(57)【要約】【課題】  β−グリコシダーゼの基質の検索およびβ−グリコシダーゼを任意の変異操作によって改良するための手段を提供する。【課題解決手段】  高品位のβ−グリコシダーゼの結晶を得て、Ｘ線結晶構造解析し、その三次元構造を解明し、該３次元構造データを用いて、上記基質の検索及び該酵素変位体の機能等を予測する。【特許請求の範囲】
【請求項１】
β−グリコシダーゼの結晶。
【請求項２】
結晶の空間群がＣ２であり格子定数がa=１２２．５６Å、ｂ＝６１．１７Å、ｃ＝  ７３．７４Å、α＝９０°、β＝９２．４７°、γ＝９０°である請求項１記載のβ−グリコシダーゼの結晶。
【請求項３】
β−グリコシダーゼがパイロコッカス・ホリコシ（Ｐｙｒｏｃｏｃｃｕｓ  ｈｏｒｉｋｏｓｈｉｉ）ＯＴ３に由来するものである請求項１又は２に記載のβ−グリコシダーゼの結晶。
【請求項４】
その結晶の大きさが０．０２×０．３×１．５ｍｍまでのものであることを特徴とする請求項１記載のβ−グリコシダーゼの結晶。
【請求項５】
界面活性剤を含む精製β−グリコシダーゼ溶液に、沈殿剤としてリン酸アンモニウムを用い、ハンギングドロップ法により結晶化することを特徴とする請求項１〜４のいずれかに記載のβ−グリコシダーゼの結晶の製造方法。
【請求項６】
リン酸アンモニウムの濃度が０．９〜１．１Ｍである沈殿剤溶液を用いる請求項５記載の製造方法。
【請求項７】
β−グリコシダーゼがパイロコッカス・ホリコシＯＴ３に由来するβ−グリコシダーゼであり、かつβ−グリコシダーゼのタンパク質濃度が４〜５ｍｇ／ｍｌであることを特徴とする請求項５記載の製造方法。
【請求項８】
界面活性剤がトライトンＸ−１００（Ｔｒｉｔｏｎ Ｘ−１００）であり、その濃度が０．９〜１．１ＣＭＣであるタンパク質溶液を用いることを特徴とする請求項５記載の製造方法。
【請求項９】
請求項１〜４のいずれかに記載のβ−グリコシダーゼの結晶を用いて、Ｘ線結晶構造解析を行うことによって得られるβ−グリコシダーゼの三次元構造。
【請求項１０】
請求項９に記載のβ−グリコシダーゼの三次元構造の原子座標データを格納した記録媒体。
【発明の詳細な説明】
【技術分野】
【０００１】
本発明は、β−グリコシダーゼの結晶、より詳細には、パイロコッカス属に属する超好熱性細菌由来の耐熱性β−グリコシダーゼの結晶、その製造方法、並びにその三次元構造及び該３次元構造の原子座標データを格納した記録媒体に関する。
【背景技術】
【０００２】
β−グリコシダーゼは糖質の加水分解、シークエンシング、糖タンパク質、糖脂質の構造解析、光学純度の高いオリゴ糖、複合糖質の合成に有用な酵素である。その反応は基質を構成する単糖の種類、グリコシド結合の光学異性、結合位置に特異的である。β−グリコシダーゼは糖鎖の修飾や立体光学異性を保持したオリゴ糖や多糖の合成に有用であるとともに、グリコシド基を１級アルコール、２級アルコール、３級アルコールに転移するので、バイオサーファクタント等の複合糖質の合成に有用である。
【０００３】
パイロコッカス由来の耐熱性β−グリコシダーゼは、至適温度が１００℃以上であり、界面活性剤の存在下で高い活性を有すると共に、アルキルグルコシド等の複合糖質の加水分解に優れている（特許文献１参照）。既知の基質化合物以外にも配糖体、糖脂質等の中には基質となる化合物が多く存在すると考えられる。加水分解の逆反応、転移反応が可能となれば生分解性界面活性剤として有用なアルキルグルコシド等を合成できる。
β−グリコシダーゼが基質とする化合物の探索、あるいはβ−グリコシダーゼを改変して合成反応を高めるためにはβ−グリコシダーゼの活性部位および基質結合部位のアミノ酸組成とその三次元配列が必要であり、したがって、β−グリコシダーゼの立体構造の解明が渇望されていた。
【特許文献１】特開２０００−５０８７０号公報
【発明の開示】
【発明が解決しようとする課題】
【０００４】
本発明の目的は、β−グリコシダーゼの結晶、その結晶の製造方法を提供するとともに、該結晶を用いてＸ線結晶構造解析により得られるβ−グリコシダーゼの三次元構造を明らかにすることである。
【課題を解決するための手段】
【０００５】
本発明者らは、上記特許文献（特開２０００−５０８７０号公報）記載のパイロコッカス由来の耐熱性β−グリコシダーゼを素材として用い、該酵素の三次元構造を解明し得る高品位の該酵素の結晶を得るべく鋭意検討を重ねた結果、約１ＣＭＣの界面活性剤トライトンＸ−１００を含む該酵素の水溶液に対して約１Ｍのリン酸２水素１アンモニウムを沈殿剤として用いることにより該酵素の結晶を得ることに成功した。そして、その結晶にＸ線を当てることにより、分解能約１．５ÅのＸ線回折強度が得られることを確認した。
【０００６】
更に、本発明者らは、前記β−グリコシダーゼの結晶についてＸ線結晶構造解析を行うことにより、その三次元構造を明らかにすることが可能であることを実証し、それらの知見に基づき本発明を完成するに至った。
【０００７】
すなわち、本発明は、β−グリコシダーゼの結晶に関する。特に該結晶は、パイロコッカス由来の耐熱性のβ−グリコシダーゼの結晶であって、Ｘ線結晶構造解析によりその三次元構造を側鎖のレベルまで解明し得る品位を有する。
【０００８】
上記結晶においては、結晶の空間群がＣ２であり、格子定数がａ=１２２．５６Å、ｂ＝６１．１７Å、ｃ＝  ７３．７４Å、α＝９０°、β＝９２．４７°、γ＝９０°である。また、その結晶の大きさは、０．０２×０．３×１．５ｍｍまでのものである。
【０００９】
さらに、本発明は、界面活性剤トライトンＸ−１００を含む精製β−グリコシダーゼ溶液に沈殿剤としてリン酸２水素１アンモニウムを用い、ハンギングドロップ法により結晶化することを特徴とする、上記β−グリコシダーゼの結晶の製造方法に関する。
【００１０】
さらに、本発明は、上記β−グリコシダーゼの結晶を用いて、Ｘ線結晶構造解析を行うことにより得られるβ−グリコシダーゼの三次元構造に関するものであり、また、該３次元構造の原子座標データを格納した記録媒体に関する。
【発明の効果】
【００１１】
本発明のβ−グリコシダーゼの結晶は、Ｘ線回折実験を行うことによって分解能約２．５ÅのＸ線回折強度を得られるだけの品位を有しており、β−グリコシダーゼの三次元構造を側鎖のレベルまで解明できる。また、このようにして解明されたβ−グリコシダーゼの三次元構造を用いれば、その基質結合部位のアミノ酸残基とその立体配置が明らかとなり、該酵素に適した基質の探索のための候補を絞り込むことができるとともに、該酵素の活性中心のアミノ酸残基の配置が明らかとなり、それによって改良型の酵素を得るために変異させるべき残基をかなり絞り込むことができる。すなわち、部位特異的変異によって特定の残基を任意のアミノ酸に置換し、得られた変異体について機能の検討を行って、加水分解の逆反応や転移反応などの優れた変異体を得ることが可能となる。
【発明を実施するための最良の形態】
【００１２】
以下、本発明を詳細に説明する。本発明のβ−グリコシダーゼ結晶を得るための素材としては、上記特許文献（特開２０００−５０８７０号公報）記載のパイロコッカス由来の耐熱性β−グリコシダーゼが好ましく用いられる。
【００１３】
該耐熱性β−グリコシダーゼは、上記特許文献（特開２０００−５０８７０号公報）および松井らの報告（Ｍａｔｓｕｉ，Ｉ．，Ｓａｋａｉ，Ｙ．，Ｍａｔｓｕｉ，Ｅ．，Ｋｉｋｕｃｈｉ，Ｈ．，Ｋａｗａｒａｂａｙａｓｈｉ，Ｙ．，ａｎｄ  Ｈｏｎｄａ，Ｋ．（２０００)  ＦＥＢＳ  Ｌｅｔｔ．，４６７，１９５−２００）に記載されているがごとく、４２３アミノ酸残基より構成され、その分子量は４５，０００Ｄａである。該酵素はβ−１，３−グリコシド結合およびβ−１，４−グリコシド結合に高い活性を示し、２糖類と種々の配糖体を良く分解する。とりわけ、還元末端に芳香族や長鎖アルキル基を含むβ−グリコシドを良い基質とする。
【００１４】
該酵素の至適ｐＨは６．０、至適温度は１００℃以上である。該酵素は２０％のエタノール或いはメタノール存在下ｐＨ６．０、６０℃で溶媒非存在下の各々７７％、６８％の活性を保持しており、従って、極めて高い熱安定性と有機溶媒耐性を有している。
【００１５】
上記の様な性質を有する、パイロコッカス由来の耐熱性β−グリコシダーゼの、上記特許文献（特開２０００−５０８７０号公報）記載の方法により精製された標品は、以下に示す結晶化における素材として用いられる。次いで、β−グリコシダーゼの結晶化について述べる。
【００１６】
一般にタンパク質の結晶化は容易ではなく、多くのタンパク質の場合は、数多くの条件検討を重ねて初めてＸ線結晶構造解析に供することのできる結晶が得られる。また、いかなる条件でも結晶化しないタンパク質も決して少なくなく、タンパク質の結晶が得られなければＸ線結晶構造解析を行うことができず、従って、そのタンパク質の三次元構造を解明することはできない。
【００１７】
現在、タンパク質の三次元構造を決めるための方法として、ＮＭＲ（核磁気共鳴法）を利用することも可能である。ＮＭＲでは試料を結晶化する必要はなく、タンパク質溶液の状態で測定を行うことができる。しかし、ＮＭＲで構造を決めるのが可能なタンパク質は事実上分子量が１万以下に限定される。従って、分子量の大きなβ−グリコシダーゼについては、Ｘ線結晶構造解析に頼らざるを得ないのが現状である。
【００１８】
また、Ｘ線結晶解析の際、タンパク質の結晶がいかなるものであっても解析可能であるわけではない。そのＸ線解析装置の能力によって違いはあるが、測定に供しうるタンパク質の結晶の条件としては、単結晶であって、その大きさが大きいものが好ましく、０．１ｍｍ角以上であることが求められる。いずれにしても、Ｘ線を当てた際に解析可能な分解能の回折強度データが得られることが必要である。特に、タンパク質のアミノ酸残基の向きまで含めた構造解析を行うのであれば、最低でも３Å程度の分解能が必要とされる。
【００１９】
本発明のβ−グリコシダーゼを結晶化するには、まず前記した結晶化の素材となるβ−グリコシダーゼは、薄い緩衝液中に濃縮された状態で用意するのが好ましく、その際の緩衝液のｐＨは該酵素の安定ｐＨの範囲内であることが望ましい。該酵素を濃縮することによって該酵素の沈殿が生ずる場合は界面活性剤を添加するなどにより沈殿の生成を抑えることが望ましい。従って、必要に応じて、例えば、１０〜１００ｍＭのリン酸緩衝液（ｐＨ６．０）に１ＣＭＣ濃度となるようにトライトンＸ−１００を添加した溶液を用いて、β−グリコシダーゼの濃度を４〜５ｍｇ／ｍｌ程度まで濃縮する。次いで、β−グリコシダーゼの濃縮液に種々の沈殿剤を加えることにより結晶化のための好適な沈殿剤を検索する。
【００２０】
本発明のβ−グリコシダーゼの結晶化の検索に利用される沈殿剤としては様々なものを用いることができ、例えば、硫酸アンモニウムなどの無機塩類、ポリエチレングリコール類、エタノールなどの有機溶媒類などが挙げられる。ハンプトン・リサーチ社製の「ＭｅｍｂＦａｃ」を用いて種々の沈殿剤を検討した結果、０．１Ｍ硫酸リチウム、０．１Ｍ酢酸ナトリウム、１Ｍのリン酸２水素１アンモニウムを含むｐＨ４．６の溶液を沈殿剤として用いることにより、本発明の目的とする結晶が得られることを見いだした。また、結晶化の温度は常温であればいかなる温度でもよいが、好ましくは約２０℃で１週間以上静置すればよい。
【００２１】
上記条件における結晶化の実施態様としては、ハンギングドロップ法、透析法、シッティングドロップ法などの公知のいかなる方法でもよいが、好ましくは蒸気拡散法の一種であるハンギングドロップ法が好適に用いられる。
【００２２】
このハンギングドロップ法は、密閉系においてタンパク質を含む低濃度の沈殿剤溶液から高濃度の沈殿剤溶液に水が拡散してゆく原理を利用したものであり、最も一般的に用いられる結晶化方法である。
【００２３】
上記のようにして得られる結晶の外観、および結晶の最小単位である単位格子の種類・サイズ、格子内の分子の数・対称性などはその結晶に固有のものであり、同一のタンパク質でかつ沈殿剤の種類が同じであっても異なる結晶が得られることがある。ただし、同一のタンパク質であれば、結晶の外観が異なっていても分子の三次元構造は同一であると考えられる。
【００２４】
このような方法により、Ｘ線結晶構造解析に供してその酵素の三次元構造を側鎖レベルまで解明しうる品位を有する本発明のβ−グリコシダーゼの結晶を得ることができる。
【００２５】
このようにして得られた結晶にＸ線を当てて回折強度データを得るには、通常の実験室レベルのＸ線回折装置としては、ＳＭＡＲＴ６０００(ブルカーＡＸＳ社)などが用いられるが、好ましくは放射光由来の強いＸ線を利用できる放射光施設、例えば、つくばの高エネルギー加速器研究機構の放射光施設にてＸ線回折強度データの収集を行うことが望ましい。
【００２６】
このようにして得られたＸ線回折強度データのパターンより結晶学的パラメーターを決定することができ、例えば、当該結晶の場合は、単斜晶系に属しており、空間群がＣ２、格子定数はa=１２２．５６Å、ｂ＝６１．１７Å、ｃ＝  ７３．７４Å、α＝９０°、β＝９２．４７°、γ＝９０°である。そして、計算により導き出される該結晶の溶媒含有率は５２．１％であり、非対称単位内にβ−グリコシダーゼを１分子含むものと推定された。また、前記データの分解能は２．５Åであり、側鎖の向きも含めた三次元構造の決定が可能なレベルにあった。
【００２７】
次いで、上記のようにして得られたＸ線回折強度データに基づいてその結晶を構成する分子の電子密度図を導き出すためには、分子置換法や重原子同型置換法による位相の決定が必要となるが、該分子とホモロジーの高い別のタンパク質分子の構造が公知の場合は、分子置換法を用いることができる。
【００２８】
当該β−グリコシダーゼの構造を分子置換法で決めるためには、そのアミノ酸配列において高い相同性を有し、かつ立体構造が公知であるβ−グリコシダーゼの構造、好ましくは、当該β−グリコシダーゼと３２．１％の相同性を有しており、その立体構造がよく似ていると推定されるスルホロブス・ソルファタリカス（Ｓｕｌｕｆｏｒｏｂｕｓ ｓｏｌｆａｔａｒｉｃｕｓ）由来のβ−グリコシダーゼの構造が用いられる。すなわち、プロテインデータバンク（Ｐｒｏｔｅｉｎ Ｄａｔａ Ｂａｎｋ）に登録されている（登録番号１ＧＯＷ）スルホロブス・ソルファタリカス由来のβ−グリコシダーゼの原子座標を用いることにより当該β−グリコシダーゼの結晶構造の初期モデルを導き出すことができる。なお、初期モデルを導き出す過程においては、種々のプログラムを用いることが可能であるが、例えば、Ｘ−ＰＬＯＲ（Ｂｒｕｎｇｅｒ，Ａ．Ｔ．，, Ｋｕｒｉｙａｎ， Ｊ． ＆ Ｋａｒｐｌｕｓ、Ｍ． (１９８７) Ｓｃｉｅｎｃｅ, ３５, ４５８−４６０）などのソフトウエアが利用できる。
【００２９】
次に、分子置換法により良好な初期構造モデルが得られれば、その電子密度を描くことができ、それに基づいて、モデルの修正を、三次元グラフィックス上にて行うことができる。その際に、種々のプログラムを用いることが可能であるが、好ましくは、Ｔｕｒｂｏ−Ｆｒｏｄｏ（ＡＦＭＢ−ＣＮＲＳ, フランス）を用いて、アミノ酸残基の違いの修正、電子密度からのずれの修正を行う。
【００３０】
さらに、構築された分子のモデルは種々のプログラムを用いて精密化する必要があるが、例えばＸ−ＰＬＯＲなどのプログラムによる精密化と、プログラムＴｕｒｂｏ−Ｆｒｏｄｏを用いた三次元グラフィックスによる修正作業を駆使して、より正解に近い構造へと近づけていくことができる。精密化の指標となるＲ因子の値が２０％以下になることが目標とされている。例えば、当該β−グリコシダーゼの場合は、Ｒ因子が１７．６％まで下がった時点で精密化を終えた。表１は当該グリコシダーゼの三次元構造の精密化後の原子座標である。該原子座標データは、磁気、光デイスク等のそれ自体周知の記録媒体に格納できる。該記録媒体に格納されたデータはＴｕｒｂｏ−Ｆｒｏｄｏ、ＩｎｓｉｇｈｔＩＩ（Ａｃｃｅｌｒｙｓ社）等の画像作製プログラム等に入力し画像化して、新たな基質の探索等に利用できるとともに  当該グリコシダーゼのアミノ酸配列を変更した場合の３次元構造を画像化でき、グリコシターゼの基質特異性その他の機能・性質等を予想して酵素の改良等に利用できる。また、アミノ酸配列を改変したタンパク質の立体構造をＸ線結晶構造解析で決定する場合に、当該原子座標データを用いることによって、分子置換法により電子密度図を作成するための初期位相を計算することができる。
【００３１】
以下、実施例により本発明を更に詳細に説明するが、本発明の技術的範囲は、かかる実施例に限定されるものではない。
【実施例１】
【００３２】
β−グリコシダーゼの結晶化
結晶化の素材として、特開２０００−５０８７０号公報および松井らの報告（Ｍａｔｓｕｉ，Ｉ．，Ｓａｋａｉ，Ｙ．，Ｍａｔｓｕｉ，Ｅ．，Ｋｉｋｕｃｈｉ，Ｈ．，Ｋａｗａｒａｂａｙａｓｈｉ，Ｙ．，ａｎｄ  Ｈｏｎｄａ，Ｋ．（２０００)  ＦＥＢＳ  Ｌｅｔｔ．，４６７，１９５−２００）に記載されているパイロコッカス・ホリコシ（登録番号JCM9974)由来の耐熱性β−グリコシダーゼを用いた。その遺伝子の塩基配列及びアミノ酸配列を配列番号１に示す。なお、該遺伝子を有する発現プラスミドにより形質転換された形質転換体(E.coli BL21(DE3)pET15b/Gly2M)は工業技術院生命工学技術研究所にＦＥＲＭ−  Ｐ１６８９として登録されている。 
【００３３】
このβ−グリコシダーゼを４．２ｍｇを、０．９ｍＭのトライトンＸ−１００を含み、５０ｍＭのリン酸緩衝液でｐＨを６．０に調製した溶液１ｍｌに溶解させたものをタンパク質溶液として用いた。
【００３４】
一方、沈殿剤溶液としては、０．１Ｍの硫酸リチウムと１Ｍのリン酸２水素１アンモニウムを含み、酢酸緩衝液でｐＨを４．６に調製した溶液を用いた。
【００３５】
結晶化は公知のハンギングドロップ法により、以下のとおりに行った。すなわち、上記の沈殿剤溶液を組織培養用のマルチウエル・プレート（直径１８ｍｍ、２４穴）の各穴に１ｍｌずつ入れ、リザーバー溶液とした。次にシリコンコートした直径１８ｍｍのカバーグラスの中央にβ−グリコシダーゼ溶液を２μｌのせ、すぐに同量の前記リザーバー溶液を加え、手早く攪拌した。そのカバーグラスを静かに反転させ、リザーバーの入った穴を塞ぐように蓋をした。その際、接着部分にはあらかじめシリコングリースをぬっておいて密閉を確かなものとした。リザーバー溶液中には、タンパク質を含むドロップの溶液中の２倍の濃度のリン酸アンモニウムが含まれる計算になるので、タンパク質溶液中の水は徐々に蒸発してリザーバー溶液中に拡散してゆく。また、タンパク質溶液中のリン酸アンモニウムの濃度は徐々にリザーバー溶液のそれに近づいてゆき、解けきれなくなったタンパク質が徐々に結晶化した。２０℃で一週間以上静置することにより結晶が成長し、本発明の目的にかなった結晶が得られ、図１に示すような大きいもので、約０．０１×０．１×１．０ｍｍに達するβ−グリコシダーゼの結晶を得た。
【実施例２】
【００３６】
Ｘ線回折強度データの収集
実施例１で得られたβ−グリコシダーゼの結晶の中から、大きく厚い単結晶を選択し、Ｘ線回折実験に供した。測定に供した結晶は、幅０．０５〜０．１ｍｍ、長さ０．５〜１ｍｍ、厚さ０．００５〜０．０１ｍｍ程度のものであった。前記のβ−グリコシダーゼの結晶にＸ線を当てて回折強度データを測定するために、Ｘ線回折装置としてＢｒｕｋｅｒ社製のＳＭＡＲＴ６０００を用いた。結晶は、厚さ１０μｍ、内径０．５ｍｍのガラス管に封入して測定に供した。Ｘ線は銅のＫα線を用い、結晶カメラ間距離を６ｃｍ、１２０秒／０．２°で測定を行った。更に、高分解能のＸ線回折データを精度良く測定するために高エネルギー加速器研究機構の放射光施設のＢＬ６Ａビームラインを用いて測定を行った。
【００３７】
実施例２で得られた、図２に示すようなＸ線回折強度データのパターンより、特定した結晶学的パラメーターを以下に示す。本発明によるβ−グリコシダーゼの結晶の属する晶系は単斜晶系であり、空間群はＣ２であり、格子定数はａ=１２２．５６Å、ｂ＝６１．１７Å、ｃ＝  ７３．７４Å、α＝９０°、β＝９２．４７°、γ＝９０°であった。また、計算によって導き出した溶媒の含有率は５２．１％であり、非対称単位にβ−グリコシダーゼを１分子含むものと推定された。なお、放射光施設のＢＬ６Ａビームラインを用いて測定したデータの分解能は約２．５Åであり、側鎖の向きも含めた三次元構造の決定が可能なレベルにあった。
【実施例３】
【００３８】
構造モデルの作製と精密化
実施例２で得られたＸ線回折強度データに基づいて該結晶を構成するβ−グリコシダーゼ分子の立体構造を導き出すために、公知であるスルホロブス・ソルファタリカス（Ｓｕｌｆｏｌｏｂｕｓ ｓｏｌｆａｔａｒｉｃｕｓ）由来のβ−グリコシダーゼの原子座標（Ｐｒｏｔｅｉｎ Ｄａｔａ Ｂａｎｋ、登録番号１ＧＯＷ）を用いて分子置換法により初期構造モデルを計算した。すなわち、スルホロブス・ソルファタリカス由来のβ−グリコシダーゼと当該β−グリコシダーゼはアミノ酸配列の相同性が３２．１％であり、従って、立体構造は良く似ていると推定されるため、その分子を当該β−グリコシダーゼ分子と見なして、結晶内での向きと位置をプログラムＸ−ＰＬＯＲを用いて決定した。次いで、β−グリコシダーゼ分子の電子密度図を計算し、アミノ酸配列を修正し、電子密度と構造モデルのずれの修正を行うことによって、当該β−グリコシダーゼの立体構造モデルを構築した。このようにして構築したβ−グリコシダーゼの初期モデルを、プログラムＸ−ＰＬＯＲを用いて精密化した。そして、Ｘ−ＰＬＯＲによる精密化とプログラムＴｕｒｂｏ−Ｆｒｏｄｏを用いた修正作業を駆使して、構造の修正を繰り返した。精密化の指標となるＲ因子の値は１７．６％まで下がった。また、表１にβ−グリコシダーゼの結晶構造の原子座標を示す。
【００３９】
このような過程を経て得られたβ−グリコシダーゼの三次元構造のモデルを図３に示す。この三次元構造から、活性部位のアミノ酸配列とそれらの側鎖の詳細な構造を知ることができる。従って、本発明によれば、その三次元構造に基づいた活性部位のアミノ酸残基の配列から該酵素に適した基質の探索のための候補を絞り込むことができる。さらに、該酵素の活性中心のアミノ酸残基の配置が明らかとなり、それによって改良型の酵素を得るために変異させるべき残基を絞り込むことができる。すなわち、部位特異的変異によって特定の残基を任意のアミノ酸に置換し、得られた変異体について機能の検討を行って、加水分解の逆反応や転移反応などの活性を向上させた優れた変異体を得ることができる。
【産業上の利用可能性】
【００４０】
当該β−グリコシダーゼは至適温度が１００℃以上であり、極めて熱安定性の高い酵素であり、工業的利用が期待されている。その三次元構造を明らかにすることによって、産業上有用な基質の探索が容易となる。更に、活性中心近傍のアミノ酸残基をターゲットとした部位特的変異の導入による酵素の改変によって、界面活性剤となる糖脂質の合成を行う転移反応や加水分解の逆反応などの機能を向上させた酵素への改変が可能となるので、本発明は産業上極めて有用である。
（表１）β−グリコシダーゼ結晶の原子座標
ATOM      1  N   MET     1     -14.746  41.852  51.307  1.00 65.25
ATOM      2  CA  MET     1     -13.581  42.496  50.724  1.00 65.17
ATOM      3  C   MET     1     -12.514  41.477  50.317  1.00 63.75
ATOM      4  O   MET     1     -12.634  40.318  50.723  1.00 64.02
ATOM      5  CB  MET     1     -13.074  43.481  51.756  1.00 67.04
ATOM      6  CG  MET     1     -13.813  44.801  51.610  1.00 68.98
ATOM      7  SD  MET     1     -13.059  45.730  50.245  1.00 71.57
ATOM      8  CE  MET     1     -14.124  45.506  48.833  1.00 71.41
ATOM      9  N   PRO     2     -11.499  41.758  49.481  1.00 61.96
ATOM     10  CA  PRO     2     -10.344  40.874  49.282  1.00 59.94
ATOM     11  C   PRO     2      -9.399  40.923  50.477  1.00 57.54
ATOM     12  O   PRO     2      -9.400  41.884  51.253  1.00 57.33
ATOM     13  CB  PRO     2      -9.678  41.362  48.009  1.00 60.39
ATOM     14  CG  PRO     2     -10.658  42.358  47.426  1.00 61.14
ATOM     15  CD  PRO     2     -11.389  42.939  48.635  1.00 61.43
ATOM     16  N   LEU     3      -8.564  39.911  50.669  1.00 55.10
ATOM     17  CA  LEU     3      -7.606  39.963  51.751  1.00 52.95
ATOM     18  C   LEU     3      -6.522  40.824  51.162  1.00 51.68
ATOM     19  O   LEU     3      -5.842  40.414  50.225  1.00 51.08
ATOM     20  CB  LEU     3      -7.028  38.600  52.087  1.00 52.89
ATOM     21  CG  LEU     3      -6.813  38.302  53.559  1.00 52.39
ATOM     22  CD1 LEU     3      -8.155  38.071  54.176  1.00 52.48
ATOM     23  CD2 LEU     3      -6.014  37.042  53.768  1.00 52.56
ATOM     24  N   LYS     4      -6.442  42.052  51.637  1.00 50.13
ATOM     25  CA  LYS     4      -5.443  42.955  51.135  1.00 49.54
ATOM     26  C   LYS     4      -4.220  43.008  52.053  1.00 49.05
ATOM     27  O   LYS     4      -4.361  42.956  53.285  1.00 48.62
ATOM     28  CB  LYS     4      -6.126  44.299  50.969  1.00 50.16
ATOM     29  CG  LYS     4      -7.402  44.223  50.089  1.00 51.16
ATOM     30  CD  LYS     4      -7.905  45.614  49.704  1.00 51.56
ATOM     31  CE  LYS     4      -7.462  45.941  48.281  1.00 52.15
ATOM     32  NZ  LYS     4      -6.037  45.733  48.015  1.00 52.59
ATOM     33  N   PHE     5      -3.013  43.045  51.481  1.00 48.21
ATOM     34  CA  PHE     5      -1.746  43.059  52.201  1.00 47.82
ATOM     35  C   PHE     5      -1.101  44.409  52.046  1.00 47.71
ATOM     36  O   PHE     5      -1.296  45.040  51.016  1.00 48.92
ATOM     37  CB  PHE     5      -0.788  42.018  51.664  1.00 46.91
ATOM     38  CG  PHE     5      -1.136  40.705  52.321  1.00 47.48
ATOM     39  CD1 PHE     5      -0.511  40.348  53.514  1.00 47.43
ATOM     40  CD2 PHE     5      -2.069  39.851  51.737  1.00 48.09
ATOM     41  CE1 PHE     5      -0.797  39.137  54.136  1.00 47.46
ATOM     42  CE2 PHE     5      -2.351  38.635  52.367  1.00 48.59
ATOM     43  CZ  PHE     5      -1.714  38.274  53.563  1.00 48.20
ATOM     44  N   PRO     6      -0.378  44.950  53.015  1.00 47.13
ATOM     45  CA  PRO     6       0.140  46.299  52.943  1.00 47.11
ATOM     46  C   PRO     6       1.050  46.555  51.753  1.00 47.83
ATOM     47  O   PRO     6       1.788  45.678  51.342  1.00 48.20
ATOM     48  CB  PRO     6       0.800  46.452  54.272  1.00 46.76
ATOM     49  CG  PRO     6      -0.054  45.603  55.171  1.00 46.11
ATOM     50  CD  PRO     6      -0.190  44.367  54.327  1.00 46.37
ATOM     51  N   GLU     7       1.033  47.782  51.237  1.00 49.26
ATOM     52  CA  GLU     7       1.843  48.267  50.114  1.00 49.89
ATOM     53  C   GLU     7       3.254  47.752  50.064  1.00 48.87
ATOM     54  O   GLU     7       3.659  47.112  49.112  1.00 48.97
ATOM     55  CB  GLU     7       1.922  49.802  50.131  1.00 52.44
ATOM     56  CG  GLU     7       1.609  50.555  51.479  1.00 55.51
ATOM     57  CD  GLU     7       2.656  50.751  52.606  1.00 57.05
ATOM     58  OE1 GLU     7       3.118  49.763  53.214  1.00 57.39
ATOM     59  OE2 GLU     7       2.962  51.924  52.905  1.00 57.38
ATOM     60  N   MET     8       3.988  47.972  51.143  1.00 47.90
ATOM     61  CA  MET     8       5.382  47.579  51.222  1.00 46.82
ATOM     62  C   MET     8       5.504  46.109  51.634  1.00 43.83
ATOM     63  O   MET     8       6.580  45.781  52.129  1.00 44.28
ATOM     64  CB  MET     8       6.110  48.446  52.256  1.00 49.61
ATOM     65  CG  MET     8       6.074  49.959  52.058  1.00 53.01
ATOM     66  SD  MET     8       6.943  50.629  50.608  1.00 56.89
ATOM     67  CE  MET     8       7.615  51.985  51.544  1.00 56.87
ATOM     68  N   PHE     9       4.518  45.187  51.503  1.00 39.16
ATOM     69  CA  PHE     9       4.726  43.840  51.999  1.00 35.01
ATOM     70  C   PHE     9       5.499  43.134  50.916  1.00 34.80
ATOM     71  O   PHE     9       5.356  43.408  49.707  1.00 36.23
ATOM     72  CB  PHE     9       3.417  43.099  52.245  1.00 31.45
ATOM     73  CG  PHE     9       3.456  41.884  53.198  1.00 28.16
ATOM     74  CD1 PHE     9       3.616  40.594  52.707  1.00 26.75
ATOM     75  CD2 PHE     9       3.234  42.051  54.565  1.00 26.34
ATOM     76  CE1 PHE     9       3.538  39.505  53.564  1.00 25.45
ATOM     77  CE2 PHE     9       3.157  40.957  55.402  1.00 24.65
ATOM     78  CZ  PHE     9       3.306  39.683  54.911  1.00 24.16
ATOM     79  N   LEU    10       6.398  42.266  51.373  1.00 33.11
ATOM     80  CA  LEU    10       7.200  41.535  50.435  1.00 31.35
ATOM     81  C   LEU    10       6.581  40.183  50.293  1.00 30.82
ATOM     82  O   LEU    10       6.233  39.537  51.288  1.00 31.70
ATOM     83  CB  LEU    10       8.618  41.402  50.937  1.00 30.77
ATOM     84  CG  LEU    10       9.394  42.689  51.132  1.00 30.25
ATOM     85  CD1 LEU    10      10.793  42.352  51.651  1.00 30.17
ATOM     86  CD2 LEU    10       9.440  43.460  49.822  1.00 29.09
ATOM     87  N   PHE    11       6.442  39.796  49.041  1.00 29.64
ATOM     88  CA  PHE    11       5.929  38.515  48.638  1.00 28.88
ATOM     89  C   PHE    11       7.062  37.972  47.793  1.00 29.33
ATOM     90  O   PHE    11       7.255  38.382  46.640  1.00 30.16
ATOM     91  CB  PHE    11       4.707  38.698  47.807  1.00 28.09
ATOM     92  CG  PHE    11       3.412  38.940  48.571  1.00 27.83
ATOM     93  CD1 PHE    11       2.765  37.883  49.196  1.00 27.12
ATOM     94  CD2 PHE    11       2.838  40.220  48.593  1.00 28.28
ATOM     95  CE1 PHE    11       1.546  38.096  49.836  1.00 26.99
ATOM     96  CE2 PHE    11       1.621  40.422  49.236  1.00 27.66
ATOM     97  CZ  PHE    11       0.978  39.354  49.854  1.00 27.21
ATOM     98  N   GLY    12       7.869  37.065  48.341  1.00 30.16
ATOM     99  CA  GLY    12       9.077  36.624  47.661  1.00 28.68
ATOM    100  C   GLY    12       9.270  35.138  47.774  1.00 27.87
ATOM    101  O   GLY    12       8.472  34.451  48.393  1.00 27.72
ATOM    102  N   THR    13      10.292  34.589  47.149  1.00 27.60
ATOM    103  CA  THR    13      10.568  33.190  47.308  1.00 27.50
ATOM    104  C   THR    13      11.969  33.086  47.929  1.00 28.07
ATOM    105  O   THR    13      12.644  34.104  48.091  1.00 28.47
ATOM    106  CB  THR    13      10.424  32.553  45.913  1.00 27.77
ATOM    107  OG1 THR    13      11.466  33.029  45.055  1.00 27.39
ATOM    108  CG2 THR    13       9.040  32.870  45.339  1.00 26.83
ATOM    109  N   ALA    14      12.453  31.902  48.313  1.00 29.25
ATOM    110  CA  ALA    14      13.693  31.699  49.069  1.00 29.48
ATOM    111  C   ALA    14      14.458  30.460  48.613  1.00 30.06
ATOM    112  O   ALA    14      13.904  29.435  48.157  1.00 29.88
ATOM    113  CB  ALA    14      13.391  31.514  50.558  1.00 28.41
ATOM    114  N   THR    15      15.769  30.581  48.717  1.00 30.37
ATOM    115  CA  THR    15      16.674  29.505  48.370  1.00 31.06
ATOM    116  C   THR    15      17.919  29.622  49.278  1.00 31.77
ATOM    117  O   THR    15      18.085  30.538  50.133  1.00 31.59
ATOM    118  CB  THR    15      17.098  29.578  46.827  1.00 30.75
ATOM    119  OG1 THR    15      17.466  30.912  46.473  1.00 29.62
ATOM    120  CG2 THR    15      15.975  29.116  45.917  1.00 30.71
ATOM    121  N   SER    16      18.793  28.621  49.120  1.00 32.18
ATOM    122  CA  SER    16      20.105  28.794  49.675  1.00 32.53
ATOM    123  C   SER    16      21.057  29.003  48.478  1.00 33.68
ATOM    124  O   SER    16      20.872  29.998  47.689  1.00 34.76
ATOM    125  CB  SER    16      20.439  27.584  50.559  1.00 31.57
ATOM    126  OG  SER    16      20.595  26.348  49.895  1.00 32.26
ATOM    127  N   SER    17      22.077  28.135  48.401  1.00 32.73
ATOM    128  CA  SER    17      23.150  28.247  47.449  1.00 32.48
ATOM    129  C   SER    17      23.637  26.850  47.254  1.00 32.02
ATOM    130  O   SER    17      23.735  26.441  46.098  1.00 31.96
ATOM    131  CB  SER    17      24.308  29.088  47.963  1.00 33.12
ATOM    132  OG  SER    17      24.700  28.816  49.313  1.00 34.32
ATOM    133  N   HIS    18      23.857  26.075  48.330  1.00 31.16
ATOM    134  CA  HIS    18      24.320  24.698  48.108  1.00 31.37
ATOM    135  C   HIS    18      23.253  23.859  47.360  1.00 31.69
ATOM    136  O   HIS    18      23.583  23.016  46.504  1.00 30.97
ATOM    137  CB  HIS    18      24.694  23.984  49.458  1.00 28.55
ATOM    138  CG  HIS    18      25.398  22.652  49.212  1.00 26.93
ATOM    139  CD2 HIS    18      25.116  21.464  49.858  1.00 26.86
ATOM    140  ND1 HIS    18      26.349  22.400  48.319  1.00 25.57
ATOM    141  CE1 HIS    18      26.640  21.119  48.408  1.00 25.64
ATOM    142  NE2 HIS    18      25.895  20.558  49.331  1.00 25.78
ATOM    143  N   GLN    19      21.985  24.192  47.686  1.00 32.41
ATOM    144  CA  GLN    19      20.820  23.506  47.170  1.00 32.92
ATOM    145  C   GLN    19      20.486  23.818  45.699  1.00 33.86
ATOM    146  O   GLN    19      19.920  22.931  45.045  1.00 33.87
ATOM    147  CB  GLN    19      19.634  23.863  48.037  1.00 32.18
ATOM    148  CG  GLN    19      19.737  23.367  49.431  1.00 32.21
ATOM    149  CD  GLN    19      18.600  23.772  50.373  1.00 32.81
ATOM    150  OE1 GLN    19      18.605  24.820  51.034  1.00 33.23
ATOM    151  NE2 GLN    19      17.600  22.940  50.563  1.00 32.57
ATOM    152  N   ILE    20      20.796  25.023  45.149  1.00 34.42
ATOM    153  CA  ILE    20      20.437  25.415  43.775  1.00 34.26
ATOM    154  C   ILE    20      21.639  25.636  42.855  1.00 36.03
ATOM    155  O   ILE    20      21.574  25.412  41.637  1.00 35.89
ATOM    156  CB  ILE    20      19.586  26.739  43.698  1.00 33.32
ATOM    157  CG2 ILE    20      18.399  26.625  44.635  1.00 32.60
ATOM    158  CG1 ILE    20      20.395  27.959  44.071  1.00 32.53
ATOM    159  CD1 ILE    20      19.636  29.265  43.916  1.00 32.81
ATOM    160  N   GLU    21      22.758  26.161  43.349  1.00 38.06
ATOM    161  CA  GLU    21      23.914  26.341  42.509  1.00 40.38
ATOM    162  C   GLU    21      24.549  24.997  42.734  1.00 42.49
ATOM    163  O   GLU    21      24.647  24.449  43.864  1.00 43.51
ATOM    164  CB  GLU    21      24.976  27.269  42.978  1.00 40.60
ATOM    165  CG  GLU    21      24.538  28.629  43.403  1.00 41.33
ATOM    166  CD  GLU    21      25.401  29.226  44.504  1.00 40.99
ATOM    167  OE1 GLU    21      26.238  28.525  45.071  1.00 40.35
ATOM    168  OE2 GLU    21      25.205  30.403  44.801  1.00 41.31
ATOM    169  N   GLY    22      24.956  24.509  41.566  1.00 42.67
ATOM    170  CA  GLY    22      25.628  23.241  41.586  1.00 42.40
ATOM    171  C   GLY    22      27.121  23.394  41.647  1.00 41.91
ATOM    172  O   GLY    22      27.659  24.501  41.540  1.00 41.16
ATOM    173  N   ASN    23      27.739  22.226  41.812  1.00 42.30
ATOM    174  CA  ASN    23      29.174  22.128  41.861  1.00 42.92
ATOM    175  C   ASN    23      29.844  23.105  42.825  1.00 43.56
ATOM    176  O   ASN    23      30.836  23.824  42.583  1.00 44.05
ATOM    177  CB  ASN    23      29.694  22.314  40.473  1.00 42.61
ATOM    178  CG  ASN    23      29.373  21.147  39.587  1.00 42.77
ATOM    179  OD1 ASN    23      29.013  20.037  39.985  1.00 43.13
ATOM    180  ND2 ASN    23      29.514  21.436  38.306  1.00 42.94
ATOM    181  N   ASN    24      29.262  23.126  44.011  1.00 43.60
ATOM    182  CA  ASN    24      29.850  23.898  45.068  1.00 44.06
ATOM    183  C   ASN    24      30.948  22.990  45.599  1.00 44.88
ATOM    184  O   ASN    24      30.734  22.267  46.577  1.00 45.41
ATOM    185  CB  ASN    24      28.831  24.169  46.129  1.00 43.57
ATOM    186  CG  ASN    24      28.358  25.586  46.103  1.00 43.49
ATOM    187  OD1 ASN    24      27.167  25.793  46.266  1.00 43.90
ATOM    188  ND2 ASN    24      29.187  26.613  45.954  1.00 43.72
ATOM    189  N   ARG    25      32.121  22.978  44.956  1.00 45.53
ATOM    190  CA  ARG    25      33.202  22.085  45.366  1.00 45.88
ATOM    191  C   ARG    25      33.869  22.318  46.715  1.00 45.43
ATOM    192  O   ARG    25      34.310  21.397  47.401  1.00 45.09
ATOM    193  CB  ARG    25      34.237  22.130  44.301  1.00 46.60
ATOM    194  CG  ARG    25      33.828  21.238  43.167  1.00 47.89
ATOM    195  CD  ARG    25      34.020  22.048  41.899  1.00 49.44
ATOM    196  NE  ARG    25      34.095  21.277  40.663  1.00 50.55
ATOM    197  CZ  ARG    25      33.185  20.376  40.268  1.00 51.58
ATOM    198  NH1 ARG    25      32.105  20.086  40.989  1.00 51.89
ATOM    199  NH2 ARG    25      33.318  19.786  39.079  1.00 52.08
ATOM    200  N   TRP    26      33.892  23.577  47.138  1.00 44.93
ATOM    201  CA  TRP    26      34.671  23.930  48.304  1.00 44.45
ATOM    202  C   TRP    26      34.044  23.867  49.688  1.00 42.68
ATOM    203  O   TRP    26      34.701  24.293  50.658  1.00 42.39
ATOM    204  CB  TRP    26      35.252  25.311  48.002  1.00 46.80
ATOM    205  CG  TRP    26      35.905  25.280  46.629  1.00 49.31
ATOM    206  CD2 TRP    26      35.517  26.022  45.552  1.00 51.06
ATOM    207  CE2 TRP    26      36.321  25.472  44.534  1.00 51.40
ATOM    208  CE3 TRP    26      34.624  27.057  45.277  1.00 52.20
ATOM    209  CD1 TRP    26      36.890  24.371  46.314  1.00 50.18
ATOM    210  NE1 TRP    26      37.114  24.503  45.031  1.00 50.40
ATOM    211  CZ2 TRP    26      36.231  25.963  43.227  1.00 52.24
ATOM    212  CZ3 TRP    26      34.538  27.550  43.968  1.00 52.45
ATOM    213  CH2 TRP    26      35.332  27.003  42.953  1.00 52.73
ATOM    214  N   ASN    27      32.832  23.294  49.834  1.00 39.75
ATOM    215  CA  ASN    27      32.208  23.221  51.157  1.00 37.81
ATOM    216  C   ASN    27      32.207  21.822  51.806  1.00 36.68
ATOM    217  O   ASN    27      32.488  20.777  51.199  1.00 36.07
ATOM    218  CB  ASN    27      30.720  23.777  51.137  1.00 37.02
ATOM    219  CG  ASN    27      29.678  23.080  50.253  1.00 36.85
ATOM    220  OD1 ASN    27      29.289  21.910  50.400  1.00 36.62
ATOM    221  ND2 ASN    27      29.128  23.773  49.274  1.00 35.89
ATOM    222  N   ASP    28      31.903  21.769  53.101  1.00 35.45
ATOM    223  CA  ASP    28      31.902  20.506  53.790  1.00 34.68
ATOM    224  C   ASP    28      30.812  19.532  53.361  1.00 34.53
ATOM    225  O   ASP    28      31.052  18.313  53.338  1.00 34.77
ATOM    226  CB  ASP    28      31.848  20.795  55.305  1.00 34.97
ATOM    227  CG  ASP    28      30.662  21.504  55.943  1.00 34.65
ATOM    228  OD1 ASP    28      30.186  22.480  55.375  1.00 34.49
ATOM    229  OD2 ASP    28      30.245  21.064  57.023  1.00 33.92
ATOM    230  N   TRP    29      29.603  19.990  53.009  1.00 33.62
ATOM    231  CA  TRP    29      28.585  19.082  52.482  1.00 32.80
ATOM    232  C   TRP    29      29.095  18.388  51.202  1.00 33.76
ATOM    233  O   TRP    29      29.014  17.158  51.094  1.00 31.84
ATOM    234  CB  TRP    29      27.303  19.862  52.178  1.00 31.32
ATOM    235  CG  TRP    29      26.336  19.874  53.349  1.00 30.58
ATOM    236  CD2 TRP    29      25.257  19.041  53.526  1.00 30.38
ATOM    237  CE2 TRP    29      24.762  19.475  54.763  1.00 30.01
ATOM    238  CE3 TRP    29      24.634  17.990  52.846  1.00 29.94
ATOM    239  CD1 TRP    29      26.483  20.743  54.391  1.00 30.30
ATOM    240  NE1 TRP    29      25.518  20.478  55.233  1.00 30.44
ATOM    241  CZ2 TRP    29      23.646  18.874  55.334  1.00 29.79
ATOM    242  CZ3 TRP    29      23.524  17.379  53.423  1.00 29.74
ATOM    243  CH2 TRP    29      23.034  17.817  54.652  1.00 29.94
ATOM    244  N   TRP    30      29.703  19.134  50.253  1.00 35.61
ATOM    245  CA  TRP    30      30.212  18.577  49.005  1.00 37.99
ATOM    246  C   TRP    30      31.136  17.423  49.293  1.00 38.67
ATOM    247  O   TRP    30      31.057  16.336  48.725  1.00 40.11
ATOM    248  CB  TRP    30      30.994  19.598  48.211  1.00 39.88
ATOM    249  CG  TRP    30      31.541  19.027  46.903  1.00 42.63
ATOM    250  CD2 TRP    30      30.949  19.100  45.669  1.00 44.12
ATOM    251  CE2 TRP    30      31.875  18.432  44.858  1.00 44.59
ATOM    252  CE3 TRP    30      29.787  19.625  45.107  1.00 45.27
ATOM    253  CD1 TRP    30      32.743  18.360  46.844  1.00 43.58
ATOM    254  NE1 TRP    30      32.909  18.013  45.592  1.00 44.64
ATOM    255  CZ2 TRP    30      31.660  18.284  43.489  1.00 45.40
ATOM    256  CZ3 TRP    30      29.568  19.477  43.735  1.00 45.14
ATOM    257  CH2 TRP    30      30.490  18.815  42.936  1.00 45.34
ATOM    258  N   TYR    31      32.057  17.668  50.190  1.00 39.46
ATOM    259  CA  TYR    31      33.013  16.667  50.603  1.00 38.96
ATOM    260  C   TYR    31      32.329  15.377  51.032  1.00 38.60
ATOM    261  O   TYR    31      32.653  14.291  50.530  1.00 38.45
ATOM    262  CB  TYR    31      33.863  17.291  51.744  1.00 39.08
ATOM    263  CG  TYR    31      34.800  16.310  52.383  1.00 38.80
ATOM    264  CD1 TYR    31      34.487  15.779  53.619  1.00 39.09
ATOM    265  CE1 TYR    31      35.293  14.813  54.180  1.00 40.02
ATOM    266  CD2 TYR    31      35.918  15.890  51.684  1.00 39.46
ATOM    267  CE2 TYR    31      36.736  14.923  52.238  1.00 40.12
ATOM    268  CZ  TYR    31      36.418  14.389  53.476  1.00 40.72
ATOM    269  OH  TYR    31      37.271  13.448  54.030  1.00 42.68
ATOM    270  N   TYR    32      31.355  15.465  51.928  1.00 38.48
ATOM    271  CA  TYR    32      30.788  14.241  52.446  1.00 38.83
ATOM    272  C   TYR    32      29.844  13.475  51.524  1.00 38.63
ATOM    273  O   TYR    32      29.539  12.301  51.782  1.00 37.84
ATOM    274  CB  TYR    32      30.125  14.596  53.693  1.00 40.18
ATOM    275  CG  TYR    32      31.069  14.884  54.840  1.00 41.78
ATOM    276  CD1 TYR    32      31.548  16.166  55.108  1.00 42.34
ATOM    277  CE1 TYR    32      32.288  16.403  56.272  1.00 43.71
ATOM    278  CD2 TYR    32      31.344  13.841  55.719  1.00 43.10
ATOM    279  CE2 TYR    32      32.077  14.052  56.884  1.00 43.87
ATOM    280  CZ  TYR    32      32.541  15.334  57.159  1.00 44.44
ATOM    281  OH  TYR    32      33.204  15.532  58.361  1.00 44.81
ATOM    282  N   GLU    33      29.379  14.213  50.492  1.00 38.46
ATOM    283  CA  GLU    33      28.558  13.796  49.350  1.00 37.25
ATOM    284  C   GLU    33      29.467  12.914  48.546  1.00 38.94
ATOM    285  O   GLU    33      29.252  11.710  48.453  1.00 38.53
ATOM    286  CB  GLU    33      28.109  15.036  48.519  1.00 34.36
ATOM    287  CG  GLU    33      26.772  15.509  49.059  1.00 31.37
ATOM    288  CD  GLU    33      26.362  16.942  48.827  1.00 30.75
ATOM    289  OE1 GLU    33      26.802  17.539  47.856  1.00 30.63
ATOM    290  OE2 GLU    33      25.606  17.484  49.633  1.00 29.59
ATOM    291  N   GLN    34      30.556  13.519  48.074  1.00 41.54
ATOM    292  CA  GLN    34      31.574  12.781  47.364  1.00 44.22
ATOM    293  C   GLN    34      32.185  11.616  48.148  1.00 44.79
ATOM    294  O   GLN    34      32.380  10.595  47.500  1.00 45.49
ATOM    295  CB  GLN    34      32.700  13.731  46.911  1.00 45.39
ATOM    296  CG  GLN    34      32.245  14.801  45.890  1.00 47.92
ATOM    297  CD  GLN    34      31.436  14.394  44.628  1.00 49.00
ATOM    298  OE1 GLN    34      30.621  15.169  44.134  1.00 49.97
ATOM    299  NE2 GLN    34      31.513  13.243  43.972  1.00 49.72
ATOM    300  N   ILE    35      32.516  11.600  49.447  1.00 45.01
ATOM    301  CA  ILE    35      33.062  10.362  49.987  1.00 45.71
ATOM    302  C   ILE    35      32.006   9.333  50.372  1.00 46.20
ATOM    303  O   ILE    35      32.330   8.193  50.712  1.00 45.54
ATOM    304  CB  ILE    35      33.991  10.630  51.216  1.00 46.19
ATOM    305  CG2 ILE    35      35.206  11.394  50.706  1.00 46.07
ATOM    306  CG1 ILE    35      33.304  11.387  52.324  1.00 46.62
ATOM    307  CD1 ILE    35      34.158  11.293  53.606  1.00 46.93
ATOM    308  N   GLY    36      30.737   9.751  50.367  1.00 47.68
ATOM    309  CA  GLY    36      29.578   8.886  50.592  1.00 48.37
ATOM    310  C   GLY    36      29.125   8.700  52.022  1.00 49.10
ATOM    311  O   GLY    36      28.770   7.577  52.390  1.00 49.04
ATOM    312  N   LYS    37      29.033   9.762  52.828  1.00 50.33
ATOM    313  CA  LYS    37      28.783   9.543  54.235  1.00 51.48
ATOM    314  C   LYS    37      27.342   9.697  54.636  1.00 51.89
ATOM    315  O   LYS    37      26.635   8.706  54.747  1.00 51.72
ATOM    316  CB  LYS    37      29.697  10.488  55.032  1.00 52.45
ATOM    317  CG  LYS    37      30.162   9.911  56.386  1.00 53.08
ATOM    318  CD  LYS    37      29.244  10.370  57.503  1.00 53.55
ATOM    319  CE  LYS    37      29.155   9.398  58.661  1.00 54.04
ATOM    320  NZ  LYS    37      28.567   8.137  58.233  1.00 54.63
ATOM    321  N   LEU    38      26.894  10.908  54.937  1.00 53.07
ATOM    322  CA  LEU    38      25.510  11.158  55.315  1.00 54.58
ATOM    323  C   LEU    38      25.231  12.658  55.086  1.00 54.72
ATOM    324  O   LEU    38      24.601  13.340  55.903  1.00 55.11
ATOM    325  CB  LEU    38      25.232  10.847  56.789  1.00 55.12
ATOM    326  CG  LEU    38      25.322   9.511  57.485  1.00 56.20
ATOM    327  CD1 LEU    38      25.036   9.740  58.972  1.00 56.37
ATOM    328  CD2 LEU    38      24.348   8.506  56.849  1.00 57.09
ATOM    329  N   PRO    39      25.627  13.290  53.983  1.00 53.91
ATOM    330  CA  PRO    39      25.287  12.925  52.616  1.00 54.11
ATOM    331  C   PRO    39      25.119  11.551  51.945  1.00 54.65
ATOM    332  O   PRO    39      26.128  10.891  51.699  1.00 54.83
ATOM    333  CB  PRO    39      26.254  13.777  51.916  1.00 53.41
ATOM    334  CG  PRO    39      26.072  15.069  52.622  1.00 53.02
ATOM    335  CD  PRO    39      26.199  14.621  54.030  1.00 53.15
ATOM    336  N   TYR    40      23.885  11.119  51.597  1.00 55.06
ATOM    337  CA  TYR    40      23.672   9.889  50.830  1.00 54.94
ATOM    338  C   TYR    40      23.021  10.143  49.445  1.00 53.63
ATOM    339  O   TYR    40      22.419   9.289  48.791  1.00 51.95
ATOM    340  CB  TYR    40      22.830   8.956  51.681  1.00 57.46
ATOM    341  CG  TYR    40      21.472   9.446  52.148  1.00 60.06
ATOM    342  CD1 TYR    40      20.304   9.004  51.501  1.00 61.58
ATOM    343  CE1 TYR    40      19.022   9.440  51.935  1.00 62.83
ATOM    344  CD2 TYR    40      21.378  10.323  53.226  1.00 61.08
ATOM    345  CE2 TYR    40      20.103  10.747  53.659  1.00 62.69
ATOM    346  CZ  TYR    40      18.909  10.329  53.020  1.00 62.88
ATOM    347  OH  TYR    40      17.671  10.840  53.422  1.00 61.77
ATOM    348  N   ARG    41      23.252  11.358  48.945  1.00 52.46
ATOM    349  CA  ARG    41      22.673  11.961  47.753  1.00 51.65
ATOM    350  C   ARG    41      23.716  12.942  47.196  1.00 50.92
ATOM    351  O   ARG    41      24.702  13.101  47.920  1.00 51.98
ATOM    352  CB  ARG    41      21.404  12.691  48.191  1.00 52.20
ATOM    353  CG  ARG    41      20.277  11.842  48.801  1.00 52.41
ATOM    354  CD  ARG    41      19.447  11.445  47.600  1.00 53.34
ATOM    355  NE  ARG    41      19.050  10.055  47.564  1.00 53.39
ATOM    356  CZ  ARG    41      18.132   9.561  48.377  1.00 53.75
ATOM    357  NH1 ARG    41      17.497  10.284  49.304  1.00 53.88
ATOM    358  NH2 ARG    41      17.823   8.290  48.214  1.00 54.36
ATOM    359  N   SER    42      23.681  13.664  46.056  1.00 49.41
ATOM    360  CA  SER    42      24.795  14.540  45.661  1.00 48.87
ATOM    361  C   SER    42      24.404  15.791  44.885  1.00 48.49
ATOM    362  O   SER    42      23.219  16.051  45.039  1.00 49.44
ATOM    363  CB  SER    42      25.766  13.736  44.828  1.00 49.14
ATOM    364  OG  SER    42      26.179  12.560  45.506  1.00 49.12
ATOM    365  N   GLY    43      25.183  16.661  44.152  1.00 47.95
ATOM    366  CA  GLY    43      24.572  17.651  43.224  1.00 46.17
ATOM    367  C   GLY    43      25.316  18.577  42.212  1.00 45.06
ATOM    368  O   GLY    43      26.460  18.997  42.322  1.00 44.80
ATOM    369  N   LYS    44      24.648  18.861  41.080  1.00 44.11
ATOM    370  CA  LYS    44      24.914  20.061  40.275  1.00 41.56
ATOM    371  C   LYS    44      23.607  20.865  40.417  1.00 40.77
ATOM    372  O   LYS    44      23.443  21.963  39.857  1.00 38.84
ATOM    373  CB  LYS    44      25.155  19.821  38.782  1.00 41.35
ATOM    374  CG  LYS    44      25.484  21.184  38.091  1.00 41.32
ATOM    375  CD  LYS    44      26.260  21.157  36.802  1.00 41.44
ATOM    376  CE  LYS    44      25.727  20.024  35.966  1.00 41.88
ATOM    377  NZ  LYS    44      26.307  20.041  34.647  1.00 43.13
ATOM    378  N   ALA    45      22.702  20.350  41.293  1.00 40.15
ATOM    379  CA  ALA    45      21.483  21.010  41.684  1.00 40.89
ATOM    380  C   ALA    45      20.661  21.574  40.491  1.00 41.70
ATOM    381  O   ALA    45      20.647  21.011  39.394  1.00 41.61
ATOM    382  CB  ALA    45      21.914  22.089  42.664  1.00 39.21
ATOM    383  N   CYS    46      20.005  22.723  40.630  1.00 42.03
ATOM    384  CA  CYS    46      19.186  23.347  39.620  1.00 41.11
ATOM    385  CB  CYS    46      18.224  24.197  40.423  1.00 39.73
ATOM    386  SG  CYS    46      17.480  23.154  41.716  1.00 39.61
ATOM    387  C   CYS    46      20.103  24.120  38.681  1.00 42.26
ATOM    388  O   CYS    46      19.682  24.861  37.803  1.00 42.46
ATOM    389  N   ASN    47      21.410  23.992  38.856  1.00 43.73
ATOM    390  CA  ASN    47      22.411  24.689  38.080  1.00 45.60
ATOM    391  C   ASN    47      22.180  26.186  37.941  1.00 45.83
ATOM    392  O   ASN    47      22.439  26.851  36.926  1.00 46.77
ATOM    393  CB  ASN    47      22.530  24.075  36.680  1.00 46.79
ATOM    394  CG  ASN    47      23.969  24.190  36.185  1.00 47.51
ATOM    395  OD1 ASN    47      24.742  25.114  36.485  1.00 48.75
ATOM    396  ND2 ASN    47      24.410  23.208  35.425  1.00 48.28
ATOM    397  N   HIS    48      21.743  26.769  39.051  1.00 45.73
ATOM    398  CA  HIS    48      21.520  28.203  39.089  1.00 44.93
ATOM    399  C   HIS    48      22.832  28.964  38.925  1.00 44.45
ATOM    400  O   HIS    48      22.749  30.145  38.618  1.00 45.11
ATOM    401  CB  HIS    48      20.847  28.590  40.417  1.00 44.07
ATOM    402  CG  HIS    48      20.673  30.085  40.682  1.00 43.14
ATOM    403  CD2 HIS    48      21.561  30.814  41.436  1.00 42.74
ATOM    404  ND1 HIS    48      19.713  30.916  40.295  1.00 42.89
ATOM    405  CE1 HIS    48      19.976  32.102  40.781  1.00 42.85
ATOM    406  NE2 HIS    48      21.089  32.020  41.457  1.00 42.75
ATOM    407  N   TRP    49      24.027  28.408  39.105  1.00 44.29
ATOM    408  CA  TRP    49      25.247  29.205  38.953  1.00 44.56
ATOM    409  C   TRP    49      25.424  29.607  37.498  1.00 44.31
ATOM    410  O   TRP    49      25.761  30.751  37.211  1.00 42.75
ATOM    411  CB  TRP    49      26.473  28.405  39.431  1.00 45.00
ATOM    412  CG  TRP    49      27.672  29.252  39.849  1.00 45.17
ATOM    413  CD2 TRP    49      27.708  30.290  40.758  1.00 44.82
ATOM    414  CE2 TRP    49      29.049  30.652  40.708  1.00 44.65
ATOM    415  CE3 TRP    49      26.851  30.985  41.597  1.00 44.91
ATOM    416  CD1 TRP    49      28.895  29.002  39.294  1.00 45.39
ATOM    417  NE1 TRP    49      29.701  29.876  39.844  1.00 45.24
ATOM    418  CZ2 TRP    49      29.565  31.681  41.473  1.00 44.45
ATOM    419  CZ3 TRP    49      27.364  32.024  42.368  1.00 45.03
ATOM    420  CH2 TRP    49      28.712  32.375  42.311  1.00 44.66
ATOM    421  N   GLU    50      25.142  28.690  36.572  1.00 44.74
ATOM    422  CA  GLU    50      25.199  29.096  35.204  1.00 46.03
ATOM    423  C   GLU    50      23.857  29.657  34.767  1.00 45.56
ATOM    424  O   GLU    50      23.823  30.704  34.106  1.00 45.33
ATOM    425  CB  GLU    50      25.632  27.916  34.374  1.00 48.02
ATOM    426  CG  GLU    50      27.138  28.086  33.971  1.00 51.27
ATOM    427  CD  GLU    50      28.261  28.045  35.041  1.00 52.99
ATOM    428  OE1 GLU    50      28.953  29.049  35.260  1.00 53.37
ATOM    429  OE2 GLU    50      28.477  26.990  35.653  1.00 54.77
ATOM    430  N   LEU    51      22.696  29.113  35.152  1.00 44.90
ATOM    431  CA  LEU    51      21.430  29.672  34.661  1.00 43.90
ATOM    432  C   LEU    51      20.878  30.815  35.481  1.00 43.99
ATOM    433  O   LEU    51      19.717  31.169  35.264  1.00 44.69
ATOM    434  CB  LEU    51      20.317  28.630  34.596  1.00 42.70
ATOM    435  CG  LEU    51      20.600  27.268  34.034  1.00 42.77
ATOM    436  CD1 LEU    51      19.280  26.566  33.879  1.00 42.49
ATOM    437  CD2 LEU    51      21.304  27.348  32.691  1.00 42.58
ATOM    438  N   TYR    52      21.600  31.503  36.363  1.00 44.04
ATOM    439  CA  TYR    52      20.967  32.455  37.269  1.00 44.25
ATOM    440  C   TYR    52      20.194  33.545  36.589  1.00 44.13
ATOM    441  O   TYR    52      19.215  34.001  37.157  1.00 44.71
ATOM    442  CB  TYR    52      21.964  33.161  38.217  1.00 44.48
ATOM    443  CG  TYR    52      23.062  33.981  37.543  1.00 44.65
ATOM    444  CD1 TYR    52      24.135  33.260  37.031  1.00 44.41
ATOM    445  CE1 TYR    52      25.167  33.917  36.409  1.00 43.83
ATOM    446  CD2 TYR    52      23.024  35.392  37.437  1.00 44.07
ATOM    447  CE2 TYR    52      24.078  36.056  36.811  1.00 43.71
ATOM    448  CZ  TYR    52      25.129  35.291  36.313  1.00 43.69
ATOM    449  OH  TYR    52      26.208  35.851  35.699  1.00 44.09
ATOM    450  N   ARG    53      20.585  33.920  35.382  1.00 44.84
ATOM    451  CA  ARG    53      19.902  34.974  34.611  1.00 45.83
ATOM    452  C   ARG    53      18.492  34.611  34.147  1.00 43.32
ATOM    453  O   ARG    53      17.568  35.423  34.150  1.00 42.07
ATOM    454  CB  ARG    53      20.771  35.359  33.374  1.00 48.23
ATOM    455  CG  ARG    53      22.059  36.148  33.716  1.00 51.26
ATOM    456  CD  ARG    53      23.103  36.203  32.599  1.00 53.66
ATOM    457  NE  ARG    53      22.869  37.230  31.583  1.00 56.26
ATOM    458  CZ  ARG    53      21.983  37.146  30.545  1.00 57.79
ATOM    459  NH1 ARG    53      21.157  36.098  30.297  1.00 57.71
ATOM    460  NH2 ARG    53      21.998  38.138  29.639  1.00 58.38
ATOM    461  N   ASP    54      18.337  33.358  33.770  1.00 41.60
ATOM    462  CA  ASP    54      17.071  32.866  33.324  1.00 40.76
ATOM    463  C   ASP    54      16.165  32.794  34.529  1.00 39.76
ATOM    464  O   ASP    54      15.050  33.323  34.480  1.00 40.91
ATOM    465  CB  ASP    54      17.246  31.501  32.705  1.00 42.02
ATOM    466  CG  ASP    54      18.182  31.453  31.483  1.00 43.57
ATOM    467  OD1 ASP    54      18.742  30.368  31.209  1.00 44.31
ATOM    468  OD2 ASP    54      18.343  32.481  30.805  1.00 43.61
ATOM    469  N   ASP    55      16.608  32.232  35.651  1.00 37.75
ATOM    470  CA  ASP    55      15.755  32.152  36.818  1.00 35.59
ATOM    471  C   ASP    55      15.360  33.535  37.287  1.00 34.51
ATOM    472  O   ASP    55      14.225  33.726  37.713  1.00 33.71
ATOM    473  CB  ASP    55      16.453  31.466  37.962  1.00 36.16
ATOM    474  CG  ASP    55      16.970  30.065  37.714  1.00 36.86
ATOM    475  OD1 ASP    55      16.352  29.355  36.930  1.00 37.74
ATOM    476  OD2 ASP    55      17.974  29.668  38.314  1.00 36.95
ATOM    477  N   ILE    56      16.238  34.528  37.215  1.00 33.85
ATOM    478  CA  ILE    56      15.865  35.840  37.709  1.00 35.65
ATOM    479  C   ILE    56      14.773  36.479  36.838  1.00 36.99
ATOM    480  O   ILE    56      13.792  36.984  37.389  1.00 36.72
ATOM    481  CB  ILE    56      17.170  36.725  37.823  1.00 35.02
ATOM    482  CG2 ILE    56      16.860  38.228  37.895  1.00 34.30
ATOM    483  CG1 ILE    56      17.925  36.263  39.096  1.00 34.53
ATOM    484  CD1 ILE    56      19.262  36.980  39.312  1.00 33.77
ATOM    485  N   GLN    57      14.883  36.432  35.502  1.00 38.45
ATOM    486  CA  GLN    57      13.828  36.920  34.625  1.00 39.37
ATOM    487  C   GLN    57      12.550  36.138  34.897  1.00 37.69
ATOM    488  O   GLN    57      11.501  36.769  35.076  1.00 37.33
ATOM    489  CB  GLN    57      14.189  36.753  33.146  1.00 42.29
ATOM    490  CG  GLN    57      14.755  37.973  32.411  1.00 45.09
ATOM    491  CD  GLN    57      16.079  38.557  32.924  1.00 47.43
ATOM    492  OE1 GLN    57      16.164  39.769  33.137  1.00 49.01
ATOM    493  NE2 GLN    57      17.191  37.838  33.116  1.00 47.84
ATOM    494  N   LEU    58      12.570  34.809  35.017  1.00 35.68
ATOM    495  CA  LEU    58      11.346  34.064  35.309  1.00 35.63
ATOM    496  C   LEU    58      10.669  34.538  36.606  1.00 36.43
ATOM    497  O   LEU    58       9.450  34.726  36.736  1.00 37.42
ATOM    498  CB  LEU    58      11.714  32.599  35.374  1.00 34.16
ATOM    499  CG  LEU    58      10.637  31.596  35.647  1.00 33.65
ATOM    500  CD1 LEU    58       9.525  31.731  34.629  1.00 33.31
ATOM    501  CD2 LEU    58      11.248  30.215  35.618  1.00 33.02
ATOM    502  N   MET    59      11.524  34.881  37.554  1.00 37.12
ATOM    503  CA  MET    59      11.141  35.388  38.848  1.00 36.99
ATOM    504  C   MET    59      10.383  36.717  38.738  1.00 37.18
ATOM    505  O   MET    59       9.365  36.982  39.395  1.00 36.59
ATOM    506  CB  MET    59      12.468  35.458  39.580  1.00 36.60
ATOM    507  CG  MET    59      12.491  36.098  40.936  1.00 35.79
ATOM    508  SD  MET    59      14.036  35.713  41.763  1.00 35.30
ATOM    509  CE  MET    59      14.244  33.954  41.702  1.00 33.28
ATOM    510  N   THR    60      10.895  37.584  37.872  1.00 37.85
ATOM    511  CA  THR    60      10.261  38.862  37.618  1.00 37.80
ATOM    512  C   THR    60       9.019  38.610  36.786  1.00 36.78
ATOM    513  O   THR    60       8.040  39.286  37.052  1.00 37.75
ATOM    514  CB  THR    60      11.192  39.815  36.842  1.00 38.44
ATOM    515  OG1 THR    60      12.559  39.577  37.232  1.00 39.00
ATOM    516  CG2 THR    60      10.776  41.263  37.129  1.00 38.78
ATOM    517  N   SER    61       8.949  37.659  35.853  1.00 35.33
ATOM    518  CA  SER    61       7.750  37.481  35.077  1.00 34.83
ATOM    519  C   SER    61       6.593  36.971  35.875  1.00 34.43
ATOM    520  O   SER    61       5.459  37.313  35.542  1.00 35.73
ATOM    521  CB  SER    61       7.979  36.536  33.945  1.00 35.56
ATOM    522  OG  SER    61       8.568  37.210  32.826  1.00 37.38
ATOM    523  N   LEU    62       6.827  36.186  36.933  1.00 33.10
ATOM    524  CA  LEU    62       5.726  35.740  37.766  1.00 31.24
ATOM    525  C   LEU    62       5.304  36.847  38.726  1.00 30.27
ATOM    526  O   LEU    62       4.315  36.693  39.440  1.00 31.21
ATOM    527  CB  LEU    62       6.167  34.489  38.498  1.00 31.14
ATOM    528  CG  LEU    62       6.656  33.359  37.593  1.00 31.90
ATOM    529  CD1 LEU    62       7.290  32.248  38.407  1.00 32.34
ATOM    530  CD2 LEU    62       5.489  32.735  36.861  1.00 31.71
ATOM    531  N   GLY    63       5.999  37.989  38.796  1.00 28.97
ATOM    532  CA  GLY    63       5.609  39.127  39.653  1.00 28.47
ATOM    533  C   GLY    63       5.925  39.064  41.166  1.00 27.25
ATOM    534  O   GLY    63       5.215  39.697  41.943  1.00 27.23
ATOM    535  N   TYR    64       7.011  38.372  41.600  1.00 27.15
ATOM    536  CA  TYR    64       7.514  38.225  42.990  1.00 25.15
ATOM    537  C   TYR    64       8.327  39.454  43.224  1.00 24.22
ATOM    538  O   TYR    64       9.173  39.746  42.384  1.00 23.09
ATOM    539  CB  TYR    64       8.446  37.025  43.144  1.00 24.74
ATOM    540  CG  TYR    64       7.829  35.701  42.720  1.00 25.00
ATOM    541  CD1 TYR    64       8.593  34.748  42.063  1.00 25.22
ATOM    542  CE1 TYR    64       8.001  33.548  41.679  1.00 25.90
ATOM    543  CD2 TYR    64       6.477  35.452  42.990  1.00 25.53
ATOM    544  CE2 TYR    64       5.870  34.265  42.607  1.00 25.42
ATOM    545  CZ  TYR    64       6.635  33.322  41.949  1.00 26.35
ATOM    546  OH  TYR    64       5.982  32.190  41.477  1.00 27.60
ATOM    547  N   ASN    65       8.150  40.186  44.297  1.00 24.17
ATOM    548  CA  ASN    65       8.923  41.405  44.457  1.00 25.32
ATOM    549  C   ASN    65      10.077  41.268  45.464  1.00 25.73
ATOM    550  O   ASN    65      10.625  42.277  45.930  1.00 26.73
ATOM    551  CB  ASN    65       8.003  42.539  44.909  1.00 26.36
ATOM    552  CG  ASN    65       7.355  42.356  46.277  1.00 27.79
ATOM    553  OD1 ASN    65       7.406  41.266  46.834  1.00 28.50
ATOM    554  ND2 ASN    65       6.732  43.338  46.940  1.00 28.98
ATOM    555  N   ALA    66      10.513  40.060  45.837  1.00 24.61
ATOM    556  CA  ALA    66      11.542  39.827  46.838  1.00 22.83
ATOM    557  C   ALA    66      12.108  38.460  46.540  1.00 23.09
ATOM    558  O   ALA    66      11.456  37.634  45.904  1.00 23.16
ATOM    559  CB  ALA    66      10.960  39.800  48.206  1.00 21.26
ATOM    560  N   TYR    67      13.370  38.227  46.857  1.00 23.80
ATOM    561  CA  TYR    67      14.023  36.931  46.688  1.00 23.41
ATOM    562  C   TYR    67      15.018  36.797  47.846  1.00 23.64
ATOM    563  O   TYR    67      15.818  37.699  48.124  1.00 23.46
ATOM    564  CB  TYR    67      14.760  36.878  45.345  1.00 22.48
ATOM    565  CG  TYR    67      15.590  35.621  45.108  1.00 21.88
ATOM    566  CD1 TYR    67      16.887  35.817  44.655  1.00 22.21
ATOM    567  CE1 TYR    67      17.706  34.722  44.419  1.00 22.21
ATOM    568  CD2 TYR    67      15.105  34.316  45.328  1.00 21.98
ATOM    569  CE2 TYR    67      15.918  33.208  45.095  1.00 21.50
ATOM    570  CZ  TYR    67      17.218  33.444  44.637  1.00 22.41
ATOM    571  OH  TYR    67      18.097  32.408  44.371  1.00 22.94
ATOM    572  N   ARG    68      14.945  35.716  48.588  1.00 24.31
ATOM    573  CA  ARG    68      15.895  35.508  49.646  1.00 25.91
ATOM    574  C   ARG    68      16.821  34.402  49.178  1.00 26.18
ATOM    575  O   ARG    68      16.378  33.334  48.706  1.00 26.05
ATOM    576  CB  ARG    68      15.117  35.168  50.937  1.00 25.72
ATOM    577  CG  ARG    68      15.538  34.050  51.824  1.00 25.78
ATOM    578  CD  ARG    68      15.982  34.537  53.139  1.00 28.43
ATOM    579  NE  ARG    68      15.693  33.506  54.136  1.00 31.12
ATOM    580  CZ  ARG    68      16.409  32.385  54.311  1.00 31.53
ATOM    581  NH1 ARG    68      17.492  32.089  53.573  1.00 34.29
ATOM    582  NH2 ARG    68      16.022  31.518  55.217  1.00 31.32
ATOM    583  N   PHE    69      18.115  34.666  49.327  1.00 25.92
ATOM    584  CA  PHE    69      19.123  33.688  48.912  1.00 26.86
ATOM    585  C   PHE    69      20.392  33.786  49.758  1.00 27.70
ATOM    586  O   PHE    69      20.608  34.812  50.403  1.00 27.67
ATOM    587  CB  PHE    69      19.522  33.891  47.427  1.00 23.88
ATOM    588  CG  PHE    69      20.243  35.198  47.159  1.00 21.34
ATOM    589  CD1 PHE    69      21.611  35.180  46.897  1.00 19.57
ATOM    590  CD2 PHE    69      19.543  36.411  47.209  1.00 20.01
ATOM    591  CE1 PHE    69      22.283  36.390  46.691  1.00 18.63
ATOM    592  CE2 PHE    69      20.251  37.596  47.003  1.00 19.84
ATOM    593  CZ  PHE    69      21.623  37.597  46.745  1.00 17.15
ATOM    594  N   SER    70      21.292  32.814  49.743  1.00 29.30
ATOM    595  CA  SER    70      22.486  32.964  50.521  1.00 29.70
ATOM    596  C   SER    70      23.758  33.010  49.704  1.00 30.62
ATOM    597  O   SER    70      23.886  32.347  48.650  1.00 30.57
ATOM    598  CB  SER    70      22.566  31.837  51.509  1.00 30.59
ATOM    599  OG  SER    70      22.682  30.552  50.919  1.00 32.10
ATOM    600  N   ILE    71      24.719  33.780  50.239  1.00 30.43
ATOM    601  CA  ILE    71      26.037  33.814  49.644  1.00 29.29
ATOM    602  C   ILE    71      26.687  32.521  50.047  1.00 28.81
ATOM    603  O   ILE    71      26.363  31.995  51.104  1.00 27.68
ATOM    604  CB  ILE    71      26.762  34.990  50.201  1.00 29.44
ATOM    605  CG2 ILE    71      28.282  34.951  50.018  1.00 30.16
ATOM    606  CG1 ILE    71      26.196  36.144  49.456  1.00 30.07
ATOM    607  CD1 ILE    71      26.631  37.403  50.180  1.00 31.39
ATOM    608  N   GLU    72      27.528  31.950  49.201  1.00 29.72
ATOM    609  CA  GLU    72      28.271  30.775  49.593  1.00 31.24
ATOM    610  C   GLU    72      29.719  31.165  49.983  1.00 32.09
ATOM    611  O   GLU    72      30.590  31.416  49.139  1.00 31.58
ATOM    612  CB  GLU    72      28.210  29.811  48.421  1.00 31.44
ATOM    613  CG  GLU    72      28.918  28.501  48.600  1.00 32.16
ATOM    614  CD  GLU    72      28.231  27.524  49.534  1.00 33.19
ATOM    615  OE1 GLU    72      27.070  27.723  49.894  1.00 34.15
ATOM    616  OE2 GLU    72      28.870  26.536  49.893  1.00 33.18
ATOM    617  N   TRP    73      30.038  31.169  51.285  1.00 33.25
ATOM    618  CA  TRP    73      31.354  31.511  51.805  1.00 33.93
ATOM    619  C   TRP    73      32.482  30.720  51.176  1.00 34.62
ATOM    620  O   TRP    73      33.530  31.312  50.904  1.00 34.50
ATOM    621  CB  TRP    73      31.302  31.300  53.299  1.00 34.46
ATOM    622  CG  TRP    73      32.496  31.620  54.213  1.00 34.56
ATOM    623  CD2 TRP    73      32.505  31.250  55.530  1.00 33.59
ATOM    624  CE2 TRP    73      33.787  31.641  55.917  1.00 33.74
ATOM    625  CE3 TRP    73      31.623  30.643  56.426  1.00 33.52
ATOM    626  CD1 TRP    73      33.680  32.216  53.806  1.00 34.20
ATOM    627  NE1 TRP    73      34.427  32.199  54.867  1.00 33.69
ATOM    628  CZ2 TRP    73      34.214  31.418  57.233  1.00 32.71
ATOM    629  CZ3 TRP    73      32.043  30.421  57.736  1.00 33.07
ATOM    630  CH2 TRP    73      33.330  30.812  58.128  1.00 32.96
ATOM    631  N   SER    74      32.313  29.427  50.874  1.00 35.65
ATOM    632  CA  SER    74      33.408  28.704  50.246  1.00 36.53
ATOM    633  C   SER    74      33.597  28.993  48.761  1.00 37.55
ATOM    634  O   SER    74      34.550  28.505  48.128  1.00 38.14
ATOM    635  CB  SER    74      33.218  27.220  50.462  1.00 35.87
ATOM    636  OG  SER    74      32.104  26.564  49.877  1.00 37.02
ATOM    637  N   ARG    75      32.698  29.755  48.139  1.00 37.76
ATOM    638  CA  ARG    75      32.967  30.116  46.769  1.00 38.43
ATOM    639  C   ARG    75      33.973  31.225  46.805  1.00 38.55
ATOM    640  O   ARG    75      34.859  31.261  45.966  1.00 39.74
ATOM    641  CB  ARG    75      31.761  30.637  46.039  1.00 39.64
ATOM    642  CG  ARG    75      30.784  29.536  45.687  1.00 41.31
ATOM    643  CD  ARG    75      29.875  30.041  44.579  1.00 42.13
ATOM    644  NE  ARG    75      29.008  28.956  44.176  1.00 43.61
ATOM    645  CZ  ARG    75      29.250  28.136  43.154  1.00 43.69
ATOM    646  NH1 ARG    75      28.380  27.161  42.893  1.00 44.19
ATOM    647  NH2 ARG    75      30.317  28.282  42.379  1.00 44.36
ATOM    648  N   LEU    76      33.821  32.096  47.801  1.00 38.53
ATOM    649  CA  LEU    76      34.595  33.308  48.023  1.00 38.03
ATOM    650  C   LEU    76      35.982  33.099  48.657  1.00 38.62
ATOM    651  O   LEU    76      36.915  33.893  48.525  1.00 38.45
ATOM    652  CB  LEU    76      33.656  34.161  48.859  1.00 37.12
ATOM    653  CG  LEU    76      33.048  35.452  48.372  1.00 36.53
ATOM    654  CD1 LEU    76      32.562  35.412  46.951  1.00 36.27
ATOM    655  CD2 LEU    76      31.891  35.703  49.270  1.00 36.61
ATOM    656  N   PHE    77      36.144  32.046  49.440  1.00 40.05
ATOM    657  CA  PHE    77      37.408  31.661  50.041  1.00 40.70
ATOM    658  C   PHE    77      37.386  30.130  49.985  1.00 41.28
ATOM    659  O   PHE    77      37.024  29.415  50.950  1.00 39.27
ATOM    660  CB  PHE    77      37.489  32.142  51.489  1.00 41.58
ATOM    661  CG  PHE    77      37.604  33.649  51.674  1.00 42.16
ATOM    662  CD1 PHE    77      38.878  34.230  51.770  1.00 42.87
ATOM    663  CD2 PHE    77      36.446  34.439  51.759  1.00 42.27
ATOM    664  CE1 PHE    77      38.983  35.612  51.953  1.00 43.25
ATOM    665  CE2 PHE    77      36.554  35.815  51.940  1.00 42.80
ATOM    666  CZ  PHE    77      37.819  36.402  52.035  1.00 43.31
ATOM    667  N   PRO    78      37.704  29.619  48.769  1.00 42.72
ATOM    668  CA  PRO    78      37.682  28.195  48.425  1.00 44.61
ATOM    669  C   PRO    78      38.604  27.480  49.384  1.00 47.38
ATOM    670  O   PRO    78      38.316  26.420  49.954  1.00 48.14
ATOM    671  CB  PRO    78      38.166  28.121  47.030  1.00 43.43
ATOM    672  CG  PRO    78      37.810  29.481  46.490  1.00 42.80
ATOM    673  CD  PRO    78      38.186  30.381  47.626  1.00 42.12
ATOM    674  N   GLU    79      39.741  28.150  49.554  1.00 50.40
ATOM    675  CA  GLU    79      40.700  27.730  50.511  1.00 52.71
ATOM    676  C   GLU    79      41.089  28.982  51.265  1.00 53.26
ATOM    677  O   GLU    79      41.088  30.090  50.755  1.00 52.40
ATOM    678  CB  GLU    79      41.874  27.083  49.791  1.00 54.02
ATOM    679  CG  GLU    79      42.731  27.942  48.880  1.00 55.96
ATOM    680  CD  GLU    79      43.960  27.234  48.293  1.00 57.52
ATOM    681  OE1 GLU    79      44.637  27.831  47.434  1.00 57.82
ATOM    682  OE2 GLU    79      44.227  26.087  48.690  1.00 58.30
ATOM    683  N   GLU    80      41.350  28.692  52.516  1.00 55.34
ATOM    684  CA  GLU    80      41.845  29.591  53.531  1.00 58.11
ATOM    685  C   GLU    80      41.971  31.085  53.223  1.00 59.09
ATOM    686  O   GLU    80      40.921  31.716  53.073  1.00 60.46
ATOM    687  CB  GLU    80      43.131  28.893  53.967  1.00 58.74
ATOM    688  CG  GLU    80      43.964  29.531  55.068  1.00 59.98
ATOM    689  CD  GLU    80      43.237  29.861  56.348  1.00 59.99
ATOM    690  OE1 GLU    80      42.712  30.979  56.435  1.00 60.32
ATOM    691  OE2 GLU    80      43.231  28.996  57.226  1.00 60.14
ATOM    692  N   ASN    81      43.104  31.763  53.079  1.00 59.97
ATOM    693  CA  ASN    81      43.013  33.187  52.780  1.00 60.45
ATOM    694  C   ASN    81      42.991  33.490  51.283  1.00 60.34
ATOM    695  O   ASN    81      43.124  34.652  50.854  1.00 60.73
ATOM    696  CB  ASN    81      44.166  33.923  53.472  1.00 60.74
ATOM    697  CG  ASN    81      43.617  34.670  54.680  1.00 60.96
ATOM    698  OD1 ASN    81      43.648  34.159  55.807  1.00 61.42
ATOM    699  ND2 ASN    81      43.055  35.867  54.502  1.00 60.54
ATOM    700  N   LYS    82      42.798  32.435  50.483  1.00 58.99
ATOM    701  CA  LYS    82      42.684  32.572  49.059  1.00 58.05
ATOM    702  C   LYS    82      41.275  33.033  48.646  1.00 57.04
ATOM    703  O   LYS    82      40.336  32.254  48.465  1.00 57.49
ATOM    704  CB  LYS    82      43.013  31.246  48.431  1.00 58.52
ATOM    705  CG  LYS    82      44.403  31.172  47.871  1.00 59.88
ATOM    706  CD  LYS    82      44.649  32.212  46.763  1.00 60.77
ATOM    707  CE  LYS    82      46.064  32.111  46.189  1.00 61.40
ATOM    708  NZ  LYS    82      46.308  30.783  45.635  1.00 61.81
ATOM    709  N   PHE    83      41.102  34.341  48.536  1.00 55.36
ATOM    710  CA  PHE    83      39.866  34.950  48.086  1.00 53.82
ATOM    711  C   PHE    83      39.635  34.632  46.630  1.00 53.57
ATOM    712  O   PHE    83      40.595  34.522  45.856  1.00 53.96
ATOM    713  CB  PHE    83      39.956  36.439  48.244  1.00 53.11
ATOM    714  CG  PHE    83      38.746  37.231  47.805  1.00 52.55
ATOM    715  CD1 PHE    83      38.943  38.346  46.991  1.00 52.42
ATOM    716  CD2 PHE    83      37.461  36.862  48.216  1.00 52.45
ATOM    717  CE1 PHE    83      37.845  39.099  46.582  1.00 52.48
ATOM    718  CE2 PHE    83      36.371  37.617  47.802  1.00 52.22
ATOM    719  CZ  PHE    83      36.563  38.733  46.986  1.00 52.41
ATOM    720  N   ASN    84      38.368  34.565  46.249  1.00 52.74
ATOM    721  CA  ASN    84      37.996  34.312  44.879  1.00 52.22
ATOM    722  C   ASN    84      37.242  35.513  44.346  1.00 52.46
ATOM    723  O   ASN    84      36.166  35.842  44.836  1.00 53.11
ATOM    724  CB  ASN    84      37.151  33.092  44.868  1.00 51.63
ATOM    725  CG  ASN    84      36.749  32.631  43.490  1.00 51.60
ATOM    726  OD1 ASN    84      36.659  33.395  42.520  1.00 51.94
ATOM    727  ND2 ASN    84      36.449  31.344  43.397  1.00 51.34
ATOM    728  N   GLU    85      37.715  36.207  43.324  1.00 52.96
ATOM    729  CA  GLU    85      37.033  37.400  42.841  1.00 53.88
ATOM    730  C   GLU    85      35.985  37.072  41.766  1.00 54.04
ATOM    731  O   GLU    85      35.089  37.887  41.485  1.00 53.88
ATOM    732  CB  GLU    85      38.082  38.365  42.291  1.00 54.99
ATOM    733  CG  GLU    85      37.616  39.743  41.790  1.00 56.01
ATOM    734  CD  GLU    85      37.631  40.879  42.799  1.00 57.14
ATOM    735  OE1 GLU    85      38.162  40.703  43.901  1.00 57.99
ATOM    736  OE2 GLU    85      37.125  41.959  42.474  1.00 57.59
ATOM    737  N   ASP    86      36.042  35.868  41.171  1.00 53.45
ATOM    738  CA  ASP    86      35.088  35.521  40.138  1.00 53.32
ATOM    739  C   ASP    86      33.706  35.400  40.746  1.00 52.30
ATOM    740  O   ASP    86      32.772  36.088  40.334  1.00 52.38
ATOM    741  CB  ASP    86      35.523  34.217  39.465  1.00 54.69
ATOM    742  CG  ASP    86      36.636  34.417  38.411  1.00 56.13
ATOM    743  OD1 ASP    86      37.537  33.571  38.320  1.00 56.83
ATOM    744  OD2 ASP    86      36.607  35.408  37.664  1.00 56.39
ATOM    745  N   ALA    87      33.611  34.623  41.825  1.00 51.25
ATOM    746  CA  ALA    87      32.380  34.446  42.576  1.00 49.83
ATOM    747  C   ALA    87      31.899  35.760  43.196  1.00 49.61
ATOM    748  O   ALA    87      30.703  36.069  43.210  1.00 50.11
ATOM    749  CB  ALA    87      32.627  33.416  43.656  1.00 49.36
ATOM    750  N   PHE    88      32.820  36.585  43.681  1.00 49.01
ATOM    751  CA  PHE    88      32.495  37.897  44.201  1.00 48.96
ATOM    752  C   PHE    88      31.774  38.743  43.150  1.00 50.52
ATOM    753  O   PHE    88      30.790  39.429  43.437  1.00 51.30
ATOM    754  CB  PHE    88      33.793  38.559  44.641  1.00 46.88
ATOM    755  CG  PHE    88      33.584  39.882  45.341  1.00 45.06
ATOM    756  CD1 PHE    88      33.398  39.906  46.726  1.00 44.82
ATOM    757  CD2 PHE    88      33.575  41.064  44.607  1.00 44.42
ATOM    758  CE1 PHE    88      33.204  41.122  47.376  1.00 44.39
ATOM    759  CE2 PHE    88      33.380  42.271  45.262  1.00 44.17
ATOM    760  CZ  PHE    88      33.196  42.306  46.643  1.00 43.98
ATOM    761  N   MET    89      32.219  38.723  41.897  1.00 52.54
ATOM    762  CA  MET    89      31.548  39.502  40.868  1.00 53.52
ATOM    763  C   MET    89      30.183  38.967  40.469  1.00 51.70
ATOM    764  O   MET    89      29.225  39.724  40.318  1.00 51.12
ATOM    765  CB  MET    89      32.447  39.601  39.630  1.00 56.69
ATOM    766  CG  MET    89      33.028  41.018  39.597  1.00 60.09
ATOM    767  SD  MET    89      31.743  42.219  40.107  1.00 63.87
ATOM    768  CE  MET    89      32.715  43.424  40.993  1.00 62.92
ATOM    769  N   LYS    90      30.093  37.641  40.380  1.00 49.61
ATOM    770  CA  LYS    90      28.891  36.924  40.001  1.00 47.84
ATOM    771  C   LYS    90      27.762  37.246  40.936  1.00 46.65
ATOM    772  O   LYS    90      26.683  37.620  40.507  1.00 46.22
ATOM    773  CB  LYS    90      29.174  35.466  40.051  1.00 48.28
ATOM    774  CG  LYS    90      28.043  34.630  39.578  1.00 49.31
ATOM    775  CD  LYS    90      28.539  34.017  38.294  1.00 51.01
ATOM    776  CE  LYS    90      27.796  32.699  38.118  1.00 52.05
ATOM    777  NZ  LYS    90      27.974  32.108  36.798  1.00 52.74
ATOM    778  N   TYR    91      28.007  37.104  42.235  1.00 45.95
ATOM    779  CA  TYR    91      27.020  37.424  43.252  1.00 44.77
ATOM    780  C   TYR    91      26.657  38.899  43.225  1.00 45.57
ATOM    781  O   TYR    91      25.509  39.230  43.521  1.00 45.87
ATOM    782  CB  TYR    91      27.534  37.090  44.651  1.00 43.09
ATOM    783  CG  TYR    91      27.504  35.622  45.029  1.00 41.13
ATOM    784  CD1 TYR    91      26.281  34.956  45.136  1.00 40.41
ATOM    785  CE1 TYR    91      26.248  33.616  45.519  1.00 39.63
ATOM    786  CD2 TYR    91      28.699  34.959  45.295  1.00 40.62
ATOM    787  CE2 TYR    91      28.674  33.624  45.679  1.00 39.99
ATOM    788  CZ  TYR    91      27.448  32.973  45.791  1.00 39.52
ATOM    789  OH  TYR    91      27.428  31.682  46.235  1.00 39.07
ATOM    790  N   ARG    92      27.565  39.817  42.865  1.00 46.33
ATOM    791  CA  ARG    92      27.202  41.220  42.807  1.00 46.90
ATOM    792  C   ARG    92      26.310  41.420  41.617  1.00 46.22
ATOM    793  O   ARG    92      25.396  42.229  41.650  1.00 45.79
ATOM    794  CB  ARG    92      28.434  42.103  42.673  1.00 48.35
ATOM    795  CG  ARG    92      27.960  43.560  42.717  1.00 50.45
ATOM    796  CD  ARG    92      28.251  44.290  41.405  1.00 52.64
ATOM    797  NE  ARG    92      28.278  43.397  40.245  1.00 54.10
ATOM    798  CZ  ARG    92      28.927  43.714  39.130  1.00 55.03
ATOM    799  NH1 ARG    92      29.585  44.885  39.002  1.00 55.48
ATOM    800  NH2 ARG    92      28.959  42.797  38.160  1.00 55.70
ATOM    801  N   GLU    93      26.599  40.688  40.553  1.00 46.49
ATOM    802  CA  GLU    93      25.798  40.687  39.346  1.00 47.08
ATOM    803  C   GLU    93      24.394  40.102  39.606  1.00 45.95
ATOM    804  O   GLU    93      23.421  40.714  39.118  1.00 47.34
ATOM    805  CB  GLU    93      26.549  39.899  38.301  1.00 48.27
ATOM    806  CG  GLU    93      25.781  39.593  37.029  1.00 49.77
ATOM    807  CD  GLU    93      26.491  38.611  36.107  1.00 50.73
ATOM    808  OE1 GLU    93      26.012  38.404  34.994  1.00 51.48
ATOM    809  OE2 GLU    93      27.510  38.027  36.481  1.00 51.14
ATOM    810  N   ILE    94      24.217  38.980  40.345  1.00 42.43
ATOM    811  CA  ILE    94      22.896  38.516  40.772  1.00 39.17
ATOM    812  C   ILE    94      22.146  39.637  41.490  1.00 37.68
ATOM    813  O   ILE    94      20.994  39.931  41.187  1.00 37.49
ATOM    814  CB  ILE    94      23.022  37.305  41.721  1.00 38.74
ATOM    815  CG2 ILE    94      21.708  36.966  42.422  1.00 37.41
ATOM    816  CG1 ILE    94      23.583  36.172  40.873  1.00 38.79
ATOM    817  CD1 ILE    94      23.389  34.734  41.422  1.00 39.29
ATOM    818  N   ILE    95      22.820  40.301  42.406  1.00 35.96
ATOM    819  CA  ILE    95      22.258  41.379  43.180  1.00 35.10
ATOM    820  C   ILE    95      21.858  42.509  42.248  1.00 34.68
ATOM    821  O   ILE    95      20.889  43.223  42.502  1.00 33.74
ATOM    822  CB  ILE    95      23.342  41.835  44.246  1.00 35.27
ATOM    823  CG2 ILE    95      22.797  42.986  45.091  1.00 34.68
ATOM    824  CG1 ILE    95      23.693  40.700  45.203  1.00 34.60
ATOM    825  CD1 ILE    95      24.905  40.942  46.109  1.00 34.20
ATOM    826  N   ASP    96      22.630  42.676  41.180  1.00 35.19
ATOM    827  CA  ASP    96      22.443  43.735  40.196  1.00 36.23
ATOM    828  C   ASP    96      21.175  43.658  39.375  1.00 36.04
ATOM    829  O   ASP    96      20.404  44.617  39.178  1.00 35.53
ATOM    830  CB  ASP    96      23.591  43.752  39.229  1.00 37.23
ATOM    831  CG  ASP    96      24.570  44.869  39.502  1.00 38.29
ATOM    832  OD1 ASP    96      24.328  45.704  40.391  1.00 38.15
ATOM    833  OD2 ASP    96      25.570  44.883  38.778  1.00 39.81
ATOM    834  N   LEU    97      21.064  42.431  38.891  1.00 34.82
ATOM    835  CA  LEU    97      19.885  41.951  38.265  1.00 34.16
ATOM    836  C   LEU    97      18.744  42.244  39.216  1.00 34.56
ATOM    837  O   LEU    97      18.116  43.273  39.007  1.00 35.44
ATOM    838  CB  LEU    97      20.145  40.491  38.022  1.00 33.26
ATOM    839  CG  LEU    97      20.552  40.156  36.613  1.00 32.58
ATOM    840  CD1 LEU    97      21.412  41.277  36.092  1.00 32.24
ATOM    841  CD2 LEU    97      21.169  38.767  36.571  1.00 32.21
ATOM    842  N   LEU    98      18.580  41.524  40.324  1.00 35.09
ATOM    843  CA  LEU    98      17.455  41.653  41.226  1.00 35.68
ATOM    844  C   LEU    98      17.004  43.067  41.422  1.00 36.67
ATOM    845  O   LEU    98      15.863  43.410  41.156  1.00 38.02
ATOM    846  CB  LEU    98      17.780  41.080  42.599  1.00 36.23
ATOM    847  CG  LEU    98      17.598  39.627  43.103  1.00 37.46
ATOM    848  CD1 LEU    98      16.938  38.793  42.033  1.00 38.10
ATOM    849  CD2 LEU    98      18.939  38.991  43.482  1.00 37.43
ATOM    850  N   LEU    99      17.931  43.937  41.729  1.00 37.92
ATOM    851  CA  LEU    99      17.594  45.303  42.016  1.00 39.10
ATOM    852  C   LEU    99      17.120  46.029  40.779  1.00 40.60
ATOM    853  O   LEU    99      16.045  46.639  40.877  1.00 41.38
ATOM    854  CB  LEU    99      18.786  46.022  42.589  1.00 38.26
ATOM    855  CG  LEU    99      19.264  45.596  43.940  1.00 38.06
ATOM    856  CD1 LEU    99      20.643  46.165  44.105  1.00 37.98
ATOM    857  CD2 LEU    99      18.309  46.052  45.037  1.00 38.09
ATOM    858  N   THR   100      17.818  45.940  39.633  1.00 41.62
ATOM    859  CA  THR   100      17.339  46.643  38.448  1.00 43.01
ATOM    860  C   THR   100      15.980  46.080  37.950  1.00 42.81
ATOM    861  O   THR   100      15.111  46.843  37.498  1.00 43.74
ATOM    862  CB  THR   100      18.447  46.592  37.337  1.00 43.33
ATOM    863  OG1 THR   100      18.787  45.240  37.107  1.00 44.58
ATOM    864  CG2 THR   100      19.709  47.333  37.736  1.00 43.50
ATOM    865  N   ARG   101      15.710  44.774  38.097  1.00 42.03
ATOM    866  CA  ARG   101      14.410  44.205  37.768  1.00 40.88
ATOM    867  C   ARG   101      13.431  44.440  38.934  1.00 39.19
ATOM    868  O   ARG   101      12.440  43.723  39.006  1.00 39.16
ATOM    869  CB  ARG   101      14.508  42.658  37.477  1.00 41.84
ATOM    870  CG  ARG   101      15.522  42.092  36.465  1.00 43.18
ATOM    871  CD  ARG   101      15.293  42.397  34.971  1.00 45.40
ATOM    872  NE  ARG   101      14.444  41.408  34.295  1.00 47.85
ATOM    873  CZ  ARG   101      13.765  41.600  33.123  1.00 48.91
ATOM    874  NH1 ARG   101      13.824  42.766  32.458  1.00 49.53
ATOM    875  NH2 ARG   101      12.989  40.613  32.606  1.00 48.38
ATOM    876  N   GLY   102      13.564  45.344  39.908  1.00 38.24
ATOM    877  CA  GLY   102      12.542  45.539  40.967  1.00 38.41
ATOM    878  C   GLY   102      12.322  44.480  42.109  1.00 38.19
ATOM    879  O   GLY   102      11.266  44.430  42.774  1.00 37.31
ATOM    880  N   ILE   103      13.325  43.647  42.412  1.00 38.20
ATOM    881  CA  ILE   103      13.241  42.553  43.379  1.00 37.55
ATOM    882  C   ILE   103      14.121  42.922  44.577  1.00 37.16
ATOM    883  O   ILE   103      15.327  43.147  44.349  1.00 38.20
ATOM    884  CB  ILE   103      13.770  41.242  42.759  1.00 37.65
ATOM    885  CG2 ILE   103      13.631  40.150  43.793  1.00 37.54
ATOM    886  CG1 ILE   103      13.022  40.903  41.467  1.00 38.31
ATOM    887  CD1 ILE   103      13.437  39.620  40.705  1.00 38.84
ATOM    888  N   THR   104      13.548  42.991  45.803  1.00 33.84
ATOM    889  CA  THR   104      14.287  43.216  47.040  1.00 31.12
ATOM    890  C   THR   104      15.094  42.004  47.524  1.00 30.88
ATOM    891  O   THR   104      14.501  40.939  47.785  1.00 31.58
ATOM    892  CB  THR   104      13.296  43.615  48.062  1.00 30.19
ATOM    893  OG1 THR   104      12.953  44.895  47.591  1.00 30.73
ATOM    894  CG2 THR   104      13.733  43.604  49.505  1.00 29.90
ATOM    895  N   PRO   105      16.424  42.038  47.650  1.00 29.78
ATOM    896  CA  PRO   105      17.145  40.945  48.286  1.00 28.32
ATOM    897  C   PRO   105      17.102  40.994  49.811  1.00 26.99
ATOM    898  O   PRO   105      16.986  42.066  50.425  1.00 26.97
ATOM    899  CB  PRO   105      18.547  41.053  47.722  1.00 28.24
ATOM    900  CG  PRO   105      18.352  41.859  46.463  1.00 28.80
ATOM    901  CD  PRO   105      17.339  42.901  46.904  1.00 28.68
ATOM    902  N   LEU   106      17.147  39.762  50.322  1.00 25.76
ATOM    903  CA  LEU   106      17.441  39.415  51.691  1.00 25.22
ATOM    904  C   LEU   106      18.403  38.217  51.555  1.00 25.27
ATOM    905  O   LEU   106      18.068  37.080  51.178  1.00 23.10
ATOM    906  CB  LEU   106      16.204  38.994  52.445  1.00 26.10
ATOM    907  CG  LEU   106      16.317  38.936  53.953  1.00 26.55
ATOM    908  CD1 LEU   106      14.898  38.963  54.460  1.00 26.56
ATOM    909  CD2 LEU   106      17.130  37.722  54.447  1.00 26.73
ATOM    910  N   VAL   107      19.658  38.551  51.888  1.00 26.35
ATOM    911  CA  VAL   107      20.825  37.656  51.778  1.00 26.46
ATOM    912  C   VAL   107      21.229  36.992  53.120  1.00 26.20
ATOM    913  O   VAL   107      21.318  37.652  54.148  1.00 27.11
ATOM    914  CB  VAL   107      21.999  38.435  51.244  1.00 26.02
ATOM    915  CG1 VAL   107      23.129  37.500  50.885  1.00 26.01
ATOM    916  CG2 VAL   107      21.529  39.223  50.049  1.00 26.83
ATOM    917  N   THR   108      21.434  35.680  53.170  1.00 25.04
ATOM    918  CA  THR   108      21.792  34.959  54.374  1.00 24.48
ATOM    919  C   THR   108      23.270  34.714  54.143  1.00 23.91
ATOM    920  O   THR   108      23.698  34.303  53.056  1.00 23.94
ATOM    921  CB  THR   108      21.004  33.616  54.487  1.00 23.57
ATOM    922  OG1 THR   108      19.681  33.988  54.206  1.00 24.45
ATOM    923  CG2 THR   108      20.746  33.062  55.865  1.00 21.90
ATOM    924  N   LEU   109      24.053  35.043  55.152  1.00 23.35
ATOM    925  CA  LEU   109      25.505  34.902  55.117  1.00 21.10
ATOM    926  C   LEU   109      25.936  33.449  55.307  1.00 20.23
ATOM    927  O   LEU   109      26.905  33.010  54.674  1.00 19.56
ATOM    928  CB  LEU   109      26.041  35.868  56.200  1.00 19.82
ATOM    929  CG  LEU   109      26.457  37.291  55.775  1.00 19.19
ATOM    930  CD1 LEU   109      25.959  37.640  54.404  1.00 19.15
ATOM    931  CD2 LEU   109      25.945  38.261  56.804  1.00 18.26
ATOM    932  N   HIS   110      25.231  32.650  56.101  1.00 19.69
ATOM    933  CA  HIS   110      25.603  31.268  56.313  1.00 19.55
ATOM    934  C   HIS   110      24.290  30.460  56.266  1.00 20.95
ATOM    935  O   HIS   110      23.382  30.778  57.045  1.00 20.08
ATOM    936  CB  HIS   110      26.259  31.171  57.678  1.00 17.82
ATOM    937  CG  HIS   110      26.803  29.788  57.998  1.00 17.18
ATOM    938  CD2 HIS   110      28.005  29.318  57.525  1.00 16.57
ATOM    939  ND1 HIS   110      26.263  28.803  58.749  1.00 17.04
ATOM    940  CE1 HIS   110      27.065  27.755  58.750  1.00 16.19
ATOM    941  NE2 HIS   110      28.102  28.094  58.008  1.00 17.05
ATOM    942  N   HIS   111      24.152  29.414  55.415  1.00 22.06
ATOM    943  CA  HIS   111      22.983  28.547  55.298  1.00 22.58
ATOM    944  C   HIS   111      23.498  27.114  55.227  1.00 23.06
ATOM    945  O   HIS   111      23.599  26.467  54.182  1.00 23.47
ATOM    946  CB  HIS   111      22.141  28.839  53.999  1.00 23.02
ATOM    947  CG  HIS   111      20.721  28.234  54.009  1.00 22.84
ATOM    948  CD2 HIS   111      20.428  26.870  54.097  1.00 22.94
ATOM    949  ND1 HIS   111      19.559  28.886  53.931  1.00 22.55
ATOM    950  CE1 HIS   111      18.603  27.973  53.964  1.00 23.58
ATOM    951  NE2 HIS   111      19.135  26.767  54.069  1.00 22.99
ATOM    952  N   PHE   112      23.733  26.624  56.430  1.00 24.23
ATOM    953  CA  PHE   112      24.279  25.314  56.755  1.00 25.59
ATOM    954  C   PHE   112      25.639  24.823  56.254  1.00 25.74
ATOM    955  O   PHE   112      26.167  23.877  56.855  1.00 25.48
ATOM    956  CB  PHE   112      23.204  24.252  56.401  1.00 26.30
ATOM    957  CG  PHE   112      21.856  24.467  57.111  1.00 27.91
ATOM    958  CD1 PHE   112      21.751  25.220  58.299  1.00 27.98
ATOM    959  CD2 PHE   112      20.690  23.896  56.576  1.00 28.76
ATOM    960  CE1 PHE   112      20.526  25.395  58.936  1.00 27.71
ATOM    961  CE2 PHE   112      19.456  24.075  57.227  1.00 28.93
ATOM    962  CZ  PHE   112      19.384  24.822  58.403  1.00 28.12
ATOM    963  N   THR   113      26.279  25.423  55.255  1.00 25.92
ATOM    964  CA  THR   113      27.462  24.847  54.666  1.00 26.20
ATOM    965  C   THR   113      28.588  25.828  54.888  1.00 27.70
ATOM    966  O   THR   113      28.470  27.030  54.602  1.00 28.16
ATOM    967  CB  THR   113      27.338  24.592  53.107  1.00 26.08
ATOM    968  OG1 THR   113      26.902  25.771  52.453  1.00 25.62
ATOM    969  CG2 THR   113      26.303  23.587  52.752  1.00 26.29
ATOM    970  N   SER   114      29.670  25.273  55.423  1.00 28.07
ATOM    971  CA  SER   114      30.896  25.999  55.709  1.00 27.05
ATOM    972  C   SER   114      32.021  25.496  54.774  1.00 27.11
ATOM    973  O   SER   114      31.906  24.365  54.229  1.00 27.03
ATOM    974  CB  SER   114      31.133  25.753  57.209  1.00 26.38
ATOM    975  OG  SER   114      29.905  25.968  57.942  1.00 24.03
ATOM    976  N   PRO   115      33.078  26.305  54.492  1.00 26.45
ATOM    977  CA  PRO   115      34.187  25.923  53.597  1.00 26.13
ATOM    978  C   PRO   115      34.829  24.660  54.112  1.00 26.47
ATOM    979  O   PRO   115      34.812  24.512  55.343  1.00 26.74
ATOM    980  CB  PRO   115      35.094  27.097  53.632  1.00 26.05
ATOM    981  CG  PRO   115      34.199  28.262  53.979  1.00 25.73
ATOM    982  CD  PRO   115      33.237  27.673  54.991  1.00 25.65
ATOM    983  N   LEU   116      35.406  23.733  53.358  1.00 26.99
ATOM    984  CA  LEU   116      35.943  22.514  53.993  1.00 28.89
ATOM    985  C   LEU   116      37.032  22.812  55.037  1.00 29.25
ATOM    986  O   LEU   116      37.051  22.305  56.151  1.00 29.61
ATOM    987  CB  LEU   116      36.572  21.593  52.980  1.00 29.91
ATOM    988  CG  LEU   116      36.259  20.106  53.053  1.00 31.36
ATOM    989  CD1 LEU   116      37.330  19.381  52.199  1.00 31.03
ATOM    990  CD2 LEU   116      36.211  19.602  54.499  1.00 31.29
ATOM    991  N   TRP   117      37.943  23.698  54.669  1.00 29.28
ATOM    992  CA  TRP   117      39.026  24.117  55.492  1.00 29.70
ATOM    993  C   TRP   117      38.624  24.647  56.847  1.00 31.98
ATOM    994  O   TRP   117      39.298  24.380  57.873  1.00 33.76
ATOM    995  CB  TRP   117      39.844  25.165  54.762  1.00 27.76
ATOM    996  CG  TRP   117      39.294  26.535  54.449  1.00 26.07
ATOM    997  CD2 TRP   117      39.276  27.653  55.237  1.00 26.65
ATOM    998  CE2 TRP   117      38.645  28.558  54.379  1.00 26.28
ATOM    999  CE3 TRP   117      39.676  28.071  56.518  1.00 27.08
ATOM   1000  CD1 TRP   117      38.760  26.730  53.238  1.00 25.96
ATOM   1001  NE1 TRP   117      38.375  27.971  53.225  1.00 26.47
ATOM   1002  CZ2 TRP   117      38.383  29.875  54.736  1.00 26.07
ATOM   1003  CZ3 TRP   117      39.418  29.395  56.889  1.00 27.01
ATOM   1004  CH2 TRP   117      38.775  30.286  56.005  1.00 26.73
ATOM   1005  N   PHE   118      37.476  25.329  56.863  1.00 32.04
ATOM   1006  CA  PHE   118      37.050  25.942  58.092  1.00 32.38
ATOM   1007  C   PHE   118      36.628  24.834  59.053  1.00 33.92
ATOM   1008  O   PHE   118      36.996  24.839  60.248  1.00 34.43
ATOM   1009  CB  PHE   118      35.955  26.900  57.710  1.00 31.37
ATOM   1010  CG  PHE   118      35.349  27.564  58.899  1.00 30.47
ATOM   1011  CD1 PHE   118      36.029  28.619  59.508  1.00 30.65
ATOM   1012  CD2 PHE   118      34.152  27.072  59.407  1.00 30.07
ATOM   1013  CE1 PHE   118      35.504  29.200  60.672  1.00 31.07
ATOM   1014  CE2 PHE   118      33.639  27.655  60.565  1.00 30.80
ATOM   1015  CZ  PHE   118      34.306  28.718  61.208  1.00 30.97
ATOM   1016  N   MET   119      35.961  23.817  58.483  1.00 35.39
ATOM   1017  CA  MET   119      35.465  22.683  59.256  1.00 37.37
ATOM   1018  C   MET   119      36.609  21.761  59.687  1.00 38.91
ATOM   1019  O   MET   119      36.604  21.202  60.792  1.00 39.00
ATOM   1020  CB  MET   119      34.433  21.951  58.411  1.00 37.82
ATOM   1021  CG  MET   119      33.130  22.752  58.381  1.00 38.66
ATOM   1022  SD  MET   119      32.383  23.022  60.015  1.00 39.76
ATOM   1023  CE  MET   119      31.679  21.413  60.180  1.00 38.66
ATOM   1024  N   LYS   120      37.635  21.642  58.824  1.00 39.84
ATOM   1025  CA  LYS   120      38.892  21.002  59.167  1.00 39.71
ATOM   1026  C   LYS   120      39.563  21.721  60.309  1.00 39.07
ATOM   1027  O   LYS   120      40.194  21.031  61.097  1.00 39.83
ATOM   1028  CB  LYS   120      39.821  20.995  58.001  1.00 40.24
ATOM   1029  CG  LYS   120      39.339  19.772  57.254  1.00 41.89
ATOM   1030  CD  LYS   120      40.018  19.614  55.917  1.00 43.56
ATOM   1031  CE  LYS   120      39.610  20.775  55.031  1.00 43.74
ATOM   1032  NZ  LYS   120      40.193  20.682  53.717  1.00 44.23
ATOM   1033  N   LYS   121      39.470  23.044  60.476  1.00 37.74
ATOM   1034  CA  LYS   121      39.965  23.636  61.703  1.00 36.50
ATOM   1035  C   LYS   121      39.008  23.448  62.875  1.00 35.60
ATOM   1036  O   LYS   121      39.241  24.054  63.929  1.00 35.56
ATOM   1037  CB  LYS   121      40.196  25.112  61.538  1.00 36.92
ATOM   1038  CG  LYS   121      41.420  25.329  60.709  1.00 37.38
ATOM   1039  CD  LYS   121      42.105  26.688  60.862  1.00 37.72
ATOM   1040  CE  LYS   121      43.249  26.705  59.819  1.00 38.75
ATOM   1041  NZ  LYS   121      44.152  25.539  59.862  1.00 39.22
ATOM   1042  N   GLY   122      37.918  22.662  62.779  1.00 34.12
ATOM   1043  CA  GLY   122      36.966  22.476  63.889  1.00 31.97
ATOM   1044  C   GLY   122      35.677  23.311  63.832  1.00 30.69
ATOM   1045  O   GLY   122      34.822  23.245  64.735  1.00 30.30
ATOM   1046  N   GLY   123      35.540  24.176  62.822  1.00 29.83
ATOM   1047  CA  GLY   123      34.314  24.920  62.601  1.00 28.84
ATOM   1048  C   GLY   123      34.028  25.987  63.634  1.00 29.03
ATOM   1049  O   GLY   123      34.913  26.757  63.975  1.00 29.47
ATOM   1050  N   PHE   124      32.793  26.093  64.126  1.00 28.97
ATOM   1051  CA  PHE   124      32.356  27.059  65.130  1.00 28.41
ATOM   1052  C   PHE   124      32.462  26.393  66.483  1.00 28.66
ATOM   1053  O   PHE   124      32.061  26.959  67.491  1.00 27.12
ATOM   1054  CB  PHE   124      30.894  27.492  64.902  1.00 27.69
ATOM   1055  CG  PHE   124      30.666  28.347  63.677  1.00 27.04
ATOM   1056  CD1 PHE   124      30.231  27.751  62.488  1.00 27.21
ATOM   1057  CD2 PHE   124      30.952  29.718  63.737  1.00 27.07
ATOM   1058  CE1 PHE   124      30.098  28.564  61.354  1.00 27.57
ATOM   1059  CE2 PHE   124      30.818  30.524  62.600  1.00 26.94
ATOM   1060  CZ  PHE   124      30.391  29.941  61.407  1.00 27.42
ATOM   1061  N   LEU   125      33.007  25.174  66.538  1.00 30.27
ATOM   1062  CA  LEU   125      33.311  24.529  67.806  1.00 32.17
ATOM   1063  C   LEU   125      34.467  25.230  68.499  1.00 33.55
ATOM   1064  O   LEU   125      34.607  25.101  69.699  1.00 34.79
ATOM   1065  CB  LEU   125      33.770  23.087  67.647  1.00 30.87
ATOM   1066  CG  LEU   125      33.021  22.009  68.373  1.00 29.74
ATOM   1067  CD1 LEU   125      33.724  20.743  68.026  1.00 30.56
ATOM   1068  CD2 LEU   125      32.967  22.208  69.865  1.00 29.13
ATOM   1069  N   ARG   126      35.297  25.994  67.795  1.00 36.18
ATOM   1070  CA  ARG   126      36.553  26.525  68.280  1.00 37.80
ATOM   1071  C   ARG   126      36.491  28.028  68.165  1.00 37.79
ATOM   1072  O   ARG   126      36.501  28.509  67.037  1.00 37.29
ATOM   1073  CB  ARG   126      37.548  25.869  67.373  1.00 39.51
ATOM   1074  CG  ARG   126      38.956  25.605  67.806  1.00 42.08
ATOM   1075  CD  ARG   126      39.119  24.160  67.431  1.00 43.43
ATOM   1076  NE  ARG   126      38.376  23.364  68.392  1.00 45.52
ATOM   1077  CZ  ARG   126      38.094  22.077  68.156  1.00 47.25
ATOM   1078  NH1 ARG   126      38.479  21.492  66.999  1.00 48.15
ATOM   1079  NH2 ARG   126      37.511  21.339  69.123  1.00 47.19
ATOM   1080  N   GLU   127      36.497  28.821  69.231  1.00 39.17
ATOM   1081  CA  GLU   127      36.330  30.271  69.113  1.00 41.48
ATOM   1082  C   GLU   127      37.391  31.066  68.350  1.00 41.47
ATOM   1083  O   GLU   127      37.206  32.208  67.926  1.00 40.96
ATOM   1084  CB  GLU   127      36.214  30.885  70.478  1.00 43.77
ATOM   1085  CG  GLU   127      35.396  32.179  70.376  1.00 47.44
ATOM   1086  CD  GLU   127      35.342  33.075  71.610  1.00 49.60
ATOM   1087  OE1 GLU   127      35.534  32.551  72.718  1.00 50.48
ATOM   1088  OE2 GLU   127      35.078  34.285  71.453  1.00 50.89
ATOM   1089  N   GLU   128      38.546  30.445  68.116  1.00 42.65
ATOM   1090  CA  GLU   128      39.639  31.053  67.354  1.00 42.16
ATOM   1091  C   GLU   128      39.141  31.275  65.951  1.00 39.31
ATOM   1092  O   GLU   128      39.273  32.348  65.393  1.00 38.16
ATOM   1093  CB  GLU   128      40.864  30.134  67.309  1.00 45.39
ATOM   1094  CG  GLU   128      41.533  29.951  68.658  1.00 49.69
ATOM   1095  CD  GLU   128      40.815  29.052  69.683  1.00 52.54
ATOM   1096  OE1 GLU   128      39.959  29.533  70.457  1.00 53.47
ATOM   1097  OE2 GLU   128      41.155  27.855  69.715  1.00 54.66
ATOM   1098  N   ASN   129      38.398  30.285  65.477  1.00 37.36
ATOM   1099  CA  ASN   129      37.882  30.233  64.134  1.00 35.94
ATOM   1100  C   ASN   129      36.962  31.359  63.722  1.00 34.22
ATOM   1101  O   ASN   129      36.799  31.636  62.517  1.00 33.89
ATOM   1102  CB  ASN   129      37.212  28.887  63.969  1.00 37.27
ATOM   1103  CG  ASN   129      38.238  27.762  63.958  1.00 37.96
ATOM   1104  OD1 ASN   129      39.393  28.044  63.635  1.00 39.17
ATOM   1105  ND2 ASN   129      37.942  26.497  64.267  1.00 37.67
ATOM   1106  N   LEU   130      36.462  32.092  64.712  1.00 32.26
ATOM   1107  CA  LEU   130      35.677  33.277  64.472  1.00 31.64
ATOM   1108  C   LEU   130      36.517  34.377  63.850  1.00 32.20
ATOM   1109  O   LEU   130      35.937  35.328  63.316  1.00 31.95
ATOM   1110  CB  LEU   130      35.071  33.759  65.761  1.00 31.60
ATOM   1111  CG  LEU   130      33.634  33.429  66.090  1.00 30.95
ATOM   1112  CD1 LEU   130      33.348  32.005  65.833  1.00 31.37
ATOM   1113  CD2 LEU   130      33.396  33.652  67.561  1.00 31.57
ATOM   1114  N   LYS   131      37.867  34.292  63.844  1.00 33.19
ATOM   1115  CA  LYS   131      38.716  35.222  63.076  1.00 33.48
ATOM   1116  C   LYS   131      38.478  35.032  61.586  1.00 33.27
ATOM   1117  O   LYS   131      38.654  35.942  60.778  1.00 33.16
ATOM   1118  CB  LYS   131      40.212  35.004  63.326  1.00 33.99
ATOM   1119  CG  LYS   131      40.704  33.611  63.091  1.00 35.37
ATOM   1120  CD  LYS   131      41.975  33.341  63.878  1.00 37.06
ATOM   1121  CE  LYS   131      43.228  33.511  63.018  1.00 38.22
ATOM   1122  NZ  LYS   131      43.425  34.899  62.616  1.00 39.49
ATOM   1123  N   HIS   132      38.057  33.813  61.212  1.00 32.25
ATOM   1124  CA  HIS   132      37.775  33.460  59.832  1.00 30.93
ATOM   1125  C   HIS   132      36.427  33.986  59.352  1.00 30.00
ATOM   1126  O   HIS   132      36.271  34.578  58.279  1.00 28.81
ATOM   1127  CB  HIS   132      37.880  31.967  59.774  1.00 31.11
ATOM   1128  CG  HIS   132      39.316  31.472  59.878  1.00 30.85
ATOM   1129  CD2 HIS   132      39.656  30.321  60.547  1.00 31.09
ATOM   1130  ND1 HIS   132      40.432  32.007  59.372  1.00 30.61
ATOM   1131  CE1 HIS   132      41.413  31.218  59.716  1.00 31.17
ATOM   1132  NE2 HIS   132      40.942  30.209  60.418  1.00 31.35
ATOM   1133  N   TRP   133      35.475  33.828  60.249  1.00 29.58
ATOM   1134  CA  TRP   133      34.158  34.356  60.029  1.00 31.47
ATOM   1135  C   TRP   133      34.264  35.856  59.831  1.00 32.91
ATOM   1136  O   TRP   133      33.734  36.376  58.858  1.00 34.72
ATOM   1137  CB  TRP   133      33.319  34.025  61.223  1.00 31.03
ATOM   1138  CG  TRP   133      31.986  34.712  61.264  1.00 31.41
ATOM   1139  CD2 TRP   133      30.907  34.389  60.479  1.00 32.29
ATOM   1140  CE2 TRP   133      29.934  35.273  60.991  1.00 32.21
ATOM   1141  CE3 TRP   133      30.605  33.484  59.441  1.00 32.61
ATOM   1142  CD1 TRP   133      31.736  35.707  62.171  1.00 31.38
ATOM   1143  NE1 TRP   133      30.478  36.022  61.984  1.00 31.42
ATOM   1144  CZ2 TRP   133      28.631  35.259  60.458  1.00 32.61
ATOM   1145  CZ3 TRP   133      29.310  33.473  58.920  1.00 32.60
ATOM   1146  CH2 TRP   133      28.339  34.351  59.427  1.00 32.86
ATOM   1147  N   GLU   134      34.976  36.553  60.709  1.00 33.71
ATOM   1148  CA  GLU   134      35.229  37.975  60.646  1.00 33.39
ATOM   1149  C   GLU   134      35.815  38.460  59.312  1.00 35.05
ATOM   1150  O   GLU   134      35.413  39.539  58.859  1.00 35.64
ATOM   1151  CB  GLU   134      36.149  38.233  61.811  1.00 32.82
ATOM   1152  CG  GLU   134      36.204  39.619  62.416  1.00 31.11
ATOM   1153  CD  GLU   134      36.832  40.739  61.612  1.00 30.67
ATOM   1154  OE1 GLU   134      37.774  40.498  60.850  1.00 29.73
ATOM   1155  OE2 GLU   134      36.361  41.871  61.774  1.00 31.26
ATOM   1156  N   LYS   135      36.761  37.736  58.650  1.00 36.76
ATOM   1157  CA  LYS   135      37.403  38.138  57.380  1.00 37.41
ATOM   1158  C   LYS   135      36.348  38.132  56.318  1.00 36.95
ATOM   1159  O   LYS   135      36.248  39.082  55.553  1.00 37.10
ATOM   1160  CB  LYS   135      38.472  37.187  56.805  1.00 39.10
ATOM   1161  CG  LYS   135      39.743  36.935  57.610  1.00 41.62
ATOM   1162  CD  LYS   135      40.827  35.990  56.972  1.00 43.08
ATOM   1163  CE  LYS   135      40.524  34.480  56.706  1.00 44.18
ATOM   1164  NZ  LYS   135      39.812  34.232  55.447  1.00 44.54
ATOM   1165  N   TYR   136      35.574  37.033  56.305  1.00 36.68
ATOM   1166  CA  TYR   136      34.445  36.820  55.406  1.00 35.62
ATOM   1167  C   TYR   136      33.478  37.987  55.474  1.00 34.94
ATOM   1168  O   TYR   136      33.189  38.622  54.468  1.00 34.43
ATOM   1169  CB  TYR   136      33.738  35.497  55.798  1.00 35.56
ATOM   1170  CG  TYR   136      32.379  35.231  55.128  1.00 35.74
ATOM   1171  CD1 TYR   136      31.281  34.902  55.912  1.00 35.19
ATOM   1172  CE1 TYR   136      30.059  34.699  55.298  1.00 36.00
ATOM   1173  CD2 TYR   136      32.230  35.346  53.735  1.00 35.63
ATOM   1174  CE2 TYR   136      31.003  35.145  53.128  1.00 34.96
ATOM   1175  CZ  TYR   136      29.919  34.820  53.907  1.00 35.46
ATOM   1176  OH  TYR   136      28.705  34.582  53.289  1.00 34.89
ATOM   1177  N   ILE   137      33.013  38.314  56.665  1.00 35.04
ATOM   1178  CA  ILE   137      32.087  39.393  56.864  1.00 35.77
ATOM   1179  C   ILE   137      32.696  40.715  56.417  1.00 38.28
ATOM   1180  O   ILE   137      31.947  41.588  55.951  1.00 40.12
ATOM   1181  CB  ILE   137      31.703  39.382  58.348  1.00 34.16
ATOM   1182  CG2 ILE   137      30.820  40.563  58.676  1.00 34.45
ATOM   1183  CG1 ILE   137      30.943  38.124  58.665  1.00 33.26
ATOM   1184  CD1 ILE   137      29.765  37.783  57.726  1.00 32.16
ATOM   1185  N   GLU   138      34.027  40.905  56.512  1.00 39.97
ATOM   1186  CA  GLU   138      34.698  42.116  56.015  1.00 40.18
ATOM   1187  C   GLU   138      34.644  42.174  54.484  1.00 38.85
ATOM   1188  O   GLU   138      34.351  43.203  53.874  1.00 38.14
ATOM   1189  CB  GLU   138      36.168  42.154  56.465  1.00 41.97
ATOM   1190  CG  GLU   138      36.352  42.198  57.960  1.00 44.78
ATOM   1191  CD  GLU   138      37.698  42.735  58.466  1.00 47.25
ATOM   1192  OE1 GLU   138      38.714  42.632  57.766  1.00 48.08
ATOM   1193  OE2 GLU   138      37.735  43.257  59.593  1.00 48.26
ATOM   1194  N   LYS   139      34.865  41.045  53.829  1.00 38.51
ATOM   1195  CA  LYS   139      34.807  40.950  52.390  1.00 38.27
ATOM   1196  C   LYS   139      33.399  41.260  51.906  1.00 38.27
ATOM   1197  O   LYS   139      33.257  42.084  51.015  1.00 37.65
ATOM   1198  CB  LYS   139      35.220  39.554  52.017  1.00 39.42
ATOM   1199  CG  LYS   139      35.707  39.453  50.596  1.00 41.29
ATOM   1200  CD  LYS   139      36.948  40.318  50.328  1.00 42.62
ATOM   1201  CE  LYS   139      36.766  41.379  49.217  1.00 43.99
ATOM   1202  NZ  LYS   139      35.629  42.252  49.505  1.00 44.78
ATOM   1203  N   VAL   140      32.389  40.696  52.595  1.00 38.27
ATOM   1204  CA  VAL   140      30.959  40.770  52.274  1.00 38.76
ATOM   1205  C   VAL   140      30.301  42.082  52.651  1.00 40.05
ATOM   1206  O   VAL   140      29.135  42.341  52.324  1.00 39.73
ATOM   1207  CB  VAL   140      30.245  39.508  52.958  1.00 38.21
ATOM   1208  CG1 VAL   140      29.094  39.822  53.895  1.00 37.06
ATOM   1209  CG2 VAL   140      29.709  38.654  51.830  1.00 37.46
ATOM   1210  N   ALA   141      31.020  42.945  53.348  1.00 42.04
ATOM   1211  CA  ALA   141      30.478  44.266  53.603  1.00 44.46
ATOM   1212  C   ALA   141      30.610  44.966  52.230  1.00 46.23
ATOM   1213  O   ALA   141      29.746  45.772  51.814  1.00 46.68
ATOM   1214  CB  ALA   141      31.318  44.979  54.677  1.00 43.99
ATOM   1215  N   GLU   142      31.719  44.666  51.505  1.00 47.48
ATOM   1216  CA  GLU   142      31.872  45.061  50.097  1.00 49.08
ATOM   1217  C   GLU   142      31.055  43.972  49.384  1.00 48.70
ATOM   1218  O   GLU   142      30.665  43.051  50.085  1.00 50.73
ATOM   1219  CB  GLU   142      33.308  44.964  49.703  1.00 50.87
ATOM   1220  CG  GLU   142      34.274  45.662  50.651  1.00 52.89
ATOM   1221  CD  GLU   142      35.698  45.161  50.405  1.00 54.84
ATOM   1222  OE1 GLU   142      36.264  45.435  49.336  1.00 55.90
ATOM   1223  OE2 GLU   142      36.244  44.463  51.270  1.00 55.82
ATOM   1224  N   LEU   143      30.699  43.797  48.111  1.00 47.43
ATOM   1225  CA  LEU   143      29.735  42.737  47.625  1.00 44.97
ATOM   1226  C   LEU   143      28.312  43.052  48.045  1.00 43.30
ATOM   1227  O   LEU   143      27.489  43.209  47.166  1.00 43.75
ATOM   1228  CB  LEU   143      29.935  41.256  48.126  1.00 43.51
ATOM   1229  CG  LEU   143      29.019  40.190  47.566  1.00 42.68
ATOM   1230  CD1 LEU   143      29.163  40.232  46.067  1.00 42.38
ATOM   1231  CD2 LEU   143      29.394  38.812  48.029  1.00 41.86
ATOM   1232  N   LEU   144      27.926  43.230  49.283  1.00 41.96
ATOM   1233  CA  LEU   144      26.559  43.543  49.573  1.00 41.67
ATOM   1234  C   LEU   144      26.242  45.010  49.512  1.00 42.30
ATOM   1235  O   LEU   144      25.138  45.365  49.916  1.00 41.43
ATOM   1236  CB  LEU   144      26.216  42.987  50.935  1.00 40.87
ATOM   1237  CG  LEU   144      25.504  41.646  50.967  1.00 41.06
ATOM   1238  CD1 LEU   144      25.815  40.742  49.789  1.00 40.89
ATOM   1239  CD2 LEU   144      25.986  40.951  52.201  1.00 41.89
ATOM   1240  N   GLU   145      27.032  45.871  48.867  1.00 43.78
ATOM   1241  CA  GLU   145      26.813  47.313  49.014  1.00 46.14
ATOM   1242  C   GLU   145      25.526  47.986  48.521  1.00 46.26
ATOM   1243  O   GLU   145      25.392  49.214  48.522  1.00 46.39
ATOM   1244  CB  GLU   145      28.006  48.048  48.405  1.00 47.65
ATOM   1245  CG  GLU   145      28.225  47.980  46.908  1.00 50.32
ATOM   1246  CD  GLU   145      28.408  49.342  46.209  1.00 52.25
ATOM   1247  OE1 GLU   145      28.895  49.314  45.060  1.00 53.14
ATOM   1248  OE2 GLU   145      28.065  50.403  46.786  1.00 52.50
ATOM   1249  N   LYS   146      24.561  47.187  48.081  1.00 46.74
ATOM   1250  CA  LYS   146      23.275  47.681  47.652  1.00 46.39
ATOM   1251  C   LYS   146      22.056  46.974  48.256  1.00 45.20
ATOM   1252  O   LYS   146      20.892  47.406  48.177  1.00 44.94
ATOM   1253  CB  LYS   146      23.250  47.607  46.140  1.00 48.28
ATOM   1254  CG  LYS   146      23.463  48.990  45.507  1.00 50.55
ATOM   1255  CD  LYS   146      22.637  50.158  46.157  1.00 52.38
ATOM   1256  CE  LYS   146      21.099  49.951  46.361  1.00 53.40
ATOM   1257  NZ  LYS   146      20.700  50.077  47.775  1.00 54.03
ATOM   1258  N   VAL   147      22.310  45.830  48.882  1.00 43.34
ATOM   1259  CA  VAL   147      21.250  45.099  49.556  1.00 41.30
ATOM   1260  C   VAL   147      20.945  45.865  50.854  1.00 40.45
ATOM   1261  O   VAL   147      21.824  46.577  51.353  1.00 40.63
ATOM   1262  CB  VAL   147      21.797  43.683  49.787  1.00 40.34
ATOM   1263  CG1 VAL   147      21.055  42.951  50.866  1.00 40.69
ATOM   1264  CG2 VAL   147      21.612  42.902  48.519  1.00 40.14
ATOM   1265  N   LYS   148      19.742  45.833  51.425  1.00 39.61
ATOM   1266  CA  LYS   148      19.586  46.433  52.747  1.00 38.29
ATOM   1267  C   LYS   148      19.273  45.420  53.822  1.00 36.33
ATOM   1268  O   LYS   148      19.501  45.720  54.993  1.00 36.72
ATOM   1269  CB  LYS   148      18.478  47.473  52.777  1.00 39.95
ATOM   1270  CG  LYS   148      19.054  48.845  53.162  1.00 42.70
ATOM   1271  CD  LYS   148      20.061  49.344  52.104  1.00 44.96
ATOM   1272  CE  LYS   148      20.883  50.580  52.478  1.00 46.13
ATOM   1273  NZ  LYS   148      21.477  51.138  51.257  1.00 47.98
ATOM   1274  N   LEU   149      18.815  44.204  53.479  1.00 33.78
ATOM   1275  CA  LEU   149      18.360  43.237  54.468  1.00 30.51
ATOM   1276  C   LEU   149      19.278  42.059  54.413  1.00 28.46
ATOM   1277  O   LEU   149      19.358  41.363  53.412  1.00 27.15
ATOM   1278  CB  LEU   149      16.958  42.745  54.185  1.00 29.87
ATOM   1279  CG  LEU   149      15.911  43.790  54.254  1.00 29.70
ATOM   1280  CD1 LEU   149      14.756  43.197  53.505  1.00 30.78
ATOM   1281  CD2 LEU   149      15.566  44.214  55.686  1.00 29.76
ATOM   1282  N   VAL   150      19.960  41.822  55.525  1.00 27.28
ATOM   1283  CA  VAL   150      20.969  40.789  55.602  1.00 24.53
ATOM   1284  C   VAL   150      20.610  39.917  56.819  1.00 22.63
ATOM   1285  O   VAL   150      20.132  40.412  57.831  1.00 22.64
ATOM   1286  CB  VAL   150      22.319  41.585  55.663  1.00 23.96
ATOM   1287  CG1 VAL   150      23.424  40.606  55.865  1.00 23.30
ATOM   1288  CG2 VAL   150      22.603  42.345  54.354  1.00 22.51
ATOM   1289  N   ALA   151      20.710  38.605  56.756  1.00 19.84
ATOM   1290  CA  ALA   151      20.430  37.748  57.858  1.00 18.11
ATOM   1291  C   ALA   151      21.751  36.999  58.058  1.00 18.34
ATOM   1292  O   ALA   151      22.373  36.566  57.087  1.00 18.50
ATOM   1293  CB  ALA   151      19.327  36.784  57.494  1.00 17.07
ATOM   1294  N   THR   152      22.214  36.797  59.289  1.00 18.29
ATOM   1295  CA  THR   152      23.496  36.191  59.553  1.00 19.88
ATOM   1296  C   THR   152      23.447  34.678  59.450  1.00 20.16
ATOM   1297  O   THR   152      24.108  34.052  58.608  1.00 21.38
ATOM   1298  CB  THR   152      24.036  36.602  60.979  1.00 20.55
ATOM   1299  OG1 THR   152      23.019  36.284  61.919  1.00 21.82
ATOM   1300  CG2 THR   152      24.336  38.095  61.146  1.00 20.03
ATOM   1301  N   PHE   153      22.718  34.030  60.332  1.00 19.74
ATOM   1302  CA  PHE   153      22.632  32.600  60.246  1.00 19.76
ATOM   1303  C   PHE   153      21.197  32.253  59.913  1.00 20.41
ATOM   1304  O   PHE   153      20.233  32.887  60.390  1.00 20.36
ATOM   1305  CB  PHE   153      23.011  31.914  61.583  1.00 18.96
ATOM   1306  CG  PHE   153      24.479  32.049  61.897  1.00 17.95
ATOM   1307  CD1 PHE   153      25.369  31.143  61.341  1.00 17.83
ATOM   1308  CD2 PHE   153      24.924  33.167  62.608  1.00 17.64
ATOM   1309  CE1 PHE   153      26.736  31.378  61.472  1.00 18.94
ATOM   1310  CE2 PHE   153      26.296  33.398  62.731  1.00 18.55
ATOM   1311  CZ  PHE   153      27.200  32.510  62.160  1.00 18.43
ATOM   1312  N   ASN   154      21.144  31.232  59.062  1.00 21.38
ATOM   1313  CA  ASN   154      19.926  30.537  58.756  1.00 22.40
ATOM   1314  C   ASN   154      19.819  29.346  59.687  1.00 24.43
ATOM   1315  O   ASN   154      20.602  28.394  59.658  1.00 25.07
ATOM   1316  CB  ASN   154      19.891  29.998  57.362  1.00 21.73
ATOM   1317  CG  ASN   154      18.571  29.287  57.078  1.00 21.66
ATOM   1318  OD1 ASN   154      18.561  28.087  56.847  1.00 21.55
ATOM   1319  ND2 ASN   154      17.417  29.919  57.036  1.00 20.47
ATOM   1320  N   GLU   155      18.871  29.498  60.597  1.00 25.66
ATOM   1321  CA  GLU   155      18.503  28.448  61.535  1.00 27.19
ATOM   1322  C   GLU   155      19.675  27.829  62.310  1.00 26.30
ATOM   1323  O   GLU   155      20.007  26.632  62.159  1.00 25.32
ATOM   1324  CB  GLU   155      17.745  27.349  60.771  1.00 28.65
ATOM   1325  CG  GLU   155      16.442  27.642  60.051  1.00 29.73
ATOM   1326  CD  GLU   155      15.843  26.415  59.403  1.00 30.82
ATOM   1327  OE1 GLU   155      14.666  26.433  59.047  1.00 31.93
ATOM   1328  OE2 GLU   155      16.552  25.428  59.247  1.00 31.36
ATOM   1329  N   PRO   156      20.291  28.649  63.202  1.00 25.82
ATOM   1330  CA  PRO   156      21.515  28.289  63.938  1.00 25.18
ATOM   1331  C   PRO   156      21.244  27.064  64.778  1.00 24.80
ATOM   1332  O   PRO   156      21.980  26.071  64.685  1.00 24.60
ATOM   1333  CB  PRO   156      21.853  29.542  64.697  1.00 24.37
ATOM   1334  CG  PRO   156      20.537  30.282  64.748  1.00 24.51
ATOM   1335  CD  PRO   156      19.959  30.058  63.419  1.00 24.76
ATOM   1336  N   MET   157      20.122  27.035  65.503  1.00 24.98
ATOM   1337  CA  MET   157      19.761  25.837  66.246  1.00 24.82
ATOM   1338  C   MET   157      19.415  24.604  65.433  1.00 24.66
ATOM   1339  O   MET   157      19.502  23.524  65.990  1.00 26.22
ATOM   1340  CB  MET   157      18.629  26.158  67.156  1.00 26.16
ATOM   1341  CG  MET   157      19.197  26.940  68.350  1.00 26.90
ATOM   1342  SD  MET   157      19.846  25.828  69.626  1.00 27.69
ATOM   1343  CE  MET   157      19.073  26.824  70.858  1.00 27.07
ATOM   1344  N   VAL   158      19.091  24.610  64.135  1.00 24.11
ATOM   1345  CA  VAL   158      18.838  23.379  63.381  1.00 21.82
ATOM   1346  C   VAL   158      20.243  22.969  62.957  1.00 22.11
ATOM   1347  O   VAL   158      20.507  21.783  62.790  1.00 22.08
ATOM   1348  CB  VAL   158      17.865  23.655  62.112  1.00 21.15
ATOM   1349  CG1 VAL   158      17.796  22.490  61.132  1.00 19.56
ATOM   1350  CG2 VAL   158      16.434  23.867  62.597  1.00 19.22
ATOM   1351  N   TYR   159      21.189  23.891  62.748  1.00 22.74
ATOM   1352  CA  TYR   159      22.571  23.573  62.458  1.00 22.48
ATOM   1353  C   TYR   159      23.219  22.858  63.638  1.00 22.57
ATOM   1354  O   TYR   159      23.899  21.835  63.490  1.00 22.20
ATOM   1355  CB  TYR   159      23.317  24.833  62.179  1.00 23.01
ATOM   1356  CG  TYR   159      24.753  24.572  61.745  1.00 24.58
ATOM   1357  CD1 TYR   159      25.011  23.702  60.685  1.00 25.51
ATOM   1358  CE1 TYR   159      26.307  23.503  60.236  1.00 25.50
ATOM   1359  CD2 TYR   159      25.817  25.230  62.348  1.00 24.82
ATOM   1360  CE2 TYR   159      27.116  25.043  61.894  1.00 24.94
ATOM   1361  CZ  TYR   159      27.330  24.186  60.848  1.00 24.95
ATOM   1362  OH  TYR   159      28.579  24.062  60.349  1.00 26.41
ATOM   1363  N   VAL   160      22.988  23.381  64.835  1.00 23.13
ATOM   1364  CA  VAL   160      23.512  22.793  66.076  1.00 23.94
ATOM   1365  C   VAL   160      22.900  21.436  66.266  1.00 24.64
ATOM   1366  O   VAL   160      23.603  20.440  66.407  1.00 24.54
ATOM   1367  CB  VAL   160      23.180  23.714  67.294  1.00 23.82
ATOM   1368  CG1 VAL   160      23.320  22.952  68.593  1.00 23.72
ATOM   1369  CG2 VAL   160      24.112  24.931  67.286  1.00 22.50
ATOM   1370  N   MET   161      21.572  21.400  66.266  1.00 27.22
ATOM   1371  CA  MET   161      20.840  20.155  66.398  1.00 29.08
ATOM   1372  C   MET   161      21.264  19.054  65.422  1.00 29.14
ATOM   1373  O   MET   161      21.588  17.924  65.779  1.00 29.28
ATOM   1374  CB  MET   161      19.376  20.420  66.203  1.00 30.41
ATOM   1375  CG  MET   161      18.590  19.270  66.779  1.00 31.86
ATOM   1376  SD  MET   161      16.966  19.126  66.022  1.00 33.21
ATOM   1377  CE  MET   161      16.223  18.326  67.418  1.00 31.02
ATOM   1378  N   MET   162      21.358  19.374  64.154  1.00 30.05
ATOM   1379  CA  MET   162      21.674  18.401  63.126  1.00 29.78
ATOM   1380  C   MET   162      23.093  17.890  63.116  1.00 29.19
ATOM   1381  O   MET   162      23.273  16.670  63.249  1.00 29.91
ATOM   1382  CB  MET   162      21.306  19.005  61.729  1.00 29.54
ATOM   1383  CG  MET   162      19.793  19.087  61.413  1.00 28.11
ATOM   1384  SD  MET   162      18.973  17.479  61.414  1.00 27.13
ATOM   1385  CE  MET   162      18.142  17.520  62.961  1.00 26.63
ATOM   1386  N   GLY   163      24.081  18.755  62.969  1.00 28.64
ATOM   1387  CA  GLY   163      25.447  18.284  62.930  1.00 29.44
ATOM   1388  C   GLY   163      26.112  17.999  64.282  1.00 29.49
ATOM   1389  O   GLY   163      27.185  17.389  64.253  1.00 29.32
ATOM   1390  N   TYR   164      25.567  18.382  65.443  1.00 29.51
ATOM   1391  CA  TYR   164      26.268  18.238  66.716  1.00 30.11
ATOM   1392  C   TYR   164      25.548  17.463  67.751  1.00 30.79
ATOM   1393  O   TYR   164      26.171  16.832  68.591  1.00 31.29
ATOM   1394  CB  TYR   164      26.596  19.593  67.347  1.00 29.76
ATOM   1395  CG  TYR   164      27.666  20.304  66.529  1.00 30.39
ATOM   1396  CD1 TYR   164      28.999  20.027  66.837  1.00 30.58
ATOM   1397  CE1 TYR   164      29.994  20.565  66.024  1.00 30.72
ATOM   1398  CD2 TYR   164      27.339  21.128  65.429  1.00 29.20
ATOM   1399  CE2 TYR   164      28.337  21.664  64.630  1.00 28.60
ATOM   1400  CZ  TYR   164      29.655  21.370  64.940  1.00 29.71
ATOM   1401  OH  TYR   164      30.684  21.862  64.180  1.00 30.29
ATOM   1402  N   LEU   165      24.237  17.494  67.717  1.00 32.28
ATOM   1403  CA  LEU   165      23.435  16.806  68.712  1.00 32.53
ATOM   1404  C   LEU   165      22.752  15.527  68.194  1.00 32.91
ATOM   1405  O   LEU   165      22.566  14.499  68.857  1.00 33.47
ATOM   1406  CB  LEU   165      22.486  17.876  69.169  1.00 32.32
ATOM   1407  CG  LEU   165      21.526  17.671  70.277  1.00 32.96
ATOM   1408  CD1 LEU   165      22.070  16.778  71.401  1.00 33.79
ATOM   1409  CD2 LEU   165      21.229  19.067  70.771  1.00 33.37
ATOM   1410  N   THR   166      22.334  15.554  66.964  1.00 33.19
ATOM   1411  CA  THR   166      21.637  14.433  66.423  1.00 33.01
ATOM   1412  C   THR   166      22.578  13.663  65.530  1.00 34.05
ATOM   1413  O   THR   166      22.315  12.489  65.280  1.00 34.99
ATOM   1414  CB  THR   166      20.428  15.127  65.803  1.00 32.29
ATOM   1415  OG1 THR   166      19.374  14.875  66.720  1.00 31.21
ATOM   1416  CG2 THR   166      20.156  14.753  64.403  1.00 32.10
ATOM   1417  N   ALA   167      23.677  14.252  65.062  1.00 34.07
ATOM   1418  CA  ALA   167      24.624  13.586  64.195  1.00 35.34
ATOM   1419  C   ALA   167      24.044  13.241  62.831  1.00 36.74
ATOM   1420  O   ALA   167      24.501  12.328  62.133  1.00 37.23
ATOM   1421  CB  ALA   167      25.149  12.292  64.844  1.00 34.69
ATOM   1422  N   TYR   168      23.053  14.016  62.382  1.00 37.39
ATOM   1423  CA  TYR   168      22.442  13.740  61.097  1.00 37.55
ATOM   1424  C   TYR   168      23.215  14.466  59.999  1.00 37.14
ATOM   1425  O   TYR   168      23.354  13.917  58.923  1.00 36.67
ATOM   1426  CB  TYR   168      21.028  14.209  61.196  1.00 39.51
ATOM   1427  CG  TYR   168      20.053  13.774  60.111  1.00 41.61
ATOM   1428  CD1 TYR   168      19.451  12.507  60.202  1.00 41.94
ATOM   1429  CE1 TYR   168      18.501  12.126  59.248  1.00 42.83
ATOM   1430  CD2 TYR   168      19.717  14.667  59.071  1.00 41.59
ATOM   1431  CE2 TYR   168      18.767  14.299  58.123  1.00 42.55
ATOM   1432  CZ  TYR   168      18.169  13.025  58.221  1.00 43.28
ATOM   1433  OH  TYR   168      17.241  12.644  57.271  1.00 43.80
ATOM   1434  N   TRP   169      23.742  15.686  60.177  1.00 36.39
ATOM   1435  CA  TRP   169      24.450  16.375  59.103  1.00 35.37
ATOM   1436  C   TRP   169      25.920  16.522  59.439  1.00 34.92
ATOM   1437  O   TRP   169      26.267  16.213  60.594  1.00 35.49
ATOM   1438  CB  TRP   169      23.883  17.742  58.904  1.00 35.62
ATOM   1439  CG  TRP   169      22.489  17.819  58.320  1.00 36.02
ATOM   1440  CD2 TRP   169      21.727  18.952  58.297  1.00 36.21
ATOM   1441  CE2 TRP   169      20.540  18.483  57.727  1.00 36.36
ATOM   1442  CE3 TRP   169      21.854  20.283  58.684  1.00 36.26
ATOM   1443  CD1 TRP   169      21.841  16.739  57.793  1.00 36.33
ATOM   1444  NE1 TRP   169      20.657  17.172  57.453  1.00 36.34
ATOM   1445  CZ2 TRP   169      19.462  19.351  57.538  1.00 36.14
ATOM   1446  CZ3 TRP   169      20.765  21.135  58.494  1.00 36.66
ATOM   1447  CH2 TRP   169      19.574  20.682  57.925  1.00 35.83
ATOM   1448  N   PRO   170      26.840  16.966  58.545  1.00 34.34
ATOM   1449  CA  PRO   170      28.198  17.383  58.901  1.00 33.94
ATOM   1450  C   PRO   170      28.289  18.239  60.177  1.00 34.00
ATOM   1451  O   PRO   170      27.523  19.189  60.283  1.00 34.36
ATOM   1452  CB  PRO   170      28.660  18.070  57.620  1.00 34.01
ATOM   1453  CG  PRO   170      28.065  17.226  56.512  1.00 33.56
ATOM   1454  CD  PRO   170      26.688  16.947  57.080  1.00 34.39
ATOM   1455  N   PRO   171      29.156  18.052  61.187  1.00 34.56
ATOM   1456  CA  PRO   171      30.313  17.164  61.138  1.00 34.79
ATOM   1457  C   PRO   171      30.109  15.769  61.730  1.00 35.05
ATOM   1458  O   PRO   171      31.076  15.029  61.929  1.00 35.30
ATOM   1459  CB  PRO   171      31.378  18.022  61.826  1.00 34.60
ATOM   1460  CG  PRO   171      30.604  18.620  62.978  1.00 34.03
ATOM   1461  CD  PRO   171      29.259  18.937  62.352  1.00 34.18
ATOM   1462  N   PHE   172      28.838  15.429  61.953  1.00 34.78
ATOM   1463  CA  PHE   172      28.395  14.160  62.468  1.00 35.06
ATOM   1464  C   PHE   172      28.730  13.841  63.923  1.00 35.20
ATOM   1465  O   PHE   172      29.104  12.729  64.304  1.00 35.91
ATOM   1466  CB  PHE   172      28.921  13.072  61.562  1.00 34.59
ATOM   1467  CG  PHE   172      28.334  13.207  60.184  1.00 35.09
ATOM   1468  CD1 PHE   172      29.142  13.640  59.130  1.00 35.68
ATOM   1469  CD2 PHE   172      26.994  12.897  59.977  1.00 35.07
ATOM   1470  CE1 PHE   172      28.591  13.759  57.859  1.00 35.94
ATOM   1471  CE2 PHE   172      26.466  13.025  58.704  1.00 34.68
ATOM   1472  CZ  PHE   172      27.252  13.450  57.649  1.00 34.83
ATOM   1473  N   ILE   173      28.454  14.800  64.803  1.00 34.70
ATOM   1474  CA  ILE   173      28.753  14.664  66.221  1.00 33.09
ATOM   1475  C   ILE   173      27.456  14.412  66.982  1.00 33.49
ATOM   1476  O   ILE   173      26.404  14.876  66.577  1.00 34.24
ATOM   1477  CB  ILE   173      29.521  15.975  66.612  1.00 31.04
ATOM   1478  CG2 ILE   173      29.694  16.148  68.113  1.00 30.34
ATOM   1479  CG1 ILE   173      30.843  15.914  65.860  1.00 29.32
ATOM   1480  CD1 ILE   173      31.845  17.028  66.127  1.00 29.27
ATOM   1481  N   ARG   174      27.493  13.707  68.108  1.00 34.94
ATOM   1482  CA  ARG   174      26.350  13.329  68.928  1.00 34.60
ATOM   1483  C   ARG   174      26.812  13.735  70.326  1.00 33.38
ATOM   1484  O   ARG   174      27.052  12.876  71.171  1.00 32.35
ATOM   1485  CB  ARG   174      26.242  11.856  68.731  1.00 36.93
ATOM   1486  CG  ARG   174      25.053  10.975  69.080  1.00 40.43
ATOM   1487  CD  ARG   174      25.527   9.465  69.143  1.00 43.07
ATOM   1488  NE  ARG   174      26.184   8.768  68.003  1.00 44.61
ATOM   1489  CZ  ARG   174      27.520   8.762  67.753  1.00 46.46
ATOM   1490  NH1 ARG   174      28.415   9.421  68.530  1.00 47.69
ATOM   1491  NH2 ARG   174      28.011   8.071  66.703  1.00 46.45
ATOM   1492  N   SER   175      27.026  15.016  70.608  1.00 32.52
ATOM   1493  CA  SER   175      27.573  15.464  71.881  1.00 32.94
ATOM   1494  C   SER   175      26.921  16.676  72.531  1.00 32.20
ATOM   1495  O   SER   175      27.066  17.810  72.071  1.00 32.50
ATOM   1496  CB  SER   175      29.088  15.762  71.726  1.00 33.96
ATOM   1497  OG  SER   175      29.736  16.237  72.921  1.00 34.86
ATOM   1498  N   PRO   176      26.257  16.541  73.661  1.00 31.98
ATOM   1499  CA  PRO   176      25.510  17.603  74.307  1.00 32.96
ATOM   1500  C   PRO   176      26.320  18.830  74.588  1.00 33.90
ATOM   1501  O   PRO   176      25.938  19.969  74.340  1.00 34.28
ATOM   1502  CB  PRO   176      24.993  17.019  75.574  1.00 33.09
ATOM   1503  CG  PRO   176      24.916  15.564  75.200  1.00 33.37
ATOM   1504  CD  PRO   176      26.177  15.312  74.421  1.00 32.36
ATOM   1505  N   PHE   177      27.526  18.522  75.025  1.00 35.35
ATOM   1506  CA  PHE   177      28.438  19.539  75.502  1.00 36.87
ATOM   1507  C   PHE   177      28.899  20.418  74.325  1.00 35.92
ATOM   1508  O   PHE   177      28.828  21.668  74.335  1.00 36.50
ATOM   1509  CB  PHE   177      29.635  18.825  76.217  1.00 39.53
ATOM   1510  CG  PHE   177      29.299  17.524  76.984  1.00 42.25
ATOM   1511  CD1 PHE   177      30.222  16.474  76.981  1.00 43.28
ATOM   1512  CD2 PHE   177      28.074  17.327  77.653  1.00 42.99
ATOM   1513  CE1 PHE   177      29.900  15.269  77.634  1.00 44.31
ATOM   1514  CE2 PHE   177      27.768  16.124  78.297  1.00 43.26
ATOM   1515  CZ  PHE   177      28.679  15.088  78.291  1.00 43.49
ATOM   1516  N   LYS   178      29.303  19.730  73.247  1.00 33.33
ATOM   1517  CA  LYS   178      29.797  20.425  72.078  1.00 30.73
ATOM   1518  C   LYS   178      28.679  21.202  71.398  1.00 29.09
ATOM   1519  O   LYS   178      28.942  22.332  70.981  1.00 28.34
ATOM   1520  CB  LYS   178      30.384  19.449  71.082  1.00 30.69
ATOM   1521  CG  LYS   178      31.496  18.640  71.642  1.00 30.97
ATOM   1522  CD  LYS   178      32.245  18.153  70.448  1.00 32.57
ATOM   1523  CE  LYS   178      33.270  17.100  70.847  1.00 33.72
ATOM   1524  NZ  LYS   178      33.777  16.407  69.664  1.00 34.81
ATOM   1525  N   ALA   179      27.436  20.663  71.353  1.00 26.76
ATOM   1526  CA  ALA   179      26.348  21.307  70.651  1.00 24.87
ATOM   1527  C   ALA   179      26.080  22.661  71.289  1.00 25.23
ATOM   1528  O   ALA   179      25.849  23.661  70.582  1.00 24.41
ATOM   1529  CB  ALA   179      25.130  20.430  70.708  1.00 23.17
ATOM   1530  N   PHE   180      26.256  22.771  72.622  1.00 25.70
ATOM   1531  CA  PHE   180      26.059  24.065  73.224  1.00 25.71
ATOM   1532  C   PHE   180      27.268  24.946  73.040  1.00 25.45
ATOM   1533  O   PHE   180      27.107  26.172  73.008  1.00 26.32
ATOM   1534  CB  PHE   180      25.714  23.889  74.663  1.00 26.84
ATOM   1535  CG  PHE   180      24.235  23.508  74.779  1.00 29.17
ATOM   1536  CD1 PHE   180      23.860  22.244  75.257  1.00 29.98
ATOM   1537  CD2 PHE   180      23.226  24.406  74.389  1.00 30.08
ATOM   1538  CE1 PHE   180      22.511  21.879  75.343  1.00 30.08
ATOM   1539  CE2 PHE   180      21.879  24.028  74.476  1.00 30.37
ATOM   1540  CZ  PHE   180      21.532  22.767  74.949  1.00 29.95
ATOM   1541  N   LYS   181      28.459  24.410  72.792  1.00 24.28
ATOM   1542  CA  LYS   181      29.565  25.301  72.621  1.00 25.09
ATOM   1543  C   LYS   181      29.411  25.924  71.264  1.00 24.27
ATOM   1544  O   LYS   181      29.642  27.136  71.155  1.00 26.31
ATOM   1545  CB  LYS   181      30.903  24.576  72.708  1.00 27.51
ATOM   1546  CG  LYS   181      32.124  25.438  73.079  1.00 29.47
ATOM   1547  CD  LYS   181      33.346  24.518  73.280  1.00 31.78
ATOM   1548  CE  LYS   181      33.049  23.534  74.440  1.00 33.31
ATOM   1549  NZ  LYS   181      33.472  22.143  74.184  1.00 34.47
ATOM   1550  N   VAL   182      28.983  25.176  70.239  1.00 22.42
ATOM   1551  CA  VAL   182      28.737  25.751  68.912  1.00 20.61
ATOM   1552  C   VAL   182      27.623  26.851  68.886  1.00 19.78
ATOM   1553  O   VAL   182      27.836  27.914  68.268  1.00 17.74
ATOM   1554  CB  VAL   182      28.392  24.629  67.983  1.00 19.86
ATOM   1555  CG1 VAL   182      28.405  25.136  66.592  1.00 20.16
ATOM   1556  CG2 VAL   182      29.461  23.596  67.977  1.00 20.18
ATOM   1557  N   ALA   183      26.476  26.674  69.597  1.00 18.00
ATOM   1558  CA  ALA   183      25.438  27.676  69.655  1.00 18.53
ATOM   1559  C   ALA   183      26.038  28.924  70.237  1.00 20.39
ATOM   1560  O   ALA   183      25.920  29.992  69.615  1.00 22.28
ATOM   1561  CB  ALA   183      24.267  27.319  70.549  1.00 16.75
ATOM   1562  N   ALA   184      26.798  28.837  71.349  1.00 21.69
ATOM   1563  CA  ALA   184      27.369  30.023  72.011  1.00 19.83
ATOM   1564  C   ALA   184      28.251  30.777  71.064  1.00 19.58
ATOM   1565  O   ALA   184      28.145  31.998  70.929  1.00 19.45
ATOM   1566  CB  ALA   184      28.164  29.582  73.180  1.00 20.45
ATOM   1567  N   ASN   185      29.018  30.003  70.321  1.00 19.99
ATOM   1568  CA  ASN   185      29.857  30.551  69.278  1.00 21.92
ATOM   1569  C   ASN   185      29.152  31.015  68.023  1.00 22.22
ATOM   1570  O   ASN   185      29.702  31.857  67.288  1.00 24.04
ATOM   1571  CB  ASN   185      30.919  29.569  68.828  1.00 24.11
ATOM   1572  CG  ASN   185      32.058  29.400  69.824  1.00 25.24
ATOM   1573  OD1 ASN   185      32.401  30.274  70.613  1.00 25.73
ATOM   1574  ND2 ASN   185      32.684  28.251  69.876  1.00 26.43
ATOM   1575  N   LEU   186      27.933  30.564  67.721  1.00 21.04
ATOM   1576  CA  LEU   186      27.178  31.123  66.613  1.00 19.34
ATOM   1577  C   LEU   186      26.629  32.474  67.077  1.00 18.64
ATOM   1578  O   LEU   186      26.572  33.464  66.337  1.00 17.71
ATOM   1579  CB  LEU   186      26.050  30.165  66.273  1.00 20.78
ATOM   1580  CG  LEU   186      26.337  28.811  65.670  1.00 20.11
ATOM   1581  CD1 LEU   186      25.063  28.055  65.618  1.00 19.98
ATOM   1582  CD2 LEU   186      26.981  28.958  64.316  1.00 20.66
ATOM   1583  N   LEU   187      26.202  32.547  68.346  1.00 18.14
ATOM   1584  CA  LEU   187      25.774  33.775  68.998  1.00 18.21
ATOM   1585  C   LEU   187      26.915  34.815  69.025  1.00 20.36
ATOM   1586  O   LEU   187      26.671  36.008  68.788  1.00 21.77
ATOM   1587  CB  LEU   187      25.330  33.411  70.393  1.00 16.45
ATOM   1588  CG  LEU   187      23.865  33.025  70.621  1.00 15.20
ATOM   1589  CD1 LEU   187      23.574  32.390  71.950  1.00 13.18
ATOM   1590  CD2 LEU   187      23.094  34.308  70.576  1.00 14.65
ATOM   1591  N   LYS   188      28.210  34.470  69.233  1.00 21.62
ATOM   1592  CA  LYS   188      29.325  35.427  69.196  1.00 20.76
ATOM   1593  C   LYS   188      29.536  35.799  67.744  1.00 19.83
ATOM   1594  O   LYS   188      29.705  36.982  67.459  1.00 19.98
ATOM   1595  CB  LYS   188      30.611  34.797  69.761  1.00 22.34
ATOM   1596  CG  LYS   188      30.497  34.142  71.177  1.00 23.99
ATOM   1597  CD  LYS   188      31.839  33.475  71.609  1.00 24.84
ATOM   1598  CE  LYS   188      31.749  32.723  72.954  1.00 24.46
ATOM   1599  NZ  LYS   188      32.566  31.519  72.972  1.00 23.11
ATOM   1600  N   ALA   189      29.524  34.849  66.784  1.00 18.89
ATOM   1601  CA  ALA   189      29.664  35.132  65.344  1.00 17.03
ATOM   1602  C   ALA   189      28.572  36.080  64.834  1.00 17.95
ATOM   1603  O   ALA   189      28.844  37.015  64.056  1.00 18.09
ATOM   1604  CB  ALA   189      29.588  33.842  64.625  1.00 17.14
ATOM   1605  N   HIS   190      27.312  35.898  65.306  1.00 17.17
ATOM   1606  CA  HIS   190      26.236  36.856  65.087  1.00 16.40
ATOM   1607  C   HIS   190      26.692  38.211  65.598  1.00 15.84
ATOM   1608  O   HIS   190      26.636  39.177  64.833  1.00 15.84
ATOM   1609  CB  HIS   190      24.836  36.522  65.833  1.00 16.31
ATOM   1610  CG  HIS   190      23.757  37.556  65.451  1.00 14.74
ATOM   1611  CD2 HIS   190      23.165  38.481  66.272  1.00 14.79
ATOM   1612  ND1 HIS   190      23.312  37.850  64.242  1.00 14.65
ATOM   1613  CE1 HIS   190      22.531  38.891  64.312  1.00 13.66
ATOM   1614  NE2 HIS   190      22.441  39.272  65.532  1.00 12.27
ATOM   1615  N   ALA   191      27.134  38.340  66.848  1.00 16.17
ATOM   1616  CA  ALA   191      27.566  39.632  67.365  1.00 16.27
ATOM   1617  C   ALA   191      28.758  40.227  66.591  1.00 16.57
ATOM   1618  O   ALA   191      28.823  41.449  66.384  1.00 16.35
ATOM   1619  CB  ALA   191      27.910  39.470  68.832  1.00 16.23
ATOM   1620  N   ILE   192      29.679  39.448  66.024  1.00 17.52
ATOM   1621  CA  ILE   192      30.780  40.000  65.240  1.00 18.59
ATOM   1622  C   ILE   192      30.205  40.651  64.003  1.00 20.42
ATOM   1623  O   ILE   192      30.419  41.843  63.742  1.00 20.77
ATOM   1624  CB  ILE   192      31.743  38.830  64.924  1.00 19.05
ATOM   1625  CG2 ILE   192      32.608  39.143  63.695  1.00 19.85
ATOM   1626  CG1 ILE   192      32.582  38.530  66.186  1.00 18.72
ATOM   1627  CD1 ILE   192      33.339  37.216  66.024  1.00 18.65
ATOM   1628  N   ALA   193      29.350  39.863  63.319  1.00 22.07
ATOM   1629  CA  ALA   193      28.629  40.293  62.109  1.00 22.59
ATOM   1630  C   ALA   193      27.792  41.539  62.364  1.00 22.93
ATOM   1631  O   ALA   193      27.928  42.519  61.636  1.00 21.35
ATOM   1632  CB  ALA   193      27.638  39.198  61.565  1.00 21.89
ATOM   1633  N   TYR   194      26.997  41.558  63.433  1.00 23.98
ATOM   1634  CA  TYR   194      26.139  42.690  63.685  1.00 26.39
ATOM   1635  C   TYR   194      26.978  43.934  63.950  1.00 28.00
ATOM   1636  O   TYR   194      26.654  45.020  63.475  1.00 28.49
ATOM   1637  CB  TYR   194      25.223  42.344  64.860  1.00 26.40
ATOM   1638  CG  TYR   194      24.197  43.429  65.097  1.00 27.74
ATOM   1639  CD1 TYR   194      24.477  44.472  65.993  1.00 28.45
ATOM   1640  CE1 TYR   194      23.581  45.530  66.165  1.00 28.30
ATOM   1641  CD2 TYR   194      22.989  43.449  64.377  1.00 28.31
ATOM   1642  CE2 TYR   194      22.087  44.509  64.555  1.00 27.90
ATOM   1643  CZ  TYR   194      22.401  45.527  65.440  1.00 28.05
ATOM   1644  OH  TYR   194      21.538  46.569  65.613  1.00 29.36
ATOM   1645  N   GLU   195      28.104  43.808  64.630  1.00 30.53
ATOM   1646  CA  GLU   195      28.966  44.932  64.909  1.00 32.22
ATOM   1647  C   GLU   195      29.522  45.464  63.606  1.00 31.51
ATOM   1648  O   GLU   195      29.557  46.666  63.350  1.00 31.32
ATOM   1649  CB  GLU   195      30.110  44.483  65.775  1.00 35.43
ATOM   1650  CG  GLU   195      30.936  45.634  66.368  1.00 39.07
ATOM   1651  CD  GLU   195      30.803  45.619  67.877  1.00 41.42
ATOM   1652  OE1 GLU   195      31.188  44.583  68.453  1.00 41.73
ATOM   1653  OE2 GLU   195      30.288  46.612  68.440  1.00 42.00
ATOM   1654  N   LEU   196      29.958  44.534  62.777  1.00 31.15
ATOM   1655  CA  LEU   196      30.593  44.870  61.527  1.00 30.89
ATOM   1656  C   LEU   196      29.596  45.345  60.462  1.00 31.44
ATOM   1657  O   LEU   196      29.906  46.190  59.611  1.00 31.75
ATOM   1658  CB  LEU   196      31.360  43.607  61.156  1.00 30.89
ATOM   1659  CG  LEU   196      32.888  43.554  60.905  1.00 31.24
ATOM   1660  CD1 LEU   196      33.699  44.129  62.014  1.00 30.79
ATOM   1661  CD2 LEU   196      33.289  42.096  60.793  1.00 31.13
ATOM   1662  N   LEU   197      28.336  44.906  60.479  1.00 31.54
ATOM   1663  CA  LEU   197      27.427  45.229  59.392  1.00 31.46
ATOM   1664  C   LEU   197      26.308  46.177  59.676  1.00 32.08
ATOM   1665  O   LEU   197      25.835  46.846  58.756  1.00 30.80
ATOM   1666  CB  LEU   197      26.830  43.947  58.823  1.00 30.38
ATOM   1667  CG  LEU   197      27.870  43.103  58.119  1.00 29.44
ATOM   1668  CD1 LEU   197      27.316  41.738  57.907  1.00 29.20
ATOM   1669  CD2 LEU   197      28.288  43.765  56.823  1.00 29.20
ATOM   1670  N   HIS   198      25.956  46.337  60.941  1.00 33.89
ATOM   1671  CA  HIS   198      24.809  47.126  61.269  1.00 36.76
ATOM   1672  C   HIS   198      24.843  48.574  60.890  1.00 39.10
ATOM   1673  O   HIS   198      23.815  49.226  61.076  1.00 41.19
ATOM   1674  CB  HIS   198      24.556  46.995  62.735  1.00 38.44
ATOM   1675  CG  HIS   198      23.376  47.777  63.255  1.00 39.72
ATOM   1676  CD2 HIS   198      23.422  48.644  64.308  1.00 40.40
ATOM   1677  ND1 HIS   198      22.160  47.800  62.723  1.00 41.05
ATOM   1678  CE1 HIS   198      21.470  48.661  63.431  1.00 41.50
ATOM   1679  NE2 HIS   198      22.238  49.164  64.380  1.00 41.34
ATOM   1680  N   GLY   199      25.898  49.191  60.379  1.00 41.41
ATOM   1681  CA  GLY   199      25.767  50.590  59.948  1.00 43.35
ATOM   1682  C   GLY   199      24.907  50.698  58.685  1.00 43.81
ATOM   1683  O   GLY   199      23.811  51.257  58.675  1.00 42.74
ATOM   1684  N   LYS   200      25.395  50.079  57.612  1.00 45.63
ATOM   1685  CA  LYS   200      24.698  50.179  56.333  1.00 47.25
ATOM   1686  C   LYS   200      23.563  49.147  56.141  1.00 46.23
ATOM   1687  O   LYS   200      22.737  49.224  55.208  1.00 47.14
ATOM   1688  CB  LYS   200      25.773  50.064  55.204  1.00 49.29
ATOM   1689  CG  LYS   200      25.191  50.644  53.883  1.00 52.28
ATOM   1690  CD  LYS   200      25.890  50.286  52.537  1.00 53.75
ATOM   1691  CE  LYS   200      24.894  50.436  51.355  1.00 55.03
ATOM   1692  NZ  LYS   200      23.859  49.391  51.340  1.00 55.10
ATOM   1693  N   PHE   201      23.485  48.163  57.039  1.00 44.11
ATOM   1694  CA  PHE   201      22.572  47.067  56.848  1.00 41.78
ATOM   1695  C   PHE   201      21.676  46.808  58.020  1.00 40.82
ATOM   1696  O   PHE   201      21.962  47.170  59.177  1.00 40.34
ATOM   1697  CB  PHE   201      23.315  45.811  56.594  1.00 41.56
ATOM   1698  CG  PHE   201      24.251  45.931  55.427  1.00 42.20
ATOM   1699  CD1 PHE   201      25.630  46.049  55.667  1.00 42.29
ATOM   1700  CD2 PHE   201      23.734  45.904  54.124  1.00 42.73
ATOM   1701  CE1 PHE   201      26.507  46.137  54.589  1.00 42.47
ATOM   1702  CE2 PHE   201      24.616  45.993  53.047  1.00 43.00
ATOM   1703  CZ  PHE   201      26.004  46.108  53.280  1.00 43.37
ATOM   1704  N   LYS   202      20.563  46.144  57.639  1.00 39.35
ATOM   1705  CA  LYS   202      19.586  45.628  58.585  1.00 36.70
ATOM   1706  C   LYS   202      20.017  44.172  58.714  1.00 33.59
ATOM   1707  O   LYS   202      19.966  43.385  57.759  1.00 32.70
ATOM   1708  CB  LYS   202      18.167  45.835  58.015  1.00 37.54
ATOM   1709  CG  LYS   202      17.992  47.333  58.235  1.00 40.11
ATOM   1710  CD  LYS   202      16.619  48.002  58.148  1.00 42.17
ATOM   1711  CE  LYS   202      16.014  47.930  56.737  1.00 43.97
ATOM   1712  NZ  LYS   202      14.701  48.569  56.647  1.00 44.82
ATOM   1713  N   VAL   203      20.660  43.940  59.877  1.00 29.55
ATOM   1714  CA  VAL   203      21.245  42.645  60.200  1.00 25.15
ATOM   1715  C   VAL   203      20.407  41.921  61.231  1.00 22.82
ATOM   1716  O   VAL   203      20.105  42.388  62.328  1.00 21.72
ATOM   1717  CB  VAL   203      22.716  42.810  60.706  1.00 24.61
ATOM   1718  CG1 VAL   203      23.443  41.506  60.493  1.00 23.81
ATOM   1719  CG2 VAL   203      23.518  43.793  59.886  1.00 23.11
ATOM   1720  N   GLY   204      19.951  40.757  60.808  1.00 20.52
ATOM   1721  CA  GLY   204      19.062  39.974  61.596  1.00 18.16
ATOM   1722  C   GLY   204      19.546  38.567  61.542  1.00 17.28
ATOM   1723  O   GLY   204      20.628  38.259  61.046  1.00 16.31
ATOM   1724  N   ILE   205      18.713  37.680  62.038  1.00 16.44
ATOM   1725  CA  ILE   205      19.033  36.286  62.120  1.00 14.52
ATOM   1726  C   ILE   205      17.714  35.635  61.698  1.00 15.49
ATOM   1727  O   ILE   205      16.652  36.296  61.823  1.00 14.97
ATOM   1728  CB  ILE   205      19.429  36.002  63.574  1.00 14.68
ATOM   1729  CG2 ILE   205      18.274  36.266  64.558  1.00 13.69
ATOM   1730  CG1 ILE   205      19.891  34.582  63.652  1.00 14.86
ATOM   1731  CD1 ILE   205      20.876  34.467  64.813  1.00 15.33
ATOM   1732  N   VAL   206      17.806  34.372  61.231  1.00 13.84
ATOM   1733  CA  VAL   206      16.680  33.621  60.760  1.00 13.05
ATOM   1734  C   VAL   206      16.521  32.438  61.670  1.00 13.18
ATOM   1735  O   VAL   206      17.412  31.594  61.690  1.00 11.00
ATOM   1736  CB  VAL   206      16.974  33.187  59.315  1.00 13.48
ATOM   1737  CG1 VAL   206      16.117  31.984  58.893  1.00 12.39
ATOM   1738  CG2 VAL   206      16.766  34.422  58.440  1.00 12.62
ATOM   1739  N   LYS   207      15.392  32.366  62.344  1.00 14.01
ATOM   1740  CA  LYS   207      15.132  31.294  63.206  1.00 16.37
ATOM   1741  C   LYS   207      13.995  30.380  62.779  1.00 17.92
ATOM   1742  O   LYS   207      12.901  30.854  62.489  1.00 20.17
ATOM   1743  CB  LYS   207      14.824  31.799  64.584  1.00 17.99
ATOM   1744  CG  LYS   207      15.644  30.782  65.417  1.00 20.25
ATOM   1745  CD  LYS   207      15.248  30.618  66.836  1.00 21.04
ATOM   1746  CE  LYS   207      15.754  29.235  67.269  1.00 23.19
ATOM   1747  NZ  LYS   207      15.088  28.141  66.562  1.00 24.25
ATOM   1748  N   ASN   208      14.194  29.065  62.795  1.00 17.73
ATOM   1749  CA  ASN   208      13.172  28.093  62.555  1.00 19.14
ATOM   1750  C   ASN   208      12.275  27.983  63.758  1.00 19.90
ATOM   1751  O   ASN   208      12.780  27.603  64.815  1.00 21.37
ATOM   1752  CB  ASN   208      13.821  26.782  62.295  1.00 21.22
ATOM   1753  CG  ASN   208      12.820  25.725  61.921  1.00 22.94
ATOM   1754  OD1 ASN   208      12.378  25.559  60.790  1.00 24.58
ATOM   1755  ND2 ASN   208      12.432  24.975  62.911  1.00 24.03
ATOM   1756  N   ILE   209      10.988  28.258  63.768  1.00 20.07
ATOM   1757  CA  ILE   209      10.237  28.161  65.021  1.00 20.58
ATOM   1758  C   ILE   209       9.154  27.090  64.861  1.00 21.74
ATOM   1759  O   ILE   209       8.089  27.363  64.308  1.00 23.28
ATOM   1760  CB  ILE   209       9.639  29.573  65.367  1.00 19.55
ATOM   1761  CG2 ILE   209       8.837  29.539  66.665  1.00 18.21
ATOM   1762  CG1 ILE   209      10.794  30.575  65.369  1.00 17.72
ATOM   1763  CD1 ILE   209      10.511  31.827  66.128  1.00 18.33
ATOM   1764  N   PRO   210       9.369  25.818  65.192  1.00 21.76
ATOM   1765  CA  PRO   210       8.297  24.833  65.198  1.00 21.62
ATOM   1766  C   PRO   210       7.221  25.159  66.211  1.00 21.84
ATOM   1767  O   PRO   210       7.439  25.982  67.090  1.00 22.69
ATOM   1768  CB  PRO   210       9.013  23.525  65.468  1.00 22.14
ATOM   1769  CG  PRO   210      10.332  23.913  66.183  1.00 22.63
ATOM   1770  CD  PRO   210      10.679  25.248  65.525  1.00 21.82
ATOM   1771  N   ILE   211       6.009  24.648  66.144  1.00 21.86
ATOM   1772  CA  ILE   211       5.112  24.841  67.254  1.00 22.16
ATOM   1773  C   ILE   211       5.352  23.545  68.017  1.00 23.59
ATOM   1774  O   ILE   211       5.421  22.450  67.437  1.00 24.33
ATOM   1775  CB  ILE   211       3.657  25.021  66.739  1.00 21.85
ATOM   1776  CG2 ILE   211       2.643  25.010  67.877  1.00 21.85
ATOM   1777  CG1 ILE   211       3.555  26.384  66.060  1.00 21.93
ATOM   1778  CD1 ILE   211       3.866  27.629  66.960  1.00 21.30
ATOM   1779  N   ILE   212       5.631  23.664  69.312  1.00 23.83
ATOM   1780  CA  ILE   212       5.940  22.519  70.143  1.00 22.82
ATOM   1781  C   ILE   212       4.782  22.331  71.078  1.00 22.45
ATOM   1782  O   ILE   212       4.432  23.261  71.793  1.00 22.58
ATOM   1783  CB  ILE   212       7.293  22.847  70.848  1.00 22.94
ATOM   1784  CG2 ILE   212       7.472  22.068  72.146  1.00 21.29
ATOM   1785  CG1 ILE   212       8.398  22.545  69.829  1.00 21.68
ATOM   1786  CD1 ILE   212       9.619  23.408  70.095  1.00 22.71
ATOM   1787  N   LEU   213       4.259  21.112  71.138  1.00 22.56
ATOM   1788  CA  LEU   213       3.018  20.788  71.828  1.00 22.59
ATOM   1789  C   LEU   213       3.269  19.689  72.839  1.00 22.86
ATOM   1790  O   LEU   213       3.967  18.759  72.425  1.00 22.94
ATOM   1791  CB  LEU   213       1.977  20.308  70.768  1.00 22.30
ATOM   1792  CG  LEU   213       1.848  21.320  69.627  1.00 21.90
ATOM   1793  CD1 LEU   213       1.239  20.720  68.419  1.00 22.76
ATOM   1794  CD2 LEU   213       1.101  22.480  70.157  1.00 20.49
ATOM   1795  N   PRO   214       2.733  19.679  74.100  1.00 22.77
ATOM   1796  CA  PRO   214       2.758  18.534  74.983  1.00 22.63
ATOM   1797  C   PRO   214       2.145  17.368  74.262  1.00 23.07
ATOM   1798  O   PRO   214       1.145  17.532  73.585  1.00 24.89
ATOM   1799  CB  PRO   214       1.968  18.912  76.193  1.00 21.58
ATOM   1800  CG  PRO   214       1.136  20.082  75.819  1.00 21.64
ATOM   1801  CD  PRO   214       1.917  20.746  74.704  1.00 22.21
ATOM   1802  N   ALA   215       2.685  16.174  74.336  1.00 23.23
ATOM   1803  CA  ALA   215       2.028  15.065  73.707  1.00 23.51
ATOM   1804  C   ALA   215       0.870  14.637  74.571  1.00 23.96
ATOM   1805  O   ALA   215       0.252  13.618  74.273  1.00 24.75
ATOM   1806  CB  ALA   215       2.987  13.895  73.539  1.00 23.79
ATOM   1807  N   SER   216       0.574  15.311  75.680  1.00 25.03
ATOM   1808  CA  SER   216      -0.553  14.985  76.519  1.00 26.28
ATOM   1809  C   SER   216      -0.822  16.179  77.399  1.00 28.23
ATOM   1810  O   SER   216      -0.116  17.172  77.386  1.00 30.15
ATOM   1811  CB  SER   216      -0.239  13.744  77.338  1.00 25.48
ATOM   1812  OG  SER   216      -0.251  13.967  78.745  1.00 25.01
ATOM   1813  N   ASP   217      -1.800  16.059  78.251  1.00 32.10
ATOM   1814  CA  ASP   217      -2.328  17.130  79.077  1.00 35.78
ATOM   1815  C   ASP   217      -1.775  17.158  80.485  1.00 37.12
ATOM   1816  O   ASP   217      -2.109  18.074  81.255  1.00 36.50
ATOM   1817  CB  ASP   217      -3.815  16.948  79.162  1.00 38.11
ATOM   1818  CG  ASP   217      -4.632  18.061  78.583  1.00 40.17
ATOM   1819  OD1 ASP   217      -4.300  18.568  77.506  1.00 42.44
ATOM   1820  OD2 ASP   217      -5.621  18.397  79.218  1.00 41.48
ATOM   1821  N   LYS   218      -1.029  16.068  80.797  1.00 38.31
ATOM   1822  CA  LYS   218      -0.423  15.840  82.097  1.00 38.74
ATOM   1823  C   LYS   218       0.596  16.927  82.327  1.00 39.12
ATOM   1824  O   LYS   218       1.375  17.186  81.392  1.00 39.91
ATOM   1825  CB  LYS   218       0.277  14.519  82.113  1.00 38.60
ATOM   1826  CG  LYS   218      -0.689  13.416  81.854  1.00 39.53
ATOM   1827  CD  LYS   218      -0.029  12.082  82.112  1.00 40.60
ATOM   1828  CE  LYS   218       1.137  11.849  81.156  1.00 41.65
ATOM   1829  NZ  LYS   218       0.712  11.396  79.843  1.00 42.07
ATOM   1830  N   GLU   219       0.715  17.527  83.523  1.00 39.92
ATOM   1831  CA  GLU   219       1.688  18.598  83.726  1.00 40.20
ATOM   1832  C   GLU   219       3.112  18.165  83.441  1.00 39.25
ATOM   1833  O   GLU   219       3.954  18.971  83.075  1.00 39.38
ATOM   1834  CB  GLU   219       1.598  19.161  85.140  1.00 41.00
ATOM   1835  CG  GLU   219       1.609  20.730  85.037  1.00 44.13
ATOM   1836  CD  GLU   219       0.311  21.523  84.630  1.00 45.92
ATOM   1837  OE1 GLU   219      -0.459  21.934  85.527  1.00 46.80
ATOM   1838  OE2 GLU   219       0.081  21.785  83.434  1.00 45.86
ATOM   1839  N   ARG   220       3.379  16.870  83.458  1.00 39.34
ATOM   1840  CA  ARG   220       4.664  16.274  83.119  1.00 39.44
ATOM   1841  C   ARG   220       5.056  16.589  81.667  1.00 38.47
ATOM   1842  O   ARG   220       6.182  17.005  81.358  1.00 37.79
ATOM   1843  CB  ARG   220       4.464  14.777  83.449  1.00 41.55
ATOM   1844  CG  ARG   220       5.503  13.795  82.907  1.00 44.64
ATOM   1845  CD  ARG   220       5.486  12.310  83.356  1.00 46.04
ATOM   1846  NE  ARG   220       4.285  11.516  83.102  1.00 48.37
ATOM   1847  CZ  ARG   220       3.491  11.103  84.128  1.00 49.85
ATOM   1848  NH1 ARG   220       3.775  11.423  85.400  1.00 50.44
ATOM   1849  NH2 ARG   220       2.437  10.294  83.922  1.00 49.71
ATOM   1850  N   ASP   221       4.084  16.457  80.751  1.00 38.03
ATOM   1851  CA  ASP   221       4.261  16.714  79.311  1.00 36.53
ATOM   1852  C   ASP   221       4.055  18.198  78.990  1.00 36.00
ATOM   1853  O   ASP   221       4.718  18.754  78.105  1.00 34.96
ATOM   1854  CB  ASP   221       3.273  15.849  78.489  1.00 34.99
ATOM   1855  CG  ASP   221       3.541  14.351  78.603  1.00 34.42
ATOM   1856  OD1 ASP   221       4.669  13.939  78.761  1.00 34.37
ATOM   1857  OD2 ASP   221       2.632  13.550  78.540  1.00 34.40
ATOM   1858  N   ARG   222       3.173  18.885  79.710  1.00 35.60
ATOM   1859  CA  ARG   222       3.049  20.320  79.518  1.00 36.62
ATOM   1860  C   ARG   222       4.402  20.951  79.875  1.00 36.18
ATOM   1861  O   ARG   222       4.989  21.638  79.035  1.00 37.27
ATOM   1862  CB  ARG   222       1.869  20.853  80.397  1.00 37.35
ATOM   1863  CG  ARG   222       0.549  20.213  79.953  1.00 38.80
ATOM   1864  CD  ARG   222      -0.692  20.568  80.741  1.00 40.15
ATOM   1865  NE  ARG   222      -1.427  21.725  80.240  1.00 43.00
ATOM   1866  CZ  ARG   222      -2.442  21.671  79.324  1.00 43.86
ATOM   1867  NH1 ARG   222      -2.834  20.506  78.790  1.00 44.32
ATOM   1868  NH2 ARG   222      -3.163  22.779  79.008  1.00 43.73
ATOM   1869  N   LYS   223       5.014  20.645  81.031  1.00 35.65
ATOM   1870  CA  LYS   223       6.312  21.177  81.398  1.00 34.02
ATOM   1871  C   LYS   223       7.424  20.747  80.463  1.00 31.06
ATOM   1872  O   LYS   223       8.258  21.570  80.098  1.00 30.14
ATOM   1873  CB  LYS   223       6.593  20.777  82.830  1.00 36.74
ATOM   1874  CG  LYS   223       6.725  22.102  83.608  1.00 40.37
ATOM   1875  CD  LYS   223       8.087  22.822  83.207  1.00 43.05
ATOM   1876  CE  LYS   223       8.132  24.250  82.574  1.00 43.51
ATOM   1877  NZ  LYS   223       9.307  24.423  81.716  1.00 43.48
ATOM   1878  N   ALA   224       7.395  19.514  80.003  1.00 28.51
ATOM   1879  CA  ALA   224       8.312  19.027  79.003  1.00 27.46
ATOM   1880  C   ALA   224       8.267  19.835  77.720  1.00 28.59
ATOM   1881  O   ALA   224       9.330  20.145  77.163  1.00 29.51
ATOM   1882  CB  ALA   224       8.001  17.617  78.614  1.00 26.42
ATOM   1883  N   ALA   225       7.074  20.239  77.225  1.00 28.81
ATOM   1884  CA  ALA   225       6.953  20.990  75.973  1.00 27.44
ATOM   1885  C   ALA   225       7.473  22.386  76.193  1.00 28.01
ATOM   1886  O   ALA   225       8.103  22.945  75.282  1.00 28.18
ATOM   1887  CB  ALA   225       5.527  21.097  75.504  1.00 25.99
ATOM   1888  N   GLU   226       7.326  22.934  77.412  1.00 28.76
ATOM   1889  CA  GLU   226       7.864  24.263  77.735  1.00 30.22
ATOM   1890  C   GLU   226       9.371  24.321  77.649  1.00 29.90
ATOM   1891  O   GLU   226       9.954  25.179  76.971  1.00 29.79
ATOM   1892  CB  GLU   226       7.496  24.696  79.109  1.00 32.57
ATOM   1893  CG  GLU   226       6.031  24.592  78.992  1.00 36.25
ATOM   1894  CD  GLU   226       5.282  25.030  80.199  1.00 38.90
ATOM   1895  OE1 GLU   226       4.904  24.184  81.041  1.00 40.34
ATOM   1896  OE2 GLU   226       5.066  26.244  80.240  1.00 40.71
ATOM   1897  N   LYS   227       9.968  23.297  78.261  1.00 30.09
ATOM   1898  CA  LYS   227      11.408  23.099  78.324  1.00 29.34
ATOM   1899  C   LYS   227      11.958  23.028  76.930  1.00 26.95
ATOM   1900  O   LYS   227      12.764  23.874  76.549  1.00 26.78
ATOM   1901  CB  LYS   227      11.671  21.821  79.079  1.00 32.26
ATOM   1902  CG  LYS   227      13.120  21.548  79.410  1.00 34.53
ATOM   1903  CD  LYS   227      13.051  20.167  80.021  1.00 36.68
ATOM   1904  CE  LYS   227      14.449  19.709  80.331  1.00 38.09
ATOM   1905  NZ  LYS   227      14.389  18.668  81.347  1.00 39.64
ATOM   1906  N   ALA   228      11.456  22.054  76.184  1.00 24.46
ATOM   1907  CA  ALA   228      11.743  21.861  74.773  1.00 22.16
ATOM   1908  C   ALA   228      11.598  23.168  74.015  1.00 21.90
ATOM   1909  O   ALA   228      12.491  23.556  73.240  1.00 21.67
ATOM   1910  CB  ALA   228      10.762  20.860  74.160  1.00 21.06
ATOM   1911  N   ASP   229      10.534  23.937  74.269  1.00 20.95
ATOM   1912  CA  ASP   229      10.367  25.113  73.451  1.00 20.42
ATOM   1913  C   ASP   229      11.329  26.224  73.830  1.00 20.69
ATOM   1914  O   ASP   229      11.861  26.960  72.965  1.00 21.66
ATOM   1915  CB  ASP   229       8.890  25.543  73.531  1.00 19.16
ATOM   1916  CG  ASP   229       8.515  26.685  72.576  1.00 17.54
ATOM   1917  OD1 ASP   229       9.086  26.870  71.494  1.00 16.47
ATOM   1918  OD2 ASP   229       7.642  27.432  72.964  1.00 17.68
ATOM   1919  N   ASN   230      11.633  26.337  75.121  1.00 21.31
ATOM   1920  CA  ASN   230      12.687  27.260  75.578  1.00 21.07
ATOM   1921  C   ASN   230      14.088  26.837  75.148  1.00 19.66
ATOM   1922  O   ASN   230      14.883  27.715  74.881  1.00 19.58
ATOM   1923  CB  ASN   230      12.782  27.352  77.031  1.00 21.39
ATOM   1924  CG  ASN   230      11.752  28.174  77.726  1.00 21.38
ATOM   1925  OD1 ASN   230      11.614  28.024  78.925  1.00 23.11
ATOM   1926  ND2 ASN   230      11.066  29.130  77.169  1.00 22.71
ATOM   1927  N   LEU   231      14.440  25.570  75.079  1.00 18.94
ATOM   1928  CA  LEU   231      15.716  25.082  74.599  1.00 19.89
ATOM   1929  C   LEU   231      15.880  25.311  73.128  1.00 19.97
ATOM   1930  O   LEU   231      16.898  25.869  72.718  1.00 22.16
ATOM   1931  CB  LEU   231      15.911  23.573  74.776  1.00 20.92
ATOM   1932  CG  LEU   231      17.105  23.019  75.557  1.00 21.87
ATOM   1933  CD1 LEU   231      16.989  23.391  77.021  1.00 20.55
ATOM   1934  CD2 LEU   231      17.137  21.495  75.402  1.00 22.49
ATOM   1935  N   PHE   232      14.923  24.906  72.294  1.00 19.04
ATOM   1936  CA  PHE   232      15.081  25.075  70.857  1.00 16.48
ATOM   1937  C   PHE   232      14.898  26.514  70.435  1.00 16.86
ATOM   1938  O   PHE   232      15.532  26.943  69.455  1.00 16.88
ATOM   1939  CB  PHE   232      14.073  24.213  70.108  1.00 13.33
ATOM   1940  CG  PHE   232      14.522  24.053  68.666  1.00 12.60
ATOM   1941  CD1 PHE   232      13.873  24.737  67.635  1.00 11.57
ATOM   1942  CD2 PHE   232      15.593  23.227  68.360  1.00 11.29
ATOM   1943  CE1 PHE   232      14.285  24.600  66.333  1.00 10.01
ATOM   1944  CE2 PHE   232      15.999  23.096  67.038  1.00 11.01
ATOM   1945  CZ  PHE   232      15.347  23.780  66.022  1.00 10.12
ATOM   1946  N   ASN   233      14.036  27.293  71.107  1.00 18.18
ATOM   1947  CA  ASN   233      13.735  28.579  70.510  1.00 19.12
ATOM   1948  C   ASN   233      14.063  29.796  71.258  1.00 19.02
ATOM   1949  O   ASN   233      14.791  30.645  70.768  1.00 20.44
ATOM   1950  CB  ASN   233      12.255  28.743  70.158  1.00 20.52
ATOM   1951  CG  ASN   233      11.686  27.828  69.093  1.00 20.40
ATOM   1952  OD1 ASN   233      10.631  27.248  69.278  1.00 20.39
ATOM   1953  ND2 ASN   233      12.321  27.603  67.963  1.00 21.25
ATOM   1954  N   TRP   234      13.558  29.927  72.453  1.00 20.72
ATOM   1955  CA  TRP   234      13.721  31.186  73.174  1.00 23.18
ATOM   1956  C   TRP   234      15.026  31.397  73.887  1.00 23.60
ATOM   1957  O   TRP   234      15.419  32.557  73.907  1.00 24.25
ATOM   1958  CB  TRP   234      12.516  31.377  74.154  1.00 24.40
ATOM   1959  CG  TRP   234      11.268  31.081  73.318  1.00 25.90
ATOM   1960  CD2 TRP   234      10.961  31.627  72.084  1.00 26.39
ATOM   1961  CE2 TRP   234       9.862  30.841  71.709  1.00 27.05
ATOM   1962  CE3 TRP   234      11.436  32.627  71.229  1.00 26.32
ATOM   1963  CD1 TRP   234      10.411  30.074  73.679  1.00 26.90
ATOM   1964  NE1 TRP   234       9.579  29.952  72.671  1.00 27.70
ATOM   1965  CZ2 TRP   234       9.225  31.031  70.485  1.00 26.97
ATOM   1966  CZ3 TRP   234      10.807  32.818  70.007  1.00 26.85
ATOM   1967  CH2 TRP   234       9.710  32.025  69.639  1.00 27.22
ATOM   1968  N   HIS   235      15.809  30.431  74.401  1.00 23.69
ATOM   1969  CA  HIS   235      17.109  30.771  75.031  1.00 23.03
ATOM   1970  C   HIS   235      18.142  31.209  74.009  1.00 23.46
ATOM   1971  O   HIS   235      18.943  32.105  74.311  1.00 25.15
ATOM   1972  CB  HIS   235      17.736  29.627  75.771  1.00 21.77
ATOM   1973  CG  HIS   235      16.977  29.209  76.986  1.00 20.89
ATOM   1974  CD2 HIS   235      16.038  29.956  77.645  1.00 21.32
ATOM   1975  ND1 HIS   235      17.063  28.024  77.582  1.00 22.06
ATOM   1976  CE1 HIS   235      16.207  28.003  78.572  1.00 22.03
ATOM   1977  NE2 HIS   235      15.587  29.179  78.606  1.00 22.11
ATOM   1978  N   PHE   236      18.150  30.669  72.777  1.00 22.67
ATOM   1979  CA  PHE   236      19.088  31.165  71.779  1.00 21.07
ATOM   1980  C   PHE   236      18.681  32.576  71.407  1.00 22.04
ATOM   1981  O   PHE   236      19.573  33.373  71.160  1.00 23.17
ATOM   1982  CB  PHE   236      19.076  30.266  70.535  1.00 19.68
ATOM   1983  CG  PHE   236      20.034  30.686  69.444  1.00 17.71
ATOM   1984  CD1 PHE   236      19.687  31.657  68.522  1.00 17.60
ATOM   1985  CD2 PHE   236      21.290  30.127  69.396  1.00 17.89
ATOM   1986  CE1 PHE   236      20.601  32.083  67.567  1.00 17.70
ATOM   1987  CE2 PHE   236      22.211  30.544  68.434  1.00 18.08
ATOM   1988  CZ  PHE   236      21.878  31.531  67.515  1.00 18.18
ATOM   1989  N   LEU   237      17.394  32.962  71.359  1.00 22.12
ATOM   1990  CA  LEU   237      17.070  34.290  70.912  1.00 20.67
ATOM   1991  C   LEU   237      17.126  35.308  72.029  1.00 20.68
ATOM   1992  O   LEU   237      17.558  36.447  71.822  1.00 20.54
ATOM   1993  CB  LEU   237      15.700  34.221  70.234  1.00 20.28
ATOM   1994  CG  LEU   237      15.565  33.661  68.821  1.00 19.18
ATOM   1995  CD1 LEU   237      14.103  33.613  68.544  1.00 19.34
ATOM   1996  CD2 LEU   237      16.242  34.496  67.768  1.00 17.61
ATOM   1997  N   ASP   238      16.664  34.942  73.217  1.00 21.59
ATOM   1998  CA  ASP   238      16.915  35.681  74.462  1.00 22.63
ATOM   1999  C   ASP   238      18.367  36.155  74.565  1.00 22.73
ATOM   2000  O   ASP   238      18.660  37.351  74.655  1.00 21.46
ATOM   2001  CB  ASP   238      16.670  34.801  75.667  1.00 23.08
ATOM   2002  CG  ASP   238      15.212  34.525  75.961  1.00 24.33
ATOM   2003  OD1 ASP   238      14.378  35.256  75.435  1.00 25.27
ATOM   2004  OD2 ASP   238      14.910  33.591  76.716  1.00 25.27
ATOM   2005  N   ALA   239      19.265  35.166  74.430  1.00 23.51
ATOM   2006  CA  ALA   239      20.688  35.383  74.500  1.00 24.40
ATOM   2007  C   ALA   239      21.171  36.420  73.532  1.00 24.59
ATOM   2008  O   ALA   239      22.159  37.024  73.879  1.00 27.11
ATOM   2009  CB  ALA   239      21.456  34.103  74.231  1.00 23.59
ATOM   2010  N   ILE   240      20.606  36.788  72.397  1.00 24.91
ATOM   2011  CA  ILE   240      21.203  37.840  71.566  1.00 24.24
ATOM   2012  C   ILE   240      21.129  39.127  72.347  1.00 25.48
ATOM   2013  O   ILE   240      22.053  39.933  72.324  1.00 28.04
ATOM   2014  CB  ILE   240      20.437  37.989  70.233  1.00 23.12
ATOM   2015  CG2 ILE   240      20.744  39.318  69.570  1.00 23.28
ATOM   2016  CG1 ILE   240      20.827  36.871  69.307  1.00 21.57
ATOM   2017  CD1 ILE   240      19.914  36.758  68.090  1.00 19.84
ATOM   2018  N   TRP   241      20.058  39.347  73.093  1.00 26.74
ATOM   2019  CA  TRP   241      19.900  40.606  73.792  1.00 27.24
ATOM   2020  C   TRP   241      20.460  40.555  75.180  1.00 27.79
ATOM   2021  O   TRP   241      20.856  41.622  75.638  1.00 28.09
ATOM   2022  CB  TRP   241      18.397  41.020  73.859  1.00 28.35
ATOM   2023  CG  TRP   241      17.851  41.457  72.482  1.00 28.34
ATOM   2024  CD2 TRP   241      17.326  40.628  71.516  1.00 28.22
ATOM   2025  CE2 TRP   241      17.260  41.502  70.422  1.00 28.40
ATOM   2026  CE3 TRP   241      16.937  39.300  71.389  1.00 27.58
ATOM   2027  CD1 TRP   241      18.043  42.741  72.035  1.00 27.93
ATOM   2028  NE1 TRP   241      17.685  42.722  70.788  1.00 28.40
ATOM   2029  CZ2 TRP   241      16.807  41.067  69.180  1.00 28.20
ATOM   2030  CZ3 TRP   241      16.483  38.861  70.147  1.00 28.36
ATOM   2031  CH2 TRP   241      16.419  39.730  69.049  1.00 28.40
ATOM   2032  N   SER   242      20.529  39.384  75.855  1.00 27.77
ATOM   2033  CA  SER   242      20.993  39.317  77.235  1.00 27.08
ATOM   2034  C   SER   242      22.462  38.965  77.404  1.00 29.17
ATOM   2035  O   SER   242      22.986  39.169  78.510  1.00 30.29
ATOM   2036  CB  SER   242      20.205  38.290  78.081  1.00 24.73
ATOM   2037  OG  SER   242      20.520  36.916  77.934  1.00 21.12
ATOM   2038  N   GLY   243      23.190  38.422  76.430  1.00 29.44
ATOM   2039  CA  GLY   243      24.559  38.066  76.701  1.00 30.07
ATOM   2040  C   GLY   243      24.667  36.747  77.434  1.00 31.43
ATOM   2041  O   GLY   243      25.744  36.180  77.399  1.00 32.25
ATOM   2042  N   LYS   244      23.668  36.169  78.113  1.00 32.56
ATOM   2043  CA  LYS   244      23.799  34.854  78.754  1.00 33.02
ATOM   2044  C   LYS   244      23.129  33.750  77.920  1.00 32.51
ATOM   2045  O   LYS   244      22.005  33.901  77.451  1.00 31.70
ATOM   2046  CB  LYS   244      23.120  34.743  80.115  1.00 33.80
ATOM   2047  CG  LYS   244      22.915  36.031  80.894  1.00 35.91
ATOM   2048  CD  LYS   244      24.169  36.564  81.572  1.00 37.72
ATOM   2049  CE  LYS   244      23.807  37.822  82.348  1.00 39.26
ATOM   2050  NZ  LYS   244      23.360  38.915  81.482  1.00 40.43
ATOM   2051  N   TYR   245      23.750  32.597  77.747  1.00 32.97
ATOM   2052  CA  TYR   245      23.170  31.475  77.063  1.00 34.18
ATOM   2053  C   TYR   245      23.518  30.231  77.878  1.00 35.82
ATOM   2054  O   TYR   245      24.690  30.087  78.194  1.00 35.92
ATOM   2055  CB  TYR   245      23.765  31.463  75.673  1.00 33.36
ATOM   2056  CG  TYR   245      23.256  30.290  74.882  1.00 32.90
ATOM   2057  CD1 TYR   245      21.939  30.292  74.435  1.00 33.31
ATOM   2058  CE1 TYR   245      21.437  29.175  73.779  1.00 32.94
ATOM   2059  CD2 TYR   245      24.087  29.193  74.672  1.00 32.98
ATOM   2060  CE2 TYR   245      23.597  28.074  74.022  1.00 33.15
ATOM   2061  CZ  TYR   245      22.272  28.088  73.590  1.00 33.02
ATOM   2062  OH  TYR   245      21.742  26.970  73.015  1.00 33.79
ATOM   2063  N   ARG   246      22.652  29.286  78.254  1.00 38.34
ATOM   2064  CA  ARG   246      23.014  28.147  79.083  1.00 40.81
ATOM   2065  C   ARG   246      23.300  26.871  78.284  1.00 40.92
ATOM   2066  O   ARG   246      22.580  26.507  77.352  1.00 40.45
ATOM   2067  CB  ARG   246      21.885  27.945  80.082  1.00 43.53
ATOM   2068  CG  ARG   246      21.774  26.552  80.704  1.00 47.61
ATOM   2069  CD  ARG   246      20.795  25.662  79.894  1.00 50.87
ATOM   2070  NE  ARG   246      21.225  24.262  79.735  1.00 53.84
ATOM   2071  CZ  ARG   246      21.206  23.635  78.538  1.00 55.26
ATOM   2072  NH1 ARG   246      20.802  24.295  77.447  1.00 56.48
ATOM   2073  NH2 ARG   246      21.564  22.346  78.427  1.00 55.10
ATOM   2074  N   GLY   247      24.367  26.184  78.707  1.00 41.18
ATOM   2075  CA  GLY   247      24.852  24.937  78.133  1.00 41.16
ATOM   2076  C   GLY   247      24.592  23.766  79.085  1.00 41.67
ATOM   2077  O   GLY   247      23.785  23.869  80.012  1.00 41.15
ATOM   2078  N   VAL   248      25.266  22.621  78.943  1.00 42.55
ATOM   2079  CA  VAL   248      24.929  21.484  79.801  1.00 43.21
ATOM   2080  C   VAL   248      25.339  21.805  81.208  1.00 43.71
ATOM   2081  O   VAL   248      24.563  21.699  82.154  1.00 44.56
ATOM   2082  CB  VAL   248      25.640  20.197  79.432  1.00 42.28
ATOM   2083  CG1 VAL   248      25.045  19.054  80.237  1.00 42.02
ATOM   2084  CG2 VAL   248      25.461  19.928  77.975  1.00 42.35
ATOM   2085  N   PHE   249      26.597  22.212  81.269  1.00 44.02
ATOM   2086  CA  PHE   249      27.179  22.531  82.547  1.00 44.67
ATOM   2087  C   PHE   249      27.302  24.074  82.621  1.00 45.63
ATOM   2088  O   PHE   249      27.070  24.708  83.657  1.00 46.46
ATOM   2089  CB  PHE   249      28.551  21.812  82.628  1.00 44.32
ATOM   2090  CG  PHE   249      28.664  20.385  82.044  1.00 44.24
ATOM   2091  CD1 PHE   249      28.018  19.290  82.644  1.00 44.05
ATOM   2092  CD2 PHE   249      29.416  20.166  80.875  1.00 44.24
ATOM   2093  CE1 PHE   249      28.128  18.012  82.073  1.00 43.81
ATOM   2094  CE2 PHE   249      29.516  18.880  80.317  1.00 44.12
ATOM   2095  CZ  PHE   249      28.873  17.801  80.913  1.00 43.60
ATOM   2096  N   LYS   250      27.644  24.732  81.503  1.00 45.38
ATOM   2097  CA  LYS   250      27.960  26.146  81.490  1.00 44.96
ATOM   2098  C   LYS   250      26.805  27.129  81.420  1.00 44.52
ATOM   2099  O   LYS   250      25.633  26.794  81.251  1.00 45.20
ATOM   2100  CB  LYS   250      28.844  26.405  80.308  1.00 46.01
ATOM   2101  CG  LYS   250      30.133  25.603  80.180  1.00 46.97
ATOM   2102  CD  LYS   250      31.267  26.259  80.934  1.00 47.82
ATOM   2103  CE  LYS   250      31.461  27.668  80.397  1.00 48.06
ATOM   2104  NZ  LYS   250      32.555  28.287  81.118  1.00 49.44
ATOM   2105  N   THR   251      27.135  28.404  81.538  1.00 43.37
ATOM   2106  CA  THR   251      26.276  29.496  81.139  1.00 42.31
ATOM   2107  C   THR   251      27.327  30.354  80.463  1.00 41.89
ATOM   2108  O   THR   251      28.337  30.690  81.073  1.00 42.90
ATOM   2109  CB  THR   251      25.692  30.206  82.314  1.00 42.30
ATOM   2110  OG1 THR   251      24.828  29.237  82.897  1.00 43.38
ATOM   2111  CG2 THR   251      24.959  31.501  81.953  1.00 41.75
ATOM   2112  N   TYR   252      27.194  30.576  79.168  1.00 40.59
ATOM   2113  CA  TYR   252      28.150  31.308  78.381  1.00 39.28
ATOM   2114  C   TYR   252      27.779  32.775  78.395  1.00 39.59
ATOM   2115  O   TYR   252      26.598  33.112  78.344  1.00 39.59
ATOM   2116  CB  TYR   252      28.126  30.743  77.000  1.00 37.63
ATOM   2117  CG  TYR   252      28.385  29.250  76.965  1.00 36.19
ATOM   2118  CD1 TYR   252      29.642  28.761  76.626  1.00 36.41
ATOM   2119  CE1 TYR   252      29.855  27.392  76.447  1.00 35.86
ATOM   2120  CD2 TYR   252      27.337  28.371  77.151  1.00 35.77
ATOM   2121  CE2 TYR   252      27.534  27.016  76.975  1.00 35.89
ATOM   2122  CZ  TYR   252      28.787  26.527  76.620  1.00 35.88
ATOM   2123  OH  TYR   252      28.952  25.153  76.441  1.00 36.72
ATOM   2124  N   ARG   253      28.786  33.622  78.583  1.00 40.15
ATOM   2125  CA  ARG   253      28.602  35.046  78.670  1.00 41.31
ATOM   2126  C   ARG   253      29.242  35.510  77.399  1.00 41.13
ATOM   2127  O   ARG   253      30.416  35.242  77.161  1.00 41.82
ATOM   2128  CB  ARG   253      29.325  35.657  79.867  1.00 42.38
ATOM   2129  CG  ARG   253      28.488  35.832  81.137  1.00 44.13
ATOM   2130  CD  ARG   253      28.229  34.542  81.876  1.00 46.52
ATOM   2131  NE  ARG   253      27.708  34.771  83.221  1.00 48.69
ATOM   2132  CZ  ARG   253      27.779  33.816  84.180  1.00 49.89
ATOM   2133  NH1 ARG   253      28.329  32.605  83.974  1.00 50.01
ATOM   2134  NH2 ARG   253      27.281  34.063  85.392  1.00 50.61
ATOM   2135  N   ILE   254      28.425  36.130  76.562  1.00 40.87
ATOM   2136  CA  ILE   254      28.775  36.594  75.232  1.00 40.13
ATOM   2137  C   ILE   254      28.341  38.060  75.272  1.00 39.24
ATOM   2138  O   ILE   254      27.540  38.405  76.157  1.00 38.06
ATOM   2139  CB  ILE   254      28.004  35.644  74.148  1.00 41.22
ATOM   2140  CG2 ILE   254      26.664  34.990  74.653  1.00 40.23
ATOM   2141  CG1 ILE   254      27.816  36.504  72.894  1.00 41.63
ATOM   2142  CD1 ILE   254      26.493  36.270  72.132  1.00 42.40
ATOM   2143  N   PRO   255      28.868  39.004  74.440  1.00 38.98
ATOM   2144  CA  PRO   255      28.411  40.400  74.416  1.00 38.43
ATOM   2145  C   PRO   255      26.971  40.440  73.993  1.00 37.33
ATOM   2146  O   PRO   255      26.519  39.522  73.310  1.00 37.94
ATOM   2147  CB  PRO   255      29.307  41.137  73.440  1.00 37.88
ATOM   2148  CG  PRO   255      30.578  40.397  73.631  1.00 38.08
ATOM   2149  CD  PRO   255      30.105  38.931  73.671  1.00 38.41
ATOM   2150  N   GLN   256      26.283  41.481  74.409  1.00 35.82
ATOM   2151  CA  GLN   256      24.906  41.673  74.032  1.00 35.08
ATOM   2152  C   GLN   256      24.971  42.271  72.620  1.00 34.57
ATOM   2153  O   GLN   256      25.815  43.176  72.379  1.00 34.40
ATOM   2154  CB  GLN   256      24.268  42.636  74.999  1.00 35.80
ATOM   2155  CG  GLN   256      24.589  42.217  76.409  1.00 38.05
ATOM   2156  CD  GLN   256      23.925  42.986  77.547  1.00 39.86
ATOM   2157  OE1 GLN   256      23.544  44.167  77.475  1.00 40.01
ATOM   2158  NE2 GLN   256      23.810  42.253  78.666  1.00 41.40
ATOM   2159  N   SER   257      24.217  41.758  71.629  1.00 32.72
ATOM   2160  CA  SER   257      24.183  42.470  70.361  1.00 31.82
ATOM   2161  C   SER   257      22.762  42.761  70.019  1.00 30.68
ATOM   2162  O   SER   257      22.074  43.247  70.908  1.00 32.06
ATOM   2163  CB  SER   257      24.836  41.689  69.226  1.00 32.44
ATOM   2164  OG  SER   257      24.586  40.304  69.309  1.00 34.14
ATOM   2165  N   ASP   258      22.229  42.517  68.831  1.00 29.03
ATOM   2166  CA  ASP   258      20.874  42.866  68.517  1.00 26.09
ATOM   2167  C   ASP   258      20.577  42.172  67.189  1.00 25.47
ATOM   2168  O   ASP   258      21.455  41.592  66.535  1.00 23.11
ATOM   2169  CB  ASP   258      20.842  44.362  68.406  1.00 26.04
ATOM   2170  CG  ASP   258      19.562  45.090  68.736  1.00 26.22
ATOM   2171  OD1 ASP   258      19.637  46.301  68.808  1.00 27.35
ATOM   2172  OD2 ASP   258      18.508  44.504  68.899  1.00 25.55
ATOM   2173  N   ALA   259      19.310  42.168  66.780  1.00 25.28
ATOM   2174  CA  ALA   259      18.871  41.640  65.492  1.00 24.44
ATOM   2175  C   ALA   259      17.923  42.749  65.055  1.00 24.71
ATOM   2176  O   ALA   259      17.070  43.147  65.848  1.00 24.51
ATOM   2177  CB  ALA   259      18.094  40.325  65.650  1.00 22.27
ATOM   2178  N   ASP   260      18.147  43.354  63.878  1.00 24.88
ATOM   2179  CA  ASP   260      17.225  44.331  63.290  1.00 24.48
ATOM   2180  C   ASP   260      15.891  43.732  62.808  1.00 24.11
ATOM   2181  O   ASP   260      14.907  44.443  62.673  1.00 25.62
ATOM   2182  CB  ASP   260      17.991  45.041  62.160  1.00 25.02
ATOM   2183  CG  ASP   260      19.252  45.774  62.658  1.00 25.53
ATOM   2184  OD1 ASP   260      19.203  46.373  63.749  1.00 25.43
ATOM   2185  OD2 ASP   260      20.276  45.754  61.960  1.00 24.72
ATOM   2186  N   PHE   261      15.773  42.418  62.606  1.00 22.21
ATOM   2187  CA  PHE   261      14.542  41.709  62.299  1.00 19.87
ATOM   2188  C   PHE   261      14.783  40.253  62.670  1.00 20.03
ATOM   2189  O   PHE   261      15.950  39.842  62.633  1.00 19.96
ATOM   2190  CB  PHE   261      14.199  41.747  60.795  1.00 16.67
ATOM   2191  CG  PHE   261      15.238  41.183  59.797  1.00 13.39
ATOM   2192  CD1 PHE   261      16.276  42.000  59.310  1.00 12.35
ATOM   2193  CD2 PHE   261      15.147  39.862  59.349  1.00 12.00
ATOM   2194  CE1 PHE   261      17.190  41.482  58.397  1.00 10.64
ATOM   2195  CE2 PHE   261      16.070  39.358  58.438  1.00  9.09
ATOM   2196  CZ  PHE   261      17.070  40.164  57.978  1.00  9.63
ATOM   2197  N   ILE   262      13.768  39.432  62.994  1.00 21.13
ATOM   2198  CA  ILE   262      13.939  37.979  63.160  1.00 21.07
ATOM   2199  C   ILE   262      13.223  37.374  61.966  1.00 20.80
ATOM   2200  O   ILE   262      12.064  37.736  61.716  1.00 21.36
ATOM   2201  CB  ILE   262      13.305  37.486  64.497  1.00 21.65
ATOM   2202  CG2 ILE   262      13.181  35.960  64.589  1.00 21.45
ATOM   2203  CG1 ILE   262      14.242  37.948  65.614  1.00 22.44
ATOM   2204  CD1 ILE   262      13.536  38.614  66.790  1.00 23.37
ATOM   2205  N   GLY   263      13.897  36.583  61.145  1.00 19.23
ATOM   2206  CA  GLY   263      13.245  35.827  60.105  1.00 16.91
ATOM   2207  C   GLY   263      12.558  34.627  60.766  1.00 16.54
ATOM   2208  O   GLY   263      13.195  33.974  61.611  1.00 16.19
ATOM   2209  N   VAL   264      11.269  34.307  60.501  1.00 14.90
ATOM   2210  CA  VAL   264      10.635  33.179  61.138  1.00 12.09
ATOM   2211  C   VAL   264      10.569  32.138  60.073  1.00 13.36
ATOM   2212  O   VAL   264      10.080  32.471  59.011  1.00 15.54
ATOM   2213  CB  VAL   264       9.267  33.463  61.566  1.00  9.81
ATOM   2214  CG1 VAL   264       8.696  32.214  62.187  1.00  8.51
ATOM   2215  CG2 VAL   264       9.253  34.526  62.616  1.00  9.16
ATOM   2216  N   ASN   265      11.097  30.942  60.225  1.00 12.70
ATOM   2217  CA  ASN   265      10.938  29.887  59.276  1.00 12.33
ATOM   2218  C   ASN   265       9.881  28.996  59.901  1.00 14.09
ATOM   2219  O   ASN   265      10.195  28.389  60.922  1.00 15.21
ATOM   2220  CB  ASN   265      12.194  29.055  59.087  1.00 10.80
ATOM   2221  CG  ASN   265      13.254  29.779  58.294  1.00 11.13
ATOM   2222  OD1 ASN   265      13.143  30.967  57.943  1.00 11.49
ATOM   2223  ND2 ASN   265      14.347  29.124  57.936  1.00 10.18
ATOM   2224  N   TYR   266       8.629  28.879  59.407  1.00 15.58
ATOM   2225  CA  TYR   266       7.631  28.004  59.992  1.00 15.61
ATOM   2226  C   TYR   266       7.240  26.920  59.007  1.00 16.44
ATOM   2227  O   TYR   266       7.004  27.176  57.846  1.00 17.36
ATOM   2228  CB  TYR   266       6.420  28.776  60.358  1.00 15.49
ATOM   2229  CG  TYR   266       5.294  27.851  60.818  1.00 15.62
ATOM   2230  CD1 TYR   266       5.363  27.324  62.099  1.00 15.13
ATOM   2231  CE1 TYR   266       4.367  26.471  62.562  1.00 15.49
ATOM   2232  CD2 TYR   266       4.202  27.527  59.985  1.00 15.66
ATOM   2233  CE2 TYR   266       3.195  26.675  60.459  1.00 14.94
ATOM   2234  CZ  TYR   266       3.303  26.159  61.734  1.00 15.25
ATOM   2235  OH  TYR   266       2.390  25.271  62.217  1.00 15.79
ATOM   2236  N   TYR   267       7.165  25.670  59.453  1.00 17.43
ATOM   2237  CA  TYR   267       6.828  24.531  58.651  1.00 16.24
ATOM   2238  C   TYR   267       5.787  23.693  59.315  1.00 16.43
ATOM   2239  O   TYR   267       4.706  23.564  58.720  1.00 17.39
ATOM   2240  CB  TYR   267       8.020  23.642  58.389  1.00 16.03
ATOM   2241  CG  TYR   267       8.837  24.298  57.310  1.00 17.06
ATOM   2242  CD1 TYR   267       8.609  23.906  55.986  1.00 17.83
ATOM   2243  CE1 TYR   267       9.343  24.508  54.957  1.00 18.29
ATOM   2244  CD2 TYR   267       9.791  25.289  57.612  1.00 16.65
ATOM   2245  CE2 TYR   267      10.527  25.893  56.587  1.00 17.05
ATOM   2246  CZ  TYR   267      10.298  25.486  55.272  1.00 17.75
ATOM   2247  OH  TYR   267      11.082  25.971  54.251  1.00 18.65
ATOM   2248  N   THR   268       6.048  23.136  60.501  1.00 15.66
ATOM   2249  CA  THR   268       5.105  22.223  61.108  1.00 14.71
ATOM   2250  C   THR   268       5.089  22.340  62.630  1.00 16.12
ATOM   2251  O   THR   268       5.591  23.332  63.194  1.00 16.18
ATOM   2252  CB  THR   268       5.450  20.799  60.595  1.00 14.22
ATOM   2253  OG1 THR   268       4.506  19.887  61.183  1.00 12.88
ATOM   2254  CG2 THR   268       6.862  20.406  60.905  1.00 13.80
ATOM   2255  N   ALA   269       4.370  21.447  63.319  1.00 17.55
ATOM   2256  CA  ALA   269       4.434  21.412  64.778  1.00 18.58
ATOM   2257  C   ALA   269       4.961  20.000  65.216  1.00 19.50
ATOM   2258  O   ALA   269       4.862  18.998  64.456  1.00 18.53
ATOM   2259  CB  ALA   269       3.023  21.718  65.310  1.00 16.03
ATOM   2260  N   SER   270       5.548  19.939  66.427  1.00 20.77
ATOM   2261  CA  SER   270       6.091  18.747  67.062  1.00 22.46
ATOM   2262  C   SER   270       5.404  18.533  68.385  1.00 24.00
ATOM   2263  O   SER   270       4.864  19.458  68.999  1.00 25.23
ATOM   2264  CB  SER   270       7.521  18.902  67.370  1.00 23.02
ATOM   2265  OG  SER   270       8.267  19.056  66.170  1.00 25.40
ATOM   2266  N   GLU   271       5.366  17.296  68.819  1.00 25.77
ATOM   2267  CA  GLU   271       4.836  16.911  70.096  1.00 27.98
ATOM   2268  C   GLU   271       6.010  16.418  70.976  1.00 27.50
ATOM   2269  O   GLU   271       6.973  15.809  70.498  1.00 27.50
ATOM   2270  CB  GLU   271       3.816  15.838  69.849  1.00 30.48
ATOM   2271  CG  GLU   271       2.423  16.416  69.916  1.00 34.91
ATOM   2272  CD  GLU   271       1.331  15.367  69.671  1.00 37.81
ATOM   2273  OE1 GLU   271       1.485  14.249  70.200  1.00 39.52
ATOM   2274  OE2 GLU   271       0.349  15.649  68.948  1.00 38.55
ATOM   2275  N   VAL   272       5.988  16.693  72.271  1.00 26.56
ATOM   2276  CA  VAL   272       7.069  16.402  73.181  1.00 25.91
ATOM   2277  C   VAL   272       6.508  15.674  74.396  1.00 26.85
ATOM   2278  O   VAL   272       5.597  16.155  75.067  1.00 25.16
ATOM   2279  CB  VAL   272       7.745  17.768  73.564  1.00 24.60
ATOM   2280  CG1 VAL   272       8.704  17.616  74.713  1.00 23.97
ATOM   2281  CG2 VAL   272       8.588  18.261  72.436  1.00 23.51
ATOM   2282  N   ARG   273       6.934  14.456  74.661  1.00 29.88
ATOM   2283  CA  ARG   273       6.594  13.832  75.915  1.00 33.25
ATOM   2284  C   ARG   273       7.821  13.863  76.829  1.00 33.26
ATOM   2285  O   ARG   273       8.978  14.036  76.458  1.00 31.78
ATOM   2286  CB  ARG   273       6.128  12.363  75.732  1.00 35.74
ATOM   2287  CG  ARG   273       7.175  11.339  75.276  1.00 39.45
ATOM   2288  CD  ARG   273       6.706   9.858  75.279  1.00 41.49
ATOM   2289  NE  ARG   273       7.877   8.972  75.201  1.00 43.60
ATOM   2290  CZ  ARG   273       8.523   8.537  76.308  1.00 44.22
ATOM   2291  NH1 ARG   273       8.120   8.897  77.540  1.00 44.36
ATOM   2292  NH2 ARG   273       9.577   7.713  76.193  1.00 44.50
ATOM   2293  N   HIS   274       7.557  13.667  78.088  1.00 34.46
ATOM   2294  CA  HIS   274       8.594  13.578  79.087  1.00 36.14
ATOM   2295  C   HIS   274       9.380  12.256  79.019  1.00 35.80
ATOM   2296  O   HIS   274       8.806  11.250  78.639  1.00 35.00
ATOM   2297  CB  HIS   274       7.913  13.738  80.406  1.00 37.44
ATOM   2298  CG  HIS   274       8.921  13.716  81.506  1.00 38.91
ATOM   2299  CD2 HIS   274       9.853  14.712  81.658  1.00 39.38
ATOM   2300  ND1 HIS   274       9.088  12.774  82.435  1.00 39.23
ATOM   2301  CE1 HIS   274      10.106  13.176  83.158  1.00 39.93
ATOM   2302  NE2 HIS   274      10.556  14.331  82.683  1.00 40.17
ATOM   2303  N   THR   275      10.688  12.210  79.321  1.00 36.18
ATOM   2304  CA  THR   275      11.434  10.959  79.443  1.00 35.60
ATOM   2305  C   THR   275      12.239  11.055  80.718  1.00 34.16
ATOM   2306  O   THR   275      12.335  12.128  81.319  1.00 33.00
ATOM   2307  CB  THR   275      12.514  10.659  78.390  1.00 36.74
ATOM   2308  OG1 THR   275      12.559  11.626  77.351  1.00 37.63
ATOM   2309  CG2 THR   275      12.268   9.238  77.943  1.00 36.92
ATOM   2310  N   TRP   276      12.780   9.913  81.142  1.00 33.67
ATOM   2311  CA  TRP   276      13.694   9.878  82.283  1.00 33.40
ATOM   2312  C   TRP   276      15.148  10.138  81.837  1.00 33.19
ATOM   2313  O   TRP   276      15.981  10.447  82.673  1.00 32.96
ATOM   2314  CB  TRP   276      13.652   8.513  83.002  1.00 31.99
ATOM   2315  CG  TRP   276      14.070   7.375  82.081  1.00 31.94
ATOM   2316  CD2 TRP   276      15.369   7.019  81.766  1.00 32.00
ATOM   2317  CE2 TRP   276      15.164   6.069  80.786  1.00 31.46
ATOM   2318  CE3 TRP   276      16.667   7.364  82.149  1.00 31.71
ATOM   2319  CD1 TRP   276      13.144   6.666  81.380  1.00 31.11
ATOM   2320  NE1 TRP   276      13.851   5.894  80.598  1.00 30.69
ATOM   2321  CZ2 TRP   276      16.262   5.467  80.187  1.00 32.07
ATOM   2322  CZ3 TRP   276      17.749   6.760  81.545  1.00 31.06
ATOM   2323  CH2 TRP   276      17.546   5.818  80.567  1.00 31.17
ATOM   2324  N   ASN   277      15.506  10.005  80.558  1.00 32.42
ATOM   2325  CA  ASN   277      16.878  10.015  80.164  1.00 32.67
ATOM   2326  C   ASN   277      17.484  11.387  80.098  1.00 33.72
ATOM   2327  O   ASN   277      17.144  12.122  79.165  1.00 35.39
ATOM   2328  CB  ASN   277      17.003   9.326  78.821  1.00 33.21
ATOM   2329  CG  ASN   277      18.465   9.031  78.461  1.00 34.69
ATOM   2330  OD1 ASN   277      19.362   9.853  78.635  1.00 34.55
ATOM   2331  ND2 ASN   277      18.847   7.872  77.962  1.00 35.11
ATOM   2332  N   PRO   278      18.423  11.805  80.962  1.00 33.72
ATOM   2333  CA  PRO   278      19.063  13.121  80.901  1.00 32.87
ATOM   2334  C   PRO   278      19.861  13.420  79.648  1.00 32.04
ATOM   2335  O   PRO   278      20.231  14.555  79.394  1.00 31.86
ATOM   2336  CB  PRO   278      19.878  13.150  82.153  1.00 32.79
ATOM   2337  CG  PRO   278      20.195  11.706  82.394  1.00 33.08
ATOM   2338  CD  PRO   278      18.910  11.039  82.093  1.00 32.84
ATOM   2339  N   LEU   279      20.167  12.429  78.824  1.00 32.34
ATOM   2340  CA  LEU   279      20.914  12.640  77.588  1.00 32.56
ATOM   2341  C   LEU   279      19.981  13.279  76.585  1.00 32.78
ATOM   2342  O   LEU   279      20.433  14.137  75.825  1.00 34.07
ATOM   2343  CB  LEU   279      21.454  11.303  77.018  1.00 32.50
ATOM   2344  CG  LEU   279      22.476  10.505  77.848  1.00 32.09
ATOM   2345  CD1 LEU   279      22.511   9.071  77.339  1.00 32.42
ATOM   2346  CD2 LEU   279      23.847  11.135  77.751  1.00 31.93
ATOM   2347  N   LYS   280      18.681  12.877  76.645  1.00 32.73
ATOM   2348  CA  LYS   280      17.563  13.415  75.861  1.00 31.18
ATOM   2349  C   LYS   280      17.008  14.653  76.509  1.00 29.94
ATOM   2350  O   LYS   280      15.938  15.091  76.169  1.00 30.87
ATOM   2351  CB  LYS   280      16.416  12.458  75.765  1.00 31.13
ATOM   2352  CG  LYS   280      16.807  11.266  74.974  1.00 33.35
ATOM   2353  CD  LYS   280      15.554  10.469  74.596  1.00 35.00
ATOM   2354  CE  LYS   280      15.902   9.248  73.722  1.00 35.35
ATOM   2355  NZ  LYS   280      14.764   8.872  72.884  1.00 36.36
ATOM   2356  N   PHE   281      17.688  15.268  77.439  1.00 29.13
ATOM   2357  CA  PHE   281      17.231  16.368  78.238  1.00 29.62
ATOM   2358  C   PHE   281      15.867  16.122  78.862  1.00 30.21
ATOM   2359  O   PHE   281      15.146  17.049  79.199  1.00 29.84
ATOM   2360  CB  PHE   281      17.264  17.632  77.381  1.00 30.96
ATOM   2361  CG  PHE   281      18.620  17.866  76.728  1.00 32.31
ATOM   2362  CD1 PHE   281      18.747  17.768  75.356  1.00 33.41
ATOM   2363  CD2 PHE   281      19.756  18.124  77.486  1.00 33.44
ATOM   2364  CE1 PHE   281      20.001  17.914  74.744  1.00 34.65
ATOM   2365  CE2 PHE   281      21.012  18.272  76.872  1.00 34.18
ATOM   2366  CZ  PHE   281      21.144  18.167  75.494  1.00 34.43
ATOM   2367  N   PHE   282      15.535  14.860  79.159  1.00 31.19
ATOM   2368  CA  PHE   282      14.250  14.467  79.742  1.00 33.03
ATOM   2369  C   PHE   282      12.953  14.753  78.950  1.00 33.93
ATOM   2370  O   PHE   282      11.877  15.018  79.524  1.00 33.59
ATOM   2371  CB  PHE   282      14.083  15.094  81.121  1.00 34.29
ATOM   2372  CG  PHE   282      15.212  14.809  82.087  1.00 35.70
ATOM   2373  CD1 PHE   282      16.203  15.774  82.284  1.00 35.92
ATOM   2374  CD2 PHE   282      15.246  13.594  82.774  1.00 36.10
ATOM   2375  CE1 PHE   282      17.230  15.510  83.177  1.00 36.47
ATOM   2376  CE2 PHE   282      16.274  13.332  83.660  1.00 36.49
ATOM   2377  CZ  PHE   282      17.264  14.290  83.862  1.00 37.04
ATOM   2378  N   PHE   283      13.026  14.652  77.613  1.00 34.84
ATOM   2379  CA  PHE   283      11.887  14.729  76.704  1.00 35.12
ATOM   2380  C   PHE   283      12.118  14.060  75.370  1.00 36.10
ATOM   2381  O   PHE   283      13.208  14.087  74.821  1.00 36.16
ATOM   2382  CB  PHE   283      11.450  16.157  76.390  1.00 33.57
ATOM   2383  CG  PHE   283      12.462  17.225  76.060  1.00 32.00
ATOM   2384  CD1 PHE   283      13.129  17.221  74.850  1.00 31.94
ATOM   2385  CD2 PHE   283      12.677  18.235  76.996  1.00 31.67
ATOM   2386  CE1 PHE   283      14.030  18.243  74.566  1.00 31.71
ATOM   2387  CE2 PHE   283      13.568  19.249  76.714  1.00 31.03
ATOM   2388  CZ  PHE   283      14.243  19.254  75.503  1.00 31.38
ATOM   2389  N   GLU   284      11.096  13.384  74.873  1.00 38.22
ATOM   2390  CA  GLU   284      11.106  12.776  73.560  1.00 40.00
ATOM   2391  C   GLU   284      10.175  13.560  72.604  1.00 39.27
ATOM   2392  O   GLU   284       8.995  13.769  72.894  1.00 38.74
ATOM   2393  CB  GLU   284      10.661  11.334  73.726  1.00 42.75
ATOM   2394  CG  GLU   284      11.862  10.400  73.841  1.00 46.15
ATOM   2395  CD  GLU   284      11.553   8.920  74.087  1.00 48.18
ATOM   2396  OE1 GLU   284      12.341   8.245  74.757  1.00 49.38
ATOM   2397  OE2 GLU   284      10.522   8.424  73.612  1.00 49.66
ATOM   2398  N   VAL   285      10.715  14.021  71.470  1.00 38.32
ATOM   2399  CA  VAL   285      10.007  14.774  70.439  1.00 37.39
ATOM   2400  C   VAL   285       9.532  13.869  69.297  1.00 37.74
ATOM   2401  O   VAL   285      10.208  12.904  68.904  1.00 38.05
ATOM   2402  CB  VAL   285      10.937  15.829  69.888  1.00 36.97
ATOM   2403  CG1 VAL   285      10.264  16.675  68.828  1.00 36.66
ATOM   2404  CG2 VAL   285      11.396  16.679  71.052  1.00 36.69
ATOM   2405  N   LYS   286       8.366  14.167  68.730  1.00 37.45
ATOM   2406  CA  LYS   286       7.798  13.463  67.589  1.00 36.78
ATOM   2407  C   LYS   286       7.133  14.557  66.789  1.00 35.48
ATOM   2408  O   LYS   286       6.952  15.667  67.284  1.00 35.28
ATOM   2409  CB  LYS   286       6.743  12.375  67.992  1.00 38.16
ATOM   2410  CG  LYS   286       5.804  12.567  69.198  1.00 40.70
ATOM   2411  CD  LYS   286       6.636  12.561  70.539  1.00 42.83
ATOM   2412  CE  LYS   286       5.927  12.686  71.887  1.00 43.06
ATOM   2413  NZ  LYS   286       5.489  11.367  72.335  1.00 44.08
ATOM   2414  N   LEU   287       6.792  14.303  65.525  1.00 34.81
ATOM   2415  CA  LEU   287       6.118  15.251  64.627  1.00 32.77
ATOM   2416  C   LEU   287       4.669  15.255  65.091  1.00 31.09
ATOM   2417  O   LEU   287       4.192  14.159  65.321  1.00 30.03
ATOM   2418  CB  LEU   287       6.281  14.695  63.235  1.00 32.89
ATOM   2419  CG  LEU   287       7.009  15.417  62.109  1.00 33.10
ATOM   2420  CD1 LEU   287       7.899  16.477  62.641  1.00 32.20
ATOM   2421  CD2 LEU   287       7.848  14.407  61.330  1.00 33.34
ATOM   2422  N   ALA   288       3.909  16.334  65.307  1.00 30.43
ATOM   2423  CA  ALA   288       2.525  16.222  65.774  1.00 30.26
ATOM   2424  C   ALA   288       1.651  15.726  64.651  1.00 30.82
ATOM   2425  O   ALA   288       1.926  16.013  63.482  1.00 30.82
ATOM   2426  CB  ALA   288       1.936  17.545  66.198  1.00 29.50
ATOM   2427  N   ASP   289       0.631  14.938  64.958  1.00 32.03
ATOM   2428  CA  ASP   289      -0.250  14.435  63.921  1.00 33.09
ATOM   2429  C   ASP   289      -1.456  15.323  64.039  1.00 32.73
ATOM   2430  O   ASP   289      -2.317  15.111  64.896  1.00 32.51
ATOM   2431  CB  ASP   289      -0.649  12.999  64.189  1.00 35.13
ATOM   2432  CG  ASP   289      -1.278  12.316  62.983  1.00 37.02
ATOM   2433  OD1 ASP   289      -2.432  12.583  62.662  1.00 38.25
ATOM   2434  OD2 ASP   289      -0.601  11.510  62.345  1.00 38.85
ATOM   2435  N   ILE   290      -1.460  16.387  63.276  1.00 32.42
ATOM   2436  CA  ILE   290      -2.600  17.256  63.341  1.00 33.45
ATOM   2437  C   ILE   290      -3.462  17.035  62.100  1.00 34.17
ATOM   2438  O   ILE   290      -4.657  16.702  62.201  1.00 33.50
ATOM   2439  CB  ILE   290      -2.120  18.735  63.468  1.00 33.26
ATOM   2440  CG2 ILE   290      -3.305  19.733  63.520  1.00 33.65
ATOM   2441  CG1 ILE   290      -1.310  18.839  64.739  1.00 32.63
ATOM   2442  CD1 ILE   290      -0.968  20.261  65.157  1.00 32.29
ATOM   2443  N   SER   291      -2.875  17.172  60.914  1.00 34.89
ATOM   2444  CA  SER   291      -3.656  17.088  59.727  1.00 35.82
ATOM   2445  C   SER   291      -3.660  15.631  59.339  1.00 36.95
ATOM   2446  O   SER   291      -2.629  14.980  59.441  1.00 36.09
ATOM   2447  CB  SER   291      -3.024  17.982  58.659  1.00 36.30
ATOM   2448  OG  SER   291      -1.693  17.689  58.250  1.00 36.32
ATOM   2449  N   GLU   292      -4.831  15.129  58.905  1.00 38.55
ATOM   2450  CA  GLU   292      -4.986  13.751  58.448  1.00 39.58
ATOM   2451  C   GLU   292      -4.119  13.571  57.202  1.00 38.65
ATOM   2452  O   GLU   292      -3.739  12.458  56.851  1.00 38.25
ATOM   2453  CB  GLU   292      -6.486  13.420  58.080  1.00 41.80
ATOM   2454  CG  GLU   292      -7.727  13.825  58.968  1.00 45.09
ATOM   2455  CD  GLU   292      -7.987  13.122  60.335  1.00 47.73
ATOM   2456  OE1 GLU   292      -8.358  13.783  61.353  1.00 47.49
ATOM   2457  OE2 GLU   292      -7.824  11.882  60.348  1.00 48.57
ATOM   2458  N   ARG   293      -3.796  14.651  56.485  1.00 38.15
ATOM   2459  CA  ARG   293      -3.023  14.580  55.255  1.00 38.02
ATOM   2460  C   ARG   293      -1.597  15.089  55.488  1.00 37.69
ATOM   2461  O   ARG   293      -1.407  16.189  56.019  1.00 37.49
ATOM   2462  CB  ARG   293      -3.767  15.417  54.212  1.00 38.27
ATOM   2463  CG  ARG   293      -3.185  15.071  52.862  1.00 38.85
ATOM   2464  CD  ARG   293      -3.822  15.637  51.596  1.00 38.70
ATOM   2465  NE  ARG   293      -2.907  15.152  50.572  1.00 38.77
ATOM   2466  CZ  ARG   293      -2.851  15.624  49.336  1.00 38.55
ATOM   2467  NH1 ARG   293      -3.660  16.601  48.934  1.00 37.77
ATOM   2468  NH2 ARG   293      -1.928  15.091  48.525  1.00 38.52
ATOM   2469  N   LYS   294      -0.560  14.353  55.095  1.00 37.60
ATOM   2470  CA  LYS   294       0.803  14.743  55.445  1.00 37.09
ATOM   2471  C   LYS   294       1.662  15.205  54.293  1.00 37.34
ATOM   2472  O   LYS   294       1.295  14.918  53.163  1.00 38.75
ATOM   2473  CB  LYS   294       1.486  13.585  56.146  1.00 35.97
ATOM   2474  CG  LYS   294       1.202  13.574  57.644  1.00 34.99
ATOM   2475  CD  LYS   294      -0.108  12.908  57.966  1.00 35.15
ATOM   2476  CE  LYS   294      -0.460  12.750  59.444  1.00 34.78
ATOM   2477  NZ  LYS   294      -0.199  14.001  60.116  1.00 35.58
ATOM   2478  N   THR   295       2.733  15.970  54.511  1.00 37.18
ATOM   2479  CA  THR   295       3.681  16.408  53.476  1.00 37.03
ATOM   2480  C   THR   295       4.604  15.273  52.960  1.00 37.88
ATOM   2481  O   THR   295       4.666  14.208  53.588  1.00 38.88
ATOM   2482  CB  THR   295       4.376  17.580  54.181  1.00 35.88
ATOM   2483  OG1 THR   295       3.402  18.576  54.032  1.00 35.30
ATOM   2484  CG2 THR   295       5.680  18.108  53.661  1.00 36.20
ATOM   2485  N   GLN   296       5.370  15.361  51.870  1.00 38.15
ATOM   2486  CA  GLN   296       6.311  14.295  51.497  1.00 38.70
ATOM   2487  C   GLN   296       7.357  13.989  52.589  1.00 39.95
ATOM   2488  O   GLN   296       8.141  13.030  52.441  1.00 40.91
ATOM   2489  CB  GLN   296       7.110  14.648  50.249  1.00 37.97
ATOM   2490  CG  GLN   296       6.397  14.555  48.941  1.00 36.71
ATOM   2491  CD  GLN   296       7.292  15.081  47.839  1.00 36.73
ATOM   2492  OE1 GLN   296       7.469  16.285  47.692  1.00 36.20
ATOM   2493  NE2 GLN   296       7.898  14.234  47.032  1.00 36.72
ATOM   2494  N   MET   297       7.502  14.845  53.634  1.00 39.50
ATOM   2495  CA  MET   297       8.336  14.462  54.780  1.00 39.30
ATOM   2496  C   MET   297       7.475  13.913  55.935  1.00 37.60
ATOM   2497  O   MET   297       7.939  13.777  57.066  1.00 38.34
ATOM   2498  CB  MET   297       9.177  15.640  55.339  1.00 40.46
ATOM   2499  CG  MET   297       9.054  16.971  54.655  1.00 41.91
ATOM   2500  SD  MET   297      10.115  17.219  53.218  1.00 45.38
ATOM   2501  CE  MET   297      11.701  17.336  54.027  1.00 43.20
ATOM   2502  N   GLY   298       6.197  13.591  55.704  1.00 34.98
ATOM   2503  CA  GLY   298       5.295  13.109  56.724  1.00 31.02
ATOM   2504  C   GLY   298       4.948  14.176  57.727  1.00 29.23
ATOM   2505  O   GLY   298       4.448  13.886  58.808  1.00 29.23
ATOM   2506  N   TRP   299       5.178  15.433  57.409  1.00 27.30
ATOM   2507  CA  TRP   299       4.786  16.480  58.316  1.00 26.34
ATOM   2508  C   TRP   299       3.295  16.832  58.244  1.00 25.45
ATOM   2509  O   TRP   299       2.696  16.798  57.173  1.00 25.15
ATOM   2510  CB  TRP   299       5.560  17.751  58.031  1.00 25.57
ATOM   2511  CG  TRP   299       7.055  17.662  58.108  1.00 25.63
ATOM   2512  CD2 TRP   299       7.871  18.649  57.647  1.00 25.53
ATOM   2513  CE2 TRP   299       9.142  18.081  57.832  1.00 25.45
ATOM   2514  CE3 TRP   299       7.715  19.914  57.100  1.00 24.81
ATOM   2515  CD1 TRP   299       7.756  16.568  58.572  1.00 25.87
ATOM   2516  NE1 TRP   299       9.023  16.857  58.377  1.00 25.46
ATOM   2517  CZ2 TRP   299      10.267  18.793  57.451  1.00 25.33
ATOM   2518  CZ3 TRP   299       8.862  20.616  56.721  1.00 25.18
ATOM   2519  CH2 TRP   299      10.128  20.066  56.891  1.00 24.87
ATOM   2520  N   SER   300       2.677  17.178  59.351  1.00 24.87
ATOM   2521  CA  SER   300       1.352  17.727  59.320  1.00 25.61
ATOM   2522  C   SER   300       1.428  19.120  58.743  1.00 26.13
ATOM   2523  O   SER   300       2.515  19.679  58.588  1.00 27.10
ATOM   2524  CB  SER   300       0.750  17.829  60.703  1.00 25.89
ATOM   2525  OG  SER   300       0.493  16.537  61.292  1.00 27.07
ATOM   2526  N   VAL   301       0.272  19.655  58.391  1.00 26.17
ATOM   2527  CA  VAL   301       0.125  20.986  57.880  1.00 25.41
ATOM   2528  C   VAL   301      -0.694  21.595  59.004  1.00 25.55
ATOM   2529  O   VAL   301      -1.567  20.921  59.546  1.00 26.53
ATOM   2530  CB  VAL   301      -0.592  20.906  56.518  1.00 24.92
ATOM   2531  CG1 VAL   301      -1.045  22.284  56.053  1.00 25.00
ATOM   2532  CG2 VAL   301       0.403  20.436  55.444  1.00 23.90
ATOM   2533  N   TYR   302      -0.412  22.817  59.449  1.00 25.26
ATOM   2534  CA  TYR   302      -1.069  23.370  60.607  1.00 25.55
ATOM   2535  C   TYR   302      -1.043  24.858  60.430  1.00 25.64
ATOM   2536  O   TYR   302      -0.243  25.490  61.098  1.00 27.18
ATOM   2537  CB  TYR   302      -0.307  22.956  61.895  1.00 26.39
ATOM   2538  CG  TYR   302      -0.818  23.531  63.205  1.00 27.32
ATOM   2539  CD1 TYR   302      -2.169  23.421  63.562  1.00 28.35
ATOM   2540  CE1 TYR   302      -2.652  23.956  64.759  1.00 29.16
ATOM   2541  CD2 TYR   302       0.067  24.175  64.052  1.00 27.72
ATOM   2542  CE2 TYR   302      -0.398  24.705  65.255  1.00 29.48
ATOM   2543  CZ  TYR   302      -1.760  24.598  65.617  1.00 30.25
ATOM   2544  OH  TYR   302      -2.200  25.075  66.855  1.00 31.16
ATOM   2545  N   PRO   303      -1.840  25.542  59.603  1.00 25.33
ATOM   2546  CA  PRO   303      -1.722  26.966  59.291  1.00 23.51
ATOM   2547  C   PRO   303      -1.704  27.990  60.388  1.00 22.28
ATOM   2548  O   PRO   303      -1.133  29.053  60.222  1.00 21.60
ATOM   2549  CB  PRO   303      -2.845  27.169  58.315  1.00 24.06
ATOM   2550  CG  PRO   303      -2.733  25.869  57.528  1.00 23.80
ATOM   2551  CD  PRO   303      -2.814  24.933  58.713  1.00 24.65
ATOM   2552  N   LYS   304      -2.338  27.663  61.489  1.00 22.07
ATOM   2553  CA  LYS   304      -2.426  28.505  62.650  1.00 23.08
ATOM   2554  C   LYS   304      -1.096  28.643  63.361  1.00 22.66
ATOM   2555  O   LYS   304      -0.811  29.671  63.966  1.00 22.58
ATOM   2556  CB  LYS   304      -3.445  27.923  63.600  1.00 24.34
ATOM   2557  CG  LYS   304      -3.871  28.985  64.597  1.00 26.29
ATOM   2558  CD  LYS   304      -4.992  28.443  65.439  1.00 28.42
ATOM   2559  CE  LYS   304      -4.628  27.087  66.047  1.00 30.20
ATOM   2560  NZ  LYS   304      -5.495  26.812  67.204  1.00 33.34
ATOM   2561  N   GLY   305      -0.243  27.633  63.267  1.00 22.57
ATOM   2562  CA  GLY   305       1.102  27.659  63.838  1.00 22.52
ATOM   2563  C   GLY   305       1.938  28.814  63.338  1.00 21.92
ATOM   2564  O   GLY   305       2.660  29.396  64.102  1.00 21.86
ATOM   2565  N   ILE   306       1.830  29.252  62.094  1.00 22.70
ATOM   2566  CA  ILE   306       2.531  30.413  61.571  1.00 22.12
ATOM   2567  C   ILE   306       2.080  31.671  62.293  1.00 22.91
ATOM   2568  O   ILE   306       2.835  32.641  62.317  1.00 23.39
ATOM   2569  CB  ILE   306       2.261  30.479  60.045  1.00 21.58
ATOM   2570  CG2 ILE   306       0.934  31.165  59.726  1.00 21.17
ATOM   2571  CG1 ILE   306       3.398  31.217  59.391  1.00 20.69
ATOM   2572  CD1 ILE   306       3.262  31.356  57.864  1.00 19.50
ATOM   2573  N   TYR   307       0.872  31.677  62.890  1.00 22.87
ATOM   2574  CA  TYR   307       0.382  32.856  63.601  1.00 22.52
ATOM   2575  C   TYR   307       0.903  32.823  65.025  1.00 22.64
ATOM   2576  O   TYR   307       1.206  33.874  65.581  1.00 22.20
ATOM   2577  CB  TYR   307      -1.150  32.875  63.589  1.00 21.34
ATOM   2578  CG  TYR   307      -1.795  33.983  64.411  1.00 20.94
ATOM   2579  CD1 TYR   307      -1.951  35.276  63.949  1.00 21.01
ATOM   2580  CE1 TYR   307      -2.535  36.254  64.752  1.00 20.72
ATOM   2581  CD2 TYR   307      -2.229  33.676  65.683  1.00 21.93
ATOM   2582  CE2 TYR   307      -2.796  34.644  66.494  1.00 21.75
ATOM   2583  CZ  TYR   307      -2.943  35.929  66.026  1.00 21.36
ATOM   2584  OH  TYR   307      -3.438  36.875  66.911  1.00 21.99
ATOM   2585  N   MET   308       0.963  31.627  65.625  1.00 23.04
ATOM   2586  CA  MET   308       1.499  31.433  66.971  1.00 24.18
ATOM   2587  C   MET   308       3.041  31.626  66.889  1.00 24.47
ATOM   2588  O   MET   308       3.625  32.346  67.708  1.00 24.91
ATOM   2589  CB  MET   308       1.110  30.005  67.521  1.00 23.55
ATOM   2590  CG  MET   308      -0.373  29.679  67.848  1.00 23.29
ATOM   2591  SD  MET   308      -0.637  27.866  67.890  1.00 25.14
ATOM   2592  CE  MET   308      -1.828  27.749  69.174  1.00 24.51
ATOM   2593  N   ALA   309       3.727  31.145  65.855  1.00 23.67
ATOM   2594  CA  ALA   309       5.148  31.342  65.621  1.00 23.34
ATOM   2595  C   ALA   309       5.517  32.801  65.646  1.00 23.24
ATOM   2596  O   ALA   309       6.442  33.267  66.278  1.00 24.74
ATOM   2597  CB  ALA   309       5.549  30.834  64.264  1.00 22.41
ATOM   2598  N   LEU   310       4.700  33.581  65.007  1.00 24.26
ATOM   2599  CA  LEU   310       4.905  34.997  64.807  1.00 23.90
ATOM   2600  C   LEU   310       4.538  35.778  66.071  1.00 24.30
ATOM   2601  O   LEU   310       5.117  36.816  66.381  1.00 23.86
ATOM   2602  CB  LEU   310       4.044  35.205  63.561  1.00 22.82
ATOM   2603  CG  LEU   310       4.202  36.141  62.412  1.00 21.96
ATOM   2604  CD1 LEU   310       5.625  36.268  61.972  1.00 22.20
ATOM   2605  CD2 LEU   310       3.353  35.600  61.293  1.00 20.99
ATOM   2606  N   LYS   311       3.549  35.311  66.831  1.00 25.59
ATOM   2607  CA  LYS   311       3.093  35.964  68.046  1.00 27.11
ATOM   2608  C   LYS   311       4.161  35.735  69.094  1.00 27.26
ATOM   2609  O   LYS   311       4.596  36.672  69.774  1.00 28.25
ATOM   2610  CB  LYS   311       1.817  35.335  68.463  1.00 29.27
ATOM   2611  CG  LYS   311       1.185  35.767  69.742  1.00 31.65
ATOM   2612  CD  LYS   311       0.606  37.180  69.639  1.00 34.59
ATOM   2613  CE  LYS   311      -0.224  37.442  70.929  1.00 36.83
ATOM   2614  NZ  LYS   311       0.450  37.026  72.179  1.00 37.51
ATOM   2615  N   LYS   312       4.578  34.481  69.221  1.00 25.87
ATOM   2616  CA  LYS   312       5.727  34.089  70.045  1.00 25.26
ATOM   2617  C   LYS   312       6.954  34.913  69.707  1.00 23.20
ATOM   2618  O   LYS   312       7.455  35.616  70.567  1.00 24.01
ATOM   2619  CB  LYS   312       6.073  32.602  69.835  1.00 26.24
ATOM   2620  CG  LYS   312       5.134  31.753  70.688  1.00 26.03
ATOM   2621  CD  LYS   312       5.373  30.326  70.347  1.00 27.69
ATOM   2622  CE  LYS   312       5.090  29.523  71.600  1.00 28.69
ATOM   2623  NZ  LYS   312       5.086  28.102  71.254  1.00 30.47
ATOM   2624  N   ALA   313       7.398  34.965  68.472  1.00 20.72
ATOM   2625  CA  ALA   313       8.544  35.740  68.129  1.00 19.41
ATOM   2626  C   ALA   313       8.368  37.224  68.301  1.00 20.05
ATOM   2627  O   ALA   313       9.375  37.927  68.305  1.00 20.81
ATOM   2628  CB  ALA   313       8.902  35.411  66.721  1.00 19.19
ATOM   2629  N   SER   314       7.162  37.785  68.545  1.00 21.30
ATOM   2630  CA  SER   314       6.991  39.235  68.638  1.00 21.26
ATOM   2631  C   SER   314       7.443  39.777  69.985  1.00 22.37
ATOM   2632  O   SER   314       7.500  40.992  70.239  1.00 21.58
ATOM   2633  CB  SER   314       5.534  39.597  68.411  1.00 22.22
ATOM   2634  OG  SER   314       4.535  39.454  69.447  1.00 23.81
ATOM   2635  N   ARG   315       7.805  38.837  70.864  1.00 22.97
ATOM   2636  CA  ARG   315       8.254  39.170  72.173  1.00 23.47
ATOM   2637  C   ARG   315       9.469  40.082  72.158  1.00 24.33
ATOM   2638  O   ARG   315       9.561  40.954  73.032  1.00 24.87
ATOM   2639  CB  ARG   315       8.541  37.878  72.911  1.00 23.57
ATOM   2640  CG  ARG   315       9.571  36.943  72.335  1.00 23.49
ATOM   2641  CD  ARG   315       9.693  35.752  73.264  1.00 23.03
ATOM   2642  NE  ARG   315       8.514  34.914  73.321  1.00 23.73
ATOM   2643  CZ  ARG   315       8.466  33.813  74.084  1.00 24.81
ATOM   2644  NH1 ARG   315       9.512  33.482  74.822  1.00 26.38
ATOM   2645  NH2 ARG   315       7.440  32.944  74.055  1.00 24.57
ATOM   2646  N   TYR   316      10.358  39.969  71.148  1.00 24.66
ATOM   2647  CA  TYR   316      11.596  40.769  71.105  1.00 24.72
ATOM   2648  C   TYR   316      11.522  42.188  70.578  1.00 25.58
ATOM   2649  O   TYR   316      12.580  42.783  70.315  1.00 26.91
ATOM   2650  CB  TYR   316      12.648  40.052  70.282  1.00 24.41
ATOM   2651  CG  TYR   316      12.878  38.670  70.829  1.00 24.55
ATOM   2652  CD1 TYR   316      12.503  37.560  70.090  1.00 25.15
ATOM   2653  CE1 TYR   316      12.687  36.278  70.629  1.00 26.65
ATOM   2654  CD2 TYR   316      13.433  38.521  72.093  1.00 24.78
ATOM   2655  CE2 TYR   316      13.619  37.250  72.640  1.00 25.81
ATOM   2656  CZ  TYR   316      13.246  36.138  71.906  1.00 25.91
ATOM   2657  OH  TYR   316      13.416  34.894  72.450  1.00 26.30
ATOM   2658  N   GLY   317      10.294  42.702  70.333  1.00 25.83
ATOM   2659  CA  GLY   317      10.017  44.038  69.799  1.00 24.62
ATOM   2660  C   GLY   317      10.706  44.346  68.484  1.00 24.98
ATOM   2661  O   GLY   317      11.081  45.506  68.252  1.00 25.06
ATOM   2662  N   ARG   318      10.873  43.356  67.590  1.00 25.65
ATOM   2663  CA  ARG   318      11.581  43.596  66.320  1.00 26.07
ATOM   2664  C   ARG   318      10.770  43.103  65.130  1.00 24.69
ATOM   2665  O   ARG   318      10.124  42.068  65.276  1.00 24.66
ATOM   2666  CB  ARG   318      12.936  42.858  66.204  1.00 27.23
ATOM   2667  CG  ARG   318      14.162  43.080  67.070  1.00 27.73
ATOM   2668  CD  ARG   318      14.583  44.490  66.953  1.00 28.52
ATOM   2669  NE  ARG   318      14.140  45.023  68.213  1.00 31.25
ATOM   2670  CZ  ARG   318      14.965  45.669  69.043  1.00 32.50
ATOM   2671  NH1 ARG   318      16.245  45.864  68.750  1.00 32.66
ATOM   2672  NH2 ARG   318      14.497  46.090  70.220  1.00 33.71
ATOM   2673  N   PRO   319      10.795  43.759  63.955  1.00 24.73
ATOM   2674  CA  PRO   319      10.036  43.370  62.748  1.00 24.35
ATOM   2675  C   PRO   319      10.257  41.943  62.324  1.00 24.32
ATOM   2676  O   PRO   319      11.405  41.454  62.339  1.00 24.34
ATOM   2677  CB  PRO   319      10.456  44.357  61.666  1.00 23.96
ATOM   2678  CG  PRO   319      11.672  45.088  62.213  1.00 24.28
ATOM   2679  CD  PRO   319      11.482  45.044  63.728  1.00 24.35
ATOM   2680  N   LEU   320       9.176  41.304  61.901  1.00 23.70
ATOM   2681  CA  LEU   320       9.272  39.887  61.564  1.00 24.19
ATOM   2682  C   LEU   320       9.109  39.622  60.069  1.00 24.86
ATOM   2683  O   LEU   320       8.516  40.441  59.353  1.00 25.44
ATOM   2684  CB  LEU   320       8.201  39.107  62.348  1.00 23.44
ATOM   2685  CG  LEU   320       8.214  39.273  63.881  1.00 23.23
ATOM   2686  CD1 LEU   320       6.878  38.937  64.516  1.00 21.79
ATOM   2687  CD2 LEU   320       9.338  38.388  64.408  1.00 23.52
ATOM   2688  N   TYR   321       9.670  38.527  59.543  1.00 24.68
ATOM   2689  CA  TYR   321       9.430  38.098  58.186  1.00 24.66
ATOM   2690  C   TYR   321       9.122  36.628  58.271  1.00 23.75
ATOM   2691  O   TYR   321       9.417  36.030  59.307  1.00 24.74
ATOM   2692  CB  TYR   321      10.636  38.220  57.260  1.00 26.10
ATOM   2693  CG  TYR   321      11.091  39.642  57.052  1.00 27.39
ATOM   2694  CD1 TYR   321      10.706  40.300  55.890  1.00 27.43
ATOM   2695  CE1 TYR   321      11.055  41.645  55.717  1.00 28.57
ATOM   2696  CD2 TYR   321      11.836  40.305  58.050  1.00 27.63
ATOM   2697  CE2 TYR   321      12.182  41.644  57.881  1.00 27.92
ATOM   2698  CZ  TYR   321      11.784  42.305  56.718  1.00 29.34
ATOM   2699  OH  TYR   321      12.049  43.657  56.578  1.00 31.08
ATOM   2700  N   ILE   322       8.449  35.995  57.310  1.00 21.88
ATOM   2701  CA  ILE   322       8.448  34.551  57.293  1.00 19.99
ATOM   2702  C   ILE   322       9.440  34.455  56.163  1.00 18.63
ATOM   2703  O   ILE   322       9.296  35.136  55.150  1.00 19.72
ATOM   2704  CB  ILE   322       7.094  33.897  56.926  1.00 19.86
ATOM   2705  CG2 ILE   322       7.229  32.456  56.460  1.00 19.51
ATOM   2706  CG1 ILE   322       6.295  33.782  58.193  1.00 20.31
ATOM   2707  CD1 ILE   322       5.176  34.812  58.138  1.00 21.21
ATOM   2708  N   THR   323      10.541  33.776  56.442  1.00 17.07
ATOM   2709  CA  THR   323      11.669  33.680  55.549  1.00 15.03
ATOM   2710  C   THR   323      11.598  32.334  54.874  1.00 15.32
ATOM   2711  O   THR   323      12.265  32.154  53.853  1.00 16.07
ATOM   2712  CB  THR   323      13.040  33.930  56.374  1.00 13.45
ATOM   2713  OG1 THR   323      12.833  33.664  57.733  1.00 12.61
ATOM   2714  CG2 THR   323      13.487  35.371  56.347  1.00 11.22
ATOM   2715  N   GLU   324      10.781  31.402  55.375  1.00 15.49
ATOM   2716  CA  GLU   324      10.547  30.095  54.779  1.00 16.90
ATOM   2717  C   GLU   324       9.243  29.625  55.385  1.00 19.01
ATOM   2718  O   GLU   324       8.864  29.879  56.531  1.00 18.68
ATOM   2719  CB  GLU   324      11.482  28.990  55.148  1.00 16.33
ATOM   2720  CG  GLU   324      12.866  29.319  54.687  1.00 17.92
ATOM   2721  CD  GLU   324      13.902  28.230  54.831  1.00 18.02
ATOM   2722  OE1 GLU   324      15.090  28.511  54.782  1.00 18.32
ATOM   2723  OE2 GLU   324      13.536  27.079  54.960  1.00 19.63
ATOM   2724  N   ASN   325       8.513  28.992  54.495  1.00 21.88
ATOM   2725  CA  ASN   325       7.234  28.323  54.758  1.00 22.78
ATOM   2726  C   ASN   325       6.996  27.599  53.432  1.00 23.21
ATOM   2727  O   ASN   325       7.168  28.256  52.382  1.00 23.64
ATOM   2728  CB  ASN   325       6.156  29.335  55.002  1.00 23.21
ATOM   2729  CG  ASN   325       4.818  28.686  55.203  1.00 23.09
ATOM   2730  OD1 ASN   325       4.551  27.728  55.925  1.00 23.07
ATOM   2731  ND2 ASN   325       3.924  29.274  54.466  1.00 23.69
ATOM   2732  N   GLY   326       6.689  26.306  53.359  1.00 21.66
ATOM   2733  CA  GLY   326       6.680  25.681  52.053  1.00 21.84
ATOM   2734  C   GLY   326       6.161  24.292  52.224  1.00 22.77
ATOM   2735  O   GLY   326       6.056  23.865  53.382  1.00 22.46
ATOM   2736  N   ILE   327       5.759  23.598  51.137  1.00 23.38
ATOM   2737  CA  ILE   327       5.171  22.253  51.236  1.00 22.39
ATOM   2738  C   ILE   327       5.820  21.492  50.104  1.00 23.39
ATOM   2739  O   ILE   327       6.143  22.045  49.068  1.00 23.31
ATOM   2740  CB  ILE   327       3.550  22.331  51.150  1.00 20.68
ATOM   2741  CG2 ILE   327       3.085  23.002  49.894  1.00 20.03
ATOM   2742  CG1 ILE   327       2.963  20.947  51.244  1.00 19.78
ATOM   2743  CD1 ILE   327       1.549  20.848  51.813  1.00 17.18
ATOM   2744  N   ALA   328       6.165  20.257  50.389  1.00 25.49
ATOM   2745  CA  ALA   328       6.812  19.392  49.449  1.00 28.01
ATOM   2746  C   ALA   328       5.661  18.467  49.190  1.00 30.03
ATOM   2747  O   ALA   328       5.203  17.798  50.145  1.00 30.64
ATOM   2748  CB  ALA   328       7.946  18.562  50.068  1.00 27.65
ATOM   2749  N   THR   329       5.172  18.531  47.952  1.00 31.44
ATOM   2750  CA  THR   329       4.152  17.624  47.473  1.00 32.81
ATOM   2751  C   THR   329       4.392  17.460  46.006  1.00 33.72
ATOM   2752  O   THR   329       5.206  18.156  45.410  1.00 35.09
ATOM   2753  CB  THR   329       2.655  18.079  47.526  1.00 33.11
ATOM   2754  OG1 THR   329       2.547  19.483  47.701  1.00 34.71
ATOM   2755  CG2 THR   329       1.958  17.229  48.546  1.00 32.65
ATOM   2756  N   LEU   330       3.689  16.469  45.449  1.00 34.56
ATOM   2757  CA  LEU   330       3.555  16.378  44.007  1.00 34.02
ATOM   2758  C   LEU   330       2.193  17.013  43.632  1.00 34.24
ATOM   2759  O   LEU   330       1.953  17.623  42.580  1.00 35.95
ATOM   2760  CB  LEU   330       3.678  14.916  43.688  1.00 32.78
ATOM   2761  CG  LEU   330       5.030  14.325  44.089  1.00 31.79
ATOM   2762  CD1 LEU   330       4.959  12.881  43.716  1.00 32.05
ATOM   2763  CD2 LEU   330       6.208  14.956  43.400  1.00 29.85
ATOM   2764  N   ASP   331       1.253  17.028  44.567  1.00 32.95
ATOM   2765  CA  ASP   331      -0.054  17.618  44.340  1.00 31.57
ATOM   2766  C   ASP   331       0.049  19.117  44.487  1.00 30.46
ATOM   2767  O   ASP   331      -0.148  19.664  45.587  1.00 31.24
ATOM   2768  CB  ASP   331      -0.982  16.948  45.350  1.00 31.74
ATOM   2769  CG  ASP   331      -2.428  17.360  45.523  1.00 31.68
ATOM   2770  OD1 ASP   331      -2.839  18.439  45.105  1.00 31.48
ATOM   2771  OD2 ASP   331      -3.138  16.575  46.140  1.00 31.81
ATOM   2772  N   ASP   332       0.303  19.799  43.373  1.00 28.56
ATOM   2773  CA  ASP   332       0.326  21.247  43.414  1.00 27.92
ATOM   2774  C   ASP   332      -0.965  21.933  43.882  1.00 27.55
ATOM   2775  O   ASP   332      -1.024  23.143  44.116  1.00 26.57
ATOM   2776  CB  ASP   332       0.692  21.733  42.058  1.00 28.41
ATOM   2777  CG  ASP   332       1.155  23.174  42.090  1.00 30.38
ATOM   2778  OD1 ASP   332       2.216  23.416  42.642  1.00 32.64
ATOM   2779  OD2 ASP   332       0.478  24.072  41.609  1.00 31.02
ATOM   2780  N   GLU   333      -2.056  21.181  44.052  1.00 27.84
ATOM   2781  CA  GLU   333      -3.315  21.755  44.465  1.00 27.90
ATOM   2782  C   GLU   333      -3.268  21.933  45.960  1.00 27.66
ATOM   2783  O   GLU   333      -3.769  22.971  46.390  1.00 27.02
ATOM   2784  CB  GLU   333      -4.477  20.816  44.021  1.00 29.57
ATOM   2785  CG  GLU   333      -5.791  21.500  43.559  1.00 28.74
ATOM   2786  CD  GLU   333      -5.554  22.601  42.527  1.00 29.04
ATOM   2787  OE1 GLU   333      -4.787  22.415  41.580  1.00 29.88
ATOM   2788  OE2 GLU   333      -6.136  23.659  42.659  1.00 27.94
ATOM   2789  N   TRP   334      -2.601  20.983  46.689  1.00 27.39
ATOM   2790  CA  TRP   334      -2.273  21.049  48.144  1.00 26.94
ATOM   2791  C   TRP   334      -1.437  22.333  48.391  1.00 25.95
ATOM   2792  O   TRP   334      -1.724  23.191  49.233  1.00 25.20
ATOM   2793  CB  TRP   334      -1.477  19.776  48.525  1.00 27.01
ATOM   2794  CG  TRP   334      -1.388  19.263  49.976  1.00 27.75
ATOM   2795  CD2 TRP   334      -2.101  19.616  51.091  1.00 27.79
ATOM   2796  CE2 TRP   334      -1.607  18.693  52.060  1.00 28.34
ATOM   2797  CE3 TRP   334      -3.068  20.534  51.430  1.00 27.74
ATOM   2798  CD1 TRP   334      -0.521  18.215  50.289  1.00 28.63
ATOM   2799  NE1 TRP   334      -0.662  17.875  51.558  1.00 28.48
ATOM   2800  CZ2 TRP   334      -2.069  18.669  53.358  1.00 27.86
ATOM   2801  CZ3 TRP   334      -3.539  20.523  52.740  1.00 29.31
ATOM   2802  CH2 TRP   334      -3.054  19.605  53.686  1.00 29.27
ATOM   2803  N   ARG   335      -0.412  22.563  47.583  1.00 25.73
ATOM   2804  CA  ARG   335       0.378  23.791  47.654  1.00 25.73
ATOM   2805  C   ARG   335      -0.407  25.095  47.563  1.00 27.00
ATOM   2806  O   ARG   335      -0.095  26.043  48.306  1.00 28.10
ATOM   2807  CB  ARG   335       1.445  23.748  46.543  1.00 24.20
ATOM   2808  CG  ARG   335       2.421  24.919  46.358  1.00 24.46
ATOM   2809  CD  ARG   335       3.828  24.359  46.221  1.00 25.23
ATOM   2810  NE  ARG   335       3.792  23.358  45.195  1.00 27.60
ATOM   2811  CZ  ARG   335       4.421  22.197  45.247  1.00 28.45
ATOM   2812  NH1 ARG   335       5.170  21.879  46.304  1.00 28.31
ATOM   2813  NH2 ARG   335       4.226  21.336  44.220  1.00 28.85
ATOM   2814  N   VAL   336      -1.420  25.203  46.677  1.00 26.65
ATOM   2815  CA  VAL   336      -2.086  26.485  46.497  1.00 26.42
ATOM   2816  C   VAL   336      -2.781  26.858  47.805  1.00 26.77
ATOM   2817  O   VAL   336      -2.656  27.935  48.404  1.00 25.93
ATOM   2818  CB  VAL   336      -3.077  26.363  45.280  1.00 26.27
ATOM   2819  CG1 VAL   336      -3.697  27.733  45.023  1.00 26.52
ATOM   2820  CG2 VAL   336      -2.366  25.965  43.990  1.00 25.82
ATOM   2821  N   GLU   337      -3.410  25.802  48.273  1.00 27.97
ATOM   2822  CA  GLU   337      -4.129  25.764  49.508  1.00 30.16
ATOM   2823  C   GLU   337      -3.265  26.105  50.701  1.00 30.28
ATOM   2824  O   GLU   337      -3.691  26.941  51.499  1.00 31.50
ATOM   2825  CB  GLU   337      -4.697  24.399  49.662  1.00 32.10
ATOM   2826  CG  GLU   337      -5.906  24.616  50.461  1.00 35.26
ATOM   2827  CD  GLU   337      -6.685  23.354  50.665  1.00 37.84
ATOM   2828  OE1 GLU   337      -7.847  23.322  50.237  1.00 39.90
ATOM   2829  OE2 GLU   337      -6.145  22.433  51.287  1.00 39.20
ATOM   2830  N   PHE   338      -2.061  25.506  50.815  1.00 30.57
ATOM   2831  CA  PHE   338      -1.055  25.780  51.860  1.00 29.07
ATOM   2832  C   PHE   338      -0.732  27.257  51.905  1.00 27.65
ATOM   2833  O   PHE   338      -0.767  27.866  52.978  1.00 27.79
ATOM   2834  CB  PHE   338       0.260  25.007  51.578  1.00 30.12
ATOM   2835  CG  PHE   338       1.367  24.998  52.664  1.00 29.59
ATOM   2836  CD1 PHE   338       1.438  23.918  53.573  1.00 28.89
ATOM   2837  CD2 PHE   338       2.303  26.051  52.753  1.00 28.70
ATOM   2838  CE1 PHE   338       2.425  23.887  54.554  1.00 27.91
ATOM   2839  CE2 PHE   338       3.276  25.997  53.743  1.00 28.05
ATOM   2840  CZ  PHE   338       3.338  24.929  54.635  1.00 27.60
ATOM   2841  N   ILE   339      -0.453  27.843  50.754  1.00 26.20
ATOM   2842  CA  ILE   339      -0.084  29.225  50.681  1.00 25.44
ATOM   2843  C   ILE   339      -1.243  30.094  51.086  1.00 26.51
ATOM   2844  O   ILE   339      -1.015  31.049  51.824  1.00 27.81
ATOM   2845  CB  ILE   339       0.378  29.557  49.250  1.00 25.16
ATOM   2846  CG2 ILE   339       0.782  31.036  49.158  1.00 24.69
ATOM   2847  CG1 ILE   339       1.545  28.622  48.868  1.00 24.78
ATOM   2848  CD1 ILE   339       2.179  28.763  47.465  1.00 25.04
ATOM   2849  N   ILE   340      -2.502  29.857  50.745  1.00 27.13
ATOM   2850  CA  ILE   340      -3.564  30.821  51.109  1.00 27.02
ATOM   2851  C   ILE   340      -3.995  30.646  52.554  1.00 26.16
ATOM   2852  O   ILE   340      -4.309  31.612  53.256  1.00 26.08
ATOM   2853  CB  ILE   340      -4.760  30.639  50.049  1.00 28.60
ATOM   2854  CG2 ILE   340      -6.132  31.159  50.549  1.00 28.08
ATOM   2855  CG1 ILE   340      -4.287  31.347  48.750  1.00 28.37
ATOM   2856  CD1 ILE   340      -5.012  30.895  47.477  1.00 29.05
ATOM   2857  N   GLN   341      -4.058  29.422  53.051  1.00 24.54
ATOM   2858  CA  GLN   341      -4.240  29.214  54.466  1.00 24.52
ATOM   2859  C   GLN   341      -3.086  29.801  55.323  1.00 24.44
ATOM   2860  O   GLN   341      -3.281  30.424  56.368  1.00 24.14
ATOM   2861  CB  GLN   341      -4.375  27.752  54.641  1.00 25.60
ATOM   2862  CG  GLN   341      -5.762  27.436  54.254  1.00 27.07
ATOM   2863  CD  GLN   341      -6.064  25.989  54.426  1.00 28.33
ATOM   2864  OE1 GLN   341      -5.949  25.345  55.459  1.00 29.43
ATOM   2865  NE2 GLN   341      -6.552  25.425  53.377  1.00 30.20
ATOM   2866  N   HIS   342      -1.835  29.671  54.896  1.00 23.77
ATOM   2867  CA  HIS   342      -0.757  30.224  55.649  1.00 22.94
ATOM   2868  C   HIS   342      -0.886  31.689  55.447  1.00 22.48
ATOM   2869  O   HIS   342      -1.012  32.344  56.465  1.00 24.30
ATOM   2870  CB  HIS   342       0.572  29.645  55.175  1.00 21.95
ATOM   2871  CG  HIS   342       0.750  28.321  55.930  1.00 22.32
ATOM   2872  CD2 HIS   342       0.569  27.060  55.439  1.00 21.92
ATOM   2873  ND1 HIS   342       1.088  28.148  57.214  1.00 23.24
ATOM   2874  CE1 HIS   342       1.124  26.867  57.503  1.00 22.79
ATOM   2875  NE2 HIS   342       0.809  26.220  56.419  1.00 22.31
ATOM   2876  N   LEU   343      -1.017  32.286  54.284  1.00 22.38
ATOM   2877  CA  LEU   343      -1.137  33.719  54.216  1.00 22.13
ATOM   2878  C   LEU   343      -2.382  34.333  54.839  1.00 22.80
ATOM   2879  O   LEU   343      -2.369  35.542  55.141  1.00 23.44
ATOM   2880  CB  LEU   343      -1.028  34.095  52.819  1.00 22.14
ATOM   2881  CG  LEU   343       0.352  34.228  52.371  1.00 21.96
ATOM   2882  CD1 LEU   343       0.367  34.368  50.889  1.00 24.09
ATOM   2883  CD2 LEU   343       0.917  35.485  52.888  1.00 21.84
ATOM   2884  N   GLN   344      -3.434  33.560  55.105  1.00 22.81
ATOM   2885  CA  GLN   344      -4.574  34.119  55.789  1.00 24.84
ATOM   2886  C   GLN   344      -4.148  34.409  57.228  1.00 25.34
ATOM   2887  O   GLN   344      -4.340  35.494  57.761  1.00 25.73
ATOM   2888  CB  GLN   344      -5.725  33.135  55.793  1.00 25.85
ATOM   2889  CG  GLN   344      -6.554  33.087  54.525  1.00 26.28
ATOM   2890  CD  GLN   344      -7.550  31.962  54.635  1.00 26.73
ATOM   2891  OE1 GLN   344      -8.730  32.128  54.805  1.00 28.40
ATOM   2892  NE2 GLN   344      -7.199  30.697  54.523  1.00 26.92
ATOM   2893  N   TYR   345      -3.507  33.450  57.888  1.00 24.93
ATOM   2894  CA  TYR   345      -2.917  33.642  59.200  1.00 24.06
ATOM   2895  C   TYR   345      -1.807  34.735  59.285  1.00 23.32
ATOM   2896  O   TYR   345      -1.754  35.501  60.239  1.00 21.86
ATOM   2897  CB  TYR   345      -2.462  32.255  59.552  1.00 23.74
ATOM   2898  CG  TYR   345      -3.610  31.484  60.161  1.00 22.76
ATOM   2899  CD1 TYR   345      -4.073  30.321  59.564  1.00 22.53
ATOM   2900  CE1 TYR   345      -5.110  29.617  60.188  1.00 22.21
ATOM   2901  CD2 TYR   345      -4.174  31.950  61.356  1.00 22.35
ATOM   2902  CE2 TYR   345      -5.204  31.249  61.973  1.00 21.59
ATOM   2903  CZ  TYR   345      -5.659  30.084  61.384  1.00 21.59
ATOM   2904  OH  TYR   345      -6.635  29.340  62.031  1.00 23.07
ATOM   2905  N   VAL   346      -0.917  34.899  58.303  1.00 23.07
ATOM   2906  CA  VAL   346       0.043  35.998  58.226  1.00 23.09
ATOM   2907  C   VAL   346      -0.801  37.232  58.224  1.00 25.05
ATOM   2908  O   VAL   346      -0.550  38.131  59.011  1.00 28.54
ATOM   2909  CB  VAL   346       0.876  36.019  56.936  1.00 20.73
ATOM   2910  CG1 VAL   346       1.755  37.197  56.902  1.00 19.66
ATOM   2911  CG2 VAL   346       1.744  34.799  56.875  1.00 20.57
ATOM   2912  N   HIS   347      -1.854  37.333  57.440  1.00 27.36
ATOM   2913  CA  HIS   347      -2.743  38.499  57.478  1.00 28.28
ATOM   2914  C   HIS   347      -3.494  38.736  58.812  1.00 28.31
ATOM   2915  O   HIS   347      -3.698  39.889  59.203  1.00 29.30
ATOM   2916  CB  HIS   347      -3.730  38.339  56.331  1.00 29.49
ATOM   2917  CG  HIS   347      -4.563  39.579  56.083  1.00 30.07
ATOM   2918  CD2 HIS   347      -4.066  40.643  55.396  1.00 30.10
ATOM   2919  ND1 HIS   347      -5.801  39.865  56.492  1.00 29.75
ATOM   2920  CE1 HIS   347      -6.062  41.066  56.086  1.00 29.91
ATOM   2921  NE2 HIS   347      -5.020  41.516  55.434  1.00 30.47
ATOM   2922  N   LYS   348      -3.988  37.725  59.520  1.00 28.05
ATOM   2923  CA  LYS   348      -4.626  37.872  60.801  1.00 28.98
ATOM   2924  C   LYS   348      -3.538  38.381  61.698  1.00 31.20
ATOM   2925  O   LYS   348      -3.899  39.145  62.575  1.00 33.59
ATOM   2926  CB  LYS   348      -5.103  36.554  61.385  1.00 29.01
ATOM   2927  CG  LYS   348      -5.640  36.688  62.806  1.00 30.52
ATOM   2928  CD  LYS   348      -7.139  36.405  62.948  1.00 32.30
ATOM   2929  CE  LYS   348      -7.888  37.295  63.982  1.00 32.83
ATOM   2930  NZ  LYS   348      -8.085  38.654  63.481  1.00 32.17
ATOM   2931  N   ALA   349      -2.241  38.036  61.543  1.00 32.17
ATOM   2932  CA  ALA   349      -1.181  38.494  62.417  1.00 32.18
ATOM   2933  C   ALA   349      -1.123  39.984  62.314  1.00 32.88
ATOM   2934  O   ALA   349      -1.126  40.680  63.329  1.00 32.66
ATOM   2935  CB  ALA   349       0.182  37.978  62.001  1.00 31.64
ATOM   2936  N   ILE   350      -1.122  40.436  61.060  1.00 34.22
ATOM   2937  CA  ILE   350      -1.023  41.854  60.767  1.00 35.50
ATOM   2938  C   ILE   350      -2.198  42.625  61.300  1.00 37.37
ATOM   2939  O   ILE   350      -2.053  43.717  61.828  1.00 38.05
ATOM   2940  CB  ILE   350      -0.907  42.065  59.275  1.00 33.85
ATOM   2941  CG2 ILE   350      -1.000  43.533  58.928  1.00 34.11
ATOM   2942  CG1 ILE   350       0.416  41.516  58.835  1.00 32.94
ATOM   2943  CD1 ILE   350       0.706  41.737  57.350  1.00 32.06
ATOM   2944  N   GLU   351      -3.372  42.066  61.213  1.00 39.99
ATOM   2945  CA  GLU   351      -4.516  42.764  61.721  1.00 42.58
ATOM   2946  C   GLU   351      -4.480  42.858  63.227  1.00 42.38
ATOM   2947  O   GLU   351      -4.795  43.921  63.773  1.00 43.57
ATOM   2948  CB  GLU   351      -5.719  42.038  61.175  1.00 45.38
ATOM   2949  CG  GLU   351      -6.079  42.651  59.822  1.00 50.10
ATOM   2950  CD  GLU   351      -4.937  43.164  58.904  1.00 53.22
ATOM   2951  OE1 GLU   351      -4.224  42.322  58.319  1.00 54.41
ATOM   2952  OE2 GLU   351      -4.770  44.404  58.783  1.00 54.12
ATOM   2953  N   ASP   352      -4.018  41.823  63.923  1.00 41.02
ATOM   2954  CA  ASP   352      -3.951  41.876  65.360  1.00 39.88
ATOM   2955  C   ASP   352      -2.782  42.694  65.882  1.00 38.46
ATOM   2956  O   ASP   352      -2.578  42.725  67.100  1.00 40.39
ATOM   2957  CB  ASP   352      -3.922  40.441  65.887  1.00 40.85
ATOM   2958  CG  ASP   352      -5.247  39.695  65.689  1.00 42.41
ATOM   2959  OD1 ASP   352      -6.257  40.322  65.399  1.00 43.83
ATOM   2960  OD2 ASP   352      -5.307  38.473  65.817  1.00 43.25
ATOM   2961  N   GLY   353      -1.976  43.371  65.058  1.00 35.18
ATOM   2962  CA  GLY   353      -0.955  44.273  65.570  1.00 32.12
ATOM   2963  C   GLY   353       0.466  43.902  65.214  1.00 30.41
ATOM   2964  O   GLY   353       1.327  44.764  65.123  1.00 28.84
ATOM   2965  N   LEU   354       0.707  42.623  64.960  1.00 29.92
ATOM   2966  CA  LEU   354       2.014  42.033  64.759  1.00 29.39
ATOM   2967  C   LEU   354       2.765  42.581  63.587  1.00 30.29
ATOM   2968  O   LEU   354       2.327  42.395  62.464  1.00 31.68
ATOM   2969  CB  LEU   354       1.836  40.572  64.585  1.00 28.84
ATOM   2970  CG  LEU   354       1.725  39.711  65.831  1.00 29.05
ATOM   2971  CD1 LEU   354       0.860  40.345  66.878  1.00 28.86
ATOM   2972  CD2 LEU   354       1.133  38.374  65.447  1.00 28.79
ATOM   2973  N   ASP   355       3.921  43.195  63.795  1.00 30.32
ATOM   2974  CA  ASP   355       4.712  43.795  62.728  1.00 30.05
ATOM   2975  C   ASP   355       5.341  42.804  61.720  1.00 29.65
ATOM   2976  O   ASP   355       6.567  42.691  61.651  1.00 31.33
ATOM   2977  CB  ASP   355       5.748  44.677  63.467  1.00 30.39
ATOM   2978  CG  ASP   355       6.668  45.605  62.700  1.00 31.70
ATOM   2979  OD1 ASP   355       7.373  46.351  63.379  1.00 32.30
ATOM   2980  OD2 ASP   355       6.706  45.577  61.459  1.00 32.26
ATOM   2981  N   VAL   356       4.565  42.069  60.901  1.00 28.02
ATOM   2982  CA  VAL   356       5.068  41.169  59.877  1.00 25.60
ATOM   2983  C   VAL   356       5.243  41.934  58.573  1.00 25.14
ATOM   2984  O   VAL   356       4.327  42.611  58.121  1.00 26.36
ATOM   2985  CB  VAL   356       4.097  40.021  59.674  1.00 24.81
ATOM   2986  CG1 VAL   356       4.824  38.913  58.941  1.00 24.89
ATOM   2987  CG2 VAL   356       3.580  39.519  61.005  1.00 24.42
ATOM   2988  N   ARG   357       6.391  41.836  57.919  1.00 24.38
ATOM   2989  CA  ARG   357       6.704  42.602  56.726  1.00 23.07
ATOM   2990  C   ARG   357       6.956  41.851  55.401  1.00 21.54
ATOM   2991  O   ARG   357       7.130  42.460  54.326  1.00 21.27
ATOM   2992  CB  ARG   357       7.938  43.453  57.005  1.00 24.80
ATOM   2993  CG  ARG   357       7.763  44.326  58.214  1.00 26.43
ATOM   2994  CD  ARG   357       8.802  45.409  58.131  1.00 28.01
ATOM   2995  NE  ARG   357       8.699  46.108  59.381  1.00 29.60
ATOM   2996  CZ  ARG   357       9.438  47.172  59.732  1.00 30.88
ATOM   2997  NH1 ARG   357      10.373  47.731  58.952  1.00 30.08
ATOM   2998  NH2 ARG   357       9.240  47.648  60.974  1.00 32.65
ATOM   2999  N   GLY   358       7.011  40.527  55.376  1.00 18.51
ATOM   3000  CA  GLY   358       7.324  39.830  54.149  1.00 16.44
ATOM   3001  C   GLY   358       6.991  38.398  54.428  1.00 16.58
ATOM   3002  O   GLY   358       6.936  38.011  55.612  1.00 15.92
ATOM   3003  N   TYR   359       6.706  37.672  53.354  1.00 15.63
ATOM   3004  CA  TYR   359       6.442  36.244  53.401  1.00 14.92
ATOM   3005  C   TYR   359       7.324  35.678  52.275  1.00 14.13
ATOM   3006  O   TYR   359       7.239  36.191  51.150  1.00 14.93
ATOM   3007  CB  TYR   359       4.941  36.015  53.159  1.00 15.16
ATOM   3008  CG  TYR   359       4.549  34.559  52.974  1.00 15.22
ATOM   3009  CD1 TYR   359       4.530  34.040  51.682  1.00 15.94
ATOM   3010  CE1 TYR   359       4.220  32.696  51.471  1.00 15.75
ATOM   3011  CD2 TYR   359       4.253  33.738  54.063  1.00 15.08
ATOM   3012  CE2 TYR   359       3.951  32.396  53.865  1.00 15.79
ATOM   3013  CZ  TYR   359       3.932  31.881  52.561  1.00 16.77
ATOM   3014  OH  TYR   359       3.578  30.547  52.329  1.00 17.68
ATOM   3015  N   PHE   360       8.239  34.741  52.508  1.00 11.80
ATOM   3016  CA  PHE   360       9.016  34.223  51.420  1.00 12.16
ATOM   3017  C   PHE   360       8.592  32.777  51.275  1.00 13.40
ATOM   3018  O   PHE   360       8.488  32.099  52.297  1.00 14.76
ATOM   3019  CB  PHE   360      10.517  34.247  51.675  1.00 12.31
ATOM   3020  CG  PHE   360      11.071  35.653  51.749  1.00 11.93
ATOM   3021  CD1 PHE   360      10.812  36.466  52.875  1.00 11.87
ATOM   3022  CD2 PHE   360      11.805  36.122  50.685  1.00 11.19
ATOM   3023  CE1 PHE   360      11.297  37.767  52.914  1.00 12.09
ATOM   3024  CE2 PHE   360      12.290  37.439  50.729  1.00 12.32
ATOM   3025  CZ  PHE   360      12.040  38.261  51.834  1.00 11.75
ATOM   3026  N   TYR   361       8.269  32.272  50.067  1.00 12.09
ATOM   3027  CA  TYR   361       7.815  30.918  49.924  1.00 11.19
ATOM   3028  C   TYR   361       9.062  30.081  49.764  1.00 12.23
ATOM   3029  O   TYR   361       9.959  30.312  48.934  1.00 11.63
ATOM   3030  CB  TYR   361       6.895  30.699  48.642  1.00  7.79
ATOM   3031  CG  TYR   361       6.410  29.273  48.501  1.00  3.58
ATOM   3032  CD1 TYR   361       5.394  28.749  49.298  1.00  4.39
ATOM   3033  CE1 TYR   361       5.102  27.354  49.256  1.00  3.72
ATOM   3034  CD2 TYR   361       7.088  28.426  47.661  1.00  3.41
ATOM   3035  CE2 TYR   361       6.797  27.054  47.608  1.00  2.00
ATOM   3036  CZ  TYR   361       5.830  26.508  48.410  1.00  2.86
ATOM   3037  OH  TYR   361       5.712  25.106  48.499  1.00  3.88
ATOM   3038  N   TRP   362       9.041  28.997  50.495  1.00 13.80
ATOM   3039  CA  TRP   362      10.127  28.098  50.328  1.00 14.43
ATOM   3040  C   TRP   362       9.781  27.111  49.255  1.00 15.64
ATOM   3041  O   TRP   362       9.322  25.980  49.401  1.00 14.30
ATOM   3042  CB  TRP   362      10.560  27.302  51.608  1.00 13.88
ATOM   3043  CG  TRP   362      11.851  26.521  51.312  1.00 12.67
ATOM   3044  CD2 TRP   362      13.116  27.044  51.194  1.00 12.78
ATOM   3045  CE2 TRP   362      13.839  25.928  50.744  1.00 12.17
ATOM   3046  CE3 TRP   362      13.754  28.260  51.419  1.00 12.98
ATOM   3047  CD1 TRP   362      11.827  25.180  50.990  1.00 12.67
ATOM   3048  NE1 TRP   362      13.043  24.854  50.626  1.00 12.06
ATOM   3049  CZ2 TRP   362      15.199  25.998  50.501  1.00 12.02
ATOM   3050  CZ3 TRP   362      15.113  28.327  51.184  1.00 13.32
ATOM   3051  CH2 TRP   362      15.832  27.203  50.728  1.00 13.03
ATOM   3052  N   SER   363      10.667  27.764  48.511  1.00 19.41
ATOM   3053  CA  SER   363      11.353  27.497  47.313  1.00 22.59
ATOM   3054  C   SER   363      10.754  27.888  46.003  1.00 24.56
ATOM   3055  O   SER   363       9.715  27.404  45.574  1.00 26.83
ATOM   3056  CB  SER   363      11.735  26.046  47.326  1.00 22.56
ATOM   3057  OG  SER   363      13.089  26.198  46.881  1.00 24.09
ATOM   3058  N   PHE   364      11.428  28.859  45.398  1.00 25.78
ATOM   3059  CA  PHE   364      11.185  29.187  44.010  1.00 27.36
ATOM   3060  C   PHE   364      11.201  27.887  43.170  1.00 28.71
ATOM   3061  O   PHE   364      10.257  27.543  42.453  1.00 30.02
ATOM   3062  CB  PHE   364      12.276  30.143  43.524  1.00 26.68
ATOM   3063  CG  PHE   364      12.197  30.520  42.040  1.00 27.77
ATOM   3064  CD1 PHE   364      11.092  31.230  41.524  1.00 27.63
ATOM   3065  CD2 PHE   364      13.233  30.128  41.172  1.00 27.33
ATOM   3066  CE1 PHE   364      11.043  31.530  40.162  1.00 26.88
ATOM   3067  CE2 PHE   364      13.156  30.433  39.815  1.00 27.09
ATOM   3068  CZ  PHE   364      12.066  31.131  39.313  1.00 26.34
ATOM   3069  N   MET   365      12.227  27.068  43.264  1.00 29.21
ATOM   3070  CA  MET   365      12.335  25.897  42.436  1.00 28.65
ATOM   3071  C   MET   365      12.512  24.736  43.362  1.00 28.45
ATOM   3072  O   MET   365      12.970  24.877  44.505  1.00 27.33
ATOM   3073  CB  MET   365      13.559  25.887  41.614  1.00 30.82
ATOM   3074  CG  MET   365      13.929  26.976  40.620  1.00 31.86
ATOM   3075  SD  MET   365      15.717  26.833  40.533  1.00 31.96
ATOM   3076  CE  MET   365      16.332  28.042  41.678  1.00 31.94
ATOM   3077  N   ASP   366      12.136  23.565  42.875  1.00 28.70
ATOM   3078  CA  ASP   366      12.575  22.331  43.534  1.00 29.59
ATOM   3079  C   ASP   366      14.118  22.405  43.594  1.00 30.38
ATOM   3080  O   ASP   366      14.717  23.086  42.747  1.00 30.84
ATOM   3081  CB  ASP   366      12.152  21.124  42.705  1.00 28.74
ATOM   3082  CG  ASP   366      10.659  20.948  42.498  1.00 28.15
ATOM   3083  OD1 ASP   366       9.849  21.366  43.322  1.00 27.18
ATOM   3084  OD2 ASP   366      10.335  20.344  41.495  1.00 27.92
ATOM   3085  N   ASN   367      14.846  21.807  44.532  1.00 31.07
ATOM   3086  CA  ASN   367      16.302  22.007  44.615  1.00 30.70
ATOM   3087  C   ASN   367      16.811  20.908  45.473  1.00 31.26
ATOM   3088  O   ASN   367      16.020  20.031  45.803  1.00 31.91
ATOM   3089  CB  ASN   367      16.662  23.305  45.266  1.00 29.08
ATOM   3090  CG  ASN   367      15.924  23.519  46.562  1.00 29.26
ATOM   3091  OD1 ASN   367      15.897  22.725  47.507  1.00 30.02
ATOM   3092  ND2 ASN   367      15.259  24.655  46.602  1.00 29.34
ATOM   3093  N   TYR   368      18.083  20.868  45.846  1.00 32.66
ATOM   3094  CA  TYR   368      18.605  19.794  46.708  1.00 33.69
ATOM   3095  C   TYR   368      18.096  19.853  48.165  1.00 33.89
ATOM   3096  O   TYR   368      18.469  20.720  48.975  1.00 34.02
ATOM   3097  CB  TYR   368      20.141  19.884  46.636  1.00 34.04
ATOM   3098  CG  TYR   368      20.900  18.803  47.356  1.00 33.68
ATOM   3099  CD1 TYR   368      20.701  17.453  47.054  1.00 33.73
ATOM   3100  CE1 TYR   368      21.381  16.466  47.766  1.00 34.07
ATOM   3101  CD2 TYR   368      21.770  19.192  48.352  1.00 33.91
ATOM   3102  CE2 TYR   368      22.453  18.203  49.074  1.00 34.73
ATOM   3103  CZ  TYR   368      22.261  16.843  48.789  1.00 34.47
ATOM   3104  OH  TYR   368      22.902  15.884  49.572  1.00 34.52
ATOM   3105  N   GLU   369      17.247  18.934  48.582  1.00 33.67
ATOM   3106  CA  GLU   369      16.782  18.936  49.953  1.00 32.97
ATOM   3107  C   GLU   369      17.785  18.163  50.810  1.00 31.94
ATOM   3108  O   GLU   369      17.511  17.056  51.279  1.00 31.42
ATOM   3109  CB  GLU   369      15.359  18.319  50.003  1.00 33.55
ATOM   3110  CG  GLU   369      14.670  18.477  51.344  1.00 34.98
ATOM   3111  CD  GLU   369      14.863  19.860  51.996  1.00 36.02
ATOM   3112  OE1 GLU   369      15.359  19.854  53.109  1.00 36.90
ATOM   3113  OE2 GLU   369      14.559  20.930  51.440  1.00 36.38
ATOM   3114  N   TRP   370      18.999  18.724  50.969  1.00 31.18
ATOM   3115  CA  TRP   370      20.020  18.258  51.913  1.00 30.37
ATOM   3116  C   TRP   370      20.186  16.761  51.972  1.00 31.99
ATOM   3117  O   TRP   370      20.379  16.162  50.912  1.00 32.83
ATOM   3118  CB  TRP   370      19.693  18.796  53.328  1.00 28.17
ATOM   3119  CG  TRP   370      19.708  20.301  53.328  1.00 26.84
ATOM   3120  CD2 TRP   370      20.806  21.067  53.045  1.00 26.43
ATOM   3121  CE2 TRP   370      20.260  22.345  53.097  1.00 26.45
ATOM   3122  CE3 TRP   370      22.156  20.889  52.759  1.00 26.11
ATOM   3123  CD1 TRP   370      18.570  21.015  53.548  1.00 25.89
ATOM   3124  NE1 TRP   370      18.935  22.261  53.398  1.00 26.36
ATOM   3125  CZ2 TRP   370      21.084  23.453  52.851  1.00 25.75
ATOM   3126  CZ3 TRP   370      22.965  21.994  52.518  1.00 25.56
ATOM   3127  CH2 TRP   370      22.434  23.272  52.563  1.00 25.71
ATOM   3128  N   LYS   371      20.009  16.118  53.137  1.00 33.52
ATOM   3129  CA  LYS   371      20.217  14.693  53.269  1.00 35.38
ATOM   3130  C   LYS   371      19.151  13.892  52.496  1.00 37.36
ATOM   3131  O   LYS   371      19.436  12.849  51.919  1.00 38.57
ATOM   3132  CB  LYS   371      20.220  14.379  54.763  1.00 34.85
ATOM   3133  CG  LYS   371      21.402  13.521  55.148  1.00 34.72
ATOM   3134  CD  LYS   371      21.014  12.703  56.366  1.00 34.64
ATOM   3135  CE  LYS   371      21.924  11.524  56.657  1.00 34.94
ATOM   3136  NZ  LYS   371      21.686  10.936  57.970  1.00 35.19
ATOM   3137  N   GLU   372      17.948  14.426  52.315  1.00 38.37
ATOM   3138  CA  GLU   372      16.894  13.740  51.594  1.00 38.94
ATOM   3139  C   GLU   372      17.112  13.847  50.073  1.00 38.60
ATOM   3140  O   GLU   372      16.404  13.167  49.308  1.00 39.16
ATOM   3141  CB  GLU   372      15.544  14.353  51.976  1.00 40.36
ATOM   3142  CG  GLU   372      15.389  14.742  53.440  1.00 42.85
ATOM   3143  CD  GLU   372      16.065  13.800  54.445  1.00 45.01
ATOM   3144  OE1 GLU   372      15.750  12.614  54.484  1.00 47.04
ATOM   3145  OE2 GLU   372      16.946  14.241  55.179  1.00 46.18
ATOM   3146  N   GLY   373      18.040  14.684  49.569  1.00 36.89
ATOM   3147  CA  GLY   373      18.331  14.748  48.142  1.00 35.38
ATOM   3148  C   GLY   373      17.280  15.474  47.350  1.00 34.14
ATOM   3149  O   GLY   373      16.652  16.384  47.866  1.00 32.97
ATOM   3150  N   PHE   374      17.060  15.078  46.095  1.00 34.19
ATOM   3151  CA  PHE   374      16.069  15.729  45.204  1.00 33.59
ATOM   3152  C   PHE   374      14.595  15.229  45.170  1.00 34.08
ATOM   3153  O   PHE   374      13.715  15.700  44.410  1.00 34.24
ATOM   3154  CB  PHE   374      16.602  15.676  43.812  1.00 31.81
ATOM   3155  CG  PHE   374      17.945  16.344  43.695  1.00 30.29
ATOM   3156  CD1 PHE   374      18.006  17.713  43.532  1.00 28.78
ATOM   3157  CD2 PHE   374      19.098  15.561  43.673  1.00 29.97
ATOM   3158  CE1 PHE   374      19.236  18.306  43.326  1.00 28.81
ATOM   3159  CE2 PHE   374      20.333  16.172  43.462  1.00 28.84
ATOM   3160  CZ  PHE   374      20.398  17.548  43.288  1.00 28.49
ATOM   3161  N   GLY   375      14.328  14.227  46.014  1.00 33.34
ATOM   3162  CA  GLY   375      12.998  13.681  46.161  1.00 33.01
ATOM   3163  C   GLY   375      11.975  14.747  46.562  1.00 32.57
ATOM   3164  O   GLY   375      10.981  14.851  45.865  1.00 33.78
ATOM   3165  N   PRO   376      12.063  15.527  47.638  1.00 31.65
ATOM   3166  CA  PRO   376      11.037  16.476  48.003  1.00 30.83
ATOM   3167  C   PRO   376      10.914  17.641  47.029  1.00 31.00
ATOM   3168  O   PRO   376      11.918  18.236  46.596  1.00 32.17
ATOM   3169  CB  PRO   376      11.434  16.849  49.373  1.00 30.86
ATOM   3170  CG  PRO   376      12.122  15.591  49.838  1.00 30.83
ATOM   3171  CD  PRO   376      13.037  15.369  48.697  1.00 31.05
ATOM   3172  N   ARG   377       9.668  17.986  46.648  1.00 30.24
ATOM   3173  CA  ARG   377       9.402  19.066  45.684  1.00 29.19
ATOM   3174  C   ARG   377       8.696  20.240  46.335  1.00 27.01
ATOM   3175  O   ARG   377       7.483  20.225  46.510  1.00 26.91
ATOM   3176  CB  ARG   377       8.529  18.571  44.539  1.00 30.55
ATOM   3177  CG  ARG   377       8.792  17.146  44.129  1.00 31.37
ATOM   3178  CD  ARG   377      10.223  16.929  43.715  1.00 31.86
ATOM   3179  NE  ARG   377      10.519  17.475  42.419  1.00 32.88
ATOM   3180  CZ  ARG   377      11.266  16.776  41.574  1.00 33.16
ATOM   3181  NH1 ARG   377      11.727  15.565  41.929  1.00 33.24
ATOM   3182  NH2 ARG   377      11.592  17.333  40.398  1.00 33.23
ATOM   3183  N   PHE   378       9.497  21.220  46.740  1.00 24.58
ATOM   3184  CA  PHE   378       9.022  22.382  47.461  1.00 23.21
ATOM   3185  C   PHE   378       8.753  23.570  46.564  1.00 24.72
ATOM   3186  O   PHE   378       8.294  24.626  47.005  1.00 26.30
ATOM   3187  CB  PHE   378      10.030  22.881  48.476  1.00 21.01
ATOM   3188  CG  PHE   378      10.098  22.147  49.785  1.00 19.78
ATOM   3189  CD1 PHE   378      10.816  20.966  49.895  1.00 19.80
ATOM   3190  CD2 PHE   378       9.409  22.645  50.872  1.00 20.08
ATOM   3191  CE1 PHE   378      10.845  20.264  51.097  1.00 20.07
ATOM   3192  CE2 PHE   378       9.426  21.949  52.080  1.00 20.63
ATOM   3193  CZ  PHE   378      10.144  20.754  52.196  1.00 20.45
ATOM   3194  N   GLY   379       9.022  23.439  45.274  1.00 24.89
ATOM   3195  CA  GLY   379       9.088  24.614  44.465  1.00 23.89
ATOM   3196  C   GLY   379       7.788  24.870  43.813  1.00 24.45
ATOM   3197  O   GLY   379       6.962  24.011  43.556  1.00 23.80
ATOM   3198  N   LEU   380       7.658  26.143  43.591  1.00 25.73
ATOM   3199  CA  LEU   380       6.539  26.628  42.850  1.00 27.42
ATOM   3200  C   LEU   380       6.812  26.350  41.343  1.00 29.25
ATOM   3201  O   LEU   380       5.912  26.222  40.511  1.00 28.88
ATOM   3202  CB  LEU   380       6.450  28.091  43.111  1.00 26.26
ATOM   3203  CG  LEU   380       6.318  28.785  44.404  1.00 24.94
ATOM   3204  CD1 LEU   380       7.085  30.065  44.156  1.00 25.30
ATOM   3205  CD2 LEU   380       4.907  29.091  44.838  1.00 23.81
ATOM   3206  N   VAL   381       8.091  26.356  40.974  1.00 30.83
ATOM   3207  CA  VAL   381       8.577  26.189  39.632  1.00 32.51
ATOM   3208  C   VAL   381       9.193  24.819  39.683  1.00 34.56
ATOM   3209  O   VAL   381       9.945  24.541  40.614  1.00 36.42
ATOM   3210  CB  VAL   381       9.634  27.258  39.325  1.00 31.85
ATOM   3211  CG1 VAL   381      10.331  26.968  38.002  1.00 32.12
ATOM   3212  CG2 VAL   381       8.951  28.627  39.273  1.00 31.48
ATOM   3213  N   GLU   382       8.871  23.929  38.754  1.00 36.94
ATOM   3214  CA  GLU   382       9.448  22.609  38.715  1.00 38.87
ATOM   3215  C   GLU   382      10.770  22.670  37.963  1.00 39.45
ATOM   3216  O   GLU   382      10.882  23.443  36.994  1.00 39.59
ATOM   3217  CB  GLU   382       8.480  21.705  38.028  1.00 40.58
ATOM   3218  CG  GLU   382       9.065  20.341  37.775  1.00 43.48
ATOM   3219  CD  GLU   382       7.978  19.380  37.363  1.00 46.36
ATOM   3220  OE1 GLU   382       7.555  19.466  36.196  1.00 47.77
ATOM   3221  OE2 GLU   382       7.556  18.574  38.215  1.00 47.50
ATOM   3222  N   VAL   383      11.779  21.908  38.427  1.00 39.99
ATOM   3223  CA  VAL   383      13.049  21.838  37.736  1.00 40.37
ATOM   3224  C   VAL   383      13.091  20.399  37.275  1.00 42.52
ATOM   3225  O   VAL   383      12.762  19.484  38.047  1.00 42.89
ATOM   3226  CB  VAL   383      14.265  22.099  38.643  1.00 38.62
ATOM   3227  CG1 VAL   383      15.519  22.024  37.799  1.00 38.36
ATOM   3228  CG2 VAL   383      14.236  23.475  39.220  1.00 37.24
ATOM   3229  N   ASP   384      13.397  20.220  35.985  1.00 44.78
ATOM   3230  CA  ASP   384      13.603  18.905  35.371  1.00 46.92
ATOM   3231  C   ASP   384      15.096  18.702  35.645  1.00 48.04
ATOM   3232  O   ASP   384      15.904  19.467  35.089  1.00 48.85
ATOM   3233  CB  ASP   384      13.294  18.975  33.837  1.00 47.41
ATOM   3234  CG  ASP   384      13.629  17.749  32.970  1.00 47.62
ATOM   3235  OD1 ASP   384      12.742  17.215  32.320  1.00 47.70
ATOM   3236  OD2 ASP   384      14.775  17.318  32.912  1.00 47.85
ATOM   3237  N   TYR   385      15.548  17.712  36.422  1.00 48.50
ATOM   3238  CA  TYR   385      16.961  17.653  36.745  1.00 49.11
ATOM   3239  C   TYR   385      17.863  17.178  35.630  1.00 49.89
ATOM   3240  O   TYR   385      19.075  17.363  35.689  1.00 50.78
ATOM   3241  CB  TYR   385      17.129  16.791  37.981  1.00 49.14
ATOM   3242  CG  TYR   385      16.713  17.607  39.212  1.00 49.67
ATOM   3243  CD1 TYR   385      17.478  18.727  39.564  1.00 49.41
ATOM   3244  CE1 TYR   385      17.107  19.523  40.633  1.00 49.43
ATOM   3245  CD2 TYR   385      15.568  17.281  39.952  1.00 49.02
ATOM   3246  CE2 TYR   385      15.198  18.074  41.030  1.00 48.98
ATOM   3247  CZ  TYR   385      15.975  19.182  41.349  1.00 49.58
ATOM   3248  OH  TYR   385      15.662  19.969  42.422  1.00 50.95
ATOM   3249  N   GLN   386      17.312  16.625  34.554  1.00 49.68
ATOM   3250  CA  GLN   386      18.158  16.171  33.487  1.00 49.83
ATOM   3251  C   GLN   386      18.348  17.227  32.416  1.00 49.56
ATOM   3252  O   GLN   386      19.230  17.092  31.582  1.00 49.66
ATOM   3253  CB  GLN   386      17.559  14.890  32.929  1.00 50.63
ATOM   3254  CG  GLN   386      17.624  13.697  33.919  1.00 52.18
ATOM   3255  CD  GLN   386      16.736  13.719  35.189  1.00 53.56
ATOM   3256  OE1 GLN   386      15.964  14.648  35.509  1.00 54.18
ATOM   3257  NE2 GLN   386      16.789  12.660  35.995  1.00 53.98
ATOM   3258  N   THR   387      17.576  18.306  32.401  1.00 49.56
ATOM   3259  CA  THR   387      17.683  19.352  31.381  1.00 49.61
ATOM   3260  C   THR   387      17.853  20.711  32.024  1.00 49.06
ATOM   3261  O   THR   387      18.185  21.676  31.347  1.00 48.78
ATOM   3262  CB  THR   387      16.420  19.511  30.508  1.00 50.24
ATOM   3263  OG1 THR   387      15.900  18.210  30.256  1.00 51.18
ATOM   3264  CG2 THR   387      16.701  20.256  29.202  1.00 50.24
ATOM   3265  N   PHE   388      17.555  20.785  33.327  1.00 48.68
ATOM   3266  CA  PHE   388      17.452  22.005  34.122  1.00 48.11
ATOM   3267  C   PHE   388      16.359  22.890  33.525  1.00 48.65
ATOM   3268  O   PHE   388      16.425  24.115  33.611  1.00 49.51
ATOM   3269  CB  PHE   388      18.843  22.736  34.197  1.00 47.19
ATOM   3270  CG  PHE   388      19.893  21.767  34.738  1.00 46.26
ATOM   3271  CD1 PHE   388      20.952  21.378  33.922  1.00 46.02
ATOM   3272  CD2 PHE   388      19.714  21.164  35.987  1.00 45.78
ATOM   3273  CE1 PHE   388      21.811  20.367  34.361  1.00 46.39
ATOM   3274  CE2 PHE   388      20.572  20.161  36.416  1.00 45.37
ATOM   3275  CZ  PHE   388      21.621  19.754  35.604  1.00 46.03
ATOM   3276  N   GLU   389      15.305  22.246  32.951  1.00 48.62
ATOM   3277  CA  GLU   389      14.113  22.909  32.412  1.00 48.13
ATOM   3278  C   GLU   389      13.283  23.394  33.599  1.00 46.53
ATOM   3279  O   GLU   389      13.007  22.601  34.507  1.00 46.28
ATOM   3280  CB  GLU   389      13.176  21.976  31.641  1.00 50.50
ATOM   3281  CG  GLU   389      13.588  21.355  30.297  1.00 53.10
ATOM   3282  CD  GLU   389      12.546  20.436  29.609  1.00 54.41
ATOM   3283  OE1 GLU   389      12.697  19.203  29.641  1.00 54.68
ATOM   3284  OE2 GLU   389      11.577  20.961  29.035  1.00 54.81
ATOM   3285  N   ARG   390      12.886  24.659  33.618  1.00 44.11
ATOM   3286  CA  ARG   390      12.070  25.216  34.692  1.00 42.52
ATOM   3287  C   ARG   390      10.654  25.349  34.162  1.00 41.17
ATOM   3288  O   ARG   390      10.427  25.826  33.044  1.00 41.16
ATOM   3289  CB  ARG   390      12.487  26.643  35.121  1.00 42.58
ATOM   3290  CG  ARG   390      13.624  26.885  36.106  1.00 41.23
ATOM   3291  CD  ARG   390      14.837  26.213  35.578  1.00 39.94
ATOM   3292  NE  ARG   390      15.997  26.871  36.104  1.00 38.30
ATOM   3293  CZ  ARG   390      16.941  26.190  36.727  1.00 36.85
ATOM   3294  NH1 ARG   390      16.854  24.859  36.868  1.00 35.38
ATOM   3295  NH2 ARG   390      17.935  26.909  37.234  1.00 35.67
ATOM   3296  N   ARG   391       9.641  24.996  34.916  1.00 39.14
ATOM   3297  CA  ARG   391       8.307  25.101  34.377  1.00 36.16
ATOM   3298  C   ARG   391       7.457  25.489  35.560  1.00 32.38
ATOM   3299  O   ARG   391       7.345  24.665  36.472  1.00 31.95
ATOM   3300  CB  ARG   391       7.844  23.773  33.858  1.00 39.05
ATOM   3301  CG  ARG   391       8.900  22.752  33.455  1.00 42.47
ATOM   3302  CD  ARG   391       8.247  21.369  33.414  1.00 45.20
ATOM   3303  NE  ARG   391       9.221  20.320  33.182  1.00 47.38
ATOM   3304  CZ  ARG   391       9.835  20.203  32.000  1.00 48.92
ATOM   3305  NH1 ARG   391       9.600  21.043  30.973  1.00 49.26
ATOM   3306  NH2 ARG   391      10.691  19.201  31.844  1.00 49.83
ATOM   3307  N   PRO   392       6.913  26.700  35.651  1.00 28.02
ATOM   3308  CA  PRO   392       6.011  27.093  36.716  1.00 26.41
ATOM   3309  C   PRO   392       4.771  26.215  36.881  1.00 26.79
ATOM   3310  O   PRO   392       4.115  25.859  35.918  1.00 28.33
ATOM   3311  CB  PRO   392       5.672  28.522  36.406  1.00 25.39
ATOM   3312  CG  PRO   392       6.847  29.038  35.654  1.00 26.27
ATOM   3313  CD  PRO   392       7.337  27.831  34.852  1.00 26.90
ATOM   3314  N   ARG   393       4.430  25.777  38.083  1.00 25.72
ATOM   3315  CA  ARG   393       3.254  25.027  38.400  1.00 23.83
ATOM   3316  C   ARG   393       2.131  26.020  38.502  1.00 23.46
ATOM   3317  O   ARG   393       2.351  27.214  38.485  1.00 24.07
ATOM   3318  CB  ARG   393       3.487  24.333  39.718  1.00 25.02
ATOM   3319  CG  ARG   393       4.596  23.297  39.575  1.00 26.05
ATOM   3320  CD  ARG   393       4.894  22.520  40.841  1.00 26.93
ATOM   3321  NE  ARG   393       5.643  21.286  40.590  1.00 27.84
ATOM   3322  CZ  ARG   393       6.747  20.960  41.285  1.00 27.53
ATOM   3323  NH1 ARG   393       7.193  21.777  42.229  1.00 27.31
ATOM   3324  NH2 ARG   393       7.401  19.815  41.043  1.00 26.55
ATOM   3325  N   LYS   394       0.871  25.648  38.607  1.00 24.40
ATOM   3326  CA  LYS   394      -0.220  26.592  38.757  1.00 24.49
ATOM   3327  C   LYS   394       0.071  27.478  39.971  1.00 24.87
ATOM   3328  O   LYS   394      -0.177  28.683  39.844  1.00 26.36
ATOM   3329  CB  LYS   394      -1.560  25.813  38.937  1.00 25.44
ATOM   3330  CG  LYS   394      -2.828  26.630  39.275  1.00 27.41
ATOM   3331  CD  LYS   394      -4.062  25.734  39.422  1.00 28.31
ATOM   3332  CE  LYS   394      -5.207  26.564  40.033  1.00 29.13
ATOM   3333  NZ  LYS   394      -6.375  25.761  40.419  1.00 30.13
ATOM   3334  N   SER   395       0.642  26.988  41.107  1.00 23.80
ATOM   3335  CA  SER   395       0.950  27.792  42.302  1.00 21.44
ATOM   3336  C   SER   395       1.766  29.002  41.982  1.00 20.63
ATOM   3337  O   SER   395       1.433  30.078  42.459  1.00 19.89
ATOM   3338  CB  SER   395       1.719  26.974  43.373  1.00 22.36
ATOM   3339  OG  SER   395       2.512  25.867  42.929  1.00 20.74
ATOM   3340  N   ALA   396       2.782  28.822  41.135  1.00 20.77
ATOM   3341  CA  ALA   396       3.661  29.876  40.648  1.00 21.65
ATOM   3342  C   ALA   396       2.879  31.056  40.115  1.00 23.59
ATOM   3343  O   ALA   396       3.096  32.207  40.514  1.00 24.10
ATOM   3344  CB  ALA   396       4.505  29.331  39.562  1.00 20.62
ATOM   3345  N   TYR   397       1.897  30.751  39.251  1.00 25.58
ATOM   3346  CA  TYR   397       0.933  31.759  38.781  1.00 25.24
ATOM   3347  C   TYR   397      -0.053  32.240  39.872  1.00 24.38
ATOM   3348  O   TYR   397      -0.136  33.471  40.030  1.00 25.89
ATOM   3349  CB  TYR   397       0.155  31.202  37.604  1.00 25.90
ATOM   3350  CG  TYR   397       1.081  30.898  36.451  1.00 27.18
ATOM   3351  CD1 TYR   397       1.506  29.584  36.209  1.00 27.72
ATOM   3352  CE1 TYR   397       2.381  29.332  35.140  1.00 28.09
ATOM   3353  CD2 TYR   397       1.524  31.942  35.631  1.00 28.26
ATOM   3354  CE2 TYR   397       2.405  31.696  34.555  1.00 28.12
ATOM   3355  CZ  TYR   397       2.830  30.389  34.319  1.00 28.44
ATOM   3356  OH  TYR   397       3.726  30.145  33.285  1.00 29.35
ATOM   3357  N   VAL   398      -0.751  31.415  40.685  1.00 22.00
ATOM   3358  CA  VAL   398      -1.673  31.871  41.725  1.00 21.29
ATOM   3359  C   VAL   398      -0.958  32.852  42.594  1.00 22.64
ATOM   3360  O   VAL   398      -1.396  33.992  42.718  1.00 22.80
ATOM   3361  CB  VAL   398      -2.198  30.728  42.675  1.00 22.12
ATOM   3362  CG1 VAL   398      -3.060  31.318  43.801  1.00 20.84
ATOM   3363  CG2 VAL   398      -3.090  29.708  41.904  1.00 21.79
ATOM   3364  N   TYR   399       0.195  32.395  43.112  1.00 24.95
ATOM   3365  CA  TYR   399       1.057  33.119  44.027  1.00 25.60
ATOM   3366  C   TYR   399       1.571  34.408  43.417  1.00 26.15
ATOM   3367  O   TYR   399       1.562  35.481  44.061  1.00 26.45
ATOM   3368  CB  TYR   399       2.223  32.224  44.442  1.00 26.89
ATOM   3369  CG  TYR   399       3.084  32.861  45.529  1.00 27.95
ATOM   3370  CD1 TYR   399       2.518  33.303  46.723  1.00 28.51
ATOM   3371  CE1 TYR   399       3.305  33.982  47.654  1.00 29.38
ATOM   3372  CD2 TYR   399       4.437  33.088  45.286  1.00 28.78
ATOM   3373  CE2 TYR   399       5.218  33.776  46.208  1.00 28.56
ATOM   3374  CZ  TYR   399       4.647  34.222  47.379  1.00 29.05
ATOM   3375  OH  TYR   399       5.399  34.991  48.241  1.00 29.99
ATOM   3376  N   GLY   400       1.977  34.324  42.147  1.00 26.71
ATOM   3377  CA  GLY   400       2.424  35.511  41.407  1.00 26.29
ATOM   3378  C   GLY   400       1.367  36.600  41.361  1.00 25.79
ATOM   3379  O   GLY   400       1.714  37.777  41.387  1.00 24.79
ATOM   3380  N   GLU   401       0.075  36.231  41.322  1.00 26.61
ATOM   3381  CA  GLU   401      -0.984  37.220  41.342  1.00 27.93
ATOM   3382  C   GLU   401      -1.111  37.810  42.705  1.00 27.07
ATOM   3383  O   GLU   401      -1.264  39.012  42.791  1.00 27.04
ATOM   3384  CB  GLU   401      -2.375  36.654  40.983  1.00 31.43
ATOM   3385  CG  GLU   401      -3.242  37.283  39.827  1.00 33.77
ATOM   3386  CD  GLU   401      -3.433  38.816  39.744  1.00 35.13
ATOM   3387  OE1 GLU   401      -4.420  39.307  40.329  1.00 35.32
ATOM   3388  OE2 GLU   401      -2.606  39.489  39.075  1.00 34.97
ATOM   3389  N   ILE   402      -1.113  37.044  43.786  1.00 28.13
ATOM   3390  CA  ILE   402      -1.116  37.557  45.171  1.00 27.99
ATOM   3391  C   ILE   402       0.049  38.507  45.397  1.00 29.39
ATOM   3392  O   ILE   402      -0.141  39.554  46.006  1.00 29.35
ATOM   3393  CB  ILE   402      -1.026  36.392  46.202  1.00 26.51
ATOM   3394  CG2 ILE   402      -0.847  36.948  47.594  1.00 26.71
ATOM   3395  CG1 ILE   402      -2.334  35.626  46.255  1.00 25.78
ATOM   3396  CD1 ILE   402      -2.394  34.103  46.319  1.00 24.88
ATOM   3397  N   ALA   403       1.249  38.183  44.882  1.00 31.15
ATOM   3398  CA  ALA   403       2.422  39.033  45.034  1.00 32.45
ATOM   3399  C   ALA   403       2.222  40.345  44.308  1.00 33.90
ATOM   3400  O   ALA   403       2.442  41.420  44.864  1.00 35.84
ATOM   3401  CB  ALA   403       3.651  38.330  44.474  1.00 31.98
ATOM   3402  N   ARG   404       1.687  40.254  43.083  1.00 35.53
ATOM   3403  CA  ARG   404       1.298  41.383  42.204  1.00 35.70
ATOM   3404  C   ARG   404       0.155  42.299  42.648  1.00 34.25
ATOM   3405  O   ARG   404       0.223  43.513  42.655  1.00 33.30
ATOM   3406  CB  ARG   404       0.999  40.738  40.869  1.00 37.13
ATOM   3407  CG  ARG   404       0.521  41.583  39.720  1.00 39.06
ATOM   3408  CD  ARG   404       0.539  40.651  38.531  1.00 39.67
ATOM   3409  NE  ARG   404       1.894  40.549  38.012  1.00 40.70
ATOM   3410  CZ  ARG   404       2.412  39.377  37.646  1.00 41.56
ATOM   3411  NH1 ARG   404       1.717  38.236  37.765  1.00 41.05
ATOM   3412  NH2 ARG   404       3.607  39.387  37.034  1.00 41.91
ATOM   3413  N   SER   405      -0.940  41.715  43.043  1.00 34.00
ATOM   3414  CA  SER   405      -2.088  42.466  43.446  1.00 35.00
ATOM   3415  C   SER   405      -2.019  43.032  44.859  1.00 36.63
ATOM   3416  O   SER   405      -2.717  44.004  45.216  1.00 37.70
ATOM   3417  CB  SER   405      -3.291  41.550  43.306  1.00 34.15
ATOM   3418  OG  SER   405      -3.221  40.329  44.014  1.00 33.08
ATOM   3419  N   LYS   406      -1.166  42.337  45.647  1.00 37.17
ATOM   3420  CA  LYS   406      -1.063  42.435  47.093  1.00 36.54
ATOM   3421  C   LYS   406      -2.400  42.011  47.687  1.00 36.75
ATOM   3422  O   LYS   406      -2.764  42.464  48.779  1.00 36.02
ATOM   3423  CB  LYS   406      -0.744  43.854  47.605  1.00 36.72
ATOM   3424  CG  LYS   406       0.571  44.387  47.129  1.00 36.89
ATOM   3425  CD  LYS   406       1.712  43.432  47.390  1.00 37.10
ATOM   3426  CE  LYS   406       2.977  44.127  46.914  1.00 38.18
ATOM   3427  NZ  LYS   406       2.906  44.322  45.471  1.00 39.01
ATOM   3428  N   GLU   407      -3.170  41.124  47.050  1.00 36.65
ATOM   3429  CA  GLU   407      -4.368  40.691  47.689  1.00 37.87
ATOM   3430  C   GLU   407      -4.711  39.303  47.277  1.00 37.83
ATOM   3431  O   GLU   407      -4.372  38.843  46.192  1.00 38.44
ATOM   3432  CB  GLU   407      -5.518  41.597  47.350  1.00 39.56
ATOM   3433  CG  GLU   407      -5.856  41.581  45.879  1.00 41.89
ATOM   3434  CD  GLU   407      -7.022  42.463  45.503  1.00 42.93
ATOM   3435  OE1 GLU   407      -7.133  43.539  46.099  1.00 43.86
ATOM   3436  OE2 GLU   407      -7.787  42.061  44.614  1.00 43.29
ATOM   3437  N   ILE   408      -5.351  38.596  48.188  1.00 38.17
ATOM   3438  CA  ILE   408      -5.819  37.260  47.933  1.00 37.92
ATOM   3439  C   ILE   408      -7.288  37.626  47.737  1.00 40.55
ATOM   3440  O   ILE   408      -7.999  38.151  48.625  1.00 40.36
ATOM   3441  CB  ILE   408      -5.637  36.348  49.153  1.00 36.31
ATOM   3442  CG2 ILE   408      -6.227  35.007  48.778  1.00 35.84
ATOM   3443  CG1 ILE   408      -4.175  36.193  49.558  1.00 34.48
ATOM   3444  CD1 ILE   408      -4.068  35.415  50.847  1.00 33.13
ATOM   3445  N   LYS   409      -7.728  37.428  46.493  1.00 42.35
ATOM   3446  CA  LYS   409      -9.098  37.745  46.209  1.00 43.85
ATOM   3447  C   LYS   409     -10.075  36.596  46.286  1.00 43.53
ATOM   3448  O   LYS   409      -9.815  35.389  46.176  1.00 43.35
ATOM   3449  CB  LYS   409      -9.173  38.411  44.835  1.00 45.12
ATOM   3450  CG  LYS   409      -8.941  37.523  43.639  1.00 46.43
ATOM   3451  CD  LYS   409      -8.218  38.399  42.633  1.00 48.23
ATOM   3452  CE  LYS   409      -8.941  39.688  42.202  1.00 49.37
ATOM   3453  NZ  LYS   409      -8.020  40.537  41.443  1.00 50.82
ATOM   3454  N   ASP   410     -11.225  37.170  46.575  1.00 44.06
ATOM   3455  CA  ASP   410     -12.513  36.540  46.523  1.00 44.82
ATOM   3456  C   ASP   410     -12.524  35.080  46.092  1.00 44.24
ATOM   3457  O   ASP   410     -12.623  34.226  46.976  1.00 43.98
ATOM   3458  CB  ASP   410     -13.427  37.444  45.576  1.00 46.96
ATOM   3459  CG  ASP   410     -13.067  37.791  44.087  1.00 47.20
ATOM   3460  OD1 ASP   410     -13.334  36.978  43.182  1.00 46.47
ATOM   3461  OD2 ASP   410     -12.560  38.900  43.844  1.00 47.70
ATOM   3462  N   GLU   411     -12.242  34.847  44.781  1.00 43.31
ATOM   3463  CA  GLU   411     -12.363  33.564  44.118  1.00 42.14
ATOM   3464  C   GLU   411     -11.479  32.510  44.765  1.00 41.82
ATOM   3465  O   GLU   411     -11.894  31.386  45.110  1.00 40.70
ATOM   3466  CB  GLU   411     -12.034  33.738  42.601  1.00 42.49
ATOM   3467  CG  GLU   411     -10.619  34.148  42.122  1.00 43.07
ATOM   3468  CD  GLU   411      -9.799  33.252  41.149  1.00 43.50
ATOM   3469  OE1 GLU   411      -9.800  32.007  41.252  1.00 43.42
ATOM   3470  OE2 GLU   411      -9.092  33.820  40.303  1.00 43.22
ATOM   3471  N   LEU   412     -10.265  32.972  45.062  1.00 41.40
ATOM   3472  CA  LEU   412      -9.272  32.073  45.597  1.00 41.28
ATOM   3473  C   LEU   412      -9.552  31.720  47.021  1.00 41.57
ATOM   3474  O   LEU   412      -9.479  30.558  47.440  1.00 41.43
ATOM   3475  CB  LEU   412      -7.942  32.706  45.506  1.00 40.48
ATOM   3476  CG  LEU   412      -7.468  32.802  44.090  1.00 39.90
ATOM   3477  CD1 LEU   412      -6.365  33.861  44.055  1.00 39.67
ATOM   3478  CD2 LEU   412      -7.143  31.396  43.564  1.00 38.71
ATOM   3479  N   LEU   413      -9.930  32.786  47.715  1.00 42.15
ATOM   3480  CA  LEU   413     -10.201  32.696  49.131  1.00 42.64
ATOM   3481  C   LEU   413     -11.335  31.700  49.359  1.00 43.37
ATOM   3482  O   LEU   413     -11.138  30.773  50.134  1.00 43.83
ATOM   3483  CB  LEU   413     -10.479  34.143  49.587  1.00 41.69
ATOM   3484  CG  LEU   413      -9.879  34.683  50.890  1.00 41.20
ATOM   3485  CD1 LEU   413      -8.502  34.106  51.157  1.00 40.67
ATOM   3486  CD2 LEU   413      -9.791  36.194  50.772  1.00 40.64
ATOM   3487  N   LYS   414     -12.444  31.745  48.621  1.00 44.61
ATOM   3488  CA  LYS   414     -13.530  30.780  48.747  1.00 45.31
ATOM   3489  C   LYS   414     -13.101  29.373  48.312  1.00 44.48
ATOM   3490  O   LYS   414     -13.564  28.377  48.870  1.00 43.71
ATOM   3491  CB  LYS   414     -14.709  31.282  47.893  1.00 46.94
ATOM   3492  CG  LYS   414     -16.100  31.001  48.479  1.00 49.45
ATOM   3493  CD  LYS   414     -16.612  29.543  48.313  1.00 51.40
ATOM   3494  CE  LYS   414     -17.792  29.080  49.214  1.00 51.84
ATOM   3495  NZ  LYS   414     -17.893  27.614  49.151  1.00 52.66
ATOM   3496  N   ARG   415     -12.215  29.235  47.328  1.00 44.14
ATOM   3497  CA  ARG   415     -11.788  27.919  46.875  1.00 44.62
ATOM   3498  C   ARG   415     -10.816  27.056  47.700  1.00 44.98
ATOM   3499  O   ARG   415     -10.778  25.806  47.691  1.00 44.72
ATOM   3500  CB  ARG   415     -11.190  28.073  45.520  1.00 45.04
ATOM   3501  CG  ARG   415     -11.796  26.957  44.697  1.00 46.66
ATOM   3502  CD  ARG   415     -11.229  26.888  43.299  1.00 47.93
ATOM   3503  NE  ARG   415     -11.184  28.198  42.663  1.00 48.69
ATOM   3504  CZ  ARG   415     -12.250  28.870  42.245  1.00 48.71
ATOM   3505  NH1 ARG   415     -13.507  28.452  42.343  1.00 48.66
ATOM   3506  NH2 ARG   415     -11.985  30.035  41.708  1.00 49.95
ATOM   3507  N   TYR   416      -9.929  27.833  48.317  1.00 44.84
ATOM   3508  CA  TYR   416      -8.768  27.358  49.031  1.00 43.52
ATOM   3509  C   TYR   416      -8.695  27.659  50.493  1.00 43.83
ATOM   3510  O   TYR   416      -8.136  26.838  51.206  1.00 43.67
ATOM   3511  CB  TYR   416      -7.546  27.955  48.407  1.00 42.73
ATOM   3512  CG  TYR   416      -7.365  27.421  47.027  1.00 41.46
ATOM   3513  CD1 TYR   416      -7.429  28.282  45.942  1.00 41.25
ATOM   3514  CE1 TYR   416      -7.266  27.753  44.657  1.00 40.67
ATOM   3515  CD2 TYR   416      -7.151  26.048  46.872  1.00 41.42
ATOM   3516  CE2 TYR   416      -6.992  25.515  45.595  1.00 40.79
ATOM   3517  CZ  TYR   416      -7.057  26.377  44.517  1.00 40.31
ATOM   3518  OH  TYR   416      -6.912  25.844  43.285  1.00 39.59
ATOM   3519  N   GLY   417      -9.109  28.885  50.840  1.00 43.71
ATOM   3520  CA  GLY   417      -9.014  29.436  52.171  1.00 45.37
ATOM   3521  C   GLY   417      -9.841  28.754  53.262  1.00 46.68
ATOM   3522  O   GLY   417     -10.503  27.748  53.028  1.00 46.37
ATOM   3523  N   LEU   418      -9.814  29.300  54.485  1.00 48.50
ATOM   3524  CA  LEU   418     -10.506  28.685  55.599  1.00 51.16
ATOM   3525  C   LEU   418     -11.704  29.570  55.897  1.00 54.54
ATOM   3526  O   LEU   418     -11.712  30.768  55.633  1.00 54.29
ATOM   3527  CB  LEU   418      -9.666  28.614  56.873  1.00 49.97
ATOM   3528  CG  LEU   418      -8.472  27.668  56.942  1.00 49.58
ATOM   3529  CD1 LEU   418      -7.435  28.215  57.893  1.00 48.79
ATOM   3530  CD2 LEU   418      -8.924  26.314  57.377  1.00 48.31
ATOM   3531  N   PRO   419     -12.791  28.979  56.375  1.00 57.98
ATOM   3532  CA  PRO   419     -13.930  29.724  56.893  1.00 60.93
ATOM   3533  C   PRO   419     -13.723  30.543  58.165  1.00 64.10
ATOM   3534  O   PRO   419     -14.228  31.655  58.328  1.00 65.01
ATOM   3535  CB  PRO   419     -14.981  28.653  57.049  1.00 60.46
ATOM   3536  CG  PRO   419     -14.176  27.373  57.196  1.00 59.70
ATOM   3537  CD  PRO   419     -13.126  27.571  56.145  1.00 58.43
ATOM   3538  N   GLU   420     -13.042  29.898  59.111  1.00 67.44
ATOM   3539  CA  GLU   420     -12.819  30.394  60.464  1.00 70.73
ATOM   3540  C   GLU   420     -12.337  31.828  60.739  1.00 72.57
ATOM   3541  O   GLU   420     -11.188  32.229  60.496  1.00 72.95
ATOM   3542  CB  GLU   420     -11.879  29.391  61.141  1.00 71.30
ATOM   3543  CG  GLU   420     -10.629  29.059  60.338  1.00 72.48
ATOM   3544  CD  GLU   420     -10.287  27.575  60.354  1.00 73.70
ATOM   3545  OE1 GLU   420      -9.119  27.250  60.606  1.00 74.25
ATOM   3546  OE2 GLU   420     -11.173  26.748  60.097  1.00 74.27
ATOM   3547  N   LEU   421     -13.291  32.516  61.417  1.00 74.45
ATOM   3548  CA  LEU   421     -13.214  33.940  61.790  1.00 76.12
ATOM   3549  C   LEU   421     -12.879  34.743  60.540  1.00 77.13
ATOM   3550  O   LEU   421     -12.034  35.645  60.477  1.00 77.02
ATOM   3551  CB  LEU   421     -12.148  34.140  62.921  1.00 76.34
ATOM   3552  CG  LEU   421     -11.482  35.463  63.414  1.00 76.33
ATOM   3553  CD1 LEU   421     -12.459  36.646  63.543  1.00 76.15
ATOM   3554  CD2 LEU   421     -10.827  35.119  64.747  1.00 76.19
ATOM   3555  N   GLN   422     -13.729  34.389  59.568  1.00 78.58
ATOM   3556  CA  GLN   422     -13.724  34.880  58.206  1.00 80.07
ATOM   3557  C   GLN   422     -12.321  34.767  57.596  1.00 80.41
ATOM   3558  O   GLN   422     -11.974  33.649  57.241  1.00 80.03
ATOM   3559  CB  GLN   422     -14.329  36.380  58.129  1.00 80.99
ATOM   3560  CG  GLN   422     -14.018  37.535  59.151  1.00 82.17
ATOM   3561  CD  GLN   422     -14.625  38.942  58.966  1.00 82.61
ATOM   3562  OE1 GLN   422     -15.439  39.430  59.754  1.00 82.52
ATOM   3563  NE2 GLN   422     -14.214  39.708  57.964  1.00 82.94
ATOM   3564  N   LEU   423     -11.538  35.833  57.826  1.00 81.10
ATOM   3565  CA  LEU   423     -10.336  36.246  57.126  1.00 81.46
ATOM   3566  C   LEU   423      -9.863  35.459  55.900  1.00 82.09
ATOM   3567  O   LEU   423     -10.528  35.623  54.868  1.00 82.84
ATOM   3568  CB  LEU   423      -9.207  36.392  58.191  1.00 80.97
ATOM   3569  CG  LEU   423      -8.205  37.538  57.815  1.00 80.70
ATOM   3570  CD1 LEU   423      -7.977  38.526  58.962  1.00 80.40
ATOM   3571  CD2 LEU   423      -6.918  36.893  57.376  1.00 79.98
ATOM   3572  OXT LEU   423      -8.831  34.802  55.912  1.00 82.47
TER    3573      LEU   423
【図面の簡単な説明】
【００４１】
【図１】β−グリコシダーゼの結晶を示す写真。
【図２】β−グリコシダーゼのＸ線回折像の一部を示す写真。
【図３】β−グリコシダーゼの三次元構造を示す写真。
【図１】
2005124450.tif 000002
【図２】
2005124450.tif 000003
【図３】
2005124450.tif 000004
【配列表】
2005124450000001.app