【手続補正書】
【提出日】平成16年1月21日(2004.1.21)
【手続補正１】
【補正対象書類名】特許請求の範囲
【補正対象項目名】請求項５
【補正方法】変更
【補正の内容】
【請求項５】
アミノ酸配列が、
2004516003.tif 000001
2004516003.tif 000002
2004516003.tif 000003
(ここでAはHyp、ThrおよびSerから選択され、かつBはHypおよびLeuから選択される)、配列番号：131ならびに配列番号：133から選択される、請求項1記載のポリペプチド。
【手続補正２】
【補正対象書類名】明細書
【補正対象項目名】０１８３
【補正方法】変更
【補正の内容】
【０１８３】
【表４】  HRGP合成遺伝子モジュールの実例
2004516003.tif 000004
2004516003.tif 000005
2004516003.tif 000006
2004516003.tif 000007
【手続補正３】
【補正対象書類名】明細書
【補正対象項目名】０１９７
【補正方法】変更
【補正の内容】
【０１９７】
実施例6
GAGP構築物を組み入れた合成HRGP遺伝子カセットの構築
連続的および非連続的なHypモジュールをコードする合成遺伝子カセットを、いずれも相補的な「付着」末端を有する、「内部反復配列の対」および「外部3'-リンカーおよび5'-リンカーの対」それぞれの、オリゴヌクレオチド対からなる部分的に重複した組を用いて構築した。以下の5'-リンカー二重鎖、内部反復配列二重鎖および3'-リンカー二重鎖を用いた：
2004516003.tif 000008
2004516003.tif 000009
上記の構築物を用いて、タバコおよびトマトの細胞培養物ならびにタバコ植物体において、以下の合成遺伝子(配列番号：106)が最終的に発現された（配列番号：107）：
2004516003.tif 000010
【手続補正４】
【補正対象書類名】明細書
【補正対象項目名】０２０６
【補正方法】変更
【補正の内容】
【０２０６】
実施例7
SP構築物を組み入れた合成HRGP遺伝子カセットの構築
連続的および非連続的なHypモジュールをコードする合成遺伝子カセットを、いずれも相補的な「付着」末端を有する「内部反復配列の対」および「外部3'-リンカーおよび5'-リンカーの対」それぞれの、オリゴヌクレオチド対からなる部分的に重複した組を用いて構築した。以下の5'-リンカー、内部反復配列および3'-リンカーの二重鎖を用いた：
2004516003.tif 000011
上記の構築物を用いて、タバコおよびトマトの細胞培養物ならびにタバコ植物体において、以下の合成遺伝子(配列番号：111)が最終的に発現された（配列番号：236）：
2004516003.tif 000012
【手続補正５】
【補正対象書類名】明細書
【補正対象項目名】０３８８
【補正方法】変更
【補正の内容】
【０３８８】
以上から、本発明が植物ゴムの生産に関する問題に対して、新たなアプローチおよび解決を提供することは明らかであると考えられる。本アプローチは環境要因に依存せず、種々の天然ゴム、ならびにデザイナーゴムの生産を非常に容易にする。
【配列表】
SEQUENCE LISTING
<110>  OHIO UNIVERSITY
<120>  Synthetic Genes for Plant Gums and Other Hydroxyproline-Rich Glycoproteins
<140>  JP   2001-575817
<141>  2001-04-12
<150>  US   09/547,693
<151>  2000-04-12
<160>  244
<170> PatentIn version 3.0
<210>  1
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<400>  1
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His
<210>  2
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<400>  2
Ser Pro Pro Pro Thr Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His
<210>  3
<211>  5
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<400>  3
Ser Pro Pro Pro Pro
1               5
<210>  4
<211>  5
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<400>  4
Pro Pro Val Tyr Lys
1               5
<210>  5
<211>  5
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  Xaa can be Thr, Glu, hydroxyproline, Pro, His, and Ile.
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<400>  5
Xaa Pro Val Tyr Lys
1               5
<210>  6
<211>  5
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  Xaa can be Thr, Glu, hydroxyproline, Pro, His and Ile.
<400>  6
Pro Pro Val Xaa Lys
1               5
<210>  7
<211>  5
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (3)..(3)
<223>  Xaa can be Thr, Glu, hydroxyproline, Pro, His and Ile.
<400>  7
Pro Pro Xaa Tyr Lys
1               5
<210>  8
<211>  5
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (3)..(3)
<223>  Xaa can be Thr, Glu, hydroxyproline, Pro, His and Ile.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  Xaa can be Thr, Glu, hydroxyproline, Pro, His and Ile.
<400>  8
Pro Pro Xaa Tyr Xaa
1               5
<210>  9
<211>  4
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  Xaa can be Ser, Thr, and Ala.
<220>
<221>  SITE
<222>  (3)..(3)
<223>  Xaa can be Ser, Thr, and Ala.
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<400>  9
Xaa Pro Xaa Pro
1
<210>  10
<211>  30
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  10
ccaccacctt cacctccacc cccatctcca                                      30
<210>  11
<211>  30
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  11
tcaccatcac catctccttc gccatcaccc                                      30
<210>  12
<211>  123
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  12
gctggatcct caacccgggc ctcaccacca ccaccttcac ctccaccccc atctccacca     60
ccaccttcac ctccaccccc atctccacca ccaccttcac cggtcgcccg gaattcacca    120
ccc                                                                  123
<210>  13
<211>  12
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(10)
<223>  The Proline at these positions is a hydroxyproline.
<400>  13
Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro Gly Pro
1               5                   10
<210>  14
<211>  34
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  14
Met Gly Lys Met Ala Ser Leu Phe Ala Thr Phe Leu Val Val Leu Val
1               5                   10                  15
Ser Leu Ser Leu Ala Gln Thr Thr Arg Val Val Pro Val Ala Ser Ser
20                  25                  30
Ala Pro
<210>  15
<211>  4
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  15
Gly Ala Gly Pro
1
<210>  16
<211>  18
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  16
Ser Pro Pro Pro Pro Leu Ser Pro Ser Leu Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro
<210>  17
<211>  18
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  17
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro
<210>  18
<211>  23
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (21)..(23)
<223>  The Proline at these positions is a hydroxyproline.
<400>  18
Ser Pro Pro Pro Thr Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His Ser Pro Pro Pro
20
<210>  19
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  19
Ser Pro Pro Pro Ser Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Thr
1               5                   10                  15
Gly Pro His
<210>  20
<211>  13
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(10)
<223>  The Proline at these positions is a hydroxyproline.
<400>  20
Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro Gly Pro His
1               5                   10
<210>  21
<211>  13
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(9)
<223>  The Proline at these positions is a hydroxyproline.
<400>  21
Ser Pro Ser Pro Ala Pro Thr Pro Pro Leu Gly Pro His
1               5                   10
<210>  22
<211>  13
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(9)
<223>  The Proline at these positions is a hydroxyproline.
<400>  22
Ser Pro Leu Pro Thr Pro Thr Pro Pro Leu Gly Pro His
1               5                   10
<210>  23
<211>  13
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(9)
<223>  The Proline at these positions is a hydroxyproline.
<400>  23
Ser Pro Ser Pro Thr Pro Thr Pro Pro Leu Gly Pro His
1               5                   10
<210>  24
<211>  13
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(3)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(9)
<223>  The Proline at these positions is a hydroxyproline.
<400>  24
Ser Pro Pro Leu Thr Pro Thr Pro Pro Leu Leu Pro His
1               5                   10
<210>  25
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<400>  25
Ser Pro Leu Pro Thr Leu Ser Pro Leu Pro Ala Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His
<210>  26
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<400>  26
Ser Pro Leu Pro Thr Leu Ser Pro Leu Pro Thr Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His
<210>  27
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  27
Ser Pro Pro Pro Thr Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro His
<210>  28
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  28
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro His
<210>  29
<211>  12
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  29
Ala Gly Ser Ser Thr Arg Ala Ser Pro Pro Pro Pro
1               5                   10
<210>  30
<211>  27
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  30
gctggatcct caacccgggc ctcacca                                         27
<210>  31
<211>  36
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  31
aggtggtggt ggtgagcccc gggttgagga tccagc                               36
<210>  32
<211>  12
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  32
Pro Pro Pro Ser Pro Val Ala Arg Asn Ser Pro Pro
1               5                   10
<210>  33
<211>  36
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  33
ccaccacctt caccggtcgc ccggaattca ccaccc                               36
<210>  34
<211>  27
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  34
gggtggtgaa ttccgggcga ccggtga                                         27
<210>  35
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  35
ccaccacctt aatagagctc cccc                                            24
<210>  36
<211>  15
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  36
gggggagctc tatta                                                      15
<210>  37
<211>  10
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  37
Pro Pro Pro Ser Pro Pro Pro Pro Ser Pro
1               5                   10
<210>  38
<211>  30
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  38
ccaccacctt cacctccacc cccatctcca                                      30
<210>  39
<211>  30
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  39
aggtggtggt ggagatgggg gtggaggtga                                      30
<210>  40
<211>  11
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  40
Ala Ala Gly Ser Ser Thr Arg Ala Ser Pro Ser
1               5                   10
<210>  41
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  41
gctgccggat cctcaacccg ggcc                                            24
<210>  42
<211>  33
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  42
tgacggtgag gcccgggttg aggatccggc agc                                  33
<210>  43
<211>  11
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  43
Ser Pro Ser Pro Val Ala Arg Asn Ser Pro Pro
1               5                   10
<210>  44
<211>  33
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  44
tcaccctcac cggtcgcccg gaattcacca ccc                                  33
<210>  45
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  45
gggtggtgaa ttccgggcga ccgg                                            24
<210>  46
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  46
tcaccctcat aatagagctc cccc                                            24
<210>  47
<211>  15
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  47
gggggagctc tatta                                                      15
<210>  48
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  48
Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro Gly Pro His Ser Pro Pro
1               5                   10                  15
Pro Thr Leu
<210>  49
<211>  57
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  49
tcaccctcac caactcctac cccaccacct ggtccacact caccaccacc aacattg        57
<210>  50
<211>  57
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  50
tgagggtgac aatgttggtg gtggtgagtg tggaccaggt ggtggggtag gagttgg        57
<210>  51
<211>  11
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<400>  51
Val Lys Pro Tyr His Pro Thr Pro Val Tyr Lys
1               5                   10
<210>  52
<211>  30
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  52
tcaccctcac catctccttc gccatcaccc                                      30
<210>  53
<211>  30
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  53
tgagggtgag ggtgatggcg aaggagatgg                                      30
<210>  54
<211>  30
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  54
gctccagcac ctgccccagc ccctgcacca                                      30
<210>  55
<211>  21
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  55
tggtgcaggg gctggggcag g                                               21
<210>  56
<211>  21
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  56
gctgccggat cctcaacccg g                                               21
<210>  57
<211>  30
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  57
tgctggagcc cgggttgagg atccggcagc                                      30
<210>  58
<211>  33
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  58
gctccagcac cggtcgcccg gaattcacca ccc                                  33
<210>  59
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  59
gggtggtgaa ttccgggcga ccgg                                            24
<210>  60
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  60
gctccagcat aatagagctc cccc                                            24
<210>  61
<211>  15
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  61
gggggagctc tatta                                                      15
<210>  62
<211>  42
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  62
acaccaaccc ctactcccac gccaacacct acacccactc ca                        42
<210>  63
<211>  42
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  63
ggttggtgtt ggagtgggtc taggtgttgg cgtgggagta gg                        42
<210>  64
<211>  21
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  64
gctgccggat cctcaacccg g                                               21
<210>  65
<211>  30
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  65
ggttggtgtc cgggttgagg atccggcagc                                      30
<210>  66
<211>  33
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  66
acaccaaccc cggtcgcccg gaattcacca ccc                                  33
<210>  67
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  67
gggtggtgaa ttccgggcga ccgg                                            24
<210>  68
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  68
acaccaacct aatagagctc cccc                                            24
<210>  69
<211>  15
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  69
gggggagctc tatta                                                      15
<210>  70
<211>  45
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  70
ccaccatcac caccctctcc tccatcaccc ccatccccac catca                     45
<210>  71
<211>  45
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  71
tgatggtggt gatggtgggg atgggggtga tggaggagag ggtgg                     45
<210>  72
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  72
gctgccggat cctcaacccg ggcc                                            24
<210>  73
<211>  33
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  73
tgatggtggg gcccgggttg aggatccggc agc                                  33
<210>  74
<211>  33
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  74
ccaccatcac cggtcgcccg gaattcacca ccc                                  33
<210>  75
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  75
gggtggtgaa ttccgggcga ccgg                                            24
<210>  76
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  76
ccaccatcat aatagagctc cccc                                            24
<210>  77
<211>  15
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  77
gggggagctc tatta                                                      15
<210>  78
<211>  48
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  78
ccaccacctt caccacctcc atctccccca ccttcccctc caccatca                  48
<210>  79
<211>  48
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  79
aggtggtggt gatggtggag gggaaggtgg gggagatgga ggtggtga                  48
<210>  80
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  80
gctggatcct caacccgggc ctca                                            24
<210>  81
<211>  33
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  81
aggtggtggt gaggcccggg ttgaggatcc agc                                  33
<210>  82
<211>  36
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  82
ccaccacctt caccggtcgc ccggaattca ccaccc                               36
<210>  83
<211>  27
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  83
gggtggtgaa ttccgggcga ccggtga                                         27
<210>  84
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  84
ccaccacctt aatagagctc cccc                                            24
<210>  85
<211>  15
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  85
gggggagctc tatta                                                      15
<210>  86
<211>  42
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  86
ccaccacctt caccctctcc acctccacca tctccgtcac ca                        42
<210>  87
<211>  42
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  87
aggtggtggt ggtgacggag atggtggagg tggagagggt ga                        42
<210>  88
<211>  48
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  88
ccaccacctt cacccccatc tccacctcca ccatctccac cgtcacca                  48
<210>  89
<211>  48
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  89
aggtggtggt ggtgacggtg gagatggtgg aggtggagat gggggtga                  48
<210>  90
<211>  60
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  90
ccaccaccta ctcccgttta caaatcacca ccaccaccta ctcccgttta caaatcacca     60
<210>  91
<211>  60
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  91
aggtggtggt ggtgatttgt aaacgggagt aggtggtggt ggtgatttgt aaacgggagt     60
<210>  92
<211>  48
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  92
ccaccacctg tcaagcctta ccaccccact cccgtttttc tttcacca                  48
<210>  93
<211>  48
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  93
aggtggtggt ggtgaaagaa aaacgggagt ggggtggtaa ggcttgac                  48
<210>  94
<211>  48
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  94
ccaccacctg tcttaccttt ccaccccact cccgtttaca aatcacca                  48
<210>  95
<211>  48
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  95
aggtggtggt ggtgatttgt aaacgggagt ggggtggaaa ggtaagac                  48
<210>  96
<211>  21
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  96
ggccgcgagc tccagcacgg g                                               21
<210>  97
<211>  17
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  97
cccgtgctgg agctcgc                                                    17
<210>  98
<211>  121
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  98
gatccgcaat gggaaaaatg gcttctctat ttgccacatt tttagtggtt ttagtgtcac     60
ttagcttagc acaaacaacc cgggtaccgg tcgccaccat ggtgtaaagc ggccgcgagc    120
t                                                                    121
<210>  99
<211>  113
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  99
cgcggccgct ttacaccatg gtggcgaccg gtacccgggt tgtttgtgct aagctaagtg     60
acactaaaac cactaaaaat gtggcaaata gagaagccat ttttcccatt gcg           113
<210>  100
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  100
Ser Pro Ser Pro Thr Pro Thr Ala Pro Pro Gly Pro His Ser Pro Pro
1               5                   10                  15
Pro Thr Leu
<210>  101
<211>  57
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  101
tcaccctcac caactcctac cgcaccacct ggtccacact ctccaccacc aacattg        57
<210>  102
<211>  57
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  102
caatgttggt ggtggagagt gtggaccagg tggtgcggta ggagttggtg agggtga        57
<210>  103
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  103
Ser Pro Ser Pro Thr Pro Thr Ala Pro Pro Gly Pro His Ser Pro Pro
1               5                   10                  15
Pro Ser Leu
<210>  104
<211>  57
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  104
tcaccctcac caactcctac cgcaccacct ggtccacact ctccaccacc atcattg        57
<210>  105
<211>  57
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  105
caatgatggt ggtggagagt gtggaccagg tggtgcggta ggagttggtg agggtga        57
<210>  106
<211>  279
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  106
ggatccgcaa tgggaaaaat ggcttctcta tttgccacat ttttagtcgt tttagtgtca     60
cttagcttag cacaaacaac ccgggactca ccctcaccaa ctcctaccgc accacctggt    120
ccacactctc caccaccaac attgtcaccc tcaccaactc ctaccgcacc acctggtcca    180
cactcaccac caccaacatt gtcaccctca ccaactccta ccgcaccacc tggtccacac    240
tcaccaccac catcattgtc accctcaccg gtcgccacc                           279
<210>  107
<211>  88
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  107
Met Gly Lys Met Ala Ser Leu Phe Ala Thr Phe Leu Val Val Leu Val
1               5                   10                  15
Ser Leu Ser Leu Ala Gln Thr Thr Arg Asp Ser Pro Ser Pro Thr Pro
20                  25                  30
Thr Ala Pro Pro Gly Pro His Ser Pro Pro Pro Thr Leu Ser Pro Ser
35                  40                  45
Pro Thr Pro Thr Ala Pro Pro Gly Pro His Ser Pro Pro Pro Thr Leu
50                  55                  60
Ser Pro Ser Pro Thr Pro Thr Ala Pro Pro Gly Pro His Ser Pro Pro
65                  70                  75                  80
Pro Ser Leu Ser Pro Ser Pro Val
85
<210>  108
<211>  13
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  108
Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser
1               5                   10
<210>  109
<211>  30
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  109
tcaccctcac catctccttc gccatcaccc                                      30
<210>  110
<211>  30
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  110
tgagggtgag ggtgatggcg aaggagatgg                                      30
<210>  111
<211>  288
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  111
ggatccgcaa tgggaaaaat ggcttctcta tttgccacat ttttagtggt tttagtgtca     60
cttagcttag cacaaacaac ccgggcctca ccctcaccat ctccttcgcc atcaccctca    120
ccctcaccat ctccttcgcc atcaccctca ccctcaccat ctccttcgcc atcaccctca    180
ccctcaccat ctccttcgcc atcaccctca ccctcaccat ctccttcgcc atcaccctca    240
ccctcaccat ctccttcgcc atcaccctca ccctcaccgg tcgccacc                 288
<210>  112
<211>  30
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  112
tcaccctcac catctccttc gccatcaccc                                      30
<210>  113
<211>  30
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  113
tgagggtgag ggtgatggcg aaggagatgg                                      30
<210>  114
<211>  10
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  114
Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro
1               5                   10
<210>  115
<211>  57
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  115
tcaccctcac caactcctac cgcaccacct ggtccacact caccaccacc aacattg        57
<210>  116
<211>  57
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  116
tgagggtgac aatgttggtg gtggtgagtg tggaccaggt ggtgcggtag gagttgg        57
<210>  117
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  117
Ser Pro Ser Pro Thr Pro Thr Ala Pro Pro Gly Pro His Ser Pro Pro
1               5                   10                  15
Pro Thr Leu
<210>  118
<211>  87
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  118
gctgccggat ccgcaatggg aaaaatggct tctctatttg ccacattttt agtggtttta     60
gtgtcactta gcttagcaca aacaacc                                         87
<210>  119
<211>  66
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  119
cccccgtctc gacgccagcg gtactacccg ggttgtttgt gctaagctaa gtgacactaa     60
aaccac                                                                66
<210>  120
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  120
gctgccggat cctcaacccg ggcc                                            24
<210>  121
<211>  33
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  121
tgagggtgag gcccgggttg aggatccggc agc                                  33
<210>  122
<211>  8
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  122
Ala Ala Gly Ser Ser Thr Arg Ala
1               5
<210>  123
<211>  33
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  123
tcaccctcac cggtcgcccg gaattcacca ccc                                  33
<210>  124
<211>  24
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  124
gggtggtgaa ttccgggcga ccgg                                            24
<210>  125
<211>  11
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  125
Ser Pro Ser Pro Val Ala Thr Asn Ser Pro Pro
1               5                   10
<210>  126
<211>  12
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<400>  126
Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro
1               5                   10
<210>  127
<211>  22
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(14)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (16)..(16)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (18)..(18)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (20)..(20)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (22)..(22)
<223>  The Proline at this position is a hydroxyproline.
<400>  127
Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro
1               5                   10                  15
Ser Pro Ser Pro Ser Pro
20
<210>  128
<211>  18
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (3)..(3)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (7)..(7)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(11)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (16)..(18)
<223>  The Proline at these positions is a hydroxyproline.
<400>  128
Asp Ser Pro Ser Pro Thr Pro Thr Ala Pro Pro Gly Pro His Ser Pro
1               5                   10                  15
Pro Pro
<210>  129
<211>  25
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (3)..(3)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (7)..(7)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(11)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (16)..(16)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (18)..(18)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (22)..(22)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (24)..(24)
<223>  The Proline at this position is a hydroxyproline.
<400>  129
Asp Ser Pro Ser Pro Thr Pro Thr Ala Pro Pro Gly Pro His Ser Pro
1               5                   10                  15
Pro Pro Thr Leu Ser Pro Ser Pro Thr
20                  25
<210>  130
<211>  139
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  130
gccaagcttc cggagtgccg gccctcatag cccacctcca ccattatcac catcacctac     60
tccaactcct cctttgggac cacacagtcc accccctaca ctttcccctt caccaacccc    120
aacaccaccc cccgggtac                                                 139
<210>  131
<211>  39
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  131
Gly Pro His Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr
1               5                   10                  15
Pro Pro Leu Gly Pro His Ser Pro Pro Pro Thr Leu Ser Pro Ser Pro
20                  25                  30
Thr Pro Thr Pro Pro Pro Gly
35
<210>  132
<211>  253
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  132
gccaagcttc cggagtgccg gccctcatag cccacctcca ccattatcac catcacctac     60
tccaactcct cctttgggac cacacagtcc accccctaca ctttcccctt caccaacccc    120
aacaccaccc cccggccctc atagcccacc tccaccatta tcaccatcac ctactccaac    180
tcctcctttg ggaccacaca gtccaccccc tacactttcc ccttcaccaa ccccaacacc    240
accccccggg tac                                                       253
<210>  133
<211>  77
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  133
Gly Pro His Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr
1               5                   10                  15
Pro Pro Leu Gly Pro His Ser Pro Pro Pro Thr Leu Ser Pro Ser Pro
20                  25                  30
Thr Pro Thr Pro Pro Pro Gly Pro His Ser Pro Pro Pro Pro Leu Ser
35                  40                  45
Pro Ser Pro Thr Pro Thr Pro Pro Leu Gly Pro His Ser Pro Pro Pro
50                  55                  60
Thr Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro Gly
65                  70                  75
<210>  134
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  The amino acid at this position is selected from Ser, Thr, and Al
a
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (3)..(3)
<223>  The amino acid at this position is selected from Hyp, Pro, Leu, a
nd Ile
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The amino acid at this position is selected from Pro and Hyp.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The amino acid at this position is selected from Hyp, Pro, Ser, T
hr, and Ala
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The amino acid at this position is selected from Leu and Ile.
<220>
<221>  SITE
<222>  (7)..(7)
<223>  The amino acid at this position is selected from Ser, Thr, and Al
a
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (9)..(9)
<223>  The amino acid at this position is selected from Ser, Leu, Hyp, T
hr, Ala, and Ile
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The amino acid at this position is selected from Hyp, Pro, Leu, a
nd Ile
<220>
<221>  SITE
<222>  (11)..(11)
<223>  The amino acid at this position is selected from Thr, Ala, and Se
r
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (13)..(13)
<223>  The amino acid at this position is selected from Thr, Ser, and Al
a
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (16)..(16)
<223>  The amino acid at this position is selected from Thr, Leu, Hyp, S
er, Ala, and Ile
<220>
<221>  SITE
<222>  (17)..(17)
<223>  The amino acid at this position is selected from Gly, Leu, Ala, a
nd Ile
<220>
<221>  SITE
<222>  (19)..(19)
<223>  The amino acid at this position is selected from His and Pro.
<400>  134
Xaa Pro Xaa Xaa Xaa Xaa Xaa Pro Xaa Xaa Xaa Pro Xaa Pro Pro Xaa
1               5                   10                  15
Xaa Pro Xaa
<210>  135
<211>  11
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (1)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<400>  135
Pro Pro Pro Pro Ser Ser Thr Pro Gly Leu His
1               5                   10
<210>  136
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  The amino acid at this position is selected from Ser, Thr, and Al
a
<220>
<221>  SITE
<222>  (3)..(3)
<223>  The amino acid at this position is selected from Hyp, Pro, Leu, a
nd Ile
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The amino acid at this position is selected from Pro and Hyp.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The amino acid at this position is selected from Hyp, Pro, Ser, T
hr, and Ala
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The amino acid at this position is selected from Leu and Ile.
<220>
<221>  SITE
<222>  (7)..(7)
<223>  The amino acid at this position is selected from Ser, Thr, and Al
a
<220>
<221>  SITE
<222>  (9)..(9)
<223>  The amino acid at this position is selected from Ser, Leu, Hyp, T
hr, Ala, and Ile
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The amino acid at this position is selected from Hyp, Pro, Leu, a
nd Ile
<220>
<221>  SITE
<222>  (11)..(11)
<223>  The amino acid at this position is selected from Thr, Ala, and Se
r
<220>
<221>  SITE
<222>  (13)..(13)
<223>  The amino acid at this position is selected from Thr, Ser, and Al
a
<220>
<221>  SITE
<222>  (16)..(16)
<223>  The amino acid at this position is selected from Thr, Leu, Hyp, S
er, Ala, and Ile
<220>
<221>  SITE
<222>  (17)..(17)
<223>  The amino acid at this position is selected from Gly, Leu, Ala, a
nd Ile
<220>
<221>  SITE
<222>  (19)..(19)
<223>  The amino acid at this position is selected from His and Pro.
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  136
Xaa Pro Xaa Xaa Xaa Xaa Xaa Pro Xaa Xaa Xaa Pro Xaa Pro Pro Xaa
1               5                   10                  15
Xaa Pro Xaa
<210>  137
<211>  6
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  The amino acid at this position is selected from Ser, Thr, and Al
a
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (3)..(3)
<223>  The amino acid at this position is selected from Ser, Leu, Hyp, T
hr, Ala, and Ile
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The amino acid at this position is selected from Hyp, Pro, Leu, a
nd Ile
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The amino acid at this position is selected from Thr, Ala, and Se
r
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<400>  137
Xaa Pro Xaa Xaa Xaa Pro
1               5
<210>  138
<211>  6
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<400>  138
Ser Pro Ser Pro Thr Pro
1               5
<210>  139
<211>  6
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  The amino acid at this position is selected from Ser, Thr, and Al
a
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (3)..(3)
<223>  The amino acid at this position is selected from Hyp, Leu, and Il
e
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The amino acid at this position is selected from Pro and Hyp.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The amino acid at this position is selected from Hyp, Ser, Thr, a
nd Ala
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The amino acid at this position is selected from Leu and Ile.
<400>  139
Xaa Pro Xaa Xaa Xaa Xaa
1               5
<210>  140
<211>  6
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The amino acid at this position is selected from Hyp, Thr, and Se
r
<400>  140
Ser Pro Pro Pro Xaa Leu
1               5
<210>  141
<211>  7
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  The amino acid at this position is selected from Thr, Ser, and Al
a
<220>
<221>  SITE
<222>  (2)..(3)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The amino acid at this position is selected from Thr, Leu, Hyp, S
er, Ala, and Ile
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The amino acid at this position is selected from Gly, Leu, Ala, a
nd Ile
<220>
<221>  SITE
<222>  (7)..(7)
<223>  The amino acid at this position is selected from His and Pro.
<400>  141
Xaa Pro Pro Xaa Xaa Pro Xaa
1               5
<210>  142
<211>  12
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (3)..(3)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (7)..(8)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (9)..(9)
<223>  The amino acid at this position is selected from Hyp and Leu.
<400>  142
Pro Ser Pro Thr Pro Thr Pro Pro Xaa Gly Pro His
1               5                   10
<210>  143
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  143
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro His
<210>  144
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<400>  144
Ser Pro Pro Pro Thr Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His
<210>  145
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  145
Ser Pro Pro Pro Ser Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Thr
1               5                   10                  15
Gly Pro His
<210>  146
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (19)..(19)
<223>  The Proline at this position is a hydroxyproline.
<400>  146
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro Pro
<210>  147
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<400>  147
Ser Pro Leu Pro Thr Leu Ser Pro Leu Pro Thr Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His
<210>  148
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<400>  148
Ser Pro Leu Pro Thr Leu Ser Pro Leu Pro Ala Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His
<210>  149
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (19)..(19)
<223>  The Proline at this position is a hydroxyproline.
<400>  149
Ser Pro Pro Pro Pro Leu Ser Pro Ser Leu Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro Pro
<210>  150
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<400>  150
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His
<210>  151
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<400>  151
Ser Pro Pro Pro Thr Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His
<210>  152
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<400>  152
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Ala Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His
<210>  153
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  153
Ser Pro Pro Pro Pro Leu Ser Pro Leu Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro His
<210>  154
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  154
Ser Pro Pro Pro Ser Leu Ser Pro Leu Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro His
<210>  155
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(9)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  155
Ser Pro Pro Pro Thr Leu Ser Pro Pro Leu Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Leu Pro His
<210>  156
<211>  16
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(2)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(7)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(13)
<223>  The Proline at these positions is a hydroxyproline.
<400>  156
Pro Pro Thr Leu Ser Pro Pro Leu Thr Pro Thr Pro Pro Leu Leu Pro
1               5                   10                  15
<210>  157
<211>  16
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  157
Ser Pro Pro Pro Ser Leu Ser Pro Leu Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
<210>  158
<211>  16
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(2)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (9)..(9)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (11)..(12)
<223>  The Proline at these positions is a hydroxyproline.
<400>  158
Pro Pro Leu Ser Pro Leu Pro Thr Pro Thr Pro Pro Leu Gly Pro His
1               5                   10                  15
<210>  159
<211>  14
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(14)
<223>  The Proline at this position is a hydroxyproline.
<400>  159
Ser Pro Pro Pro Thr Leu Ser Pro Ser Pro Thr Pro Thr Pro
1               5                   10
<210>  160
<211>  14
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (3)..(3)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (7)..(7)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (9)..(10)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(14)
<223>  The Proline at this position is a hydroxyproline.
<400>  160
Leu Ser Pro Ser Leu Thr Pro Thr Pro Pro Leu Gly Pro Pro
1               5                   10
<210>  161
<211>  14
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (9)..(9)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (11)..(13)
<223>  The Proline at these positions is a hydroxyproline.
<400>  161
Pro Thr Leu Ser Pro Leu Pro Ala Pro Thr Pro Pro Pro Gly
1               5                   10
<210>  162
<211>  12
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<400>  162
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro
1               5                   10
<210>  163
<211>  12
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(11)
<223>  The Proline at these positions is a hydroxyproline.
<400>  163
Ser Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Thr
1               5                   10
<210>  164
<211>  12
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(2)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<400>  164
Pro Pro Thr Leu Ser Pro Ser Pro Thr Pro Thr Pro
1               5                   10
<210>  165
<211>  10
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (3)..(3)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (5)..(6)
<223>  The Proline at these positions is a hydroxyproline.
<400>  165
Pro Thr Pro Thr Pro Pro Leu Gly Pro His
1               5                   10
<210>  166
<211>  10
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(2)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(7)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<400>  166
Pro Pro Thr Leu Ser Pro Pro Leu Thr Pro
1               5                   10
<210>  167
<211>  10
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<400>  167
Ser Pro Pro Pro Ser Leu Ser Pro Leu Pro
1               5                   10
<210>  168
<211>  8
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (3)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<400>  168
Pro Thr Pro Pro Leu Gly Pro His
1               5
<210>  169
<211>  8
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<400>  169
Pro Leu Ser Pro Ser Pro Ala Pro
1               5
<210>  170
<211>  8
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(3)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (7)..(7)
<223>  The Proline at this position is a hydroxyproline.
<400>  170
Pro Pro Pro Thr Leu Ser Pro Ser
1               5
<210>  171
<211>  6
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<400>  171
Thr Pro Pro Pro Gly Pro
1               5
<210>  172
<211>  6
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(2)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The Proline at this position is a hydroxyproline.
<400>  172
Pro Pro Leu Ser Pro Ser
1               5
<210>  173
<211>  6
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<400>  173
Ser Pro Leu Pro Ala Pro
1               5
<210>  174
<211>  6
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<400>  174
Leu Pro Thr Leu Ser Pro
1               5
<210>  175
<211>  4
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<400>  175
Ser Pro Ser Pro
1
<210>  176
<211>  4
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The proline at this position is a hydroxyproline.
<400>  176
Ser Pro Thr Pro
1
<210>  177
<211>  4
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<400>  177
Thr Pro Thr Pro
1
<210>  178
<211>  4
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<400>  178
Thr Pro Pro Pro
1
<210>  179
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The amino acid at this position is selected from Hyp, Thr, and Se
r
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (16)..(16)
<223>  The amino acid at this position is selected from Hyp and Leu.
<400>  179
Ser Pro Pro Pro Xaa Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Xaa
1               5                   10                  15
Gly Pro His
<210>  180
<211>  38
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (3)..(3)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (5)..(7)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (11)..(12)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (15)..(15)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (17)..(18)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (24)..(27)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (30)..(30)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (34)..(34)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (36)..(37)
<223>  The Proline at these positions is a hydroxyproline.
<400>  180
Gly Pro Pro Ser Pro Pro Pro Thr Leu Ser Pro Pro Leu Thr Pro Thr
1               5                   10                  15
Pro Pro Leu Leu Pro His Ser Pro Pro Pro Pro Leu Ser Pro Ser Leu
20                  25                  30
Thr Pro Thr Pro Pro Leu
35
<210>  181
<211>  38
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (5)..(8)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (11)..(11)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (13)..(13)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (15)..(15)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (17)..(19)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (24)..(26)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (30)..(30)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (34)..(34)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (36)..(37)
<223>  The Proline at these positions is a hydroxyproline.
<400>  181
Gly Pro His Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Ala Pro Thr
1               5                   10                  15
Pro Pro Pro Gly Pro His Ser Pro Pro Pro Ser Leu Ser Pro Leu Pro
20                  25                  30
Thr Pro Thr Pro Pro Leu
35
<210>  182
<211>  2
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(2)
<223>  The seq  Xaa-Pro is repeated x times, x being an integer from 2 t
o 1000.  Xaa is any amino acid other than hydroxyproline.  Each o
f the Proline residues is a hydroxyproline
<400>  182
Xaa Pro
1
<210>  183
<211>  6
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  Xaa is any amino acid other than hydroxyproline.
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is hydroxyproline.
<220>
<221>  SITE
<222>  (3)..(4)
<223>  Xaa at these positions is any amino acid other than hydroxyprolin
e
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The Proline at this position is hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  Xaa is any amino acid other than hydroxyproline.
<400>  183
Xaa Pro Xaa Xaa Pro Xaa
1               5
<210>  184
<211>  23
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (21)..(23)
<223>  The Proline at these positions is a hydroxyproline.
<400>  184
Ser Pro Pro Pro Thr Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His Ser Pro Pro Pro
20
<210>  185
<211>  24
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (21)..(24)
<223>  The Proline at these positions is a hydroxyproline.
<400>  185
Ser Pro Pro Pro Thr Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His Ser Pro Pro Pro Pro
20
<210>  186
<211>  16
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  UNSURE
<222>  (14)..(14)
<223>  Xaa is an amino acid which could not be identified.
<220>
<221>  SITE
<222>  (15)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<400>  186
Ser Pro Pro Pro Thr Leu Ser Pro Ser Pro Thr Pro Thr Xaa Pro Pro
1               5                   10                  15
<210>  187
<211>  16
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  UNSURE
<222>  (14)..(14)
<223>  Xaa is an amino acid which could not be identified.
<220>
<221>  SITE
<222>  (15)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<400>  187
Ser Pro Pro Pro Ser Leu Ser Pro Ser Pro Thr Pro Thr Xaa Pro Pro
1               5                   10                  15
<210>  188
<211>  12
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(10)
<223>  The Proline at these positions is a hydroxyproline.
<400>  188
Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro Gly Pro
1               5                   10
<210>  189
<211>  19
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  189
Ser Pro Pro Pro Ser Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Thr
1               5                   10                  15
Gly Pro His
<210>  190
<211>  18
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<400>  190
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro
<210>  191
<211>  19
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The proline at these positions is a hydroxyproline.
<400>  191
Ser Pro Leu Pro Thr Leu Ser Pro Leu Pro Ala Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His
<210>  192
<211>  19
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(16)
<223>  The Proline at these positions is a hydroxyproline.
<400>  192
Ser Pro Leu Pro Thr Leu Ser Pro Leu Pro Thr Pro Thr Pro Pro Pro
1               5                   10                  15
Gly Pro His
<210>  193
<211>  18
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  193
Ser Pro Pro Pro Pro Leu Ser Pro Ser Leu Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro
<210>  194
<211>  13
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(10)
<223>  The Proline at these positions is a hydroxyproline.
<400>  194
Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro Gly Pro His
1               5                   10
<210>  195
<211>  13
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(9)
<223>  The Proline at these positions is a hydroxyproline.
<400>  195
Ser Pro Ser Pro Ala Pro Thr Pro Pro Leu Gly Pro His
1               5                   10
<210>  196
<211>  14
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(9)
<223>  The Proline at these positions is a hydroxyproline.
<400>  196
Ser Pro Leu Pro Thr Pro Thr Pro Pro Leu Gly Pro His Ser
1               5                   10
<210>  197
<211>  13
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(9)
<223>  The Proline at these positions is a hydroxyproline.
<400>  197
Ser Pro Ser Pro Thr Pro Thr Pro Pro Leu Gly Pro His
1               5                   10
<210>  198
<211>  13
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (2)..(3)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (6)..(6)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(9)
<223>  The Proline at these positions is a hydroxyproline.
<400>  198
Ser Pro Pro Leu Thr Pro Thr Pro Pro Leu Leu Pro His
1               5                   10
<210>  199
<211>  11
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (1)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<400>  199
Pro Pro Pro Pro Ser Ser Thr Pro Gly Leu His
1               5                   10
<210>  200
<211>  1
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (1)..(1)
<223>  The Proline is hydroxyproline linked to Ara Ara Ara Ara.
<400>  200
Pro
1
<210>  201
<211>  1
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (1)..(1)
<223>  The Proline is hydroxyproline linked to Ara Ara Ara.
<400>  201
Pro
1
<210>  202
<211>  1
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (1)..(1)
<223>  The Proline is hydroxyproline linked to Ara Ara.
<400>  202
Pro
1
<210>  203
<211>  1
<212>  PRT
<213>  Acacia senegal
<220>
<221>  SITE
<222>  (1)..(1)
<223>  The Proline is hydroxyproline linked to Ara.
<400>  203
Pro
1
<210>  204
<211>  30
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  204
gataccgcga gacccacgct caccagctcc                                      30
<210>  205
<211>  21
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  205
ctcggtcgcc gcatacacta t                                               21
<210>  206
<211>  87
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  206
ggcaagcttc cggagtgccg gccctcatag cccacctcca ccattatcac catcacctac     60
tccaactcct cctttgggac cacacag                                         87
<210>  207
<211>  72
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  207
ggtcccgggg ggtggtgttg gggttggtga aggggaaagt gtagggggtg gactgtgtgg     60
tcccaaagga gg                                                         72
<210>  208
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  208
Ser Pro Ser Pro Thr Pro Thr Pro Pro Pro Gly Pro His Ser Pro Pro
1               5                   10                  15
Pro Thr Leu
<210>  209
<211>  3
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  Xaa is any amino acid other than hydroxyproline.
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (3)..(3)
<223>  The hydroxyproline at this position is repeated n times, n being
an integer from 1 to 100.  Each of the proline residues at positi
ons 3 - 102 is hydroxyproline
<400>  209
Xaa Pro Pro
1
<210>  210
<211>  3
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (1)..(1)
<223>  Xaa at this position is any amino acid other than hydroxyproline.
<220>
<221>  SITE
<222>  (3)..(3)
<223>  The hydroxyproline at this position is repeated n times, n being
an integer from 1 to 100.   Each of the proline residues at posit
ions 3 - 102 is hydroxyproline
<400>  210
Xaa Pro Pro
1
<210>  211
<211>  3
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(3)
<223>  The Proline at these positions is a hydroxyproline.
<400>  211
Ser Pro Pro
1
<210>  212
<211>  4
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<400>  212
Ser Pro Pro Pro
1
<210>  213
<211>  3
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(3)
<223>  The Proline at these positions is a hydroxyproline.
<400>  213
Thr Pro Pro
1
<210>  214
<211>  4
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<400>  214
Thr Pro Pro Pro
1
<210>  215
<211>  4
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(3)
<223>  The Proline at these positions is a hydroxyproline.
<400>  215
Ser Pro Pro Pro
1
<210>  216
<211>  5
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(3)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The Proline at this position is a hydroxyproline.
<400>  216
Ser Pro Pro Pro Pro
1               5
<210>  217
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  217
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro His
<210>  218
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(3)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  218
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro His
<210>  219
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(4)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  219
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro His
<210>  220
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  220
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro His
<210>  221
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(4)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  221
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro His
<210>  222
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(3)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (5)..(5)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  222
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro His
<210>  223
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(10)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  223
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro His
<210>  224
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  224
Ser Pro Pro Pro Pro Leu Ser Pro Ser Pro Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro His
<210>  225
<211>  19
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (8)..(8)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (12)..(12)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(15)
<223>  The Proline at these positions is a hydroxyproline.
<400>  225
Ser Pro Pro Pro Pro Leu Ser Pro Ser Leu Thr Pro Thr Pro Pro Leu
1               5                   10                  15
Gly Pro His
<210>  226
<211>  23
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  226
gaagatggtg cgctcctgga cgt                                             23
<210>  227
<211>  38
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  227
ctctttttct ctggatccgg tctatatttt cttttagc                             38
<210>  228
<211>  37
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  228
cgggtgctgc ccgggttgtc tgacccgtga cacttgc                              37
<210>  229
<211>  334
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  229
ggatccgcaa tgggaaaaat ggcttctcta tttgccacat ttttagtggt tttaggtgtc     60
acttagctta gcacaaacaa cccgggcccc accttcaccc ccatctccac cgagtccacc    120
atccccacct tcacccccat ctccaccgag tccaccatcc ccaccttcac ccccatctcc    180
accgagtcca ccatccccac cttcaccccc atctccaccg agtccaccat ccccaccttc    240
acccccatct ccaccgagtc caccatcccc accttcaccc ccatctccac cgagtccacc    300
atccccacct tcatccatgg cataatagag ctcg                                334
<210>  230
<211>  105
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  230
Ser Ala Met Gly Lys Met Ala Ser Leu Phe Ala Thr Phe Leu Val Val
1               5                   10                  15
Leu Val Ser Leu Val Leu Ala Gln Thr Thr Arg Ala Pro Pro Ser Pro
20                  25                  30
Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro
35                  40                  45
Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser
50                  55                  60
Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro
65                  70                  75                  80
Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro
85                  90                  95
Ser Pro Pro Ser Pro Ser Ser Met Ala
100                 105
<210>  231
<211>  72
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<220>
<221>  SITE
<222>  (2)..(2)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (4)..(5)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (7)..(8)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (10)..(11)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (14)..(14)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (16)..(17)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (19)..(20)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (22)..(23)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (26)..(26)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (28)..(29)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (31)..(32)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (34)..(35)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (38)..(38)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (40)..(41)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (43)..(44)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (46)..(47)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (50)..(50)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (52)..(53)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (55)..(56)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (58)..(59)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (62)..(62)
<223>  The Proline at this position is a hydroxyproline.
<220>
<221>  SITE
<222>  (64)..(65)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (67)..(68)
<223>  The Proline at these positions is a hydroxyproline.
<220>
<221>  SITE
<222>  (70)..(71)
<223>  The Proline at these positions is a hydroxyproline.
<400>  231
Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro
1               5                   10                  15
Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro
20                  25                  30
Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser
35                  40                  45
Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro Pro Ser Pro
50                  55                  60
Pro Ser Pro Pro Ser Pro Pro Ser
65                  70
<210>  232
<211>  246
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  232
ggatcctcaa cccgggcctc accaccacca ccttctccac ctccatcacc cccaccttcg     60
cctccaccat ccccaccacc ttctccacct ccatcacccc caccttcgcc tccaccatcc    120
ccaccacctt ctccacctcc atcaccccca ccttcgcctc caccatcccc accaccttct    180
ccacctccat cacccccacc ttcgcctcca ccatcccctt ccatggcata atagagctcg    240
aattcg                                                               246
<210>  233
<211>  76
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  233
Gly Ser Ser Thr Arg Ala Ser Pro Pro Pro Pro Ser Pro Pro Pro Ser
1               5                   10                  15
Pro Pro Pro Ser Pro Pro Pro Ser Pro Pro Pro Ser Pro Pro Pro Ser
20                  25                  30
Pro Pro Pro Ser Pro Pro Pro Ser Pro Pro Pro Ser Pro Pro Pro Ser
35                  40                  45
Pro Pro Pro Ser Pro Pro Pro Ser Pro Pro Pro Ser Pro Pro Pro Ser
50                  55                  60
Pro Pro Pro Ser Pro Pro Pro Ser Pro Ser Met Ala
65                  70                  75
<210>  234
<211>  324
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  234
ggatcctcaa cccgggcctc accaccacca ccttcacctc cacccccatc tccaccacca     60
ccttcacctc cacccccatc tccaccacca ccttcacctc cacccccatc tccaccacca    120
ccttcacctc cacccccatc tccaccacca ccttcacctc cacccccatc tccaccacca    180
ccttcacctc cacccccatc tccaccacca ccttcacctc cacccccatc tccaccacca    240
ccttcacctc cacccccatc tccaccacca ccttcacctc cacccccatc tccaccacca    300
ccttccatgg cattatagag ctcg                                           324
<210>  235
<211>  104
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  235
Gly Ser Ser Thr Arg Ala Ser Pro Pro Pro Pro Ser Pro Pro Pro Pro
1               5                   10                  15
Ser Pro Pro Pro Pro Ser Pro Pro Pro Pro Ser Pro Pro Pro Pro Ser
20                  25                  30
Pro Pro Pro Pro Ser Pro Pro Pro Pro Ser Pro Pro Pro Pro Ser Pro
35                  40                  45
Pro Pro Pro Ser Pro Pro Pro Pro Ser Pro Pro Pro Pro Ser Pro Pro
50                  55                  60
Pro Pro Ser Pro Pro Pro Pro Ser Pro Pro Pro Pro Ser Pro Pro Pro
65                  70                  75                  80
Pro Ser Pro Pro Pro Pro Ser Pro Pro Pro Pro Ser Pro Pro Pro Pro
85                  90                  95
Ser Pro Pro Pro Pro Ser Met Ala
100
<210>  236
<211>  96
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  236
Gly Ser Ala Met Gly Lys Met Ala Ser Leu Phe Ala Thr Phe Leu Val
1               5                   10                  15
Val Leu Val Ser Leu Ser Leu Ala Gln Thr Thr Arg Ala Ser Pro Ser
20                  25                  30
Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser
35                  40                  45
Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser
50                  55                  60
Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser
65                  70                  75                  80
Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Ser Pro Val Ala Thr
85                  90                  95
<210>  237
<211>  38
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  237
ctctttttct ctggatccgg tctatatttt cttttagc                             38
<210>  238
<211>  37
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  238
cgggtgctgc ccgggttgtc tgacccgtga cacttgc                              37
<210>  239
<211>  426
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  239
ggatccggtc tatattttct tttagctacc atggatagaa aatttgtatt tctagtatca     60
attttgtgca ttgtagtggc aagtgtcacg ggtcagacaa cccgggccgc tccagcacct    120
gccccagccc ctgcaccagc tccagcacct gccccagccc ctgcaccagc tccagcacct    180
gccccagccc ctgcaccagc tccagcacct gccccagccc ctgcaccagc tccagcacct    240
gccccagccc ctgcaccagc tccagcacct gccccagccc ctgcaccagc tccagcacct    300
gccccagccc ctgcaccagc tccagcacct gccccagccc ctgcaccagc tccagcacct    360
gccccagccc ctgcaccagc tccagcacct gccccagccc ctgcaccagc tccagcatcc    420
atggtg                                                               426
<210>  240
<211>  103
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  240
Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro
1               5                   10                  15
Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro
20                  25                  30
Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro
35                  40                  45
Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro
50                  55                  60
Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro
65                  70                  75                  80
Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro
85                  90                  95
Ala Pro Ala Pro Ala Pro Ala
100
<210>  241
<211>  687
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  241
ggatccggtc tatattttct tttagctacc atggatagaa aatttgtatt tctagtatca     60
attttgtgca ttgtagtggc aagtgtcacg ggtcagacaa cccgggcccc aacccccaca    120
cctactccaa cgcctacccc aacccccaca cctactccaa cgcctacccc aacccccaca    180
cctactccaa cgcctacccc aacccccaca cctactccaa cgcctacccc aacccccaca    240
cctactccaa cgcctacccc aacccccaca cctactccaa cgcctacccc aacccccaca    300
cctactccaa cgcctacccc aacccccaca cctactccaa cgcctacccc aacccccaca    360
cctactccaa cgcctacccc aacccccaca cctactccaa cgcctacccc aacccccaca    420
cctactccaa cgcctacccc aacccccaca cctactccaa cgcctacccc aacccccaca    480
cctactccaa cgcctacccc aacccccaca cctactccaa cgcctacccc aacccccaca    540
cctactccaa cgcctacccc aacccccaca cctactccaa cgcctacccc aacccccaca    600
cctactccaa cgcctacccc aacccccaca cctactccaa cgcctacccc aacccccaca    660
cctactccaa cgcctacccc aaccccc                                        687
<210>  242
<211>  200
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  242
Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr
1               5                   10                  15
Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr
20                  25                  30
Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr
35                  40                  45
Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr
50                  55                  60
Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr
65                  70                  75                  80
Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr
85                  90                  95
Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr
100                 105                 110
Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr
115                 120                 125
Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr
130                 135                 140
Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr
145                 150                 155                 160
Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr
165                 170                 175
Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr Pro Thr
180                 185                 190
Pro Thr Pro Thr Pro Thr Pro Thr
195                 200
<210>  243
<211>  486
<212>  DNA
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  243
agcggccgcg gatccggtct atattttctt ttagctacca tggatagaaa atttgtattt     60
ctagtatcaa ttttgtgcat tgtagtggca agtgtcacgg gtcagacaac ccgggcccca    120
gcaactcccg ctacacctgc caccccggca accccagcaa ctcccgctac acctgccacc    180
ccggcaaccc cagcaactcc cgctacacct gccaccccgg caaccccagc aactcccgct    240
acacctgcca ccccggcaac cccagcaact cccgctacac ctgccacccc ggcaacccca    300
gcaactcccg ctacacctgc caccccggca accccagcaa ctcccgctac acctgccacc    360
ccggcaaccc cagcaactcc cgctacacct gccaccccgg caaccccagc aactcccgct    420
acacctgcca ccccggcaac cccagcaact cccgctacac ctgccacccc ggcaacctcc    480
atggtg                                                               486
<210>  244
<211>  120
<212>  PRT
<213>  Artificial Sequence
<220>
<223>  Synthetic
<400>  244
Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro
1               5                   10                  15
Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala
20                  25                  30
Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr
35                  40                  45
Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro
50                  55                  60
Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala
65                  70                  75                  80
Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr
85                  90                  95
Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro Ala Thr Pro
100                 105                 110
Ala Thr Pro Ala Thr Pro Ala Thr
115                 120