COMMI SSION IMPLEMENTING REGUL ATION (EU) 2018/248 
of 15 Febr uary 2018 
concer ning the author isation of 2,3-diethylp yrazine, 2,5 or 6-metho xy-3-methy lpyrazine, 2-acetyl- 
3-ethylp yrazine, 2,3-diethyl-5-meth ylpyrazine, 2-(sec-butyl)-3-metho xypy razine, 2-ethyl-3-metho xy­
pyrazine, 5,6,7,8-tetrahydroquino xaline, 2-ethy lpyrazine and 5-methylq uino xaline as feed additiv es 
for all animal species 
(Text with EEA relevance) 
THE EUR OPEAN COMMISSION, 
Having regar d to the Treaty on the Functioning of the European Union, 
Having regar d to Regulation (EC) No 1831/2003 of the European Parliament and of the Council of 22 September 2003 
on additives for use in animal nutr ition (1), and in particular Article 9(2) thereof, 
Whereas: 
(1)  Regulation (EC) No 1831/2003 provi des for the author isation of additives for use in animal nutr ition and for the 
grounds and procedures for granting such author isation. Article 10 of that Regulation provides for the 
re-evaluation of additives author ised pursuant to Council Directive 70/524/EEC (2). 
(2)  The substances 2,3-diethylp yrazine, 2,5 or 6-metho xy-3-methylp yrazine, 2-acetyl-3-eth ylpyrazine, 2,3-diethy l-5- 
meth ylpyrazine, 2-(sec-butyl)-3-metho xypyrazine, 2-ethyl-3-metho xypyrazine, 5,6,7,8-tetrah ydroquino xaline, 
2-ethy lpyrazine and 5-methylquino xaline (‘substances concer ned’) were author ised without a time limit by 
Directive 70/524/EEC as feed additives for all animal species. Those substances were subsequently entered in the 
Regist er of feed additives as existing products, in accordance with Article 10(1) of Regulation (EC) 
No 1831/2003. 
(3)  In accordance with Article 10(2) of Regulation (EC) No 1831/2003 in conjunction with Article 7 thereof, an 
application was submitted for the re-evaluation of the substances concer ned as feed additives for all animal 
species. The applicant request ed those additives be classified in the additive catego ry ‘sensor y additives ’. That 
application was accompan ied by the particulars and documents required under Article 7(3) of Regulation (EC) 
No 1831/2003. 
(4)  The European Food Safety Auth ority (‘the Author ity’) concluded in its opinion of 6 December 2016 (3) that, 
under the proposed conditions of use the substances concer ned do not have adverse effects on animal health, 
human health or the environment. These substances increase the food smell or palatability . The Author ity has 
concluded that since the substances concer ned are used in food as flavouri ngs and their function in feed is 
essentially the same as in food, no further demonstration of effic acy is necessar y. Theref ore, that conclusion can 
be extrapolated for feed. The applicant withdrew the application for use of the substances concer ned in wate r for 
drinking. 
(5)  The Auth ority further note d that for the substances concer ned hazards for the skin, eye contact and respirato ry 
exposure are recognised. Most substances are classifie d as irritating to the respirato ry system. Consequently , 
appropr iate prote ctive measures should be taken. The Author ity does not consider that there is a need for 
specific requirements of post-market monitori ng. It also verified the repor t on the method of analysis of the feed 
additives in feed submitt ed by the Reference Laboratory set up by Regulation (EC) No 1831/2003. 
(6)  The assessment of the substances concer ned shows that the conditions for author isation, as provided for in 
Article 5 of Regulation (EC) No 1831/2003, are satisfied. According ly, the use of those substances should be 
author ised as specified in the Annex to this Regulation. 
(7)  The applicant proposed use levels for the substances concer ned to the Author ity. Having regard to that proposal, 
the Author ity considered that certain use levels are safe (‘levels considered by the Author ity’). For the purpose of 
official controls along the food chain, certain labelling requirements should be provid ed for. In particular , where 
the use levels exceed the levels considered by the Author ity, it is appropr iate to require that the label of 
premixtures and the labelling of feed mater ials and compo und feed containing the substances concer ned include 
certain information including referen ce to the levels considered by the Author ity. 23.2.2018 L 53/120 Official Jour nal of the European Union EN     
(1)OJ L 268, 18.10.2003, p. 29. 
(2)Council Directive 70/524/EEC of 23 November 1970 concer ning additives in feedingstuffs (OJ L 270, 14.12.1970, p. 1). 
(3)EFSA Journal 2016;15(2):4671. (8)  The fact that the use of the substances concer ned in water for drinking is not author ised does not preclude their 
use in compo und feed which is administ ered via water . 
(9) Since safety reasons do not require the immediate application of the modifi cations to the conditions of author is­
ation for the substances concer ned, it is appropr iate to allow a transitional period for inter ested parties to 
prepare themselves to meet the new requirements resulting from the author isation. 
(10)  The measures provi ded for in this Regulation are in accordance with the opinion of the Standing Committee on 
Plants, Animals, Food and Feed, 
HAS ADOPTED THIS REGUL ATION: 
Article 1 
Author isation 
The substances specifi ed in the Annex, belonging to the additive catego ry ‘sensor y additives ’ and to the functional group 
‘flavouri ng compounds’, are author ised as feed additives in animal nutr ition subject to the conditions laid down in that 
Annex. 
Article 2 
Transitional measures 
1. The substances specifi ed in the Annex and premixtures containing those substances, whic h are produced and 
labelled before 15 Sept ember 2018 in accordance with the rules applicable before 15 March 2018 may continue to be 
placed on the mark et and used until the existing stoc ks are exhausted. 
2. Feed mat erials and compo und feed containing the substances as specified in the Annex which are produced and 
labelled before 15 March 2019 in accordance with the rules applicable before 15 March 2018 may continue to be 
placed on the mark et and used until the existing stoc ks are exhausted if they are intende d for food-producing animals. 
3. Feed mat erials and compo und feed containing the substances as specified in the Annex which are produced and 
labelled before 15 March 2020 in accordance with the rules applicable before 15 March 2018 may continue to be 
placed on the mark et and used until the existing stocks are exhaust ed if they are intende d for non-f ood-producing 
animals. 
Article 3 
Entr y into force 
This Regulation shall enter into force on the twentieth day followi ng that of its publication in the Official Journal of the 
European Union. 
This Regulation shall be binding in its entirety and directly applicable in all Member State s. 
Done at Brussels, 15 Febr uary 2018. 
For the Commission 
The President 
Jean-Claude JUNCK ER  23.2.2018 L 53/121 Official Jour nal of the European Union EN     ANNEX 
Identifica ­
tion 
number of 
the 
additive Name of 
the holder 
of author ­
isation Additive Composition, chemical formula, 
descr iption, analytical method Species or 
categ ory of 
animal Maximum 
age Minimum 
content Maximum 
conten t 
Other provisions End of 
period of 
author is­
ation mg of active substance/kg 
of complet e feed ingstuff 
with a moisture content of 
12 % 
Categor y: Sensor y additiv es. Functional group: Flavour ing compounds 
2b14005 — 2,3- 
Dieth yl­
pyrazine Additive composition 
2,3-Diethyl pyrazine 
Char acter isation of the activ e sub­
stance 
2,3-Diethyl pyrazine 
Produced by chemical synthesis 
Purity: min. 97 % assa y 
Chemical formula: C8H12N2 
CAS number: 15707-24-1 
FLAVIS No: 14.005 
Method of analysis (1) 
For the determination of 2,3- 
dieth ylpyrazine in the feed addi ­
tive and in feed flavouring 
premixtures: 
Gas chromat ography mass spec ­
trometr y with retention time lock­
ing GC-MS-RT L. All animal 
species — — — 1.  The additive shall be incor porated into the 
feed in the form of a premixture. 
2.  In the directions for use of the additive 
and premixtures, the storag e and stability 
conditions shall be indicated . 
3.  On the label of the additive the following 
shall be indicated : 
‘Recommended maximum content of the 
active substance of compl ete feedingstuff 
with a moisture cont ent of 12 %: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies’. 
4.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
on the label of the premixture where the 
use levels suggest ed on the label of the 
premixture would result in exceeding the 
levels referred to in point 3. 
5.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
in the labelling of feed mater ials and com ­
pound feedingstuffs where the content of 
the active substance in the complet e 
feedingstuff with a moisture conte nt of 
12 % exceed s: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies  15.3.2028 23.2.2018 L 53/122 Official Jour nal of the European Union EN     Identifica ­
tion 
number of 
the 
additive Name of 
the holder 
of author ­
isation Additive Composition, chemical formula, 
descr iption, analytical method Species or 
categ ory of 
animal Maximum 
age Minimum 
content Maximum 
conten t 
Other provisions End of 
period of 
author is­
ation mg of active substance/kg 
of complet e feed ingstuff 
with a moisture content of 
12 % 
6.  For users of the additive and premixtures, 
feed business operat ors shall establish op­
erational procedures and organisational 
measures to address poten tial risks by in­
halation, dermal contact or eyes contact. 
Where those risks cannot be eliminated or 
reduced to a minimum by such procedures 
and measures, the additive and premix ­
tures shall be used with personal prot ective 
equipment, including breathing protection, 
safety glasses and gloves.           
2b14025 — 2,5 or 6- 
Metho xy- 
3-methyl ­
pyrazine Additive composition 
2,5 or 6-Metho xy-3-meth ylpyra­
zine 
Char acter isation of the activ e sub­
stance 
2,5 or 6-Metho xy-3-meth ylpyra­
zine 
Produced by chemical synthesis 
Purity: min. 97 % assa y 
Chemical formula: C6H8ON2 
CAS number: 63450-30-6 
FLAVIS No: 14.025 
Method of analysis (1) 
For the deter mination of 2,5 or 
6-metho xy-3-meth ylpyrazine in 
the feed additive and in feed fla­
vouring premixtures: 
Gas chromat ography mass spec ­
trometr y with retention time lock­
ing GC-MS-RT L. All animal 
species — — — 1.  The additive shall be incor porated into the 
feed in the form of a premixture. 
2.  In the directions for use of the additive 
and premixtures, the storag e and stability 
conditions shall be indicated . 
3.  On the label of the additive the following 
shall be indicated : 
‘Recommended maximum content of the 
active substance of compl ete feedingstuff 
with a moisture cont ent of 12 %: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies’. 
4.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
on the label of the premixture where the 
use levels suggest ed on the label of the 
premixture would result in exceeding the 
levels referred to in point 3.  15.3.2028 23.2.2018 L 53/123 Official Jour nal of the European Union EN     Identifica ­
tion 
number of 
the 
additive Name of 
the holder 
of author ­
isation Additive Composition, chemical formula, 
descr iption, analytical method Species or 
categ ory of 
animal Maximum 
age Minimum 
content Maximum 
conten t 
Other provisions End of 
period of 
author is­
ation mg of active substance/kg 
of complet e feed ingstuff 
with a moisture content of 
12 % 
5.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
in the labelling of feed mater ials and com ­
pound feedingstuffs where the content of 
the active substance in the complet e 
feedingstuff with a moisture conte nt of 
12 % exceed s: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies 
6.  For users of the additive and premixtures, 
feed business operat ors shall establish op­
erational procedures and organisational 
measures to address poten tial risks by in­
halation, dermal contact or eyes contact. 
Where those risks cannot be eliminated or 
reduced to a minimum by such procedures 
and measures, the additive and premix ­
tures shall be used with personal prot ective 
equipment, including breathing protection, 
safety glasses and gloves.           
2b14049 — 2-Acetyl- 
3-ethy lpyr­
azine Additive composition 
2-Acetyl-3-eth ylpyrazine 
Char acter isation of the activ e sub­
stance 
2-Acetyl-3-eth ylpyrazine 
Produced by chemical synthesis 
Purity: min. 98 % assa y 
Chemical formula: C8H10ON2 
CAS number: 32974-92-8 
FLAVIS No: 14.049  All animal 
species — — — 1.  The additive shall be incor porated into the 
feed in the form of a premixture. 
2.  In the directions for use of the additive 
and premixtures, the storag e and stability 
conditions shall be indicated . 
3.  On the label of the additive the following 
shall be indicated : 
‘Recommended maximum content of the 
active substance of compl ete feedingstuff 
with a moisture cont ent of 12 %: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies’.  15.3.2028 23.2.2018 L 53/124 Official Jour nal of the European Union EN     Identifica ­
tion 
number of 
the 
additive Name of 
the holder 
of author ­
isation Additive Composition, chemical formula, 
descr iption, analytical method Species or 
categ ory of 
animal Maximum 
age Minimum 
content Maximum 
conten t 
Other provisions End of 
period of 
author is­
ation mg of active substance/kg 
of complet e feed ingstuff 
with a moisture content of 
12 % 
Method of analysis (1) 
For the determination of 2-acetyl- 
3-ethy lpyrazine in the feed addi ­
tive and in feed flavouring 
premixtures: 
Gas chromat ography mass spec ­
trometr y with retention time lock­
ing GC-MS-RT L. 4.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
on the label of the premixture where the 
use levels suggest ed on the label of the 
premixture would result in exceeding the 
levels referred to in point 3. 
5.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
in the labelling of feed mater ials and com ­
pound feedingstuffs where the content of 
the active substance in the complet e 
feedingstuff with a moisture conte nt of 
12 % exceed s: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies 
6.  For users of the additive and premixtures, 
feed business operat ors shall establish op­
erational procedures and organisational 
measures to address poten tial risks by in­
halation, dermal contact or eyes contact. 
Where those risks cannot be eliminated or 
reduced to a minimum by such procedures 
and measures, the additive and premix ­
tures shall be used with personal prot ective 
equipment, including breathing protection, 
safety glasses and gloves.           
2b14056 — 2,3- 
Dieth yl-5- 
meth ylpyr­
azine Additive composition 
2,3-Diethyl -5-methy lpyrazine  All animal 
species — — — 1.  The additive shall be incor porated into the 
feed in the form of a premixture. 
2.  In the directions for use of the additive 
and premixtures, the storag e and stability 
conditions shall be indicated .  15.3.2028 23.2.2018 L 53/125 Official Jour nal of the European Union EN     Identifica ­
tion 
number of 
the 
additive Name of 
the holder 
of author ­
isation Additive Composition, chemical formula, 
descr iption, analytical method Species or 
categ ory of 
animal Maximum 
age Minimum 
content Maximum 
conten t 
Other provisions End of 
period of 
author is­
ation mg of active substance/kg 
of complet e feed ingstuff 
with a moisture content of 
12 % 
Char acter isation of the activ e sub­
stance 
2,3-Diethyl -5-methy lpyrazine 
Produced by chemical synthesis 
Purity: min. 98 % assa y 
Chemical formula: C9H14N2 
CAS number: 18138-04-0 
FLAVIS No: 14.056 
Method of analysis (1) 
For the determination of 2,3- 
dieth yl-5-methylp yrazine alcohol 
in the feed additive and in feed 
flavouring premixtures: 
Gas chromat ography mass spec ­
trometr y with retention time lock­
ing GC-MS-RT L. 3.  On the label of the additive the following 
shall be indicated : 
‘Recommended maximum content of the 
active substance of compl ete feedingstuff 
with a moisture cont ent of 12 %: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies’. 
4.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
on the label of the premixture where the 
use levels suggest ed on the label of the 
premixture would result in exceeding the 
levels referred to in point 3. 
5.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
in the labelling of feed mater ials and com ­
pound feedingstuffs where the content of 
the active substance in the complet e 
feedingstuff with a moisture conte nt of 
12 % exceed s: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies  23.2.2018 L 53/126 Official Jour nal of the European Union EN     Identifica ­
tion 
number of 
the 
additive Name of 
the holder 
of author ­
isation Additive Composition, chemical formula, 
descr iption, analytical method Species or 
categ ory of 
animal Maximum 
age Minimum 
content Maximum 
conten t 
Other provisions End of 
period of 
author is­
ation mg of active substance/kg 
of complet e feed ingstuff 
with a moisture content of 
12 % 
6.  For users of the additive and premixtures, 
feed business operat ors shall establish op­
erational procedures and organisational 
measures to address poten tial risks by in­
halation, dermal contact or eyes contact. 
Where those risks cannot be eliminated or 
reduced to a minimum by such procedures 
and measures, the additive and premix ­
tures shall be used with personal prot ective 
equipment, including breathing protection, 
safety glasses and gloves.           
2b14062 — 2-(sec-Bu ­
tyl)-3- 
metho xy­
pyrazine Additive composition 
2-(sec-Butyl)-3-metho xypyrazine 
Char acter isation of the activ e sub­
stance 
2-(sec-Butyl)-3-metho xypyrazine 
Produced by chemical synthesis 
Purity: min. 99 % assa y 
Chemical formula: C9H14ON2 
CAS number: 24168-70-5 
FLAVIS No: 14.062 
Method of analysis (1) 
For the deter mination of 2-(sec- 
butyl)-3-metho xypyrazine in the 
feed additive and in feed flavour­
ing premixtures: 
Gas chromat ography mass spec ­
trometr y with retention time lock­
ing GC-MS-RT L. All animal 
species — — — 1.  The additive shall be incor porated into the 
feed in the form of a premixture. 
2.  In the directions for use of the additive 
and premixtures, the storag e and stability 
conditions shall be indicated . 
3.  On the label of the additive the following 
shall be indicated : 
‘Recommended maximum content of the 
active substance of compl ete feedingstuff 
with a moisture cont ent of 12 %: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies’. 
4.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
on the label of the premixture where the 
use levels suggest ed on the label of the 
premixture would result in exceeding the 
levels referred to in point 3.  15.3.2028 23.2.2018 L 53/127 Official Jour nal of the European Union EN     Identifica ­
tion 
number of 
the 
additive Name of 
the holder 
of author ­
isation Additive Composition, chemical formula, 
descr iption, analytical method Species or 
categ ory of 
animal Maximum 
age Minimum 
content Maximum 
conten t 
Other provisions End of 
period of 
author is­
ation mg of active substance/kg 
of complet e feed ingstuff 
with a moisture content of 
12 % 
5.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
in the labelling of feed mater ials and com ­
pound feedingstuffs where the content of 
the active substance in the complet e 
feedingstuff with a moisture conte nt of 
12 % exceed s: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies 
6.  For users of the additive and premixtures, 
feed business operat ors shall establish op­
erational procedures and organisational 
measures to address poten tial risks by in­
halation, dermal contact or eyes contact. 
Where those risks cannot be eliminated or 
reduced to a minimum by such procedures 
and measures, the additive and premix ­
tures shall be used with personal prot ective 
equipment, including breathing protection, 
safety glasses and gloves.           
2b14112 — 2-Ethyl-3- 
metho xy­
pyrazine Additive composition 
2-Ethy l-3-metho xypyrazine 
Char acter isation of the activ e sub­
stance 
2-Ethy l-3-metho xypyrazine 
Produced by chemical synthesis 
Purity: min. 99 % assa y 
Chemical formula: C7H10N2O 
CAS number: 25680-58-4 
FLAVIS No: 14.112  All animal 
species — — — 1.  The additive shall be incor porated into the 
feed in the form of a premixture. 
2.  In the directions for use of the additive 
and premixtures, the storag e and stability 
conditions shall be indicated . 
3.  On the label of the additive the following 
shall be indicated : 
‘Recommended maximum content of the 
active substance of compl ete feedingstuff 
with a moisture cont ent of 12 %: 
—  0,1 mg/kg for pigs and poultr y 
—0,5 mg/kg for other species and cat­
egor ies’.  15.3.2028 23.2.2018 L 53/128 Official Jour nal of the European Union EN     Identifica ­
tion 
number of 
the 
additive Name of 
the holder 
of author ­
isation Additive Composition, chemical formula, 
descr iption, analytical method Species or 
categ ory of 
animal Maximum 
age Minimum 
content Maximum 
conten t 
Other provisions End of 
period of 
author is­
ation mg of active substance/kg 
of complet e feed ingstuff 
with a moisture content of 
12 % 
Method of analysis (1) 
For the determination of 2-ethy l- 
3-metho xypyrazine in the feed ad­
ditive and in feed flavouring 
premixtures: 
Gas chromat ography mass spec ­
trometr y with retention time lock­
ing GC-MS-RT L. 4.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
on the label of the premixture where the 
use levels suggest ed on the label of the 
premixture would result in exceeding the 
levels referred to in point 3. 
5.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
in the labelling of feed mater ials and com ­
pound feedingstuffs where the content of 
the active substance in the complet e 
feedingstuff with a moisture conte nt of 
12 % exceed s: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies 
6.  For users of the additive and premixtures, 
feed business operat ors shall establish op­
erational procedures and organisational 
measures to address poten tial risks by in­
halation, dermal contact or eyes contact. 
Where those risks cannot be eliminated or 
reduced to a minimum by such procedures 
and measures, the additive and premix ­
tures shall be used with personal prot ective 
equipment, including breathing protection, 
safety glasses and gloves.           
2b14015 — 5,6,7,8- 
Tetrahy ­
droqui ­
noxaline Additive composition 
5,6,7,8- Tetrahy droquino xaline  All animal 
species — — — 1.  The additive shall be incor porated into the 
feed in the form of a premixture. 
2.  In the directions for use of the additive 
and premixtures, the storag e and stability 
conditions shall be indicated .  15.3.2028 23.2.2018 L 53/129 Official Jour nal of the European Union EN     Identifica ­
tion 
number of 
the 
additive Name of 
the holder 
of author ­
isation Additive Composition, chemical formula, 
descr iption, analytical method Species or 
categ ory of 
animal Maximum 
age Minimum 
content Maximum 
conten t 
Other provisions End of 
period of 
author is­
ation mg of active substance/kg 
of complet e feed ingstuff 
with a moisture content of 
12 % 
Char acter isation of the activ e sub­
stance 
5,6,7,8- Tetrahy droquino xaline 
Produced by chemical synthesis 
Purity: min. 98 % assa y 
Chemical formula: C8H10N2 
CAS number: 34413-35-9 
FLAVIS No: 14.015 
Method of analysis (1) 
For the determination of 5,6,7,8- 
tetrahydroquino xaline in the feed 
additive and in feed flavouring 
premixtures: 
Gas chromat ography mass spec ­
trometr y with retention time lock­
ing GC-MS-RT L. 3.  On the label of the additive the following 
shall be indicated : 
‘Recommended maximum content of the 
active substance of compl ete feedingstuff 
with a moisture cont ent of 12 %: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies’. 
4.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
on the label of the premixture where the 
use levels suggest ed on the label of the 
premixture would result in exceeding the 
levels referred to in point 3. 
5.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
in the labelling of feed mater ials and com ­
pound feedingstuffs where the content of 
the active substance in the complet e 
feedingstuff with a moisture conte nt of 
12 % exceed s: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies  23.2.2018 L 53/130 Official Jour nal of the European Union EN     Identifica ­
tion 
number of 
the 
additive Name of 
the holder 
of author ­
isation Additive Composition, chemical formula, 
descr iption, analytical method Species or 
categ ory of 
animal Maximum 
age Minimum 
content Maximum 
conten t 
Other provisions End of 
period of 
author is­
ation mg of active substance/kg 
of complet e feed ingstuff 
with a moisture content of 
12 % 
6.  For users of the additive and premixtures, 
feed business operat ors shall establish op­
erational procedures and organisational 
measures to address poten tial risks by in­
halation, dermal contact or eyes contact. 
Where those risks cannot be eliminated or 
reduced to a minimum by such procedures 
and measures, the additive and premix ­
tures shall be used with personal prot ective 
equipment, including breathing protection, 
safety glasses and gloves.           
2b14022 — 2-Ethyl ­
pyrazine Additive composition 
2-Ethy lpyrazine 
Char acter isation of the activ e sub­
stance 
2-Ethy lpyrazine 
Produced by chemical synthesis 
Purity: min. 98 % assa y 
Chemical formula: C6H8N2 
CAS number: 13925-00-3 
FLAVIS No: 14.022 
Method of analysis (1) 
For the determination of 2-ethy l­
pyrazine in the feed additive and 
in feed flavouring premixtures: 
Gas chromat ography mass spec ­
trometr y with retention time lock­
ing GC-MS-RT L. All animal 
species — — — 1.  The additive shall be incor porated into the 
feed in the form of a premixture. 
2.  In the directions for use of the additive 
and premixtures, the storag e and stability 
conditions shall be indicated . 
3.  On the label of the additive the following 
shall be indicated : 
‘Recommended maximum content of the 
active substance of compl ete feedingstuff 
with a moisture cont ent of 12 %: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies’. 
4.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
on the label of the premixture where the 
use levels suggest ed on the label of the 
premixture would result in exceeding the 
levels referred to in point 3.  15.3.2028 23.2.2018 L 53/131 Official Jour nal of the European Union EN     Identifica ­
tion 
number of 
the 
additive Name of 
the holder 
of author ­
isation Additive Composition, chemical formula, 
descr iption, analytical method Species or 
categ ory of 
animal Maximum 
age Minimum 
content Maximum 
conten t 
Other provisions End of 
period of 
author is­
ation mg of active substance/kg 
of complet e feed ingstuff 
with a moisture content of 
12 % 
5.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
in the labelling of feed mater ials and com ­
pound feedingstuffs where the content of 
the active substance in the complet e 
feedingstuff with a moisture conte nt of 
12 % exceed s: 
—  0,1 mg/kg for pigs and poultr y. 
—0,5 mg/kg for other species and cat­
egor ies 
6.  For users of the additive and premixtures, 
feed business operat ors shall establish op­
erational procedures and organisational 
measures to address poten tial risks by in­
halation, dermal contact or eyes contact. 
Where those risks cannot be eliminated or 
reduced to a minimum by such procedures 
and measures, the additive and premix ­
tures shall be used with personal prot ective 
equipment, including breathing protection, 
safety glasses and gloves.           
2b14028 — 5-Methy l­
quino xa­
line Additive composition 
5-Methy lquino xaline 
Char acter isation of the activ e sub­
stance 
5-Methy lquino xaline 
Produced by chemical synthesis 
Purity: min. 98 % assa y 
Chemical formula: C9H8N2 
CAS number: 13708-12-8 
FLAVIS No: 14.028  All animal 
species — — — 1.  The additive shall be incor porated into the 
feed in the form of a premixture. 
2.  In the directions for use of the additive 
and premixtures, the storag e and stability 
conditions shall be indicated . 
3.  On the label of the additive the following 
shall be indicated : 
‘Recommended maximum content of the 
active substance of compl ete feedingstuff 
with a moisture cont ent of 12 %: 
—  0,05 mg/kg for pigs and poultr y 
—0,08 mg/kg for other species and cat­
egor ies.’  15.3.2028 23.2.2018 L 53/132 Official Jour nal of the European Union EN     Identifica ­
tion 
number of 
the 
additive Name of 
the holder 
of author ­
isation Additive Composition, chemical formula, 
descr iption, analytical method Species or 
categ ory of 
animal Maximum 
age Minimum 
content Maximum 
conten t 
Other provisions End of 
period of 
author is­
ation mg of active substance/kg 
of complet e feed ingstuff 
with a moisture content of 
12 % 
Method of analysis (1) 
For the deter mination of 5- 
meth ylquino xaline in the feed 
additive and in feed flavouring 
premixtures: 
Gas chromat ography mass spec ­
trometr y with retention time lock­
ing GC-MS-RT L. 4.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
on the label of the premixture where the 
use levels suggest ed on the label of the 
premixture would result in exceeding the 
levels referred to in point 3. 
5.  The functional group, the identif ication 
number , the name and the added amount 
of the active substance shall be indicated 
in the labelling of feed mater ials and com ­
pound feedingstuffs where the content of 
the active substance in the complet e 
feedingstuff with a moisture conte nt of 
12 % exceed s: 
—  0,05 mg/kg for pigs and poultr y. 
—0,08 mg/kg for other species and cat­
egor ies 
6.  For users of the additive and premixtures, 
feed business operat ors shall establish op­
erational procedures and organisational 
measures to address poten tial risks by in­
halation, dermal contact or eyes contact. 
Where those risks cannot be eliminated or 
reduced to a minimum by such procedures 
and measures, the additive and premix ­
tures shall be used with personal prot ective 
equipment, including breathing protection, 
safety glasses and gloves.           
(1)  Details of the analytical methods are available at the following address of the Reference Laborato ry: https://ec.europa.eu/jrc/en/eurl/feed-addi tives/evaluation-repor ts   23.2.2018 L 53/133 Official Jour nal of the European Union EN