EN   EN 
 
 
 EUROPEAN  
COMMISSION   
Brussels, XXX  
SANTE/11776/2020 ANNEX  
(POOL/E4/2020/11776/11776 -EN 
ANNEX.docx)  
[…](2021) XXX  draft  
ANNEX  
 
ANNEX  
to the  
COMMISSION DELEGATED REGULATION (EU) .../...  
amending Annex II to Delegated Regulation (EU) No 1062/2014 on the work programme 
for the systematic examination of all existing active substances contained in biocidal 
products referred to in Regulation (EU) No  528/2012 of the European Parliament and of 
the Council  
  
   
EN 1  EN ANNEX  
‘ANNEX II  
SUBSTANCE/PRODUCT -TYPE COMBINATIONS INCLUDED IN THE REVIEW PROGRAMME ON [OP please insert the date of adoption ] 
Active substance/product -type combinations supported on [OP please insert the date of adoption ], excluding any other nanomaterial than th at explicitly mentioned in entr y 1017 and 
excluding any generation in situ of the active substance except when explicitly mentioned with the reference to the supported  precursor(s).  
Entry 
number  Substance name  Rapporteur 
Member 
State  EC number  CAS number  1 2 3 4 5 6 7 8 9 10 11 12 13 17 18 19 21 22 
1 Formaldehyde  DE 200-001-8 50-00-0                  x 
9 Bronopol  ES 200-143-0 52-51-7  x    x     x x      x 
36 Ethanol  EL 200-578-6 64-17-5 x x  x               
37 Formic acid  BE 200-579-1 64-18-6  x x x x x             
1025  Performic acid generated from formic acid and 
hydrogen peroxide  BE    x  x       x x       
43 Salicylic acid  NL 200-712-3 69-72-7  x x x               
52 Ethylene oxide  NO 200-849-9 75-21-8  x                 
69 Glycolic acid  NL 201-180-5 79-14-1  x x x               
1026  Peracetic acid generated from 
tetraacetylethylenediamine (TAED) and 
hydrogen peroxide  AT    x                 
1027  Peracetic acid generated from 1,3 - 
diacetyloxypropan -2-yl acetate and hydrogen 
peroxide  AT    x                 
71 L-(+)-lactic acid  DE 201-196-2 79-33-4      x             
79 (2R,6aS,12aS) -1,2,6,6a,12,12a -Hexahydro -2-
isopropenyl -8,9-dimethoxychromeno[3,4 -
b]furo[2,3 -h]chromen -6-one (Rotenone)  PL 201-501-9 83-79-4              x     
85 Symclosene  DE 201-782-8 87-90-1  x x x x      x        
92 Biphenyl -2-ol ES 201-993-5 90-43-7       x  x x         
113 3-Phenyl -propen -2-al (Cinnamaldehyde)  PL 203-213-9 104-55-2  x                 
117 Geraniol  FR 203-377-1 106-24-1               x x   
122 Glyoxal  FR 203-474-9 107-22-2  x x x               
133 Hexa -2,4-dienoic acid (Sorbic acid)  DE 203-768-7 110-44-1      x             
171 2-Phenoxyethanol  IT 204-589-7 122-99-6 x x  x  x       x      
180 Sodium dimethylarsinate (Sodium Cacodylate)  PT 204-708-2 124-65-2               x     
EN 2  EN Entry 
number  Substance name  Rapporteur 
Member 
State  EC number  CAS number  1 2 3 4 5 6 7 8 9 10 11 12 13 17 18 19 21 22 
185 Tosylchloramide sodium (Chloramin T)  ES 204-854-7 127-65-1  x x x x              
187 Potassium dimethyldithiocarbamate  SE 204-875-1 128-03-0         x  x x       
188 Sodium dimethyldithiocarbamate  SE 204-876-7 128-04-1         x  x x       
227 2-Thiazol -4-yl-1H-benzoimidazole 
(Thiabendazole)  ES 205-725-8 148-79-8       x  x x         
235 Diuron  DK 206-354-4 330-54-1       x   x         
239 Cyanamide  DE 206-992-3 420-04-2   x            x    
283 Terbutryn  SK 212-950-5 886-50-0       x  x x         
292 (1,3,4,5,6,7 -Hexahydro -1,3-dioxo -2H-isoindol -
2-yl)methyl (1R -trans) -2,2-dimethyl -3-(2-
methylprop -1-enyl)cyclopropanecarboxylate (d -
Tetramethrin)  DE 214-619-0 1166 -46-7               x    
321 Monolinuron  HU 217-129-5 1746 -81-2  x                 
330 N-(3-Aminopropyl) -N-dodecylpropane -1,3-
diamine (Diamine)  PT 219-145-8 2372 -82-9  x x x  x  x   x x x      
336 2,2'-Dithiobis[N -methylbenzamide] (DTBMA)  PL 219-768-5 2527 -58-4      x             
339 1,2-Benzisothiazol -3(2H) -one (BIT)  ES 220-120-9 2634 -33-5  x    x   x  x x x      
341 2-Methyl -2H-isothiazol -3-one (MIT)  SI 220-239-6 2682 -20-4      x             
346 Sodium dichloroisocyanurate dihydrate  DE 220-767-7 51580 -86-0  x x x x      x        
345 Troclosene sodium  DE 220-767-7 2893 -78-9  x x x x      x        
348 Mecetronium ethylsul fate (MES)  PL 221-106-5 3006 -10-8 x                  
359 Formaldehyde released from 
(Ethylenedioxy)dimethanol (Reaction products 
of ethylene glycol with paraformaldehyde 
(EGForm))  PL 222-720-6 3586 -55-8      x     x x x      
365 Pyridine -2-thiol 1 -oxide, sodium salt (Sodium 
pyrithione)  SE 223-296-5 3811 -73-2  x    x x  x x   x      
368 Methenamine 3 -chloroallylochloride (CTAC)  PL 223-805-0 4080 -31-3      x      x x      
377 2,2',2'' -(Hexahydro -1,3,5 -triazine -1,3,5 -
triyl)triethanol (HHT)  PL 225-208-0 4719 -04-4      x     x x x      
382 Tetrahydro -1,3,4,6 -
tetrakis(hydroxymethyl)imidazo[4,5 -
d]imidazole -2,5(1H,3H) -dione (TMAD)  ES 226-408-0 5395 -50-6      x     x x x      
392 Methylene dithiocyanate  FR 228-652-3 6317 -18-6            x       
393 1,3-Bis(hydroxymethyl) -5,5-
dimethylimidazolidine -2,4-dione (DMDMH)  PL 229-222-8 6440 -58-0      x       x      
397 Didecyldimethylammonium chloride (DDAC)  IT 230-525-2 7173 -51-5 x x    x    x x x        
EN 3  EN Entry 
number  Substance name  Rapporteur 
Member 
State  EC number  CAS number  1 2 3 4 5 6 7 8 9 10 11 12 13 17 18 19 21 22 
401 Silver  SE 231-131-3 7440 -22-4  x  x x      x        
405 Sulfur dioxide  generated from sulfur by 
combustion  DE      x               
424 Active bromine generated from sodium bromide 
and sodium hypochlorite  NL    x         x x       
1030  Active bromine generated from sodium bromide 
and calcium hypochlorite  NL    x         x x       
1031  Active bromine generated from sodium bromide 
and chlorine  NL    x         x x       
1032  Active bromine generated from sodium bromide 
by electrolysis  NL    x         x x       
1033  Active bromine generated from hypobromous 
acid and urea and bromourea  NL             x x       
1034  Active bromine generated from sodium 
hypobromite and N -bromosulfamate and 
sulfamic acid  NL             x        
434 Tetramethrin  DE 231-711-6 7696 -12-0               x    
439 Hydrogen peroxide  FI 231-765-0 7722 -84-1           x x       
1036  Hydrogen peroxide released from sodium 
percarbonate  FI    x x                
444 7a-Ethyldihydro -1H,3H,5H -oxazolo[3,4 -
c]oxazole (EDHO)  PL 231-810-4 7747 -35-5      x       x      
450 Silver nitrate  SE 231-853-9 7761 -88-8 x                  
453 Disodium peroxodisul fate PT 231-892-1 7775 -27-1    x               
432 Active chlorine released from s odium 
hypochlorite  IT             x x       
455 Active chlorine released from c alcium 
hypochlorite  IT             x        
457 Active chlorine released from c hlorine  IT             x        
458 Monochloramine generated from ammonium 
sulfate and a chlorine source  FR 
             x 
 x 
       
1016  Silver chloride  SE 232-033-3 7783 -90-6 x x    x x  x          
1076  Silver -polyethylen imine -chloride  SE   x x       x          
491 Chlorine dioxide  DE 233-162-8 10049 -04-4  x x x x      x x       
1037  Chlorine dioxide generated from sodium 
chlorite by electrolysis  PT    x x x x      x x       
1038  Chlorine dioxide generated from sodium 
chlorite by acidification  PT    x x x x      x x        
EN 4  EN Entry 
number  Substance name  Rapporteur 
Member 
State  EC number  CAS number  1 2 3 4 5 6 7 8 9 10 11 12 13 17 18 19 21 22 
1039  Chlorine dioxide  generated from sodium 
chlorite  by oxidation  PT    x x x x      x x       
1040  Chlorine dioxide generated from sodium 
chlorate and hydrogen peroxide in the presence 
of a strong acid  PT    x   x      x x       
494 2,2-Dibromo -2-cyanoacetamide (DBNPA)  DK 233-539-7 10222 -01-2  x  x  x     x x       
1022  Dialuminium chloride pentahydroxide  NL 234-933-1 12042 -91-0  x                 
1075  Reaction products of aluminium trihydroxide 
and hydrochloric acid and aluminium and water  NL    x                 
515 Bromide activated chloramine (BAC) generated 
from precursors ammonium bromide and 
sodium hypochlorite  SE             x x       
522 Pyrithione zinc  SE 236-671-3 13463 -41-7  x    x x  x x       x  
524 Dodecylguanidine monohydrochloride  ES 237-030-0 13590 -97-1      x     x        
529 Active bromine generated from bromine 
chloride  NL             x        
531 (Benzyloxy)methanol  AT 238-588-8 14548 -60-8      x       x      
550 D-Gluconic acid, compound with N,N'' -bis(4 -
chlorophenyl) -3,12-diimino -2,4,11,13 -
tetraazatetradecanediamidine (2:1) (CHDG)  PT 242-354-0 18472 -51-0 x x x                
554 p-[(Diiodomethyl)sulphonyl]toluene  CH 243-468-3 20018 -09-1      x x  x x         
559 (Benzothiazol -2-ylthio)methyl thiocyanate 
(TCMTB)  NO 244-445-0 21564 -17-0         x   x       
562 2-Methyl -4-oxo-3-(prop -2-ynyl)cyclopent -2-en-
1-yl 2,2 -dimethyl -3-(2-methylprop -1-
enyl)cyclopropanecarboxylate (Prallethrin)  EL 245-387-9 23031 -36-9               x    
566 Reaction products of paraformaldehyde and 2 -
hydroxypropylamine (ratio 1:1 ) (HPT)  AT    x    x     x  x      
571 2-Octyl -2H-isothiazol -3-one (OIT)  FR 247-761-7 26530 -20-1      x x  x x x  x      
577 Dimethyloctadecyl[3 -
(trimethoxysilyl)propyl]ammonium chloride  ES 248-595-8 27668 -52-6  x     x  x          
588 Bromochloro -5,5-dimethylimidazolidine -2,4-
dione (BCDMH)  NL 251-171-5 32718 -18-6  x         x x       
590 3-(4-Isopropylphenyl) -1,1-dimethylurea 
(Isoproturon ) DE 251-835-4 34123 -59-6       x   x         
599 S-[(6-Chloro -2-oxooxazolo[4,5 -b]pyridin -
3(2H) -yl)methyl] O,O -dimethyl thiophosphate 
(Azamethiphos)  IT 252-626-0 35575 -96-3               x     
EN 5  EN Entry 
number  Substance name  Rapporteur 
Member 
State  EC number  CAS number  1 2 3 4 5 6 7 8 9 10 11 12 13 17 18 19 21 22 
608 Dimethyltetradecyl[3 -
(trimethoxysilyl)propyl]ammonium chloride  PL 255-451-8 41591 -87-1         x          
1045  Eucalyptus citriodora oil, hydrated, cyclized  CZ  1245629 -80-
4                x   
1046  Cymbopogon winterianus oil, fractionated, 
hydrated, cyclized  CZ Not 
available  Not 
available                 x   
619 3-Iodo-2-propynylbutylcarbamate (IPBC)  DK 259-627-5 55406 -53-6       x  x x         
620 Tetrakis(hydroxymethyl)phosphonium 
sulphate(2:1) (THPS)  MT 259-709-0 55566 -30-8      x     x x       
648 4,5-Dichloro -2-octylisothiazol -3(2H) -one (4,5 -
Dichloro - 2-octyl -2H- isothiazol -3-one 
(DCOIT))  NO 264-843-8 64359 -81-5       x  x x x        
656 Reaction products of paraformaldehyde and 2 - 
hydroxypropylamine (ratio 3:2)  (MBO)  AT    x    x     x x x      
667 Alkyl (C 12-18) dimethylbenzyl ammonium 
chloride (ADBAC (C 12-18)) IT 269-919-4 68391 -01-5 x x x x      x x x      x 
671 Alkyl (C 12-16) dimethylbenzyl ammonium 
chloride (ADBAC/BKC (C 12-C16)) IT 270-325-2 68424 -85-1 x x        x x x      x 
673 Didecyldimethylammonium chloride (DDAC 
(C8-10)) IT 270-331-5 68424 -95-3 x x x x  x    x x x       
690 Quaternary ammonium compounds, benzyl -C12-
18-alkyldimethyl, salts with 1,2 -benzisothiazol -
3(2H) -one 1,1 -dioxide (1:1) (ADBAS)  MT 273-545-7 68989 -01-5  x  x               
691 Sodium N -(hydroxymethyl)glycinate  AT 274-357-8 70161 -44-3      x             
693 
 Pentapotassium 
bis(peroxymonosulfate)bis(sulfate) (KPMS)  SI 
 274-778-7 
 70693 -62-8 
  x 
 x 
 x x 
              
939 Active chlorine  generated from sodium chloride 
by electrolysis  SK             x        
1049  Active chlorine generated from sodium chloride 
and pentapotassium 
bis(peroxymonosu lfate)bis(sul fate) SI    x x x x              
1050  Active chlorine generated from seawater 
(sodium chloride) by electrolysis  FR             x        
1051  Active chlorine generated from magnesium 
chloride hexahydrate and potassium chloride by 
electrolysis  FR    x                 
1054  Active chlorine generated from sodium N - 
chlorosulfamate  SI      x       x x       
701 Dihydrogen bis[monoperoxyphthalato(2 -)-
O1,OO1]magnesate(2 -) (MMPP)  PL 279-013-0 84665 -66-7  x                  
EN 6  EN Entry 
number  Substance name  Rapporteur 
Member 
State  EC number  CAS number  1 2 3 4 5 6 7 8 9 10 11 12 13 17 18 19 21 22 
1024  Margosa extract from cold -pressed oil of the 
kernels of Azadirachta Indica extracted with 
super -critical carbon dioxide  DE                 x    
724 Alkyl (C 12-C14) dimethylbenzylammonium 
chloride (ADBAC (C 12-C14)) IT 287-089-1 85409 -22-9 x x x x      x x x      x 
725 Alkyl (C 12-C14) 
dimethyl( ethylbenzyl )ammonium chloride 
(ADEBAC (C 12-C14)) IT 287-090-7 85409 -23-0 x x x x      x x x      x 
1057  Chrysanthemum cinerariaefolium extract from 
open and mature flowers of  Tanacetum 
cinerariifolium obtained with hydrocarbon 
solvent  ES                 x x   
1058  Chrysanthemum cinerariaefolium extract from 
open and mature flowers of Tanacetum 
cinerariifolium obtained with supercritical 
carbon dioxide  ES                 x x   
744 Lavender, Lavandula hybrida , ext. / Lavandin 
oil PT 294-470-6 91722 -69-9                x   
779 Reaction products of: glutamic acid and N -(C12-
C14-alkyl)propylenediamine (Glucoprotamin)  DE 403-950-8 164907 -72-6  x  x               
785 6-(Phthalimido)peroxyhexanoic acid (PAP)  IT 410-850-8 128275 -31-0 x x                 
791 2-Butyl-benzo[d]isothiazol -3-one (BBIT)  CZ 420-590-7 4299 -07-4      x x  x x   x      
792 Chlorine dioxide generated from 
tetrachlorodecaoxide complex (TCDO) by 
acidification  DE    x  x               
811 Silver sodium hydrogen zirconium phosphate  SE 422-570-3 265647 -11-8    x     x          
797 cis-1-(3-Chloroallyl) -3,5,7 -triaza -1-
azoniaadamantane chloride (cis CTAC)  PL 426-020-3 51229 -78-8      x       x      
1014  Silver zeolite  SE Not 
available  Not 
available     x     x          
152 Reaction products of 5,5 -dimethylhydantoin, 5 -
ethyl -5-methylhydantoin with bromine and 
chlorine (DCDMH)  NL Not 
available  Not 
available            x        
459 Reaction mass of titanium dioxide and silver 
chloride  SE Not 
available  Not 
available  x x    x x  x x x        
777 Reaction products of 5,5 -dimethylhydantoin, 5 -
ethyl -5-methylhydantoin with chlorine 
(DCEMH)  NL Not 
available  Not 
available            x        
810 Silver phosphate glass  SE Not 
available  308069 -39-8  x     x  x          
1077  Silver borophosphate glass  SE    x     x  x           
EN 7  EN Entry 
number  Substance name  Rapporteur 
Member 
State  EC number  CAS number  1 2 3 4 5 6 7 8 9 10 11 12 13 17 18 19 21 22 
1078  Silver phosphoborate glass  SE    x     x  x          
824 Silver zinc zeolite  SE Not 
available  130328 -20-0  x  x   x  x          
1013  Silver copper zeolite  SE Not 
available  130328 -19-7    x     x          
1017  Silver adsorbed on silicon dioxide  (as a 
nanomaterial in the form of a stable aggregate 
with primary particles in the nanoscale)  SE Not 
available  Not 
available          x          
854 (RS) -3-Allyl -2-methyl -4-oxocyclopent -2-enyl-
(1R,3R;1R,3S) -2,2-dimethyl -3-(2-methylprop -
1-enyl) -cyclopropanecarboxylate (mixture of 4 
isomers 1R trans, 1R : 1R trans, 1S : 1R cis, 1R 
: 1R cis, 1S 4:4:1:1) (d -Allethrin)  DE Plant 
protection 
product  231937 -89-6               x    
843 4-Bromo -2-(4-chlorophenyl) -1-ethoxymethyl -5-
trifluoromethylpyrrole -3-carbonitrile 
(Chlorfenapyr)  PT Plant 
protection 
product  122453 -73-0               x    
859 Polymer of N -Methylmethanamine (EINECS 
204-697-4 with (chloromethyl)oxirane 
(EINECS 203 -439-8) / Polymeric quaternary 
ammonium chloride (PQ Polymer)  HU Polymer  25988 -97-0  x         x        
869 Poly(oxy -1,2-ethanediyl), .alpha. -[2-
(didecylmethylammonio)ethyl] - .omega. -
hydroxy -, propanoate (salt) (Bardap 26)  IT Polymer  94667 -33-1  x  x      x         
872 N-Didecyl -N-dipolyethoxyammonium borate / 
Didecylpolyoxethylammonium borate 
(Polymeric betaine)  EL Polymer  214710 -34-6        x           
1070  Orange, sweet, ext.  
Extractives and their physically modified 
derivatives such as tinctures, concretes, 
absolutes, essential oils, oleoresins, terpenes, 
terpene -free fractions, distillates, residues, etc., 
obtained from Citrus sinensis, Rutaceae.  CH 232-433-8 8028 -48-6                x   
1071  Garlic, ext.  
Extractives and their physically modified 
derivatives such as tinctures, concretes, 
absolutes, essential oils, oleoresins, terpenes, 
terpene -free fractions, distillates, residues, etc., 
obtained from Allium s ativum, Liliaceae.  AT 232-371-1 8008 -99-9                x   
1072  Brandy  tbd Not 
available  Not 
available                 x   
1073  Peanut butter  BE Not 
available  Not 
available                 x   
1074  Copper , powder  FR 231-159-6 7440 -50-8                 x   
EN 8  EN