EN    EN  
 EUROPEAN 
COMMISSION  
Brussels, XXX   
[…](2012) XXX  draft 
  
COMMISSION REGULATION (EU) No …/.. 
of XXX  
amending, for the purposes of its adaptation to technica l and scientific progress, 
Regulation (EC) No 1272/200 8 of the European Parliame nt and of the Council on 
classification, labelling and packaging of substances and mixtures 
(Text with EEA relevance) 
  
EN 2   EN COMMISSION REGULATION (EU) No …/.. 
of XXX  
amending, for the purposes of its adaptation  to technical and scientific progress, 
Regulation (EC) No 1272/2008 of the Europe an Parliament and of the Council on 
classification, labelling and packagi ng of substances and mixtures 
(Text with EEA relevance) 
THE EUROPEAN COMMISSION, 
Having regard to the Treaty on the Functioning of the European Union, Having regard to Regulation (EC) No 1272/2008 of the European Parliament and of the 
Council of 16 December 2008 on classification, labe lling and packaging of substances and 
mixtures, amending and repealing Directiv es 67/548/EEC and 1999/45/EC, and amending 
Regulation (EC) No 1907/2006
1, and in particular Ar ticle 37(5) thereof, 
Whereas: (1) Part 3 of Annex VI to Regulation (EC) No 1272/2008 contains two lists of harmonised 
classification and labelling of hazardous substances. Table 3.1 lists the harmonised 
classification and labelling of hazardous subs tances based on the criteria set out in 
Parts 2 to 5 of Annex I to Regulati on (EC) No 1272/2008. Table 3.2 lists the 
harmonised classification and labelling of hazardous substances based on the criteria 
set out in Annex VI to  Council Directive 67/548/ EEC of 27 June 1967 on the 
approximation of laws, regulations and ad ministrative provisions relating to the 
classification, packaging and la belling of dangerous substances
2. Those two lists need 
to be amended to include updated classifica tions for substances already subject to 
those harmonised classifications and to include new harmonised classifications.  
(2) The Committee for Risk Assessment (RAC) of the European Chemicals Agency 
(ECHA) has issued opinions on proposals for harmonised classification and labelling of substances which had been submitted to ECHA pursuant to Article 37 of Regulation 
(EC) No 1272/2008. Based on those opinions, as  well as on the comments received 
from the parties concerned, it is appropriate  to amend Annex VI to Regulation (EC) 
No 1272/2008 in order to harmonise the cl assification and labe lling of certain 
substances. 
(3) The harmonised classifications set out in Part 3 of Annex VI to Regulation (EC) No 
1272/2008, as amended by this Regulation, shoul d not apply immediately, as a certain 
period of time will be necessary to allo w operators to adapt the labelling and 
packaging of substances and mixtures to the new classifications and to sell existing 
stocks. In addition, a certain period of tim e will be necessary to allow operators to 
comply with the registra tion obligations resulting from the new harmonised 
classifications for substances classified as carcinogenic, muta genic or toxic to 
reproduction, categories 1A and 1B (Table 3.1) and categories 1 and 2 (Table 3.2), or 
                                                
 
1 OJ L 353, 31.12.2008, p. 1.  
2 OJ 196, 16.8.1967, p. 1.   
EN 3   EN as very toxic to aquatic organisms which may cause long term effects in the aquatic 
environment, in particular with those se t out in Article 23 of  Regulation (EC) No 
1907/2006 of the European Parliament a nd of the Council of 18 December 2006 
concerning the Registration, Evaluation, Aut horisation and Restriction of Chemicals 
(REACH), establishing a European Ch emicals Agency, amending Directive 
1999/45/EC and repealing Council Regula tion (EEC) No 793/93 and Commission 
Regulation (EC) No 1488/94 as well as  Council Directive 76/769/EEC and 
Commission Directives 91/155/EEC , 93/67/EEC, 93/105/EC and 2000/21/EC3.  
(4) With regard to the substance 'pitch, coal  tar, high-temp.; pitch' (EC Number: 
266-028-2), an extended period of time will be necessary to allow operators to comply 
with the obligations resulting from the new harmonised classification for substances classified as very toxic to aquatic organisms which may cause  long term effects in the 
aquatic environment, in particular with thos e set out in Article 6 of Council Directive 
96/82/EC of 9 December 1996 on the contro l of major-accident hazards involving 
dangerous substances
4, in Article 7 of Directive 2012/18/EU of the European 
Parliament and of the Council of 4 July 2012 on the control of ma jor-accident hazards 
involving dangerous substa nces, amending and subsequently repealing Council 
Directive 96/82/EC5, and in Article 3 and Annex II I of Directive 2008/68/EC of the 
European Parliament and of the Council of 24 September 2008 on the inland transport 
of dangerous goods6. Therefore, a longer tr ansition time should be foreseen before the 
harmonised classification has to be applied.  
(5) With regard to the substan ce gallium arsenide (EC Numb er: 215-114-8), the RAC is in 
the process of adopting a new opinion for th e hazard class 'toxicity to reproduction'. 
Therefore, this hazard class should not be  included in Annex VI to Regulation (EC) 
No 1272/2008 until that opinion is finalised.   
(6) With regard to the substance polyhex amethylene biguanide hydrochloride PHMB 
(CAS number 27083-27-80 or 32289-58-0), ne w scientific data has been made 
available for the hazard class 'acute toxicity (inhalation)', which suggests that the classification for this hazard class as recommended in the RAC opinion, which is 
based on older data, might not be appropriate . Therefore, this hazard class should not 
be included in Annex VI to Regulati on (EC) No 1272/2008 until RAC has had the 
opportunity to deliver an opinion on the ne w information, while all other hazard 
classes covered by the earlier RA C opinion should be included.  
(7) In line with the transition al provisions of Regulati on (EC) No 1272/2008 which allow 
the application of the new pr ovisions at an earlier stage on  a voluntary basis, suppliers 
should have the possibility of applying the ha rmonised classifications  set out in Part 3 
of Annex VI to Regulation (EC) No 1272/ 2008, as amended by this Regulation, and of 
adapting the labelling and packaging accordin gly on a voluntary basis before the dates 
by which the harmonised classifications will become mandatory. 
(8) The measures provided for in this Regulati on are in accordance with the opinion of the 
Committee established under Article 133 of Regulation (EC) No 1907/2006, 
                                                
 
3 OJ L 396, 30.12.2006, p. 1. 
4 OJ L 10, 14.1.1997, p. 13. 
5 OJ L 197, 24.7.2012, p. 1.  
6 OJ L 260, 30.9.2008, p. 13.  
EN 4   EN HAS ADOPTED THIS REGULATION: 
Article 1 
Part 3 of Annex VI to Regulation (EC) No 1272/2008 is amended as follows: 
(1) Table 3.1 is amended as follows: 
(a) The entries set out in Annex VI to  Regulation (EC) No 1272/2008 corresponding 
to the entries set out in Annex I to this Regulation are replaced by the entries set out in Annex I to this Regulation; 
(b) The entries set out in Annex II to this Regulation are inserted  in accordance with 
the order of the entries set out in Table 3.1. 
(2) Table 3.2 is amended as follows: 
(a) The entries set out in Annex VI to  Regulation (EC) No 1272/2008 corresponding 
to the entries set out in Annex III to th is Regulation are replaced by the entries 
set out in in Annex III to this Regulation; 
(b) The entries set out in Annex IV to this  Regulation are inserted in accordance with 
the order of the entries set out in Table 3.2. 
Article 2 
1. This Regulation shall enter into force on the twentieth day following that of its 
publication in the Official Journal of the European Union . 
2. Article 1 shall apply from 1 January 2015 for all entries except for the entry 'pitch, 
coal tar, high-temp.; pitch' (EC Number  266-028-2), for which Article 1 shall apply 
from 1 April 2016.  
3. The harmonised classifications set out in Pa rt 3 of Annex VI to  Regulation (EC) No 
1272/2008, as amended by this Regulation, may be applied before the dates referred 
to in Article 2(2).  
This Regulation shall be binding in  its entirety and directly applicable in all Member States. 
Done at Brussels,  
 For the Commission 
 The President  José Manuel BARROSO  
EN 5   EN ANNEX I  
Classification Labelling  
Index No  
International Chemical Identification  
EC No  
CAS No 
Hazard Class 
and Category Code(s) Hazard 
statement Code(s) Pictogram, 
Signal Word 
Code(s) Hazard 
statement Code(s) Suppl. 
Hazard statement 
Code(s) Specific Conc. 
Limits, 
M - Factors Notes 
015-004-00-8 aluminium phosphide 244-088-0 20859-73-8 Water-react. 1 
Acute Tox. 2 
Acute Tox. 3 Acute Tox. 1 
Aquatic Acute 1 H260 
H300 
H311 H330 
H400 GHS02 
GHS06 
GHS09 Dgr H260 
H300 
H311 H330 
H400 EUH029 
EUH032 M =100  
015-005-00-3 magnesium phosphide; 
trimagnesium 
diphosphide 235-023-7 12057-74-8 Water-react. 1 
Acute Tox. 2 
Acute Tox. 3 
Acute Tox. 1 Aquatic Acute 1 H260 
H300 
H311 
H330 H400 GHS02 
GHS06 
GHS09 
Dgr H260 
H300 
H311 
H330 H400 EUH029 
EUH032 M =100  
015-123-00-5 fenamiphos (ISO); 
ethyl-4-methylthio- m-tolyl isopropyl 
phosphoramidate 244-848-1 22224-92-6 Acute Tox. 2 
Acute Tox. 2 
Acute Tox. 2 
Eye Irrit. 2 Aquatic Acute 1 
Aquatic 
Chronic 1 H300 
H310 
H330 
H319 H400 
H410 GHS06 
GHS09 
Dgr H300 
H310 
H330 
H319  
H410  M =100 
M =100   
030-012-00-1 aluminium-magnesium-zinc-carbonate-
hydroxide 423-570-6 169314-88-9 Aquatic 
Chronic 4 H413  H413    
602-006-00-4 chloroform; 
trichloromethane 200-663-8 67-66-3 Carc. 2 
Repr. 2 Acute Tox. 3 
Acute Tox. 4 
STOT RE 1 Eye Irrit. 2 Skin Irrit. 2 H351 
H361d H331 
H302 
H372 H319 H315 GHS06 
GHS08 Dgr 
 H351 
H361d H331 
H302 
H372 H319 H315    
603-097-00-3 1,1',1''-nitrilotripropan-2-ol;  
triisopropanolamine 
 204-528-4 122-20-3 Eye Irrit. 2 H319 GHS07 
Wng H319     
EN 6   EN 605-008-00-3 acrolein; 
prop-2-enal; acrylaldehyde 203-453-4 107-02-8 Flam. Liq. 2 
Acute Tox. 1 Acute Tox. 2 
Acute Tox. 3 
Skin Corr. 1 Aquatic Acute 1 
Aquatic 
Chronic 1 H225 
H330 H300 
H311 
H314 H400 
H410 GHS02 
GHS06 GHS05 
GHS09 
Dgr H225 
H330 H300 
H311 
H314  
H410 EUH071 Skin Corr. 1; 
H314: C ≥  
0.1 % 
 
M =100 
M =1  D 
607-023-00-0 vinyl acet ate 203-545-4 108-05- 4 Flam. Liq. 2 
Carc. 2 Acute Tox. 4 
STOT SE 3 
 H225 
H351 H332 
H335 GHS02 
GHS08 GHS07 
Dgr H225 
H351 H332 
H335   D 
607-613-00-8 reaction mass of;  
succinic acid 
monopersuccinic acid dipersuccinic acid 
monomethyl ester of succinic acid 
monomethyl ester of persuccinic acid dimethyl succinate 
glutaric acid 
monoperglutaric acid diperglutaric acid 
monomethyl ester of glutaric acid 
monomethyl ester of perglutaric acid dimethyl glutarate 
adipic acid 
monoperadipic acid diperadipic acid 
monomethyl ester of adipic acid 
monomethyl ester of peradipic acid dimethyl adipate 
hydrogen peroxide 
methanol water 
 
 432-790-1  Acute Tox. 4* 
Acute Tox. 4* 
Acute Tox. 4* Skin Corr. 1B 
STOT SE 2 H332 
H312 
H302 H314 
H371 (eyes) GHS07 
GHS05 
GHS08 Dgr H332 
H312 
H302 H314 
H371 (eyes)    
609-003-00-7 Nitrobenzene 202-716-0 98-95-3 Carc. 2. 
Repr. 1B Acute Tox. 3 Acute Tox. 3 
Acute Tox. 3 
STOT RE 1 Aquatic 
Chronic 3 H351 
H360F H301 H331 
H311 
H372 (blood)H412 GHS06 
GHS08 Dgr H351 
H360F H301 H331 
H311 
H372 (blood)H412     
EN 7   EN 612-120-00-6 aclonifen (ISO); 
2-chloro-6-nitro- 3-phenoxyaniline 277-704-1 74070-46-5 Carc. 2 
Skin Sens. 1A Aquatic Acute 1 
Aquatic 
Chronic 1 H351 
H317 H400 
H410 GHS08 
GHS07 GHS09 
Wng H351 
H317  
H410  M =100  
M =10   
613-175-00-9 epoxiconazole (ISO); 
(2RS,3SR)-3-(2-chlorophenyl)-2-(4-fluorophenyl)-[( 
1H-1,2,4-triazol-1-yl)methyl]oxirane 406-850-2 133855-98-8 Carc. 2 
Repr. 1B Aquatic 
Chronic 2 H351 
H360Df H411 GHS08 
GHS09 Dgr H351 
H360Df H411    
616-200-00-1 reaction mass  of N,N'-ethane-1,2-
diylbis(hexanamide) and 12-hydroxy-N-[2-
[(1-oxyhexyl)amino]et hyl]octadecanamide 
and N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan amide) 
 432-430-3 
  Aquatic  
Chronic 4 H413  H413    
648-055-00-5 pitch, coal tar, high-temp.;  
pitch; 
[The residue from the distillation of high temperature coal tar. A black solid with an 
approximate softening point from 30 °C to 
180 °C (86 °F to 356 °F). Composed primarily of a complex mixture of three or 
more membered condensed ring aromatic 
hydrocarbons.]  266-028-2 65996-93-2 Carc. 1A 
Muta. 1B 
Repr. 1B Aquatic Acute 1 
Aquatic 
Chronic 1 H350 
H340 
H360FD H400 
H410 GHS08 
GHS09 
Dgr H350 
H340 
H360FD  
H410  M =1000 
M =1000   
649-330-00-2 naphtha (petroleum), 
hydrodesulphurized 
heavy;  
Low boiling point hydrogen treated naphtha;[A complex combination of hydrocarbons 
obtained from a catalytic 
hydrodesulfurization process. It consists of hydrocarbons having carbon numbers 
predominantly in the range of C7 through 
C12 and boiling in the range of approximately 90 °C to 230 °C (194 °F to 
446 °F).] 
 265-185-4 64742-82-1 Carc. 1B 
Muta. 1B 
STOT RE 1 
Asp. Tox. 1 H350 
H340 
H372 (central
nervous system) 
H304 GHS08 
Dgr H350 
H340 
H372 (central
nervous system) 
H304   P 
649-405-00-X solvent naphtha (petroleum), medium aliph.; 
Straight run kerosine; [A complex combination of hydrocarbons obtained from the distilla tion of crude oil or 
natural gasoline. It cons ists predominantly of 265-191-7 64742-88-7 STOT RE 1 
Asp. Tox. 1 H372 (central
nervous system) H304 GHS08 
Dgr H372 (central
nervous system) H304     
EN 8   EN  saturated hydrocarbons having carbon 
numbers predominantly in the range of C9 through C12 and boiling in the range of 
approximately 140 °C to 220 °C (284 °F to 
428 °F).]  
649-345-00-4 stoddard solvent; 
Low boiling point 
naphtha — unspecified; 
[A colourless, refine d petroleum distillate 
that is free from rancid or objectionable 
odours and that boils in a range of 
approximately 148,8 °C to 204,4 °C (300  °F to 400 °F).] 232-489-3 8052-41-3 Carc. 1B 
Muta. 1B 
STOT RE 1 
Asp. Tox. 1 H350 
H340 
H372 (central
nervous system) 
H304 GHS08 
Dgr H350 
H340 
H372 (central
nervous system) 
H304   P  
EN 9   EN  
ANNEX II  
Classification Labelling  
Index No  
International Chemical Identification  
EC No  
CAS No 
Hazard Class 
and Category Code(s) Hazard 
statement Code(s) Pictogram, 
Signal Word 
Code(s) Hazard 
statement Code(s) Suppl. 
Hazard statement 
Code(s) Specific Conc. 
Limits, 
M - Factors Notes 
031-001-00-4 gallium ar senide 215-114-8 1303- 00-0 Carc. 1B 
STOT RE 1 H350 
H372 
(respiratory and 
haematopoieti
c systems) GHS08 
Dgr 
 H350 
H372 
(respiratory and 
haematopoieti
c systems)    
050-025-00-6 trichloromethylstanna ne  213-608-8 993-16-8 Repr. 2 
 H361d 
 GHS08 
Wng H361d    
050-026-00-1 2-ethylhexyl 10-ethyl-4-[[2-[(2-
ethylhexyl)oxy]-2-oxoethyl]thio]-4-methyl-
7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate  260-828-5 57583-34-3 Repr. 2 H361d GHS08 
Wng H361d    
050-027-00-7 2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-
oxa-3,5-dithia-4-stannatetradecanoate 239-622-4 15571-58-1 Repr. 1B H360D GHS08 
Dgr H360D    
601-087-00-3 2,4,4-trimethylpentene 246-690-9 25167-70-8 Flam. Liq. 2 
Asp. Tox. 1 STOT SE 3 H225 
H304 H336 GHS02 
GHS07 GHS08 
Dgr H225 
H304 H336 
   D 
606-145-00-1 sulcotrione (ISO); 
2-[2-chloro-4-
(methylsulfonyl)benzoyl]cyclohexane-1,3-dione 
  99105-77-8  Repr. 2 
STOT RE 2  
Skin Sens. 1A Aquatic Acute 1 
Aquatic 
Chronic 1 H361d 
H373 
(kidneys) H317 
H400 
H410 GHS08 
GHS07 
GHS09 Wng 
 H361d  
H373 
(kidneys) H317 
 
H410  M =1 
M =10  
607-699-00-7 bifenthrin (ISO); 
(2-methylbiphenyl-3-yl)methyl rel-(1R,3R)-
3-[(1 Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-
yl]-2,2-dimethylcy clopropanecarboxylate 
  82657-04-3 Carc. 2 
Acute Tox. 3 Acute Tox. 2 
STOT RE 1 
Skin Sens. 1B Aquatic Acute 1 H351 
H331 H300 
H372 
(nervous system) GHS06 
GHS08 GHS09 
Dgr H351 
H331 H300 
H372 
(nervous system)  M =10000  
M =100000    
EN 10   EN Aquatic 
Chronic 1 H317 
H400 H410 H317 
 H410 
607-703-00-7 ammoniumpentadeca- 
fluorooctanoate 223-320-4 3825-26-1 Carc. 2 
Repr. 1B 
Lact. 
Acute Tox. 4 Acute Tox. 4 
STOT RE 1  
Eye dam.1  H351 
H360D 
H362 
H332 H302 
H372 (liver) 
H318 GHS08 
GHS07 
GHS05 
Dgr H351 
H360D 
H362 
H332 H302 
H372 (liver) 
H318    
607-704-00-2 perfluorooctanoic 
acid 206-397-9 335-67-1 Carc. 2 
Repr. 1B Lact. 
Acute Tox. 4 
Acute Tox. 4 STOT RE 1  
Eye Dam. 1 
 H351 
H360D H362 
H332 
H302 H372 (liver) 
H318 GHS08 
GHS07 GHS05 
Dgr H351 
H360D H362 
H332 
H302 H372 (liver) 
H318    
607-700-00-0 i ndoxacarb (ISO); 
methyl (4a S)-7-chloro-2-
{(methoxycarbonyl)[4-
(trifluoromethoxy)phenyl]carbamoyl}-2,5-
dihydroindeno[1,2- e][1,3,4]oxadiazine-
4a(3H)-carboxylate [1] 
 
reaction mass of (S)- Indoxacarb and (R)- Indoxacarb 75:25; 
methyl 7-chloro-2-{(methoxycarbonyl)[4-
(trifluoromethoxy)phenyl]carbamoyl}-2,5-dihydroindeno[1,2- e][1,3,4]oxadiazine-
4a(3H)-carboxylate [2] 
  173584-44-6 [1]
  
 
  
144171-61-9 [2] Acute Tox. 3 
Acute Tox. 4 STOT RE 1 
Skin Sens. 1B 
Aquatic Acute 1 Aquatic 
Chronic 1 
 H301 
H332 H372 
H317 
H400 H410 GHS06 
GHS08 GHS09 
Dgr H301 
H332 H372 
H317 
 H410  M =1 
M =1   
607-702-00-1 dihexyl phthalate 201-55 9-5 84-75-3 Repr. 1B H360FD GHS08 
Dgr  H360FD    
612-282-00-8 octadecylamine 204-695-3 124-30-1 Asp. Tox. 1 
STOT RE 2 
Skin Irrit. 2 
Eye Dam. 1 Aquatic Acute 1 Aquatic 
Chronic 1 H304 
H373 (gastro-
intestinal 
tract, liver, immune system) 
H315 
H318 GHS05 
GHS08 
GHS09 
Dgr H304 
H373 (gastro-
intestinal 
tract, liver, immune system) 
H315 
H318  M =10 
M =10 
   
EN 11   EN H400 
H410   
H410  
612-283-00-3 (Z)-octadec-9-enylamine 204-015-5 112-90-3 Acute Tox. 4 
Asp Tox. 1 
STOT SE 3 
STOT RE 2 Skin Corr. 1B 
Aquatic Acute 1 
Aquatic Chronic 1 H302 
H304 
H335 
H373 (gastro-intestinal 
tract, liver, 
immune system) 
H314 
H400 H410 GHS05 
GHS07 
GHS08 
GHS09 Dgr 
 H302 
H304 
H335 
H373 (gastro-intestinal 
tract, liver, 
immune system) 
H314 
 H410   M =10  
M =10  
  
612-284-00-9 amines, hydrogenated tallow alkyl 262-976-6 61788-45-2 Asp Tox. 1 
STOT RE 2 
Skin Irrit. 2 
Eye Dam. 1 Aquatic Acute 1 
Aquatic 
Chronic 1  H304 
H373 
(gastro-
intestinal tract, liver, 
immune 
system) H315 
H318 
H400 H410 GHS08 
GHS05 
GHS09 
Dgr  H304 
H373 
(gastro-
intestinal tract, liver, 
immune 
system) H315 
H318 
 H410 
  M =10 
M =10   
612-285-00-4 amines, coco alkyl 262-977-1 61788-46-3 Acute Tox. 4 
Asp. Tox. 1 
STOT SE3 STOT RE 2 
Skin Corr. 1B 
Aquatic Acute 1 Aquatic 
Chronic 1 H302 
H304 
H335 H373 (gastro-
intestinal 
tract, liver, immune 
system) 
H314 H400 
H410 GHS05 
GHS07 
GHS08 GHS09 
Dgr 
 H302  
H304 
H335 H373 (gastro-
intestinal 
tract, liver, immune 
system) 
H314  
H410  M =10  
M =10  
612-286-00-X amines, tallow alkyl 263-125-1 61790-33-8 Acute Tox. 4 
Asp. Tox. 1 
STOT RE 2  
Skin Corr. 1B Aquatic Acute 1 
Aquatic 
Chronic 1 H302 
H304 
H373 (gastro-
intestinal tract, liver, 
immune 
system) GHS05 
GHS07 
GHS08 
GHS09 Dgr 
 H302 
H304 
H373 (gastro-
intestinal tract, liver, 
immune 
system)  M =10  
M =10  
   
EN 12   EN  H314 
H400 H410 H314 
  
H410 
 
616-206-00-4 flufenoxuron (ISO); 
1-(4-(2-cloro- α,α,α-p-trifluorotolyloxy)-2-
fluorophenyl)-3-(2,6-difluorobenzolyl)urea 417-680-3 101463-69-8 Lact. 
Aquatic Acute 1 Aquatic 
Chronic 1 
 H362 
H400 H410 GHS09 
Wng H362 
 H410  M =10000  
M =10000   
616-207-00-X polyhexamethylene  biguanide hydrochloride 
  27083-27-8 or 
32289-58-0 Carc. 2 
Acute Tox. 4 STOT RE 1 Eye Dam. 1 
Skin Sens. 1B 
Aquatic Acute 1 Aquatic 
Chronic 1 H351 
H302 H372 (respiratory 
tract) 
(inhalation) H318 
H317 
H400 H410 GHS05 
GHS08 GHS09 Dgr H351 
H302 H372 (respiratory 
tract) 
(inhalation)  H318 
H317 
 H410  M =10 
M =10   
616-208-00-5 N-ethyl-2-pyrrolidone; 
1-ethylpyrrolidin-2-one  
 220-250-6 2687-91-4 Repr. 1B H360D GHS08 
Dgr 
 H360D 
    
616-209-00-1 amidosulfuron (ISO); 
3-(4,6-dimethoxypyrimidin-2-yl)-1-((N-
methyl-N-methylsulfonylamino)sulfonyl)urea 
 407-380-0 120923-37-7  Aquatic Acute 1  
Aquatic 
Chronic 1 H400 
H410 GHS09 
Wng H410  M =100 
M =100 
  
616-210-00-6 tebufenpyrad (ISO); 
N-(4-tertbutylbenzyl)- 
4-chloro-3-ethyl-1-methyl-1Hpyrazole-5- carboxamide  119168-77-3 Acute Tox. 3 
Acute Tox. 4 
STOT RE 2 Skin Sens. 1B 
Aquatic Acute 1 
Aquatic Chronic 1 H301 
H332 
H372 (Gastrointesti
nal tract) 
(Oral) H317 
H400 
H410 GHS06 
GHS09 
Dgr H301 
H332 
H372 (Gastrointesti
nal tract) 
(Oral) H317 
 
H410  M =10  
M =10 
  
616-211-00-1 proquinazid (ISO);  
6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one   189278-12-4 Carc. 2 
Aquatic Acute 1 Aquatic Chronic 1 H351 
H400 H410 GHS08 
GHS09 Wng H351 
 H410  M =1  
M =10     
EN 13   EN  
ANNEX III  
 
Index No  
International Chemical Identification  
EC No  
CAS No  
Classification  
Labelling  
Concentration Limits  
Notes 
015-004-00-8 aluminium phosphide 244-088-0 20859-73-8 F; R15/29 
T+; R26/28 Xn; R21 
R32 
N; R50 F; T+; N 
R: 15/29-21- 26/28-32-50 
S: (1/2-)3/9/14/49- 
8-22-30-36/37-43- 45-60-61 N; R50: C ≥ 0.25 %  
015-005-00-3 magnesium phosphide; 
trimagnesium diphosphide 235-023-7 12057-74-8 F; R15/29 
T+; R26/28 Xn; R21 R32 
N; R50 F; T+; N 
R: 15/29-21- 26/28-32-50 S: (1/2-)3/9/14/49- 
8-22-30-36/37-43- 
45-60-61 N; R50: C ≥ 0.25%  
015-123-00-5 fenamiphos (ISO); 
ethyl-4-methylthio -m-tolyl isopropyl 
phosphoramidate 244-848-1 22224-92-6 T+; R26/28 
T; R24 Xi; R36 
N; R50-53 T+; N 
R: 24-26/28-36-  50/53 
S: (1/2-)23-26-28- 
35-36/37-45-60- 61 N; R50-53: C ≥ 0.25 % 
N; R51-53: 0.025 % ≤ C < 0.25 
% 
R52-53: 0.0025 % ≤ C < 0.025 
%  
030-012-00-1 aluminium-magnesium-zinc-carbonate-
hydroxide 
 423-570-6 169314-88-9 R53 R: 53 
S: 61   
602-006-00-4 chloroform; 
trichloromethane 200-663-8 67-66-3 Carc. Cat. 3; R40 
Repr. Cat. 3; R63 
Xn; R20/22-48/20 Xi; R36/38 
 Xn 
R: 20/22-36/38- 
40-48/20-63 S: (2-)36/37   
603-097-00-3 1,1',1''-nitrilotripropan-2-ol; 
triisopropanolamine 204-528-4 122-20-3 Xi; R36 Xi 
R: 36 
S: (2-)26   
605-008-00-3 acrolein; 
prop-2-enal; acrylaldehyde 203-453-4 107-02-8 F; R11 
T+; R26/28 T; R24 
C; R34 F; T+; C; N 
R: 11-24-26/28- 34-50 
S: (1/2-)23-26- C; R34: C ≥ 0.1% 
N; R50: C ≥ 0.25% D  
EN 14   EN N; R50 28-36/37/39-45- 
61 
607-023-00-0 vinyl acetate 203- 545-4 108-05-4 F; R11  
Carc. Cat. 3; R40 Xn; R20 
Xi; R37 F; Xn 
R: 11-20-37-40 S: 9-16-33-36/37  D 
607-613-00-8 reaction mass of;  
succinic acid 
monopersuccinic acid  dipersuccinic acid 
monomethyl ester of succinic acid 
monomethyl ester of persuccinic acid dimethyl succinate 
glutaric acid 
monoperglutaric acid  diperglutaric acid monomethyl ester of glutaric acid 
monomethyl ester of perglutaric acid 
dimethyl glutarate  adipic acid 
monoperadipic acid  
diperadipic acid monomethyl ester of adipic acid 
monomethyl ester of peradipic acid 
dimethyl adipate hydrogen peroxide 
methanol 
water  
 432-790-1  C; R34 
Xn; R20/21/22- 
68/20/21/22  C 
R: 20/21/22-34- 
68/20/21/22 S: (1/2-)26-28- 
36/37/39-45   
609-003-00-7 Nitrobenzene 202-716-0 98-95-3 Carc. Cat. 3; R40 
Repr. Cat. 2; R60 
T; R23/24/25-  48/23/24/25 
R52-53 T 
R: 23/24/25- 
48/23/24/25-40- 60-52/53 
S: (1/2-)27-36/37- 
45-46-53   
612-120-00-6 aclonifen (ISO); 
2-chloro-6-nitro- 3-phenoxyaniline 
 277-704-1 74070-46-5 Carc. Cat. 3; R40 
R43 N; R50-53 Xn; N 
R: 40-43-50/53 S: (2-)36/37-60- 
61 R43: C ≥ 0.1%  
N; R50-53: C ≥ 0.25 %  
N; R51-53: 0.025 % ≤ C < 0.25 
% 
R52-53: 0.0025 % ≤ C < 0.025 
%   
EN 15   EN 613-175-00-9 epoxiconazole (ISO); 
(2RS,3SR)-3-(2-chlorophenyl)-2-(4-fluorophenyl)-[(1H-1,2,4-triazol-1-
yl)methyl]oxirane 
 406-850-2 133855-98-8 Carc. Cat. 3; R40 
Repr. Cat. 2; R61 Repr. Cat. 3; R62 
N; R51-53 T; N 
R: 61-40-62-51/53 S: 45-53-61   
616-200-00-1 reaction mass  of N,N'-ethane-1,2-
diylbis(hexanamide) and 12-hydroxy-N-[2-[(1-oxyhexyl)amino]et hyl]octadecanamide 
and N,N'-ethane-1,2-diylbis(12-
hydroxyoctadecan amide)  432-430-3  R53 R: 53 
S: 61   
648-055-00-5 pitch, coal tar, high-temp.;  
pitch; [The residue from the distillation of high 
temperature coal tar. A black solid with an 
approximate softening point from 30 °C to 180 °C (86 °F to 356 °F). Composed 
primarily of a complex mixture of three or 
more membered condensed ring aromatic hydrocarbons.] 
 266-028-2 65996-93-2 Carc. Cat. 1; R45 
Muta. Cat. 2; R46 Repr. Cat. 2; R60-61 
N; R50-53 T; N 
R: 45-46-60-61- 50/53 
S: 45-53-60-61 N; R50-53: C ≥ 0.025 % 
N; R51-53: 0.0025 % ≤ C <  
0.025 % 
R52-53: 0.00025 % ≤ C <  
0.0025 %   
649-330-00-2 naphtha (petroleum), 
hydrodesulphurized heavy;  
Low boiling point hydrogen treated naphtha;[A complex combination of hydrocarbons 
obtained from a catalytic 
hydrodesulfurization process. It consists of hydrocarbons having carbon numbers 
predominantly in the range of C7 through 
C12 and boiling in the range of approximately 90 °C to 230 °C (194 °F to 
446 °F).] 
 265-185-4 64742-82-1 Carc. Cat. 2; R45 
Muta. Cat. 2; R46 
Xn; R48/20-65 T 
R: 45-46-48/20-65 
S: 53-45  P 
649-345-00-4 stoddard solvent; 
Low boiling point naphtha — unspecified; 
[A colourless, refine d petroleum distillate 
that is free from rancid or objectionable odours and that boils in a range of approximately 148,8 °C to 204,4 °C (300  
°F to 400 °F).] 
 232-489-3 8052-41-3 Carc. Cat. 2; R45 
Muta. Cat. 2; R46 Xn; R48/20-65 T 
R: 45-46-48/20-65 S: 53-45  P 
649-405-00-X solvent naphtha (petroleum), medium  aliph.; 265-191-7 64742-88-7 Xn; R48/20-65 Xn    
EN 16   EN Straight run kerosine; 
[A complex combination of hydrocarbons obtained from the distilla tion of crude oil or 
natural gasoline. It consists predominantly 
of saturated hydrocarbons having carbon numbers predominantly in the range of C9 
through C12 and boiling in the range of 
approximately 140 °C to 220 °C (284 °F to 428 °F).] 
 R: 48/20-65 
S: (2-)23-24-62  
EN 17   EN  
ANNEX IV  
 
Index No  
International Chemical Identification  
EC No  
CAS No  
Classification  
Labelling  
Concentration Limits  
Notes 
031-001-00-4 gallium arseni de 215-114-8 1303-00-0 Carc. Cat. 2; R45 
T; R48/23  T  
R: 45-48/23  S: 53-45  E 
050-025-00-6 trichloromethylstannane  213-608-8 993-16-8 Repr. Cat. 3; R63 Xn 
R: 63 S: (2-)22-36/37   
050-026-00-1 2-ethylhexyl 10-ethyl-4-[[2-[(2-
ethylhexyl)oxy]-2-oxoethyl]thio]-4-methyl-7-oxo-8-oxa-3,5-dithia-4-
stannatetradecanoate  
 260-828-5 57583-34-3 Repr. Cat. 3; R63 Xn 
R: 63 S: (2-)22-36/37   
050-027-00-7 2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-
oxa-3,5-dithia-4-stannatetradecanoate 239-622-4 15571-58-1 Repr. Cat. 2; R61 T 
R: 61 S: 45-53   
601-087-00-3 2,4,4-trimethylpentene 246-690-9 25167-70-8 F; R11 
Xn; R65 
R67 F; Xn 
R: 11-65-67 
S: 9-16-33-62  D 
606-145-00-1 sulcotrione (ISO); 
2-[2-chloro-4-
(methylsulfonyl)benzoyl]cyclohexane-1,3-dione 
  99105-77-8  Repr. Cat. 3; R63 
Xn; R48/22 
R43 N; R50-53 Xn; N 
R: 43-48/22-63- 50/53 S: (2-)22-36/37- 60-61 N; R50-53: C ≥ 25 % 
N; R51-53: 2.5 % ≤ C < 25 % 
R52-53: 0.25 % ≤ C< 2.5 % 
R43: C ≥ 0.1% 
  
607-699-00-7 bifenthrin (ISO); 
(2-methylbiphenyl-3-yl)methyl rel-(1R,3R)-
3-[(1 Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-
yl]-2,2-dimethylcy clopropanecarboxylate 
  82657-04-3 Carc. Cat 3; R40 
T; R23/25 Xn; R48/22 
R43 
N; R50-53 T; N 
R: 23/25-40-43- 48/22-50/53 
S: (1/2-)23-24- 
36/37-38- 45-60-61 N; R50-53: C ≥ 0.0025 % 
N; R51-53: 0.00025 % ≤ C<  
0.0025 % 
R52-53: 0.000025 % ≤ C <  
0.00025 %    
EN 18   EN 607-700-00-0 i ndoxacarb (ISO); 
methyl (4a S)-7-chloro-2-
{(methoxycarbonyl)[4-
(trifluoromethoxy)phenyl]carbamoyl}-2,5-
dihydroindeno[1,2- e][1,3,4]oxadiazine-
4a(3H)-carboxylate  173584-44-6 T; R25-48/25 
Xn; R20 R43 
N; R50-53 T; N 
R: 20-25-43- 48/25-50/53 
S: (1/2-)24-37-45- 
60-61 N; R50-53: C ≥ 25 % 
N; R51-53: 2.5 % ≤ C < 25 % 
R52-53: 0.25 % ≤ C < 2.5 %  
607-701-00-6 reaction mass of  (S)- Indoxacarb and (R)- 
Indoxacarb 75:25; 
methyl 7-chloro-2-{(methoxycarbonyl)[4-
(trifluoromethoxy)phenyl]carbamoyl}-2,5-dihydroindeno[1,2- e][1,3,4]oxadiazine-
4a(3H)-carboxylate  144171-61-9 T; R48/25 
Xn; R20/22 
R43 
N; R50-53 T; N 
R: 20/22-43- 
48/25-50/53 
S: (1/2-)24-37-45- 60-61 N; R50-53: C ≥ 25 % 
N; R51-53: 2.5 % ≤ C < 25 % 
R52-53: 0.25 % ≤ C < 2.5 %  
607-702-00-1 dihexyl phthalate 
 201-559-5 84-75-3 Repr. Cat. 2; R60-61 T 
R: 60-61 
S: 53-45 
   
607-703-00-7 ammoniumpentade 
cafluorooctanoate 223-320-4 3825-26-1 Carc. Cat. 3; R40 
Repr. Cat. 2; R61 R64 
T; R48/23 
Xn; R20/22- 48/21/22  
Xi; R41 T; Xn 
R: 61-20/22-40- 41- 48/23- 
48/21/22-64 
S: 53-45   
607-704-00-2 perfluorooctanoic 
acid 206-397-9 335-67-1 Carc. Cat. 3; R40 
Repr. Cat. 2; R61 
R64 T; R48/23 
Xn; R20/22- 
48/21/22 Xi; R41 
 T; Xn 
R: 61-20/22-40- 
41-48/23- 48/21/22-64 
S: 53-45   
612-282-00-8 octadecylamine 204-695-3 124-30-1 Xn; R48/22-65 
Xi; R38-41 
N; R50-53  Xn; N 
R: 38-41-48/22- 
65-50/53 S: (2-)26- 
36/37/39-60-61- 
62 N; R50-53: C ≥ 2.5 % 
N; R51-53: 0.25 % ≤ C < 2.5 % 
R52-53: 0.025 % ≤ C < 0.25 %  
612-283-00-3 (Z)-octadec-9-enylamine 204-015-5 112-90-3 Xn; R22-48/22-65 
C; R34 N; R50-53 C; N  
R: 22-34-48/22- 65-50/53 S: (1/2-)23-26- 
36/37/39-45-60- 
61-62 C; R34: C ≥ 10% 
Xi; R36/37/38: 5 % ≤ C < 10% 
N; R50-53: C ≥ 2.5 % 
N; R51-53: 0.25 % ≤ C < 2.5 % 
R52-53: 0.025 % ≤ C < 0.25 %   
EN 19   EN 612-284-00-9 amines, hydrogenated tallow alkyl 
 262-976-6 61788-45-2 Xn; R48/22-65 
Xi; R38-41 N; R50-53 Xn; N 
R: 38-41-48/22- 65-50/53 
S: (2-)26- 
36/37/39-60-61- 62 N; R50-53: C ≥ 2.5 % 
N; R51-53: 0.25 % ≤ C < 2.5 % 
R52-53: 0.025 % ≤ C < 0.25 % 
  
612-285-00-4 amines, coco alkyl 262-977-1 61788-46-3 Xn; R22-48/22-65 
C; R35 
N; R50-53 C; N  
R: 22-35-48/22- 
65-50/53 
S: (1/2-)23-26- 36/37/39-45-60- 
61-62 C; R35: C ≥ 10% 
C; R34: 5 % ≤ C < 10% 
Xi; R36/37/38: 1% ≤ C < 5 % 
N; R50-53: C ≥ 2.5 %  
N; R51-53: 0.25 % ≤ C < 2.5 % 
R52-53: 0.025 % ≤ C < 0.25 %  
612-286-00-X amines, tallow alkyl 263-125-1 61790-33-8 Xn; R22-48/22-65 
C; R35 
N; 50-53 C; N  
R: 22-35-48/22- 
65-50/53 
S: (1/2-)26- 36/37/39-45-60- 
61-62 N; R50-53: C ≥ 2.5 % 
N; R51-53: 0.25 % ≤ C < 2.5 % 
R52-53: 0.025 % ≤ C < 0.25 % 
  
616-206-00-4 flufenoxuron (ISO); 
1-(4-(2-cloro- α,α,α-p-trifluorotolyloxy)-2-
fluorophenyl)-3-(2,6-difluorobenzolyl)urea  417-680-3 101463-69-8 R64 
R33 
N; R50-53 N 
R: 33-64-50/53 
S: (2-)22-36/37-46-  60-61 N; R50-53 C > 0.0025 % 
N; R51-53 0.00025 % < C <  
0.0025 % R52-53 0.000025 % < C <  
0.00025 % 
  
616-207-00-X polyhexamethylene biguani de hydrochloride  27083-27-8 or 
32289-58-0 Carc. Cat 3; R40 
Xn; R22 T; R48/23 
Xi; R41-43 
N; R50-53 T; N 
R: 22-40-41- 43-48/23-50/53 
S: (1/2-)22- 
36/37/39-45-60- 61 N; R50-53: C ≥ 2.5 % 
N; R51-53: 0.25 % ≤ C ≤ 2.5 
R52-53: 0.025 % ≤ C ≤ 0.25 % 
  
616-208-00-5 N-ethyl-2-pyrrolidone; 
1-ethylpyrrolidin-2-one 220-250-6 2687-91-4 Repr. Cat. 2; R61 
 T 
R: 61 
S: 53-45 
   
616-209-00-1 amidosulfuron (ISO); 
3-(4,6-dimethoxypyrimidin-2-yl)-1-((N-methyl-N-
methylsulfonylamino)sulfonyl)urea 
 407-380-0 120923-37-7 N; R50-53 N 
R: 50/53 N; R50-53: C ≥0.25% 
N; R51-53: 0.025% ≤ C <0.25% 
R52-53: 0.0025% ≤ C <0.025% 
  
616-210-00-6 tebufenpyrad (ISO); 
N-(4-tertbutylbenzyl)- 
4-chloro-3-ethyl-1-methyl-1Hpyrazole-5-  119168-77-3 
 Xn; R20/22 
R43 Xn; N 
R: 20/22-43- N; R50-53: C ≥ 2.5 % 
N; R51-53: 0.25 % ≤ C < 2.5 %   
EN 20   EN  carboxamide N; R50-53 50/53 
S: (2-)24-37-46- 
60-61 R52-53: 0.025 % ≤ C < 0.25 % 
616-211-00-1 proquinazid (ISO);  
6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one 
  189278-12-4 Carc. Cat. 3; R40 
N; R50-53 Xn; N 
R: 40-50/53 S: (2-)36/37-46- 
60-61