(Attachment)  
 
Designation of Shitei Yakubutsu  (designated substances) based on the Act on 
Securing Quality, Efficacy and Safety of Products Including Pharmaceuticals and 
Medical Devices  (1960, Law No.145)  
 
In order to prevent the abuse of substances with probable effects on the central nervous 
system and to clarify the regulation under the Act on Securing Quality, Efficacy and 
Safety of Products Including Pharmaceuticals and Medical Devices  (hereinafter referred 
to as the Act ), the Minister of Health, Labour and Welfare of Japan proposes to 
additionally designa te the following substances as Shitei Yakubu tsu (designated 
substances). Manufacture, import, sale, s imple ownership and the use of designated 
substances  are bann ed except for the proper uses  (see below).  
 
● The proposed substances as Shitei Yakubutsu   
*Abbreviation is put in parentheses.  
 
1 substance  
1. N,N-Diethyl -7-methyl -4-(thiophene -2-carbonyl) -4,6,6a,7,8,9 -hexahydroindolo
[4,3-fg]quinoline -9-carboxamide  
［1T-LSD］ 
 
3 substance  groups  
1. Any compounds in which a hydroxy or an acetoxy group is bonded to the 1 -
position, and a linear alkyl group (the number of carbon atoms is limited from 3 
to 8) is bonded to the 3 -position and no further substituents are attached other than 
at the 1 - and 3 -positions of 6a,7,8,10a -tetrahydro -6,6,9 -trimethyl -6H-
dibenzo[ b,d]pyran, and salts of the se compounds. Except in the case of narcotics 
as defined in the Narcotics and Psychotropics Control Law.  
 
O R2R1
 
 
Additional designated substances: Δ9-THCV -O-acetate  (R1=-OC(=O)CH 3, R2=n-C3H7), 
Δ9-THCB -O-acetate  (R1=-OC(=O)CH 3, R2=n-C4H9), Δ9-THCH -O-acetate  (R1=-
OC(=O)CH 3, R2=n-C6H13), Δ9-THCP -O-acetate  (R1=-OC(=O)CH 3, R2=n-C7H15), Δ9-
THCjd -O-acetate  (R1=-OC(=O)CH 3, R2=n-C8H17). 
  
2. Any compounds in which a hydroxy or an acetoxy group is bonded to the 1-
position, and a linear alkyl group (the number of carbon atoms is limited from 3 
to 8) is bonded to the 3 -position and no further substituents are attached other than 
at the 1 - and 3 -positions of 6a,7,10,10a -tetrahydro -6,6,9 -trimethyl -6H-
dibenzo[ b,d]pyran, and salts of these compounds. Except in the case of narcotics 
as defined in the Narcotics and Psychotropics Control Law.  
 
O R2R1
 
 
Additional designated substances: Δ8-THCV -O-acetate  (R1=-OC(=O)CH 3, R2=n-C3H7), 
Δ8-THCB -O-acetate  (R1=-OC(=O)CH 3, R2=n-C4H9), Δ8-THCH -O-acetate  (R1=-
OC(=O)CH 3, R2=n-C6H13), Δ8-THCP -O-acetate  (R1=-OC(=O)CH 3, R2=n-C7H15), Δ8-
THCjd -O-acetate  (R1=-OC(=O)CH 3, R2=n-C8H17). 
 
3. Any compounds in which a hydroxy or an acetoxy group is bonded to the 1 -
position, and a linear alkyl group (the number of carbon atoms is limited from 3 
to 8) is bonded to the 3 -position and no further substituents are attached other than 
at the 1 - and 3 -positions of 6a,7,8,9,10,10a -hexahydro -6,6,9 -trimethyl -6H-
dibenzo[ b,d]pyran, and salts of these compounds.  
 
O R2R1
 
 
Additional designated substances: HHCV -O-acetate  (R1=-OC(=O)CH 3, R2=n-C3H7), 
HHCB -O-acetate  (R1=-OC(=O)CH 3, R2=n-C4H9), HHCH -O-acetate  (R1=-OC(=O)CH 3, 
R2=n-C6H13), HHCP -O-acetate  (R1=-OC(=O)CH 3, R2=n-C7H15), HHCjd -O-acetate  (R1=-
OC(=O)CH 3, R2=n-C8H17). 
 
 
● The propos ed proper uses for the above Shitei Yakubutsu  are; 
1.  To be used for researches or tests at the government, the local governments, 
agencies thereof, technical colleges, inter -university research institutes,  the 
independent administrative agencies and the local independent administrative 
agencies  
2.  To be used for tests under the Act, and  
3.  To be used for forensic use