【手続補正書】
【提出日】平成23年10月3日(2011.10.3)
【手続補正１】
【補正対象書類名】明細書
【補正対象項目名】００７１
【補正方法】変更
【補正の内容】
【００７１】
配列表
SEQUENCE LISTING
<110>  AS Bergen Teknologioverforing AS
<120>  Novel reinoid inducible factor, and uses thereof
<130>  P11828NO01
<160>  37    
<170>  PatentIn version 3.5
<210>  1
<211>  2778
<212>  DNA
<213>  Homo sapiens
<400>  1
gttttgccgg cagcccccgg gcagcgttca tagctcctgc ccgggcgggc gcgcggcggc       60
ggcggcagag gcggctgagc ctgagcgggg atgtagaggc ggcggcagca gaggcggcac      120
tggcggcaag agcagacgcc cgagccgagc gagaagagcg gcagagcctt atcccctgaa      180
gccgggcccc gcgtcccagc cctgcccagc ccgcgcccag ccatgcgcgc cgcctgctga      240
gtccgggcgc cgcacgctga gccctccgcc cgcgagccgc gctcagctcg ggggtgatta      300
gttgcttttt gttgtttttt aatttgggcc gcggggaggg ggaggagggg caggtgctgc      360
aggctccccc ccctccccgc ctcgggccag ccgcggcggc gcgactcggg ctccggaccc      420
gggcactgct ggcggctgga gcggagcgca ccgcggcggt ggtgcccaga gcggagcgca      480
gctccctgcc ccgcccctcc ccctcggcct cgcggcgacg gcggcggtgg cggcttggac      540
gactcggaga gccggttcgg tgcgcggccg gggccggagt tcgctgcaag tcggcggaaa      600
gtttggctgc gcgggttccc ccgaagttca gagtgaagac atttccacct ggacacctga      660
ccatgtgcct gccctgagca gcgaggccca ccaggcatct ctgttgtggg cagcagggcc      720
aggtcctggt ctgtggaccc tcggcagttg gcaggctccc tctgcagtgg ggtctgggcc      780
tcggccccac catgtcgagc ctcggcggtg gctcccagga tgccggcggc agtagcagca      840
gcagcaccaa tggcagcggt ggcagtggca gcagtggccc aaaggcagga gcagcagaca      900
agagtgcagt ggtggctgcc gccgcaccag cctcagtggc agatgacaca ccaccccccg      960
agcgtcggaa caagagcggt atcatcagtg agcccctcaa caagagcctg cgccgctccc     1020
gcccgctctc ccactactct tcttttggca gcagtggtgg tagtggcggt ggcagcatga     1080
tgggcggaga gtctgctgac aaggccactg cggctgcagc cgctgcctcc ctgttggcca     1140
atgggcatga cctggcggcg gccatggcgg tggacaaaag caaccctacc tcaaagcaca     1200
aaagtggtgc tgtggccagc ctgctgagca aggcagagcg ggccacggag ctggcagccg     1260
agggacagct gacgctgcag cagtttgcgc agtccacaga gatgctgaag cgcgtggtgc     1320
aggagcatct cccgctgatg agcgaggcgg gtgctggcct gcctgacatg gaggctgtgg     1380
caggtgccga agccctcaat ggccagtccg acttccccta cctgggcgct ttccccatca     1440
acccaggcct cttcattatg accccggcag gtgtgttcct ggccgagagc gcgctgcaca     1500
tggcgggcct ggctgagtac cccatgcagg gagagctggc ctctgccatc agctccggca     1560
agaagaagcg gaaacgctgc ggcatgtgcg cgccctgccg gcggcgcatc aactgcgagc     1620
agtgcagcag ttgtaggaat cgaaagactg gccatcagat ttgcaaattc agaaaatgtg     1680
aggaactcaa aaagaagcct tccgctgctc tggagaaggt gatgcttccg acgggagccg     1740
ccttccggtg gtttcagtga cggcggcgga acccaaagct gccctctccg tgcaatgtca     1800
ctgctcgtgt ggtctccagc aagggattcg ggcgaagaca aacggatgca cccgtcttta     1860
gaaccaaaaa tattctctca cagatttcat tcctgttttt atatatatat tttttgttgt     1920
cgttttaaca tctccacgtc cctagcataa aaagaaaaag aaaaaaattt aaactgcttt     1980
ttcggaagaa caacaacaaa aaagaggtaa agacgaatct ataaagtacc gagacttcct     2040
gggcaaagaa tggacaatca gtttccttcc tgtgtcgatg tcgatgttgt ctgtgcagga     2100
gatgcagttt ttgtgtagag aatgtaaatt ttctgtaacc ttttgaaatc tagttactaa     2160
taagcactac tgtaatttag cacagtttaa ctccaccctc atttaaactt cctttgattc     2220
tttccgacca tgaaatagtg catagtttgc ctggagaatc cactcacgtt cataaagaga     2280
atgttgatgg cgccgtgtag aagccgctct gtatccatcc acgcgtgcag agctgccagc     2340
agggagctca cagaagggga gggagcacca ggccagctga gctgcaccca cagtcccgag     2400
actgggatcc cccaccccaa cagtgatttt ggaaaaaaaa atgaaagttc tgttcgttta     2460
tccattgcga tctggggagc cccatctcga tatttccaat cctggctact tttcttagag     2520
aaaataagtc ctttttttct ggccttgcta atggcaacag aagaaagggc ttctttgcgt     2580
ggtcccctgc tggtgggggt gggtccccag ggggccccct gcggcctggg cccccctgcc     2640
cacggccagc ttcctgctga tgaacatgct gtttgtattg ttttaggaaa ccaggctgtt     2700
ttgtgaataa aacgaatgca tgtttgtgtc acgaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760
aaaaaaaaaa aaaaaaaa                                                   2778
<210>  2
<211>  969
<212>  DNA
<213>  Homo sapiens
<400>  2
atgtcgagcc tcggcggtgg ctcccaggat gccggcggca gtagcagcag cagcaccaat       60
ggcagcggtg gcagtggcag cagtggccca aaggcaggag cagcagacaa gagtgcagtg      120
gtggctgccg ccgcaccagc ctcagtggca gatgacacac caccccccga gcgtcggaac      180
aagagcggta tcatcagtga gcccctcaac aagagcctgc gccgctcccg cccgctctcc      240
cactactctt cttttggcag cagtggtggt agtggcggtg gcagcatgat gggcggagag      300
tctgctgaca aggccactgc ggctgcagcc gctgcctccc tgttggccaa tgggcatgac      360
ctggcggcgg ccatggcggt ggacaaaagc aaccctacct caaagcacaa aagtggtgct      420
gtggccagcc tgctgagcaa ggcagagcgg gccacggagc tggcagccga gggacagctg      480
acgctgcagc agtttgcgca gtccacagag atgctgaagc gcgtggtgca ggagcatctc      540
ccgctgatga gcgaggcggg tgctggcctg cctgacatgg aggctgtggc aggtgccgaa      600
gccctcaatg gccagtccga cttcccctac ctgggcgctt tccccatcaa cccaggcctc      660
ttcattatga ccccggcagg tgtgttcctg gccgagagcg cgctgcacat ggcgggcctg      720
gctgagtacc ccatgcaggg agagctggcc tctgccatca gctccggcaa gaagaagcgg      780
aaacgctgcg gcatgtgcgc gccctgccgg cggcgcatca actgcgagca gtgcagcagt      840
tgtaggaatc gaaagactgg ccatcagatt tgcaaattca gaaaatgtga ggaactcaaa      900
aagaagcctt ccgctgctct ggagaaggtg atgcttccga cgggagccgc cttccggtgg      960
tttcagtga                                                              969
<210>  3
<211>  322
<212>  PRT
<213>  Homo sapiens
<400>  3
Met Ser Ser Leu Gly Gly Gly Ser Gln Asp Ala Gly Gly Ser Ser Ser 
1               5                   10                  15      
Ser Ser Thr Asn Gly Ser Gly Gly Ser Gly Ser Ser Gly Pro Lys Ala 
20                  25                  30          
Gly Ala Ala Asp Lys Ser Ala Val Val Ala Ala Ala Ala Pro Ala Ser 
35                  40                  45              
Val Ala Asp Asp Thr Pro Pro Pro Glu Arg Arg Asn Lys Ser Gly Ile 
50                  55                  60                  
Ile Ser Glu Pro Leu Asn Lys Ser Leu Arg Arg Ser Arg Pro Leu Ser 
65                  70                  75                  80  
His Tyr Ser Ser Phe Gly Ser Ser Gly Gly Ser Gly Gly Gly Ser Met 
85                  90                  95      
Met Gly Gly Glu Ser Ala Asp Lys Ala Thr Ala Ala Ala Ala Ala Ala 
100                 105                 110         
Ser Leu Leu Ala Asn Gly His Asp Leu Ala Ala Ala Met Ala Val Asp 
115                 120                 125             
Lys Ser Asn Pro Thr Ser Lys His Lys Ser Gly Ala Val Ala Ser Leu 
130                 135                 140                 
Leu Ser Lys Ala Glu Arg Ala Thr Glu Leu Ala Ala Glu Gly Gln Leu 
145                 150                 155                 160 
Thr Leu Gln Gln Phe Ala Gln Ser Thr Glu Met Leu Lys Arg Val Val 
165                 170                 175     
Gln Glu His Leu Pro Leu Met Ser Glu Ala Gly Ala Gly Leu Pro Asp 
180                 185                 190         
Met Glu Ala Val Ala Gly Ala Glu Ala Leu Asn Gly Gln Ser Asp Phe 
195                 200                 205             
Pro Tyr Leu Gly Ala Phe Pro Ile Asn Pro Gly Leu Phe Ile Met Thr 
210                 215                 220                 
Pro Ala Gly Val Phe Leu Ala Glu Ser Ala Leu His Met Ala Gly Leu 
225                 230                 235                 240 
Ala Glu Tyr Pro Met Gln Gly Glu Leu Ala Ser Ala Ile Ser Ser Gly 
245                 250                 255     
Lys Lys Lys Arg Lys Arg Cys Gly Met Cys Ala Pro Cys Arg Arg Arg 
260                 265                 270         
Ile Asn Cys Glu Gln Cys Ser Ser Cys Arg Asn Arg Lys Thr Gly His 
275                 280                 285             
Gln Ile Cys Lys Phe Arg Lys Cys Glu Glu Leu Lys Lys Lys Pro Ser 
290                 295                 300                 
Ala Ala Leu Glu Lys Val Met Leu Pro Thr Gly Ala Ala Phe Arg Trp 
305                 310                 315                 320 
Phe Gln 
<210>  4
<211>  18
<212>  DNA
<213>  Homo sapiens
<400>  4
cgagttcatg aggtgagc                                                     18
<210>  5
<211>  5000
<212>  DNA
<213>  Homo sapiens
<400>  5
ccccaagcac tgtctgagca ccccattcct tggagtctga agggaagggc agagtagggg       60
gtggtagctg gggtcttggg gccccaggtc tgaagagaaa gaggctgggc cattttcgga      120
agtctcagtg cgggccattt ctgaccctgc actgccctcc aggaccagat ttgtagagag      180
gaggctgagc cccaccctgc ctcctccagc aggcctcccc cacaccacca caccctagcc      240
ttcaggcttt gggtcgggca gggcactttc agggcaggct ggcttctcct gcccagggca      300
cccctcctcc aggtgcaggg ctccagattg ggacactgtg cctctgcctc ccctaaggcc      360
ccattcagtt acctccccac ctctcagcaa tgctctccct ccctcttcct gaagtgtggc      420
agggaggctg gagccacagc tttggcctct gggagcactc agtcccactc ccataggaca      480
gagttgaacc atgattgtgt ctagagaagc caagggttat tgtcaggggc acaacagccc      540
ccaaactgtc cctctcccca tcaatatccc atatacaggc tgagttccct gtgcctcact      600
gagaacaggg ctgtatctgg ttgtctatgg cgtgtatgta gctgtgcctg ggcaatggga      660
aatatagctt gcttcctgct ttctctcagc ctctgtcccc agagtcattt tgttctggga      720
ctggagtctt ccttctgtcc tcatcccttc ccctctgttt acacaggtca aggccaggca      780
ttggccacca aactgacttc tcaggaatgg gcaagcctgg gttacttgag agacttggct      840
ttttgaattt tcatttcaca gctctctgct ccttcagacg tcatgggggt ggggtgggga      900
ggacctaaag tccagtggtc agtgcgtgag ggcccagacc caaaggcccg gggccacagt      960
ctggtgcggt taggctcctc cctgcctctg cccgtgtttg cacccccagg cctgccctgg     1020
gattttggct gaggtcacag tccagcatga ccccactgaa cactatcctg tgccctgccc     1080
cagcaggcag ggtttcaaat gcctttgctc ccatcctttg tgatacaggt gacagaactg     1140
gggcccaaag aagggtaaac cttagactga gttccaaatt ggccatcttt attggagatc     1200
ctaactccca cactcctctc catgtggcca tttccagtca ctggatgttt aatcaatgac     1260
agatattagc agataaatgg cagtcatgga aaatgcctca gacaaggcat ggattgaaat     1320
cctggttttg ctactttgta acctcacaca ggtgtccaag cctgtggatt taataagcct     1380
atgttcaaaa agcaattagc atggtccctg acaagcaaga gctcagaaag attctggcta     1440
caattgttat tactggtacc tctttggagg ccaagcttcg ggcccaaggc aggtagggga     1500
ctcctcctta ccttcaaaga attttcatgg cgggaggtgg tggcgagggg acaagtagtg     1560
agatgagcaa ataaaagcta tttctgtgca ttgtggtcac tgtggccata ggaggggtcc     1620
caaagccaga tgaaggaccc aaagccaggc cacagagtac atctgtcctg tgcatgcact     1680
gcaaaaaggc acctagcaaa gggagctagg aagctgaaag gcagtctgtg acctccttca     1740
tggtttcctg tatctgccaa aagtgggtac ctttttctga tttgcacaaa ggctagtggt     1800
ggccctgtag gtatggccca aactcaggct ggaagtggca gtctgagatg gttcccaggt     1860
gatatgtgct cctggtcttc catgaggagt tcatgaggtg agcttgatga ggcctatctt     1920
ggcagaggga atggtacatg caaagctctg gaaatctgga gaggagtctt ggggtgtcag     1980
agggaactgc cagtgttaga tggcattggt cagcagggcc tggcagggaa gagagtcagt     2040
tagggaagcc aggctgagta gggtagtctg tgaggaacca ctgcaggatg tgaagcagat     2100
gagcctcact ggaggctgtg gaaagcctcc ctagaatagc acatggcctc aggggtttga     2160
gaacagctct gatgccaatc tcatttcagt ttcctcatct gaataatggg gatgacatta     2220
ttgcaggggc tgctataagg gctaaataag ataatgtacc ttaactgttt agcacaatgc     2280
cctgctcagg gtaagggctg cacaaatacc agccatgggt attatcagca ggatccagga     2340
gagcacactc cagggtcccg ggtggacgca cccctcccta gaagacaagg ctggtgatgc     2400
aggggccatc tcccccagcg gtgctggaga ctgaaggagc ttcttcctga cttgaaggct     2460
gattggttca aaaaactcag caaaaagttt aatagcaagg tgagacttca attctccttt     2520
ttgaggtagg cagaggtggg agaatagtga accaagcttc ccttcttctt ggggaagggg     2580
gctgtggtgg ggacagtctc acccaagggc agagatcctc accccatcct tcctggatgt     2640
cccccgcttg tctcattggc atctgtggtg gagagttctt tgtggatggc ttgcacatga     2700
cattttctgt ttctgtaaca ctttctgtgt ggacaattct gtccttttcc tctgtggctc     2760
ccatatgggt tggataggtg acagtctagg tctccctccc aaggtgttaa tttccagcaa     2820
gggaaaactc caagatccac cccctaaact gggccagaca agtcaacacc ccttccctga     2880
ggaagccatc accactggga ccacctggcc ttcctccatt gcagcctgtg gatccctggc     2940
ctcccgcctg agttgggggt gggggtggag gcataagtct gaaaaaaaag tgggtaatag     3000
tcagcagttc cctaaagtag aattactacc caccctctgc catggacccc agcataaagc     3060
tttttgtggg gcgtgcatga cctgactctg tactggcgtt aggcttcagg agatctgtgg     3120
aatagagttt gacttcatgg atcctaaccc tctgagacct gctgctgact cccagggagc     3180
aggtcctccc tcacagtctg tgcctcagct tccccagaaa aggtagatgg aggtgagtta     3240
aatgcttgga gatcctacac ctgggctttt gcttcctttt tccttgcacg gtcagtgccc     3300
aacacagtgc ctgacattca cactgaggcc cagcatacct atctttaagc agtttggaag     3360
tgatcttctg ggggtgatgg gcgtcttaaa acggtttcca tagcaagcac cttactttta     3420
ctcacatggg atgtttgttt ggaggggggc attaaaagga ctgctggcaa ggaggagaga     3480
gactaaacgc ctccccaagg gagccatttc ttggcatagt agttaaggga gaccacttct     3540
cagcattcgg aaggaactgg ttgggagcag gtgtccacga tgtctgggga ggggtcactt     3600
cgtgtggtct tggatatcag gagtggcaga gaggcaacac attccagatg agctctgccc     3660
tttgacacct ccccccaccc caccccggct gggtcaaggc cccaaggcca catatagaag     3720
gcgtggaagg tgggcaccag ctgctgctgc caggagatcc atgctccata agccctcgcg     3780
ccagcctcgg agacagccag gctgcgcaga gcagaggaga ggaagcagcg aggtgggaga     3840
cagtttcgct tctcccaccg aggccgcgcc tgtggctgca ggcgcccgga tcgccacagt     3900
taactccctg ttatctgggc cccaatcgat ctcaggctgt aacgtttaac cctaggctga     3960
cttccccaac cgccctcccc ctctccctcc cctgcttggg tctggggact gcgttttctt     4020
cgcctcgcag aggaaggtcg gccttgcaca aatccgcccc cacgaatccc aaagaattgg     4080
agaaaacttc cactttggga ttatatgcag ttgggattat atgagcccgg ggcttgcacc     4140
atgggtacgt gaggtgaaga catctgcagc agcaggatta attagcctaa gatgggcata     4200
tggaggccac tgatggagtg aaagcgggat atgcgggccc aactctgtcc ccactgggcg     4260
cctactctgg caaggctgag ttttccttct gtctttcaat cagtacctat tgagcgctgc     4320
tgttccaagc attgtttcgg gttttgagtg cgtaggccat ggtctcaggg caccaaatgt     4380
acgtagtcgt tttagccccg ggactcaaga gttgaggctg atgcctgcct gagagataaa     4440
atatcctttc tcggatcagt ttcctcacct gagaaatggg aacgggaatc tccgcccctt     4500
ttctcccggg gccctagtgc ccactgaatc cattaaggag ctcttggaag ggtggggtct     4560
tggaacacgc gtctacctcc caggaccctc gactaggaat ctctggcccg ccgcgcacct     4620
gagctggggg gcgcggccaa attctccctc ccggtcctcg aagcttctgg ccccgctcta     4680
gagggggcag aaagatagca gatttccccg gaggtgcgtc tctaaaccca gaccgcctca     4740
ccaaagcggg gaggtcgtcc tttttttttt ttttttgtaa agttgcggga aataggcgaa     4800
gacggggcgc gcaagggagc tgagcctggg tggaccgcgt cagggcgcgg ggagctcgag     4860
gcgcagcggc tgcagctccg gcctcagagc ccgcggcgtc caagtggccc gagctgcgct     4920
gggagggagg cggcgggagg agggagggga gccgaggtgg agggggttgg ggggaggagg     4980
gagcggcgag tccggtccgg                                                 5000
<210>  6
<211>  18
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic primer
<400>  6
tccgctgctc tggagaag                                                     18
<210>  7
<211>  20
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic primer
<400>  7
cacacgagca gtgacattgc                                                   20
<210>  8
<211>  15
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic primer
<400>  8
atgcgctacg tcgcc                                                        15
<210>  9
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  synthetic primer
<400>  9
ttaatcaaaa aggccaaatc ccat                                              24
<210>  10
<211>  17
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic primer
<400>  10
cagctggagc cccacag                                                      17
<210>  11
<211>  19
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic primer
<400>  11
gaggtcccag gtcctgagc                                                    19
<210>  12
<211>  21
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthtic primer
<400>  12
gtgcccacaa tcatggagga g                                                 21
<210>  13
<211>  20
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic primer
<400>  13
catcctcctc cagcactgtg                                                   20
<210>  14
<211>  18
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic primer
<400>  14
ctgctcctgg ccctcatc                                                     18
<210>  15
<211>  22
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthtic primer
<400>  15
gacccccttc actcatcatg tc                                                22
<210>  16
<211>  20
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  artificial sequence
<400>  16
aacccaaagc tgccctctcc                                                   20
<210>  17
<211>  29
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  artificial sequence
<400>  17
agctgaatgg aaaaaacatt gaagacgtc                                         29
<210>  18
<211>  19
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  artificial sequence
<400>  18
gcacaaaagt ggtgctgtg                                                    19
<210>  19
<211>  17
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  artificial sequence
<400>  19
gcgtggtgca ggagcat                                                      17
<210>  20
<211>  22
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  artificial sequence
<400>  20
gcagtctgag atggttccca gg                                                22
<210>  21
<211>  22
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  artificial sequence
<400>  21
tgcatgtacc attccctctg cc                                                22
<210>  22
<211>  22
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  artificial sequence
<400>  22
tcctgggagt tggtgatgtc ag                                                22
<210>  23
<211>  20
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  artificial sequence
<400>  23
aaaccctgct cggatcgctc                                                   20
<210>  24
<211>  46
<212>  PRT
<213>  Homo sapiens
<400>  24
Lys Lys Lys Arg Lys Arg Cys Gly Met Cys Ala Pro Cys Arg Arg Arg 
1               5                   10                  15      
Ile Asn Cys Glu Gln Cys Ser Ser Cys Arg Asn Arg Lys Thr Gly His 
20                  25                  30          
Gln Ile Cys Lys Phe Arg Lys Cys Glu Glu Leu Lys Lys Lys 
35                  40                  45      
<210>  25
<211>  46
<212>  PRT
<213>  Homo sapiens
<400>  25
Lys Lys Lys Arg Lys Arg Cys Gly Val Cys Val Pro Cys Lys Arg Leu 
1               5                   10                  15      
Ile Asn Cys Gly Val Cys Ser Ser Cys Arg Asn Arg Lys Thr Gly His 
20                  25                  30          
Gln Ile Cys Lys Phe Arg Lys Cys Glu Glu Leu Lys Lys Lys 
35                  40                  45      
<210>  26
<211>  45
<212>  PRT
<213>  Homo sapiens
<400>  26
Arg Lys Lys Arg Lys Arg Cys Gly Thr Cys Glu Pro Cys Arg Arg Leu 
1               5                   10                  15      
Glu Asn Cys Gly Ala Cys Thr Ser Cys Thr Asn Arg Arg Thr His Gln 
20                  25                  30          
Ile Cys Lys Leu Arg Lys Cys Glu Val Leu Lys Lys Lys 
35                  40                  45  
<210>  27
<211>  46
<212>  PRT
<213>  Homo sapiens
<400>  27
Lys Lys Lys Arg Lys Arg Cys Gly Val Cys Glu Pro Cys Gln Gln Lys 
1               5                   10                  15      
Thr Asn Cys Gly Glu Cys Thr Tyr Cys Lys Asn Arg Lys Asn Ser His 
20                  25                  30          
Gln Ile Cys Lys Lys Arg Lys Cys Glu Glu Leu Lys Lys Lys 
35                  40                  45      
<210>  28
<211>  52
<212>  PRT
<213>  Homo sapiens
<400>  28
Gly Arg Arg Ser Arg Arg Cys Gly Gln Cys Pro Gly Cys Gln Val Pro 
1               5                   10                  15      
Glu Asp Cys Gly Val Cys Thr Asn Cys Leu Asp Lys Pro Lys Phe Gly 
20                  25                  30          
Gly Arg Asn Ile Lys Lys Gln Cys Cys Lys Met Arg Lys Cys Gln Asn 
35                  40                  45              
Leu Gln Trp Met 
50          
<210>  29
<211>  52
<212>  PRT
<213>  Homo sapiens
<400>  29
Lys Met Arg Met Ala Arg Cys Gly His Cys Arg Gly Cys Leu Arg Val 
1               5                   10                  15      
Gln Asp Cys Gly Ser Cys Val Asn Cys Leu Asp Lys Pro Lys Phe Gly 
20                  25                  30          
Gly Pro Asn Thr Lys Lys Gln Cys Cys Val Tyr Arg Lys Cys Asp Lys 
35                  40                  45              
Ile Glu Ala Arg 
50          
<210>  30
<211>  52
<212>  PRT
<213>  Homo sapiens
<400>  30
Met Phe Lys Arg Val Gly Cys Gly Glu Cys Ala Ala Cys Gln Val Thr 
1               5                   10                  15      
Glu Asp Cys Gly Ala Cys Ser Thr Cys Leu Leu Gln Leu Pro His Asp 
20                  25                  30          
Val Ala Ser Gly Leu Phe Cys Lys Cys Glu Arg Arg Arg Cys Leu Arg 
35                  40                  45              
Ile Val Glu Arg 
50          
<210>  31
<211>  50
<212>  PRT
<213>  Homo sapiens
<400>  31
Val Glu Arg Ser Arg Gly Cys Gly Val Cys Arg Gly Cys Gln Thr Gln 
1               5                   10                  15      
Glu Asp Cys Gly His Cys Pro Ile Cys Leu Arg Pro Pro Arg Pro Gly 
20                  25                  30          
Leu Arg Arg Gln Trp Lys Cys Val Gln Arg Arg Cys Leu Arg Gly Lys 
35                  40                  45              
His Ala 
50  
<210>  32
<211>  52
<212>  PRT
<213>  Homo sapiens
<400>  32
Arg Arg Gln Asn Arg Lys Cys Gly Ala Cys Ala Ala Cys Leu Arg Arg 
1               5                   10                  15      
Met Asp Cys Gly Arg Cys Asp Phe Cys Cys Asp Lys Pro Lys Phe Gly 
20                  25                  30          
Gly Ser Asn Gln Lys Arg Gln Lys Cys Arg Trp Arg Gln Cys Leu Gln 
35                  40                  45              
Phe Ala Met Lys 
50          
<210>  33
<211>  52
<212>  PRT
<213>  Homo sapiens
<400>  33
Lys Arg Ser Ala Arg Met Cys Gly Glu Cys Glu Ala Cys Arg Arg Thr 
1               5                   10                  15      
Glu Asp Cys Gly His Cys Asp Phe Cys Arg Asp Met Lys Lys Phe Gly 
20                  25                  30          
Gly Pro Asn Lys Ile Arg Gln Lys Cys Arg Leu Arg Gln Cys Gln Leu 
35                  40                  45              
Arg Ala Arg Glu 
50          
<210>  34
<211>  51
<212>  PRT
<213>  Homo sapiens
<400>  34
Ala Phe Lys Arg Arg Arg Cys Gly Val Cys Glu Val Cys Gln Gln Pro 
1               5                   10                  15      
Glu Cys Gly Lys Cys Lys Ala Cys Lys Asp Met Val Lys Phe Gly Gly 
20                  25                  30          
Ser Gly Arg Ser Lys Gln Ala Cys Gln Glu Arg Arg Cys Pro Asn Met 
35                  40                  45              
Ala Met Lys 
50      
<210>  35
<211>  51
<212>  PRT
<213>  Homo sapiens
<400>  35
Arg Arg Arg Arg Thr Arg Cys Arg Lys Cys Glu Ala Cys Leu Arg Thr 
1               5                   10                  15      
Glu Cys Gly Glu Cys His Phe Cys Lys Asp Met Lys Lys Phe Gly Gly 
20                  25                  30          
Pro Gly Arg Met Lys Gln Ser Cys Ile Met Arg Gln Cys Ile Ala Pro 
35                  40                  45              
Val Leu Pro 
50      
<210>  36
<211>  51
<212>  PRT
<213>  Homo sapiens
<400>  36
Arg Arg Arg Arg Val Arg Cys Arg Lys Cys Lys Ala Cys Val Gln Gly 
1               5                   10                  15      
Glu Cys Gly Val Cys His Tyr Cys Arg Asp Met Lys Lys Phe Gly Gly 
20                  25                  30          
Pro Gly Arg Met Lys Gln Ser Cys Val Leu Arg Gln Cys Leu Ala Pro 
35                  40                  45              
Arg Leu Pro 
50      
<210>  37
<211>  51
<212>  PRT
<213>  Homo sapiens
<400>  37
Arg Arg Arg Arg Thr Arg Cys Arg Arg Cys Arg Ala Cys Val Arg Thr 
1               5                   10                  15      
Glu Cys Gly Asp Cys His Phe Cys Arg Asp Met Lys Lys Phe Gly Gly 
20                  25                  30          
Pro Gly Arg Met Lys Gln Ser Cys Leu Leu Arg Gln Cys Thr Ala Pro 
35                  40                  45              
Val Leu Pro 
50