Notice of Modification to the  List of 
Permitted Sweeteners  to Enable the 
Use of Steviol Glycosides from 
Saccharomyces cerevisiae  Y63348  in a 
Variety of Foods  
Notice of Modification  – Lists of Permitted Food 
Additives  
Reference Number: NOM/ADM-0151 
September  1, 2020  
  
Notice of Modification to the List of Permitted Sweeteners  to Enable the Use of Steviol Glycosides from Saccharomyces cerevisiae  
Y63348  in a Variety of Foods  – Reference Number: NOM/ADM -0151| 2 
 Summary  
Food additives are regulated in Canada under Marketing Authorizations  (MAs) issued by the Minister of 
Health and the Food and Drug Regulations  (Regulations) .  Approved food additives and their permitted 
conditions of use are set out in the Lists of Pe rmitted Food Additives  that are incorporated by reference in 
the MAs and published on the Canada.ca website.  A petitioner can request that Health Canada approve a 
new additive or a new condition of use for an already approved food additive by filing a foo d additive 
submission with the Department's Food Directorate.  Health Canada uses this premarket approval process to 
determine whether the scientific data support the safety of food additives when used under specified 
conditions in foods sold in Canada.  
Health Canada’s Food Directorate received a food additive submission seeking approval for the use of  steviol 
glycosides from Saccharomyces cerevisiae  Y63348 as a sweetener  in the foods where steviol glycosides from 
other sources is currently permitted and at  the same maximum levels of use.  
Steviol glycosides1 from Stevia rebaudiana  Bertoni, S. cerevisiae  CD15380 and S. cerevisiae  CD15407  is 
already permitted for use in Canada as a sweetener in a variety of standardized and unstandardized foods.  
The results of the Food Directorate’s evaluation of available scientific data support the safety of steviol 
glycosides from S. cerevisiae  Y63348  for the same uses as are already permitted for steviol glycosides from 
these other sources .  Therefore, Health Canada has modified the  List of Permitted Sweeteners  to enable  
these uses of steviol glycosides from S. cerevisiae  Y63348  by adding the name of this source to  column 1 of 
item no. S.1.2  of this List, as shown below.  
 
Modification to the List of Permitted Sweeteners   
Item 
No. Column 1  
Additive  Column 2  
Permitted in or Upon  Column 3  
Maximum Level of Use and Other 
Conditions  
S.1.2  Steviol glycosides 
from:  
Stevia rebaudiana  
Bertoni; . . . 
Saccharomyces 
cerevisiae  Y63348  (1) Table -top sweeteners  (1) Good Manufacturing Practice  
. . . . . . 
(11) (naming the flavour) Milk; 
(naming the flavour) Partly 
skimmed milk; (naming the 
flavour) Partly skimmed milk with 
added milk solids; (naming the 
flavour) Skim milk; (naming the 
flavour) Skim milk with added milk 
solids  (11) 0.02% (calculated as steviol 
equivalents)  
Rationale  
Health Canada’s Food Directorate completed a premarket safety assessment of steviol glycosides from 
S. cerevisiae  Y63348  for use as a sweetener .  The assessment concluded that information re lated to 
chemistry, microbiolog y, molecular biology, nutrition and  toxicology supports the safety of steviol glycosides 
                                                             
1 When referring to the name of the additive , the term “steviol glycosides” is used in the singular  form . Notice of Modification to the List of Permitted Sweeteners  to Enable the Use of Steviol Glycosides from Saccharomyces cerevisiae  
Y63348  in a Variety of Foods  – Reference Number: NOM/ADM -0151| 3 
 from S. cerevisiae  Y63348  for its requested uses.  Therefore, the Department has enabled the requested uses 
of steviol glycosides from S. cerevisiae  Y63348  by modifying the List of Permitted Sweeteners  as shown  in the 
above table.    
Other Relevant Information  
The Food and Drug Regulations  require that food additives such as steviol glycosides that do not have 
food -grade specifications set out in Part B of the Regulations meet the food -grade specifications set out in 
the most recent edition of the  Food Chemicals Codex  or the Combined Compen dium of Food Additive 
Specifications .  The Food Chemicals Codex  is a compendium of standards for purity and identity for food 
ingredients, including food additives, published by the United States Pharmacopeial Convention. The 
Combined Compendium of Food Ad ditive Specifications , which contains specifications prepared by the Joint 
FAO/WHO Expert Committee on Food Additives (JECFA), is published by the Food and Agriculture 
Orga nization  (FAO)  of the United Nations.   
Implementation and Enforcement  
The above modi fication came into force September  1, 2020 , the day it was published in  the List of Permitted 
Sweeteners .  
The Canadian Food Inspection Agency is responsible for the enforcement of the Food and Drugs Act and its 
associated regulations with respect to foods.   
Contact Information  
Health Canada's Food Directorate is committed to reviewing any new scientific infor mation on the safety in 
use of any food additive, including steviol glycosides from S. cerevisiae  Y63348 .  Anyone wishing to submit 
new scientific information on th e use of this additive or to submit any inquiries may do so in writing, by 
regular mail or e lectronically.  If you wish to contact the Food Directorate electro nically, please use the words 
"Steviol glycosides (NOM -0151)" in the subject line of your e -mail.   
Bureau of Chemical Safety, Food Directorate  
251 Sir Frederick Banting Driveway  
Tunney’s Pasture, PL: 2202C  
Ottawa, Ontario K1A 0K9  
E-mail: hc.bcs -bipc.sc@canada.ca