COMMISSION REGUL ATION (EU) No 497/2014 
of 14 May 2014 
amending Annex II to Regulation (EC) No 1333/2008 of the European Parliament and of the 
Council and the Annex to Commission Regulation (EU) No 231/2012 as regards the use of Advan ­
tame as a sweetener 
(Text with EEA relevance) 
THE EUR OPEAN COMMISSION, 
Having regar d to the Treaty on the Functioning of the European Union, 
Having regard to Regulation (EC) No 1333/2008 of the European Parliament and of the Council of 16 December 2008 
on food additives (1), and in particular Articles 10(3) and 14 thereof, 
Having regard to Regulation (EC) No 1331/2008 of the European Parliament and of the Council of 16 December 2008 
establishing a common author isation procedure for food additives, food enzymes and food flavouri ngs (2), and in par­
ticular Article 7(5) thereof, 
Whereas: 
(1)  Annex II to Regulation (EC) No 1333/2008 lays down a Union list of food additives appro ved for use in foods 
and their conditions of use. 
(2)  Commission Regulation (EU) No 231/2012 (3) lays down specifications for food additives listed in Annex es II 
and III to Regulation (EC) No 1333/2008. 
(3)  Those lists may be updat ed in accordance with the common procedure refer red to in Article 3(1) of Regulation 
(EC) No 1331/2008, either on the initiative of the Commission or following an application. 
(4)  An application for author isation of the use of Advantame as a sweet ener in several food catego ries was submitte d 
in May 2010. The application was made available to the Member State s pursuant to Article 4 of Regulation (EC) 
No 1331/2008. 
(5)  There is a technological need for the use of Advantame as a high-inte nsity sweetener in various food and tabletop 
products in order to replace calor ic sugars (sucrose, glucose, fructo se, etc.) thus allowing for a reduction of the 
calor ic cont ent of those foodstuffs. The addition of Advantame as a sweet ener to the catego ries of foods in which 
high-int ensity sweet eners are author ised according to Annex II to Regulation (EC) No 1333/2008 will provide 
manuf acturers with greater flexibility in formulating energy-reduced foods with a similar taste prof ile as the full- 
calor ic equivalent. The flavour and sweetness qualities of Advantame, coupled with good stability character istics, 
mean that Advantame provides an altern ative to already appro ved high-int ensity sweet eners, offering consumers 
and the food industr y the option to choose from a wider selection of sweetene rs, thus reducing the intake of each 
individual sweetene r. 
(6)  The European Food Safety Author ity (‘the Auth ority’) evaluated the safet y of Advantame when used as a food 
additive and expressed its opinion on 31 July 2013 (4). The Author ity established an Acceptable Daily Intake 
(ADI) for Advantame of 5 mg/kg bw/da y. Conser vative estimates of advantame exposure for high level adults and 
children consumers were belo w the ADI for the proposed use levels. After consider ing all the data on stability , 
degradation products, toxicology and exposure, the Author ity concluded that Advantame would not be of safety 
concer n at the proposed uses and use levels as a sweetene r. 15.5.2014 L 143/6 Official Jour nal of the European Union EN     
(1)OJ L 354, 31.12.2008, p. 16. 
(2)OJ L 354, 31.12.2008, p. 1. 
(3)Commission Regulation (EU) No 231/2012 of 9 March 2012 laying down specificatio ns for food additives listed in Annexes II and III to 
Regulation (EC) No 1333/2008 of the European Parliament and of the Council (OJ L 83, 22.3.2012, p. 1). 
(4)EFSA Jour nal 2013; 11(7):3301. (7)  Theref ore, it is appropr iate to author ise the use of Advantame as a sweetener in the food categor ies specifi ed in 
Annex I to this Regulation and to assign E 969 as an E-number to that food additive. 
(8)  The specif ications for Advantame should be included in Regulation (EU) No 231/2012 when it is included in the 
Union list of food additives laid down in Annex II to Regulation (EC) No 1333/2008 for the first time. 
(9)  Regulations (EC) No 1333/2008 and (EU) No 231/2012 should theref ore be amended according ly. 
(10)  The measures provided for in this Regulation are in accordance with the opinion of the Standing Committ ee on 
the Food Chain and Animal Health, 
HAS ADOPTED THIS REGUL ATION: 
Article 1 
Annex II to Regulation (EC) No 1333/2008 is amended in accordance with Annex I to this Regulation. 
Article 2 
The Annex to Regulation (EU) No 231/2012 is amended in accordance with Annex II to this Regulation. 
Article 3 
This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the 
European Union. 
This Regulation shall be binding in its entirety and directly applicable in all Member State s. 
Done at Brussels, 14 May 2014. 
For the Commission 
The Presid ent 
José Manuel BARR OSO  15.5.2014 L 143/7 Official Jour nal of the European Union EN     ANNEX I 
Annex II to Regulation (EC) No 1333/2008 is amended as follows: 
(1)  In Part B, in Table 2 ‘Sweeteners’, the following new entr y is inser ted after the entr y for food additive E 968 Erythr itol: 
‘E 969 Advantame ’  
(2)  In Part E, the following entr ies for E 969 are inser ted in numer ical order in the food catego ries refer red to: 
PART E: AUTHORISED FOOD ADDITIVES AND CONDITIONS OF USE IN FOOD CATEGORIES 
Categ ory 
number E -Number Name Maximum level 
(mg/l or mg/kg 
as appropr iate) Footnotes restr ictions/excep tion 
01.4 Flav oured fermented milk products including heat-treated products  
‘E 969 Advantame 10  only energy-reduced products or with no added sugar’ 
03 Edible ices  
‘E 969 Advantame 10  only energy-reduced or with no added suga r’ 
04.2.2 Fruit and veget ables in vinegar , oil, or brine  
‘E 969 Advantame 3  only sweet-sour preser ves of fruit and vege tables’ 
04.2.3 Canned or bottled fruit and vegetables  
‘E 969 Advantame 10  only fruit energy-reduced or with no added sugar’ 
04.2.4.1 Fruit and veget able preparations excluding compote  
‘E 969 Advantame 10  only energy-reduced’ 
04.2.5.1 Extra jam and extra jelly as defined by Directiv e 2001/113/EC  
‘E 969 Advantame 10  only energy-reduced jams jellies and mar malades ’ 
04.2.5.2 Jam, jellies and mar malades and sweetened chest nut puree as defined by Directiv e 2001/113/EC  
'E 969 Advantame 10  only energy-reduced jams, jellies and mar malades' 15.5.2014 L 143/8 Official Jour nal of the European Union EN     Categ ory 
number E -Number Name Maximum level 
(mg/l or mg/kg 
as appropr iate) Footnotes restr ictions/excep tion 
04.2.5.3 Other similar fruit or vegetabl e spreads  
‘E 969 Advantame 10  only dried-fr uit-based sandwich spreads, energy-reduced or with no added sugar ’ 
05.1 Cocoa and Chocolate products as covered by Directiv e 2000/36/EC  
‘E 969 Advantame 20  only energy-reduced or with no added suga rs’ 
05.2 Other confecti oner y including breath refreshening microsw eets  
‘E 969 Advantame 20  only cocoa or dried fruit based, energy reduced or with no added sugar  
E 969 Advantame 10  only cocoa, milk, dried fruit or fat based sandwich spreads, energy-reduced or with no added sugar  
E 969 Advantame 20  only starc h based confe ctionar y energy reduced or with no added sugar  
E 969 Advantame 10  only confectionary with no added sugar  
E 969 Advantame 60  only breath-freshening micro-sweets, with no added sugar  
E 969 Advantame 20  only strong ly flavoured freshening throat pastilles with no added sugar’ 
05.3 Chewing gum  
‘E 969 Advantame 200  only with added suga rs or poly ols, as flavour enhancer  
E 969 Advantame 400  only with no added sugar ’ 
05.4 Decorations, coatings and fillings, except fruit based fillings covered by categor y 4.2.4  
‘E 969 Advantame 20  only starc h based confe ctionar y energy reduced or with no added sugar  
E 969 Advantame 10  only confectionary with no added sugar  
E 969 Advantame 20  only cocoa or dried fruit based, energy reduced or with no added sugar  
E 969 Advantame 4  only sauces’ 15.5.2014 L 143/9 Official Jour nal of the European Union EN     Categ ory 
number E -Number Name Maximum level 
(mg/l or mg/kg 
as appropr iate) Footnotes restr ictions/excep tion 
06.3 Breakfast cereals  
‘E 969 Advantame 10  only breakfast cereals with a fibre cont ent of more than 15 %, and containing at least 20 % bran, 
energy reduced or with no added sugar’ 
07.2 Fine bakery wares  
‘E 969 Advantame 10  only essoblate n — wafer paper  
E 969 Advantame 17  only fine baker y products for special nutr itional uses’ 
09.2. Processed fish and fisher y products including mollusks and crustaceans  
‘E 969 Advantame 3  only sweet-sour preser ves and semi preser ves of fish and mar inades of fish, crustaceans and molluscs ’ 
11.4.1 Table Top Sweeteners in liquid form  
‘E 969 Advantame quantum satis ’   
11.4.2 Table Top Sweeteners in powder form  
‘E 969 Advantame quantum satis'’   
11.4.3 Table Top Sweeteners in tablets  
‘E 969 Advantame quantum satis ’   
12.4 Must ard  
‘E 969 Advantame 4’   
12.5 Soups and broths  
‘E 969 Advantame 2  only energy-reduced soups’ 
12.6 Sauces  
‘E 969 Advantame 4’   15.5.2014 L 143/10 Official Jour nal of the European Union EN     Categ ory 
number E -Number Name Maximum level 
(mg/l or mg/kg 
as appropr iate) Footnotes restr ictions/excep tion 
12.7 Salads and savour y based sandwich spreads  
‘E 969 Advantame 4  only Feinkostsalat’ 
13.2 Diet ary foods for special medical pur poses defined in Directiv e 1999/21/EC (excl uding products from food categor y 13.1.5)  
‘E 960 Advantame 10’   
13.3 Diet ary foods for weight control diets intended to replace total daily food intake or an individual meal (the whole or part of the total daily diet)  
‘E 960 Advantame 8’   
14.1.3 Fruit nectars as defined by Council Directiv e 2001/112/EC and veget able nectars and similar products  
‘E 969 Advantame 6  only energy-reduced or with no added suga r’ 
14.1.4 Flav oured drinks  
‘E 969 Advantame 6  only energy reduced or with no added sugar’ 
14.2.1 Beer and malt bev erages  
‘E 969 Advantame 6  only alcohol-free beer or with an alcohol cont ent not exceed ing 1,2 % vol; “Bière de table/T afelbier/ 
Table beer” (original wort content less than 6 %) excep t for “Obergäriges Einf achbi er”; Beers with a 
minimum acidity of 30 milli-equivalents expressed as NaOH; Brown beers of the “oud bruin” type  
E 969 Advantame 0,5  only energy-reduced beer ’ 
14.2.3 Cider and perry  
‘E 969 Advantame 6’   
14.2.8 Other alcholic drinks including spir its with less than 15 % of alcohol and mixtures of alcoholic drinks with non-alcoholic drinks  
‘E 969 Advantame 6’   
15.1 Potato-, cereal-, flour - or starch-based snacks  
‘E 969 Advantame 5’   15.5.2014 L 143/11 Official Jour nal of the European Union EN     Categ ory 
number E -Number Name Maximum level 
(mg/l or mg/kg 
as appropr iate) Footnotes restr ictions/excep tion 
15.2 Processed nuts  
‘E 969 Advantame 5’   
16. Desser ts excluding products covered in categor y 1, 3 and 4  
‘E 969 Advantame 10  only energy-reduced or with no added suga r’ 
17.1 Food supplements supplied in a solid form including capsules and table ts and similar forms  
‘E 969 Advantame 20’   
17.2 Food supplements supplied in a liquid form  
‘E 969 Advantame 6’   
17.3 Food supplements supplied in a syrup-type or chewable form  
‘E 969 Advantame 55’      15.5.2014 L 143/12 Official Jour nal of the European Union EN     ANNEX II 
In the Annex to Regulation (EU) No 231/2012, the following new entr y is inser ted after the entr y for food additive 
E 968: 
‘E 969 ADVANT AME 
Synon yms  
Def inition Advantame (ANS9801) is produced by chemical synthesis in a three-st ep 
process; production of the principal manufactur ing intermediat e, 3-hydro xy-4- 
metho xycinnamaldehyde (HMC A), followed by hydrogenation to form 3-(3- 
hydro xy-4-metho xyphen yl) propionaldehyde (HMP A). In the final step , the 
HMP A methanol solution (filtrate ) is combined with aspar tame to give the 
imine that under selective hydrogenation forms advantame. The solution is 
allowed to crystallise and crude crystals are washed. The product is re-cr ystal ­
lised and crystals are separated, washed and dried. 
CAS No. 714229-20-6 
Chemical name N-[N-[3-(3-hydro xy-4-metho xyphenyl) prop yl]-α-aspar tyl]-L-phe nylalanine 1- 
methyl ester, monohydrat e (IUP AC); 
L-pheny lalanine, N-[3-(3-hydro xy-4-metho xyphenyl) prop yl]-L- alpha-aspar tyl-, 
2-methyl ester , monoh ydrate (CA) 
Molecular formula C24H30N2O7·H2O 
Molecular weight 476,52 g/mol (monohydr ate) 
Assa y Not less than 97,0 % and not more than 102,0 % on an anhydrous basis 
Descr iption White to yellow powder 
Identif ication  
Melting Point 101,5 °C 
Purity  
N-[N-[3-(3-h ydro xy-4-metho xy­
pheny l)prop yl-α-aspar tyl]-L-phe ny­
lalanine (ANS9801-acid) Not more than 1,0 % 
Total other relat ed substances Not more than 1,5 % 
Residual Solvents Isoprop yl acetat e: Not more than 2 000 mg/kg 
Methyl acetate : Not more than 500 mg/kg 
Methanol: Not more than 500 mg/kg 
2-Propanol: Not more than 500 mg/kg 
Water content Not more than 5,0 % (Karl Fischer method) 
Residue on ignition Not more than 0,2 % 
Arsenic Not more than 2 mg/kg 
Lead Not more than 1 mg/kg 
Palladium Not more than 5,3 mg/kg 
Platinum Not more than 1,7 mg/kg’   15.5.2014 L 143/13 Official Jour nal of the European Union EN