEU A 139       8.151  19.864  34.002  1.00 88.28           C
ATOM    673  O   LEU A 139       7.325  19.013  34.266  1.00 85.81           O
ATOM    674  N   ASN A 140       9.149  19.642  33.177  1.00 90.11           N
ATOM    675  CA  ASN A 140       9.256  18.378  32.545  1.00 87.63           C
ATOM    676  CB  ASN A 140      10.448  18.315  31.587  1.00 86.58           C
ATOM    677  CG  ASN A 140      10.524  19.476  30.638  1.00 82.45           C
ATOM    678  OD1 ASN A 140       9.529  19.972  30.071  1.00 79.62           O
ATOM    679  ND2 ASN A 140      11.747  19.898  30.424  1.00 88.73           N
ATOM    680  C   ASN A 140       9.421  17.336  33.620  1.00 88.24           C
ATOM    681  O   ASN A 140       8.847  16.249  33.497  1.00 93.21           O
ATOM    682  N   MET A 141      10.190  17.662  34.670  1.00 84.65           N
ATOM    683  CA  MET A 141      10.474  16.695  35.732  1.00 83.29           C
ATOM    684  CB  MET A 141      11.500  17.258  36.645  1.00 79.10           C
ATOM    685  CG  MET A 141      11.861  16.424  37.782  1.00 82.50           C
ATOM    686  SD  MET A 141      12.794  17.590  38.848  1.00 92.47           S
ATOM    687  CE  MET A 141      14.435  16.844  38.663  1.00 92.01           C
ATOM    688  C   MET A 141       9.169  16.359  36.444  1.00 83.47           C
ATOM    689  O   MET A 141       8.772  15.198  36.487  1.00 80.46           O
ATOM    690  N   GLN A 142       8.460  17.390  36.903  1.00 84.99           N
ATOM    691  CA  GLN A 142       7.068  17.247  37.297  1.00 87.88           C
ATOM    692  CB  GLN A 142       6.418  18.622  37.472  1.00 88.16           C
ATOM    693  CG  GLN A 142       7.127  19.577  38.423  1.00 89.98           C
ATOM    694  CD  GLN A 142       6.455  20.931  38.448  1.00 92.10           C
ATOM    695  OE1 GLN A 142       5.228  21.027  38.401  1.00 96.73           O
ATOM    696  NE2 GLN A 142       7.252  21.993  38.495  1.00 95.46           N
ATOM    697  C   GLN A 142       6.249  16.391  36.288  1.00 90.18           C
ATOM    698  O   GLN A 142       5.475  15.523  36.697  1.00 96.49           O
ATOM    699  N   LEU A 143       6.417  16.618  34.982  1.00 87.34           N
ATOM    700  CA  LEU A 143       5.691  15.851  33.986  1.00 83.47           C
ATOM    701  CB  LEU A 143       5.807  16.498  32.618  1.00 81.65           C
ATOM    702  CG  LEU A 143       4.900  17.718  32.397  1.00 83.08           C
ATOM    703  CD1 LEU A 143       5.194  18.328  31.032  1.00 84.27           C
ATOM    704  CD2 LEU A 143       3.398  17.452  32.564  1.00 76.97           C
ATOM    705  C   LEU A 143       6.136  14.389  33.929  1.00 85.51           C
ATOM    706  O   LEU A 143       5.299  13.487  33.764  1.00 90.85           O
ATOM    707  N   GLN A 144       7.427  14.129  34.101  1.00 80.32           N
ATOM    708  CA  GLN A 144       7.882  12.748  34.015  1.00 81.51           C
ATOM    709  CB  GLN A 144       9.403  12.635  33.909  1.00 81.91           C
ATOM    710  CG  GLN A 144       9.919  11.244  33.615  1.00 77.67           C
ATOM    711  CD  GLN A 144      10.160  10.541  34.895  1.00 85.33           C
ATOM    712  OE1 GLN A 144       9.974  11.132  35.968  1.00 88.86           O
ATOM    713  NE2 GLN A 144      10.580   9.280  34.830  1.00 86.87           N
ATOM    714  C   GLN A 144       7.345  11.980  35.190  1.00 83.88           C
ATOM    715  O   GLN A 144       6.767  10.918  35.023  1.00 86.09           O
ATOM    716  N   ARG A 145       7.519  12.553  36.373  1.00 88.23           N
ATOM    717  CA  ARG A 145       7.001  12.021  37.645  1.00 89.90           C
ATOM    718  CB  ARG A 145       7.116  13.096  38.732  1.00 93.67           C
ATOM    719  CG  ARG A 145       6.530  12.742  40.072  1.00 97.51           C
ATOM    720  CD  ARG A 145       7.316  11.643  40.721  1.00101.70           C
ATOM    721  NE  ARG A 145       6.642  11.077  41.881  1.00102.50           N
ATOM    722  CZ  ARG A 145       6.738   9.803  42.225  1.00104.32           C
ATOM    723  NH1 ARG A 145       7.475   8.963  41.501  1.00107.32           N
ATOM    724  NH2 ARG A 145       6.102   9.365  43.290  1.00103.53           N
ATOM    725  C   ARG A 145       5.553  11.560  37.576  1.00 88.83           C
ATOM    726  O   ARG A 145       5.264  10.396  37.896  1.00 91.84           O
ATOM    727  N   ILE A 146       4.649  12.451  37.173  1.00 81.29           N
ATOM    728  CA  ILE A 146       3.241  12.086  37.220  1.00 81.21           C
ATOM    729  CB  ILE A 146       2.284  13.266  36.965  1.00 77.57           C
ATOM    730  CG1 ILE A 146       2.499  14.333  38.032  1.00 72.39           C
ATOM    731  CD1 ILE A 146       2.503  15.693  37.556  1.00 74.07           C
ATOM    732  CG2 ILE A 146       0.812  12.749  36.935  1.00 71.62           C
ATOM    733  C   ILE A 146       2.955  11.057  36.181  1.00 82.89           C
ATOM    734  O   ILE A 146       2.188  10.109  36.427  1.00 81.30           O
ATOM    735  N   ILE A 147       3.548  11.289  35.010  1.00 82.79           N
ATOM    736  CA  ILE A 147       3.215  10.498  33.845  1.00 85.03           C
ATOM    737  CB  ILE A 147       3.554  11.221  32.535  1.00 83.42           C
ATOM    738  CG1 ILE A 147       2.538  12.340  32.278  1.00 83.84           C
ATOM    739  CD1 ILE A 147       2.777  13.175  30.990  1.00 82.43           C
ATOM    740  CG2 ILE A 147       3.586  10.229  31.364  1.00 81.43           C
ATOM    741  C   ILE A 147       3.843   9.095  33.900  1.00 88.77           C
ATOM    742  O   ILE A 147       3.250   8.132  33.376  1.00 86.10           O
ATOM    743  N   ASP A 148       5.022   8.965  34.525  1.00 89.15           N
ATOM    744  CA  ASP A 148       5.652   7.647  34.559  1.00 90.01           C
ATOM    745  CB  ASP A 148       7.123   7.633  34.993  1.00 87.28           C
ATOM    746  CG  ASP A 148       7.723   6.214  34.967  1.00 90.55           C
ATOM    747  OD1 ASP A 148       7.030   5.241  34.509  1.00 89.74           O
ATOM    748  OD2 ASP A 148       8.893   6.082  35.409  1.00 90.81           O
ATOM    749  C   ASP A 148       4.841   6.792  35.482  1.00 91.06           C
ATOM    750  O   ASP A 148       4.603   5.623  35.172  1.00 91.12           O
ATOM    751  N   GLU A 149       4.437   7.401  36.597  1.00 88.58           N
ATOM    752  CA  GLU A 149       3.705   6.741  37.638  1.00 92.96           C
ATOM    753  CB  GLU A 149       3.343   7.758  38.707  1.00104.69           C
ATOM    754  CG  GLU A 149       2.157   7.376  39.645  1.00107.65           C
ATOM    755  CD  GLU A 149       2.661   6.569  40.812  1.00112.43           C
ATOM    756  OE1 GLU A 149       3.392   7.143  41.660  1.00112.58           O
ATOM    757  OE2 GLU A 149       2.360   5.356  40.859  1.00115.91           O
ATOM    758  C   GLU A 149       2.413   6.212  37.097  1.00 91.05           C
ATOM    759  O   GLU A 149       2.087   5.065  37.306  1.00 94.80           O
ATOM    760  N   ALA A 150       1.659   7.073  36.428  1.00 88.68           N
ATOM    761  CA  ALA A 150       0.345   6.717  35.939  1.00 86.70           C
ATOM    762  CB  ALA A 150      -0.213   7.843  35.099  1.00 86.98           C
ATOM    763  C   ALA A 150       0.478   5.492  35.090  1.00 86.40           C
ATOM    764  O   ALA A 150      -0.396   4.686  34.978  1.00 92.25           O
ATOM    765  N   THR A 151       1.638   5.347  34.517  1.00 89.46           N
ATOM    766  CA  THR A 151       1.810   4.556  33.347  1.00 87.04           C
ATOM    767  CB  THR A 151       2.880   5.290  32.509  1.00 81.28           C
ATOM    768  OG1 THR A 151       2.344   5.671  31.227  1.00 70.31           O
ATOM    769  CG2 THR A 151       4.278   4.553  32.526  1.00 75.11           C
ATOM    770  C   THR A 151       2.213   3.110  33.668  1.00 91.23           C
ATOM    771  O   THR A 151       2.241   2.293  32.789  1.00 99.75           O
ATOM    772  N   ASP A 152       2.497   2.768  34.910  1.00 91.39           N
ATOM    773  CA  ASP A 152       3.176   1.517  35.143  1.00 94.31           C
ATOM    774  CB  ASP A 152       4.015   1.598  36.398  1.00 97.04           C
ATOM    775  CG  ASP A 152       4.881   2.828  36.429  1.00103.22           C
ATOM    776  OD1 ASP A 152       5.252   3.375  35.322  1.00104.96           O
ATOM    777  OD2 ASP A 152       5.172   3.234  37.578  1.00102.19           O
ATOM    778  C   ASP A 152       2.256   0.319  35.195  1.00 98.50           C
ATOM    779  O   ASP A 152       2.664  -0.790  34.816  1.00 98.82           O
ATOM    780  N   PRO A 153       1.021   0.508  35.692  1.00101.76           N
ATOM    781  CA  PRO A 153       0.030  -0.560  35.502  1.00103.71           C
ATOM    782  CB  PRO A 153      -1.313   0.174  35.579  1.00103.43           C
ATOM    783  CG  PRO A 153      -1.023   1.484  36.293  1.00104.54           C
ATOM    784  CD  PRO A 153       0.476   1.634  36.468  1.00102.23           C
ATOM    785  C   PRO A 153       0.150  -1.218  34.129  1.00102.33           C
ATOM    786  O   PRO A 153      -0.139  -2.405  34.029  1.00106.30           O
ATOM    787  N   TRP A 154       0.593  -0.454  33.114  1.00 98.17           N
ATOM    788  CA  TRP A 154       0.690  -0.905  31.700  1.00 96.38           C
ATOM    789  CB  TRP A 154       0.223   0.166  30.695  1.00 99.85           C
ATOM    790  CG  TRP A 154      -0.943   0.959  31.155  1.00101.48           C
ATOM    791  CD1 TRP A 154      -1.925   0.556  32.001  1.00100.84           C
ATOM    792  NE1 TRP A 154      -2.825   1.561  32.189  1.00101.12           N
ATOM    793  CE2 TRP A 154      -2.441   2.651  31.459  1.00102.19           C
ATOM    794  CD2 TRP A 154      -1.252   2.307  30.794  1.00103.49           C
ATOM    795  CE3 TRP A 154      -0.639   3.261  29.963  1.00105.24           C
ATOM    796  CZ3 TRP A 154      -1.246   4.529  29.827  1.00102.81           C
ATOM    797  CH2 TRP A 154      -2.433   4.836  30.511  1.00101.82           C
ATOM    798  CZ2 TRP A 154      -3.036   3.916  31.335  1.00103.01           C
ATOM    799  C   TRP A 154       2.056  -1.396  31.260  1.00 91.54           C
ATOM    800  O   TRP A 154       2.216  -1.838  30.131  1.00 86.21           O
ATOM    801  N   GLY A 155       3.035  -1.309  32.146  1.00 91.86           N
ATOM    802  CA  GLY A 155       4.335  -1.942  31.912  1.00 92.63           C
ATOM    803  C   GLY A 155       5.256  -1.065  31.103  1.00 91.67           C
ATOM    804  O   GLY A 155       6.192  -1.560  30.487  1.00 94.39           O
ATOM    805  N   ILE A 156       4.962   0.234  31.102  1.00 88.21           N
ATOM    806  CA  ILE A 156       5.744   1.254  30.432  1.00 85.45           C
ATOM    807  CB  ILE A 156       4.802   2.302  29.870  1.00 85.62           C
ATOM    808  CG1 ILE A 156       4.000   1.803  28.666  1.00 88.27           C
ATOM    809  CD1 ILE A 156       4.003   0.328  28.478  1.00 89.37           C
ATOM    810  CG2 ILE A 156       5.588   3.483  29.434  1.00 87.32           C
ATOM    811  C   ILE A 156       6.617   2.014  31.428  1.00 86.57           C
ATOM    812  O   ILE A 156       6.073   2.564  32.427  1.00 88.41           O
ATOM    813  N   LYS A 157       7.936   2.075  31.180  1.00 86.91           N
ATOM    814  CA  LYS A 157       8.759   3.072  31.894  1.00 91.44           C
ATOM    815  CB  LYS A 157      10.190   2.638  32.248  1.00 93.17           C
ATOM    816  CG  LYS A 157      10.982   3.825  32.940  1.00 97.76           C
ATOM    817  CD  LYS A 157      12.067   3.372  33.944  1.00103.54           C
ATOM    818  CE  LYS A 157      13.400   2.868  33.233  1.00111.57           C
ATOM    819  NZ  LYS A 157      14.463   2.213  34.125  1.00106.82           N
ATOM    820  C   LYS A 157       8.843   4.365  31.121  1.00 87.68           C
ATOM    821  O   LYS A 157       9.355   4.359  30.010  1.00 87.58           O
ATOM    822  N   VAL A 158       8.345   5.462  31.701  1.00 83.63           N
ATOM    823  CA  VAL A 158       8.511   6.758  31.061  1.00 84.03           C
ATOM    824  CB  VAL A 158       7.287   7.720  31.184  1.00 82.51           C
ATOM    825  CG1 VAL A 158       7.564   9.064  30.505  1.00 75.75           C
ATOM    826  CG2 VAL A 158       6.044   7.088  30.574  1.00 80.55           C
ATOM    827  C   VAL A 158       9.782   7.351  31.620  1.00 87.25           C
ATOM    828  O   VAL A 158       9.966   7.449  32.816  1.00 91.27           O
ATOM    829  N   THR A 159      10.642   7.732  30.688  1.00 90.98           N
ATOM    830  CA  THR A 159      12.018   8.149  30.861  1.00 85.66           C
ATOM    831  CB  THR A 159      12.726   7.701  29.618  1.00 85.79           C
ATOM    832  OG1 THR A 159      13.203   6.390  29.882  1.00 86.73           O
ATOM    833  CG2 THR A 159      13.840   8.651  29.145  1.00 88.59           C
ATOM    834  C   THR A 159      12.094   9.652  31.025  1.00 87.55           C
ATOM    835  O   THR A 159      12.679  10.116  31.979  1.00 91.62           O
ATOM    836  N   ALA A 160      11.498  10.419  30.117  1.00 81.28           N
ATOM    837  CA  ALA A 160      11.467  11.835  30.301  1.00 77.38           C
ATOM    838  CB  ALA A 160      12.623  12.419  29.651  1.00 79.60           C
ATOM    839  C   ALA A 160      10.233  12.317  29.629  1.00 82.43           C
ATOM    840  O   ALA A 160       9.667  11.582  28.822  1.00 88.46           O
ATOM    841  N   VAL A 161       9.808  13.543  29.943  1.00 81.48           N
ATOM    842  CA  VAL A 161       8.741  14.175  29.199  1.00 80.20           C
ATOM    843  CB  VAL A 161       7.413  14.041  29.946  1.00 82.44           C
ATOM    844  CG1 VAL A 161       6.245  14.896  29.268  1.00 82.47           C
ATOM    845  CG2 VAL A 161       7.051  12.572  30.130  1.00 81.31           C
ATOM    846  C   VAL A 161       9.059  15.652  29.064  1.00 85.33           C
ATOM    847  O   VAL A 161       8.743  16.402  29.952  1.00 92.96           O
ATOM    848  N   GLU A 162       9.655  16.093  27.961  1.00 87.06           N
ATOM    849  CA  GLU A 162       9.921  17.526  27.760  1.00 85.15           C
ATOM    850  CB  GLU A 162      11.186  17.702  26.981  1.00 83.34           C
ATOM    851  CG  GLU A 162      12.213  16.733  27.384  1.00 87.94           C
ATOM    852  CD  GLU A 162      13.375  16.729  26.434  1.00 91.86           C
ATOM    853  OE1 GLU A 162      13.165  17.067  25.220  1.00 91.03           O
ATOM    854  OE2 GLU A 162      14.485  16.383  26.931  1.00 92.40           O
ATOM    855  C   GLU A 162       8.823  18.242  26.990  1.00 87.08           C
ATOM    856  O   GLU A 162       8.451  17.795  25.901  1.00 87.62           O
ATOM    857  N   ILE A 163       8.314  19.342  27.558  1.00 86.58           N
ATOM    858  CA  ILE A 163       7.433  20.266  26.833  1.00 85.10           C
ATOM    859  CB  ILE A 163       7.139  21.521  27.674  1.00 84.21           C
ATOM    860  CG1 ILE A 163       5.926  21.263  28.535  1.00 85.27           C
ATOM    861  CD1 ILE A 163       5.792  22.287  29.555  1.00 88.79           C
ATOM    862  CG2 ILE A 163       6.841  22.744  26.819  1.00 78.37           C
ATOM    863  C   ILE A 163       8.116  20.656  25.544  1.00 86.41           C
ATOM    864  O   ILE A 163       9.279  20.967  25.572  1.00 85.46           O
ATOM    865  N   LYS A 164       7.413  20.608  24.417  1.00 92.67           N
ATOM    866  CA  LYS A 164       7.983  21.089  23.152  1.00 97.94           C
ATOM    867  CB  LYS A 164       7.528  20.231  21.955  1.00105.83           C
ATOM    868  CG  LYS A 164       8.511  20.303  20.759  1.00113.36           C
ATOM    869  CD  LYS A 164       7.822  20.197  19.396  1.00116.59           C
ATOM    870  CE  LYS A 164       7.753  18.728  18.906  1.00119.66           C
ATOM    871  NZ  LYS A 164       7.021  18.658  17.579  1.00121.38           N
ATOM    872  C   LYS A 164       7.813  22.633  22.914  1.00 94.15           C
ATOM    873  O   LYS A 164       8.691  23.393  23.296  1.00 98.24           O
ATOM    874  N   ASP A 165       6.730  23.086  22.286  1.00 86.60           N
ATOM    875  CA  ASP A 165       6.531  24.502  22.036  1.00 86.14           C
ATOM    876  CB  ASP A 165       6.004  24.787  20.643  1.00 92.44           C
ATOM    877  CG  ASP A 165       6.947  24.411  19.557  1.00 99.08           C
ATOM    878  OD1 ASP A 165       8.050  25.023  19.472  1.00104.03           O
ATOM    879  OD2 ASP A 165       6.543  23.525  18.763  1.00100.59           O
ATOM    880  C   ASP A 165       5.430  24.991  22.901  1.00 88.61           C
ATOM    881  O   ASP A 165       4.378  24.332  23.057  1.00 86.05           O
ATOM    882  N   VAL A 166       5.635  26.210  23.383  1.00 89.74           N
ATOM    883  CA  VAL A 166       4.604  26.951  24.071  1.00 86.25           C
ATOM    884  CB  VAL A 166       5.141  27.457  25.378  1.00 84.01           C
ATOM    885  CG1 VAL A 166       4.195  28.480  26.008  1.00 85.12           C
ATOM    886  CG2 VAL A 166       5.400  26.287  26.305  1.00 84.79           C
ATOM    887  C   VAL A 166       4.279  28.112  23.176  1.00 87.85           C
ATOM    888  O   VAL A 166       5.206  28.694  22.608  1.00 93.67           O
ATOM    889  N   GLU A 167       2.986  28.415  23.037  1.00 85.20           N
ATOM    890  CA  GLU A 167       2.506  29.502  22.228  1.00 90.60           C
ATOM    891  CB  GLU A 167       1.723  28.970  21.036  1.00 94.62           C
ATOM    892  CG  GLU A 167       2.505  28.059  20.079  1.00102.98           C
ATOM    893  CD  GLU A 167       1.711  27.580  18.816  1.00104.38           C
ATOM    894  OE1 GLU A 167       0.443  27.500  18.807  1.00106.52           O
ATOM    895  OE2 GLU A 167       2.406  27.265  17.816  1.00109.43           O
ATOM    896  C   GLU A 167       1.564  30.360  23.031  1.00 92.31           C
ATOM    897  O   GLU A 167       0.684  29.848  23.758  1.00 94.75           O
ATOM    898  N   LEU A 168       1.696  31.674  22.846  1.00 93.04           N
ATOM    899  CA  LEU A 168       0.908  32.696  23.593  1.00 91.49           C
ATOM    900  CB  LEU A 168       1.841  33.608  24.432  1.00 94.76           C
ATOM    901  CG  LEU A 168       3.000  33.007  25.243  1.00 94.17           C
ATOM    902  CD1 LEU A 168       4.063  34.008  25.402  1.00 94.24           C
ATOM    903  CD2 LEU A 168       2.544  32.553  26.599  1.00 96.13           C
ATOM    904  C   LEU A 168       0.189  33.613  22.654  1.00 85.22           C
ATOM    905  O   LEU A 168       0.624  33.756  21.514  1.00 80.41           O
ATOM    906  N   PRO A 169      -0.873  34.299  23.139  1.00 86.00           N
ATOM    907  CA  PRO A 169      -1.530  35.364  22.350  1.00 85.02           C
ATOM    908  CB  PRO A 169      -2.352  36.090  23.381  1.00 80.60           C
ATOM    909  CG  PRO A 169      -2.746  35.011  24.371  1.00 82.71           C
ATOM    910  CD  PRO A 169      -1.550  34.089  24.438  1.00 86.45           C
ATOM    911  C   PRO A 169      -0.538  36.297  21.642  1.00 91.51           C
ATOM    912  O   PRO A 169       0.537  36.635  22.168  1.00 97.76           O
ATOM    913  N   ALA A 170      -0.857  36.658  20.413  1.00 94.00           N
ATOM    914  CA  ALA A 170       0.121  37.344  19.596  1.00 93.46           C
ATOM    915  CB  ALA A 170      -0.220  37.220  18.140  1.00 90.82           C
ATOM    916  C   ALA A 170       0.207  38.800  20.024  1.00 96.20           C
ATOM    917  O   ALA A 170      -0.805  39.429  20.336  1.00 92.97           O
ATOM    918  N   GLY A 171       1.433  39.318  20.030  1.00100.68           N
ATOM    919  CA  GLY A 171       1.726  40.623  20.592  1.00100.95           C
ATOM    920  C   GLY A 171       2.163  40.445  22.038  1.00102.57           C
ATOM    921  O   GLY A 171       3.096  41.112  22.476  1.00106.12           O
ATOM    922  N   MET A 172       1.510  39.534  22.769  1.00 96.73           N
ATOM    923  CA  MET A 172       1.765  39.357  24.189  1.00 94.31           C
ATOM    924  CB  MET A 172       1.106  38.089  24.731  1.00 97.31           C
ATOM    925  CG  MET A 172      -0.013  38.271  25.778  1.00 95.14           C
ATOM    926  SD  MET A 172       0.333  37.149  27.150  1.00 94.31           S
ATOM    927  CE  MET A 172      -1.086  37.447  28.215  1.00 92.67           C
ATOM    928  C   MET A 172       3.238  39.344  24.554  1.00 94.41           C
ATOM    929  O   MET A 172       3.679  40.208  25.298  1.00 96.23           O
ATOM    930  N   GLN A 173       4.010  38.392  24.042  1.00 94.23           N
ATOM    931  CA  GLN A 173       5.432  38.351  24.388  1.00 96.91           C
ATOM    932  CB  GLN A 173       6.058  37.066  23.870  1.00 94.52           C
ATOM    933  CG  GLN A 173       7.278  36.582  24.653  1.00 96.47           C
ATOM    934  CD  GLN A 173       8.162  35.550  23.876  1.00100.81           C
ATOM    935  OE1 GLN A 173       8.014  35.329  22.628  1.00102.88           O
ATOM    936  NE2 GLN A 173       9.101  34.929  24.616  1.00 94.98           N
ATOM    937  C   GLN A 173       6.265  39.633  23.989  1.00101.57           C
ATOM    938  O   GLN A 173       7.298  39.928  24.607  1.00100.34           O
ATOM    939  N   LYS A 174       5.826  40.403  22.987  1.00105.29           N
ATOM    940  CA  LYS A 174       6.461  41.715  22.713  1.00111.89           C
ATOM    941  CB  LYS A 174       5.908  42.389  21.446  1.00115.70           C
ATOM    942  CG  LYS A 174       6.585  41.945  20.141  1.00122.85           C
ATOM    943  CD  LYS A 174       5.637  42.063  18.892  1.00124.51           C
ATOM    944  CE  LYS A 174       5.572  40.733  18.084  1.00128.68           C
ATOM    945  NZ  LYS A 174       5.713  40.936  16.619  1.00129.30           N
ATOM    946  C   LYS A 174       6.269  42.647  23.902  1.00106.54           C
ATOM    947  O   LYS A 174       7.226  43.254  24.387  1.00104.92           O
ATOM    948  N   ALA A 175       5.018  42.753  24.356  1.00101.91           N
ATOM    949  CA  ALA A 175       4.686  43.556  25.514  1.00 96.33           C
ATOM    950  CB  ALA A 175       3.212  43.504  25.812  1.00 92.63           C
ATOM    951  C   ALA A 175       5.497  43.002  26.663  1.00 94.90           C
ATOM    952  O   ALA A 175       6.266  43.734  27.286  1.00 92.55           O
ATOM    953  N   MET A 176       5.389  41.696  26.898  1.00 94.01           N
ATOM    954  CA  MET A 176       6.061  41.093  28.047  1.00 94.45           C
ATOM    955  CB  MET A 176       5.776  39.611  28.143  1.00 92.15           C
ATOM    956  CG  MET A 176       4.435  39.249  28.652  1.00 92.83           C
ATOM    957  SD  MET A 176       4.488  37.511  29.178  1.00 96.93           S
ATOM    958  CE  MET A 176       5.665  36.784  28.062  1.00 93.82           C
ATOM    959  C   MET A 176       7.560  41.309  27.979  1.00 93.07           C
ATOM    960  O   MET A 176       8.227  41.346  28.990  1.00 87.96           O
ATOM    961  N   ALA A 177       8.078  41.455  26.769  1.00 99.18           N
ATOM    962  CA  ALA A 177       9.500  41.714  26.580  1.00103.83           C
ATOM    963  CB  ALA A 177       9.901  41.445  25.144  1.00106.75           C
ATOM    964  C   ALA A 177       9.837  43.138  26.949  1.00105.23           C
ATOM    965  O   ALA A 177      10.707  43.354  27.792  1.00104.68           O
ATOM    966  N   ARG A 178       9.141  44.095  26.322  1.00107.21           N
ATOM    967  CA  ARG A 178       9.312  45.503  26.630  1.00109.01           C
ATOM    968  CB  ARG A 178       8.326  46.373  25.857  1.00113.45           C
ATOM    969  CG  ARG A 178       8.777  46.577  24.413  1.00123.07           C
ATOM    970  CD  ARG A 178       8.336  47.925  23.821  1.00132.02           C
ATOM    971  NE  ARG A 178       7.511  47.738  22.606  1.00139.73           N
ATOM    972  CZ  ARG A 178       6.167  47.664  22.587  1.00141.92           C
ATOM    973  NH1 ARG A 178       5.459  47.780  23.724  1.00142.40           N
ATOM    974  NH2 ARG A 178       5.529  47.482  21.425  1.00140.68           N
ATOM    975  C   ARG A 178       9.253  45.751  28.134  1.00108.25           C
ATOM    976  O   ARG A 178      10.242  46.177  28.719  1.00108.51           O
ATOM    977  N   GLN A 179       8.131  45.395  28.758  1.00106.78           N
ATOM    978  CA  GLN A 179       7.870  45.638  30.182  1.00104.45           C
ATOM    979  CB  GLN A 179       6.470  45.183  30.532  1.00107.19           C
ATOM    980  CG  GLN A 179       6.026  45.486  31.975  1.00114.62           C
ATOM    981  CD  GLN A 179       4.851  44.580  32.434  1.00116.10           C
ATOM    982  OE1 GLN A 179       4.140  43.987  31.609  1.00117.29           O
ATOM    983  NE2 GLN A 179       4.654  44.480  33.752  1.00121.13           N
ATOM    984  C   GLN A 179       8.790  44.991  31.175  1.00100.58           C
ATOM    985  O   GLN A 179       8.672  45.262  32.333  1.00102.29           O
ATOM    986  N   ALA A 180       9.668  44.103  30.747  1.00102.93           N
ATOM    987  CA  ALA A 180      10.485  43.333  31.662  1.00100.21           C
ATOM    988  CB  ALA A 180      10.609  41.946  31.195  1.00 98.28           C
ATOM    989  C   ALA A 180      11.796  43.989  31.553  1.00104.70           C
ATOM    990  O   ALA A 180      12.561  44.000  32.505  1.00107.72           O
ATOM    991  N   GLU A 181      12.066  44.502  30.350  1.00110.55           N
ATOM    992  CA  GLU A 181      13.246  45.330  30.051  1.00112.74           C
ATOM    993  CB  GLU A 181      13.228  45.763  28.580  1.00110.85           C
ATOM    994  CG  GLU A 181      14.557  46.122  27.962  1.00113.89           C
ATOM    995  CD  GLU A 181      14.492  46.185  26.400  1.00116.62           C
ATOM    996  OE1 GLU A 181      13.533  46.812  25.841  1.00114.83           O
ATOM    997  OE2 GLU A 181      15.411  45.605  25.736  1.00116.73           O
ATOM    998  C   GLU A 181      13.151  46.548  30.972  1.00111.67           C
ATOM    999  O   GLU A 181      14.165  47.006  31.501  1.00114.83           O
ATOM   1000  N   ALA A 182      11.915  47.016  31.196  1.00104.51           N
ATOM   1001  CA  ALA A 182      11.643  48.219  31.961  1.00 98.91           C
ATOM   1002  CB  ALA A 182      10.285  48.804  31.598  1.00 96.44           C
ATOM   1003  C   ALA A 182      11.722  47.962  33.442  1.00 98.58           C
ATOM   1004  O   ALA A 182      12.109  48.818  34.213  1.00102.09           O
ATOM   1005  N   GLU A 183      11.357  46.779  33.862  1.00100.14           N
ATOM   1006  CA  GLU A 183      11.383  46.513  35.274  1.00102.84           C
ATOM   1007  CB  GLU A 183      10.160  45.656  35.666  1.00103.80           C
ATOM   1008  CG  GLU A 183      10.345  44.591  36.694  1.00110.58           C
ATOM   1009  CD  GLU A 183      10.239  45.124  38.103  1.00118.26           C
ATOM   1010  OE1 GLU A 183       9.609  46.214  38.273  1.00117.25           O
ATOM   1011  OE2 GLU A 183      10.801  44.450  39.033  1.00122.81           O
ATOM   1012  C   GLU A 183      12.784  45.984  35.657  1.00104.98           C
ATOM   1013  O   GLU A 183      13.193  46.084  36.805  1.00 99.79           O
ATOM   1014  N   ARG A 184      13.551  45.493  34.681  1.00115.87           N
ATOM   1015  CA  ARG A 184      14.937  45.067  34.948  1.00120.69           C
ATOM   1016  CB  ARG A 184      15.598  44.409  33.727  1.00126.22           C
ATOM   1017  CG  ARG A 184      17.080  43.970  33.914  1.00125.07           C
ATOM   1018  CD  ARG A 184      17.900  44.208  32.619  1.00132.10           C
ATOM   1019  NE  ARG A 184      19.270  43.649  32.647  1.00136.29           N
ATOM   1020  CZ  ARG A 184      20.237  43.924  31.749  1.00140.79           C
ATOM   1021  NH1 ARG A 184      20.024  44.771  30.732  1.00142.14           N
ATOM   1022  NH2 ARG A 184      21.435  43.352  31.864  1.00140.11           N
ATOM   1023  C   ARG A 184      15.740  46.281  35.370  1.00123.74           C
ATOM   1024  O   ARG A 184      16.607  46.161  36.232  1.00125.23           O
ATOM   1025  N   GLU A 185      15.438  47.437  34.757  1.00125.76           N
ATOM   1026  CA  GLU A 185      16.129  48.719  35.018  1.00126.52           C
ATOM   1027  CB  GLU A 185      15.891  49.714  33.882  1.00126.65           C
ATOM   1028  CG  GLU A 185      16.448  49.290  32.531  1.00132.24           C
ATOM   1029  CD  GLU A 185      16.360  50.398  31.475  1.00134.72           C
ATOM   1030  OE1 GLU A 185      16.396  51.594  31.870  1.00138.25           O
ATOM   1031  OE2 GLU A 185      16.260  50.073  30.256  1.00137.60           O
ATOM   1032  C   GLU A 185      15.645  49.340  36.316  1.00123.11           C
ATOM   1033  O   GLU A 185      16.429  49.620  37.228  1.00121.37           O
ATOM   1034  N   ARG A 186      14.335  49.548  36.387  1.00121.06           N
ATOM   1035  CA  ARG A 186      13.707  50.077  37.564  1.00119.47           C
ATOM   1036  CB  ARG A 186      12.198  50.038  37.390  1.00120.95           C
ATOM   1037  CG  ARG A 186      11.424  50.535  38.574  1.00125.95           C
ATOM   1038  CD  ARG A 186      10.382  49.518  39.085  1.00130.28           C
ATOM   1039  NE  ARG A 186       9.647  50.118  40.191  1.00137.65           N
ATOM   1040  CZ  ARG A 186       8.754  51.103  40.035  1.00142.67           C
ATOM   1041  NH1 ARG A 186       8.469  51.551  38.813  1.00144.42           N
ATOM   1042  NH2 ARG A 186       8.128  51.640  41.086  1.00145.02           N
ATOM   1043  C   ARG A 186      14.172  49.295  38.801  1.00119.29           C
ATOM   1044  O   ARG A 186      14.154  49.808  39.907  1.00121.01           O
ATOM   1045  N   ARG A 187      14.618  48.061  38.615  1.00121.91           N
ATOM   1046  CA  ARG A 187      15.131  47.268  39.742  1.00125.06           C
ATOM   1047  CB  ARG A 187      15.077  45.757  39.435  1.00130.14           C
ATOM   1048  CG  ARG A 187      15.148  44.847  40.642  1.00135.62           C
ATOM   1049  CD  ARG A 187      15.210  43.406  40.193  1.00141.89           C
ATOM   1050  NE  ARG A 187      16.448  42.759  40.661  1.00148.51           N
ATOM   1051  CZ  ARG A 187      16.994  41.665  40.112  1.00151.30           C
ATOM   1052  NH1 ARG A 187      16.416  41.076  39.067  1.00152.10           N
ATOM   1053  NH2 ARG A 187      18.125  41.148  40.600  1.00152.17           N
ATOM   1054  C   ARG A 187      16.547  47.736  40.064  1.00120.86           C
ATOM   1055  O   ARG A 187      16.843  48.088  41.206  1.00120.25           O
ATOM   1056  N   ALA A 188      17.392  47.760  39.033  1.00116.16           N
ATOM   1057  CA  ALA A 188      18.762  48.260  39.105  1.00113.49           C
ATOM   1058  CB  ALA A 188      19.350  48.379  37.721  1.00113.16           C
ATOM   1059  C   ALA A 188      18.849  49.593  39.822  1.00113.53           C
ATOM   1060  O   ALA A 188      19.634  49.729  40.766  1.00114.47           O
ATOM   1061  N   ARG A 189      18.042  50.558  39.375  1.00111.43           N
ATOM   1062  CA  ARG A 189      17.849  51.820  40.084  1.00111.12           C
ATOM   1063  CB  ARG A 189      16.646  52.538  39.509  1.00115.34           C
ATOM   1064  CG  ARG A 189      16.801  54.053  39.321  1.00122.11           C
ATOM   1065  CD  ARG A 189      15.788  54.525  38.262  1.00127.51           C
ATOM   1066  NE  ARG A 189      16.166  53.951  36.972  1.00135.98           N
ATOM   1067  CZ  ARG A 189      15.514  54.111  35.816  1.00139.61           C
ATOM   1068  NH1 ARG A 189      14.402  54.846  35.744  1.00140.28           N
ATOM   1069  NH2 ARG A 189      15.996  53.521  34.719  1.00141.27           N
ATOM   1070  C   ARG A 189      17.642  51.558  41.580  1.00109.97           C
ATOM   1071  O   ARG A 189      18.601  51.564  42.351  1.00109.66           O
ATOM   1072  N   ILE A 190      16.409  51.286  41.987  1.00108.98           N
ATOM   1073  CA  ILE A 190      16.120  51.098  43.398  1.00114.14           C
ATOM   1074  CB  ILE A 190      14.711  50.483  43.669  1.00117.25           C
ATOM   1075  CG1 ILE A 190      14.692  48.958  43.413  1.00126.21           C
ATOM   1076  CD1 ILE A 190      13.710  48.060  44.366  1.00126.86           C
ATOM   1077  CG2 ILE A 190      13.670  51.135  42.782  1.00117.54           C
ATOM   1078  C   ILE A 190      17.232  50.329  44.124  1.00109.80           C
ATOM   1079  O   ILE A 190      17.760  50.822  45.111  1.00110.33           O
ATOM   1080  N   THR A 191      17.622  49.153  43.639  1.00106.32           N
ATOM   1081  CA  THR A 191      18.560  48.331  44.422  1.00107.62           C
ATOM   1082  CB  THR A 191      19.057  46.990  43.734  1.00109.79           C
ATOM   1083  OG1 THR A 191      18.121  46.486  42.769  1.00107.17           O
ATOM   1084  CG2 THR A 191      19.422  45.934  44.814  1.00107.41           C
ATOM   1085  C   THR A 191      19.837  49.103  44.731  1.00104.76           C
ATOM   1086  O   THR A 191      20.363  49.000  45.855  1.00104.06           O
ATOM   1087  N   LEU A 192      20.351  49.798  43.701  1.00 97.86           N
ATOM   1088  CA  LEU A 192      21.566  50.622  43.804  1.00 92.67           C
ATOM   1089  CB  LEU A 192      22.022  51.103  42.433  1.00 92.75           C
ATOM   1090  CG  LEU A 192      23.128  52.161  42.388  1.00 85.07           C
ATOM   1091  CD1 LEU A 192      24.458  51.479  42.634  1.00 80.01           C
ATOM   1092  CD2 LEU A 192      23.088  52.897  41.028  1.00 84.90           C
ATOM   1093  C   LEU A 192      21.383  51.853  44.682  1.00 90.51           C
ATOM   1094  O   LEU A 192      22.111  51.998  45.673  1.00 84.46           O
ATOM   1095  N   ALA A 193      20.431  52.731  44.301  1.00 85.02           N
ATOM   1096  CA  ALA A 193      20.019  53.826  45.160  1.00 82.93           C
ATOM   1097  CB  ALA A 193      18.733  54.385  44.720  1.00 73.28           C
ATOM   1098  C   ALA A 193      19.963  53.347  46.627  1.00 89.96           C
ATOM   1099  O   ALA A 193      20.341  54.097  47.543  1.00 95.31           O
ATOM   1100  N   GLU A 194      19.566  52.087  46.842  1.00 91.75           N
ATOM   1101  CA  GLU A 194      19.520  51.518  48.183  1.00 93.11           C
ATOM   1102  CB  GLU A 194      18.730  50.210  48.241  1.00 99.55           C
ATOM   1103  CG  GLU A 194      17.614  50.124  49.333  1.00104.18           C
ATOM   1104  CD  GLU A 194      17.736  51.151  50.463  1.00107.66           C
ATOM   1105  OE1 GLU A 194      17.332  52.332  50.250  1.00108.69           O
ATOM   1106  OE2 GLU A 194      18.210  50.766  51.570  1.00108.66           O
ATOM   1107  C   GLU A 194      20.898  51.296  48.743  1.00 91.53           C
ATOM   1108  O   GLU A 194      21.198  51.845  49.783  1.00 97.34           O
ATOM   1109  N   ALA A 195      21.737  50.512  48.063  1.00 90.47           N
ATOM   1110  CA  ALA A 195      23.131  50.215  48.511  1.00 89.07           C
ATOM   1111  CB  ALA A 195      23.916  49.611  47.384  1.00 86.76           C
ATOM   1112  C   ALA A 195      23.880  51.442  48.996  1.00 91.48           C
ATOM   1113  O   ALA A 195      24.548  51.425  50.040  1.00 91.59           O
ATOM   1114  N   GLU A 196      23.756  52.494  48.186  1.00 93.93           N
ATOM   1115  CA  GLU A 196      24.294  53.803  48.431  1.00 91.79           C
ATOM   1116  CB  GLU A 196      24.108  54.680  47.205  1.00 90.77           C
ATOM   1117  CG  GLU A 196      25.135  54.325  46.158  1.00 90.87           C
ATOM   1118  CD  GLU A 196      25.052  55.131  44.867  1.00 94.57           C
ATOM   1119  OE1 GLU A 196      24.123  56.005  44.639  1.00 87.36           O
ATOM   1120  OE2 GLU A 196      25.971  54.819  44.062  1.00 97.02           O
ATOM   1121  C   GLU A 196      23.704  54.443  49.655  1.00 95.38           C
ATOM   1122  O   GLU A 196      24.473  54.843  50.529  1.00 98.82           O
ATOM   1123  N   ARG A 197      22.373  54.538  49.753  1.00 97.73           N
ATOM   1124  CA  ARG A 197      21.790  55.134  50.958  1.00102.12           C
ATOM   1125  CB  ARG A 197      20.296  55.021  51.024  1.00111.80           C
ATOM   1126  CG  ARG A 197      19.616  56.208  50.463  1.00126.05           C
ATOM   1127  CD  ARG A 197      18.226  55.777  50.081  1.00136.70           C
ATOM   1128  NE  ARG A 197      17.474  56.782  49.334  1.00143.99           N
ATOM   1129  CZ  ARG A 197      16.429  56.482  48.565  1.00147.64           C
ATOM   1130  NH1 ARG A 197      16.042  55.208  48.437  1.00148.55           N
ATOM   1131  NH2 ARG A 197      15.776  57.444  47.917  1.00148.97           N
ATOM   1132  C   ARG A 197      22.344  54.472  52.166  1.00 99.29           C
ATOM   1133  O   ARG A 197      22.541  55.118  53.182  1.00 98.90           O
ATOM   1134  N   GLN A 198      22.624  53.186  52.062  1.00 96.77           N
ATOM   1135  CA  GLN A 198      23.126  52.514  53.228  1.00103.02           C
ATOM   1136  CB  GLN A 198      22.811  51.037  53.198  1.00107.98           C
ATOM   1137  CG  GLN A 198      21.382  50.694  53.574  1.00116.42           C
ATOM   1138  CD  GLN A 198      21.016  49.323  53.045  1.00122.45           C
ATOM   1139  OE1 GLN A 198      21.325  48.300  53.676  1.00123.31           O
ATOM   1140  NE2 GLN A 198      20.391  49.284  51.851  1.00124.26           N
ATOM   1141  C   GLN A 198      24.603  52.763  53.448  1.00101.01           C
ATOM   1142  O   GLN A 198      25.032  52.975  54.585  1.00101.21           O
ATOM   1143  N   ALA A 199      25.374  52.758  52.364  1.00100.60           N
ATOM   1144  CA  ALA A 199      26.809  53.072  52.439  1.00 97.63           C
ATOM   1145  CB  ALA A 199      27.460  53.015  51.037  1.00 95.24           C
ATOM   1146  C   ALA A 199      27.003  54.446  53.101  1.00 94.90           C
ATOM   1147  O   ALA A 199      27.816  54.582  54.044  1.00 88.23           O
ATOM   1148  N   ALA A 200      26.212  55.423  52.610  1.00 93.51           N
ATOM   1149  CA  ALA A 200      26.148  56.788  53.137  1.00 92.15           C
ATOM   1150  CB  ALA A 200      25.102  57.571  52.453  1.00 87.14           C
ATOM   1151  C   ALA A 200      25.883  56.775  54.623  1.00 94.55           C
ATOM   1152  O   ALA A 200      26.541  57.480  55.367  1.00 98.78           O
ATOM   1153  N   GLU A 201      24.958  55.941  55.068  1.00 94.42           N
ATOM   1154  CA  GLU A 201      24.705  55.835  56.488  1.00 94.60           C
ATOM   1155  CB  GLU A 201      23.467  54.989  56.725  1.00102.67           C
ATOM   1156  CG  GLU A 201      22.802  55.258  58.062  1.00112.97           C
ATOM   1157  CD  GLU A 201      21.443  54.613  58.141  1.00116.80           C
ATOM   1158  OE1 GLU A 201      21.094  53.944  57.144  1.00117.75           O
ATOM   1159  OE2 GLU A 201      20.741  54.770  59.177  1.00118.96           O
ATOM   1160  C   GLU A 201      25.897  55.276  57.272  1.00 90.42           C
ATOM   1161  O   GLU A 201      26.287  55.827  58.296  1.00 91.92           O
ATOM   1162  N   LYS A 202      26.484  54.191  56.808  1.00 86.56           N
ATOM   1163  CA  LYS A 202      27.501  53.572  57.607  1.00 88.67           C
ATOM   1164  CB  LYS A 202      27.877  52.174  57.083  1.00 94.41           C
ATOM   1165  CG  LYS A 202      26.822  51.052  57.343  1.00101.54           C
ATOM   1166  CD  LYS A 202      25.851  51.384  58.501  1.00102.71           C
ATOM   1167  CE  LYS A 202      25.506  50.163  59.311  1.00103.06           C
ATOM   1168  NZ  LYS A 202      25.834  50.536  60.712  1.00100.79           N
ATOM   1169  C   LYS A 202      28.694  54.485  57.565  1.00 90.80           C
ATOM   1170  O   LYS A 202      29.540  54.468  58.490  1.00 92.48           O
ATOM   1171  N   LEU A 203      28.777  55.282  56.493  1.00 87.19           N
ATOM   1172  CA  LEU A 203      29.948  56.112  56.286  1.00 85.88           C
ATOM   1173  CB  LEU A 203      30.024  56.587  54.856  1.00 86.85           C
ATOM   1174  CG  LEU A 203      30.755  55.658  53.882  1.00 88.45           C
ATOM   1175  CD1 LEU A 203      30.640  56.265  52.526  1.00 89.07           C
ATOM   1176  CD2 LEU A 203      32.229  55.388  54.221  1.00 83.38           C
ATOM   1177  C   LEU A 203      29.906  57.287  57.232  1.00 89.80           C
ATOM   1178  O   LEU A 203      30.866  57.512  57.987  1.00 92.15           O
ATOM   1179  N   ARG A 204      28.780  58.008  57.209  1.00 86.19           N
ATOM   1180  CA  ARG A 204      28.481  59.005  58.199  1.00 85.28           C
ATOM   1181  CB  ARG A 204      27.095  59.558  57.993  1.00 88.54           C
ATOM   1182  CG  ARG A 204      26.812  60.780  58.839  1.00 96.29           C
ATOM   1183  CD  ARG A 204      25.431  61.371  58.542  1.00100.60           C
ATOM   1184  NE  ARG A 204      24.403  60.407  58.868  1.00102.87           N
ATOM   1185  CZ  ARG A 204      23.350  60.159  58.108  1.00108.68           C
ATOM   1186  NH1 ARG A 204      23.158  60.820  56.958  1.00108.27           N
ATOM   1187  NH2 ARG A 204      22.494  59.222  58.499  1.00112.99           N
ATOM   1188  C   ARG A 204      28.593  58.444  59.597  1.00 88.79           C
ATOM   1189  O   ARG A 204      28.989  59.148  60.518  1.00 95.27           O
ATOM   1190  N   GLU A 205      28.252  57.183  59.777  1.00 89.95           N
ATOM   1191  CA  GLU A 205      28.418  56.578  61.085  1.00 97.15           C
ATOM   1192  CB  GLU A 205      27.655  55.255  61.155  1.00101.68           C
ATOM   1193  CG  GLU A 205      27.336  54.748  62.591  1.00107.41           C
ATOM   1194  CD  GLU A 205      26.811  53.311  62.596  1.00108.44           C
ATOM   1195  OE1 GLU A 205      25.928  53.017  61.716  1.00110.51           O
ATOM   1196  OE2 GLU A 205      27.306  52.493  63.448  1.00110.55           O
ATOM   1197  C   GLU A 205      29.898  56.404  61.506  1.00 93.83           C
ATOM   1198  O   GLU A 205      30.241  56.576  62.681  1.00 91.05           O
ATOM   1199  N   ALA A 206      30.776  56.068  60.563  1.00 91.91           N
ATOM   1200  CA  ALA A 206      32.193  55.915  60.911  1.00 90.12           C
ATOM   1201  CB  ALA A 206      32.908  55.116  59.886  1.00 84.27           C
ATOM   1202  C   ALA A 206      32.861  57.286  61.113  1.00 92.81           C
ATOM   1203  O   ALA A 206      33.810  57.430  61.916  1.00 91.50           O
ATOM   1204  N   ALA A 207      32.337  58.292  60.406  1.00 92.55           N
ATOM   1205  CA  ALA A 207      32.838  59.658  60.500  1.00 91.23           C
ATOM   1206  CB  ALA A 207      32.264  60.495  59.424  1.00 93.58           C
ATOM   1207  C   ALA A 207      32.518  60.277  61.832  1.00 94.04           C
ATOM   1208  O   ALA A 207      33.232  61.189  62.290  1.00 96.12           O
ATOM   1209  N   GLU A 208      31.433  59.819  62.445  1.00 95.43           N
ATOM   1210  CA  GLU A 208      31.159  60.249  63.786  1.00 99.75           C
ATOM   1211  CB  GLU A 208      29.749  59.972  64.186  1.00107.59           C
ATOM   1212  CG  GLU A 208      28.913  61.173  64.006  1.00118.74           C
ATOM   1213  CD  GLU A 208      27.474  60.800  63.841  1.00125.44           C
ATOM   1214  OE1 GLU A 208      27.132  59.622  64.170  1.00126.77           O
ATOM   1215  OE2 GLU A 208      26.711  61.689  63.366  1.00127.92           O
ATOM   1216  C   GLU A 208      32.098  59.597  64.742  1.00 98.66           C
ATOM   1217  O   GLU A 208      32.731  60.288  65.536  1.00102.67           O
ATOM   1218  N   ILE A 209      32.224  58.279  64.657  1.00 93.60           N
ATOM   1219  CA  ILE A 209      33.067  57.587  65.610  1.00 91.34           C
ATOM   1220  CB  ILE A 209      33.179  56.138  65.340  1.00 90.05           C
ATOM   1221  CG1 ILE A 209      31.820  55.513  65.153  1.00 91.15           C
ATOM   1222  CD1 ILE A 209      31.924  53.999  65.164  1.00 95.49           C
ATOM   1223  CG2 ILE A 209      33.921  55.489  66.467  1.00 86.90           C
ATOM   1224  C   ILE A 209      34.498  58.052  65.552  1.00 90.59           C
ATOM   1225  O   ILE A 209      35.150  58.177  66.599  1.00 88.14           O
ATOM   1226  N   ILE A 210      35.003  58.265  64.335  1.00 90.82           N
ATOM   1227  CA  ILE A 210      36.380  58.742  64.189  1.00 93.28           C
ATOM   1228  CB  ILE A 210      36.877  58.678  62.720  1.00 93.76           C
ATOM   1229  CG1 ILE A 210      38.373  58.891  62.632  1.00 97.32           C
ATOM   1230  CD1 ILE A 210      38.770  60.408  62.307  1.00101.21           C
ATOM   1231  CG2 ILE A 210      36.294  59.796  61.910  1.00 97.34           C
ATOM   1232  C   ILE A 210      36.539  60.135  64.858  1.00 93.16           C
ATOM   1233  O   ILE A 210      37.544  60.400  65.523  1.00 89.77           O
ATOM   1234  N   SER A 211      35.531  60.998  64.729  1.00 94.58           N
ATOM   1235  CA  SER A 211      35.637  62.315  65.327  1.00 95.84           C
ATOM   1236  CB  SER A 211      34.570  63.262  64.821  1.00 94.13           C
ATOM   1237  OG  SER A 211      34.610  64.384  65.697  1.00 94.41           O
ATOM   1238  C   SER A 211      35.589  62.270  66.851  1.00 95.40           C
ATOM   1239  O   SER A 211      36.406  62.882  67.536  1.00 95.38           O
ATOM   1240  N   GLU A 212      34.629  61.525  67.371  1.00 97.26           N
ATOM   1241  CA  GLU A 212      34.426  61.442  68.801  1.00 98.73           C
ATOM   1242  CB  GLU A 212      33.077  60.776  69.100  1.00101.10           C
ATOM   1243  CG  GLU A 212      32.768  60.582  70.571  1.00108.38           C
ATOM   1244  CD  GLU A 212      32.628  61.902  71.338  1.00114.08           C
ATOM   1245  OE1 GLU A 212      32.304  62.921  70.679  1.00116.08           O
ATOM   1246  OE2 GLU A 212      32.835  61.912  72.592  1.00114.27           O
ATOM   1247  C   GLU A 212      35.576  60.710  69.490  1.00 98.52           C
ATOM   1248  O   GLU A 212      35.843  60.948  70.656  1.00 94.94           O
ATOM   1249  N   HIS A 213      36.241  59.809  68.769  1.00103.42           N
ATOM   1250  CA  HIS A 213      37.294  58.951  69.344  1.00105.55           C
ATOM   1251  CB  HIS A 213      36.828  57.502  69.458  1.00100.71           C
ATOM   1252  CG  HIS A 213      35.706  57.322  70.431  1.00 98.80           C
ATOM   1253  ND1 HIS A 213      35.897  57.352  71.799  1.00 95.01           N
ATOM   1254  CE1 HIS A 213      34.732  57.203  72.400  1.00 97.26           C
ATOM   1255  NE2 HIS A 213      33.794  57.075  71.474  1.00 97.83           N
ATOM   1256  CD2 HIS A 213      34.375  57.147  70.234  1.00 96.09           C
ATOM   1257  C   HIS A 213      38.512  59.003  68.475  1.00111.77           C
ATOM   1258  O   HIS A 213      38.780  58.020  67.750  1.00114.49           O
ATOM   1259  N   PRO A 214      39.255  60.143  68.536  1.00113.06           N
ATOM   1260  CA  PRO A 214      40.326  60.386  67.578  1.00112.60           C
ATOM   1261  CB  PRO A 214      41.108  61.525  68.233  1.00111.15           C
ATOM   1262  CG  PRO A 214      40.083  62.279  69.023  1.00111.37           C
ATOM   1263  CD  PRO A 214      39.139  61.240  69.525  1.00111.57           C
ATOM   1264  C   PRO A 214      41.176  59.114  67.414  1.00116.52           C
ATOM   1265  O   PRO A 214      41.469  58.687  66.301  1.00117.87           O
ATOM   1266  N   MET A 215      41.461  58.463  68.531  1.00121.67           N
ATOM   1267  CA  MET A 215      42.400  57.364  68.586  1.00125.10           C
ATOM   1268  CB  MET A 215      42.754  57.084  70.042  1.00129.83           C
ATOM   1269  CG  MET A 215      44.148  56.509  70.205  1.00131.22           C
ATOM   1270  SD  MET A 215      45.385  57.806  70.261  1.00132.15           S
ATOM   1271  CE  MET A 215      44.838  58.977  68.975  1.00128.32           C
ATOM   1272  C   MET A 215      41.945  56.058  67.976  1.00126.89           C
ATOM   1273  O   MET A 215      42.762  55.146  67.825  1.00127.09           O
ATOM   1274  N   ALA A 216      40.653  55.949  67.660  1.00129.34           N
ATOM   1275  CA  ALA A 216      40.059  54.673  67.234  1.00127.95           C
ATOM   1276  CB  ALA A 216      38.568  54.829  67.024  1.00125.59           C
ATOM   1277  C   ALA A 216      40.750  54.029  66.005  1.00127.42           C
ATOM   1278  O   ALA A 216      40.852  52.809  65.929  1.00128.64           O
ATOM   1279  N   LEU A 217      41.250  54.841  65.073  1.00128.21           N
ATOM   1280  CA  LEU A 217      42.052  54.336  63.951  1.00129.53           C
ATOM   1281  CB  LEU A 217      42.046  55.331  62.772  1.00124.34           C
ATOM   1282  CG  LEU A 217      40.903  55.413  61.746  1.00120.43           C
ATOM   1283  CD1 LEU A 217      41.096  56.568  60.755  1.00118.76           C
ATOM   1284  CD2 LEU A 217      40.721  54.117  60.998  1.00118.32           C
ATOM   1285  C   LEU A 217      43.514  53.978  64.314  1.00136.29           C
ATOM   1286  O   LEU A 217      44.240  53.486  63.462  1.00139.64           O
ATOM   1287  N   GLN A 218      43.961  54.212  65.550  1.00142.65           N
ATOM   1288  CA  GLN A 218      45.380  53.967  65.901  1.00149.11           C
ATOM   1289  CB  GLN A 218      45.883  54.912  66.999  1.00150.31           C
ATOM   1290  CG  GLN A 218      47.411  54.892  67.173  1.00151.23           C
ATOM   1291  CD  GLN A 218      48.092  56.157  66.661  1.00151.82           C
ATOM   1292  OE1 GLN A 218      47.801  56.661  65.567  1.00151.79           O
ATOM   1293  NE2 GLN A 218      49.013  56.675  67.459  1.00151.54           N
ATOM   1294  C   GLN A 218      45.725  52.528  66.285  1.00153.94           C
ATOM   1295  O   GLN A 218      46.510  51.890  65.592  1.00156.42           O
ATOM   1296  N   LEU A 219      45.167  52.038  67.396  1.00158.58           N
ATOM   1297  CA  LEU A 219      45.443  50.678  67.890  1.00162.21           C
ATOM   1298  CB  LEU A 219      44.678  50.397  69.209  1.00164.36           C
ATOM   1299  CG  LEU A 219      44.680  51.473  70.341  1.00167.98           C
ATOM   1300  CD1 LEU A 219      43.371  52.328  70.358  1.00167.14           C
ATOM   1301  CD2 LEU A 219      44.994  50.930  71.789  1.00165.94           C
ATOM   1302  C   LEU A 219      45.193  49.610  66.786  1.00162.49           C
ATOM   1303  O   LEU A 219      45.965  48.657  66.642  1.00159.92           O
ATOM   1304  N   ARG A 220      44.142  49.807  65.986  1.00163.98           N
ATOM   1305  CA  ARG A 220      43.932  49.023  64.766  1.00164.27           C
ATOM   1306  CB  ARG A 220      42.561  49.338  64.141  1.00162.22           C
ATOM   1307  CG  ARG A 220      42.298  48.788  62.739  1.00160.42           C
ATOM   1308  CD  ARG A 220      40.828  48.965  62.392  1.00160.45           C
ATOM   1309  NE  ARG A 220      40.591  49.696  61.138  1.00159.22           N
ATOM   1310  CZ  ARG A 220      39.495  50.427  60.892  1.00159.59           C
ATOM   1311  NH1 ARG A 220      38.558  50.533  61.826  1.00161.00           N
ATOM   1312  NH2 ARG A 220      39.321  51.067  59.732  1.00156.78           N
ATOM   1313  C   ARG A 220      45.109  49.145  63.767  1.00166.02           C
ATOM   1314  O   ARG A 220      45.562  48.125  63.273  1.00168.09           O
ATOM   1315  N   THR A 221      45.625  50.355  63.492  1.00168.00           N
ATOM   1316  CA  THR A 221      46.845  50.515  62.639  1.00169.58           C
ATOM   1317  CB  THR A 221      47.177  52.013  62.198  1.00170.44           C
ATOM   1318  OG1 THR A 221      46.009  52.830  62.212  1.00172.01           O
ATOM   1319  CG2 THR A 221      47.800  52.085  60.785  1.00169.56           C
ATOM   1320  C   THR A 221      48.117  49.966  63.314  1.00172.46           C
ATOM   1321  O   THR A 221      49.133  49.786  62.647  1.00173.30           O
ATOM   1322  N   LEU A 222      48.061  49.696  64.621  1.00175.72           N
ATOM   1323  CA  LEU A 222      49.272  49.373  65.421  1.00177.70           C
ATOM   1324  CB  LEU A 222      49.148  49.967  66.855  1.00177.99           C
ATOM   1325  CG  LEU A 222      50.285  50.130  67.892  1.00176.56           C
ATOM   1326  CD1 LEU A 222      51.594  50.672  67.294  1.00175.65           C
ATOM   1327  CD2 LEU A 222      49.814  50.986  69.088  1.00175.71           C
ATOM   1328  C   LEU A 222      49.716  47.878  65.426  1.00179.94           C
ATOM   1329  O   LEU A 222      50.789  47.561  65.972  1.00181.49           O
ATOM   1330  N   GLN A 223      48.911  46.987  64.814  1.00179.64           N
ATOM   1331  CA  GLN A 223      49.285  45.561  64.570  1.00176.88           C
ATOM   1332  CB  GLN A 223      48.280  44.598  65.225  1.00174.38           C
ATOM   1333  CG  GLN A 223      48.389  44.503  66.741  1.00173.22           C
ATOM   1334  CD  GLN A 223      47.055  44.191  67.414  1.00173.39           C
ATOM   1335  OE1 GLN A 223      46.136  43.647  66.792  1.00172.67           O
ATOM   1336  NE2 GLN A 223      46.942  44.545  68.692  1.00172.15           N
ATOM   1337  C   GLN A 223      49.494  45.190  63.074  1.00176.00           C
ATOM   1338  O   GLN A 223      49.305  44.028  62.695  1.00175.18           O
ATOM   1339  N   THR A 224      49.872  46.184  62.252  1.00175.56           N
ATOM   1340  CA  THR A 224      50.288  46.018  60.835  1.00174.21           C
ATOM   1341  CB  THR A 224      49.591  47.072  59.887  1.00173.71           C
ATOM   1342  OG1 THR A 224      48.317  46.583  59.453  1.00172.79           O
ATOM   1343  CG2 THR A 224      50.451  47.410  58.643  1.00172.30           C
ATOM   1344  C   THR A 224      51.811  46.154  60.698  1.00172.55           C
ATOM   1345  O   THR A 224      52.572  45.346  61.295  1.00170.39           O
TER
ATOM   1346  N   MET B  55      -8.675  33.311  18.408  1.00120.56           N
ATOM   1347  CA  MET B  55      -7.421  33.767  19.071  1.00118.72           C
ATOM   1348  CB  MET B  55      -7.394  33.232  20.511  1.00117.26           C
ATOM   1349  CG  MET B  55      -6.309  33.850  21.371  1.00116.53           C
ATOM   1350  SD  MET B  55      -6.933  34.452  22.933  1.00117.36           S
ATOM   1351  CE  MET B  55      -7.338  36.202  22.579  1.00115.98           C
ATOM   1352  C   MET B  55      -6.191  33.314  18.243  1.00118.16           C
ATOM   1353  O   MET B  55      -6.006  32.106  18.036  1.00118.91           O
ATOM   1354  N   ILE B  56      -5.377  34.261  17.750  1.00113.59           N
ATOM   1355  CA  ILE B  56      -4.223  33.906  16.878  1.00110.18           C
ATOM   1356  CB  ILE B  56      -4.098  34.828  15.568  1.00111.83           C
ATOM   1357  CG1 ILE B  56      -4.009  36.349  15.884  1.00119.06           C
ATOM   1358  CD1 ILE B  56      -5.399  37.170  16.153  1.00120.35           C
ATOM   1359  CG2 ILE B  56      -5.229  34.554  14.555  1.00109.51           C
ATOM   1360  C   ILE B  56      -2.924  33.869  17.695  1.00104.43           C
ATOM   1361  O   ILE B  56      -2.517  34.876  18.226  1.00109.74           O
ATOM   1362  N   PHE B  57      -2.284  32.719  17.819  1.00 94.76           N
ATOM   1363  CA  PHE B  57      -1.139  32.560  18.737  1.00 90.48           C
ATOM   1364  CB  PHE B  57      -1.262  31.211  19.415  1.00 90.67           C
ATOM   1365  CG  PHE B  57      -2.333  31.144  20.442  1.00 89.82           C
ATOM   1366  CD1 PHE B  57      -3.635  30.974  20.083  1.00 89.22           C
ATOM   1367  CE1 PHE B  57      -4.627  30.877  21.060  1.00 93.68           C
ATOM   1368  CZ  PHE B  57      -4.318  30.956  22.404  1.00 91.70           C
ATOM   1369  CE2 PHE B  57      -3.005  31.117  22.784  1.00 93.87           C
ATOM   1370  CD2 PHE B  57      -2.014  31.202  21.802  1.00 93.53           C
ATOM   1371  C   PHE B  57       0.286  32.613  18.130  1.00 87.76           C
ATOM   1372  O   PHE B  57       0.442  32.348  16.977  1.00 87.65           O
ATOM   1373  N   GLU B  58       1.322  32.933  18.907  1.00 84.70           N
ATOM   1374  CA  GLU B  58       2.691  32.763  18.428  1.00 85.76           C
ATOM   1375  CB  GLU B  58       3.338  34.059  17.950  1.00 89.45           C
ATOM   1376  CG  GLU B  58       2.983  35.324  18.706  1.00 99.68           C
ATOM   1377  CD  GLU B  58       3.244  36.614  17.890  1.00 98.78           C
ATOM   1378  OE1 GLU B  58       2.595  37.649  18.161  1.00101.29           O
ATOM   1379  OE2 GLU B  58       4.104  36.595  16.984  1.00104.00           O
ATOM   1380  C   GLU B  58       3.617  32.029  19.363  1.00 83.40           C
ATOM   1381  O   GLU B  58       3.384  31.944  20.547  1.00 88.05           O
ATOM   1382  N   LYS B  59       4.665  31.465  18.791  1.00 84.08           N
ATOM   1383  CA  LYS B  59       5.604  30.617  19.477  1.00 82.37           C
ATOM   1384  CB  LYS B  59       6.463  29.913  18.424  1.00 87.63           C
ATOM   1385  CG  LYS B  59       7.395  28.788  18.899  1.00 91.97           C
ATOM   1386  CD  LYS B  59       7.092  27.553  18.065  1.00 97.63           C
ATOM   1387  CE  LYS B  59       5.551  27.149  18.166  1.00 99.62           C
ATOM   1388  NZ  LYS B  59       4.842  26.663  16.921  1.00 98.93           N
ATOM   1389  C   LYS B  59       6.469  31.497  20.364  1.00 82.79           C
ATOM   1390  O   LYS B  59       7.292  32.270  19.889  1.00 82.52           O
ATOM   1391  N   ALA B  60       6.264  31.350  21.662  1.00 82.31           N
ATOM   1392  CA  ALA B  60       7.031  32.012  22.692  1.00 79.23           C
ATOM   1393  CB  ALA B  60       6.598  31.490  24.037  1.00 76.02           C
ATOM   1394  C   ALA B  60       8.488  31.702  22.510  1.00 79.82           C
ATOM   1395  O   ALA B  60       8.836  30.513  22.365  1.00 77.29           O
ATOM   1396  N   VAL B  61       9.328  32.758  22.534  1.00 79.28           N
ATOM   1397  CA  VAL B  61      10.786  32.578  22.639  1.00 82.05           C
ATOM   1398  CB  VAL B  61      11.619  33.831  22.249  1.00 79.10           C
ATOM   1399  CG1 VAL B  61      13.107  33.425  21.941  1.00 77.52           C
ATOM   1400  CG2 VAL B  61      11.044  34.502  21.086  1.00 75.35           C
ATOM   1401  C   VAL B  61      11.129  32.210  24.071  1.00 83.20           C
ATOM   1402  O   VAL B  61      10.687  32.888  24.950  1.00 86.44           O
ATOM   1403  N   ILE B  62      11.893  31.146  24.302  1.00 84.58           N
ATOM   1404  CA  ILE B  62      12.307  30.788  25.658  1.00 87.84           C
ATOM   1405  CB  ILE B  62      11.426  29.611  26.265  1.00 87.55           C
ATOM   1406  CG1 ILE B  62      12.252  28.372  26.763  1.00 87.42           C
ATOM   1407  CD1 ILE B  62      12.724  27.318  25.750  1.00 88.84           C
ATOM   1408  CG2 ILE B  62      10.207  29.336  25.404  1.00 83.51           C
ATOM   1409  C   ILE B  62      13.805  30.453  25.718  1.00 93.31           C
ATOM   1410  O   ILE B  62      14.425  30.109  24.698  1.00 96.03           O
ATOM   1411  N   VAL B  63      14.389  30.555  26.913  1.00 94.85           N
ATOM   1412  CA  VAL B  63      15.759  30.110  27.124  1.00 91.11           C
ATOM   1413  CB  VAL B  63      16.146  30.243  28.609  1.00 86.55           C
ATOM   1414  CG1 VAL B  63      17.515  29.624  28.883  1.00 82.84           C
ATOM   1415  CG2 VAL B  63      16.089  31.680  29.032  1.00 84.82           C
ATOM   1416  C   VAL B  63      15.807  28.644  26.734  1.00 94.44           C
ATOM   1417  O   VAL B  63      15.470  27.795  27.559  1.00101.01           O
ATOM   1418  N   ASP B  64      16.190  28.339  25.491  1.00 93.98           N
ATOM   1419  CA  ASP B  64      16.284  26.930  25.048  1.00 95.60           C
ATOM   1420  CB  ASP B  64      16.707  26.801  23.578  1.00 92.52           C
ATOM   1421  CG  ASP B  64      15.671  27.366  22.636  1.00 97.59           C
ATOM   1422  OD1 ASP B  64      14.491  26.887  22.632  1.00100.62           O
ATOM   1423  OD2 ASP B  64      16.031  28.313  21.906  1.00 96.08           O
ATOM   1424  C   ASP B  64      17.158  26.065  25.952  1.00 97.82           C
ATOM   1425  O   ASP B  64      18.278  26.462  26.319  1.00 97.12           O
ATOM   1426  N   LEU B  65      16.620  24.897  26.310  1.00101.86           N
ATOM   1427  CA  LEU B  65      17.331  23.918  27.122  1.00109.99           C
ATOM   1428  CB  LEU B  65      16.360  23.085  27.934  1.00112.99           C
ATOM   1429  CG  LEU B  65      16.180  23.399  29.414  1.00117.19           C
ATOM   1430  CD1 LEU B  65      15.771  24.866  29.651  1.00119.67           C
ATOM   1431  CD2 LEU B  65      15.114  22.448  29.976  1.00116.07           C
ATOM   1432  C   LEU B  65      18.153  22.966  26.302  1.00111.19           C
ATOM   1433  O   LEU B  65      19.199  22.549  26.753  1.00112.07           O
ATOM   1434  N   ARG B  66      17.645  22.617  25.116  1.00113.97           N
ATOM   1435  CA  ARG B  66      18.221  21.634  24.182  1.00112.57           C
ATOM   1436  CB  ARG B  66      17.265  20.436  24.095  1.00118.08           C
ATOM   1437  CG  ARG B  66      17.816  19.146  23.487  1.00127.35           C
ATOM   1438  CD  ARG B  66      17.239  17.906  24.207  1.00130.82           C
ATOM   1439  NE  ARG B  66      17.900  17.754  25.510  1.00137.85           N
ATOM   1440  CZ  ARG B  66      17.719  16.746  26.363  1.00140.12           C
ATOM   1441  NH1 ARG B  66      16.877  15.759  26.064  1.00141.89           N
ATOM   1442  NH2 ARG B  66      18.394  16.720  27.519  1.00140.50           N
ATOM   1443  C   ARG B  66      18.326  22.334  22.830  1.00108.72           C
ATOM   1444  O   ARG B  66      17.479  23.163  22.498  1.00111.09           O
ATOM   1445  N   THR B  67      19.336  22.002  22.038  1.00105.49           N
ATOM   1446  CA  THR B  67      19.662  22.779  20.816  1.00101.83           C
ATOM   1447  CB  THR B  67      20.891  22.187  20.109  1.00106.39           C
ATOM   1448  OG1 THR B  67      21.982  22.024  21.048  1.00110.73           O
ATOM   1449  CG2 THR B  67      21.313  23.101  18.973  1.00106.87           C
ATOM   1450  C   THR B  67      18.581  22.885  19.751  1.00 94.52           C
ATOM   1451  O   THR B  67      18.107  21.886  19.325  1.00 94.96           O
ATOM   1452  N   GLN B  68      18.211  24.085  19.319  1.00 92.68           N
ATOM   1453  CA  GLN B  68      17.380  24.277  18.120  1.00 95.91           C
ATOM   1454  CB  GLN B  68      16.734  25.664  18.094  1.00 96.86           C
ATOM   1455  CG  GLN B  68      15.398  25.871  18.884  1.00103.31           C
ATOM   1456  CD  GLN B  68      14.802  27.315  18.645  1.00104.13           C
ATOM   1457  OE1 GLN B  68      14.378  27.644  17.530  1.00110.24           O
ATOM   1458  NE2 GLN B  68      14.806  28.167  19.686  1.00102.68           N
ATOM   1459  C   GLN B  68      18.173  24.039  16.798  1.00 95.70           C
ATOM   1460  O   GLN B  68      19.397  23.903  16.803  1.00 98.66           O
ATOM   1461  N   VAL B  69      17.465  23.971  15.666  1.00 95.72           N
ATOM   1462  CA  VAL B  69      18.033  23.493  14.389  1.00 90.80           C
ATOM   1463  CB  VAL B  69      17.681  22.013  14.162  1.00 87.28           C
ATOM   1464  CG1 VAL B  69      17.853  21.672  12.750  1.00 91.22           C
ATOM   1465  CG2 VAL B  69      18.599  21.140  14.928  1.00 88.66           C
ATOM   1466  C   VAL B  69      17.452  24.263  13.217  1.00 88.74           C
ATOM   1467  O   VAL B  69      16.293  24.118  12.932  1.00 92.01           O
ATOM   1468  N   LEU B  70      18.231  25.084  12.537  1.00 88.06           N
ATOM   1469  CA  LEU B  70      17.690  25.850  11.419  1.00 90.16           C
ATOM   1470  CB  LEU B  70      18.071  27.313  11.552  1.00 90.73           C
ATOM   1471  CG  LEU B  70      17.226  28.230  10.696  1.00 93.88           C
ATOM   1472  CD1 LEU B  70      15.738  27.867  10.886  1.00100.37           C
ATOM   1473  CD2 LEU B  70      17.460  29.674  11.056  1.00 94.34           C
ATOM   1474  C   LEU B  70      18.214  25.301  10.100  1.00 94.37           C
ATOM   1475  O   LEU B  70      19.379  24.863  10.029  1.00 99.22           O
ATOM   1476  N   ASP B  71      17.386  25.291   9.057  1.00 90.59           N
ATOM   1477  CA  ASP B  71      17.883  24.768   7.790  1.00 91.46           C
ATOM   1478  CB  ASP B  71      16.846  23.882   7.102  1.00 95.43           C
ATOM   1479  CG  ASP B  71      16.593  22.611   7.859  1.00102.89           C
ATOM   1480  OD1 ASP B  71      17.487  21.760   7.930  1.00110.58           O
ATOM   1481  OD2 ASP B  71      15.509  22.450   8.432  1.00109.82           O
ATOM   1482  C   ASP B  71      18.196  25.968   6.970  1.00 88.14           C
ATOM   1483  O   ASP B  71      17.355  26.820   6.866  1.00 90.86           O
ATOM   1484  N   VAL B  72      19.394  26.083   6.415  1.00 85.94           N
ATOM   1485  CA  VAL B  72      19.667  27.251   5.588  1.00 86.98           C
ATOM   1486  CB  VAL B  72      21.155  27.613   5.538  1.00 89.57           C
ATOM   1487  CG1 VAL B  72      21.345  28.820   4.689  1.00 91.04           C
ATOM   1488  CG2 VAL B  72      21.704  27.907   6.924  1.00 90.17           C
ATOM   1489  C   VAL B  72      19.195  26.893   4.197  1.00 88.38           C
ATOM   1490  O   VAL B  72      19.570  25.831   3.703  1.00 89.96           O
ATOM   1491  N   PRO B  73      18.352  27.750   3.559  1.00 89.91           N
ATOM   1492  CA  PRO B  73      17.832  27.384   2.234  1.00 90.05           C
ATOM   1493  CB  PRO B  73      16.882  28.549   1.892  1.00 85.59           C
ATOM   1494  CG  PRO B  73      16.577  29.179   3.132  1.00 83.84           C
ATOM   1495  CD  PRO B  73      17.817  29.059   3.973  1.00 86.99           C
ATOM   1496  C   PRO B  73      18.982  27.320   1.235  1.00 92.05           C
ATOM   1497  O   PRO B  73      20.013  27.955   1.469  1.00 92.86           O
ATOM   1498  N   VAL B  74      18.812  26.565   0.142  1.00 93.19           N
ATOM   1499  CA  VAL B  74      19.893  26.331  -0.842  1.00 89.08           C
ATOM   1500  CB  VAL B  74      19.417  25.352  -1.948  1.00 86.52           C
ATOM   1501  CG1 VAL B  74      20.195  25.550  -3.169  1.00 89.43           C
ATOM   1502  CG2 VAL B  74      19.623  23.914  -1.514  1.00 88.23           C
ATOM   1503  C   VAL B  74      20.479  27.626  -1.435  1.00 86.74           C
ATOM   1504  O   VAL B  74      19.758  28.567  -1.718  1.00 86.52           O
ATOM   1505  N   GLN B  75      21.791  27.687  -1.586  1.00 86.77           N
ATOM   1506  CA  GLN B  75      22.411  28.781  -2.355  1.00 88.85           C
ATOM   1507  CB  GLN B  75      23.522  29.514  -1.558  1.00 86.96           C
ATOM   1508  CG  GLN B  75      23.139  30.039  -0.163  1.00 84.57           C
ATOM   1509  CD  GLN B  75      21.937  30.940  -0.227  1.00 89.36           C
ATOM   1510  OE1 GLN B  75      21.992  32.013  -0.810  1.00 91.91           O
ATOM   1511  NE2 GLN B  75      20.832  30.497   0.340  1.00 90.49           N
ATOM   1512  C   GLN B  75      23.012  28.218  -3.629  1.00 89.43           C
ATOM   1513  O   GLN B  75      23.845  27.322  -3.585  1.00 87.72           O
ATOM   1514  N   GLU B  76      22.580  28.721  -4.770  1.00 94.52           N
ATOM   1515  CA  GLU B  76      23.297  28.420  -6.003  1.00100.36           C
ATOM   1516  CB  GLU B  76      22.338  28.295  -7.214  1.00100.66           C
ATOM   1517  CG  GLU B  76      22.964  27.499  -8.386  1.00111.61           C
ATOM   1518  CD  GLU B  76      22.170  27.515  -9.716  1.00113.44           C
ATOM   1519  OE1 GLU B  76      22.804  27.591 -10.824  1.00118.16           O
ATOM   1520  OE2 GLU B  76      20.925  27.417  -9.646  1.00117.54           O
ATOM   1521  C   GLU B  76      24.371  29.511  -6.203  1.00 95.70           C
ATOM   1522  O   GLU B  76      24.048  30.692  -6.308  1.00 98.02           O
ATOM   1523  N   THR B  77      25.640  29.120  -6.228  1.00 92.26           N
ATOM   1524  CA  THR B  77      26.738  30.060  -6.501  1.00 93.16           C
ATOM   1525  CB  THR B  77      27.085  30.913  -5.245  1.00 91.98           C
ATOM   1526  OG1 THR B  77      27.855  32.033  -5.647  1.00 96.17           O
ATOM   1527  CG2 THR B  77      27.901  30.164  -4.247  1.00 92.37           C
ATOM   1528  C   THR B  77      28.001  29.404  -7.127  1.00 94.50           C
ATOM   1529  O   THR B  77      28.085  28.172  -7.246  1.00 96.60           O
ATOM   1530  N   ILE B  78      28.981  30.208  -7.533  1.00 94.70           N
ATOM   1531  CA  ILE B  78      30.197  29.637  -8.122  1.00 98.57           C
ATOM   1532  CB  ILE B  78      30.733  30.480  -9.274  1.00100.55           C
ATOM   1533  CG1 ILE B  78      29.639  30.761 -10.315  1.00106.71           C
ATOM   1534  CD1 ILE B  78      29.734  32.179 -11.043  1.00110.88           C
ATOM   1535  CG2 ILE B  78      31.793  29.713  -9.959  1.00 99.77           C
ATOM   1536  C   ILE B  78      31.272  29.513  -7.052  1.00 98.56           C
ATOM   1537  O   ILE B  78      31.248  30.295  -6.093  1.00102.97           O
ATOM   1538  N   THR B  79      32.192  28.548  -7.174  1.00 95.57           N
ATOM   1539  CA  THR B  79      33.261  28.433  -6.165  1.00 96.36           C
ATOM   1540  CB  THR B  79      33.772  27.008  -5.919  1.00 96.36           C
ATOM   1541  OG1 THR B  79      34.369  26.475  -7.105  1.00 97.04           O
ATOM   1542  CG2 THR B  79      32.644  26.112  -5.427  1.00 96.49           C
ATOM   1543  C   THR B  79      34.406  29.266  -6.613  1.00 98.13           C
ATOM   1544  O   THR B  79      34.379  29.762  -7.733  1.00100.28           O
ATOM   1545  N   LYS B  80      35.406  29.434  -5.751  1.00100.90           N
ATOM   1546  CA  LYS B  80      36.585  30.219  -6.130  1.00106.99           C
ATOM   1547  CB  LYS B  80      37.599  30.267  -4.995  1.00114.47           C
ATOM   1548  CG  LYS B  80      38.671  31.334  -5.176  1.00123.15           C
ATOM   1549  CD  LYS B  80      39.585  31.407  -3.954  1.00129.04           C
ATOM   1550  CE  LYS B  80      41.062  31.527  -4.347  1.00132.50           C
ATOM   1551  NZ  LYS B  80      41.887  31.817  -3.135  1.00135.15           N
ATOM   1552  C   LYS B  80      37.214  29.634  -7.391  1.00105.09           C
ATOM   1553  O   LYS B  80      37.494  30.366  -8.313  1.00104.02           O
ATOM   1554  N   ASP B  81      37.426  28.312  -7.379  1.00105.46           N
ATOM   1555  CA  ASP B  81      37.700  27.431  -8.520  1.00100.11           C
ATOM   1556  CB  ASP B  81      37.328  25.998  -8.126  1.00104.13           C
ATOM   1557  CG  ASP B  81      38.482  25.203  -7.588  1.00107.10           C
ATOM   1558  OD1 ASP B  81      39.595  25.390  -8.082  1.00111.25           O
ATOM   1559  OD2 ASP B  81      38.277  24.349  -6.700  1.00107.19           O
ATOM   1560  C   ASP B  81      36.868  27.682  -9.744  1.00 99.98           C
ATOM   1561  O   ASP B  81      37.202  27.185 -10.787  1.00104.05           O
ATOM   1562  N   ASN B  82      35.731  28.349  -9.617  1.00 99.95           N
ATOM   1563  CA  ASN B  82      34.809  28.520 -10.749  1.00104.06           C
ATOM   1564  CB  ASN B  82      35.546  29.010 -11.991  1.00110.18           C
ATOM   1565  CG  ASN B  82      35.332  30.477 -12.230  1.00116.43           C
ATOM   1566  OD1 ASN B  82      34.194  30.942 -12.499  1.00118.61           O
ATOM   1567  ND2 ASN B  82      36.424  31.236 -12.140  1.00117.93           N
ATOM   1568  C   ASN B  82      33.807  27.397 -11.136  1.00103.23           C
ATOM   1569  O   ASN B  82      33.247  27.389 -12.266  1.00100.28           O
ATOM   1570  N   VAL B  83      33.536  26.493 -10.197  1.00 99.68           N
ATOM   1571  CA  VAL B  83      32.562  25.437 -10.438  1.00 95.06           C
ATOM   1572  CB  VAL B  83      32.927  24.244  -9.659  1.00 97.56           C
ATOM   1573  CG1 VAL B  83      32.041  23.062 -10.098  1.00101.58           C
ATOM   1574  CG2 VAL B  83      34.424  23.988  -9.804  1.00 94.08           C
ATOM   1575  C   VAL B  83      31.178  25.822  -9.963  1.00 91.48           C
ATOM   1576  O   VAL B  83      31.012  26.282  -8.835  1.00 94.23           O
ATOM   1577  N   PRO B  84      30.166  25.635 -10.807  1.00 86.46           N
ATOM   1578  CA  PRO B  84      28.857  26.055 -10.301  1.00 84.60           C
ATOM   1579  CB  PRO B  84      28.033  26.290 -11.584  1.00 84.03           C
ATOM   1580  CG  PRO B  84      28.621  25.367 -12.598  1.00 83.97           C
ATOM   1581  CD  PRO B  84      30.092  25.077 -12.165  1.00 85.02           C
ATOM   1582  C   PRO B  84      28.240  24.993  -9.351  1.00 83.23           C
ATOM   1583  O   PRO B  84      28.403  23.782  -9.507  1.00 82.57           O
ATOM   1584  N   VAL B  85      27.526  25.457  -8.352  1.00 82.35           N
ATOM   1585  CA  VAL B  85      27.289  24.619  -7.220  1.00 77.29           C
ATOM   1586  CB  VAL B  85      28.506  24.738  -6.399  1.00 73.67           C
ATOM   1587  CG1 VAL B  85      28.171  24.956  -4.998  1.00 71.52           C
ATOM   1588  CG2 VAL B  85      29.433  23.547  -6.695  1.00 72.73           C
ATOM   1589  C   VAL B  85      26.050  25.010  -6.431  1.00 79.22           C
ATOM   1590  O   VAL B  85      25.741  26.198  -6.301  1.00 77.14           O
ATOM   1591  N   ARG B  86      25.318  24.008  -5.941  1.00 81.25           N
ATOM   1592  CA  ARG B  86      24.168  24.261  -5.061  1.00 82.76           C
ATOM   1593  CB  ARG B  86      22.881  23.634  -5.595  1.00 79.19           C
ATOM   1594  CG  ARG B  86      22.437  24.378  -6.870  1.00 88.50           C
ATOM   1595  CD  ARG B  86      21.087  24.021  -7.560  1.00 87.80           C
ATOM   1596  NE  ARG B  86      19.981  24.460  -6.743  1.00 93.00           N
ATOM   1597  CZ  ARG B  86      19.024  23.656  -6.328  1.00 95.70           C
ATOM   1598  NH1 ARG B  86      18.996  22.379  -6.732  1.00 97.58           N
ATOM   1599  NH2 ARG B  86      18.085  24.152  -5.547  1.00 96.88           N
ATOM   1600  C   ARG B  86      24.545  23.730  -3.718  1.00 82.74           C
ATOM   1601  O   ARG B  86      24.941  22.580  -3.605  1.00 86.33           O
ATOM   1602  N   VAL B  87      24.506  24.580  -2.701  1.00 81.69           N
ATOM   1603  CA  VAL B  87      24.890  24.114  -1.379  1.00 81.20           C
ATOM   1604  CB  VAL B  87      26.215  24.646  -1.019  1.00 77.02           C
ATOM   1605  CG1 VAL B  87      26.564  24.169   0.357  1.00 80.59           C
ATOM   1606  CG2 VAL B  87      27.180  24.109  -1.945  1.00 75.74           C
ATOM   1607  C   VAL B  87      23.919  24.471  -0.268  1.00 82.29           C
ATOM   1608  O   VAL B  87      23.170  25.454  -0.392  1.00 80.83           O
ATOM   1609  N   ASN B  88      23.902  23.668   0.801  1.00 82.13           N
ATOM   1610  CA  ASN B  88      23.164  24.086   2.021  1.00 85.58           C
ATOM   1611  CB  ASN B  88      21.674  23.840   1.927  1.00 84.24           C
ATOM   1612  CG  ASN B  88      21.364  22.431   1.750  1.00 84.59           C
ATOM   1613  OD1 ASN B  88      22.217  21.564   1.942  1.00 85.28           O
ATOM   1614  ND2 ASN B  88      20.146  22.165   1.336  1.00 86.90           N
ATOM   1615  C   ASN B  88      23.632  23.585   3.365  1.00 86.45           C
ATOM   1616  O   ASN B  88      24.542  22.755   3.465  1.00 92.32           O
ATOM   1617  N   ALA B  89      22.999  24.082   4.414  1.00 82.05           N
ATOM   1618  CA  ALA B  89      23.646  23.944   5.676  1.00 84.06           C
ATOM   1619  CB  ALA B  89      24.587  25.115   5.880  1.00 85.42           C
ATOM   1620  C   ALA B  89      22.661  23.901   6.786  1.00 86.11           C
ATOM   1621  O   ALA B  89      21.595  24.565   6.708  1.00 85.16           O
ATOM   1622  N   VAL B  90      23.021  23.147   7.831  1.00 83.87           N
ATOM   1623  CA  VAL B  90      22.294  23.293   9.086  1.00 87.67           C
ATOM   1624  CB  VAL B  90      21.761  21.931   9.621  1.00 89.26           C
ATOM   1625  CG1 VAL B  90      21.320  22.023  11.088  1.00 91.92           C
ATOM   1626  CG2 VAL B  90      20.562  21.514   8.796  1.00 88.33           C
ATOM   1627  C   VAL B  90      23.004  24.166  10.144  1.00 85.63           C
ATOM   1628  O   VAL B  90      24.208  24.028  10.378  1.00 81.18           O
ATOM   1629  N   VAL B  91      22.229  25.087  10.731  1.00 85.11           N
ATOM   1630  CA  VAL B  91      22.654  25.903  11.883  1.00 87.02           C
ATOM   1631  CB  VAL B  91      22.192  27.376  11.730  1.00 81.44           C
ATOM   1632  CG1 VAL B  91      22.616  28.165  12.936  1.00 78.48           C
ATOM   1633  CG2 VAL B  91      22.739  27.991  10.458  1.00 79.10           C
ATOM   1634  C   VAL B  91      22.137  25.358  13.261  1.00 92.36           C
ATOM   1635  O   VAL B  91      20.926  25.426  13.575  1.00 96.50           O
ATOM   1636  N   TYR B  92      23.035  24.848  14.099  1.00 89.36           N
ATOM   1637  CA  TYR B  92      22.603  24.465  15.431  1.00 90.99           C
ATOM   1638  CB  TYR B  92      23.434  23.298  15.906  1.00 92.17           C
ATOM   1639  CG  TYR B  92      23.259  22.143  14.990  1.00 92.22           C
ATOM   1640  CD1 TYR B  92      23.991  22.060  13.820  1.00 93.40           C
ATOM   1641  CE1 TYR B  92      23.812  21.011  12.951  1.00 95.69           C
ATOM   1642  CZ  TYR B  92      22.872  20.041  13.248  1.00 94.23           C
ATOM   1643  OH  TYR B  92      22.716  19.015  12.387  1.00 94.09           O
ATOM   1644  CE2 TYR B  92      22.117  20.103  14.386  1.00 92.65           C
ATOM   1645  CD2 TYR B  92      22.319  21.160  15.257  1.00 92.80           C
ATOM   1646  C   TYR B  92      22.691  25.638  16.406  1.00 93.81           C
ATOM   1647  O   TYR B  92      23.747  26.250  16.515  1.00 96.99           O
ATOM   1648  N   PHE B  93      21.607  25.961  17.119  1.00 90.50           N
ATOM   1649  CA  PHE B  93      21.652  27.083  18.052  1.00 89.90           C
ATOM   1650  CB  PHE B  93      21.268  28.352  17.319  1.00 88.41           C
ATOM   1651  CG  PHE B  93      19.834  28.414  16.954  1.00 87.23           C
ATOM   1652  CD1 PHE B  93      18.949  29.151  17.714  1.00 84.32           C
ATOM   1653  CE1 PHE B  93      17.558  29.211  17.356  1.00 88.21           C
ATOM   1654  CZ  PHE B  93      17.078  28.522  16.244  1.00 85.88           C
ATOM   1655  CE2 PHE B  93      17.978  27.779  15.481  1.00 90.47           C
ATOM   1656  CD2 PHE B  93      19.354  27.726  15.835  1.00 90.06           C
ATOM   1657  C   PHE B  93      20.757  26.985  19.276  1.00 93.04           C
ATOM   1658  O   PHE B  93      19.677  26.436  19.179  1.00 94.95           O
ATOM   1659  N   ARG B  94      21.185  27.556  20.412  1.00 94.29           N
ATOM   1660  CA  ARG B  94      20.280  27.783  21.541  1.00 95.03           C
ATOM   1661  CB  ARG B  94      20.838  27.198  22.845  1.00 95.56           C
ATOM   1662  CG  ARG B  94      21.163  25.688  22.768  1.00105.45           C
ATOM   1663  CD  ARG B  94      22.261  25.212  23.724  1.00110.77           C
ATOM   1664  NE  ARG B  94      21.808  25.218  25.124  1.00128.78           N
ATOM   1665  CZ  ARG B  94      22.230  24.372  26.088  1.00136.60           C
ATOM   1666  NH1 ARG B  94      23.136  23.412  25.816  1.00139.47           N
ATOM   1667  NH2 ARG B  94      21.747  24.472  27.345  1.00135.50           N
ATOM   1668  C   ARG B  94      19.988  29.271  21.679  1.00 91.17           C
ATOM   1669  O   ARG B  94      20.835  30.106  21.393  1.00 92.61           O
ATOM   1670  N   VAL B  95      18.764  29.613  22.065  1.00 90.69           N
ATOM   1671  CA  VAL B  95      18.501  30.928  22.639  1.00 87.79           C
ATOM   1672  CB  VAL B  95      17.010  31.275  22.696  1.00 88.28           C
ATOM   1673  CG1 VAL B  95      16.783  32.627  23.370  1.00 89.57           C
ATOM   1674  CG2 VAL B  95      16.453  31.323  21.334  1.00 89.83           C
ATOM   1675  C   VAL B  95      19.066  30.962  24.063  1.00 88.39           C
ATOM   1676  O   VAL B  95      18.996  29.999  24.845  1.00 85.39           O
ATOM   1677  N   VAL B  96      19.649  32.099  24.384  1.00 92.00           N
ATOM   1678  CA  VAL B  96      20.308  32.275  25.648  1.00 89.04           C
ATOM   1679  CB  VAL B  96      21.816  32.368  25.445  1.00 85.74           C
ATOM   1680  CG1 VAL B  96      22.472  32.846  26.689  1.00 91.30           C
ATOM   1681  CG2 VAL B  96      22.369  30.998  25.079  1.00 80.16           C
ATOM   1682  C   VAL B  96      19.684  33.462  26.399  1.00 90.78           C
ATOM   1683  O   VAL B  96      19.541  33.379  27.626  1.00 94.42           O
ATOM   1684  N   ASP B  97      19.257  34.499  25.669  1.00 89.06           N
ATOM   1685  CA  ASP B  97      18.603  35.663  26.249  1.00 89.26           C
ATOM   1686  CB  ASP B  97      19.596  36.849  26.317  1.00 95.26           C
ATOM   1687  CG  ASP B  97      18.986  38.206  26.897  1.00 97.83           C
ATOM   1688  OD1 ASP B  97      17.716  38.418  27.036  1.00 94.95           O
ATOM   1689  OD2 ASP B  97      19.885  39.070  27.198  1.00 96.79           O
ATOM   1690  C   ASP B  97      17.362  35.977  25.424  1.00 91.47           C
ATOM   1691  O   ASP B  97      17.403  36.700  24.416  1.00 91.05           O
ATOM   1692  N   PRO B  98      16.231  35.409  25.836  1.00 93.86           N
ATOM   1693  CA  PRO B  98      14.953  35.719  25.168  1.00 95.41           C
ATOM   1694  CB  PRO B  98      13.904  35.233  26.156  1.00 90.82           C
ATOM   1695  CG  PRO B  98      14.593  34.114  26.877  1.00 93.48           C
ATOM   1696  CD  PRO B  98      16.079  34.419  26.914  1.00 91.34           C
ATOM   1697  C   PRO B  98      14.782  37.195  24.938  1.00 98.06           C
ATOM   1698  O   PRO B  98      14.512  37.586  23.830  1.00103.57           O
ATOM   1699  N   VAL B  99      14.985  37.999  25.976  1.00103.91           N
ATOM   1700  CA  VAL B  99      14.669  39.428  25.943  1.00104.93           C
ATOM   1701  CB  VAL B  99      14.872  40.178  27.338  1.00104.46           C
ATOM   1702  CG1 VAL B  99      14.081  41.471  27.372  1.00100.80           C
ATOM   1703  CG2 VAL B  99      14.454  39.307  28.546  1.00103.97           C
ATOM   1704  C   VAL B  99      15.493  40.053  24.823  1.00104.53           C
ATOM   1705  O   VAL B  99      14.946  40.803  24.003  1.00101.91           O
ATOM   1706  N   LYS B 100      16.781  39.712  24.746  1.00101.67           N
ATOM   1707  CA  LYS B 100      17.545  40.163  23.587  1.00103.91           C
ATOM   1708  CB  LYS B 100      18.959  39.594  23.552  1.00105.26           C
ATOM   1709  CG  LYS B 100      20.009  40.362  24.336  1.00112.88           C
ATOM   1710  CD  LYS B 100      21.440  39.876  23.916  1.00118.15           C
ATOM   1711  CE  LYS B 100      22.402  39.538  25.106  1.00125.48           C
ATOM   1712  NZ  LYS B 100      22.995  40.777  25.725  1.00129.45           N
ATOM   1713  C   LYS B 100      16.789  39.824  22.294  1.00 96.61           C
ATOM   1714  O   LYS B 100      16.510  40.725  21.529  1.00 92.93           O
ATOM   1715  N   ALA B 101      16.413  38.543  22.117  1.00 91.73           N
ATOM   1716  CA  ALA B 101      15.869  37.949  20.862  1.00 86.09           C
ATOM   1717  CB  ALA B 101      15.845  36.477  21.003  1.00 83.88           C
ATOM   1718  C   ALA B 101      14.481  38.406  20.403  1.00 87.95           C
ATOM   1719  O   ALA B 101      14.156  38.435  19.209  1.00 91.14           O
ATOM   1720  N   VAL B 102      13.623  38.718  21.349  1.00 89.38           N
ATOM   1721  CA  VAL B 102      12.301  39.175  21.014  1.00 87.39           C
ATOM   1722  CB  VAL B 102      11.382  39.002  22.217  1.00 87.70           C
ATOM   1723  CG1 VAL B 102       9.909  39.274  21.840  1.00 89.45           C
ATOM   1724  CG2 VAL B 102      11.561  37.623  22.782  1.00 86.04           C
ATOM   1725  C   VAL B 102      12.367  40.641  20.643  1.00 88.61           C
ATOM   1726  O   VAL B 102      11.525  41.129  19.909  1.00 92.57           O
ATOM   1727  N   THR B 103      13.408  41.316  21.114  1.00 91.13           N
ATOM   1728  CA  THR B 103      13.392  42.756  21.316  1.00 91.13           C
ATOM   1729  CB  THR B 103      13.665  43.038  22.831  1.00 94.20           C
ATOM   1730  OG1 THR B 103      12.573  43.782  23.391  1.00 95.66           O
ATOM   1731  CG2 THR B 103      15.098  43.633  23.162  1.00 89.27           C
ATOM   1732  C   THR B 103      14.331  43.532  20.407  1.00 89.61           C
ATOM   1733  O   THR B 103      14.076  44.667  20.108  1.00 89.87           O
ATOM   1734  N   GLN B 104      15.401  42.909  19.964  1.00 91.41           N
ATOM   1735  CA  GLN B 104      16.438  43.596  19.239  1.00 98.70           C
ATOM   1736  CB  GLN B 104      17.783  42.920  19.482  1.00105.19           C
ATOM   1737  CG  GLN B 104      18.276  43.126  20.876  1.00115.46           C
ATOM   1738  CD  GLN B 104      18.586  44.584  21.138  1.00120.28           C
ATOM   1739  OE1 GLN B 104      19.489  45.136  20.506  1.00124.47           O
ATOM   1740  NE2 GLN B 104      17.845  45.217  22.066  1.00120.01           N
ATOM   1741  C   GLN B 104      16.187  43.515  17.778  1.00101.03           C
ATOM   1742  O   GLN B 104      16.820  44.225  16.998  1.00105.92           O
ATOM   1743  N   VAL B 105      15.299  42.615  17.384  1.00100.83           N
ATOM   1744  CA  VAL B 105      15.225  42.234  15.970  1.00 99.37           C
ATOM   1745  CB  VAL B 105      16.429  41.279  15.526  1.00 95.68           C
ATOM   1746  CG1 VAL B 105      16.511  39.990  16.344  1.00 86.27           C
ATOM   1747  CG2 VAL B 105      16.424  41.027  14.022  1.00 97.97           C
ATOM   1748  C   VAL B 105      13.855  41.697  15.657  1.00 99.63           C
ATOM   1749  O   VAL B 105      13.325  40.841  16.383  1.00100.36           O
ATOM   1750  N   LYS B 106      13.282  42.205  14.577  1.00101.68           N
ATOM   1751  CA  LYS B 106      11.880  41.947  14.296  1.00107.71           C
ATOM   1752  CB  LYS B 106      11.513  42.530  12.936  1.00113.98           C
ATOM   1753  CG  LYS B 106      10.188  43.273  12.939  1.00120.73           C
ATOM   1754  CD  LYS B 106       9.027  42.332  12.642  1.00125.39           C
ATOM   1755  CE  LYS B 106       7.818  43.132  12.190  1.00130.09           C
ATOM   1756  NZ  LYS B 106       7.163  42.376  11.067  1.00136.35           N
ATOM   1757  C   LYS B 106      11.482  40.451  14.419  1.00107.56           C
ATOM   1758  O   LYS B 106      10.514  40.112  15.096  1.00105.74           O
ATOM   1759  N   ASN B 107      12.252  39.567  13.785  1.00107.30           N
ATOM   1760  CA  ASN B 107      12.052  38.137  13.895  1.00100.49           C
ATOM   1761  CB  ASN B 107      11.333  37.667  12.642  1.00102.07           C
ATOM   1762  CG  ASN B 107      11.053  36.167  12.636  1.00109.55           C
ATOM   1763  OD1 ASN B 107      11.853  35.321  13.117  1.00110.81           O
ATOM   1764  ND2 ASN B 107       9.907  35.817  12.051  1.00111.77           N
ATOM   1765  C   ASN B 107      13.409  37.462  14.007  1.00 97.43           C
ATOM   1766  O   ASN B 107      14.160  37.465  13.039  1.00 96.94           O
ATOM   1767  N   TYR B 108      13.758  36.888  15.158  1.00 96.00           N
ATOM   1768  CA  TYR B 108      15.127  36.279  15.258  1.00 97.48           C
ATOM   1769  CB  TYR B 108      15.538  35.907  16.714  1.00 95.32           C
ATOM   1770  CG  TYR B 108      14.988  34.598  17.237  1.00 91.28           C
ATOM   1771  CD1 TYR B 108      13.623  34.487  17.603  1.00 90.42           C
ATOM   1772  CE1 TYR B 108      13.096  33.280  18.099  1.00 91.36           C
ATOM   1773  CZ  TYR B 108      13.957  32.172  18.205  1.00 93.98           C
ATOM   1774  OH  TYR B 108      13.461  30.964  18.671  1.00 93.96           O
ATOM   1775  CE2 TYR B 108      15.327  32.278  17.836  1.00 90.30           C
ATOM   1776  CD2 TYR B 108      15.820  33.482  17.362  1.00 87.41           C
ATOM   1777  C   TYR B 108      15.432  35.114  14.297  1.00 97.15           C
ATOM   1778  O   TYR B 108      16.601  34.845  14.015  1.00 95.33           O
ATOM   1779  N   ILE B 109      14.391  34.425  13.817  1.00 97.90           N
ATOM   1780  CA  ILE B 109      14.593  33.286  12.931  1.00 96.08           C
ATOM   1781  CB  ILE B 109      13.387  32.318  12.888  1.00 94.62           C
ATOM   1782  CG1 ILE B 109      13.043  31.778  14.281  1.00 93.78           C
ATOM   1783  CD1 ILE B 109      13.893  30.536  14.740  1.00 89.31           C
ATOM   1784  CG2 ILE B 109      13.718  31.115  11.954  1.00 97.74           C
ATOM   1785  C   ILE B 109      14.915  33.774  11.526  1.00 95.31           C
ATOM   1786  O   ILE B 109      15.968  33.445  10.973  1.00 90.32           O
ATOM   1787  N   MET B 110      14.006  34.562  10.962  1.00 97.07           N
ATOM   1788  CA  MET B 110      14.193  35.087   9.629  1.00106.60           C
ATOM   1789  CB  MET B 110      13.097  36.090   9.267  1.00112.56           C
ATOM   1790  CG  MET B 110      11.690  35.471   9.419  1.00120.66           C
ATOM   1791  SD  MET B 110      10.411  35.780   8.136  1.00127.90           S
ATOM   1792  CE  MET B 110       8.982  34.729   8.658  1.00122.65           C
ATOM   1793  C   MET B 110      15.560  35.706   9.570  1.00101.89           C
ATOM   1794  O   MET B 110      16.326  35.472   8.638  1.00104.91           O
ATOM   1795  N   ALA B 111      15.903  36.431  10.619  1.00 98.33           N
ATOM   1796  CA  ALA B 111      17.163  37.145  10.647  1.00 92.69           C
ATOM   1797  CB  ALA B 111      17.153  38.229  11.698  1.00 92.31           C
ATOM   1798  C   ALA B 111      18.395  36.259  10.769  1.00 90.03           C
ATOM   1799  O   ALA B 111      19.419  36.623  10.221  1.00 95.85           O
ATOM   1800  N   THR B 112      18.314  35.119  11.454  1.00 84.35           N
ATOM   1801  CA  THR B 112      19.443  34.178  11.507  1.00 80.59           C
ATOM   1802  CB  THR B 112      19.283  33.215  12.673  1.00 79.08           C
ATOM   1803  OG1 THR B 112      18.876  33.952  13.825  1.00 78.79           O
ATOM   1804  CG2 THR B 112      20.575  32.363  12.956  1.00 73.40           C
ATOM   1805  C   THR B 112      19.545  33.373  10.206  1.00 84.10           C
ATOM   1806  O   THR B 112      20.640  33.045   9.742  1.00 83.67           O
ATOM   1807  N   SER B 113      18.391  33.052   9.631  1.00 86.12           N
ATOM   1808  CA  SER B 113      18.335  32.411   8.353  1.00 89.36           C
ATOM   1809  CB  SER B 113      16.891  32.075   8.023  1.00 96.52           C
ATOM   1810  OG  SER B 113      16.788  31.336   6.811  1.00103.11           O
ATOM   1811  C   SER B 113      18.975  33.321   7.289  1.00 91.33           C
ATOM   1812  O   SER B 113      19.916  32.875   6.626  1.00 93.34           O
ATOM   1813  N   GLN B 114      18.524  34.583   7.157  1.00 89.81           N
ATOM   1814  CA  GLN B 114      19.197  35.557   6.259  1.00 94.99           C
ATOM   1815  CB  GLN B 114      18.586  36.963   6.347  1.00100.43           C
ATOM   1816  CG  GLN B 114      17.504  37.259   5.285  1.00112.11           C
ATOM   1817  CD  GLN B 114      16.204  37.916   5.890  1.00122.14           C
ATOM   1818  OE1 GLN B 114      15.879  39.072   5.585  1.00126.37           O
ATOM   1819  NE2 GLN B 114      15.474  37.172   6.745  1.00123.99           N
ATOM   1820  C   GLN B 114      20.758  35.610   6.381  1.00 95.86           C
ATOM   1821  O   GLN B 114      21.476  35.316   5.417  1.00 94.02           O
ATOM   1822  N   ILE B 115      21.302  35.958   7.539  1.00 92.48           N
ATOM   1823  CA  ILE B 115      22.738  36.113   7.577  1.00 95.65           C
ATOM   1824  CB  ILE B 115      23.287  36.843   8.841  1.00100.69           C
ATOM   1825  CG1 ILE B 115      23.435  35.867   9.991  1.00105.20           C
ATOM   1826  CD1 ILE B 115      22.093  35.564  10.685  1.00107.60           C
ATOM   1827  CG2 ILE B 115      22.377  38.024   9.271  1.00103.76           C
ATOM   1828  C   ILE B 115      23.418  34.777   7.437  1.00 94.60           C
ATOM   1829  O   ILE B 115      24.639  34.738   7.171  1.00 95.69           O
ATOM   1830  N   SER B 116      22.652  33.692   7.624  1.00 90.69           N
ATOM   1831  CA  SER B 116      23.194  32.336   7.426  1.00 88.96           C
ATOM   1832  CB  SER B 116      22.326  31.309   8.082  1.00 86.04           C
ATOM   1833  OG  SER B 116      22.631  31.302   9.458  1.00 90.32           O
ATOM   1834  C   SER B 116      23.359  32.030   5.937  1.00 91.34           C
ATOM   1835  O   SER B 116      24.396  31.455   5.479  1.00 87.87           O
ATOM   1836  N   GLN B 117      22.355  32.464   5.174  1.00 87.55           N
ATOM   1837  CA  GLN B 117      22.464  32.441   3.737  1.00 85.07           C
ATOM   1838  CB  GLN B 117      21.186  32.918   3.109  1.00 87.06           C
ATOM   1839  CG  GLN B 117      19.973  32.541   3.905  1.00 89.91           C
ATOM   1840  CD  GLN B 117      18.802  32.309   3.015  1.00 92.38           C
ATOM   1841  OE1 GLN B 117      18.934  31.594   2.030  1.00 98.59           O
ATOM   1842  NE2 GLN B 117      17.647  32.897   3.339  1.00 87.77           N
ATOM   1843  C   GLN B 117      23.688  33.237   3.285  1.00 84.71           C
ATOM   1844  O   GLN B 117      24.691  32.623   2.944  1.00 86.94           O
ATOM   1845  N   THR B 118      23.616  34.575   3.320  1.00 85.90           N
ATOM   1846  CA  THR B 118      24.773  35.496   3.096  1.00 86.40           C
ATOM   1847  CB  THR B 118      24.612  36.798   3.852  1.00 83.97           C
ATOM   1848  OG1 THR B 118      23.696  37.596   3.132  1.00 87.07           O
ATOM   1849  CG2 THR B 118      25.932  37.540   3.968  1.00 82.86           C
ATOM   1850  C   THR B 118      26.150  34.963   3.473  1.00 87.38           C
ATOM   1851  O   THR B 118      27.095  35.022   2.660  1.00 90.46           O
ATOM   1852  N   THR B 119      26.286  34.441   4.683  1.00 83.64           N
ATOM   1853  CA  THR B 119      27.584  33.927   5.034  1.00 88.42           C
ATOM   1854  CB  THR B 119      27.673  33.623   6.452  1.00 91.51           C
ATOM   1855  OG1 THR B 119      27.265  34.784   7.185  1.00 97.28           O
ATOM   1856  CG2 THR B 119      29.113  33.182   6.776  1.00 88.40           C
ATOM   1857  C   THR B 119      27.927  32.652   4.311  1.00 90.77           C
ATOM   1858  O   THR B 119      29.079  32.482   3.919  1.00 89.21           O
ATOM   1859  N   LEU B 120      26.939  31.754   4.159  1.00 91.86           N
ATOM   1860  CA  LEU B 120      27.150  30.522   3.381  1.00 91.99           C
ATOM   1861  CB  LEU B 120      25.920  29.580   3.367  1.00 89.91           C
ATOM   1862  CG  LEU B 120      26.163  28.224   2.655  1.00 86.83           C
ATOM   1863  CD1 LEU B 120      27.409  27.483   3.180  1.00 84.66           C
ATOM   1864  CD2 LEU B 120      24.974  27.332   2.741  1.00 83.82           C
ATOM   1865  C   LEU B 120      27.576  30.855   1.956  1.00 95.08           C
ATOM   1866  O   LEU B 120      28.469  30.181   1.405  1.00 93.57           O
ATOM   1867  N   ARG B 121      26.935  31.885   1.385  1.00 96.51           N
ATOM   1868  CA  ARG B 121      27.161  32.251   0.018  1.00104.51           C
ATOM   1869  CB  ARG B 121      26.265  33.414  -0.385  1.00108.04           C
ATOM   1870  CG  ARG B 121      26.124  33.616  -1.930  1.00119.14           C
ATOM   1871  CD  ARG B 121      24.862  34.419  -2.357  1.00121.51           C
ATOM   1872  NE  ARG B 121      23.786  34.266  -1.356  1.00135.59           N
ATOM   1873  CZ  ARG B 121      22.751  35.103  -1.159  1.00140.73           C
ATOM   1874  NH1 ARG B 121      22.579  36.196  -1.912  1.00144.44           N
ATOM   1875  NH2 ARG B 121      21.862  34.838  -0.198  1.00140.74           N
ATOM   1876  C   ARG B 121      28.626  32.613  -0.088  1.00103.40           C
ATOM   1877  O   ARG B 121      29.361  32.060  -0.930  1.00103.30           O
ATOM   1878  N   SER B 122      29.063  33.489   0.817  1.00100.51           N
ATOM   1879  CA  SER B 122      30.412  34.038   0.755  1.00 97.55           C
ATOM   1880  CB  SER B 122      30.550  35.157   1.742  1.00 97.12           C
ATOM   1881  OG  SER B 122      29.689  36.162   1.288  1.00108.06           O
ATOM   1882  C   SER B 122      31.500  33.028   0.979  1.00 94.89           C
ATOM   1883  O   SER B 122      32.408  32.905   0.180  1.00 98.20           O
ATOM   1884  N   VAL B 123      31.411  32.312   2.078  1.00 91.74           N
ATOM   1885  CA  VAL B 123      32.340  31.254   2.373  1.00 90.55           C
ATOM   1886  CB  VAL B 123      31.811  30.449   3.533  1.00 87.73           C
ATOM   1887  CG1 VAL B 123      32.676  29.221   3.773  1.00 89.55           C
ATOM   1888  CG2 VAL B 123      31.742  31.305   4.752  1.00 86.27           C
ATOM   1889  C   VAL B 123      32.575  30.296   1.194  1.00 95.05           C
ATOM   1890  O   VAL B 123      33.690  29.767   1.033  1.00 92.83           O
ATOM   1891  N   ILE B 124      31.528  30.060   0.395  1.00 98.84           N
ATOM   1892  CA  ILE B 124      31.634  29.176  -0.765  1.00101.10           C
ATOM   1893  CB  ILE B 124      30.264  28.709  -1.279  1.00 97.59           C
ATOM   1894  CG1 ILE B 124      29.765  27.590  -0.388  1.00 94.24           C
ATOM   1895  CD1 ILE B 124      28.339  27.678  -0.203  1.00 93.02           C
ATOM   1896  CG2 ILE B 124      30.378  28.151  -2.673  1.00 96.30           C
ATOM   1897  C   ILE B 124      32.475  29.824  -1.860  1.00104.07           C
ATOM   1898  O   ILE B 124      33.547  29.308  -2.210  1.00104.14           O
ATOM   1899  N   GLY B 125      31.999  30.964  -2.367  1.00107.58           N
ATOM   1900  CA  GLY B 125      32.749  31.781  -3.329  1.00109.02           C
ATOM   1901  C   GLY B 125      34.237  31.858  -3.025  1.00109.82           C
ATOM   1902  O   GLY B 125      35.051  31.953  -3.930  1.00113.13           O
ATOM   1903  N   GLN B 126      34.587  31.793  -1.746  1.00111.22           N
ATOM   1904  CA  GLN B 126      35.976  31.880  -1.298  1.00112.41           C
ATOM   1905  CB  GLN B 126      36.052  32.567   0.084  1.00118.77           C
ATOM   1906  CG  GLN B 126      36.093  34.097   0.022  1.00126.21           C
ATOM   1907  CD  GLN B 126      37.252  34.576  -0.857  1.00131.75           C
ATOM   1908  OE1 GLN B 126      38.361  34.032  -0.780  1.00134.60           O
ATOM   1909  NE2 GLN B 126      36.993  35.567  -1.718  1.00132.17           N
ATOM   1910  C   GLN B 126      36.687  30.532  -1.245  1.00108.69           C
ATOM   1911  O   GLN B 126      37.868  30.484  -0.870  1.00105.84           O
ATOM   1912  N   ALA B 127      35.976  29.452  -1.615  1.00105.11           N
ATOM   1913  CA  ALA B 127      36.458  28.069  -1.401  1.00 98.79           C
ATOM   1914  CB  ALA B 127      35.568  27.317  -0.487  1.00 94.86           C
ATOM   1915  C   ALA B 127      36.579  27.332  -2.682  1.00 96.99           C
ATOM   1916  O   ALA B 127      35.903  27.643  -3.657  1.00 97.76           O
ATOM   1917  N   HIS B 128      37.473  26.358  -2.668  1.00 98.10           N
ATOM   1918  CA  HIS B 128      37.829  25.631  -3.853  1.00101.28           C
ATOM   1919  CB  HIS B 128      39.343  25.232  -3.839  1.00113.66           C
ATOM   1920  CG  HIS B 128      40.294  26.359  -4.178  1.00124.89           C
ATOM   1921  ND1 HIS B 128      40.758  26.590  -5.460  1.00127.37           N
ATOM   1922  CE1 HIS B 128      41.553  27.649  -5.463  1.00128.44           C
ATOM   1923  NE2 HIS B 128      41.622  28.119  -4.230  1.00130.10           N
ATOM   1924  CD2 HIS B 128      40.853  27.327  -3.404  1.00128.39           C
ATOM   1925  C   HIS B 128      36.952  24.415  -3.769  1.00 97.95           C
ATOM   1926  O   HIS B 128      36.925  23.748  -2.730  1.00 91.93           O
ATOM   1927  N   LEU B 129      36.227  24.116  -4.844  1.00 96.14           N
ATOM   1928  CA  LEU B 129      35.526  22.826  -4.922  1.00 94.89           C
ATOM   1929  CB  LEU B 129      35.500  22.243  -6.326  1.00 91.28           C
ATOM   1930  CG  LEU B 129      34.594  21.015  -6.354  1.00 86.28           C
ATOM   1931  CD1 LEU B 129      33.243  21.470  -5.849  1.00 84.66           C
ATOM   1932  CD2 LEU B 129      34.493  20.419  -7.745  1.00 83.82           C
ATOM   1933  C   LEU B 129      36.101  21.754  -4.023  1.00 96.40           C
ATOM   1934  O   LEU B 129      35.403  21.240  -3.186  1.00103.63           O
ATOM   1935  N   ASP B 130      37.354  21.385  -4.194  1.00 97.37           N
ATOM   1936  CA  ASP B 130      37.869  20.340  -3.345  1.00 99.30           C
ATOM   1937  CB  ASP B 130      39.284  19.944  -3.733  1.00106.84           C
ATOM   1938  CG  ASP B 130      39.547  18.491  -3.430  1.00111.24           C
ATOM   1939  OD1 ASP B 130      40.160  18.191  -2.377  1.00110.10           O
ATOM   1940  OD2 ASP B 130      39.059  17.653  -4.221  1.00113.50           O
ATOM   1941  C   ASP B 130      37.807  20.607  -1.835  1.00 96.23           C
ATOM   1942  O   ASP B 130      37.876  19.655  -1.046  1.00 93.41           O
ATOM   1943  N   GLU B 131      37.690  21.877  -1.424  1.00 93.32           N
ATOM   1944  CA  GLU B 131      37.587  22.196   0.016  1.00 94.14           C
ATOM   1945  CB  GLU B 131      37.815  23.663   0.310  1.00 96.88           C
ATOM   1946  CG  GLU B 131      39.253  24.102   0.499  1.00104.68           C
ATOM   1947  CD  GLU B 131      39.355  25.625   0.408  1.00110.88           C
ATOM   1948  OE1 GLU B 131      39.292  26.175  -0.730  1.00110.32           O
ATOM   1949  OE2 GLU B 131      39.457  26.277   1.486  1.00115.35           O
ATOM   1950  C   GLU B 131      36.202  21.848   0.453  1.00 93.20           C
ATOM   1951  O   GLU B 131      36.020  21.225   1.474  1.00 95.62           O
ATOM   1952  N   LEU B 132      35.239  22.272  -0.360  1.00 91.30           N
ATOM   1953  CA  LEU B 132      33.844  21.957  -0.234  1.00 87.63           C
ATOM   1954  CB  LEU B 132      33.125  22.349  -1.491  1.00 89.88           C
ATOM   1955  CG  LEU B 132      32.181  23.536  -1.497  1.00 98.01           C
ATOM   1956  CD1 LEU B 132      30.894  23.115  -2.239  1.00 98.95           C
ATOM   1957  CD2 LEU B 132      31.843  23.984  -0.102  1.00101.13           C
ATOM   1958  C   LEU B 132      33.565  20.503  -0.048  1.00 89.85           C
ATOM   1959  O   LEU B 132      32.660  20.160   0.695  1.00 96.31           O
ATOM   1960  N   LEU B 133      34.290  19.631  -0.733  1.00 88.35           N
ATOM   1961  CA  LEU B 133      33.981  18.195  -0.639  1.00 89.93           C
ATOM   1962  CB  LEU B 133      33.984  17.490  -2.025  1.00 86.55           C
ATOM   1963  CG  LEU B 133      33.766  18.218  -3.354  1.00 82.58           C
ATOM   1964  CD1 LEU B 133      34.643  17.580  -4.328  1.00 87.95           C
ATOM   1965  CD2 LEU B 133      32.417  18.130  -3.853  1.00 78.10           C
ATOM   1966  C   LEU B 133      34.919  17.451   0.314  1.00 91.47           C
ATOM   1967  O   LEU B 133      34.675  16.263   0.647  1.00 92.59           O
ATOM   1968  N   SER B 134      35.992  18.133   0.728  1.00 91.76           N
ATOM   1969  CA  SER B 134      37.134  17.419   1.283  1.00 94.27           C
ATOM   1970  CB  SER B 134      38.243  17.275   0.261  1.00 88.12           C
ATOM   1971  OG  SER B 134      37.993  16.122  -0.484  1.00 85.26           O
ATOM   1972  C   SER B 134      37.721  17.980   2.519  1.00100.14           C
ATOM   1973  O   SER B 134      38.465  17.274   3.188  1.00104.10           O
ATOM   1974  N   GLU B 135      37.456  19.257   2.777  1.00104.54           N
ATOM   1975  CA  GLU B 135      37.868  19.927   4.005  1.00107.65           C
ATOM   1976  CB  GLU B 135      38.972  20.921   3.715  1.00112.24           C
ATOM   1977  CG  GLU B 135      40.309  20.351   3.259  1.00118.22           C
ATOM   1978  CD  GLU B 135      41.152  21.421   2.602  1.00121.55           C
ATOM   1979  OE1 GLU B 135      41.450  22.457   3.265  1.00122.29           O
ATOM   1980  OE2 GLU B 135      41.470  21.235   1.406  1.00122.90           O
ATOM   1981  C   GLU B 135      36.641  20.671   4.484  1.00109.40           C
ATOM   1982  O   GLU B 135      36.630  21.909   4.613  1.00105.43           O
ATOM   1983  N   ARG B 136      35.574  19.909   4.693  1.00111.51           N
ATOM   1984  CA  ARG B 136      34.292  20.512   4.992  1.00112.55           C
ATOM   1985  CB  ARG B 136      33.231  19.445   4.991  1.00117.76           C
ATOM   1986  CG  ARG B 136      32.297  19.504   3.852  1.00123.47           C
ATOM   1987  CD  ARG B 136      30.916  19.183   4.478  1.00133.15           C
ATOM   1988  NE  ARG B 136      30.027  18.580   3.489  1.00139.30           N
ATOM   1989  CZ  ARG B 136      29.706  17.264   3.448  1.00140.62           C
ATOM   1990  NH1 ARG B 136      30.193  16.373   4.361  1.00140.61           N
ATOM   1991  NH2 ARG B 136      28.882  16.863   2.476  1.00140.86           N
ATOM   1992  C   ARG B 136      34.388  21.113   6.370  1.00110.53           C
ATOM   1993  O   ARG B 136      33.941  22.225   6.638  1.00108.90           O
ATOM   1994  N   ASP B 137      35.004  20.343   7.242  1.00108.81           N
ATOM   1995  CA  ASP B 137      35.206  20.743   8.580  1.00107.57           C
ATOM   1996  CB  ASP B 137      36.233  19.821   9.165  1.00110.25           C
ATOM   1997  CG  ASP B 137      36.013  19.579  10.606  1.00112.65           C
ATOM   1998  OD1 ASP B 137      35.895  20.540  11.406  1.00110.84           O
ATOM   1999  OD2 ASP B 137      35.985  18.387  10.934  1.00117.81           O
ATOM   2000  C   ASP B 137      35.703  22.185   8.634  1.00108.77           C
ATOM   2001  O   ASP B 137      35.119  23.004   9.352  1.00111.62           O
ATOM   2002  N   LYS B 138      36.763  22.505   7.880  1.00104.80           N
ATOM   2003  CA  LYS B 138      37.384  23.821   7.991  1.00102.78           C
ATOM   2004  CB  LYS B 138      38.628  24.021   7.074  1.00113.31           C
ATOM   2005  CG  LYS B 138      39.904  23.157   7.399  1.00119.65           C
ATOM   2006  CD  LYS B 138      39.665  21.587   7.185  1.00123.16           C
ATOM   2007  CE  LYS B 138      40.961  20.695   7.229  1.00121.67           C
ATOM   2008  NZ  LYS B 138      41.770  20.461   5.951  1.00118.26           N
ATOM   2009  C   LYS B 138      36.294  24.821   7.699  1.00 99.01           C
ATOM   2010  O   LYS B 138      36.025  25.689   8.531  1.00 97.79           O
ATOM   2011  N   LEU B 139      35.628  24.669   6.549  1.00 95.51           N
ATOM   2012  CA  LEU B 139      34.551  25.600   6.144  1.00 90.73           C
ATOM   2013  CB  LEU B 139      34.031  25.261   4.743  1.00 84.64           C
ATOM   2014  CG  LEU B 139      35.289  25.236   3.912  1.00 82.42           C
ATOM   2015  CD1 LEU B 139      35.274  24.270   2.801  1.00 85.33           C
ATOM   2016  CD2 LEU B 139      35.297  26.555   3.364  1.00 89.72           C
ATOM   2017  C   LEU B 139      33.428  25.652   7.194  1.00 90.24           C
ATOM   2018  O   LEU B 139      32.911  26.718   7.525  1.00 88.39           O
ATOM   2019  N   ASN B 140      33.079  24.492   7.731  1.00 90.10           N
ATOM   2020  CA  ASN B 140      32.107  24.414   8.789  1.00 93.80           C
ATOM   2021  CB  ASN B 140      31.989  22.977   9.258  1.00 93.66           C
ATOM   2022  CG  ASN B 140      30.948  22.237   8.514  1.00 94.30           C
ATOM   2023  OD1 ASN B 140      30.118  22.851   7.844  1.00 97.38           O
ATOM   2024  ND2 ASN B 140      30.960  20.917   8.613  1.00 94.19           N
ATOM   2025  C   ASN B 140      32.427  25.327   9.962  1.00 99.48           C
ATOM   2026  O   ASN B 140      31.618  26.225  10.293  1.00100.68           O
ATOM   2027  N   MET B 141      33.594  25.100  10.587  1.00102.48           N
ATOM   2028  CA  MET B 141      34.077  25.980  11.662  1.00107.67           C
ATOM   2029  CB  MET B 141      35.425  25.534  12.207  1.00111.41           C
ATOM   2030  CG  MET B 141      35.284  24.841  13.529  1.00116.35           C
ATOM   2031  SD  MET B 141      36.336  23.369  13.655  1.00126.32           S
ATOM   2032  CE  MET B 141      36.042  22.786  15.368  1.00119.98           C
ATOM   2033  C   MET B 141      34.091  27.435  11.232  1.00100.64           C
ATOM   2034  O   MET B 141      33.460  28.244  11.870  1.00 96.96           O
ATOM   2035  N   GLN B 142      34.754  27.758  10.127  1.00 97.62           N
ATOM   2036  CA  GLN B 142      34.683  29.101   9.585  1.00 98.24           C
ATOM   2037  CB  GLN B 142      35.011  29.102   8.106  1.00106.21           C
ATOM   2038  CG  GLN B 142      36.228  29.945   7.747  1.00116.45           C
ATOM   2039  CD  GLN B 142      36.437  30.020   6.245  1.00119.51           C
ATOM   2040  OE1 GLN B 142      36.115  31.048   5.621  1.00120.70           O
ATOM   2041  NE2 GLN B 142      36.958  28.921   5.645  1.00116.72           N
ATOM   2042  C   GLN B 142      33.338  29.759   9.759  1.00 94.24           C
ATOM   2043  O   GLN B 142      33.256  30.861  10.270  1.00 96.02           O
ATOM   2044  N   LEU B 143      32.292  29.057   9.328  1.00 93.08           N
ATOM   2045  CA  LEU B 143      30.897  29.523   9.293  1.00 85.76           C
ATOM   2046  CB  LEU B 143      30.083  28.457   8.592  1.00 82.94           C
ATOM   2047  CG  LEU B 143      30.156  28.243   7.096  1.00 80.08           C
ATOM   2048  CD1 LEU B 143      29.752  26.798   6.848  1.00 78.68           C
ATOM   2049  CD2 LEU B 143      29.208  29.231   6.398  1.00 77.99           C
ATOM   2050  C   LEU B 143      30.292  29.722  10.683  1.00 86.96           C
ATOM   2051  O   LEU B 143      29.508  30.670  10.919  1.00 82.14           O
ATOM   2052  N   GLN B 144      30.637  28.778  11.571  1.00 86.49           N
ATOM   2053  CA  GLN B 144      30.247  28.779  12.973  1.00 87.57           C
ATOM   2054  CB  GLN B 144      30.923  27.583  13.653  1.00 92.68           C
ATOM   2055  CG  GLN B 144      30.556  27.310  15.134  1.00 96.77           C
ATOM   2056  CD  GLN B 144      30.897  28.457  16.062  1.00 96.79           C
ATOM   2057  OE1 GLN B 144      32.046  28.897  16.131  1.00 99.17           O
ATOM   2058  NE2 GLN B 144      29.900  28.954  16.770  1.00 94.57           N
ATOM   2059  C   GLN B 144      30.639  30.100  13.645  1.00 87.66           C
ATOM   2060  O   GLN B 144      29.787  30.812  14.155  1.00 89.33           O
ATOM   2061  N   ARG B 145      31.948  30.365  13.660  1.00 92.28           N
ATOM   2062  CA  ARG B 145      32.630  31.624  14.027  1.00 94.81           C
ATOM   2063  CB  ARG B 145      34.080  31.519  13.505  1.00105.15           C
ATOM   2064  CG  ARG B 145      35.113  32.364  14.198  1.00119.70           C
ATOM   2065  CD  ARG B 145      36.105  33.041  13.189  1.00130.92           C
ATOM   2066  NE  ARG B 145      36.454  34.427  13.595  1.00138.28           N
ATOM   2067  CZ  ARG B 145      37.230  34.750  14.648  1.00142.20           C
ATOM   2068  NH1 ARG B 145      37.765  33.809  15.433  1.00143.14           N
ATOM   2069  NH2 ARG B 145      37.476  36.025  14.936  1.00143.49           N
ATOM   2070  C   ARG B 145      31.930  32.926  13.499  1.00 90.71           C
ATOM   2071  O   ARG B 145      31.539  33.806  14.282  1.00 88.66           O
ATOM   2072  N   ILE B 146      31.745  33.046  12.188  1.00 83.56           N
ATOM   2073  CA  ILE B 146      31.154  34.264  11.641  1.00 85.70           C
ATOM   2074  CB  ILE B 146      31.123  34.223  10.098  1.00 83.97           C
ATOM   2075  CG1 ILE B 146      32.528  34.085   9.548  1.00 79.41           C
ATOM   2076  CD1 ILE B 146      32.602  33.073   8.458  1.00 83.01           C
ATOM   2077  CG2 ILE B 146      30.354  35.473   9.518  1.00 84.62           C
ATOM   2078  C   ILE B 146      29.720  34.480  12.100  1.00 89.87           C
ATOM   2079  O   ILE B 146      29.227  35.635  12.320  1.00 85.52           O
ATOM   2080  N   ILE B 147      29.037  33.339  12.145  1.00 96.48           N
ATOM   2081  CA  ILE B 147      27.610  33.347  12.290  1.00 97.97           C
ATOM   2082  CB  ILE B 147      26.871  32.124  11.656  1.00 97.68           C
ATOM   2083  CG1 ILE B 147      26.928  32.181  10.123  1.00 97.35           C
ATOM   2084  CD1 ILE B 147      26.321  30.957   9.412  1.00 97.46           C
ATOM   2085  CG2 ILE B 147      25.393  32.135  12.054  1.00 97.37           C
ATOM   2086  C   ILE B 147      27.352  33.515  13.753  1.00 97.76           C
ATOM   2087  O   ILE B 147      26.501  34.332  14.074  1.00 99.50           O
ATOM   2088  N   ASP B 148      28.103  32.835  14.637  1.00 94.50           N
ATOM   2089  CA  ASP B 148      27.724  32.905  16.046  1.00 98.16           C
ATOM   2090  CB  ASP B 148      28.584  32.114  17.013  1.00 95.20           C
ATOM   2091  CG  ASP B 148      28.000  32.173  18.453  1.00100.40           C
ATOM   2092  OD1 ASP B 148      26.848  32.733  18.694  1.00 95.83           O
ATOM   2093  OD2 ASP B 148      28.711  31.662  19.342  1.00103.77           O
ATOM   2094  C   ASP B 148      27.696  34.340  16.515  1.00101.86           C
ATOM   2095  O   ASP B 148      26.696  34.773  17.240  1.00 96.55           O
ATOM   2096  N   GLU B 149      28.818  34.992  16.102  1.00 99.93           N
ATOM   2097  CA  GLU B 149      29.139  36.425  16.148  1.00 97.48           C
ATOM   2098  CB  GLU B 149      30.341  36.707  15.253  1.00106.21           C
ATOM   2099  CG  GLU B 149      30.591  38.193  14.930  1.00116.36           C
ATOM   2100  CD  GLU B 149      31.565  38.875  15.921  1.00123.54           C
ATOM   2101  OE1 GLU B 149      32.058  38.183  16.856  1.00124.35           O
ATOM   2102  OE2 GLU B 149      31.836  40.105  15.761  1.00126.35           O
ATOM   2103  C   GLU B 149      27.974  37.267  15.701  1.00 92.45           C
ATOM   2104  O   GLU B 149      27.272  37.798  16.548  1.00 87.98           O
ATOM   2105  N   ALA B 150      27.734  37.367  14.391  1.00 92.32           N
ATOM   2106  CA  ALA B 150      26.522  38.075  13.883  1.00 96.27           C
ATOM   2107  CB  ALA B 150      26.133  37.548  12.539  1.00 94.15           C
ATOM   2108  C   ALA B 150      25.295  38.019  14.806  1.00 97.00           C
ATOM   2109  O   ALA B 150      24.555  38.977  14.920  1.00 96.54           O
ATOM   2110  N   THR B 151      25.142  36.875  15.466  1.00100.64           N
ATOM   2111  CA  THR B 151      23.966  36.432  16.181  1.00100.30           C
ATOM   2112  CB  THR B 151      24.034  34.922  16.339  1.00 98.97           C
ATOM   2113  OG1 THR B 151      24.530  34.368  15.133  1.00 94.39           O
ATOM   2114  CG2 THR B 151      22.675  34.381  16.518  1.00104.06           C
ATOM   2115  C   THR B 151      23.813  36.956  17.596  1.00102.15           C
ATOM   2116  O   THR B 151      22.704  36.849  18.153  1.00103.36           O
ATOM   2117  N   ASP B 152      24.902  37.474  18.189  1.00 99.78           N
ATOM   2118  CA  ASP B 152      24.889  37.878  19.614  1.00 95.01           C
ATOM   2119  CB  ASP B 152      26.286  37.979  20.224  1.00 95.44           C
ATOM   2120  CG  ASP B 152      27.147  36.718  19.986  1.00103.42           C
ATOM   2121  OD1 ASP B 152      26.593  35.653  19.553  1.00110.64           O
ATOM   2122  OD2 ASP B 152      28.392  36.793  20.224  1.00101.03           O
ATOM   2123  C   ASP B 152      24.054  39.120  19.874  1.00 94.02           C
ATOM   2124  O   ASP B 152      23.345  39.187  20.857  1.00 96.75           O
ATOM   2125  N   PRO B 153      24.104  40.114  18.994  1.00 95.23           N
ATOM   2126  CA  PRO B 153      23.087  41.162  19.097  1.00 98.60           C
ATOM   2127  CB  PRO B 153      23.075  41.766  17.691  1.00 99.97           C
ATOM   2128  CG  PRO B 153      24.513  41.631  17.243  1.00102.56           C
ATOM   2129  CD  PRO B 153      25.077  40.396  17.924  1.00 99.59           C
ATOM   2130  C   PRO B 153      21.676  40.687  19.446  1.00 99.99           C
ATOM   2131  O   PRO B 153      20.859  41.481  19.923  1.00102.50           O
ATOM   2132  N   TRP B 154      21.396  39.410  19.200  1.00103.50           N
ATOM   2133  CA  TRP B 154      20.027  38.860  19.277  1.00103.50           C
ATOM   2134  CB  TRP B 154      19.615  38.240  17.933  1.00105.75           C
ATOM   2135  CG  TRP B 154      19.809  39.123  16.698  1.00108.48           C
ATOM   2136  CD1 TRP B 154      19.614  40.470  16.608  1.00109.66           C
ATOM   2137  NE1 TRP B 154      19.846  40.902  15.312  1.00109.69           N
ATOM   2138  CE2 TRP B 154      20.193  39.832  14.544  1.00104.44           C
ATOM   2139  CD2 TRP B 154      20.182  38.691  15.374  1.00108.20           C
ATOM   2140  CE3 TRP B 154      20.500  37.448  14.814  1.00107.98           C
ATOM   2141  CZ3 TRP B 154      20.810  37.396  13.484  1.00107.03           C
ATOM   2142  CH2 TRP B 154      20.818  38.556  12.705  1.00106.15           C
ATOM   2143  CZ2 TRP B 154      20.510  39.776  13.226  1.00103.49           C
ATOM   2144  C   TRP B 154      19.822  37.837  20.406  1.00 99.01           C
ATOM   2145  O   TRP B 154      18.716  37.384  20.638  1.00 98.62           O
ATOM   2146  N   GLY B 155      20.891  37.477  21.096  1.00 95.54           N
ATOM   2147  CA  GLY B 155      20.784  36.642  22.273  1.00 94.56           C
ATOM   2148  C   GLY B 155      20.976  35.185  21.955  1.00 94.72           C
ATOM   2149  O   GLY B 155      20.587  34.319  22.735  1.00 97.56           O
ATOM   2150  N   ILE B 156      21.584  34.907  20.810  1.00 90.97           N
ATOM   2151  CA  ILE B 156      21.629  33.547  20.348  1.00 86.33           C
ATOM   2152  CB  ILE B 156      20.964  33.415  18.972  1.00 81.93           C
ATOM   2153  CG1 ILE B 156      19.479  33.288  19.140  1.00 79.69           C
ATOM   2154  CD1 ILE B 156      18.774  34.472  18.949  1.00 82.17           C
ATOM   2155  CG2 ILE B 156      21.377  32.111  18.308  1.00 84.28           C
ATOM   2156  C   ILE B 156      23.040  32.991  20.316  1.00 87.34           C
ATOM   2157  O   ILE B 156      23.963  33.555  19.638  1.00 91.68           O
ATOM   2158  N   LYS B 157      23.212  31.878  21.024  1.00 84.39           N
ATOM   2159  CA  LYS B 157      24.428  31.099  20.842  1.00 88.19           C
ATOM   2160  CB  LYS B 157      24.882  30.362  22.109  1.00 90.13           C
ATOM   2161  CG  LYS B 157      26.334  29.873  21.936  1.00 99.75           C
ATOM   2162  CD  LYS B 157      27.012  29.552  23.243  1.00109.52           C
ATOM   2163  CE  LYS B 157      28.542  29.511  23.089  1.00115.40           C
ATOM   2164  NZ  LYS B 157      29.134  28.966  24.380  1.00121.19           N
ATOM   2165  C   LYS B 157      24.314  30.104  19.684  1.00 89.33           C
ATOM   2166  O   LYS B 157      23.542  29.135  19.778  1.00 92.74           O
ATOM   2167  N   VAL B 158      25.114  30.316  18.632  1.00 81.26           N
ATOM   2168  CA  VAL B 158      25.215  29.359  17.566  1.00 75.93           C
ATOM   2169  CB  VAL B 158      25.511  30.069  16.285  1.00 73.94           C
ATOM   2170  CG1 VAL B 158      25.880  29.074  15.199  1.00 78.23           C
ATOM   2171  CG2 VAL B 158      24.350  30.918  15.871  1.00 73.09           C
ATOM   2172  C   VAL B 158      26.347  28.384  17.851  1.00 79.31           C
ATOM   2173  O   VAL B 158      27.479  28.746  17.779  1.00 83.66           O
ATOM   2174  N   THR B 159      26.043  27.131  18.138  1.00 85.97           N
ATOM   2175  CA  THR B 159      27.056  26.100  18.435  1.00 91.59           C
ATOM   2176  CB  THR B 159      26.429  25.002  19.270  1.00 96.43           C
ATOM   2177  OG1 THR B 159      25.608  25.631  20.257  1.00103.07           O
ATOM   2178  CG2 THR B 159      27.514  24.169  19.982  1.00101.07           C
ATOM   2179  C   THR B 159      27.774  25.426  17.242  1.00 91.75           C
ATOM   2180  O   THR B 159      28.975  25.166  17.301  1.00 93.06           O
ATOM   2181  N   ALA B 160      27.050  25.072  16.188  1.00 88.57           N
ATOM   2182  CA  ALA B 160      27.709  24.573  14.980  1.00 83.11           C
ATOM   2183  CB  ALA B 160      27.784  23.087  14.981  1.00 77.21           C
ATOM   2184  C   ALA B 160      26.957  25.053  13.769  1.00 85.41           C
ATOM   2185  O   ALA B 160      25.772  25.414  13.872  1.00 90.07           O
ATOM   2186  N   VAL B 161      27.639  25.068  12.623  1.00 82.77           N
ATOM   2187  CA  VAL B 161      26.969  25.231  11.340  1.00 77.92           C
ATOM   2188  CB  VAL B 161      27.218  26.613  10.798  1.00 76.00           C
ATOM   2189  CG1 VAL B 161      27.038  26.649   9.298  1.00 75.60           C
ATOM   2190  CG2 VAL B 161      26.285  27.603  11.504  1.00 74.85           C
ATOM   2191  C   VAL B 161      27.598  24.160  10.512  1.00 78.75           C
ATOM   2192  O   VAL B 161      28.806  24.088  10.521  1.00 87.70           O
ATOM   2193  N   GLU B 162      26.816  23.261   9.908  1.00 80.09           N
ATOM   2194  CA  GLU B 162      27.368  22.135   9.093  1.00 83.75           C
ATOM   2195  CB  GLU B 162      27.160  20.775   9.745  1.00 82.29           C
ATOM   2196  CG  GLU B 162      27.760  20.698  11.136  1.00 89.98           C
ATOM   2197  CD  GLU B 162      27.477  19.389  11.905  1.00 92.81           C
ATOM   2198  OE1 GLU B 162      26.494  18.648  11.577  1.00 95.97           O
ATOM   2199  OE2 GLU B 162      28.253  19.141  12.872  1.00 94.72           O
ATOM   2200  C   GLU B 162      26.801  22.105   7.686  1.00 84.28           C
ATOM   2201  O   GLU B 162      25.583  22.201   7.469  1.00 88.76           O
ATOM   2202  N   ILE B 163      27.685  22.005   6.717  1.00 84.54           N
ATOM   2203  CA  ILE B 163      27.254  21.935   5.342  1.00 86.34           C
ATOM   2204  CB  ILE B 163      28.432  22.119   4.375  1.00 84.21           C
ATOM   2205  CG1 ILE B 163      28.936  23.556   4.422  1.00 82.72           C
ATOM   2206  CD1 ILE B 163      30.411  23.678   4.200  1.00 80.62           C
ATOM   2207  CG2 ILE B 163      28.010  21.817   2.989  1.00 83.76           C
ATOM   2208  C   ILE B 163      26.642  20.548   5.193  1.00 91.82           C
ATOM   2209  O   ILE B 163      27.273  19.527   5.564  1.00 95.80           O
ATOM   2210  N   LYS B 164      25.410  20.539   4.678  1.00 91.95           N
ATOM   2211  CA  LYS B 164      24.612  19.348   4.499  1.00 91.01           C
ATOM   2212  CB  LYS B 164      23.158  19.672   4.828  1.00 94.32           C
ATOM   2213  CG  LYS B 164      22.353  18.540   5.416  1.00 99.65           C
ATOM   2214  CD  LYS B 164      20.855  18.861   5.399  1.00105.75           C
ATOM   2215  CE  LYS B 164      20.034  17.597   5.107  1.00109.64           C
ATOM   2216  NZ  LYS B 164      18.729  17.937   4.434  1.00113.09           N
ATOM   2217  C   LYS B 164      24.803  18.794   3.068  1.00 91.18           C
ATOM   2218  O   LYS B 164      25.765  18.102   2.823  1.00 94.27           O
ATOM   2219  N   ASP B 165      23.926  19.086   2.117  1.00 92.88           N
ATOM   2220  CA  ASP B 165      24.026  18.473   0.771  1.00 93.52           C
ATOM   2221  CB  ASP B 165      22.626  18.135   0.209  1.00 94.92           C
ATOM   2222  CG  ASP B 165      21.981  16.945   0.911  1.00 98.85           C
ATOM   2223  OD1 ASP B 165      22.482  15.802   0.767  1.00100.89           O
ATOM   2224  OD2 ASP B 165      20.974  17.149   1.615  1.00100.13           O
ATOM   2225  C   ASP B 165      24.793  19.348  -0.223  1.00 93.75           C
ATOM   2226  O   ASP B 165      24.609  20.597  -0.250  1.00 96.49           O
ATOM   2227  N   VAL B 166      25.640  18.716  -1.047  1.00 89.34           N
ATOM   2228  CA  VAL B 166      26.341  19.489  -2.102  1.00 89.70           C
ATOM   2229  CB  VAL B 166      27.845  19.574  -1.897  1.00 87.67           C
ATOM   2230  CG1 VAL B 166      28.396  20.581  -2.856  1.00 86.11           C
ATOM   2231  CG2 VAL B 166      28.170  19.962  -0.488  1.00 88.63           C
ATOM   2232  C   VAL B 166      26.135  19.044  -3.555  1.00 89.29           C
ATOM   2233  O   VAL B 166      26.582  17.976  -3.949  1.00 94.77           O
ATOM   2234  N   GLU B 167      25.505  19.895  -4.351  1.00 85.61           N
ATOM   2235  CA  GLU B 167      25.254  19.611  -5.757  1.00 82.62           C
ATOM   2236  CB  GLU B 167      23.873  20.132  -6.108  1.00 82.26           C
ATOM   2237  CG  GLU B 167      22.828  19.772  -5.085  1.00 85.91           C
ATOM   2238  CD  GLU B 167      21.423  19.948  -5.620  1.00 90.85           C
ATOM   2239  OE1 GLU B 167      20.996  21.096  -5.857  1.00 96.21           O
ATOM   2240  OE2 GLU B 167      20.739  18.938  -5.845  1.00 94.68           O
ATOM   2241  C   GLU B 167      26.304  20.220  -6.728  1.00 79.34           C
ATOM   2242  O   GLU B 167      26.576  21.417  -6.645  1.00 82.68           O
ATOM   2243  N   LEU B 168      26.884  19.398  -7.615  1.00 71.61           N
ATOM   2244  CA  LEU B 168      27.695  19.856  -8.740  1.00 69.09           C
ATOM   2245  CB  LEU B 168      29.013  19.094  -8.822  1.00 68.32           C
ATOM   2246  CG  LEU B 168      29.768  18.781  -7.520  1.00 68.09           C
ATOM   2247  CD1 LEU B 168      30.732  17.605  -7.626  1.00 68.91           C
ATOM   2248  CD2 LEU B 168      30.517  19.914  -7.079  1.00 70.37           C
ATOM   2249  C   LEU B 168      26.893  19.613 -10.019  1.00 76.44           C
ATOM   2250  O   LEU B 168      25.891  18.877  -9.984  1.00 83.18           O
ATOM   2251  N   PRO B 169      27.285  20.250 -11.159  1.00 77.14           N
ATOM   2252  CA  PRO B 169      26.560  20.022 -12.415  1.00 75.22           C
ATOM   2253  CB  PRO B 169      27.402  20.795 -13.422  1.00 73.28           C
ATOM   2254  CG  PRO B 169      27.970  21.940 -12.607  1.00 69.62           C
ATOM   2255  CD  PRO B 169      28.365  21.240 -11.353  1.00 75.00           C
ATOM   2256  C   PRO B 169      26.511  18.563 -12.809  1.00 78.06           C
ATOM   2257  O   PRO B 169      27.506  17.829 -12.624  1.00 82.54           O
ATOM   2258  N   ALA B 170      25.362  18.139 -13.332  1.00 79.12           N
ATOM   2259  CA  ALA B 170      25.140  16.724 -13.697  1.00 79.40           C
ATOM   2260  CB  ALA B 170      23.822  16.566 -14.387  1.00 75.62           C
ATOM   2261  C   ALA B 170      26.265  16.070 -14.520  1.00 81.02           C
ATOM   2262  O   ALA B 170      26.524  16.453 -15.653  1.00 77.19           O
ATOM   2263  N   GLY B 171      26.938  15.092 -13.929  1.00 84.60           N
ATOM   2264  CA  GLY B 171      27.906  14.329 -14.682  1.00 87.94           C
ATOM   2265  C   GLY B 171      29.359  14.583 -14.345  1.00 91.69           C
ATOM   2266  O   GLY B 171      30.227  13.761 -14.705  1.00 91.20           O
ATOM   2267  N   MET B 172      29.620  15.704 -13.654  1.00 94.26           N
ATOM   2268  CA  MET B 172      30.992  16.224 -13.403  1.00 89.79           C
ATOM   2269  CB  MET B 172      30.956  17.684 -12.917  1.00 84.45           C
ATOM   2270  CG  MET B 172      32.242  18.161 -12.318  1.00 86.49           C
ATOM   2271  SD  MET B 172      32.423  19.866 -11.656  1.00 93.62           S
ATOM   2272  CE  MET B 172      31.570  20.832 -12.927  1.00 92.35           C
ATOM   2273  C   MET B 172      31.677  15.316 -12.386  1.00 92.22           C
ATOM   2274  O   MET B 172      32.843  14.948 -12.558  1.00 86.61           O
ATOM   2275  N   GLN B 173      30.938  14.916 -11.338  1.00 95.48           N
ATOM   2276  CA  GLN B 173      31.536  14.011 -10.346  1.00 89.70           C
ATOM   2277  CB  GLN B 173      30.702  13.878  -9.078  1.00 87.63           C
ATOM   2278  CG  GLN B 173      31.332  12.866  -8.102  1.00 84.31           C
ATOM   2279  CD  GLN B 173      30.616  12.840  -6.814  1.00 83.54           C
ATOM   2280  OE1 GLN B 173      29.385  12.804  -6.798  1.00 90.75           O
ATOM   2281  NE2 GLN B 173      31.347  12.903  -5.719  1.00 74.84           N
ATOM   2282  C   GLN B 173      31.728  12.643 -10.959  1.00 85.50           C
ATOM   2283  O   GLN B 173      32.716  11.949 -10.673  1.00 72.42           O
ATOM   2284  N   LYS B 174      30.762  12.256 -11.790  1.00 85.26           N
ATOM   2285  CA  LYS B 174      30.917  11.008 -12.490  1.00 88.11           C
ATOM   2286  CB  LYS B 174      29.682  10.703 -13.343  1.00 93.40           C
ATOM   2287  CG  LYS B 174      29.527   9.263 -13.793  1.00 95.19           C
ATOM   2288  CD  LYS B 174      28.512   8.406 -13.014  1.00101.11           C
ATOM   2289  CE  LYS B 174      28.803   6.824 -13.150  1.00107.14           C
ATOM   2290  NZ  LYS B 174      29.125   6.117 -14.525  1.00109.94           N
ATOM   2291  C   LYS B 174      32.282  11.064 -13.249  1.00 86.06           C
ATOM   2292  O   LYS B 174      33.009  10.099 -13.244  1.00 82.98           O
ATOM   2293  N   ALA B 175      32.665  12.213 -13.811  1.00 85.99           N
ATOM   2294  CA  ALA B 175      33.995  12.371 -14.444  1.00 82.08           C
ATOM   2295  CB  ALA B 175      34.028  13.551 -15.363  1.00 76.64           C
ATOM   2296  C   ALA B 175      35.142  12.456 -13.447  1.00 83.95           C
ATOM   2297  O   ALA B 175      36.064  11.659 -13.483  1.00 86.06           O
ATOM   2298  N   MET B 176      35.108  13.414 -12.539  1.00 89.53           N
ATOM   2299  CA  MET B 176      36.098  13.409 -11.459  1.00 90.11           C
ATOM   2300  CB  MET B 176      35.709  14.379 -10.371  1.00 89.39           C
ATOM   2301  CG  MET B 176      35.444  15.754 -10.831  1.00 88.14           C
ATOM   2302  SD  MET B 176      34.930  16.609  -9.355  1.00 93.43           S
ATOM   2303  CE  MET B 176      34.371  18.155 -10.060  1.00 95.61           C
ATOM   2304  C   MET B 176      36.246  12.016 -10.847  1.00 90.25           C
ATOM   2305  O   MET B 176      37.318  11.553 -10.638  1.00 92.27           O
ATOM   2306  N   ALA B 177      35.162  11.332 -10.568  1.00 95.05           N
ATOM   2307  CA  ALA B 177      35.306   9.986 -10.086  1.00 98.34           C
ATOM   2308  CB  ALA B 177      33.926   9.391  -9.653  1.00 96.67           C
ATOM   2309  C   ALA B 177      36.092   9.039 -11.033  1.00 96.83           C
ATOM   2310  O   ALA B 177      36.945   8.342 -10.536  1.00 97.03           O
ATOM   2311  N   ARG B 178      35.824   8.993 -12.352  1.00101.26           N
ATOM   2312  CA  ARG B 178      36.500   8.003 -13.263  1.00106.11           C
ATOM   2313  CB  ARG B 178      36.126   8.165 -14.753  1.00109.20           C
ATOM   2314  CG  ARG B 178      34.745   7.782 -15.129  1.00121.68           C
ATOM   2315  CD  ARG B 178      34.494   6.247 -15.164  1.00133.18           C
ATOM   2316  NE  ARG B 178      33.067   6.010 -15.464  1.00141.82           N
ATOM   2317  CZ  ARG B 178      32.578   5.375 -16.544  1.00144.18           C
ATOM   2318  NH1 ARG B 178      33.399   4.845 -17.455  1.00144.53           N
ATOM   2319  NH2 ARG B 178      31.253   5.251 -16.689  1.00143.58           N
ATOM   2320  C   ARG B 178      38.012   8.183 -13.188  1.00109.36           C
ATOM   2321  O   ARG B 178      38.809   7.240 -12.912  1.00106.61           O
ATOM   2322  N   GLN B 179      38.365   9.432 -13.458  1.00109.31           N
ATOM   2323  CA  GLN B 179      39.695   9.862 -13.647  1.00111.43           C
ATOM   2324  CB  GLN B 179      39.614  11.264 -14.161  1.00116.40           C
ATOM   2325  CG  GLN B 179      40.873  12.033 -14.132  1.00125.82           C
ATOM   2326  CD  GLN B 179      40.530  13.477 -14.279  1.00131.36           C
ATOM   2327  OE1 GLN B 179      39.431  13.806 -14.773  1.00130.93           O
ATOM   2328  NE2 GLN B 179      41.431  14.361 -13.837  1.00133.82           N
ATOM   2329  C   GLN B 179      40.500   9.749 -12.362  1.00110.29           C
ATOM   2330  O   GLN B 179      41.660   9.347 -12.400  1.00116.38           O
ATOM   2331  N   ALA B 180      39.889  10.052 -11.224  1.00108.02           N
ATOM   2332  CA  ALA B 180      40.558   9.879  -9.921  1.00106.11           C
ATOM   2333  CB  ALA B 180      39.802  10.608  -8.800  1.00103.02           C
ATOM   2334  C   ALA B 180      40.790   8.405  -9.571  1.00104.97           C
ATOM   2335  O   ALA B 180      41.598   8.075  -8.704  1.00104.22           O
ATOM   2336  N   GLU B 181      40.091   7.517 -10.259  1.00108.78           N
ATOM   2337  CA  GLU B 181      40.280   6.101 -10.029  1.00113.97           C
ATOM   2338  CB  GLU B 181      39.016   5.299 -10.300  1.00114.71           C
ATOM   2339  CG  GLU B 181      39.074   3.853  -9.840  1.00115.83           C
ATOM   2340  CD  GLU B 181      38.035   2.980 -10.549  1.00119.83           C
ATOM   2341  OE1 GLU B 181      38.042   1.773 -10.275  1.00121.74           O
ATOM   2342  OE2 GLU B 181      37.219   3.476 -11.385  1.00119.83           O
ATOM   2343  C   GLU B 181      41.365   5.664 -10.957  1.00118.75           C
ATOM   2344  O   GLU B 181      42.120   4.750 -10.605  1.00121.79           O
ATOM   2345  N   ALA B 182      41.441   6.299 -12.142  1.00120.41           N
ATOM   2346  CA  ALA B 182      42.563   6.063 -13.062  1.00119.21           C
ATOM   2347  CB  ALA B 182      42.470   6.924 -14.329  1.00112.11           C
ATOM   2348  C   ALA B 182      43.875   6.290 -12.286  1.00121.91           C
ATOM   2349  O   ALA B 182      44.697   5.366 -12.169  1.00118.25           O
ATOM   2350  N   GLU B 183      44.035   7.468 -11.683  1.00125.49           N
ATOM   2351  CA  GLU B 183      45.244   7.741 -10.908  1.00136.10           C
ATOM   2352  CB  GLU B 183      45.229   9.150 -10.314  1.00138.23           C
ATOM   2353  CG  GLU B 183      45.538  10.282 -11.299  1.00144.25           C
ATOM   2354  CD  GLU B 183      44.823  11.617 -10.923  1.00147.81           C
ATOM   2355  OE1 GLU B 183      44.459  11.829  -9.724  1.00151.58           O
ATOM   2356  OE2 GLU B 183      44.606  12.460 -11.838  1.00152.27           O
ATOM   2357  C   GLU B 183      45.592   6.700  -9.822  1.00136.05           C
ATOM   2358  O   GLU B 183      46.747   6.601  -9.441  1.00139.08           O
ATOM   2359  N   ARG B 184      44.620   5.932  -9.327  1.00138.26           N
ATOM   2360  CA  ARG B 184      44.898   4.875  -8.322  1.00138.75           C
ATOM   2361  CB  ARG B 184      43.664   4.518  -7.492  1.00134.54           C
ATOM   2362  CG  ARG B 184      43.086   5.645  -6.730  1.00128.33           C
ATOM   2363  CD  ARG B 184      41.899   5.161  -6.013  1.00124.13           C
ATOM   2364  NE  ARG B 184      41.359   6.230  -5.196  1.00121.00           N
ATOM   2365  CZ  ARG B 184      40.382   6.065  -4.316  1.00118.94           C
ATOM   2366  NH1 ARG B 184      39.846   4.858  -4.142  1.00115.79           N
ATOM   2367  NH2 ARG B 184      39.944   7.103  -3.610  1.00117.53           N
ATOM   2368  C   ARG B 184      45.379   3.597  -8.972  1.00142.87           C
ATOM   2369  O   ARG B 184      46.104   2.832  -8.342  1.00141.50           O
ATOM   2370  N   GLU B 185      44.912   3.357 -10.208  1.00150.04           N
ATOM   2371  CA  GLU B 185      45.369   2.256 -11.089  1.00155.34           C
ATOM   2372  CB  GLU B 185      44.412   2.034 -12.272  1.00155.28           C
ATOM   2373  CG  GLU B 185      43.021   1.518 -11.910  1.00156.86           C
ATOM   2374  CD  GLU B 185      41.974   1.847 -12.986  1.00157.50           C
ATOM   2375  OE1 GLU B 185      42.252   1.665 -14.196  1.00159.80           O
ATOM   2376  OE2 GLU B 185      40.859   2.281 -12.624  1.00156.73           O
ATOM   2377  C   GLU B 185      46.754   2.582 -11.649  1.00157.23           C
ATOM   2378  O   GLU B 185      47.482   1.671 -12.057  1.00158.85           O
ATOM   2379  N   ARG B 186      47.083   3.882 -11.692  1.00157.21           N
ATOM   2380  CA  ARG B 186      48.444   4.366 -11.946  1.00155.46           C
ATOM   2381  CB  ARG B 186      48.433   5.839 -12.359  1.00157.03           C
ATOM   2382  CG  ARG B 186      49.443   6.209 -13.428  1.00157.64           C
ATOM   2383  CD  ARG B 186      50.041   7.584 -13.153  1.00158.14           C
ATOM   2384  NE  ARG B 186      50.102   8.353 -14.394  1.00161.36           N
ATOM   2385  CZ  ARG B 186      49.147   9.198 -14.796  1.00163.56           C
ATOM   2386  NH1 ARG B 186      48.067   9.393 -14.032  1.00164.53           N
ATOM   2387  NH2 ARG B 186      49.269   9.859 -15.954  1.00164.09           N
ATOM   2388  C   ARG B 186      49.362   4.121 -10.715  1.00155.58           C
ATOM   2389  O   ARG B 186      50.115   3.148 -10.733  1.00156.54           O
ATOM   2390  N   ARG B 187      49.286   4.948  -9.654  1.00153.83           N
ATOM   2391  CA  ARG B 187      50.144   4.785  -8.442  1.00152.92           C
ATOM   2392  CB  ARG B 187      49.794   5.776  -7.340  1.00152.23           C
ATOM   2393  CG  ARG B 187      49.751   7.222  -7.687  1.00155.11           C
ATOM   2394  CD  ARG B 187      49.501   7.963  -6.376  1.00159.27           C
ATOM   2395  NE  ARG B 187      48.586   9.109  -6.494  1.00162.95           N
ATOM   2396  CZ  ARG B 187      48.159   9.844  -5.460  1.00163.15           C
ATOM   2397  NH1 ARG B 187      48.554   9.563  -4.216  1.00162.70           N
ATOM   2398  NH2 ARG B 187      47.334  10.868  -5.663  1.00162.52           N
ATOM   2399  C   ARG B 187      50.152   3.389  -7.788  1.00153.28           C
ATOM   2400  O   ARG B 187      50.964   3.135  -6.896  1.00151.99           O
ATOM   2401  N   ALA B 188      49.243   2.506  -8.203  1.00154.92           N
ATOM   2402  CA  ALA B 188      49.223   1.124  -7.726  1.00156.21           C
ATOM   2403  CB  ALA B 188      47.804   0.602  -7.614  1.00155.45           C
ATOM   2404  C   ALA B 188      50.074   0.190  -8.586  1.00158.62           C
ATOM   2405  O   ALA B 188      50.568  -0.814  -8.074  1.00159.80           O
ATOM   2406  N   ARG B 189      50.245   0.505  -9.874  1.00160.77           N
ATOM   2407  CA  ARG B 189      51.184  -0.249 -10.729  1.00165.49           C
ATOM   2408  CB  ARG B 189      50.639  -0.409 -12.146  1.00164.23           C
ATOM   2409  CG  ARG B 189      51.053   0.738 -13.021  1.00166.48           C
ATOM   2410  CD  ARG B 189      50.140   0.904 -14.155  1.00169.47           C
ATOM   2411  NE  ARG B 189      50.534   0.028 -15.238  1.00172.40           N
ATOM   2412  CZ  ARG B 189      49.929   0.007 -16.422  1.00174.84           C
ATOM   2413  NH1 ARG B 189      48.894   0.812 -16.669  1.00174.59           N
ATOM   2414  NH2 ARG B 189      50.360  -0.822 -17.362  1.00176.93           N
ATOM   2415  C   ARG B 189      52.646   0.312 -10.760  1.00167.72           C
ATOM   2416  O   ARG B 189      53.583  -0.480 -10.921  1.00168.95           O
ATOM   2417  N   ILE B 190      52.821   1.647 -10.635  1.00168.86           N
ATOM   2418  CA  ILE B 190      54.140   2.341 -10.411  1.00169.10           C
ATOM   2419  CB  ILE B 190      54.086   3.927 -10.705  1.00170.89           C
ATOM   2420  CG1 ILE B 190      54.538   4.257 -12.146  1.00171.17           C
ATOM   2421  CD1 ILE B 190      54.327   5.731 -12.581  1.00169.61           C
ATOM   2422  CG2 ILE B 190      54.876   4.808  -9.639  1.00168.52           C
ATOM   2423  C   ILE B 190      54.690   2.058  -9.000  1.00171.52           C
ATOM   2424  O   ILE B 190      55.704   2.638  -8.574  1.00171.49           O
ATOM   2425  N   THR B 191      53.999   1.164  -8.290  1.00173.51           N
ATOM   2426  CA  THR B 191      54.409   0.677  -6.974  1.00175.17           C
ATOM   2427  CB  THR B 191      53.546   1.335  -5.839  1.00174.43           C
ATOM   2428  OG1 THR B 191      53.607   2.767  -5.958  1.00173.02           O
ATOM   2429  CG2 THR B 191      54.027   0.932  -4.438  1.00173.70           C
ATOM   2430  C   THR B 191      54.412  -0.877  -6.926  1.00177.26           C
ATOM   2431  O   THR B 191      54.737  -1.461  -5.885  1.00177.71           O
ATOM   2432  N   LEU B 192      54.071  -1.537  -8.050  1.00179.02           N
ATOM   2433  CA  LEU B 192      54.211  -3.017  -8.184  1.00180.40           C
ATOM   2434  CB  LEU B 192      52.850  -3.730  -8.347  1.00179.63           C
ATOM   2435  CG  LEU B 192      52.625  -5.067  -7.599  1.00178.32           C
ATOM   2436  CD1 LEU B 192      51.996  -4.858  -6.206  1.00175.85           C
ATOM   2437  CD2 LEU B 192      51.786  -6.061  -8.418  1.00177.71           C
ATOM   2438  C   LEU B 192      55.237  -3.491  -9.255  1.00182.98           C
ATOM   2439  O   LEU B 192      55.576  -4.682  -9.314  1.00183.11           O
ATOM   2440  N   ALA B 193      55.730  -2.560 -10.080  1.00184.95           N
ATOM   2441  CA  ALA B 193      56.939  -2.785 -10.898  1.00185.83           C
ATOM   2442  CB  ALA B 193      56.745  -2.264 -12.345  1.00184.66           C
ATOM   2443  C   ALA B 193      58.204  -2.171 -10.250  1.00186.31           C
ATOM   2444  O   ALA B 193      59.331  -2.441 -10.691  1.00186.67           O
ATOM   2445  N   GLU B 194      58.005  -1.353  -9.209  1.00187.02           N
ATOM   2446  CA  GLU B 194      59.106  -0.726  -8.454  1.00188.22           C
ATOM   2447  CB  GLU B 194      58.684   0.662  -7.933  1.00189.03           C
ATOM   2448  CG  GLU B 194      59.523   1.233  -6.769  1.00189.13           C
ATOM   2449  CD  GLU B 194      60.709   2.082  -7.212  1.00189.46           C
ATOM   2450  OE1 GLU B 194      61.002   2.150  -8.428  1.00189.80           O
ATOM   2451  OE2 GLU B 194      61.350   2.694  -6.328  1.00189.16           O
ATOM   2452  C   GLU B 194      59.584  -1.616  -7.303  1.00188.75           C
ATOM   2453  O   GLU B 194      60.792  -1.741  -7.069  1.00188.85           O
ATOM   2454  N   ALA B 195      58.630  -2.216  -6.584  1.00189.00           N
ATOM   2455  CA  ALA B 195      58.924  -3.192  -5.534  1.00188.56           C
ATOM   2456  CB  ALA B 195      57.642  -3.621  -4.820  1.00186.97           C
ATOM   2457  C   ALA B 195      59.647  -4.404  -6.134  1.00189.43           C
ATOM   2458  O   ALA B 195      60.856  -4.583  -5.919  1.00190.37           O
ATOM   2459  N   GLU B 196      58.913  -5.202  -6.914  1.00187.91           N
ATOM   2460  CA  GLU B 196      59.447  -6.426  -7.529  1.00185.59           C
ATOM   2461  CB  GLU B 196      58.283  -7.391  -7.845  1.00185.67           C
ATOM   2462  CG  GLU B 196      58.618  -8.578  -8.757  1.00186.13           C
ATOM   2463  CD  GLU B 196      58.270  -8.261 -10.248  1.00186.67           C
ATOM   2464  OE1 GLU B 196      57.676  -7.181 -10.565  1.00187.51           O
ATOM   2465  OE2 GLU B 196      58.586  -9.098 -11.112  1.00186.54           O
ATOM   2466  C   GLU B 196      60.336  -6.158  -8.763  1.00182.56           C
ATOM   2467  O   GLU B 196      61.446  -5.609  -8.652  1.00177.43           O
TER
ATOM   2468  N   MET C  55      20.757  24.801 -15.707  1.00 93.69           N
ATOM   2469  CA  MET C  55      21.687  23.762 -15.199  1.00 94.75           C
ATOM   2470  CB  MET C  55      22.574  24.331 -14.114  1.00 98.34           C
ATOM   2471  CG  MET C  55      23.881  24.851 -14.625  1.00104.54           C
ATOM   2472  SD  MET C  55      25.347  23.915 -14.123  1.00104.38           S
ATOM   2473  CE  MET C  55      26.466  24.522 -15.384  1.00103.34           C
ATOM   2474  C   MET C  55      20.950  22.611 -14.593  1.00 92.40           C
ATOM   2475  O   MET C  55      19.869  22.784 -14.045  1.00 94.65           O
ATOM   2476  N   ILE C  56      21.555  21.433 -14.657  1.00 88.35           N
ATOM   2477  CA  ILE C  56      20.991  20.289 -13.976  1.00 83.79           C
ATOM   2478  CB  ILE C  56      20.459  19.292 -14.965  1.00 79.04           C
ATOM   2479  CG1 ILE C  56      19.173  19.910 -15.526  1.00 70.60           C
ATOM   2480  CD1 ILE C  56      18.584  19.254 -16.665  1.00 71.94           C
ATOM   2481  CG2 ILE C  56      20.282  17.883 -14.272  1.00 78.27           C
ATOM   2482  C   ILE C  56      22.011  19.722 -13.020  1.00 86.73           C
ATOM   2483  O   ILE C  56      23.180  19.516 -13.414  1.00 88.41           O
ATOM   2484  N   PHE C  57      21.600  19.530 -11.759  1.00 80.81           N
ATOM   2485  CA  PHE C  57      22.613  19.240 -10.747  1.00 80.88           C
ATOM   2486  CB  PHE C  57      22.531  20.255  -9.646  1.00 81.79           C
ATOM   2487  CG  PHE C  57      23.053  21.622  -9.975  1.00 77.57           C
ATOM   2488  CD1 PHE C  57      22.201  22.605 -10.466  1.00 80.51           C
ATOM   2489  CE1 PHE C  57      22.633  23.939 -10.682  1.00 79.58           C
ATOM   2490  CZ  PHE C  57      23.921  24.301 -10.375  1.00 81.02           C
ATOM   2491  CE2 PHE C  57      24.786  23.319  -9.822  1.00 82.94           C
ATOM   2492  CD2 PHE C  57      24.322  21.987  -9.611  1.00 78.42           C
ATOM   2493  C   PHE C  57      22.416  17.853 -10.130  1.00 79.58           C
ATOM   2494  O   PHE C  57      21.488  17.175 -10.479  1.00 83.53           O
ATOM   2495  N   GLU C  58      23.285  17.432  -9.226  1.00 76.60           N
ATOM   2496  CA  GLU C  58      23.203  16.112  -8.609  1.00 85.71           C
ATOM   2497  CB  GLU C  58      24.035  15.085  -9.407  1.00 85.73           C
ATOM   2498  CG  GLU C  58      23.288  14.031 -10.257  1.00 86.24           C
ATOM   2499  CD  GLU C  58      24.210  13.366 -11.339  1.00 91.80           C
ATOM   2500  OE1 GLU C  58      24.548  14.068 -12.344  1.00 92.77           O
ATOM   2501  OE2 GLU C  58      24.608  12.156 -11.202  1.00 91.47           O
ATOM   2502  C   GLU C  58      23.766  16.230  -7.184  1.00 87.14           C
ATOM   2503  O   GLU C  58      24.665  17.026  -6.951  1.00 89.46           O
ATOM   2504  N   LYS C  59      23.279  15.452  -6.223  1.00 87.51           N
ATOM   2505  CA  LYS C  59      23.954  15.449  -4.927  1.00 91.55           C
ATOM   2506  CB  LYS C  59      23.238  14.579  -3.901  1.00100.19           C
ATOM   2507  CG  LYS C  59      22.891  15.251  -2.568  1.00110.29           C
ATOM   2508  CD  LYS C  59      21.583  14.660  -2.047  1.00117.73           C
ATOM   2509  CE  LYS C  59      20.332  15.512  -2.634  1.00122.25           C
ATOM   2510  NZ  LYS C  59      18.964  14.819  -2.140  1.00121.13           N
ATOM   2511  C   LYS C  59      25.320  14.889  -5.191  1.00 90.85           C
ATOM   2512  O   LYS C  59      25.491  14.073  -6.099  1.00 95.95           O
ATOM   2513  N   ALA C  60      26.311  15.343  -4.449  1.00 87.31           N
ATOM   2514  CA  ALA C  60      27.654  14.873  -4.714  1.00 86.43           C
ATOM   2515  CB  ALA C  60      28.645  15.960  -4.502  1.00 83.06           C
ATOM   2516  C   ALA C  60      27.844  13.823  -3.687  1.00 88.02           C
ATOM   2517  O   ALA C  60      27.226  13.930  -2.611  1.00 94.81           O
ATOM   2518  N   VAL C  61      28.687  12.827  -3.972  1.00 83.64           N
ATOM   2519  CA  VAL C  61      28.933  11.802  -2.980  1.00 80.78           C
ATOM   2520  CB  VAL C  61      29.091  10.390  -3.542  1.00 75.99           C
ATOM   2521  CG1 VAL C  61      29.066   9.403  -2.415  1.00 74.48           C
ATOM   2522  CG2 VAL C  61      27.963  10.053  -4.486  1.00 75.34           C
ATOM   2523  C   VAL C  61      30.160  12.182  -2.251  1.00 83.13           C
ATOM   2524  O   VAL C  61      31.237  11.996  -2.718  1.00 90.15           O
ATOM   2525  N   ILE C  62      29.986  12.717  -1.074  1.00 89.53           N
ATOM   2526  CA  ILE C  62      31.116  13.089  -0.252  1.00 98.60           C
ATOM   2527  CB  ILE C  62      30.848  14.491   0.348  1.00103.56           C
ATOM   2528  CG1 ILE C  62      29.962  14.398   1.600  1.00110.77           C
ATOM   2529  CD1 ILE C  62      28.482  13.729   1.398  1.00120.30           C
ATOM   2530  CG2 ILE C  62      30.184  15.407  -0.686  1.00103.58           C
ATOM   2531  C   ILE C  62      31.434  12.049   0.880  1.00 99.57           C
ATOM   2532  O   ILE C  62      30.679  11.089   1.144  1.00 94.43           O
ATOM   2533  N   VAL C  63      32.565  12.261   1.545  1.00102.10           N
ATOM   2534  CA  VAL C  63      32.877  11.580   2.809  1.00101.26           C
ATOM   2535  CB  VAL C  63      34.220  12.019   3.245  1.00 97.32           C
ATOM   2536  CG1 VAL C  63      34.919  10.892   3.961  1.00 93.89           C
ATOM   2537  CG2 VAL C  63      34.958  12.452   1.965  1.00100.64           C
ATOM   2538  C   VAL C  63      31.886  12.036   3.857  1.00101.31           C
ATOM   2539  O   VAL C  63      31.583  13.238   3.939  1.00104.57           O
ATOM   2540  N   ASP C  64      31.351  11.103   4.638  1.00 97.48           N
ATOM   2541  CA  ASP C  64      30.308  11.504   5.569  1.00 94.06           C
ATOM   2542  CB  ASP C  64      29.238  10.448   5.723  1.00 98.49           C
ATOM   2543  CG  ASP C  64      28.278  10.413   4.568  1.00104.06           C
ATOM   2544  OD1 ASP C  64      27.792  11.507   4.144  1.00108.14           O
ATOM   2545  OD2 ASP C  64      28.000   9.273   4.101  1.00102.73           O
ATOM   2546  C   ASP C  64      30.916  11.809   6.902  1.00 90.18           C
ATOM   2547  O   ASP C  64      31.614  10.970   7.466  1.00 84.96           O
ATOM   2548  N   LEU C  65      30.647  13.024   7.379  1.00 87.48           N
ATOM   2549  CA  LEU C  65      31.176  13.505   8.643  1.00 86.36           C
ATOM   2550  CB  LEU C  65      31.183  15.044   8.688  1.00 84.80           C
ATOM   2551  CG  LEU C  65      32.423  15.903   8.410  1.00 79.52           C
ATOM   2552  CD1 LEU C  65      33.256  15.336   7.325  1.00 77.77           C
ATOM   2553  CD2 LEU C  65      31.992  17.262   7.998  1.00 79.41           C
ATOM   2554  C   LEU C  65      30.315  12.971   9.785  1.00 92.80           C
ATOM   2555  O   LEU C  65      30.784  12.851  10.913  1.00 96.01           O
ATOM   2556  N   ARG C  66      29.042  12.701   9.499  1.00 94.55           N
ATOM   2557  CA  ARG C  66      28.089  12.266  10.498  1.00 92.16           C
ATOM   2558  CB  ARG C  66      27.048  13.333  10.723  1.00 92.58           C
ATOM   2559  CG  ARG C  66      27.551  14.327  11.684  1.00102.30           C
ATOM   2560  CD  ARG C  66      26.649  15.529  11.799  1.00111.27           C
ATOM   2561  NE  ARG C  66      25.746  15.444  12.951  1.00117.35           N
ATOM   2562  CZ  ARG C  66      26.104  15.648  14.224  1.00119.99           C
ATOM   2563  NH1 ARG C  66      25.164  15.540  15.158  1.00122.66           N
ATOM   2564  NH2 ARG C  66      27.375  15.941  14.569  1.00113.72           N
ATOM   2565  C   ARG C  66      27.453  11.032   9.950  1.00 93.29           C
ATOM   2566  O   ARG C  66      27.659  10.710   8.792  1.00 95.96           O
ATOM   2567  N   THR C  67      26.668  10.334  10.759  1.00 93.23           N
ATOM   2568  CA  THR C  67      26.069   9.108  10.286  1.00 91.83           C
ATOM   2569  CB  THR C  67      25.684   8.237  11.456  1.00 90.89           C
ATOM   2570  OG1 THR C  67      26.866   7.919  12.226  1.00 93.71           O
ATOM   2571  CG2 THR C  67      25.059   6.984  10.933  1.00 90.45           C
ATOM   2572  C   THR C  67      24.848   9.395   9.440  1.00 92.56           C
ATOM   2573  O   THR C  67      23.946  10.017   9.953  1.00 93.24           O
ATOM   2574  N   GLN C  68      24.839   9.007   8.154  1.00 95.11           N
ATOM   2575  CA  GLN C  68      23.590   8.931   7.351  1.00 97.07           C
ATOM   2576  CB  GLN C  68      23.920   8.697   5.867  1.00 98.67           C
ATOM   2577  CG  GLN C  68      24.908   9.726   5.181  1.00108.13           C
ATOM   2578  CD  GLN C  68      24.833   9.785   3.548  1.00109.20           C
ATOM   2579  OE1 GLN C  68      23.981  10.495   2.981  1.00110.75           O
ATOM   2580  NE2 GLN C  68      25.744   9.058   2.844  1.00108.91           N
ATOM   2581  C   GLN C  68      22.597   7.814   7.911  1.00 96.01           C
ATOM   2582  O   GLN C  68      23.043   6.868   8.575  1.00 97.39           O
ATOM   2583  N   VAL C  69      21.278   7.931   7.685  1.00 90.87           N
ATOM   2584  CA  VAL C  69      20.272   6.918   8.117  1.00 85.22           C
ATOM   2585  CB  VAL C  69      19.222   7.584   9.096  1.00 83.45           C
ATOM   2586  CG1 VAL C  69      18.032   6.706   9.368  1.00 84.00           C
ATOM   2587  CG2 VAL C  69      19.844   7.957  10.449  1.00 83.07           C
ATOM   2588  C   VAL C  69      19.595   6.306   6.863  1.00 79.26           C
ATOM   2589  O   VAL C  69      19.486   6.964   5.871  1.00 83.93           O
ATOM   2590  N   LEU C  70      19.145   5.067   6.847  1.00 78.83           N
ATOM   2591  CA  LEU C  70      18.445   4.572   5.619  1.00 80.86           C
ATOM   2592  CB  LEU C  70      19.464   4.008   4.577  1.00 79.58           C
ATOM   2593  CG  LEU C  70      19.030   2.915   3.572  1.00 79.49           C
ATOM   2594  CD1 LEU C  70      17.835   3.389   2.725  1.00 89.38           C
ATOM   2595  CD2 LEU C  70      20.100   2.458   2.629  1.00 77.54           C
ATOM   2596  C   LEU C  70      17.272   3.566   5.880  1.00 82.22           C
ATOM   2597  O   LEU C  70      17.516   2.414   6.223  1.00 87.53           O
ATOM   2598  N   ASP C  71      16.016   3.959   5.689  1.00 80.56           N
ATOM   2599  CA  ASP C  71      14.938   3.024   6.045  1.00 84.82           C
ATOM   2600  CB  ASP C  71      13.544   3.680   6.128  1.00 87.20           C
ATOM   2601  CG  ASP C  71      13.463   4.729   7.244  1.00 97.30           C
ATOM   2602  OD1 ASP C  71      13.552   4.354   8.437  1.00102.78           O
ATOM   2603  OD2 ASP C  71      13.324   5.945   6.960  1.00 99.95           O
ATOM   2604  C   ASP C  71      14.969   1.864   5.080  1.00 84.67           C
ATOM   2605  O   ASP C  71      14.972   2.084   3.860  1.00 93.56           O
ATOM   2606  N   VAL C  72      15.049   0.648   5.628  1.00 78.18           N
ATOM   2607  CA  VAL C  72      14.952  -0.592   4.859  1.00 77.30           C
ATOM   2608  CB  VAL C  72      15.689  -1.798   5.570  1.00 76.34           C
ATOM   2609  CG1 VAL C  72      15.607  -3.066   4.673  1.00 72.49           C
ATOM   2610  CG2 VAL C  72      17.163  -1.446   6.043  1.00 62.60           C
ATOM   2611  C   VAL C  72      13.479  -1.000   4.623  1.00 80.44           C
ATOM   2612  O   VAL C  72      12.803  -1.404   5.588  1.00 88.17           O
ATOM   2613  N   PRO C  73      12.971  -0.909   3.359  1.00 78.31           N
ATOM   2614  CA  PRO C  73      11.613  -1.353   2.954  1.00 77.37           C
ATOM   2615  CB  PRO C  73      11.759  -1.636   1.441  1.00 73.63           C
ATOM   2616  CG  PRO C  73      12.941  -0.924   1.001  1.00 72.94           C
ATOM   2617  CD  PRO C  73      13.691  -0.351   2.206  1.00 76.16           C
ATOM   2618  C   PRO C  73      11.158  -2.642   3.609  1.00 78.58           C
ATOM   2619  O   PRO C  73      11.906  -3.608   3.680  1.00 82.27           O
ATOM   2620  N   VAL C  74       9.923  -2.669   4.047  1.00 83.37           N
ATOM   2621  CA  VAL C  74       9.378  -3.855   4.719  1.00 88.88           C
ATOM   2622  CB  VAL C  74       7.842  -3.686   4.951  1.00 88.02           C
ATOM   2623  CG1 VAL C  74       7.264  -4.916   5.638  1.00 80.66           C
ATOM   2624  CG2 VAL C  74       7.541  -2.330   5.702  1.00 87.56           C
ATOM   2625  C   VAL C  74       9.568  -5.134   3.913  1.00 87.67           C
ATOM   2626  O   VAL C  74       9.293  -5.137   2.728  1.00 90.38           O
ATOM   2627  N   GLN C  75      10.026  -6.201   4.562  1.00 87.15           N
ATOM   2628  CA  GLN C  75       9.998  -7.549   3.999  1.00 87.32           C
ATOM   2629  CB  GLN C  75      11.282  -8.271   4.345  1.00 83.72           C
ATOM   2630  CG  GLN C  75      12.518  -7.562   3.974  1.00 82.28           C
ATOM   2631  CD  GLN C  75      12.566  -7.326   2.509  1.00 84.49           C
ATOM   2632  OE1 GLN C  75      12.539  -8.287   1.716  1.00 84.94           O
ATOM   2633  NE2 GLN C  75      12.634  -6.037   2.113  1.00 83.65           N
ATOM   2634  C   GLN C  75       8.916  -8.315   4.729  1.00 93.11           C
ATOM   2635  O   GLN C  75       8.868  -8.280   5.962  1.00 96.70           O
ATOM   2636  N   GLU C  76       8.053  -9.015   4.005  1.00 95.59           N
ATOM   2637  CA  GLU C  76       7.106  -9.920   4.656  1.00 98.19           C
ATOM   2638  CB  GLU C  76       5.673  -9.658   4.203  1.00103.28           C
ATOM   2639  CG  GLU C  76       4.750 -10.889   4.260  1.00110.69           C
ATOM   2640  CD  GLU C  76       3.327 -10.614   3.735  1.00111.89           C
ATOM   2641  OE1 GLU C  76       2.886  -9.434   3.801  1.00115.92           O
ATOM   2642  OE2 GLU C  76       2.664 -11.583   3.262  1.00115.46           O
ATOM   2643  C   GLU C  76       7.534 -11.286   4.257  1.00 91.50           C
ATOM   2644  O   GLU C  76       7.853 -11.502   3.112  1.00 94.65           O
ATOM   2645  N   THR C  77       7.561 -12.199   5.209  1.00 92.57           N
ATOM   2646  CA  THR C  77       8.166 -13.536   5.039  1.00 93.01           C
ATOM   2647  CB  THR C  77       9.684 -13.414   4.718  1.00 92.54           C
ATOM   2648  OG1 THR C  77      10.314 -14.701   4.740  1.00100.69           O
ATOM   2649  CG2 THR C  77      10.365 -12.569   5.726  1.00 95.35           C
ATOM   2650  C   THR C  77       7.895 -14.489   6.244  1.00 92.11           C
ATOM   2651  O   THR C  77       7.300 -14.099   7.265  1.00 91.45           O
ATOM   2652  N   ILE C  78       8.320 -15.737   6.109  1.00 91.97           N
ATOM   2653  CA  ILE C  78       8.024 -16.768   7.098  1.00 95.75           C
ATOM   2654  CB  ILE C  78       7.431 -18.053   6.408  1.00 94.33           C
ATOM   2655  CG1 ILE C  78       5.943 -17.802   6.090  1.00 97.92           C
ATOM   2656  CD1 ILE C  78       5.488 -18.016   4.635  1.00100.13           C
ATOM   2657  CG2 ILE C  78       7.517 -19.247   7.318  1.00 88.43           C
ATOM   2658  C   ILE C  78       9.240 -17.039   7.983  1.00 97.47           C
ATOM   2659  O   ILE C  78      10.344 -17.178   7.467  1.00104.65           O
ATOM   2660  N   THR C  79       9.041 -17.076   9.305  1.00 97.72           N
ATOM   2661  CA  THR C  79      10.110 -17.348  10.287  1.00 97.47           C
ATOM   2662  CB  THR C  79       9.638 -16.984  11.716  1.00 98.96           C
ATOM   2663  OG1 THR C  79       8.475 -17.752  12.075  1.00101.56           O
ATOM   2664  CG2 THR C  79       9.271 -15.488  11.803  1.00 98.80           C
ATOM   2665  C   THR C  79      10.517 -18.833  10.197  1.00100.45           C
ATOM   2666  O   THR C  79       9.812 -19.613   9.534  1.00101.52           O
ATOM   2667  N   LYS C  80      11.632 -19.244  10.816  1.00100.81           N
ATOM   2668  CA  LYS C  80      12.016 -20.673  10.765  1.00104.07           C
ATOM   2669  CB  LYS C  80      13.262 -20.933  11.599  1.00104.68           C
ATOM   2670  CG  LYS C  80      13.822 -22.337  11.447  1.00111.37           C
ATOM   2671  CD  LYS C  80      15.009 -22.528  12.419  1.00116.74           C
ATOM   2672  CE  LYS C  80      16.196 -23.308  11.767  1.00119.96           C
ATOM   2673  NZ  LYS C  80      17.327 -23.543  12.735  1.00115.16           N
ATOM   2674  C   LYS C  80      10.830 -21.491  11.292  1.00106.52           C
ATOM   2675  O   LYS C  80      10.247 -22.328  10.588  1.00107.08           O
ATOM   2676  N   ASP C  81      10.544 -21.218  12.570  1.00109.20           N
ATOM   2677  CA  ASP C  81       9.264 -21.310  13.287  1.00104.28           C
ATOM   2678  CB  ASP C  81       9.091 -20.016  14.058  1.00105.57           C
ATOM   2679  CG  ASP C  81       9.062 -20.241  15.505  1.00108.61           C
ATOM   2680  OD1 ASP C  81       8.164 -20.981  15.906  1.00110.54           O
ATOM   2681  OD2 ASP C  81       9.917 -19.708  16.246  1.00111.34           O
ATOM   2682  C   ASP C  81       7.985 -21.490  12.540  1.00104.16           C
ATOM   2683  O   ASP C  81       7.053 -22.067  13.082  1.00108.70           O
ATOM   2684  N   ASN C  82       7.917 -20.938  11.333  1.00103.05           N
ATOM   2685  CA  ASN C  82       6.734 -20.973  10.470  1.00101.23           C
ATOM   2686  CB  ASN C  82       5.987 -22.291  10.537  1.00101.19           C
ATOM   2687  CG  ASN C  82       6.377 -23.204   9.425  1.00103.86           C
ATOM   2688  OD1 ASN C  82       7.004 -22.795   8.439  1.00 98.45           O
ATOM   2689  ND2 ASN C  82       6.017 -24.467   9.570  1.00110.20           N
ATOM   2690  C   ASN C  82       5.725 -19.875  10.605  1.00100.80           C
ATOM   2691  O   ASN C  82       4.689 -19.955   9.960  1.00104.00           O
ATOM   2692  N   VAL C  83       5.999 -18.851  11.404  1.00 96.66           N
ATOM   2693  CA  VAL C  83       5.052 -17.752  11.490  1.00 94.01           C
ATOM   2694  CB  VAL C  83       5.109 -17.129  12.845  1.00 91.66           C
ATOM   2695  CG1 VAL C  83       3.738 -16.482  13.155  1.00 92.57           C
ATOM   2696  CG2 VAL C  83       5.527 -18.165  13.869  1.00 84.09           C
ATOM   2697  C   VAL C  83       5.259 -16.665  10.407  1.00 94.48           C
ATOM   2698  O   VAL C  83       6.389 -16.235  10.190  1.00 93.63           O
ATOM   2699  N   PRO C  84       4.174 -16.237   9.715  1.00 94.32           N
ATOM   2700  CA  PRO C  84       4.182 -15.113   8.741  1.00 95.20           C
ATOM   2701  CB  PRO C  84       2.735 -15.016   8.241  1.00 93.39           C
ATOM   2702  CG  PRO C  84       2.034 -16.160   8.775  1.00 94.47           C
ATOM   2703  CD  PRO C  84       2.851 -16.855   9.837  1.00 93.82           C
ATOM   2704  C   PRO C  84       4.526 -13.814   9.427  1.00 95.44           C
ATOM   2705  O   PRO C  84       4.088 -13.601  10.571  1.00 97.17           O
ATOM   2706  N   VAL C  85       5.293 -12.954   8.746  1.00 92.63           N
ATOM   2707  CA  VAL C  85       5.944 -11.817   9.435  1.00 90.12           C
ATOM   2708  CB  VAL C  85       7.245 -12.301  10.106  1.00 84.37           C
ATOM   2709  CG1 VAL C  85       8.249 -11.283  10.005  1.00 86.53           C
ATOM   2710  CG2 VAL C  85       7.014 -12.655  11.544  1.00 78.67           C
ATOM   2711  C   VAL C  85       6.223 -10.605   8.530  1.00 88.42           C
ATOM   2712  O   VAL C  85       6.715 -10.755   7.415  1.00 87.92           O
ATOM   2713  N   ARG C  86       5.895  -9.408   8.997  1.00 84.97           N
ATOM   2714  CA  ARG C  86       6.288  -8.208   8.260  1.00 85.70           C
ATOM   2715  CB  ARG C  86       5.107  -7.244   8.061  1.00 85.26           C
ATOM   2716  CG  ARG C  86       4.061  -7.685   7.027  1.00 87.40           C
ATOM   2717  CD  ARG C  86       3.215  -6.515   6.453  1.00 89.52           C
ATOM   2718  NE  ARG C  86       3.078  -6.813   5.021  1.00104.98           N
ATOM   2719  CZ  ARG C  86       3.407  -6.014   3.982  1.00110.78           C
ATOM   2720  NH1 ARG C  86       3.841  -4.755   4.174  1.00110.90           N
ATOM   2721  NH2 ARG C  86       3.273  -6.471   2.721  1.00109.22           N
ATOM   2722  C   ARG C  86       7.401  -7.552   9.075  1.00 86.67           C
ATOM   2723  O   ARG C  86       7.218  -7.293  10.261  1.00 90.73           O
ATOM   2724  N   VAL C  87       8.575  -7.330   8.496  1.00 84.03           N
ATOM   2725  CA  VAL C  87       9.674  -6.824   9.320  1.00 84.29           C
ATOM   2726  CB  VAL C  87      10.685  -7.908   9.779  1.00 83.78           C
ATOM   2727  CG1 VAL C  87      11.832  -7.235  10.498  1.00 87.82           C
ATOM   2728  CG2 VAL C  87      10.096  -8.870  10.728  1.00 78.67           C
ATOM   2729  C   VAL C  87      10.471  -5.791   8.583  1.00 86.46           C
ATOM   2730  O   VAL C  87      10.741  -5.940   7.374  1.00 86.96           O
ATOM   2731  N   ASN C  88      10.866  -4.748   9.312  1.00 84.52           N
ATOM   2732  CA  ASN C  88      11.630  -3.670   8.680  1.00 87.67           C
ATOM   2733  CB  ASN C  88      10.707  -2.569   8.094  1.00 85.45           C
ATOM   2734  CG  ASN C  88      10.104  -1.672   9.156  1.00 84.80           C
ATOM   2735  OD1 ASN C  88      10.407  -1.784  10.346  1.00 81.58           O
ATOM   2736  ND2 ASN C  88       9.257  -0.752   8.721  1.00 86.71           N
ATOM   2737  C   ASN C  88      12.726  -3.140   9.605  1.00 84.87           C
ATOM   2738  O   ASN C  88      12.689  -3.425  10.795  1.00 85.24           O
ATOM   2739  N   ALA C  89      13.704  -2.409   9.061  1.00 79.43           N
ATOM   2740  CA  ALA C  89      14.866  -2.058   9.849  1.00 78.69           C
ATOM   2741  CB  ALA C  89      15.868  -3.117   9.688  1.00 81.19           C
ATOM   2742  C   ALA C  89      15.476  -0.724   9.462  1.00 79.23           C
ATOM   2743  O   ALA C  89      15.253  -0.265   8.368  1.00 84.75           O
ATOM   2744  N   VAL C  90      16.265  -0.117  10.335  1.00 76.07           N
ATOM   2745  CA  VAL C  90      17.048   1.029   9.940  1.00 79.46           C
ATOM   2746  CB  VAL C  90      17.058   2.120  10.998  1.00 82.09           C
ATOM   2747  CG1 VAL C  90      17.163   3.424  10.297  1.00 85.65           C
ATOM   2748  CG2 VAL C  90      15.849   2.071  11.902  1.00 84.36           C
ATOM   2749  C   VAL C  90      18.535   0.660   9.790  1.00 82.15           C
ATOM   2750  O   VAL C  90      19.126   0.108  10.731  1.00 84.46           O
ATOM   2751  N   VAL C  91      19.146   1.014   8.656  1.00 77.08           N
ATOM   2752  CA  VAL C  91      20.585   0.850   8.459  1.00 75.15           C
ATOM   2753  CB  VAL C  91      20.861   0.413   7.000  1.00 74.24           C
ATOM   2754  CG1 VAL C  91      22.311   0.520   6.629  1.00 76.68           C
ATOM   2755  CG2 VAL C  91      20.481  -0.967   6.829  1.00 75.07           C
ATOM   2756  C   VAL C  91      21.312   2.154   8.771  1.00 76.12           C
ATOM   2757  O   VAL C  91      20.969   3.191   8.219  1.00 78.73           O
ATOM   2758  N   TYR C  92      22.313   2.128   9.642  1.00 78.94           N
ATOM   2759  CA  TYR C  92      23.138   3.329   9.854  1.00 83.73           C
ATOM   2760  CB  TYR C  92      23.360   3.618  11.329  1.00 86.04           C
ATOM   2761  CG  TYR C  92      22.088   3.724  12.110  1.00 88.70           C
ATOM   2762  CD1 TYR C  92      21.295   2.609  12.242  1.00 94.46           C
ATOM   2763  CE1 TYR C  92      20.117   2.651  12.930  1.00 95.43           C
ATOM   2764  CZ  TYR C  92      19.729   3.806  13.541  1.00 90.27           C
ATOM   2765  OH  TYR C  92      18.534   3.646  14.170  1.00 93.10           O
ATOM   2766  CE2 TYR C  92      20.491   4.966  13.462  1.00 83.07           C
ATOM   2767  CD2 TYR C  92      21.668   4.920  12.726  1.00 84.00           C
ATOM   2768  C   TYR C  92      24.486   3.183   9.166  1.00 89.05           C
ATOM   2769  O   TYR C  92      25.162   2.150   9.314  1.00 94.13           O
ATOM   2770  N   PHE C  93      24.896   4.226   8.444  1.00 86.64           N
ATOM   2771  CA  PHE C  93      26.074   4.141   7.610  1.00 83.70           C
ATOM   2772  CB  PHE C  93      25.677   3.514   6.302  1.00 84.21           C
ATOM   2773  CG  PHE C  93      24.976   4.454   5.355  1.00 86.71           C
ATOM   2774  CD1 PHE C  93      25.651   5.013   4.280  1.00 87.05           C
ATOM   2775  CE1 PHE C  93      24.994   5.870   3.368  1.00 89.71           C
ATOM   2776  CZ  PHE C  93      23.659   6.179   3.543  1.00 88.04           C
ATOM   2777  CE2 PHE C  93      22.971   5.624   4.606  1.00 90.03           C
ATOM   2778  CD2 PHE C  93      23.627   4.744   5.500  1.00 89.88           C
ATOM   2779  C   PHE C  93      26.805   5.464   7.364  1.00 85.73           C
ATOM   2780  O   PHE C  93      26.332   6.537   7.715  1.00 88.88           O
ATOM   2781  N   ARG C  94      27.987   5.363   6.776  1.00 86.66           N
ATOM   2782  CA  ARG C  94      28.791   6.502   6.383  1.00 86.53           C
ATOM   2783  CB  ARG C  94      29.753   6.844   7.480  1.00 86.81           C
ATOM   2784  CG  ARG C  94      29.146   7.667   8.609  1.00 99.99           C
ATOM   2785  CD  ARG C  94      29.844   7.380   9.967  1.00108.97           C
ATOM   2786  NE  ARG C  94      31.215   6.994   9.680  1.00114.81           N
ATOM   2787  CZ  ARG C  94      32.277   7.709   9.996  1.00120.46           C
ATOM   2788  NH1 ARG C  94      32.138   8.841  10.701  1.00122.97           N
ATOM   2789  NH2 ARG C  94      33.476   7.260   9.627  1.00122.84           N
ATOM   2790  C   ARG C  94      29.570   6.115   5.122  1.00 90.89           C
ATOM   2791  O   ARG C  94      30.091   4.983   5.029  1.00 94.27           O
ATOM   2792  N   VAL C  95      29.607   7.016   4.132  1.00 90.56           N
ATOM   2793  CA  VAL C  95      30.395   6.793   2.919  1.00 91.36           C
ATOM   2794  CB  VAL C  95      30.070   7.799   1.795  1.00 91.09           C
ATOM   2795  CG1 VAL C  95      31.094   7.726   0.700  1.00 88.48           C
ATOM   2796  CG2 VAL C  95      28.699   7.559   1.227  1.00 91.69           C
ATOM   2797  C   VAL C  95      31.808   7.052   3.367  1.00 95.71           C
ATOM   2798  O   VAL C  95      32.095   8.069   4.062  1.00 99.14           O
ATOM   2799  N   VAL C  96      32.694   6.128   2.996  1.00 96.76           N
ATOM   2800  CA  VAL C  96      34.086   6.222   3.430  1.00 93.36           C
ATOM   2801  CB  VAL C  96      34.377   5.150   4.474  1.00 92.56           C
ATOM   2802  CG1 VAL C  96      35.728   4.571   4.304  1.00 96.36           C
ATOM   2803  CG2 VAL C  96      34.172   5.733   5.896  1.00 93.79           C
ATOM   2804  C   VAL C  96      35.104   6.354   2.275  1.00 91.39           C
ATOM   2805  O   VAL C  96      36.090   7.049   2.411  1.00 92.80           O
ATOM   2806  N   ASP C  97      34.819   5.768   1.127  1.00 87.58           N
ATOM   2807  CA  ASP C  97      35.620   5.999  -0.034  1.00 86.70           C
ATOM   2808  CB  ASP C  97      36.280   4.667  -0.380  1.00 89.44           C
ATOM   2809  CG  ASP C  97      37.199   4.744  -1.577  1.00 92.13           C
ATOM   2810  OD1 ASP C  97      36.877   5.437  -2.561  1.00 92.35           O
ATOM   2811  OD2 ASP C  97      38.244   4.063  -1.553  1.00 95.59           O
ATOM   2812  C   ASP C  97      34.663   6.497  -1.156  1.00 88.29           C
ATOM   2813  O   ASP C  97      34.077   5.693  -1.887  1.00 92.08           O
ATOM   2814  N   PRO C  98      34.474   7.820  -1.295  1.00 84.92           N
ATOM   2815  CA  PRO C  98      33.541   8.290  -2.338  1.00 84.89           C
ATOM   2816  CB  PRO C  98      33.584   9.807  -2.234  1.00 83.67           C
ATOM   2817  CG  PRO C  98      34.111  10.086  -0.886  1.00 90.32           C
ATOM   2818  CD  PRO C  98      35.027   8.928  -0.505  1.00 87.70           C
ATOM   2819  C   PRO C  98      33.892   7.864  -3.750  1.00 88.41           C
ATOM   2820  O   PRO C  98      32.997   7.684  -4.577  1.00 89.16           O
ATOM   2821  N   VAL C  99      35.172   7.696  -4.054  1.00 90.84           N
ATOM   2822  CA  VAL C  99      35.503   7.196  -5.387  1.00 90.25           C
ATOM   2823  CB  VAL C  99      37.024   7.240  -5.700  1.00 87.31           C
ATOM   2824  CG1 VAL C  99      37.303   6.699  -7.107  1.00 85.55           C
ATOM   2825  CG2 VAL C  99      37.540   8.637  -5.592  1.00 83.39           C
ATOM   2826  C   VAL C  99      34.898   5.789  -5.556  1.00 91.56           C
ATOM   2827  O   VAL C  99      34.186   5.497  -6.527  1.00 90.70           O
ATOM   2828  N   LYS C 100      35.137   4.920  -4.587  1.00 94.50           N
ATOM   2829  CA  LYS C 100      34.596   3.568  -4.716  1.00 98.68           C
ATOM   2830  CB  LYS C 100      34.957   2.709  -3.510  1.00 98.18           C
ATOM   2831  CG  LYS C 100      36.108   1.741  -3.721  1.00 99.27           C
ATOM   2832  CD  LYS C 100      36.688   1.472  -2.358  1.00102.48           C
ATOM   2833  CE  LYS C 100      37.486   0.205  -2.237  1.00100.12           C
ATOM   2834  NZ  LYS C 100      38.300   0.571  -1.050  1.00100.26           N
ATOM   2835  C   LYS C 100      33.084   3.614  -4.936  1.00 97.47           C
ATOM   2836  O   LYS C 100      32.563   2.930  -5.816  1.00 96.44           O
ATOM   2837  N   ALA C 101      32.423   4.480  -4.163  1.00 95.28           N
ATOM   2838  CA  ALA C 101      30.970   4.594  -4.122  1.00 93.55           C
ATOM   2839  CB  ALA C 101      30.574   5.482  -2.993  1.00 90.22           C
ATOM   2840  C   ALA C 101      30.336   5.122  -5.404  1.00 94.56           C
ATOM   2841  O   ALA C 101      29.203   4.734  -5.741  1.00 96.71           O
ATOM   2842  N   VAL C 102      31.032   6.028  -6.098  1.00 89.38           N
ATOM   2843  CA  VAL C 102      30.456   6.597  -7.297  1.00 83.04           C
ATOM   2844  CB  VAL C 102      31.073   7.912  -7.671  1.00 75.84           C
ATOM   2845  CG1 VAL C 102      30.266   8.487  -8.757  1.00 74.44           C
ATOM   2846  CG2 VAL C 102      31.038   8.862  -6.515  1.00 73.09           C
ATOM   2847  C   VAL C 102      30.677   5.622  -8.430  1.00 87.71           C
ATOM   2848  O   VAL C 102      29.933   5.621  -9.432  1.00 91.16           O
ATOM   2849  N   THR C 103      31.662   4.750  -8.217  1.00 89.84           N
ATOM   2850  CA  THR C 103      32.302   4.001  -9.273  1.00 89.99           C
ATOM   2851  CB  THR C 103      33.786   4.120  -9.108  1.00 90.18           C
ATOM   2852  OG1 THR C 103      34.168   5.373  -9.669  1.00 91.88           O
ATOM   2853  CG2 THR C 103      34.494   3.045  -9.860  1.00 94.82           C
ATOM   2854  C   THR C 103      31.920   2.537  -9.435  1.00 93.23           C
ATOM   2855  O   THR C 103      31.868   2.085 -10.559  1.00 90.41           O
ATOM   2856  N   GLN C 104      31.666   1.801  -8.339  1.00 97.63           N
ATOM   2857  CA  GLN C 104      31.453   0.330  -8.384  1.00 94.11           C
ATOM   2858  CB  GLN C 104      32.017  -0.363  -7.149  1.00 92.46           C
ATOM   2859  CG  GLN C 104      33.435   0.015  -6.802  1.00 99.76           C
ATOM   2860  CD  GLN C 104      34.377   0.050  -8.019  1.00104.48           C
ATOM   2861  OE1 GLN C 104      34.627  -0.978  -8.647  1.00106.36           O
ATOM   2862  NE2 GLN C 104      34.922   1.240  -8.332  1.00105.01           N
ATOM   2863  C   GLN C 104      30.002  -0.044  -8.466  1.00 95.90           C
ATOM   2864  O   GLN C 104      29.667  -1.206  -8.636  1.00 99.94           O
ATOM   2865  N   VAL C 105      29.120   0.930  -8.342  1.00 95.45           N
ATOM   2866  CA  VAL C 105      27.725   0.611  -8.146  1.00 92.37           C
ATOM   2867  CB  VAL C 105      27.521   0.420  -6.637  1.00 87.39           C
ATOM   2868  CG1 VAL C 105      26.963   1.708  -5.957  1.00 82.01           C
ATOM   2869  CG2 VAL C 105      26.735  -0.807  -6.372  1.00 80.78           C
ATOM   2870  C   VAL C 105      26.951   1.778  -8.752  1.00 96.54           C
ATOM   2871  O   VAL C 105      27.386   2.920  -8.626  1.00 93.03           O
ATOM   2872  N   LYS C 106      25.857   1.522  -9.472  1.00103.74           N
ATOM   2873  CA  LYS C 106      25.237   2.653 -10.194  1.00110.59           C
ATOM   2874  CB  LYS C 106      24.186   2.259 -11.260  1.00116.61           C
ATOM   2875  CG  LYS C 106      24.745   1.453 -12.499  1.00124.69           C
ATOM   2876  CD  LYS C 106      23.655   1.089 -13.580  1.00123.89           C
ATOM   2877  CE  LYS C 106      23.763  -0.421 -13.968  1.00129.73           C
ATOM   2878  NZ  LYS C 106      22.777  -0.880 -15.008  1.00128.80           N
ATOM   2879  C   LYS C 106      24.679   3.596  -9.160  1.00105.51           C
ATOM   2880  O   LYS C 106      25.036   4.765  -9.146  1.00105.06           O
ATOM   2881  N   ASN C 107      23.859   3.075  -8.253  1.00102.06           N
ATOM   2882  CA  ASN C 107      23.399   3.882  -7.136  1.00 98.48           C
ATOM   2883  CB  ASN C 107      21.925   4.240  -7.339  1.00 94.43           C
ATOM   2884  CG  ASN C 107      21.392   5.122  -6.259  1.00 95.00           C
ATOM   2885  OD1 ASN C 107      21.971   5.219  -5.184  1.00 99.19           O
ATOM   2886  ND2 ASN C 107      20.276   5.762  -6.517  1.00 93.85           N
ATOM   2887  C   ASN C 107      23.666   3.172  -5.788  1.00101.08           C
ATOM   2888  O   ASN C 107      23.013   2.160  -5.477  1.00103.04           O
ATOM   2889  N   TYR C 108      24.632   3.684  -5.004  1.00 99.32           N
ATOM   2890  CA  TYR C 108      24.993   3.075  -3.685  1.00 95.18           C
ATOM   2891  CB  TYR C 108      26.281   3.677  -3.090  1.00 88.94           C
ATOM   2892  CG  TYR C 108      26.128   5.016  -2.438  1.00 84.46           C
ATOM   2893  CD1 TYR C 108      26.258   6.182  -3.174  1.00 86.21           C
ATOM   2894  CE1 TYR C 108      26.142   7.456  -2.576  1.00 88.85           C
ATOM   2895  CZ  TYR C 108      25.876   7.574  -1.208  1.00 89.64           C
ATOM   2896  OH  TYR C 108      25.745   8.824  -0.623  1.00 88.11           O
ATOM   2897  CE2 TYR C 108      25.732   6.415  -0.453  1.00 90.30           C
ATOM   2898  CD2 TYR C 108      25.870   5.123  -1.095  1.00 86.05           C
ATOM   2899  C   TYR C 108      23.875   3.076  -2.618  1.00 93.58           C
ATOM   2900  O   TYR C 108      23.807   2.174  -1.756  1.00 93.55           O
ATOM   2901  N   ILE C 109      23.029   4.101  -2.659  1.00 86.77           N
ATOM   2902  CA  ILE C 109      21.898   4.104  -1.788  1.00 82.13           C
ATOM   2903  CB  ILE C 109      21.175   5.414  -1.793  1.00 75.34           C
ATOM   2904  CG1 ILE C 109      22.057   6.484  -1.214  1.00 73.01           C
ATOM   2905  CD1 ILE C 109      22.300   6.318   0.216  1.00 76.50           C
ATOM   2906  CG2 ILE C 109      20.001   5.347  -0.895  1.00 72.37           C
ATOM   2907  C   ILE C 109      20.966   2.983  -2.198  1.00 84.82           C
ATOM   2908  O   ILE C 109      20.535   2.195  -1.337  1.00 86.70           O
ATOM   2909  N   MET C 110      20.672   2.874  -3.488  1.00 83.34           N
ATOM   2910  CA  MET C 110      19.880   1.738  -3.919  1.00 88.73           C
ATOM   2911  CB  MET C 110      19.691   1.722  -5.403  1.00 93.33           C
ATOM   2912  CG  MET C 110      18.253   1.792  -5.802  1.00101.76           C
ATOM   2913  SD  MET C 110      18.099   3.296  -6.751  1.00107.54           S
ATOM   2914  CE  MET C 110      17.452   4.435  -5.465  1.00104.47           C
ATOM   2915  C   MET C 110      20.468   0.413  -3.498  1.00 90.45           C
ATOM   2916  O   MET C 110      19.754  -0.412  -2.932  1.00 92.72           O
ATOM   2917  N   ALA C 111      21.770   0.222  -3.751  1.00 90.89           N
ATOM   2918  CA  ALA C 111      22.431  -1.079  -3.524  1.00 84.88           C
ATOM   2919  CB  ALA C 111      23.814  -1.123  -4.142  1.00 81.33           C
ATOM   2920  C   ALA C 111      22.459  -1.450  -2.051  1.00 79.25           C
ATOM   2921  O   ALA C 111      22.113  -2.587  -1.693  1.00 78.90           O
ATOM   2922  N   THR C 112      22.825  -0.495  -1.202  1.00 73.10           N
ATOM   2923  CA  THR C 112      22.603  -0.671   0.233  1.00 73.44           C
ATOM   2924  CB  THR C 112      23.045   0.543   1.041  1.00 72.12           C
ATOM   2925  OG1 THR C 112      24.359   0.927   0.617  1.00 74.72           O
ATOM   2926  CG2 THR C 112      23.022   0.254   2.552  1.00 64.71           C
ATOM   2927  C   THR C 112      21.145  -1.077   0.569  1.00 77.19           C
ATOM   2928  O   THR C 112      20.940  -2.068   1.284  1.00 79.42           O
ATOM   2929  N   SER C 113      20.137  -0.374   0.036  1.00 77.87           N
ATOM   2930  CA  SER C 113      18.760  -0.814   0.229  1.00 75.28           C
ATOM   2931  CB  SER C 113      17.837   0.015  -0.581  1.00 69.28           C
ATOM   2932  OG  SER C 113      16.655   0.089   0.152  1.00 74.54           O
ATOM   2933  C   SER C 113      18.545  -2.303  -0.137  1.00 79.84           C
ATOM   2934  O   SER C 113      18.008  -3.100   0.624  1.00 81.03           O
ATOM   2935  N   GLN C 114      19.017  -2.719  -1.286  1.00 83.66           N
ATOM   2936  CA  GLN C 114      18.787  -4.096  -1.641  1.00 86.47           C
ATOM   2937  CB  GLN C 114      18.873  -4.261  -3.151  1.00 91.94           C
ATOM   2938  CG  GLN C 114      18.449  -5.633  -3.585  1.00101.34           C
ATOM   2939  CD  GLN C 114      17.118  -5.621  -4.235  1.00107.71           C
ATOM   2940  OE1 GLN C 114      16.943  -5.011  -5.314  1.00112.18           O
ATOM   2941  NE2 GLN C 114      16.151  -6.293  -3.603  1.00108.32           N
ATOM   2942  C   GLN C 114      19.633  -5.163  -0.864  1.00 84.74           C
ATOM   2943  O   GLN C 114      19.107  -6.230  -0.518  1.00 76.70           O
ATOM   2944  N   ILE C 115      20.922  -4.942  -0.596  1.00 84.35           N
ATOM   2945  CA  ILE C 115      21.545  -6.021   0.155  1.00 85.70           C
ATOM   2946  CB  ILE C 115      23.065  -5.979   0.352  1.00 82.91           C
ATOM   2947  CG1 ILE C 115      23.573  -4.625   0.050  1.00 83.50           C
ATOM   2948  CD1 ILE C 115      23.812  -3.904   1.361  1.00 89.29           C
ATOM   2949  CG2 ILE C 115      23.779  -7.109  -0.330  1.00 79.41           C
ATOM   2950  C   ILE C 115      20.881  -6.036   1.509  1.00 84.33           C
ATOM   2951  O   ILE C 115      20.566  -7.119   2.010  1.00 87.66           O
ATOM   2952  N   SER C 116      20.649  -4.858   2.085  1.00 75.97           N
ATOM   2953  CA  SER C 116      19.926  -4.805   3.338  1.00 75.42           C
ATOM   2954  CB  SER C 116      19.680  -3.368   3.737  1.00 70.11           C
ATOM   2955  OG  SER C 116      20.894  -2.786   4.128  1.00 69.88           O
ATOM   2956  C   SER C 116      18.580  -5.586   3.260  1.00 79.66           C
ATOM   2957  O   SER C 116      18.258  -6.419   4.154  1.00 76.14           O
ATOM   2958  N   GLN C 117      17.811  -5.346   2.190  1.00 78.05           N
ATOM   2959  CA  GLN C 117      16.525  -6.028   2.038  1.00 79.84           C
ATOM   2960  CB  GLN C 117      15.775  -5.530   0.791  1.00 78.68           C
ATOM   2961  CG  GLN C 117      15.052  -4.189   1.024  1.00 79.08           C
ATOM   2962  CD  GLN C 117      14.699  -3.506  -0.267  1.00 78.99           C
ATOM   2963  OE1 GLN C 117      13.931  -4.066  -1.023  1.00 84.53           O
ATOM   2964  NE2 GLN C 117      15.262  -2.303  -0.545  1.00 70.47           N
ATOM   2965  C   GLN C 117      16.687  -7.556   2.053  1.00 82.57           C
ATOM   2966  O   GLN C 117      16.048  -8.262   2.833  1.00 86.11           O
ATOM   2967  N   THR C 118      17.603  -8.028   1.219  1.00 84.79           N
ATOM   2968  CA  THR C 118      17.865  -9.429   0.976  1.00 81.04           C
ATOM   2969  CB  THR C 118      18.832  -9.525  -0.197  1.00 82.92           C
ATOM   2970  OG1 THR C 118      18.196  -8.958  -1.335  1.00 90.75           O
ATOM   2971  CG2 THR C 118      19.134 -10.905  -0.543  1.00 84.53           C
ATOM   2972  C   THR C 118      18.461 -10.087   2.192  1.00 76.79           C
ATOM   2973  O   THR C 118      18.168 -11.242   2.483  1.00 77.99           O
ATOM   2974  N   THR C 119      19.310  -9.354   2.893  1.00 76.53           N
ATOM   2975  CA  THR C 119      19.999  -9.897   4.051  1.00 79.29           C
ATOM   2976  CB  THR C 119      21.059  -8.938   4.579  1.00 79.40           C
ATOM   2977  OG1 THR C 119      22.071  -8.748   3.585  1.00 79.46           O
ATOM   2978  CG2 THR C 119      21.668  -9.481   5.833  1.00 78.47           C
ATOM   2979  C   THR C 119      18.979 -10.124   5.137  1.00 81.22           C
ATOM   2980  O   THR C 119      18.917 -11.203   5.723  1.00 82.98           O
ATOM   2981  N   LEU C 120      18.168  -9.095   5.373  1.00 83.16           N
ATOM   2982  CA  LEU C 120      17.080  -9.149   6.349  1.00 83.60           C
ATOM   2983  CB  LEU C 120      16.310  -7.806   6.409  1.00 80.93           C
ATOM   2984  CG  LEU C 120      15.168  -7.658   7.422  1.00 79.07           C
ATOM   2985  CD1 LEU C 120      15.628  -7.652   8.883  1.00 74.96           C
ATOM   2986  CD2 LEU C 120      14.349  -6.433   7.118  1.00 79.63           C
ATOM   2987  C   LEU C 120      16.152 -10.314   6.036  1.00 83.04           C
ATOM   2988  O   LEU C 120      15.790 -11.066   6.933  1.00 83.48           O
ATOM   2989  N   ARG C 121      15.795 -10.483   4.769  1.00 86.57           N
ATOM   2990  CA  ARG C 121      14.811 -11.499   4.435  1.00 97.60           C
ATOM   2991  CB  ARG C 121      14.340 -11.443   2.964  1.00 98.19           C
ATOM   2992  CG  ARG C 121      12.891 -11.926   2.774  1.00107.02           C
ATOM   2993  CD  ARG C 121      12.485 -12.249   1.333  1.00113.74           C
ATOM   2994  NE  ARG C 121      12.714 -11.104   0.438  1.00131.46           N
ATOM   2995  CZ  ARG C 121      13.735 -10.984  -0.437  1.00137.01           C
ATOM   2996  NH1 ARG C 121      14.649 -11.962  -0.560  1.00137.63           N
ATOM   2997  NH2 ARG C 121      13.845  -9.883  -1.205  1.00136.45           N
ATOM   2998  C   ARG C 121      15.397 -12.848   4.812  1.00 96.09           C
ATOM   2999  O   ARG C 121      14.707 -13.681   5.411  1.00 98.14           O
ATOM   3000  N   SER C 122      16.678 -13.034   4.502  1.00 94.38           N
ATOM   3001  CA  SER C 122      17.346 -14.281   4.793  1.00 96.89           C
ATOM   3002  CB  SER C 122      18.734 -14.290   4.192  1.00101.22           C
ATOM   3003  OG  SER C 122      18.718 -15.106   3.037  1.00110.03           O
ATOM   3004  C   SER C 122      17.432 -14.546   6.275  1.00 95.02           C
ATOM   3005  O   SER C 122      17.079 -15.622   6.748  1.00 97.79           O
ATOM   3006  N   VAL C 123      17.887 -13.539   6.995  1.00 90.46           N
ATOM   3007  CA  VAL C 123      18.088 -13.614   8.420  1.00 86.28           C
ATOM   3008  CB  VAL C 123      18.710 -12.313   8.915  1.00 81.62           C
ATOM   3009  CG1 VAL C 123      18.687 -12.237  10.392  1.00 80.87           C
ATOM   3010  CG2 VAL C 123      20.108 -12.223   8.420  1.00 78.17           C
ATOM   3011  C   VAL C 123      16.778 -13.875   9.142  1.00 87.76           C
ATOM   3012  O   VAL C 123      16.747 -14.478  10.207  1.00 93.58           O
ATOM   3013  N   ILE C 124      15.683 -13.431   8.582  1.00 87.21           N
ATOM   3014  CA  ILE C 124      14.452 -13.638   9.289  1.00 91.02           C
ATOM   3015  CB  ILE C 124      13.366 -12.653   8.829  1.00 94.54           C
ATOM   3016  CG1 ILE C 124      13.680 -11.276   9.395  1.00 95.36           C
ATOM   3017  CD1 ILE C 124      12.852 -10.225   8.772  1.00 95.95           C
ATOM   3018  CG2 ILE C 124      11.964 -13.093   9.293  1.00 94.77           C
ATOM   3019  C   ILE C 124      14.027 -15.071   9.106  1.00 89.66           C
ATOM   3020  O   ILE C 124      13.525 -15.683  10.030  1.00 86.93           O
ATOM   3021  N   GLY C 125      14.252 -15.589   7.902  1.00 94.16           N
ATOM   3022  CA  GLY C 125      13.859 -16.939   7.523  1.00 98.39           C
ATOM   3023  C   GLY C 125      14.604 -17.914   8.401  1.00104.44           C
ATOM   3024  O   GLY C 125      14.115 -19.001   8.659  1.00107.55           O
ATOM   3025  N   GLN C 126      15.773 -17.502   8.894  1.00107.05           N
ATOM   3026  CA  GLN C 126      16.588 -18.328   9.779  1.00108.71           C
ATOM   3027  CB  GLN C 126      18.051 -17.903   9.748  1.00116.48           C
ATOM   3028  CG  GLN C 126      18.838 -18.471   8.584  1.00124.96           C
ATOM   3029  CD  GLN C 126      18.564 -19.931   8.351  1.00127.72           C
ATOM   3030  OE1 GLN C 126      18.714 -20.770   9.265  1.00133.63           O
ATOM   3031  NE2 GLN C 126      18.148 -20.253   7.126  1.00123.80           N
ATOM   3032  C   GLN C 126      16.220 -18.271  11.218  1.00107.65           C
ATOM   3033  O   GLN C 126      16.694 -19.116  11.975  1.00112.38           O
ATOM   3034  N   ALA C 127      15.456 -17.254  11.617  1.00102.49           N
ATOM   3035  CA  ALA C 127      15.240 -16.989  13.027  1.00 95.52           C
ATOM   3036  CB  ALA C 127      15.276 -15.592  13.268  1.00 95.99           C
ATOM   3037  C   ALA C 127      13.924 -17.505  13.431  1.00 96.70           C
ATOM   3038  O   ALA C 127      13.008 -17.563  12.615  1.00 97.61           O
ATOM   3039  N   HIS C 128      13.843 -17.919  14.696  1.00100.72           N
ATOM   3040  CA  HIS C 128      12.583 -18.436  15.298  1.00100.35           C
ATOM   3041  CB  HIS C 128      12.852 -19.326  16.537  1.00102.33           C
ATOM   3042  CG  HIS C 128      13.189 -20.752  16.233  1.00103.88           C
ATOM   3043  ND1 HIS C 128      12.230 -21.691  15.886  1.00104.75           N
ATOM   3044  CE1 HIS C 128      12.810 -22.864  15.704  1.00104.82           C
ATOM   3045  NE2 HIS C 128      14.109 -22.720  15.923  1.00108.11           N
ATOM   3046  CD2 HIS C 128      14.371 -21.414  16.275  1.00103.15           C
ATOM   3047  C   HIS C 128      11.788 -17.234  15.766  1.00 96.35           C
ATOM   3048  O   HIS C 128      12.357 -16.262  16.250  1.00 95.20           O
ATOM   3049  N   LEU C 129      10.476 -17.294  15.673  1.00 93.76           N
ATOM   3050  CA  LEU C 129       9.690 -16.171  16.165  1.00 93.45           C
ATOM   3051  CB  LEU C 129       8.215 -16.526  16.317  1.00 94.68           C
ATOM   3052  CG  LEU C 129       7.372 -15.395  16.903  1.00 95.24           C
ATOM   3053  CD1 LEU C 129       7.261 -14.206  15.956  1.00 94.55           C
ATOM   3054  CD2 LEU C 129       6.006 -15.935  17.291  1.00 96.19           C
ATOM   3055  C   LEU C 129      10.234 -15.611  17.473  1.00 91.10           C
ATOM   3056  O   LEU C 129      10.537 -14.423  17.577  1.00 91.54           O
ATOM   3057  N   ASP C 130      10.371 -16.439  18.487  1.00 92.39           N
ATOM   3058  CA  ASP C 130      10.781 -15.844  19.742  1.00 97.68           C
ATOM   3059  CB  ASP C 130      10.924 -16.870  20.865  1.00102.80           C
ATOM   3060  CG  ASP C 130      11.091 -16.197  22.220  1.00105.65           C
ATOM   3061  OD1 ASP C 130      12.244 -15.969  22.663  1.00103.11           O
ATOM   3062  OD2 ASP C 130      10.052 -15.832  22.802  1.00109.30           O
ATOM   3063  C   ASP C 130      12.050 -14.998  19.591  1.00 95.65           C
ATOM   3064  O   ASP C 130      12.254 -14.038  20.318  1.00 97.13           O
ATOM   3065  N   GLU C 131      12.880 -15.335  18.623  1.00 95.96           N
ATOM   3066  CA  GLU C 131      14.158 -14.653  18.481  1.00100.13           C
ATOM   3067  CB  GLU C 131      15.075 -15.363  17.471  1.00107.71           C
ATOM   3068  CG  GLU C 131      15.220 -16.850  17.709  1.00114.59           C
ATOM   3069  CD  GLU C 131      16.491 -17.426  17.128  1.00120.16           C
ATOM   3070  OE1 GLU C 131      16.378 -18.378  16.310  1.00122.76           O
ATOM   3071  OE2 GLU C 131      17.588 -16.939  17.512  1.00120.90           O
ATOM   3072  C   GLU C 131      13.977 -13.201  18.089  1.00 94.34           C
ATOM   3073  O   GLU C 131      14.637 -12.348  18.658  1.00 91.86           O
ATOM   3074  N   LEU C 132      13.105 -12.957  17.109  1.00 88.64           N
ATOM   3075  CA  LEU C 132      12.723 -11.635  16.689  1.00 88.92           C
ATOM   3076  CB  LEU C 132      11.555 -11.671  15.733  1.00 87.94           C
ATOM   3077  CG  LEU C 132      11.693 -12.114  14.303  1.00 89.23           C
ATOM   3078  CD1 LEU C 132      10.358 -11.852  13.654  1.00 86.46           C
ATOM   3079  CD2 LEU C 132      12.762 -11.290  13.649  1.00 93.24           C
ATOM   3080  C   LEU C 132      12.217 -10.826  17.839  1.00 93.70           C
ATOM   3081  O   LEU C 132      12.528  -9.643  17.904  1.00 98.38           O
ATOM   3082  N   LEU C 133      11.393 -11.432  18.710  1.00 94.33           N
ATOM   3083  CA  LEU C 133      10.738 -10.688  19.820  1.00 91.84           C
ATOM   3084  CB  LEU C 133       9.467 -11.383  20.315  1.00 87.63           C
ATOM   3085  CG  LEU C 133       8.436 -11.830  19.298  1.00 85.59           C
ATOM   3086  CD1 LEU C 133       7.455 -12.680  20.025  1.00 87.51           C
ATOM   3087  CD2 LEU C 133       7.756 -10.672  18.678  1.00 83.23           C
ATOM   3088  C   LEU C 133      11.660 -10.462  21.015  1.00 91.87           C
ATOM   3089  O   LEU C 133      11.695  -9.373  21.604  1.00 91.30           O
ATOM   3090  N   SER C 134      12.404 -11.497  21.370  1.00 93.97           N
ATOM   3091  CA  SER C 134      13.186 -11.458  22.583  1.00 99.35           C
ATOM   3092  CB  SER C 134      12.839 -12.652  23.455  1.00104.34           C
ATOM   3093  OG  SER C 134      11.447 -12.623  23.798  1.00106.64           O
ATOM   3094  C   SER C 134      14.679 -11.335  22.356  1.00 99.92           C
ATOM   3095  O   SER C 134      15.328 -10.617  23.070  1.00102.18           O
ATOM   3096  N   GLU C 135      15.232 -11.951  21.332  1.00100.26           N
ATOM   3097  CA  GLU C 135      16.637 -11.658  21.067  1.00103.48           C
ATOM   3098  CB  GLU C 135      17.342 -12.941  20.805  1.00108.41           C
ATOM   3099  CG  GLU C 135      17.089 -13.969  21.867  1.00109.59           C
ATOM   3100  CD  GLU C 135      18.159 -14.989  21.813  1.00104.40           C
ATOM   3101  OE1 GLU C 135      19.319 -14.578  22.060  1.00103.01           O
ATOM   3102  OE2 GLU C 135      17.826 -16.142  21.472  1.00100.11           O
ATOM   3103  C   GLU C 135      17.010 -10.652  19.966  1.00103.59           C
ATOM   3104  O   GLU C 135      18.068 -10.767  19.348  1.00 97.10           O
ATOM   3105  N   ARG C 136      16.171  -9.643  19.744  1.00107.01           N
ATOM   3106  CA  ARG C 136      16.451  -8.683  18.682  1.00106.61           C
ATOM   3107  CB  ARG C 136      15.525  -7.469  18.748  1.00105.74           C
ATOM   3108  CG  ARG C 136      14.450  -7.468  17.647  1.00110.35           C
ATOM   3109  CD  ARG C 136      13.185  -6.671  18.008  1.00114.85           C
ATOM   3110  NE  ARG C 136      13.502  -5.416  18.690  1.00125.15           N
ATOM   3111  CZ  ARG C 136      13.137  -4.205  18.260  1.00130.80           C
ATOM   3112  NH1 ARG C 136      12.401  -4.065  17.157  1.00134.47           N
ATOM   3113  NH2 ARG C 136      13.485  -3.126  18.955  1.00134.55           N
ATOM   3114  C   ARG C 136      17.928  -8.304  18.637  1.00103.15           C
ATOM   3115  O   ARG C 136      18.529  -8.272  17.567  1.00103.73           O
ATOM   3116  N   ASP C 137      18.538  -8.081  19.792  1.00102.38           N
ATOM   3117  CA  ASP C 137      19.903  -7.584  19.767  1.00103.30           C
ATOM   3118  CB  ASP C 137      20.457  -7.195  21.155  1.00106.60           C
ATOM   3119  CG  ASP C 137      21.665  -6.230  21.046  1.00108.24           C
ATOM   3120  OD1 ASP C 137      21.597  -5.315  20.188  1.00111.16           O
ATOM   3121  OD2 ASP C 137      22.681  -6.376  21.778  1.00107.48           O
ATOM   3122  C   ASP C 137      20.869  -8.487  18.986  1.00 99.71           C
ATOM   3123  O   ASP C 137      21.583  -8.013  18.116  1.00101.61           O
ATOM   3124  N   LYS C 138      20.879  -9.777  19.281  1.00 95.77           N
ATOM   3125  CA  LYS C 138      21.728 -10.713  18.557  1.00 89.10           C
ATOM   3126  CB  LYS C 138      21.454 -12.127  19.051  1.00 89.88           C
ATOM   3127  CG  LYS C 138      21.856 -13.234  18.158  1.00 96.68           C
ATOM   3128  CD  LYS C 138      21.144 -14.508  18.605  1.00101.97           C
ATOM   3129  CE  LYS C 138      20.980 -15.517  17.462  1.00107.35           C
ATOM   3130  NZ  LYS C 138      19.718 -16.284  17.719  1.00107.64           N
ATOM   3131  C   LYS C 138      21.530 -10.525  17.040  1.00 86.38           C
ATOM   3132  O   LYS C 138      22.509 -10.248  16.322  1.00 84.11           O
ATOM   3133  N   LEU C 139      20.275 -10.593  16.570  1.00 84.02           N
ATOM   3134  CA  LEU C 139      19.930 -10.390  15.138  1.00 82.07           C
ATOM   3135  CB  LEU C 139      18.398 -10.356  14.945  1.00 81.37           C
ATOM   3136  CG  LEU C 139      17.514 -11.583  15.213  1.00 81.27           C
ATOM   3137  CD1 LEU C 139      16.369 -11.560  14.298  1.00 78.49           C
ATOM   3138  CD2 LEU C 139      18.243 -12.851  14.936  1.00 86.05           C
ATOM   3139  C   LEU C 139      20.557  -9.102  14.545  1.00 82.93           C
ATOM   3140  O   LEU C 139      21.527  -9.123  13.704  1.00 73.14           O
ATOM   3141  N   ASN C 140      19.979  -7.984  15.002  1.00 83.15           N
ATOM   3142  CA  ASN C 140      20.607  -6.681  14.887  1.00 83.43           C
ATOM   3143  CB  ASN C 140      20.344  -5.924  16.150  1.00 80.37           C
ATOM   3144  CG  ASN C 140      19.114  -5.129  16.071  1.00 84.13           C
ATOM   3145  OD1 ASN C 140      18.416  -5.136  15.056  1.00 82.46           O
ATOM   3146  ND2 ASN C 140      18.826  -4.399  17.142  1.00 89.60           N
ATOM   3147  C   ASN C 140      22.112  -6.701  14.616  1.00 86.20           C
ATOM   3148  O   ASN C 140      22.576  -6.088  13.674  1.00 86.14           O
ATOM   3149  N   MET C 141      22.858  -7.440  15.434  1.00 90.65           N
ATOM   3150  CA  MET C 141      24.308  -7.446  15.345  1.00 94.36           C
ATOM   3151  CB  MET C 141      24.920  -7.857  16.681  1.00 93.80           C
ATOM   3152  CG  MET C 141      24.866  -6.736  17.706  1.00 95.86           C
ATOM   3153  SD  MET C 141      25.648  -7.140  19.299  1.00105.19           S
ATOM   3154  CE  MET C 141      25.229  -5.665  20.349  1.00 99.16           C
ATOM   3155  C   MET C 141      24.880  -8.220  14.130  1.00 90.09           C
ATOM   3156  O   MET C 141      25.814  -7.738  13.465  1.00 85.12           O
ATOM   3157  N   GLN C 142      24.309  -9.387  13.834  1.00 86.62           N
ATOM   3158  CA  GLN C 142      24.741 -10.181  12.675  1.00 84.79           C
ATOM   3159  CB  GLN C 142      24.120 -11.594  12.713  1.00 79.26           C
ATOM   3160  CG  GLN C 142      23.618 -12.167  11.410  1.00 77.43           C
ATOM   3161  CD  GLN C 142      23.579 -13.693  11.419  1.00 84.79           C
ATOM   3162  OE1 GLN C 142      22.535 -14.328  11.172  1.00 86.43           O
ATOM   3163  NE2 GLN C 142      24.737 -14.301  11.687  1.00 89.71           N
ATOM   3164  C   GLN C 142      24.334  -9.390  11.435  1.00 88.77           C
ATOM   3165  O   GLN C 142      25.058  -9.330  10.402  1.00 86.63           O
ATOM   3166  N   LEU C 143      23.176  -8.741  11.560  1.00 88.35           N
ATOM   3167  CA  LEU C 143      22.688  -7.945  10.463  1.00 84.98           C
ATOM   3168  CB  LEU C 143      21.364  -7.271  10.835  1.00 81.07           C
ATOM   3169  CG  LEU C 143      20.137  -8.129  10.526  1.00 76.08           C
ATOM   3170  CD1 LEU C 143      18.932  -7.479  11.115  1.00 75.05           C
ATOM   3171  CD2 LEU C 143      19.953  -8.268   9.038  1.00 72.38           C
ATOM   3172  C   LEU C 143      23.795  -6.959  10.063  1.00 83.29           C
ATOM   3173  O   LEU C 143      24.175  -6.872   8.891  1.00 82.38           O
ATOM   3174  N   GLN C 144      24.350  -6.277  11.062  1.00 77.95           N
ATOM   3175  CA  GLN C 144      25.395  -5.297  10.845  1.00 72.61           C
ATOM   3176  CB  GLN C 144      25.692  -4.645  12.170  1.00 73.59           C
ATOM   3177  CG  GLN C 144      26.698  -3.567  12.096  1.00 74.78           C
ATOM   3178  CD  GLN C 144      28.054  -4.097  11.868  1.00 70.53           C
ATOM   3179  OE1 GLN C 144      28.518  -4.989  12.559  1.00 74.86           O
ATOM   3180  NE2 GLN C 144      28.699  -3.565  10.892  1.00 69.18           N
ATOM   3181  C   GLN C 144      26.661  -5.903  10.224  1.00 69.20           C
ATOM   3182  O   GLN C 144      27.144  -5.441   9.219  1.00 69.28           O
ATOM   3183  N   ARG C 145      27.176  -6.950  10.839  1.00 70.82           N
ATOM   3184  CA  ARG C 145      28.251  -7.775  10.290  1.00 71.83           C
ATOM   3185  CB  ARG C 145      28.379  -9.062  11.125  1.00 71.68           C
ATOM   3186  CG  ARG C 145      29.117  -8.952  12.480  1.00 72.79           C
ATOM   3187  CD  ARG C 145      29.269 -10.334  13.133  1.00 74.93           C
ATOM   3188  NE  ARG C 145      28.332 -10.498  14.250  1.00 82.85           N
ATOM   3189  CZ  ARG C 145      27.482 -11.518  14.413  1.00 82.27           C
ATOM   3190  NH1 ARG C 145      27.421 -12.523  13.553  1.00 81.99           N
ATOM   3191  NH2 ARG C 145      26.693 -11.543  15.473  1.00 81.97           N
ATOM   3192  C   ARG C 145      28.025  -8.158   8.805  1.00 75.48           C
ATOM   3193  O   ARG C 145      28.825  -7.795   7.896  1.00 79.41           O
ATOM   3194  N   ILE C 146      26.944  -8.882   8.538  1.00 69.13           N
ATOM   3195  CA  ILE C 146      26.736  -9.341   7.179  1.00 70.04           C
ATOM   3196  CB  ILE C 146      25.524 -10.274   7.099  1.00 68.65           C
ATOM   3197  CG1 ILE C 146      25.791 -11.511   7.976  1.00 69.63           C
ATOM   3198  CD1 ILE C 146      24.653 -12.471   8.067  1.00 71.70           C
ATOM   3199  CG2 ILE C 146      25.109 -10.585   5.620  1.00 59.57           C
ATOM   3200  C   ILE C 146      26.576  -8.168   6.213  1.00 76.05           C
ATOM   3201  O   ILE C 146      26.984  -8.217   5.059  1.00 79.53           O
ATOM   3202  N   ILE C 147      25.974  -7.088   6.668  1.00 82.85           N
ATOM   3203  CA  ILE C 147      25.665  -6.055   5.699  1.00 84.79           C
ATOM   3204  CB  ILE C 147      24.387  -5.198   6.051  1.00 85.13           C
ATOM   3205  CG1 ILE C 147      23.126  -6.025   5.718  1.00 81.41           C
ATOM   3206  CD1 ILE C 147      21.900  -5.532   6.459  1.00 85.85           C
ATOM   3207  CG2 ILE C 147      24.406  -3.764   5.354  1.00 79.67           C
ATOM   3208  C   ILE C 147      26.920  -5.268   5.432  1.00 83.75           C
ATOM   3209  O   ILE C 147      27.230  -5.019   4.256  1.00 81.92           O
ATOM   3210  N   ASP C 148      27.659  -4.933   6.500  1.00 81.93           N
ATOM   3211  CA  ASP C 148      28.756  -3.962   6.364  1.00 84.75           C
ATOM   3212  CB  ASP C 148      29.401  -3.661   7.689  1.00 79.37           C
ATOM   3213  CG  ASP C 148      30.490  -2.659   7.544  1.00 84.46           C
ATOM   3214  OD1 ASP C 148      30.533  -1.902   6.509  1.00 86.25           O
ATOM   3215  OD2 ASP C 148      31.330  -2.645   8.460  1.00 87.36           O
ATOM   3216  C   ASP C 148      29.842  -4.444   5.384  1.00 88.61           C
ATOM   3217  O   ASP C 148      30.406  -3.658   4.560  1.00 82.79           O
ATOM   3218  N   GLU C 149      30.129  -5.743   5.568  1.00 87.72           N
ATOM   3219  CA  GLU C 149      30.833  -6.609   4.668  1.00 81.19           C
ATOM   3220  CB  GLU C 149      30.594  -8.022   5.161  1.00 85.09           C
ATOM   3221  CG  GLU C 149      31.358  -9.092   4.429  1.00 94.95           C
ATOM   3222  CD  GLU C 149      32.876  -8.952   4.525  1.00101.65           C
ATOM   3223  OE1 GLU C 149      33.400  -8.350   5.502  1.00103.73           O
ATOM   3224  OE2 GLU C 149      33.541  -9.462   3.594  1.00105.17           O
ATOM   3225  C   GLU C 149      30.304  -6.437   3.259  1.00 80.41           C
ATOM   3226  O   GLU C 149      30.938  -5.768   2.458  1.00 79.67           O
ATOM   3227  N   ALA C 150      29.132  -7.011   2.960  1.00 83.56           N
ATOM   3228  CA  ALA C 150      28.537  -6.970   1.598  1.00 86.72           C
ATOM   3229  CB  ALA C 150      27.073  -7.260   1.665  1.00 86.42           C
ATOM   3230  C   ALA C 150      28.754  -5.617   0.951  1.00 87.76           C
ATOM   3231  O   ALA C 150      29.192  -5.498  -0.164  1.00 91.36           O
ATOM   3232  N   THR C 151      28.417  -4.608   1.717  1.00 87.85           N
ATOM   3233  CA  THR C 151      28.691  -3.235   1.477  1.00 89.75           C
ATOM   3234  CB  THR C 151      28.315  -2.528   2.803  1.00 89.23           C
ATOM   3235  OG1 THR C 151      27.010  -1.978   2.674  1.00 89.88           O
ATOM   3236  CG2 THR C 151      29.318  -1.477   3.236  1.00 90.28           C
ATOM   3237  C   THR C 151      30.121  -2.815   1.042  1.00 94.84           C
ATOM   3238  O   THR C 151      30.269  -1.768   0.419  1.00 98.95           O
ATOM   3239  N   ASP C 152      31.177  -3.549   1.403  1.00 96.96           N
ATOM   3240  CA  ASP C 152      32.519  -2.909   1.402  1.00 94.21           C
ATOM   3241  CB  ASP C 152      33.578  -3.680   2.193  1.00 93.22           C
ATOM   3242  CG  ASP C 152      33.631  -3.280   3.646  1.00 97.42           C
ATOM   3243  OD1 ASP C 152      32.777  -2.474   4.124  1.00101.21           O
ATOM   3244  OD2 ASP C 152      34.529  -3.807   4.330  1.00 97.07           O
ATOM   3245  C   ASP C 152      33.035  -2.561   0.013  1.00 94.12           C
ATOM   3246  O   ASP C 152      33.604  -1.459  -0.184  1.00 96.26           O
ATOM   3247  N   PRO C 153      32.837  -3.469  -0.964  1.00 88.54           N
ATOM   3248  CA  PRO C 153      33.210  -3.069  -2.323  1.00 87.83           C
ATOM   3249  CB  PRO C 153      32.440  -4.062  -3.189  1.00 86.47           C
ATOM   3250  CG  PRO C 153      32.475  -5.317  -2.373  1.00 86.62           C
ATOM   3251  CD  PRO C 153      32.298  -4.839  -0.925  1.00 85.72           C
ATOM   3252  C   PRO C 153      32.850  -1.591  -2.664  1.00 89.61           C
ATOM   3253  O   PRO C 153      33.736  -0.864  -3.144  1.00 93.00           O
ATOM   3254  N   TRP C 154      31.601  -1.168  -2.365  1.00 86.94           N
ATOM   3255  CA  TRP C 154      31.069   0.213  -2.567  1.00 83.85           C
ATOM   3256  CB  TRP C 154      29.535   0.250  -2.535  1.00 77.19           C
ATOM   3257  CG  TRP C 154      28.970  -0.927  -3.137  1.00 77.55           C
ATOM   3258  CD1 TRP C 154      29.439  -1.554  -4.216  1.00 80.33           C
ATOM   3259  NE1 TRP C 154      28.679  -2.676  -4.503  1.00 84.41           N
ATOM   3260  CE2 TRP C 154      27.681  -2.783  -3.583  1.00 81.24           C
ATOM   3261  CD2 TRP C 154      27.825  -1.690  -2.693  1.00 82.62           C
ATOM   3262  CE3 TRP C 154      26.904  -1.556  -1.637  1.00 83.41           C
ATOM   3263  CZ3 TRP C 154      25.896  -2.502  -1.528  1.00 80.28           C
ATOM   3264  CH2 TRP C 154      25.791  -3.570  -2.442  1.00 77.75           C
ATOM   3265  CZ2 TRP C 154      26.673  -3.725  -3.465  1.00 78.69           C
ATOM   3266  C   TRP C 154      31.630   1.302  -1.644  1.00 85.09           C
ATOM   3267  O   TRP C 154      31.274   2.471  -1.782  1.00 86.49           O
ATOM   3268  N   GLY C 155      32.523   0.954  -0.730  1.00 82.22           N
ATOM   3269  CA  GLY C 155      33.170   2.010   0.033  1.00 84.38           C
ATOM   3270  C   GLY C 155      32.254   2.581   1.090  1.00 84.54           C
ATOM   3271  O   GLY C 155      32.306   3.778   1.380  1.00 82.70           O
ATOM   3272  N   ILE C 156      31.433   1.709   1.679  1.00 84.74           N
ATOM   3273  CA  ILE C 156      30.563   2.136   2.761  1.00 87.01           C
ATOM   3274  CB  ILE C 156      29.050   2.033   2.357  1.00 85.64           C
ATOM   3275  CG1 ILE C 156      28.692   3.178   1.438  1.00 84.92           C
ATOM   3276  CD1 ILE C 156      28.726   2.737   0.064  1.00 87.76           C
ATOM   3277  CG2 ILE C 156      28.129   2.130   3.532  1.00 79.81           C
ATOM   3278  C   ILE C 156      30.840   1.428   4.079  1.00 87.25           C
ATOM   3279  O   ILE C 156      31.065   0.193   4.109  1.00 86.56           O
ATOM   3280  N   LYS C 157      30.810   2.214   5.162  1.00 87.73           N
ATOM   3281  CA  LYS C 157      30.785   1.650   6.513  1.00 90.91           C
ATOM   3282  CB  LYS C 157      31.763   2.348   7.490  1.00 98.74           C
ATOM   3283  CG  LYS C 157      32.099   1.423   8.704  1.00105.53           C
ATOM   3284  CD  LYS C 157      33.576   1.424   9.148  1.00109.66           C
ATOM   3285  CE  LYS C 157      33.751   0.697  10.528  1.00110.26           C
ATOM   3286  NZ  LYS C 157      34.879   1.227  11.448  1.00110.75           N
ATOM   3287  C   LYS C 157      29.359   1.627   7.062  1.00 87.65           C
ATOM   3288  O   LYS C 157      28.745   2.667   7.262  1.00 88.43           O
ATOM   3289  N   VAL C 158      28.826   0.430   7.272  1.00 81.66           N
ATOM   3290  CA  VAL C 158      27.536   0.282   7.898  1.00 77.75           C
ATOM   3291  CB  VAL C 158      26.799  -0.960   7.370  1.00 79.81           C
ATOM   3292  CG1 VAL C 158      25.533  -1.166   8.117  1.00 81.49           C
ATOM   3293  CG2 VAL C 158      26.508  -0.859   5.879  1.00 78.54           C
ATOM   3294  C   VAL C 158      27.880   0.086   9.360  1.00 77.50           C
ATOM   3295  O   VAL C 158      28.610  -0.824   9.716  1.00 75.31           O
ATOM   3296  N   THR C 159      27.346   0.944  10.207  1.00 78.40           N
ATOM   3297  CA  THR C 159      27.760   1.069  11.589  1.00 77.61           C
ATOM   3298  CB  THR C 159      27.705   2.533  11.882  1.00 76.55           C
ATOM   3299  OG1 THR C 159      28.993   3.013  11.629  1.00 78.13           O
ATOM   3300  CG2 THR C 159      27.262   2.933  13.318  1.00 80.08           C
ATOM   3301  C   THR C 159      26.870   0.244  12.511  1.00 85.09           C
ATOM   3302  O   THR C 159      27.355  -0.428  13.409  1.00 87.95           O
ATOM   3303  N   ALA C 160      25.560   0.281  12.270  1.00 85.29           N
ATOM   3304  CA  ALA C 160      24.598  -0.497  13.025  1.00 82.02           C
ATOM   3305  CB  ALA C 160      24.044   0.342  14.109  1.00 79.59           C
ATOM   3306  C   ALA C 160      23.512  -0.884  12.023  1.00 84.84           C
ATOM   3307  O   ALA C 160      23.520  -0.378  10.899  1.00 91.12           O
ATOM   3308  N   VAL C 161      22.605  -1.786  12.391  1.00 82.12           N
ATOM   3309  CA  VAL C 161      21.421  -2.108  11.572  1.00 78.03           C
ATOM   3310  CB  VAL C 161      21.662  -3.242  10.568  1.00 74.93           C
ATOM   3311  CG1 VAL C 161      20.345  -3.728   9.995  1.00 75.48           C
ATOM   3312  CG2 VAL C 161      22.559  -2.805   9.454  1.00 73.55           C
ATOM   3313  C   VAL C 161      20.419  -2.595  12.574  1.00 82.40           C
ATOM   3314  O   VAL C 161      20.667  -3.570  13.262  1.00 88.88           O
ATOM   3315  N   GLU C 162      19.299  -1.909  12.719  1.00 87.36           N
ATOM   3316  CA  GLU C 162      18.434  -2.194  13.863  1.00 85.92           C
ATOM   3317  CB  GLU C 162      18.456  -1.040  14.849  1.00 87.64           C
ATOM   3318  CG  GLU C 162      19.779  -0.892  15.583  1.00 94.21           C
ATOM   3319  CD  GLU C 162      19.689   0.115  16.733  1.00100.47           C
ATOM   3320  OE1 GLU C 162      18.612   0.772  16.846  1.00101.35           O
ATOM   3321  OE2 GLU C 162      20.680   0.232  17.521  1.00101.62           O
ATOM   3322  C   GLU C 162      17.041  -2.455  13.389  1.00 84.14           C
ATOM   3323  O   GLU C 162      16.408  -1.578  12.818  1.00 82.71           O
ATOM   3324  N   ILE C 163      16.592  -3.687  13.589  1.00 82.48           N
ATOM   3325  CA  ILE C 163      15.230  -4.073  13.288  1.00 82.98           C
ATOM   3326  CB  ILE C 163      14.968  -5.499  13.770  1.00 82.81           C
ATOM   3327  CG1 ILE C 163      15.850  -6.486  12.994  1.00 86.25           C
ATOM   3328  CD1 ILE C 163      15.579  -7.963  13.301  1.00 87.09           C
ATOM   3329  CG2 ILE C 163      13.497  -5.846  13.652  1.00 81.51           C
ATOM   3330  C   ILE C 163      14.296  -3.103  14.007  1.00 85.98           C
ATOM   3331  O   ILE C 163      14.475  -2.801  15.201  1.00 88.35           O
ATOM   3332  N   LYS C 164      13.297  -2.626  13.277  1.00 87.49           N
ATOM   3333  CA  LYS C 164      12.404  -1.568  13.744  1.00 89.56           C
ATOM   3334  CB  LYS C 164      12.220  -0.550  12.615  1.00 90.74           C
ATOM   3335  CG  LYS C 164      11.975   0.837  13.084  1.00 97.73           C
ATOM   3336  CD  LYS C 164      11.488   1.674  11.932  1.00102.10           C
ATOM   3337  CE  LYS C 164      10.572   2.785  12.400  1.00103.64           C
ATOM   3338  NZ  LYS C 164      10.213   3.510  11.175  1.00103.80           N
ATOM   3339  C   LYS C 164      11.039  -2.073  14.330  1.00 88.32           C
ATOM   3340  O   LYS C 164      10.859  -2.053  15.565  1.00 91.08           O
ATOM   3341  N   ASP C 165      10.103  -2.496  13.460  1.00 84.89           N
ATOM   3342  CA  ASP C 165       8.793  -3.035  13.844  1.00 83.97           C
ATOM   3343  CB  ASP C 165       7.590  -2.275  13.247  1.00 92.55           C
ATOM   3344  CG  ASP C 165       7.733  -0.752  13.284  1.00103.75           C
ATOM   3345  OD1 ASP C 165       7.768  -0.137  14.399  1.00106.08           O
ATOM   3346  OD2 ASP C 165       7.777  -0.163  12.164  1.00108.89           O
ATOM   3347  C   ASP C 165       8.705  -4.413  13.275  1.00 82.82           C
ATOM   3348  O   ASP C 165       9.026  -4.646  12.103  1.00 82.32           O
ATOM   3349  N   VAL C 166       8.222  -5.324  14.102  1.00 83.78           N
ATOM   3350  CA  VAL C 166       7.840  -6.650  13.662  1.00 83.36           C
ATOM   3351  CB  VAL C 166       8.408  -7.688  14.600  1.00 81.79           C
ATOM   3352  CG1 VAL C 166       7.498  -8.897  14.652  1.00 80.60           C
ATOM   3353  CG2 VAL C 166       9.788  -8.070  14.173  1.00 83.09           C
ATOM   3354  C   VAL C 166       6.326  -6.739  13.752  1.00 85.28           C
ATOM   3355  O   VAL C 166       5.779  -6.511  14.808  1.00 92.92           O
ATOM   3356  N   GLU C 167       5.652  -7.032  12.653  1.00 83.36           N
ATOM   3357  CA  GLU C 167       4.227  -7.195  12.662  1.00 86.09           C
ATOM   3358  CB  GLU C 167       3.584  -6.575  11.406  1.00 87.87           C
ATOM   3359  CG  GLU C 167       3.748  -5.046  11.236  1.00 95.99           C
ATOM   3360  CD  GLU C 167       2.990  -4.488  10.021  1.00 99.91           C
ATOM   3361  OE1 GLU C 167       3.522  -4.505   8.876  1.00108.19           O
ATOM   3362  OE2 GLU C 167       1.848  -4.015  10.207  1.00104.83           O
ATOM   3363  C   GLU C 167       3.973  -8.695  12.686  1.00 88.03           C
ATOM   3364  O   GLU C 167       4.454  -9.466  11.798  1.00 91.98           O
ATOM   3365  N   LEU C 168       3.232  -9.116  13.708  1.00 84.65           N
ATOM   3366  CA  LEU C 168       2.650 -10.448  13.749  1.00 81.14           C
ATOM   3367  CB  LEU C 168       2.373 -10.742  15.174  1.00 82.62           C
ATOM   3368  CG  LEU C 168       3.715 -11.071  15.702  1.00 86.31           C
ATOM   3369  CD1 LEU C 168       3.586 -11.388  17.178  1.00 88.37           C
ATOM   3370  CD2 LEU C 168       4.145 -12.252  14.868  1.00 87.28           C
ATOM   3371  C   LEU C 168       1.317 -10.490  13.035  1.00 84.97           C
ATOM   3372  O   LEU C 168       0.685  -9.438  12.868  1.00 85.84           O
ATOM   3373  N   PRO C 169       0.846 -11.693  12.641  1.00 85.22           N
ATOM   3374  CA  PRO C 169      -0.535 -11.830  12.191  1.00 84.86           C
ATOM   3375  CB  PRO C 169      -0.634 -13.286  11.768  1.00 81.89           C
ATOM   3376  CG  PRO C 169       0.450 -13.946  12.344  1.00 83.71           C
ATOM   3377  CD  PRO C 169       1.550 -12.974  12.604  1.00 86.30           C
ATOM   3378  C   PRO C 169      -1.462 -11.532  13.355  1.00 90.96           C
ATOM   3379  O   PRO C 169      -1.195 -11.961  14.493  1.00 92.24           O
ATOM   3380  N   ALA C 170      -2.508 -10.742  13.096  1.00 96.10           N
ATOM   3381  CA  ALA C 170      -3.285 -10.127  14.206  1.00 98.55           C
ATOM   3382  CB  ALA C 170      -4.177  -8.971  13.719  1.00 92.12           C
ATOM   3383  C   ALA C 170      -4.064 -11.135  15.065  1.00 99.07           C
ATOM   3384  O   ALA C 170      -4.334 -12.265  14.651  1.00101.91           O
ATOM   3385  N   GLY C 171      -4.356 -10.752  16.290  1.00 97.40           N
ATOM   3386  CA  GLY C 171      -4.935 -11.693  17.195  1.00 95.81           C
ATOM   3387  C   GLY C 171      -3.958 -12.655  17.830  1.00 93.58           C
ATOM   3388  O   GLY C 171      -4.156 -13.082  18.973  1.00 98.05           O
ATOM   3389  N   MET C 172      -2.909 -13.018  17.113  1.00 95.08           N
ATOM   3390  CA  MET C 172      -1.921 -13.984  17.650  1.00 95.43           C
ATOM   3391  CB  MET C 172      -0.834 -14.244  16.618  1.00 90.97           C
ATOM   3392  CG  MET C 172       0.350 -14.896  17.146  1.00 88.42           C
ATOM   3393  SD  MET C 172       1.134 -15.656  15.737  1.00 95.25           S
ATOM   3394  CE  MET C 172       2.429 -16.579  16.600  1.00 91.11           C
ATOM   3395  C   MET C 172      -1.295 -13.507  18.964  1.00 96.45           C
ATOM   3396  O   MET C 172      -1.103 -14.281  19.909  1.00 94.84           O
ATOM   3397  N   GLN C 173      -1.024 -12.209  19.019  1.00 97.10           N
ATOM   3398  CA  GLN C 173      -0.305 -11.628  20.125  1.00 96.87           C
ATOM   3399  CB  GLN C 173       0.240 -10.292  19.657  1.00 96.98           C
ATOM   3400  CG  GLN C 173       0.553  -9.398  20.804  1.00 95.80           C
ATOM   3401  CD  GLN C 173       1.601  -8.464  20.456  1.00 94.06           C
ATOM   3402  OE1 GLN C 173       2.775  -8.609  20.924  1.00 92.54           O
ATOM   3403  NE2 GLN C 173       1.239  -7.494  19.587  1.00 87.24           N
ATOM   3404  C   GLN C 173      -1.136 -11.462  21.423  1.00 97.41           C
ATOM   3405  O   GLN C 173      -0.614 -11.626  22.550  1.00 89.87           O
ATOM   3406  N   LYS C 174      -2.405 -11.083  21.247  1.00100.52           N
ATOM   3407  CA  LYS C 174      -3.388 -11.073  22.337  1.00105.50           C
ATOM   3408  CB  LYS C 174      -4.769 -10.664  21.810  1.00111.65           C
ATOM   3409  CG  LYS C 174      -5.587  -9.668  22.716  1.00115.29           C
ATOM   3410  CD  LYS C 174      -6.837  -9.074  21.922  1.00114.85           C
ATOM   3411  CE  LYS C 174      -6.479  -8.240  20.608  1.00114.25           C
ATOM   3412  NZ  LYS C 174      -6.207  -6.792  20.848  1.00105.31           N
ATOM   3413  C   LYS C 174      -3.483 -12.483  22.932  1.00101.36           C
ATOM   3414  O   LYS C 174      -3.388 -12.638  24.145  1.00 99.84           O
ATOM   3415  N   ALA C 175      -3.668 -13.493  22.072  1.00 96.01           N
ATOM   3416  CA  ALA C 175      -3.621 -14.898  22.472  1.00 92.54           C
ATOM   3417  CB  ALA C 175      -3.555 -15.780  21.251  1.00 95.76           C
ATOM   3418  C   ALA C 175      -2.448 -15.202  23.405  1.00 92.16           C
ATOM   3419  O   ALA C 175      -2.637 -15.625  24.541  1.00 91.68           O
ATOM   3420  N   MET C 176      -1.234 -14.976  22.927  1.00 92.58           N
ATOM   3421  CA  MET C 176      -0.042 -15.208  23.741  1.00 95.75           C
ATOM   3422  CB  MET C 176       1.213 -14.900  22.944  1.00 96.65           C
ATOM   3423  CG  MET C 176       1.147 -15.266  21.489  1.00 99.54           C
ATOM   3424  SD  MET C 176       2.689 -14.943  20.601  1.00101.41           S
ATOM   3425  CE  MET C 176       3.879 -15.854  21.631  1.00100.61           C
ATOM   3426  C   MET C 176       0.020 -14.391  25.030  1.00 95.02           C
ATOM   3427  O   MET C 176       0.478 -14.899  26.041  1.00 97.70           O
ATOM   3428  N   ALA C 177      -0.388 -13.119  24.986  1.00 93.77           N
ATOM   3429  CA  ALA C 177      -0.331 -12.269  26.182  1.00 92.52           C
ATOM   3430  CB  ALA C 177      -0.664 -10.836  25.861  1.00 90.01           C
ATOM   3431  C   ALA C 177      -1.234 -12.770  27.285  1.00 92.95           C
ATOM   3432  O   ALA C 177      -0.820 -12.828  28.431  1.00 88.49           O
ATOM   3433  N   ARG C 178      -2.466 -13.138  26.912  1.00 97.25           N
ATOM   3434  CA  ARG C 178      -3.500 -13.544  27.858  1.00 96.54           C
ATOM   3435  CB  ARG C 178      -4.857 -13.726  27.195  1.00 95.44           C
ATOM   3436  CG  ARG C 178      -5.623 -12.448  27.099  1.00103.21           C
ATOM   3437  CD  ARG C 178      -7.128 -12.635  26.987  1.00110.30           C
ATOM   3438  NE  ARG C 178      -7.638 -11.754  25.935  1.00116.64           N
ATOM   3439  CZ  ARG C 178      -8.790 -11.929  25.300  1.00119.57           C
ATOM   3440  NH1 ARG C 178      -9.579 -12.944  25.638  1.00120.47           N
ATOM   3441  NH2 ARG C 178      -9.143 -11.096  24.322  1.00121.61           N
ATOM   3442  C   ARG C 178      -3.073 -14.824  28.488  1.00 98.48           C
ATOM   3443  O   ARG C 178      -3.312 -15.048  29.683  1.00101.98           O
ATOM   3444  N   GLN C 179      -2.419 -15.659  27.689  1.00 99.67           N
ATOM   3445  CA  GLN C 179      -1.948 -16.933  28.184  1.00102.47           C
ATOM   3446  CB  GLN C 179      -1.491 -17.812  27.045  1.00111.15           C
ATOM   3447  CG  GLN C 179      -1.320 -19.242  27.441  1.00122.02           C
ATOM   3448  CD  GLN C 179      -0.392 -19.964  26.490  1.00130.64           C
ATOM   3449  OE1 GLN C 179      -0.346 -19.674  25.258  1.00131.84           O
ATOM   3450  NE2 GLN C 179       0.372 -20.912  27.047  1.00132.53           N
ATOM   3451  C   GLN C 179      -0.817 -16.664  29.138  1.00 95.60           C
ATOM   3452  O   GLN C 179      -0.686 -17.307  30.173  1.00 86.64           O
ATOM   3453  N   ALA C 180      -0.040 -15.645  28.803  1.00 98.45           N
ATOM   3454  CA  ALA C 180       1.162 -15.342  29.564  1.00 99.91           C
ATOM   3455  CB  ALA C 180       2.005 -14.288  28.871  1.00 96.04           C
ATOM   3456  C   ALA C 180       0.737 -14.895  30.934  1.00 99.48           C
ATOM   3457  O   ALA C 180       1.325 -15.314  31.917  1.00101.60           O
ATOM   3458  N   GLU C 181      -0.328 -14.089  30.961  1.00101.49           N
ATOM   3459  CA  GLU C 181      -0.870 -13.421  32.152  1.00100.28           C
ATOM   3460  CB  GLU C 181      -1.962 -12.467  31.710  1.00 96.14           C
ATOM   3461  CG  GLU C 181      -2.657 -11.706  32.778  1.00 97.21           C
ATOM   3462  CD  GLU C 181      -3.935 -11.005  32.233  1.00101.20           C
ATOM   3463  OE1 GLU C 181      -4.545 -11.481  31.210  1.00 95.29           O
ATOM   3464  OE2 GLU C 181      -4.328  -9.962  32.843  1.00103.80           O
ATOM   3465  C   GLU C 181      -1.434 -14.460  33.089  1.00103.07           C
ATOM   3466  O   GLU C 181      -1.210 -14.406  34.313  1.00100.37           O
ATOM   3467  N   ALA C 182      -2.147 -15.418  32.484  1.00107.17           N
ATOM   3468  CA  ALA C 182      -2.779 -16.513  33.204  1.00105.89           C
ATOM   3469  CB  ALA C 182      -3.572 -17.375  32.272  1.00104.56           C
ATOM   3470  C   ALA C 182      -1.723 -17.318  33.923  1.00106.48           C
ATOM   3471  O   ALA C 182      -1.954 -17.707  35.057  1.00106.96           O
ATOM   3472  N   GLU C 183      -0.571 -17.542  33.284  1.00109.19           N
ATOM   3473  CA  GLU C 183       0.510 -18.330  33.904  1.00117.32           C
ATOM   3474  CB  GLU C 183       1.630 -18.721  32.915  1.00119.94           C
ATOM   3475  CG  GLU C 183       1.400 -20.076  32.167  1.00126.97           C
ATOM   3476  CD  GLU C 183       1.844 -20.081  30.640  1.00128.56           C
ATOM   3477  OE1 GLU C 183       2.128 -18.992  30.068  1.00136.53           O
ATOM   3478  OE2 GLU C 183       1.899 -21.170  29.997  1.00128.88           O
ATOM   3479  C   GLU C 183       1.085 -17.634  35.130  1.00114.41           C
ATOM   3480  O   GLU C 183       1.265 -18.275  36.155  1.00117.67           O
ATOM   3481  N   ARG C 184       1.357 -16.334  35.042  1.00111.15           N
ATOM   3482  CA  ARG C 184       1.902 -15.597  36.182  1.00108.08           C
ATOM   3483  CB  ARG C 184       2.197 -14.139  35.826  1.00107.87           C
ATOM   3484  CG  ARG C 184       3.044 -13.842  34.632  1.00106.93           C
ATOM   3485  CD  ARG C 184       2.941 -12.333  34.421  1.00112.52           C
ATOM   3486  NE  ARG C 184       4.041 -11.780  33.625  1.00117.88           N
ATOM   3487  CZ  ARG C 184       4.166 -10.495  33.268  1.00117.90           C
ATOM   3488  NH1 ARG C 184       3.262  -9.596  33.631  1.00119.28           N
ATOM   3489  NH2 ARG C 184       5.197 -10.107  32.526  1.00115.88           N
ATOM   3490  C   ARG C 184       0.892 -15.597  37.347  1.00107.08           C
ATOM   3491  O   ARG C 184       1.277 -15.545  38.531  1.00101.50           O
ATOM   3492  N   GLU C 185      -0.396 -15.618  36.976  1.00108.73           N
ATOM   3493  CA  GLU C 185      -1.556 -15.475  37.888  1.00110.63           C
ATOM   3494  CB  GLU C 185      -2.822 -15.103  37.040  1.00113.03           C
ATOM   3495  CG  GLU C 185      -4.007 -14.326  37.687  1.00115.99           C
ATOM   3496  CD  GLU C 185      -3.583 -13.181  38.616  1.00122.02           C
ATOM   3497  OE1 GLU C 185      -2.537 -12.537  38.339  1.00121.83           O
ATOM   3498  OE2 GLU C 185      -4.300 -12.919  39.629  1.00124.79           O
ATOM   3499  C   GLU C 185      -1.713 -16.770  38.727  1.00109.78           C
ATOM   3500  O   GLU C 185      -1.936 -16.706  39.937  1.00107.38           O
ATOM   3501  N   ARG C 186      -1.579 -17.921  38.046  1.00112.09           N
ATOM   3502  CA  ARG C 186      -1.401 -19.269  38.618  1.00109.24           C
ATOM   3503  CB  ARG C 186      -1.188 -20.285  37.459  1.00112.56           C
ATOM   3504  CG  ARG C 186      -0.857 -21.761  37.802  1.00116.44           C
ATOM   3505  CD  ARG C 186      -2.075 -22.652  37.566  1.00123.13           C
ATOM   3506  NE  ARG C 186      -2.067 -23.859  38.402  1.00126.82           N
ATOM   3507  CZ  ARG C 186      -3.135 -24.358  39.039  1.00127.71           C
ATOM   3508  NH1 ARG C 186      -4.328 -23.777  38.959  1.00128.16           N
ATOM   3509  NH2 ARG C 186      -3.004 -25.445  39.778  1.00127.88           N
ATOM   3510  C   ARG C 186      -0.229 -19.262  39.622  1.00106.31           C
ATOM   3511  O   ARG C 186      -0.442 -19.397  40.822  1.00103.12           O
ATOM   3512  N   ARG C 187       0.991 -19.074  39.108  1.00105.33           N
ATOM   3513  CA  ARG C 187       2.252 -19.036  39.877  1.00105.15           C
ATOM   3514  CB  ARG C 187       3.330 -18.411  39.019  1.00112.05           C
ATOM   3515  CG  ARG C 187       4.578 -19.251  38.901  1.00122.21           C
ATOM   3516  CD  ARG C 187       5.254 -18.905  37.597  1.00129.27           C
ATOM   3517  NE  ARG C 187       4.804 -19.868  36.580  1.00136.70           N
ATOM   3518  CZ  ARG C 187       5.353 -19.980  35.376  1.00140.86           C
ATOM   3519  NH1 ARG C 187       6.374 -19.168  35.031  1.00143.98           N
ATOM   3520  NH2 ARG C 187       4.873 -20.904  34.528  1.00140.75           N
ATOM   3521  C   ARG C 187       2.221 -18.243  41.161  1.00101.37           C
ATOM   3522  O   ARG C 187       2.685 -18.708  42.191  1.00 98.72           O
ATOM   3523  N   ALA C 188       1.711 -17.020  41.056  1.00102.56           N
ATOM   3524  CA  ALA C 188       1.488 -16.108  42.176  1.00101.20           C
ATOM   3525  CB  ALA C 188       1.017 -14.776  41.644  1.00 95.80           C
ATOM   3526  C   ALA C 188       0.523 -16.652  43.272  1.00101.74           C
ATOM   3527  O   ALA C 188       0.739 -16.434  44.482  1.00 97.57           O
ATOM   3528  N   ARG C 189      -0.525 -17.369  42.856  1.00105.78           N
ATOM   3529  CA  ARG C 189      -1.396 -18.064  43.809  1.00108.53           C
ATOM   3530  CB  ARG C 189      -2.564 -18.722  43.111  1.00111.48           C
ATOM   3531  CG  ARG C 189      -3.863 -17.997  43.278  1.00121.46           C
ATOM   3532  CD  ARG C 189      -4.670 -18.028  41.972  1.00129.77           C
ATOM   3533  NE  ARG C 189      -4.650 -19.349  41.319  1.00133.38           N
ATOM   3534  CZ  ARG C 189      -4.999 -19.588  40.050  1.00135.75           C
ATOM   3535  NH1 ARG C 189      -5.425 -18.598  39.253  1.00136.11           N
ATOM   3536  NH2 ARG C 189      -4.919 -20.831  39.575  1.00137.16           N
ATOM   3537  C   ARG C 189      -0.624 -19.109  44.603  1.00108.49           C
ATOM   3538  O   ARG C 189      -0.873 -19.290  45.792  1.00114.12           O
ATOM   3539  N   ILE C 190       0.322 -19.778  43.956  1.00103.13           N
ATOM   3540  CA  ILE C 190       1.061 -20.836  44.603  1.00 99.14           C
ATOM   3541  CB  ILE C 190       1.821 -21.712  43.593  1.00101.73           C
ATOM   3542  CG1 ILE C 190       0.832 -22.233  42.532  1.00100.40           C
ATOM   3543  CD1 ILE C 190       0.941 -23.721  42.241  1.00104.27           C
ATOM   3544  CG2 ILE C 190       2.655 -22.821  44.335  1.00101.31           C
ATOM   3545  C   ILE C 190       2.022 -20.265  45.590  1.00 94.30           C
ATOM   3546  O   ILE C 190       1.998 -20.604  46.757  1.00 94.59           O
ATOM   3547  N   THR C 191       2.878 -19.396  45.109  1.00 94.07           N
ATOM   3548  CA  THR C 191       3.898 -18.789  45.960  1.00 98.07           C
ATOM   3549  CB  THR C 191       4.612 -17.738  45.193  1.00 96.31           C
ATOM   3550  OG1 THR C 191       4.741 -18.245  43.876  1.00 96.17           O
ATOM   3551  CG2 THR C 191       5.979 -17.449  45.837  1.00 98.74           C
ATOM   3552  C   THR C 191       3.333 -18.118  47.195  1.00 97.64           C
ATOM   3553  O   THR C 191       3.932 -18.196  48.296  1.00 90.96           O
ATOM   3554  N   LEU C 192       2.204 -17.437  46.976  1.00 96.33           N
ATOM   3555  CA  LEU C 192       1.492 -16.814  48.050  1.00 95.75           C
ATOM   3556  CB  LEU C 192       0.197 -16.178  47.575  1.00 96.37           C
ATOM   3557  CG  LEU C 192      -0.344 -15.397  48.767  1.00 95.04           C
ATOM   3558  CD1 LEU C 192       0.705 -14.392  49.268  1.00 94.34           C
ATOM   3559  CD2 LEU C 192      -1.606 -14.711  48.429  1.00 95.58           C
ATOM   3560  C   LEU C 192       1.198 -17.831  49.133  1.00 95.36           C
ATOM   3561  O   LEU C 192       1.599 -17.617  50.285  1.00 97.31           O
ATOM   3562  N   ALA C 193       0.516 -18.922  48.767  1.00 92.22           N
ATOM   3563  CA  ALA C 193       0.218 -19.988  49.721  1.00 94.14           C
ATOM   3564  CB  ALA C 193      -0.702 -21.019  49.115  1.00 92.76           C
ATOM   3565  C   ALA C 193       1.503 -20.623  50.315  1.00 99.12           C
ATOM   3566  O   ALA C 193       1.644 -20.687  51.550  1.00 98.76           O
ATOM   3567  N   GLU C 194       2.460 -21.041  49.470  1.00101.70           N
ATOM   3568  CA  GLU C 194       3.739 -21.518  50.015  1.00103.58           C
ATOM   3569  CB  GLU C 194       4.740 -22.012  48.942  1.00102.50           C
ATOM   3570  CG  GLU C 194       5.861 -22.941  49.504  1.00104.97           C
ATOM   3571  CD  GLU C 194       5.275 -24.192  50.226  1.00110.80           C
ATOM   3572  OE1 GLU C 194       4.322 -24.786  49.689  1.00113.20           O
ATOM   3573  OE2 GLU C 194       5.714 -24.575  51.342  1.00110.61           O
ATOM   3574  C   GLU C 194       4.379 -20.517  51.007  1.00104.59           C
ATOM   3575  O   GLU C 194       4.977 -20.929  51.999  1.00106.68           O
ATOM   3576  N   ALA C 195       4.226 -19.216  50.763  1.00105.21           N
ATOM   3577  CA  ALA C 195       4.880 -18.219  51.608  1.00104.47           C
ATOM   3578  CB  ALA C 195       5.001 -16.906  50.907  1.00104.00           C
ATOM   3579  C   ALA C 195       4.129 -18.042  52.887  1.00105.48           C
ATOM   3580  O   ALA C 195       4.741 -17.810  53.928  1.00106.13           O
ATOM   3581  N   GLU C 196       2.805 -18.139  52.796  1.00107.75           N
ATOM   3582  CA  GLU C 196       1.933 -17.988  53.933  1.00112.30           C
ATOM   3583  CB  GLU C 196       0.471 -17.938  53.461  1.00123.74           C
ATOM   3584  CG  GLU C 196      -0.576 -17.476  54.515  1.00137.59           C
ATOM   3585  CD  GLU C 196      -1.769 -18.491  54.756  1.00143.59           C
ATOM   3586  OE1 GLU C 196      -1.762 -19.648  54.239  1.00146.00           O
ATOM   3587  OE2 GLU C 196      -2.719 -18.124  55.497  1.00144.26           O
ATOM   3588  C   GLU C 196       2.221 -19.173  54.851  1.00109.95           C
ATOM   3589  O   GLU C 196       2.679 -18.979  55.971  1.00106.53           O
ATOM   3590  N   ARG C 197       2.003 -20.386  54.330  1.00112.07           N
ATOM   3591  CA  ARG C 197       2.235 -21.692  55.001  1.00113.91           C
ATOM   3592  CB  ARG C 197       2.231 -22.793  53.928  1.00119.09           C
ATOM   3593  CG  ARG C 197       1.945 -24.233  54.373  1.00125.54           C
ATOM   3594  CD  ARG C 197       2.899 -25.221  53.687  1.00128.42           C
ATOM   3595  NE  ARG C 197       4.201 -25.201  54.373  1.00133.55           N
ATOM   3596  CZ  ARG C 197       5.246 -25.969  54.047  1.00134.78           C
ATOM   3597  NH1 ARG C 197       5.151 -26.819  53.019  1.00139.53           N
ATOM   3598  NH2 ARG C 197       6.389 -25.888  54.734  1.00134.07           N
ATOM   3599  C   ARG C 197       3.556 -21.771  55.781  1.00111.35           C
ATOM   3600  O   ARG C 197       3.618 -22.306  56.899  1.00113.11           O
ATOM   3601  N   GLN C 198       4.614 -21.254  55.175  1.00105.22           N
ATOM   3602  CA  GLN C 198       5.919 -21.290  55.785  1.00103.15           C
ATOM   3603  CB  GLN C 198       6.994 -21.121  54.735  1.00108.32           C
ATOM   3604  CG  GLN C 198       7.218 -22.342  53.882  1.00113.13           C
ATOM   3605  CD  GLN C 198       8.308 -22.102  52.868  1.00116.08           C
ATOM   3606  OE1 GLN C 198       9.366 -21.511  53.197  1.00117.99           O
ATOM   3607  NE2 GLN C 198       8.062 -22.534  51.615  1.00114.28           N
ATOM   3608  C   GLN C 198       6.109 -20.227  56.824  1.00100.23           C
ATOM   3609  O   GLN C 198       6.871 -20.407  57.761  1.00100.96           O
ATOM   3610  N   ALA C 199       5.459 -19.087  56.637  1.00101.25           N
ATOM   3611  CA  ALA C 199       5.510 -18.018  57.640  1.00 99.07           C
ATOM   3612  CB  ALA C 199       4.835 -16.739  57.120  1.00 97.98           C
ATOM   3613  C   ALA C 199       4.812 -18.548  58.901  1.00 95.44           C
ATOM   3614  O   ALA C 199       5.306 -18.326  60.029  1.00 84.68           O
ATOM   3615  N   ALA C 200       3.688 -19.267  58.666  1.00 94.30           N
ATOM   3616  CA  ALA C 200       2.917 -20.011  59.688  1.00 92.27           C
ATOM   3617  CB  ALA C 200       1.784 -20.847  59.036  1.00 81.77           C
ATOM   3618  C   ALA C 200       3.831 -20.902  60.542  1.00 97.08           C
ATOM   3619  O   ALA C 200       3.831 -20.799  61.796  1.00 92.97           O
ATOM   3620  N   GLU C 201       4.619 -21.747  59.851  1.00101.82           N
ATOM   3621  CA  GLU C 201       5.486 -22.702  60.514  1.00105.43           C
ATOM   3622  CB  GLU C 201       5.979 -23.765  59.559  1.00117.07           C
ATOM   3623  CG  GLU C 201       5.216 -25.104  59.677  1.00131.97           C
ATOM   3624  CD  GLU C 201       5.525 -26.029  58.477  1.00140.81           C
ATOM   3625  OE1 GLU C 201       6.740 -26.332  58.247  1.00143.90           O
ATOM   3626  OE2 GLU C 201       4.564 -26.419  57.750  1.00141.46           O
ATOM   3627  C   GLU C 201       6.632 -22.049  61.238  1.00100.40           C
ATOM   3628  O   GLU C 201       6.913 -22.382  62.391  1.00 97.93           O
ATOM   3629  N   LYS C 202       7.289 -21.105  60.588  1.00 98.84           N
ATOM   3630  CA  LYS C 202       8.291 -20.355  61.293  1.00 99.43           C
ATOM   3631  CB  LYS C 202       9.061 -19.460  60.355  1.00102.10           C
ATOM   3632  CG  LYS C 202      10.287 -20.161  59.895  1.00112.42           C
ATOM   3633  CD  LYS C 202      10.384 -19.991  58.407  1.00125.38           C
ATOM   3634  CE  LYS C 202      11.689 -20.573  57.792  1.00130.69           C
ATOM   3635  NZ  LYS C 202      12.231 -19.719  56.622  1.00133.26           N
ATOM   3636  C   LYS C 202       7.714 -19.626  62.519  1.00 99.81           C
ATOM   3637  O   LYS C 202       8.412 -19.404  63.515  1.00 98.94           O
ATOM   3638  N   LEU C 203       6.428 -19.298  62.479  1.00 99.26           N
ATOM   3639  CA  LEU C 203       5.796 -18.650  63.633  1.00 97.55           C
ATOM   3640  CB  LEU C 203       4.576 -17.838  63.201  1.00 91.22           C
ATOM   3641  CG  LEU C 203       4.735 -16.391  62.751  1.00 83.85           C
ATOM   3642  CD1 LEU C 203       3.281 -15.923  62.450  1.00 80.17           C
ATOM   3643  CD2 LEU C 203       5.528 -15.513  63.757  1.00 70.93           C
ATOM   3644  C   LEU C 203       5.394 -19.655  64.711  1.00 99.95           C
ATOM   3645  O   LEU C 203       5.537 -19.385  65.917  1.00101.30           O
ATOM   3646  N   ARG C 204       4.857 -20.786  64.252  1.00100.94           N
ATOM   3647  CA  ARG C 204       4.628 -21.954  65.072  1.00101.61           C
ATOM   3648  CB  ARG C 204       4.011 -23.043  64.180  1.00106.96           C
ATOM   3649  CG  ARG C 204       3.886 -24.396  64.791  1.00118.42           C
ATOM   3650  CD  ARG C 204       4.028 -25.529  63.738  1.00127.49           C
ATOM   3651  NE  ARG C 204       4.421 -26.757  64.451  1.00135.74           N
ATOM   3652  CZ  ARG C 204       3.570 -27.664  64.975  1.00140.08           C
ATOM   3653  NH1 ARG C 204       2.236 -27.549  64.852  1.00137.39           N
ATOM   3654  NH2 ARG C 204       4.063 -28.721  65.628  1.00143.82           N
ATOM   3655  C   ARG C 204       5.948 -22.360  65.822  1.00100.01           C
ATOM   3656  O   ARG C 204       5.961 -22.445  67.070  1.00 94.81           O
ATOM   3657  N   GLU C 205       7.063 -22.550  65.100  1.00 99.17           N
ATOM   3658  CA  GLU C 205       8.313 -22.869  65.806  1.00103.47           C
ATOM   3659  CB  GLU C 205       9.302 -23.768  64.999  1.00109.51           C
ATOM   3660  CG  GLU C 205      10.235 -23.179  63.910  1.00113.23           C
ATOM   3661  CD  GLU C 205      10.074 -23.914  62.538  1.00118.57           C
ATOM   3662  OE1 GLU C 205       9.056 -24.638  62.350  1.00123.32           O
ATOM   3663  OE2 GLU C 205      10.928 -23.758  61.628  1.00116.47           O
ATOM   3664  C   GLU C 205       8.944 -21.691  66.565  1.00103.09           C
ATOM   3665  O   GLU C 205       9.784 -21.877  67.444  1.00104.26           O
ATOM   3666  N   ALA C 206       8.497 -20.484  66.232  1.00101.93           N
ATOM   3667  CA  ALA C 206       8.767 -19.294  67.019  1.00 97.56           C
ATOM   3668  CB  ALA C 206       8.129 -18.106  66.391  1.00100.14           C
ATOM   3669  C   ALA C 206       8.135 -19.505  68.337  1.00 97.37           C
ATOM   3670  O   ALA C 206       8.746 -19.215  69.353  1.00 89.76           O
ATOM   3671  N   ALA C 207       6.893 -20.014  68.284  1.00104.23           N
ATOM   3672  CA  ALA C 207       6.019 -20.231  69.456  1.00105.87           C
ATOM   3673  CB  ALA C 207       4.588 -20.551  69.062  1.00 99.41           C
ATOM   3674  C   ALA C 207       6.540 -21.239  70.473  1.00108.68           C
ATOM   3675  O   ALA C 207       6.525 -20.887  71.653  1.00108.91           O
ATOM   3676  N   GLU C 208       6.996 -22.446  70.058  1.00111.10           N
ATOM   3677  CA  GLU C 208       7.604 -23.416  71.030  1.00113.54           C
ATOM   3678  CB  GLU C 208       8.309 -24.628  70.416  1.00118.77           C
ATOM   3679  CG  GLU C 208       7.970 -24.971  69.013  1.00131.59           C
ATOM   3680  CD  GLU C 208       6.867 -25.983  68.946  1.00137.79           C
ATOM   3681  OE1 GLU C 208       6.571 -26.554  70.028  1.00139.28           O
ATOM   3682  OE2 GLU C 208       6.311 -26.203  67.825  1.00141.95           O
ATOM   3683  C   GLU C 208       8.687 -22.715  71.819  1.00110.39           C
ATOM   3684  O   GLU C 208       8.660 -22.663  73.055  1.00111.22           O
ATOM   3685  N   ILE C 209       9.661 -22.188  71.097  1.00105.53           N
ATOM   3686  CA  ILE C 209      10.792 -21.590  71.764  1.00106.43           C
ATOM   3687  CB  ILE C 209      11.791 -20.898  70.779  1.00105.06           C
ATOM   3688  CG1 ILE C 209      12.275 -21.878  69.675  1.00103.86           C
ATOM   3689  CD1 ILE C 209      13.222 -21.265  68.593  1.00101.95           C
ATOM   3690  CG2 ILE C 209      12.939 -20.265  71.550  1.00100.40           C
ATOM   3691  C   ILE C 209      10.351 -20.670  72.917  1.00110.52           C
ATOM   3692  O   ILE C 209      10.946 -20.731  73.983  1.00113.08           O
ATOM   3693  N   ILE C 210       9.304 -19.862  72.731  1.00116.01           N
ATOM   3694  CA  ILE C 210       8.884 -18.942  73.808  1.00122.77           C
ATOM   3695  CB  ILE C 210       8.210 -17.602  73.310  1.00122.69           C
ATOM   3696  CG1 ILE C 210       8.707 -17.174  71.923  1.00121.49           C
ATOM   3697  CD1 ILE C 210       7.812 -16.137  71.238  1.00121.76           C
ATOM   3698  CG2 ILE C 210       8.445 -16.458  74.342  1.00122.50           C
ATOM   3699  C   ILE C 210       8.032 -19.624  74.897  1.00129.07           C
ATOM   3700  O   ILE C 210       8.086 -19.231  76.058  1.00128.25           O
ATOM   3701  N   SER C 211       7.264 -20.646  74.515  1.00139.17           N
ATOM   3702  CA  SER C 211       6.535 -21.505  75.461  1.00147.89           C
ATOM   3703  CB  SER C 211       5.733 -22.574  74.719  1.00148.78           C
ATOM   3704  OG  SER C 211       4.346 -22.383  74.907  1.00152.69           O
ATOM   3705  C   SER C 211       7.478 -22.228  76.395  1.00154.29           C
ATOM   3706  O   SER C 211       7.746 -21.769  77.513  1.00156.46           O
ATOM   3707  N   GLU C 212       7.971 -23.362  75.899  1.00160.15           N
ATOM   3708  CA  GLU C 212       8.846 -24.287  76.616  1.00166.23           C
ATOM   3709  CB  GLU C 212       9.208 -25.420  75.646  1.00166.96           C
ATOM   3710  CG  GLU C 212      10.098 -26.536  76.155  1.00168.78           C
ATOM   3711  CD  GLU C 212      10.942 -27.116  75.027  1.00169.61           C
ATOM   3712  OE1 GLU C 212      10.390 -27.322  73.914  1.00168.15           O
ATOM   3713  OE2 GLU C 212      12.155 -27.344  75.251  1.00168.99           O
ATOM   3714  C   GLU C 212      10.103 -23.642  77.278  1.00169.87           C
ATOM   3715  O   GLU C 212      10.742 -24.274  78.131  1.00171.89           O
ATOM   3716  N   HIS C 213      10.422 -22.388  76.931  1.00171.67           N
ATOM   3717  CA  HIS C 213      11.624 -21.709  77.453  1.00173.62           C
ATOM   3718  CB  HIS C 213      12.816 -22.039  76.524  1.00175.43           C
ATOM   3719  CG  HIS C 213      14.158 -21.616  77.053  1.00178.36           C
ATOM   3720  ND1 HIS C 213      15.343 -22.084  76.520  1.00178.60           N
ATOM   3721  CE1 HIS C 213      16.360 -21.545  77.172  1.00178.36           C
ATOM   3722  NE2 HIS C 213      15.881 -20.748  78.112  1.00178.21           N
ATOM   3723  CD2 HIS C 213      14.507 -20.776  78.062  1.00178.95           C
ATOM   3724  C   HIS C 213      11.483 -20.166  77.630  1.00173.52           C
ATOM   3725  O   HIS C 213      11.994 -19.414  76.802  1.00173.82           O
ATOM   3726  N   PRO C 214      10.814 -19.679  78.708  1.00173.70           N
ATOM   3727  CA  PRO C 214      10.805 -18.206  78.835  1.00172.10           C
ATOM   3728  CB  PRO C 214       9.503 -17.912  79.612  1.00173.02           C
ATOM   3729  CG  PRO C 214       9.089 -19.244  80.262  1.00174.00           C
ATOM   3730  CD  PRO C 214      10.063 -20.328  79.804  1.00174.81           C
ATOM   3731  C   PRO C 214      12.044 -17.652  79.562  1.00170.11           C
ATOM   3732  O   PRO C 214      12.004 -17.328  80.750  1.00168.40           O
ATOM   3733  OXT PRO C 214      13.124 -17.513  78.975  1.00167.77           O
END
【図面の簡単な説明】
【００４４】
【図１】全ての三つの生物ドメイン（古細菌、バクテリア、真核生物）で高度に保存されているストマチンのオルソログ。一次配列アライメントはClustalW (http://align.genome.jp/)で作成された。また、PhStoCD の二次構造(chain A) も併置された。二次構造のうちa helixはバネ構造で、βstrandは黒矢印で示された。黒点は10残基ごとの目盛りとして付された。赤い背景の白文字は完全に保存されているアミノ酸残基を、赤文字は類似のアミノ酸残基を表す。黒楔印は1510-N プロテアーゼで水解されるPH1511p の238 番目残基と239番目残基の間の切断点を示す。
【図２】ストマチンPH1511pのハイドロパシープロット（Ａ）と欠失変異体のコード領域（Ｂ）を表す。（Ａ）黒線は予測された膜貫通領域を示す。（Ｂ）赤字は高発現され精製標品が得られた三つの欠失変異体、1511-C1 (168-266)、1511-N2 (56-165)、1511-N3 (56-234)を表す。なお、この表記法ではカッコ内に領域の最初と最後の残基番号が付されている。
【図３】PhStoCD の結晶を示す写真。
【図４】リボンモデルで表示されたPhStoCDの三次元構造（A、B、Cサブユニットは各々青色、緑色、暖色で示された）。図4Aは三つのα/βドメインが形成する三角形構造体を上面から俯瞰したステレオ図。図4Bは側面からのステレオ図。図4Cは結晶パッキングと結晶学的対称分子を示す。
【図５】空間充填モデルで表されたPhStoCDの三次元構造。図5AとBはPhStoCD 3量体を空間充填モデルで現し、その表面を塩基性アミノ酸側鎖を青色、酸性アミノ酸側鎖を赤色、疎水性アミノ酸側鎖を白色で表示した。図5Aは三角形構造体を斜め上から見たステレオ図を表し、図5Bは三角形構造体下面から見たステレオ図を示す。図5CはPhStoCDを空間充填モデルで現し、三角形構造体を斜め上から見たステレオ図に、極性アミノ酸残基を緑色で、疎水性アミノ酸側鎖を白色で区別した。
【図２】
2009143857.tif 000002
【図１】
2009143857.tif 000003
【図３】
2009143857.tif 000004
【図４】
2009143857.tif 000005
【図５】
2009143857.tif 000006
【配列表】
2009143857000001.app