. /.   WORLD TRADE  
ORGANIZATION  G/SPS/N/USA/1715 
2 October 2007  
 (07-4183) 
Committee on Sanitary a nd Phytosanitary Measures Original:   English 
  
 
 
NOTIFICATION 
 
1. Member to Agreement notifying:  UNITED STATES
  
If applicable, name of local government involved:     
2. Agency responsible:  Environmental Protection Agency (EPA) 
3. Products covered (provide tariff item numb er(s) as specified in national schedules 
deposited with the WTO; ICS numbers should be provided in addition, where applicable):  DDVP is registered to control insect pests on agricultural sites; commercial, 
institutional and industrial sites; and for domest ic use in and around homes (i.e., resin strips). 
DDVP is used preplant in mushroom houses, and postharvest in storage areas for bulk, 
packaged and bagged raw and processed agricultural commodities, food 
manufacturing/processing plants, animal prem ises, and non-food areas of food-handling 
establishments. It is also registered for direct dermal treatment of cattle and poultry, and swine, sheep, and goats. 
4. Regions or countries likely to be affected, to the extent relevant or practicable :  Any 
US trade partners 
5. Title, language and number of pages of the notified document:  NOTICE: Dichlorvos 
(DDVP); Proposed Determinati on to Terminate Special Review (available in English, 
5 pages) 
6. Description of content:  This notice sets forth EPA's Propo sed Determination to Terminate 
Special Review for the pesticide Dichlorvos  (DDVP). On 24 February 1988, the Agency 
published a Notice of Special Review (PD 1) of pesticide products containing DDVP based 
on concerns for cancer, cholinestera se inhibition, a nd liver effects.  
On 28 September 1995, the Agency published a Notice of Preliminar y Determination to 
Cancel Certain Registrations and a Draft Notice of Intent to Ca ncel (PD 2/3).  In the 1995 PD 
2/3, the Agency determined that exposure to  dichlorvos from the registered uses posed 
carcinogenic risks of concern as well as risk s of concern for cholinesterase inhibition. 
However, with respect to liver effects, the Agency determined that this endpoint was no 
longer of regulatory concern.  Since the initi ation of Special Review  and publication of the 
PD 2/3, additional data have become available.  Based in part on these data, the Agency has 
changed its assessment of some of the risks associated with DDVP, and modified the terms 
and conditions of DDVP registrations, accordingl y.  Moreover, during the recently-concluded 
reregistration process for DDVP, EPA conducted an intensive and public review of whether 
DDVP registrations meet the FIFRA standard fo r registration, culminating in the Agency's 
2006 Interim Reregistration Eligibility Decision (IRED) for DDVP. Through the 
reregistration processes the Agency resolved  remaining concerns regarding cancer and 
cholinesterase effects.  G/SPS/N/USA/1715 
Page 2  
 
  Accordingly, EPA has revised its assessment of DDVP since the time when the PD 1 and the 
PD 2/3 were published. Based on the IRED, re quested label amendments, and the voluntary 
cancellation of uses by the registrant pursuant  to federal law, EPA has determined that the 
risks that were the basis of the Special Review  are no longer of concern and, therefore, the 
Agency is proposing to terminate the Special Review of DDVP.  To the extent that the 
Agency further revises its assessment of DDVP,  it will do so outside of the Special Review 
context. 
7. Objective and rationale:  [ X ] food safety, [ X ] animal health,  [ X ] plant protection, 
[ X ] protect humans from animal/plant pest or disease,  [   ] protect territory from other damage from pests    
8. International standard, guideline or recommendation:  
[   ] Codex Alimentarius Commission, [   ] World Organization for Animal Health 
(OIE), [   ] International Plant Protection Convention, [ X ] None  
If an international standard, guideline or recommendation exists, give the appropriate 
reference and briefly identify deviations:    
9. Relevant documents and language (s) in which these are available:   F e d e r a l  R e g i s t e r :   
26 September 2007 (Volume 72, Nu mber 186)Notices Page 54658-54662 
http://www.epa.gov/fedrgstr/EPA-P EST/2007/Septembe r/Day-26/p18861.htm  
10. Proposed date of adoption:  N/A 
11. Proposed date of entry into force:  This is a notice of availability which may or may not 
result in further regulatory action. 
12. Final date for comments:  Comments must be received on or before 26 October 2007, and 
may be identified by docke t number EPA-HQ-OPP-2006-0396. 
Agency or authority designated to handle comments:  [   ] National notification 
authority, [ X ] National enquiry point, or  address, fax number and E-mail address (if 
available) of other body: 
Registration Division ,(7505P), Office of Pe sticide Programs, Environmental Protection 
Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460-0001 
13. Texts available from:  [ X ] National notificati on authority, [   ] Na tional enquiry point, 
or address, fax number and E-mail address (if available) of other body: 
United States SPS National Notification Aut hority, USDA Foreign Agricultural Service, 
International Regulations and Standards Division (IRSD), Stop 1027, Washington D.C. 
20250;  Tel:  +(1 202) 720-1301;  Fa x:  +(1 202) 690-0677;  E-mail:  
us.spsenquirypoint@fas.usda.gov