Notified document - Proposed GB mandatory classification and labelling (GB MCL) of 48 hazardous chemical substance s – March 2024  
1 
 International Chemical Identification and 
link to Agency Opinion  EC No.  CAS No.  Classification  Labelling  Specific 
Concentration 
Limits, M -factor  Notes  
Hazard Class 
and Category 
Code(s)  Hazard 
Statement 
Code(s)  Pictogram, 
Signal Word 
Code(s)  Hazard 
Statement 
Code(s)  Suppl. 
Hazard 
Statement 
Code(s)  
Nonylphenol, branched and linear, 
ethoxylated (with average molecular weight 
< 352 g/mol) [includes orthometa -, para - 
isomers or any combination thereof]   500-315-8  
500-024-6  
500-045-0  
500-209-1  
248-762-5  
243-816-4 
248-291-5 
687-833-9  
and others  127087 -87-0  
9016 -45-9 
26027 -38-3 
68412 -54-4 
27986 -36-3  
20427 -84-3 
27176 -93-8 
1119449 -38-5 
and others  Aquatic Acute 1  
Aquatic Chronic 1  H400  
H410  GHS09  
Wng  H410   M = 1  
M = 10   
Nonylphenol, branched and linear, 
ethoxylated (with 352 g/mol ≤ average 
molecular weight < 704 g/mol) [includes 
ortho -, meta -, para - isomers or any 
combination thereof]  230-770-5  
248-743-1  
247-555-7  
248-293-6  
and others  127087 -87-0 
9016 -45-9 
7311 -27-5 
27942 -27-4 
26264 -02-8 
27177 -05-5 
14409 -72-4  
and others  Aquatic Acute 1  
Aquatic Chronic 1  H400  
H410  GHS09  
Wng  H410   M = 1  
M = 10   
Nonylphenol, branched and linear, 
ethoxylated (with 704 g/mol ≤ average 
molecular weight ≤ 1540 g/mol) [includes 
ortho -, meta -, para - isomers or any 
combination thereof]   - 127087 -87-0 
9016 -45-9  
and others  Aquatic Acute 1  
Aquatic Chronic 1  H400  
H410  GHS09  
Wng  H410   M = 1  
M = 10   
Hydrogen sulphide, hydrogen sulfide  231-977-3 7783 -06-4 Press. Gas  
Flam. Gas 1A  
Acute Tox. 2  
Aquatic Acute 1  H220  
H330  
H400  GHS02 
GHS06 
GHS09  
Dgr  H220  
H330  
H400   Inhalation: ATE = 
440 ppmV 
(gases)  U  
1-phenylethan -1-one (1 -
phenylethylidene)hydrazone  211-979-0 729-43-1 Skin Sens.1  H317  GHS07  
Wng  H317     
Diuron  (ISO)  206-354-4 330-54-1 Carc. 1B  
STOT RE 2  
Aquatic Acute 1  
Aquatic Chronic 1  H350  
H373 (blood 
system)  
H400  
H410  GHS08 
GHS09  
Dgr  H350  
H373 (blood 
system)  
H410   M = 100  
M = 100   
Diphenyl(2,4,6 -trimethylbenzoyl)phosphine 
oxide  278-355-8 75980 -60-8 Skin Sens. 1B 
Repr. 1B  H317 
H360Fd  GHS08 
GHS07  
Dgr  H317  
H360Fd     
Clothianidin  (ISO)  433-460-1 210880 -92-5 Repr. 2  
Acute Tox. 4  
STOT SE 1  
Aquatic Acute 1  
Aquatic Chronic 1  H361f  
H302  
H370 
(nervous 
system)  
H400  
H410  GHS07 
GHS08 
GHS09  
Dgr  H361f  
H302  
H370 
(nervous 
system)  
H410   Oral: ATE  = 390 
mg/kg bw  
M = 10  
M = 100   
Benzyl alcohol  202-859-9 100-51-6 Acute Tox. 4  
Eye Irrit. 2  
Skin Sens. 1B  H302  
H319  
H317  GHS07  
Wng  H302  
H319  
H317   Oral: ATE = 1200 
mg/kg bw   Notified document - Proposed GB mandatory classification and labelling (GB MCL) of 48 hazardous chemical substance s – March 2024  
2 
 International Chemical Identification and 
link to Agency Opinion  EC No.  CAS No.  Classification  Labelling  Specific 
Concentration 
Limits, M -factor  Notes  
Hazard Class 
and Category 
Code(s)  Hazard 
Statement 
Code(s)  Pictogram, 
Signal Word 
Code(s)  Hazard 
Statement 
Code(s)  Suppl. 
Hazard 
Statement 
Code(s)  
Dimethyl propylphosphonate  242-555-3  18755 -43-6 Muta 1B  
Repr 1B  H340 
H360Df  GHS08  
Dgr  H340  
H360Df     
Resorcinol ; 1,3-benzenediol   203-585-2 108-46-3 Acute Tox. 4  
STOT SE 1  
Skin Irrit. 2  
Eye Irrit. 2  
Skin Sens. 1B  
Aquatic Acute 1  H302  
H370 
(nervous 
system) 
H315  
H319  
H317  
H400  GHS07 
GHS08 
GHS09  
Dgr  H315  
H319  
H317  
H400   Oral: ATE = 500 
mg/kg bw  
M = 1   
9-[2-(ethoxycarbonyl)phenyl] -3,6-
bis(ethylamino) -2,7-dimethylxanthylium 
chloride; Basic Red 1  213-584-9 989-38-8 Acute Tox. 3  
Eye Dam. 1  
Skin Sens. 1 
Aquatic Acute 1 
Aquatic Chronic 1  H301  
H318  
H317  
H400  
H410  GHS05 
GHS06 
GHS09  
Dgr H301  
H318  
H410   Oral ATE = 280 
mg/kg bw  
M = 10  
M = 1   
Picolinafen  (ISO)   137641 -05-5 STOT RE 2 
Aquatic Acute 1 
Aquatic Chronic 1  H373 (blood 
system, 
thyroid)  
H400  
H410  GHS08  
GHS09  
Wng  H373 (blood 
system, 
thyroid)  
H410   M = 1000  
M = 1000   
Dibutyltin maleate  201-077-5 78-04-6 Muta. 2  
Repr. 1B  
Acute Tox. 2  
Acute Tox. 4  
STOT RE 1  
Skin Corr. 1  
Eye Dam. 1  H341 
H360FD 
H330  
H302  
H372 
(immune 
system)  GHS08 
GHS06 
GHS05  
Dgr H314  
H318  
H341  
H360FD 
H330  
H302  
H372 
(immune 
system)   Inhalation: ATE = 
0.317 mg/L 
(dusts or  mists)  
Oral: ATE = 510 
mg/kg bw   
Dibutyltin oxide  212-449-1 818-08-6 Muta. 2  
Repr. 1B  
Acute Tox. 3  
STOT RE 1  
Skin Irrit. 2  
Eye Dam 1  H341  
H360FD  
H301  
H372 
(immune 
system)  
H315  
H318  GHS08  
GHS06  
GHS05  
Dgr  H341 
H360FD 
H301  
H372 
(immune 
system)  
H315  
H318   Oral: ATE = 170 
mg/kg bw   
Cymoxanil  (ISO) 261-043-0 57966 -95-7 Repr. 2  
Acute Tox. 4  
STOT RE 2  
Skin Sens. 1  
Aquatic Acute 1  
Aquatic Chronic 1  H361fd  
H302  
H317  
H373 (blood 
system, 
thymus, 
eyes)  
H400  
H410  GHS08 
GHS07 
GHS09  
Wng  H361fd  
H302  
H317  
H373 (blood 
system, 
thymus, eyes)  
H410   Oral: ATE = 360 
mg/kg bw  
M = 1  
M = 1   Notified document - Proposed GB mandatory classification and labelling (GB MCL) of 48 hazardous chemical substance s – March 2024  
3 
 International Chemical Identification and 
link to Agency Opinion  EC No.  CAS No.  Classification  Labelling  Specific 
Concentration 
Limits, M -factor  Notes  
Hazard Class 
and Category 
Code(s)  Hazard 
Statement 
Code(s)  Pictogram, 
Signal Word 
Code(s)  Hazard 
Statement 
Code(s)  Suppl. 
Hazard 
Statement 
Code(s)  
Tetrabromobisphenol -A (TBBPA)  201-236-9 79-94-7 Carc 1B  
Aquatic Acute 1  
Aquatic Chronic 1  H350  
H400  
H410  GHS08 
GHS09  
Dgr  H350  
H410     
Sulphur dioxide  231-195-2 7446 -09-5 Press. Gas  
Acute Tox. 3  
Skin. Corr. 1B  
STOT SE 1  H331  
H314  
H370 
(respiratory 
system, 
inhalation)  GHS04 
GHS05 
GHS06 
GHS08  
Dgr  H331  
H314  
H370 
(respiratory 
system, 
inhalation)   Inhalation: ATE = 
1000 ppmV 
(gases)   U, 5 
Methyl 5 -(2,4-dichlorophenoxy) -2-
nitrobenzoate; bifenox  255-894-7 42576 -02-3 Acute Tox. 4 
Aquatic Acute 1 
Aquatic Chronic 1  H302  
H400  
H410  GHS07 
GHS09  
Wng  H302  
H410   M = 1000  
M = 1000   
1,2-benzisothiazol -3(2H) -one; 1,2 -
benzisothiazolin -3-one 220-120-9 2634 -33-5 Acute Tox . 2  
Acute Tox. 4  
Skin Irrit. 2  
Eye Dam. 1  
Skin Sens. 1A  
Aquatic Acute 1  
Aquatic Chronic 1  H330  
H302  
H315  
H318  
H317  
H400  
H410  GHS06 
GHS05 
GHS09  
Dgr  H330  
H302  
H315  
H318  
H317  
H410   Oral: ATE = 450 
mg/kg bw 
Inhalation: ATE = 
0.21 mg/L (dusts 
or mists)  
Skin Sens. 1A; 
H317: C≥0.036%  
M = 1  
M = 1   
1,4-Benzenediamine, N,N' -mixed Ph and 
tolyl derivs.; Reaction mass of N -phenyl,N’ -
o-tolyl-phenylene diamine, N,N’ -diphenylp -
phenylene diamine and N,N’ -di-o-tolyl-
phenylene diamine  273-227-8 68953 -84-4 Skin Sens. 1 
Repr. 1B  H317 
H360FD  GHS07 
GHS08  
Dgr  H317 
H360FD     
4-methylimidazole  212-497-3 822-36-6 Carc. 1B  
Repr. 1B  H350 
H360Fd  GHS08  
Dgr  H350  
H360Fd     
3,3,4,4,5,5,6,6,7,7,8,8,8 -tridecafluorooctan -
1-ol 211-477- 1 647-42-7 STOT RE 2 
Aquatic Chronic 1  H373  
(teeth, 
bones)  
H410  GHS08 
GHS09  
Wng  H373  
(teeth,  bones )  
H410   M = 1  
Tetramethylene dimethacrylate  218-218-1 2082 -81-7 Skin Sens. 1B  H317  GHS07  
Wng  H317     
7,7,9(or 7,9,9) -trimethyl -4,13-dioxo -3,14-
dioxa -5,12- diazahexadecane -1,16-diyl 
bismethacrylate  276-957-5 72869 -86-4 Skin Sens. 1B  H317  GHS07  
Wng  H317     
2,2'-ethylenedioxydiethyl dimethacrylate  203-652-6 109-16-0 Skin Sens. 1B  H317  GHS07  
Wng  H317     
2,2'-[[3-methyl -4-[(4-
nitrophenyl)azo]phenyl]imino]bisethanol  221-665-5 3179 -89-3 Skin Sens. 1B  H317  GHS07  
Wng  H317     
Benalaxyl  275-728-7 71626 -11-4 Acute Tox. 4 
Aquatic Acute 1 
Aquatic Chronic 1  H302  
H400  
H410  GHS09 
GHS07  
Wng  H302 H410   Oral; ATE = 1000 
mg/kg bw  
M = 1  
M = 1   Notified document - Proposed GB mandatory classification and labelling (GB MCL) of 48 hazardous chemical substance s – March 2024  
4 
 International Chemical Identification and 
link to Agency Opinion  EC No.  CAS No.  Classification  Labelling  Specific 
Concentration 
Limits, M -factor  Notes  
Hazard Class 
and Category 
Code(s)  Hazard 
Statement 
Code(s)  Pictogram, 
Signal Word 
Code(s)  Hazard 
Statement 
Code(s)  Suppl. 
Hazard 
Statement 
Code(s)  
Reaction mass of N,N' - ethane -1,2- 
diylbis(decanamide); 12 -hydroxy -N-[2-[(1-
oxodecyl)amino]ethyl] octadecanamide; 
N,N'-ethane -1,2- diylbis(12 -
hydroxyoctadecanamide); [1]  
N,N'-Ethane -1,2- 
diylbis(12 -hydroxyoctadecanamide)[Thixatrol 
plus] [2]  430-050-2 n/a Skin Sens. 1 
Aquatic Acute 1 
Aquatic Chronic 1  H317  
H400  
H410  GHS07 
GHS09  
Wng  H317  
H410   M = 100  
M = 10   
α-methyl -1,3-benzodioxole -5-
propionaldehyde [1]  
(S)-α-methyl -1,3-benzodioxole -5-
propionaldehyde;  
(2S)-3-(1,3-benzodioxol -5-yl)-2-
methylpropanal [2]  
(R)-α-methyl -1,3-benzodioxole -5-
propionaldehyde;  
(2R)-3-(1,3-benzodioxol -5-yl)-2-
methylpropanal [3]  214-881-6 [1] 
- [2] 
- [3] 1205 -17-0 [1]  
737776 -68-0 [2]  
737776 -59-9 [3] Skin Sens. 1B  H317  GHS07  
Wng  H317     
2-[ethyl[3 -methyl -4-[(5-nitrothiazol -2-
yl)azo]phenyl]amino]ethanol [Disperse Blue 
106] 271-183-4 68516 -81-4 Skin Sens. 1A  H317  GHS07  
Wng  H317   Skin Sens. 1A; 
H317; C ≥ 
0.001%   
Propyl 3,4,5 -trihydroxybenzoate  204-498-2 121-79-9 Acute Tox. 4  
Skin Sens. 1  
Aquatic Acute 1  
Aquatic Chronic 1  H302  
H317  
H400  
H410  GHS07  
GHS09  
Wng  H302 H410   Oral: ATE=1700 
mg/kg bw  
M = 1  
M = 1   
(3E)-dec-3-en-2-one - 18402 -84-1 Acute Tox. 4  
Skin Irrit. 2  
Aquatic Chronic 2  H332  
H315  
H411  GHS07 
GHS09  
Wng  H332 H315 
H411   Inhalation: ATE = 
1.5 mg/L (dusts 
or mists)   
Acetone oxime  204-820-1 127-06-0 Carc. 1B  
Acute Tox. 4 
STOT SE 3 
STOT RE 2  
Eye Dam. 1  
Skin Sens. 1  H350  
H312  
H336  
H373 (blood 
system)  
H318  
H317  GHS08 
GHS07 
GHS05  
Dgr  H350  
H312  
H336  
H373 (blood 
system)  
H318  
H317   Dermal: ATE = 
1100 mg/kg bw   
Benthiavalicarb -isopropyl  (ISO)  - 177406 -68-7 Carc. 1B  
Repr. 2  
Skin Sens. 1  
Aquatic Chronic 2  H350  
H361d  
H317  
H411  GHS08 
GHS07 
GHS09  
Dgr  H350 H361d 
H317  
H411     
2,3-epoxypropyl neodecanoate  247-979-2 26761 -45-5 Skin Sens. 1A 
Muta. 2  H317  
H341  GHS07 
GHS08  
Wng  H317  
H341   Skin Sens. 1A; 
H317: C ≥ 
0.001%   
Multi -Walled Carbon Tubes (synthetic 
graphite in tubular shape) with a geometric 
tube diameter range ≥ 30 nm to < 3 μm and 
a length ≥  - - Carc. 1B  
STOT RE 1  H350i  
H372 (lung) 
(inhalation)  GHS08  
Dgr  H350i  
H372 (lung) 
(inhalation)   STOT RE 1; 
H372  
(lung)(inhalation): 
C ≥ 1 %   Notified document - Proposed GB mandatory classification and labelling (GB MCL) of 48 hazardous chemical substance s – March 2024  
5 
 International Chemical Identification and 
link to Agency Opinion  EC No.  CAS No.  Classification  Labelling  Specific 
Concentration 
Limits, M -factor  Notes  
Hazard Class 
and Category 
Code(s)  Hazard 
Statement 
Code(s)  Pictogram, 
Signal Word 
Code(s)  Hazard 
Statement 
Code(s)  Suppl. 
Hazard 
Statement 
Code(s)  
5 μm and aspect ratio > 3:1, including Multi -
Walled Carbon Nanotubes, MWC(N)T  
 STOT RE 2; 
H373 (lung):  
0.1 % ≤ C< 1 %  
Hexyl salicylate  228-408-6 6259 -76-3 Skin Sens. 1 
Repr. 2  H317  
H361d  GHS07 
GHS08 Wng  H317  
H361d     
7-oxabicyclo[4.1.0]hept -3-ylmethyl 7 -
oxabicyclo[4.1.0]heptan -3-carboxylate  219-207-4 2386 -87-0 Skin Sens. 1 
Muta. 2  
STOT RE 2  H317  
H341  
H373 (nasal 
cavity)  GHS07 
GHS08  
Wng  H317  
H341  
H373 (nasal 
cavity)     
Tetrasodium 4 -amino -5-hydroxy -3,6-bis[[4 -
[[2- (sulphonatooxy)ethyl]sulphonyl] 
phenyl]azo]naphthalene -2,7- disulphonate; 
[1] and Reaction products of 4 -amino -5- 
hydroxynaphthalene -2,7-disulfonic acid, 
coupled twice with diazotized 2 -[(4-
aminophenyl)sulfonyl ]ethyl hydrogen sulfate, 
sodium salts; [2] and disodium 4 -amino -5-
hydroxy -3,6-bis{[4 - 
(vinylsulfonyl)phenyl]diazenyl}naphthalene -
2,7-disulfonate; [3]  241-164-5 [1] 
-[2] 
-[3] 17095 -24-8 [1]  
- [2] 
100556 -82-9 [3] Resp. Sens. 1A 
Skin Sens. 1  H334  
H317  GHS08  
Dgr  H334  
H317     
2-(dimethylamino) -2-[(4-
methylphenyl)methyl] -1-[4- (morpholin -4-
yl)phenyl]butan -1-one 438-340-0 119344 -86-4 Repr. 1B  
Aquatic Acute 1  
Aquatic Chronic 1  H360Df 
H400  
H410  GHS08 
GHS09  
Dgr  H360Df  
H410   M = 1  
M = 1   
Formic acid ...%  200-579-1 64-18-6 Flam. Liq. 3  
Met. Corr. 1  
Acute Tox. 4 
Acute Tox. 3  
Skin Corr. 1A  
Eye Dam. 1  H226  
H290  
H302  
H331  
H314  
H318  GHS02 
GHS05 
GHS06  
Dgr  H226  
H290 H  
302  
H331  
H314  EUH071  Flam. Liq. 3; 
H226: C > 85%  
Oral: ATE = 500 
mg/kg bw  
Inhalation: ATE = 
7.4 mg/l 
(vapours)  
Skin Corr. 1A; 
H314: C ≥ 90%  
Skin Corr. 1B;  
314: 10% ≤ C < 
90%  
Skin Irrit. 2; 
H315: 2% ≤ C < 
10%  
Eye Dam. 1; 
H318: C ≥ 10%  
Eye Irrit. 2; H319: 
2% ≤ C < 10%  B 
Dicamba  (ISO)  217-635-6 1918 -00-9 Acute Tox. 4  
Acute Tox. 4  
Eye Dam. 1  
STOT SE 3  
STOT SE 3  H332  
H302  
H318  
H335  
H336  GHS07 
GHS05 
GHS09  
Dgr  H332  
H302  
H318  
H335  
H336   Inhalation: ATE = 
4.0 mg/L  
Oral: ATE = 1500 
mg/kg bw  
M = 1   Notified document - Proposed GB mandatory classification and labelling (GB MCL) of 48 hazardous chemical substance s – March 2024  
6 
 International Chemical Identification and 
link to Agency Opinion  EC No.  CAS No.  Classification  Labelling  Specific 
Concentration 
Limits, M -factor  Notes  
Hazard Class 
and Category 
Code(s)  Hazard 
Statement 
Code(s)  Pictogram, 
Signal Word 
Code(s)  Hazard 
Statement 
Code(s)  Suppl. 
Hazard 
Statement 
Code(s)  
Aquatic Acute 1  
Aquatic Chronic 2  H400  
H411  H410  
Formaldehyde …%  200-001-8 50-00-0 Carc. 1B  
Muta. 2  
Acute Tox. 4  
Acute Tox. 2  
Skin Corr. 1B  
Skin Sens. 1A ;  H350  
H341  
H302  
H330  
H314  
H317  GHS05 
GHS06 
GHS08  
Dgr  
 H350  
H341  
H302  
H330  
H314  
H317  EUH071  
 Inhalation: ATE = 
100 ppm V 
(gases)  
Skin Corr. 1B; 
H314: C ≥ 25 %  
Skin Irrit. 2; 
H315: 5 % ≤ C < 
25 %  
Eye Irrit. 2; H319: 
5 % ≤ C < 25 %  
STOT SE 3; 
H335: C ≥ 5 %  B, D, F  
S-metolachlor  (ISO)  - 87392 -12-9 Carc. 2  
Skin Sens. 1  
Aquatic Acute 1  
Aquatic Chronic 1  H351  
H317  
H400  
H410  GHS08 
GHS07 
GHS09  
Wng  H351  
H317  
H410  EUH066  M = 10  
M = 10   
Peracetic acid …%  201-186-8 79-21-0 Org. Perox. D 
Acute Tox. 2 
Acute Tox. 2 
Acute Tox. 3  
Skin Corr. 1A  
Aquatic Acute 1  
Aquatic Chronic 1  H242  
H330  
H310  
H301  
H314  
H400  
H410  GHS02 
GHS06 
GHS05 
GHS09  
Dgr  H242  
H330  
H310  
H301  
H314  
H410  EUH071  Inhalation: ATE = 
0.2 mg/L (dusts 
and mists) 
Dermal: ATE = 
60 mg/kg bw 
Oral: ATE = 80 
mg/kg bw  
STOT SE 3; 
H335: C ≥ 1 %  
M = 10  
M = 100  B, D, T  
Ethanethiol; ethyl mercaptan  200-837-3 75-08-1 Flam. Liq. 1 
Acute Tox. 3 
Acute Tox. 4 
Aquatic Acute 1 
Aquatic Chronic 1  H224  
H331  
H302  
H400  
H410  GHS02 
GHS06 
GHS09  
Dgr  H224  
H331  
H302  
H410   Inhalation: ATE = 
7.1 mg/L 
(vapours)  
Oral: ATE = 680 
mg/kg  bw  
Trimethyl borate  204-468-9 121-43-7 Flam. Liq. 3 
Acute Tox. 4* 
Repr. 1B  H226  
H312  
H360FD  GHS02 
GHS07 
GHS08  
Dgr  H226  
H312  
H360FD