G/SPS/N/CAN/1531  
20 September 2023  
(23-6258) Page: 1/2 
Committee on Sanitary and Phytosanitary Measures  Original: English/French  
 
  NOTIFICATION  
1. Notifying Member:  CANADA  
If applicable, name of local government involved:   
2. Agency responsible:  Health Canada  
3. Products covered (provide tariff item number(s) as specified in national 
schedules deposited with the WTO; ICS numbers should be provided in addition, 
where applicable):  Lipase from S accharomyces cerevisiae  LALL-LI in bread, flour, whole 
wheat flour and unstandardized bakery products (ICS Codes: 67.220.20, 67.060)  
4. Regions or countries likely to be affected, to the extent relevant or practicable : 
[X] All trading partners   
[ ] Specific regions or countries:   
5. Title of the notified document:  Notice of modification to the List of Permitted Food 
Enzymes  to enable the use of lipase from Saccharomyces c erevisiae  LALL-LI in bread, 
flour, whole wheat flour and unstandardized bakery products . Language(s):  English and 
French . Number of pages:  3 
https://members.wto.org/crnattachments/2023/SPS/CAN/23_12503_00_e.pdf  
https://members.wto.org/crnattachments/2023/SPS/CAN/23_12503_00_f.pdf  
6. Description of content:  Health Canada's Food Directo rate completed a premarket safety 
assessment of a food additive submission seeking approval for the use of lipase from 
Saccharomyces cerevisiae  LALL-LI in bread, flour, whole wheat flour and unstandardized 
bakery products.  
Lipase from other sources is alre ady permitted for use in Canada in the foods requested by 
the petitioner. However, prior to this Notice, the source organism, S. cerevisiae  LALL-LI, 
was not a permitted source for any food enzyme in Canada.  
The results of the premarket assessment support t he safety of lipase from S. cerevisiae  
LALL-LI for its requested uses. Consequently, Health Canada has enabled the use of lipase 
from S. cerevisiae  LALL-LI as described in the information document by modifying the 
List of Permitted Food Enzymes , effective September 13, 2023.  
The purpose of the information document is to publicly announce the Department's 
decision in this regard and to provide the appropriate contact information for those wishing 
to submit an inquiry or new scientific information relevant to  the safety of this food 
additive.  
7. Objective and rationale: [X]  food safety, [  ] animal health, [  ] plant protection, 
[ ] protect humans from animal/plant pest or disease, [  ] protect territory from 
other damage from pests.   G/SPS/N/CAN/1531  
 
- 2 - 
 
  8. Is there a relevant international standard? If so, identify the standard:  
[ ] Codex Alimentarius Commission (e.g.  title or serial number of Codex 
standard or related text) :  
[ ] World Organization for Animal Health (OIE) (e.g.  Terrestrial or Aquatic 
Animal Health Cod e, chapter number) :  
[ ] International Plant Protection Convention (e.g.  ISPM number) :  
[X] None  
Does this proposed regulation conform to the relevant international standard?  
[ ] Yes   [  ] No 
If no, describe, whenever possible, how and why it deviates fro m the 
international standard:   
9. Other relevant documents and language(s) in which these are available:  Health 
Canada's Food and Nutrition – 'Public Involvement and Partnerships' Web site, posted 
September 13, 2023  (available in English and French):  
https://www.canada.ca/en/health -canada/services/food -nutrition/public -involvement -
partnerships.html  (English)  
https://www.canada.ca/fr/sante -canada/services/aliments -nutrition/participation -public -
partenariats.html  (French)   
10. Proposed date of adoption (dd/mm/yy) : 13 September 2023  
Proposed date of publication (dd/mm/yy) :  
11. Proposed date of entry into force: [  ] Six months from date of publication , and/or  
(dd/mm/yy) : 13 September 2023  
[ ] Trade facilitating measure   
12. Final date for comments: [  ] Sixty days from the date of circulation of the 
notification and/or (dd/mm/yy) : 26 November 2023  
Agency or authority designated to handle comments: [  ] National Notification 
Authority, [X]  Nation al Enquiry Point. Address, fax number and e -mail address (if 
available) of other body:   
13. Text(s) available from: [  ] National Notification Authority, [X]  National Enquiry 
Point. Address, fax number and e -mail address (if available) of other body:   
The "Notice of modification to the List of Permitted Food Enzymes to enable the use of 
lipase from Saccharomyces cerevisiae LALL -LI in bread, flour, whole wheat flour and 
unstandardized bakery products " is available through the following weblink:  
https://www.canada.ca/en/health -canada/services/food -nutrition/public -involvement -
partnerships/notice -modification -list-permitted -food-enzymes -enable -use-lipase -
saccharomyces -cerevisiae -lall-li-bread -flour-whole -wheat -unstandardized -bakery -
products.html  (English)  
https://www.canada.ca/fr/sante -canada/services/aliments -nutrition/participation -public -
partenariats/avis -modification -liste-enzymes -alimentaires -autorisees -permettr e-utilisation -
lipase -issue-saccharomyces -cerevisiae -lall-li-farine -ble-entier -pain-produits -boulangerie -
non-normalises.html  (French)  
Canada's Notification Authority and Enquiry Point  
Technical Barriers and Regulations Division  
Global Affairs Canada 111, promenade Sussex Drive  
Ottawa, ON K1A 0G2  
Canada  
Tel: +(343) 203 4273  
Fax: +(613) 943 0346  
E-mail: enquirypoint@international.gc.ca