◼ Revision of  Specifications and Standards  to Updat e the Official 
Compilation of Food Additives  
 
The government of Japan wi ll revise t he ex isting specifications and standards for food 
additives . 
 
Summary  
Japan prohibits the sale of food additives that are not designated by the Minister of 
Health, Labour and Welfare (“the Minister”) under Article 12 of the Food Sanitation Act 
(“the Act”). In addition, when specifications or standards for food additives are stipulated 
pursuant to Article 13 of the Act,  the sale of those additives are prohibited  unless they 
meet the specifications or the standards.  
 
The specifications a nd standards established based on Article 13, paragraph (1)  of the 
Act are  stipulated in the Specifications and Standards for Foods, Food Additives, Etc. 
(Public Notice of the Ministry of Health and Welfare No. 370 of 1959 , “the Public Notice ”). 
The Public Notice  contains general notices, general tests, and reagents and solution s 
required for the t esting of food additives as well as compositional specifications for 
additives and standards for the storage, manufacturing, and use there of. 
 
On the  other hand, t he Act requires the Minist er and the Prime Minister , in Article 21  
of the Act , to prepare the Official Compilation  of Food Additives  contain ing compositional 
specifications and standards for food additives  based on Article 13,  paragraph (1) . In 
1960 the first edition of the compilation was prepared . Since then , the compilation ha d 
been updated regularly  until t he publication  of the ninth  edition  in 2018 . 
 
In March 2023 , in response to a request from the Minister, the Committee on Food 
Additives of the Food Sanitation Council that is established under the Pharmaceutical 
Affairs and Food Sanitation Council discussed whether it is adequate to revise the 
specifications and standards  for food additives to update  the official c ompilation of food 
additives . 
 
The committee  concluded that the Minister should revise the specifications and 
standards based on Article 13 of the Act. 
 
Process to prepare the tenth edition of the Official Compilation of Food Additives  
In June 2018, the MHLW held the first session of  the Committee on  Preparing the Tenth 
Edition of the Official Compilation of Food Additives. By February 2022, the MHLW had 
12 sessions to deliberate on the Tenth Editio n of the Official Compilation of Food 
Additives. Based on the results of the discussion s, the MHLW invited opinions  on revision of specification and standards of foods and food additives. Considering the 
opinions , the MHLW prepared the draft of the Tenth E dition of the Official Compilation 
of Food Additives . (For details, see Attachment.)  Also, based on  the consideration, some 
specifications and standards have already been published as Addend a 1 and 2 to the 
Ninth Edition.  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Attachment  
 
 
Outline of the Draft Tenth Edition of the Official Compilation of Food Additives  
 
 
1.  Establish specifications for 45 existing food additives.  
Annex 1. Substances for which specifications are to be newly established  
2.  Concerning some monographs for which one monograph applies to plural similar 
substances with different specifications according to the form or constituent, specify 
each substance as an independent monograph by separating them. The modification 
is targeted at 2 designated additives, 5 existing food additives, and 2 food additive 
preparations.  
Annex 2.  Substances for which specificatio ns are to be in dividually established 
according to the form and constituent  
3.  Modify specif ications for 105 designated additives (128 specification  categories ), 59 
existing additives (86 specification  categories ), and 2 food additive preparations  (3 
specification  categories ). Th is is to improve test ing procedures , increase the testing 
accuracy, and change regents to be used. In add ition, this is to align descript ions—
including substance names, structural formulae, terms, examples, and calculation 
formulae —with t hose based on the IUPAC (International Union  of Pure and Applied 
Chemistry ) nomenclature . 
   Annex 3.  Substances for wh ich specifications are to be modified  
4.  In section B “General Tests,” specify new testing methods including “Elemental 
Analysis” in the wake of the development of science and technology. Modify 16 existing 
testing methods stipulated in the section. This is  to improve testing techniques, to 
change regents and test apparatus  used, and to unify the wordings and descriptions.  
Also delete  “Methoxy Determination ” because there are no longer substances that 
requi re this testing method . 
 
5. In section C  “Reagents, Solutions, and Other Reference Mate rials,”  add new regents 
in line with the establishment of new testing methods and compositional specifications . 
In addition, change description  items for consistency of the description of specifications 
for regents, including addition, modification, or del etion of items.  
   
6.  Delete infrared reference spectra in section C “Reagents, Solutions, and Other 
Reference Materials,” and specify each reference spectrum in the corresponding 
monograph in section D “Monographs.”  
 7.  In sections E “Standards for Manufacturing” and F “Standards for Use,” delete the 
words  “sand ” to make specifications more accurate. And clearly represent the nam es of 
all the substance s covered by the words “ any other similar water -insoluble mineral 
substan ce.” 
 English Japanese 
Agrobacterium Succinoglycan アグロバクテリウムスクシノグリカン
Artemisia Seed Gum サバクヨモギシードガム
Aspergillus Terreus Glycoprotein アスペルギルステレウス糖たん白質
Branched Cyclodextrin 分岐シクロデキストリン
Calcinated Coral Calcium 造礁サンゴ焼成カルシウム
Calcinated Sea Urchin Shell Calcium うに殻焼成カルシウム
Calcinated Whey Calcium 乳清焼成カルシウム
Cane Wax サトウキビロウ
Capsicum Water-soluble Extract トウガラシ水性抽出物
Carpophore Derived Mannentake Extract (Fruiting body) レイシ抽出物
Chicle チクル
Coffee Bean Extract (Paste, Liquid) 生コーヒー豆抽出物（ペースト品、液体品）
Crude Potassium Chloride (Sea Water) 粗製海水塩化カリウム
Elemi Resin エレミ樹脂
Enzymatically Hydrolyzed Guar Gum グァーガム酵素分解物
Enzymatically Modified Lecithin 酵素処理レシチン
Essential Oil Removed Fennel Extract 精油除去ウイキョウ抽出物
Gallic Acid 没食子酸
Gentian Root Extract ゲンチアナ抽出物
Glucosamine グルコサミン
Heptane ヘプタン
Horseradish Extract セイヨウワサビ抽出物
Hyaluronic Acid ヒアルロン酸
Jamaica Quassia Extract ジャマイカカッシア抽出物
Japan Wax モクロウ
Jelutong ジェルトン
Licorice Oil Extract カンゾウ油性抽出物
Mevalonic Acid メバロン酸
Myrrh ミルラ
Phytin (Extract) フィチン（抽出物）
Quercetin クエルセチン
Rice Bran Wax コメヌカロウ
Rosemary Extract (Water Insoluble) ローズマリー抽出物（非水溶性）
Rosemary Extract (Water Soluble) ローズマリー抽出物（水溶性）
Rosin ロシン
Rumput Roman Extract カワラヨモギ抽出物
Sandalwood Red シタン色素
Shellac Wax シェラックロウ
Smoke Flavourings / Wood Vinegar / Liquid Smoke くん液
Sodium Chloride-decreased Brine (Saline Lake) 塩水湖水低塩化ナトリウム液
Spice Extracts 香辛料抽出物
Tea Extract チャ抽出物
Trehalose トレハロース
Urushi Wax ウルシロウ
Vegetable Carbon Black 植物炭末色素Annex 1.  Substances for which specifications are to be newly established 
Substance NameEnglish Japanese Existing
 AdditiveDesignated
AdditivePreparation English Japanese English Japanese English Japanese
Annatto Extract アナトー色素 ✔ Annatto Extract (Norbixin) アナトー色素（ノルビキシン） Annatto Extract (Bixin) アナトー色素（ビキシン）
Asparaginase アスパラギナーゼ ✔Asparaginase
 (A. niger  ASP-72-derived)アスパラギナーゼ
（A. niger ASP-72株由来）Asparaginase
(A. oryzae  NZYM-SP-derived)アスパラギナーゼ
（A. oryzae NZYM-SP株由来）
Baking Powder 合成膨張剤 ✔ Baking Powder (Single) 合成膨張剤（一剤式） Baking Powder (Duplex) 合成膨張剤（二剤式） Baking Powder (Ammonia) 合成膨張剤（アンモニア系）
Ion Exchange Resin イオン交換樹脂 ✔ Ion Exchange Resin (granule) イオン交換樹脂（粒状） Ion Exchange Resin (powder) イオン交換樹脂（粉状） Ion Exchange Resin (suspension) イオン交換樹脂（懸濁液）
Kansui かんすい ✔ Kansui (Solid) かんすい（固形） Kansui (Liquid) かんすい（液状） Kansui (Diluted Powder) かんすい（希釈粉末）
Licorice Extract カンゾウ抽出物 ✔ Licorice Extract (Crude) カンゾウ抽出物（粗製物） Licorice Extract (Purified) カンゾウ抽出物（精製物）
Phytic Acid フィチン酸 Phytic Acid (Liquid) フィチン酸（液体品） Phytic Acid (Powder) フィチン酸（粉末品）
Shellac シェラック ✔ Shellac (White Shellac) シェラック（白シェラック） Shellac (Purified Shellac) シェラック（精製シェラック）
Vegetable Sterol 植物性ステロール ✔Vegetable Sterol
(High Concentration Free Sterol)植物性ステロール
（遊離体高濃度品）Vegetable Sterol
(Low Concentration Free Sterol)植物性ステロール
（遊離体低濃度品）Substance Name Substance CategoryAnnex 2.  Substances for which specifications are to be individually established according to the form and constituent  
Substances with Independent Specifications in the 10th EditionEnglish JapaneseExisting
 AdditiveDesignated
AdditivePreparation Definition Content Description Identification Purity Assay Other
Acetone アセトン ✔ ✔
Active Carbon 活性炭 ✔ ✔
Adipic Acid アジピン酸 ✔ ✔
Alginic Acid アルギン酸 ✔ ✔
Aluminium Ammonium Sulfate 硫酸アルミニウムアンモニウム ✔ ✔
Aluminium Potassium Sulfate 硫酸アルミニウムカリウム ✔ ✔
L-Arabinose Ｌ－アラビノース ✔ ✔
L-Arginine L-Glutamate Ｌ－アルギニンＬ－グルタミン酸塩 ✔ ✔
L-Ascorbic Acid Ｌ－アスコルビン酸 ✔ Specific Rotation
L-Ascorbyl Palmitate Ｌ－アスコルビン酸パルミチン酸エステル ✔ ✔
L-Ascorbyl Stearate Ｌ－アスコルビン酸ステアリン酸エステル ✔ ✔
Aspartame アスパルテーム ✔ ✔
Bees Wax ミツロウ ✔ ✔
Calcinated Bone Calcium 骨焼成カルシウム ✔ ✔
Calcinated Eggshell Calcium 卵殻焼成カルシウム ✔ ✔
Calcinated Shell Calcium 貝殻焼成カルシウム ✔ ✔
Calcium Acetate 酢酸カルシウム ✔ ✔
Calcium Carbonate II 炭酸カルシウムⅡ ✔ ✔
Calcium Carbonate I 炭酸カルシウムⅠ ✔ ✔
Calcium Carboxymethylcellulose カルボキシメチルセルロースカルシウム ✔ ✔
Calcium Chloride 塩化カルシウム ✔ ✔
Calcium Hydroxide 水酸化カルシウム ✔ ✔
Calcium Lactate 乳酸カルシウム ✔ ✔
Calcium L-Ascorbate Ｌ－アスコルビン酸カルシウム ✔ Specific Rotation
Calcium Oxide 酸化カルシウム ✔ ✔
Calcium Propionate プロピオン酸カルシウム ✔ ✔
Calcium Silicate ケイ酸カルシウム ✔ ✔ ✔ Loss on Ignition
Calcium Stearoyl Lactylate ステアロイル乳酸カルシウム ✔ ✔
Calcium Sulfate 硫酸カルシウム ✔ CAS Registry Number 
Caramel III (Ammonia caramel) カラメルⅢ ✔ ✔
Caramel I  (Plain caramel) カラメルⅠ ✔ ✔
Caramel II (Sulfite caramel) カラメルⅡ ✔ ✔
Carbon Dioxide 二酸化炭素 ✔ ✔
Carob Bean Gum / Locust Bean Gum カロブビーンガム ✔ ✔
Chinese Bayberry Extract ヤマモモ抽出物 ✔ ✔Substance Category Substance NameAnnex 3.  Substances for which specifications are to be modified 
Category of the Specifications to Be RevisedEnglish JapaneseExisting
 AdditiveDesignated
AdditivePreparation Definition Content Description Identification Purity Assay OtherSubstance Category Substance Name Category of the Specifications to Be Revised
Chlorous Acid Water 亜塩素酸水 ✔ ✔
Citric Acid クエン酸 ✔ ✔
Cochineal Extract / Carminic Acid コチニール色素 ✔ ✔ ✔ ✔ Color Value
Curcumin / Turmeric Oleoresin ウコン色素 ✔ Substance Name
Cyanocobalamin シアノコバラミン ✔ ✔
L-Cysteine Monohydrochloride Ｌ－システイン塩酸塩 ✔ ✔
Dextranase デキストラナーゼ ✔ Dextranase Activity Test
Diluted Benzoyl Peroxide 希釈過酸化ベンゾイル ✔ ✔
Disodium DL-Tartrate ＤＬ－酒石酸ナトリウム ✔Structural Formula
Chemical Name
Disodium L-Tartrate Ｌ－酒石酸ナトリウム ✔ ✔
Enju Extract / Japanese Pagoda Tree Extract エンジュ抽出物 ✔ ✔ ✔ Substance Name
Enzymatically Decomposed Lecithin 酵素分解レシチン ✔ ✔
Erythorbic Acid エリソルビン酸 ✔ Specific Rotation
Ethyl Acetate 酢酸エチル ✔ ✔ ✔ ✔Refractive Index
Specific Gravity
Ferric Ammonium Citrate クエン酸鉄アンモニウム ✔ ✔
Ferric Chloride 塩化第二鉄 ✔ ✔ ✔
Ferric Citrate クエン酸鉄 ✔ ✔
Ferric Pyrophosphate ピロリン酸第二鉄 ✔ ✔
Ferric Pyrophosphate Solution ピロリン酸第二鉄液 ✔ ✔
Ferrous Gluconate グルコン酸第一鉄 ✔ ✔
Ferrous Sulfate 硫酸第一鉄 ✔ ✔
Gellan Gum ジェランガム ✔ ✔
Glycerol グリセリン ✔ ✔
Grape Skin Extract / Grape Skin Color ブドウ果皮色素 ✔ ✔
Guar Gum グァーガム ✔ ✔
Heme Iron ヘム鉄 ✔ ✔
Higher Fatty Acid (Behenic Acid) 高級脂肪酸（ベヘニン酸） ✔ ✔ ✔
Higher Fatty Acid (Lauric Acid) 高級脂肪酸（ラウリン酸） ✔ ✔ ✔
Higher Fatty Acid (Myristic Acid) 高級脂肪酸（ミリスチン酸） ✔ ✔ ✔
Higher Fatty Acid (Stearic Acid) 高級脂肪酸（ステアリン酸） ✔ ✔ ✔
Higher Fatty Acid (Capric Acid) 高級脂肪酸（カプリン酸） ✔ ✔ ✔
Higher Fatty Acid (Caprylic Acid) 高級脂肪酸（カプリル酸） ✔ ✔ ✔
Higher Fatty Acid (Palmitic Acid) 高級脂肪酸（パルミチン酸） ✔ ✔ ✔
High-Test Hypochlorite 高度サラシ粉 ✔ ✔
L-Histidine Monohydrochloride Ｌ－ヒスチジン塩酸塩 ✔ CAS Registry Number 
Hydrogen Peroxide 過酸化水素 ✔ ✔
1-Hydroxyethylidene-1,1-diphosphonic Acid １－ヒドロキシエチリデン－１，１－ジホスホン酸 ✔ ✔
Hydroxypropyl Cellulose ヒドロキシプロピルセルロース ✔ ✔ ✔English JapaneseExisting
 AdditiveDesignated
AdditivePreparation Definition Content Description Identification Purity Assay OtherSubstance Category Substance Name Category of the Specifications to Be Revised
Hypobromous Acid Water 次亜臭素酸水 ✔ ✔
Hypochlorous Acid Water 次亜塩素酸水 ✔ ✔ ✔
Iron Lactate 乳酸鉄 ✔ ✔
Iron Sesquioxide 三二酸化鉄 ✔ ✔
Isopropanol イソプロパノール ✔ ✔
Lac Color ラック色素 ✔ ✔ ✔
Lecithin レシチン ✔ ✔
Luohanguo Extract ラカンカ抽出物 ✔ ✔ ✔ ✔
L-Lysine L-Aspartate Ｌ－リシンＬ－アスパラギン酸塩 ✔ ✔
Macrophomopsis Gum マクロホモプシスガム ✔ ✔
Magnesium Carbonate 炭酸マグネシウム ✔ ✔
Magnesium Silicate ケイ酸マグネシウム ✔ ✔ ✔
Magnesium Stearate ステアリン酸マグネシウム ✔ ✔
DL-Malic Acid ＤＬ－リンゴ酸 ✔ ✔
D-Mannitol Ｄ－マンニトール ✔ ✔
Marigold Color マリーゴールド色素 ✔ ✔
Methyl Cellulose メチルセルロース ✔ ✔ ✔
Microcrystalline Cellulose 微結晶セルロース ✔ ✔ pH
Mixed Tocopherols ミックストコフェロール ✔ ✔
Monascus Color ベニコウジ色素 ✔ ✔ ✔
Monascus Yellow ベニコウジ黄色素 ✔ ✔ ✔
Monocalcium Di- L-Glutamate Ｌ－グルタミン酸カルシウム ✔ Water Content
Monomagnesium Di- L-Glutamate Ｌ－グルタミン酸マグネシウム ✔ Water Content
Mustard Extract カラシ抽出物 ✔ ✔ ✔ ✔ Molecular Weight 
Naringin ナリンジン ✔ ✔
Natamycin ナタマイシン ✔ Water Content
Nisin ナイシン ✔ Microbial Limits
Non-calcinated Coral Calcium サンゴ未焼成カルシウム ✔ ✔ ✔
Oxalic Acid シュウ酸 ✔ ✔
Pectin ペクチン ✔ ✔
Pectinase ペクチナーゼ ✔ Pectinase Activity Test
Peracetic Acid Composition 過酢酸製剤 ✔ ✔ ✔
ο-Phenylphenol オルトフェニルフェノール ✔ ✔
Phytic Acid (Liquid) フィチン酸　液体品 ✔ ✔
Polyisobutylene ポリイソブチレン ✔ ✔
Potassium Bromate 臭素酸カリウム ✔ ✔ ✔
Potassium Chloride 塩化カリウム ✔ ✔
Potassium Hydroxide 水酸化カリウム ✔ ✔ ✔
Potassium Hydroxide Solution 水酸化カリウム液 ✔ ✔ ✔
Potassium Lactate 乳酸カリウム ✔ ✔
Potassium Pyrosulfite ピロ亜硫酸カリウム ✔ Substance NameEnglish JapaneseExisting
 AdditiveDesignated
AdditivePreparation Definition Content Description Identification Purity Assay OtherSubstance Category Substance Name Category of the Specifications to Be Revised
Potassium Sorbate ソルビン酸カリウム ✔ ✔ ✔
Potassium Sulfate 硫酸カリウム ✔ ✔
Powdered Cellulose 粉末セルロース ✔ ✔
Preparations of Tar Colors タール色素の製剤 ✔ ✔
Propiconazole プロピコナゾール ✔ Structural Formula
Propionic Acid プロピオン酸 ✔ ✔ ✔
Propylene Glycol プロピレングリコール ✔ ✔
Propylene Glycol Alginate アルギン酸プロピレングリコールエステル ✔ ✔
Pullulan プルラン ✔ ✔
Purified Carrageenan / Refined Carrageenan 精製カラギナン ✔ ✔
L-Rhamnose Ｌ－ラムノース ✔ ✔
Rhamsan Gum ラムザンガム ✔ ✔
Riboflavin リボフラビン ✔ Specific Rotation
Riboflavin 5´-Phosphate Sodium リボフラビン５ ´－リン酸エステルナトリウム ✔ ✔
Semirefined Carrageenan / Processed Eucheuma Algae /
Processed Red Algae加工ユーケマ藻類 ✔ ✔
Silicon Dioxide (fine) 微粒二酸化ケイ素 ✔ ✔
Sodium Acetate 酢酸ナトリウム ✔ ✔
Sodium Benzoate 安息香酸ナトリウム ✔ ✔
Sodium Bicarbonate 炭酸水素ナトリウム ✔ ✔
Sodium Chlorite 亜塩素酸ナトリウム ✔ ✔
Sodium Chlorite Solution 亜塩素酸ナトリウム液 ✔ ✔
Sodium Dehydroacetate デヒドロ酢酸ナトリウム ✔ ✔
Sodium DL-Malate ＤＬ－リンゴ酸ナトリウム ✔ ✔ ✔
Sodium Ferrous Citrate クエン酸第一鉄ナトリウム ✔ ✔
Sodium Hydrosulfite 次亜硫酸ナトリウム ✔ ✔
Sodium Hydroxide 水酸化ナトリウム ✔ ✔ ✔
Sodium Hydroxide Solution 水酸化ナトリウム液 ✔ ✔ ✔
Sodium Hypochlorite 次亜塩素酸ナトリウム ✔ ✔
Sodium L-Ascorbate Ｌ－アスコルビン酸ナトリウム ✔ Specific Rotation
Sodium Methoxide ナトリウムメトキシド ✔ ✔ ✔
Sodium Polyacrylate ポリアクリル酸ナトリウム ✔ ✔
Sodium Saccharin サッカリンナトリウム ✔ ✔
Sodium Selenite 亜セレン酸ナトリウム ✔ ✔
Sodium Stearoyl Lactylate ステアロイル乳酸ナトリウム ✔ ✔
Sodium Sulfate 硫酸ナトリウム ✔ ✔
Sodium ο-Phenylphenate オルトフェニルフェノールナトリウム ✔ ✔English JapaneseExisting
 AdditiveDesignated
AdditivePreparation Definition Content Description Identification Purity Assay OtherSubstance Category Substance Name Category of the Specifications to Be Revised
D-Sorbitol Ｄ－ソルビトール ✔ ✔
DL-Tartaric Acid ＤＬ－酒石酸 ✔Structural Formula
Chemical Name
Terpineol テルピネオール ✔ ✔
Thaumatin タウマチン ✔ ✔
DL-Threonine ＤＬ－トレオニン ✔ ✔
Thujaplicin (Extract) / Hinokitiol (Extract) ツヤプリシン（抽出物） ✔ Residue on Ignition
Titanium Dioxide 二酸化チタン ✔ ✔ Loss on Ignition
Tripotassium Phosphate リン酸三カリウム ✔ ✔
Vegetable Sterol  (High Concentration Free Sterol) 植物性ステロール（遊離体高濃度品） ✔ ✔
Vegetable Sterol  (Low Concentration Free Sterol) 植物性ステロール（遊離体低濃度品） ✔ ✔
Vegetable Tannin 植物タンニン ✔ ✔ ✔
Welan Gum ウェランガム ✔ ✔
Xanthan Gum キサンタンガム ✔ ✔ Ash
Xylanase キシラナーゼ ✔ Xylanase Activity Test
D-Xylose Ｄ－キシロース ✔ ✔ ✔ ✔
Yucca Foam Extract ユッカフォーム抽出物 ✔ ✔ ✔