WORLD TRADE  
ORGANIZATION   
G/SPS/N/USA/2398 
15 June 2012  
 (12-3160) 
Committee on Sanitary and Phytosanitary Measures Original:   English 
  
 
NOTIFICATION 
 
1. Notifying Member:  UNITED STATES OF AMERICA 
If applicable, name of local government involved:    
2. Agency responsible:  US Environmental Protection Agency 
3. Products covered (provide tariff item numbe r(s) as specified in national schedules 
deposited with the WTO;  ICS numbers should be provided in addition, where applicable):  Multiple commodities 
4. Regions or countries likely to be affected, to the extent relevant or practicable: 
[X] All trading partners   
[ ] Specific regions or countries:    
5. Title of the notified document:  Receipt of Several Pesticide Petitions Filed for Residues 
of Pesticide Chemicals in or on Various Commodities  Language(s):  English  Number of 
pages:  4 
 http://www.gpo.gov/fdsys/pkg/FR-2012-04-04/html/2012-8095.htm  
6. Description of content:  EPA is announcing its receipt of several pesticide petitions filed 
under section 408 of the Federal Food, Drug, a nd Cosmetic Act (FFDCA), 21 U.S.C. 346a, 
requesting the establishment or modification of regulations in 40 CFR part 174 or part 180 
for residues of pesticide chemicals in or on various food commodities. 
New Tolerances 1. PP 1E7869. (EPA-HQ-OPP-2012-0048). Synge nta Crop Protection, P.O. Box 18300, 
Greensboro, NC 27409, requests to establish a to lerance in 40 CFR part 180 for residues of 
the fungicide cyprodinil, 2-pyrimidinamine, 4-cyclopropyl-6-methyl-N-phenyl-, in or on 
leafy petioles subgroup 04B at 30 parts per million (ppm). Syngenta Crop Protection, has 
developed and validated analytical methodol ogy for enforcement purposes. This method 
Syngenta Crop Protection Method AG-631B, has passed an Agency petition method validation for several commodities and is curren tly the enforcement method for cyprodinil.  
Contact: Lisa Jones, (703) 308-9424,  email address: jones.lisa@epa.gov. 
2. PP 1E7870. (EPA-HQ-OPP-2012-0047). Synge nta Crop Protection, P.O. Box 18300, 
Greensboro, NC 27409, requests to establish a to lerance in 40 CFR part 180 for residues of 
the fungicide fludioxonil, 4-(2, 2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile, in or on leafy petioles subgroup 04B at 14 ppm. Syngenta Crop Protection, has developed and validated the analytical method Syngenta Crop Protection Method AG-597B for 
enforcement purposes and has also passed an  Agency petition method validation (PMV) for 
several commodities. It is currently the en forcement method for fludioxonil and has also 
been forwarded to the Food and Drug Administration (FDA) for inclusion into Pesticide G/SPS/N/USA/2398 
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  Analytical Manual Volume II (PAM II). Contact: Lisa Jones, (703) 308-9424, email 
address: jones.lisa@epa.gov. 
3. PP 1E7924. (EPA-HQ-OPP-2012-0038). Bayer CropScience, P.O. Box 12014, 2 T. W. 
Alexander Drive, Research Triangle Park , NC 27709, requests to establish import 
tolerances in 40 CFR part 180 for residues of th e insecticide spiromesifen, 2-oxo-3-(2,4,6-
trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4 -yl 3,3-dimethylbutanoate and its enol 
metabolite; 4-hydroxy-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-2-one calculated 
as the parent compound equivalents, in or  on imported tea, dried and the processed 
commodity instant tea at 50 ppm.  Adequate analytical methodology using liquid chromatography/mass spectrometry (LC/MS/MS)  detection is available for enforcement 
purposes. Contact: Jennifer Gaines,  (703) 305-5967, email address: 
gaines.jennifer@epa.gov. 
4. PP 1E7945. (EPA-HQ-OPP-2012-0041). S yngenta Crop Protection, LLC, P.O. Box 
18300, Greensboro, NC 27419-8300, requests to establish an import tolerance in 40 CFR part 180 for residues of the fungicide azoxystrobin, methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]phenyl]-3-methoxyacrylate and the Z isomer of azoxystrobin, methyl (Z)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]pheny1]-3-
methoxyacrylate, in or on ginseng extract (red ginseng extract and ginseng extract) at 0.5 
ppm. An adequate analytical method, gas chromatography with nitrogen-phosphorus detection (GC/NPD) or in mobile phase by high performance liquid chromatography with ultra-violet detection (HPLC/UV) is available for enforcement purposes with a limit of detection that allows monitoring of food with residues at or above the levels set in these 
tolerances. Contact: Erin Malone, (703) 347- 0253, email address: malone.erin@epa.gov. 
5. PP 1E7951. (EPA-HQ-OPP-2011-1011).  Inte rregional Research Project Number 4 (IR-
4), 500 College Road East, Suite 201 W, Princeton, NJ 08540, requests to establish tolerances in 40 CFR part 180 for residues of the herbicide S-ethyl dipropylthiocarbamate 
(EPTC), including its metabolites and degradates, determined by measuring only the sum of S-ethyl dipropylthiocarbamate, S-ethyl (2-hydroxypropyl) propylcarbamothioate, S-(2-
hydroxyethyl)dipropylcarbamothioate, and S-ethyl (3-
hydroxypropyl)propylcarbamothioate, calculated as the stoichiometric equivalent of S-ethyl 
dipropylthiocarbamate, in or on fruit, citrus , group 10-10 at 0.1 ppm; sunflower subgroup 
20B at 0.08 ppm; and watermelon at 0.08 ppm . Adequate methods are available for the 
determination of EPTC and three hydroxy me tabolites in crops, including watermelon. 
EPTC is analyzed by extraction of the macera ted samples with toluene with subsequent 
quantification using GC/NPD. The three hydr oxy metabolites are extracted from macerated 
samples with a mixture of acetone and water. The acetone is dispelled and the aqueous fraction is digested with acid. The hydrolyzed metabolites are then extracted with a mixture 
of hexane and ether, and the extract is pur ified through a solid phase extraction cartridge. 
The residues are then derivatized and quantifie d using a GC equipped with a mass-selective 
detector (MSD). Contact: Sidney Jacks on, (703) 305-7610, email address: 
jackson.sidney@epa.gov. 
6. PP 1E7957. (EPA-HQ-OPP-2012-0010). Interregional Research Project Number 4 (IR-
4), 500 College Road East, Suite 201 W, Princeton, NJ 08540, requests to establish tolerances in 40 CFR part 180 for residues of the herbicide quinclorac, 3,7-dichloro-8-
quinolinecarboxylic acid, including its me tabolites and degradates determined by 
measuring only quinclorac, in or on rhubarb  at 0.4 ppm; and berry, low growing, except 
strawberry, subgroup 13-07H at 1.1 ppm. Adequa te analytical methods, utilizing GC with 
electron capture detection (GC/ECD), are ava ilable to enforce the tolerance expression on 
plant (BASF Method A8902) and animal (BASF Method 268/1) commodities. Both 
methods have undergone successful Agency me thod validation trials, and have been 
submitted to the FDA for publication in PAM II as the tolerance enforcement methods.  G/SPS/N/USA/2398 
 Page 3 
 
 
  Contact: Sidney Jackson, (703) 305-7610, email address: jackson.sidney@epa.gov. 
7. PP 1E7958. (EPA-HQ-OPP-2012-0107). Interregional Research Project Number 4 (IR-
4), 500 College Road East, Suite 201 W, Princeton, NJ 08540, requests to establish tolerances in 40 CFR part 180 for residues of the insecticide spirotetramat, cis-3-(2,5-
dimethlyphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl-ethyl carbonate and its metabolites BYI 08330-enol cis-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-
azaspiro[4.5]dec-3-en-2-one, BYI 08330-keto hydroxy cis-3-(2,5-dimethylphenyl)-3-
hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione, BYI 08330-enol-Glc cis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4. 5]dec-3-en-4-yl beta-D-glucopyranoside, 
and BYI 08330-mono-hydroxy cis-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one, calculated as spirotetrama t equivalents, in or on taro, leaves at 9 
ppm; watercress at 1.5 ppm; pomegranate at 0.5 ppm; banana at 4 ppm; vegetable, bulb, 
group 3-07 at 0.6 ppm; berry, low growing, except strawberry, subgroup 13-07H at 0.3 
ppm; bushberry, subgroup 13-07B at 3 ppm; artic hoke, globe at 2 ppm; vegetable, fruiting, 
group 8-10 at 2.5 ppm; fruit, pome, group 11-10 at 0.7 ppm; fruit, citrus, group 10-10 at 0.6 
ppm; pineapple at 0.3 ppm; pineapple, process residue at 0.36 ppm; coffee, green beans at 0.2 ppm; and coffee, roast beans at 0.32 ppm. Spirotetramat residues are quantified in raw 
agricultural commodities by HPLC/trip le stage quadrupole mass spectrometry 
(HPLC/MS/MS) using the stable isotopically labeled analytes as internal standards. Contact: Laura Nollen, (703) 305-7390, email address: nollen.laura@epa.gov. 
8. PP 1F7845. (EPA-HQ-OPP-2011-0458). Bayer CropScience, 2 T. W. Alexander Drive, 
P.O. Box 12014, Research Triangle Park, NC 27709, requests to establish a tolerance in 40 CFR part 180 for residues of the fungicide tr ifloxystrobin, benzeneacetic acid, (E,E)-
[alpha]-(methoxyimino)-2-[[[[1-[3-(trifluoromethyl) phenyl] ethylidene] 
amino]oxy]methyl]-methyl ester, and the free form of its acid metabolite CGA-321113, (E,E)-methoxyimino-[2-[1-(3-trifluoromethyl-phenyl)-ethylideneaminooxymethyl]-phenyl]acetic acid, in or on artichoke, globe at  1.0 ppm. A practical analytical method for 
detecting and measuring levels of trifloxystro bin, in or on raw agricultural commodities is 
based on crop specific cleanup procedures and determination by GC/NPD. A newer 
analytical method is available by LC/MS/MS with electrospray interface, operated in the 
positive ion mode. Contact: Tawanda Mai gnan, (703) 308-8050, email address: 
maignan.tawanda@epa.gov. 
9. PP 1F7954. (EPA-HQ-OPP-2012-0029). E. I. DuPont de Nemours and Company, 
DuPont Crop Protection, 1007 Market Street, Wilmington, DE 19898, requests to establish 
a tolerance in 40 CFR part 180 for residues of the chlorantraniliprole, 3-bromo-N-[4-
chloro-2-methyl-6-[(methylamino)-carbon yl]phenyl]-1-(3-chloro-2-pyridinyl)-1H-
pyrazole-5-carboxamide, in or on oilseed, rapeseed, subgroup 20A at 2.0 ppm; oilseed, sunflower, subgroup 20B at 2.0 ppm; oilseed, cottonseed, subgroup 20C at 0.3 ppm; soybean, aspirated grain fractions at 300 ppm ; vegetable, legume, group 6 at 2.0 ppm; 
vegetable, foliage of legume, group 7 at 30 ppm; and forage, ve getable, foliage of legume, 
group 7 at 90 ppm. An analytical residue method has been submitted to EPA which permits determination of trace residues of the pa rent compound on various food and feed 
commodities. Contact: Jennifer Urbanski , (703) 347-0156, email address: 
urbanski.jennifer@epa.gov. 
Amended Tolerances 
1. PP 1E7951. (EPA-HQ-OPP-2011-1011). Interregional Research Project Number 4 (IR-
4), 500 College Road East, Suite 201 W, Princeton, NJ 08540, requests to amend the tolerances in 40 CFR 180.117 for residues of th e herbicide S -ethyl dipropylthiocarbamate 
(EPTC), including its metabolites and degradates, determined by measuring only the sum of S -ethyl dipropylthiocarbamate, S -ethyl (2-hydroxypropyl) propylcarbamothioate, S -(2-G/SPS/N/USA/2398 
Page 4  
 
  hydroxyethyl)dipropylcarbamothioate, and S -ethyl (3-
hydroxypropyl)propylcarbamothioate, calculated as the stoichiometric equivalent of S -
ethyl dipropylthiocarbamate, by removing th e following established tolerances: Fruit, 
citrus, group 10 at 0.1 ppm; safflower, seed at  0.08 ppm; and sunflower, seed at 0.08 ppm, 
as these commodities are included in updated crop groups or subgroups  listed under ``New 
Tolerances'' for PP 1E7951. Contact: Sidne y Jackson, (703) 305-7610, email address: 
jackson.sidney@epa.gov. 
2. PP 1E7958. (EPA-HQ-OPP-2012-0107). Interregional Research Project Number 4 (IR-
4), 500 College Road East, Suite 201 W, Princeton, NJ 08540, requests to amend 40 CFR 180.641 for residues of the insecticide spirot etramat, cis-3-(2,5-dimethlyphenyl)-8-
methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl-ethyl carbonate and its metabolites BYI 08330-enol cis-3-(2,5-dimethylphenyl)-4-h ydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-
one, BYI 08330-ketohydroxy cis-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-
azaspiro[4.5]decane-2,4-dione, BYI 08330-enol-Glc cis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-y l beta-D-glucopyranoside, and BYI 08330-
mono-hydroxy cis-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one, calculated as spirotetramat equivalents, by  removing the established tolerances: Onion, 
bulb, subgroup 3A-07 at 0.30 ppm; fruit, citrus, group 10 at 0.60 ppm; fruit, pome, group 
11 at 0.70 ppm; okra at 2.5 ppm; and vegetable,  fruiting, group 8 at 2.5 ppm, as they will be 
superseded by inclusion in updated cr op groups or subgroups listed under ``New 
Tolerances''. Contact: Laura Nollen, (703) 305- 7390, email address: nollen.laura@epa.gov. 
New Tolerance Exemptions 1. PP 1E7912. (EPA-HQ-OPP-2012-0014). ICR, Inc., 1330 Dillon Heights Ave, 
Catonsville, MD on behalf of Triton Systems,  Inc., 200 Turnpike Road, Chelmsford, MA 
01824, requests to establish an exemption from the requirement of a tolerance for residues 
of 1,2-Ethanediamine, N1-(2-aminoethyl )-, polymer with 2,4-diisocyanato-1-
methylbenzene, with number average molecula r weight greater than 10,000 daltons, (CAS 
No. 35297-61-1) under 40 CFR 180.960 when used as a pesticide inert ingredient 
microencapsulation in pesticide formulations . The petitioner believes no analytical method 
is needed because this information is genera lly not required when all criteria for polymer 
exemption under 40 CFR 723.250 are met. Contact: Anthony Britten, (703) 308-8179, 
email address: britten.anthony@epa.gov. 
2. PP 1E7938. (EPA-HQ-OPP-2012-0043). Honeyw ell International, Inc., 101 Columbia 
Road, Morristown, NJ 07962-1053, requests to establish an exemption from the 
requirement of a tolerance for residues of trans-1,3,3,3-tetrafluoroprop-1-ene, (CAS No. 
29118-24-9) under 40 CFR 180.910, 180.930, and 180.940 when used as a pesticide inert ingredient propellant in pesticide formula tions. The petitioner believes no analytical 
method is needed because this is a petiti on for exemption from the requirement of a 
tolerance. Contact: Lisa Austin, (703) 305- 7894, email address: austin.lisa@epa.gov. 
3. PP 1F7960. (EPA-HQ-OPP-2012-0152). Ene rfab, Inc., 4955 Spring Grove Avenue, 
Cincinnati, OH 45232, requests to establish an exemption from the requirement of a tolerance for residues of the antimicrobial gaseous chlorine dioxide, on tomato. EPA 
Method 300, Ion Chromatography, was used fo r measuring chlorite and chlorate residues 
rinsed from surface of produce treated with ch lorine dioxide gas. Contact: Jaclyn Carl, 
(703) 347-0213, email address: carl.jaclyn@epa.gov. 
Amended Tolerance Exemption PP 1F7857. (EPA-HQ-OPP-2012-0109). Syngenta Seeds, Inc., Field Crops NAFTA, P.O. 
Box 12257, 3054 E. Cornwallis Road, Research  Triangle Park, NC 27709-2257, requests to 
amend an exemption from the requirement of a tolerance in 40 CFR 174.532 for residues of  G/SPS/N/USA/2398 
 Page 5 
 
 
  the plant-incorporated protectant (PIP), Bacillu s thuringiensis eCry3.1Ab protein in corn, in 
or on the food and feed commodities of corn; corn, field; corn, sweet; and corn, pop. The 
petitioner believes no analytical method is  needed because an exemption from the 
requirement of a tolerance is being sought. Ho wever, in response to an Agency request, the 
Petitioner has submitted an immunoassay method for determination of eCry3.1Ab protein 
in corn tissues. Contact: Mike Mende lsohn, (703) 308-871 5, email address: 
mendelsohn.mike@epa.gov. 
7. Objective and rationale:  [X] food safety, [ ] animal health, [ ] plant protection, 
[ ] protect humans from animal/plant pest or disease, [ ] protect territory from other 
damage from pests.    
8. Is there a relevant international stan dard?  If so, identify the standard:  
[ ] Codex Alimentarius Commission (e.g.  title or serial number of Codex standard 
or related text)   
[ ] World Organization for Animal Health (OIE) (e.g. Terrestrial or Aquatic 
Animal Health Code, chapter number)    
[ ] International Plant Protection Convention (e.g. ISPM number)    
[X] None Does this proposed regulation conform to the relevant international standard?   
 [ ] Yes   [ ] No 
 If no, describe, whenever possible, how and why it deviates from the 
international standard:    
9. Other relevant documents and language (s) in which these are available:      
10. Proposed date of adoption (dd/mm/yy) :  Not applicable 
Proposed date of publication (dd/mm/yy) :  Not applicable 
11. Proposed date of entry into force:  [ ] Six months from date of publication , and/or  
(dd/mm/yy) :  4 May 2012 
[X] Trade facilitating measure   
12. Final date for comments:  [ ] Sixty days from the date of circulation of the notification 
and/or (dd/mm/yy) :  4 May 2012 
Agency or authority designated to handl e comments:  [ ] National Notification 
Authority, [ ] National Enquiry Point.  Address, fax number and e-mail address (if 
available) of other body:  multiple, please see notice 
13. Texts available from:  [X] National Notification Authority, [ ] National Enquiry Point.  
Address, fax number and e-mail address (if available) of other body:   United States 
SPS National Notification Authority, USDA Fore ign Agricultural Service, International 
Regulations and Standards Division (IRSD), Stop 1014, Washington D.C. 20250;  Tel:  +(1 
202) 720 1301;  Fax:  +(1 202) 720 0433;  E-mail:  us.s psenquirypoint@fas.usda.gov