G/SPS/N/CAN/1548  
4 April 2024  
(24-2883) Page: 1/2 
Committee on Sanitary and Phytosanitary Measures  Original: English/French  
 
  NOTIFICATION  
1. Notifying Member:  CANADA  
If applicable, name of local government involved:   
2. Agency responsible:  Health Canada  
3. Products covered (provide tariff item number(s) as specified in national 
schedules deposited with the WTO; ICS numbers should be provided in addition, 
where applicable):  Glucose oxidase from Saccharomyces  cerevisiae  LALL-GO 
(ICS codes: 67.220.20; 67.060)  
4. Regions or countries likely to be affected, to the extent relevant or practicable : 
[X] All trading partners   
[ ] Specific regions or countries:   
5. Title of the notified document:  Notice of Modification to the List of Permitted Food 
Enzymes  to Enable the Use of Glucose Oxidase from Saccharomyces cerevisiae  LALL-GO in 
Bread, Flour, Whole Wheat Flour and Unstandardized Bakery Products . Language(s):  
English and French . Number of pages:   
6. Description of content:  Health Canada's Food Directorate completed a premarket safety 
assessment of a food additive submission seeking authorization for the use of glucose 
oxidase from  Saccharomyces  cerevisiae  LALL-GO as a food enzyme in bread, flour, whole 
wheat flour, and unstandardized bakery products.  
The results of the premarket assessment support the safe ty of glucose oxidase from 
S. cerevisiae  LALL-GO for its requested use. Consequently, Health Canada has extended 
the use of glucose oxidase from S. cerevisiae  LALL-GO as described in the information 
document referenced above by modifying the List of Permitted Food Enzymes , effective 
22 March 2024.  
The purpose of the information document is  to publicly announce the Department's 
decision in this regard and to provide the appropriate contact information for those wishing 
to submit an inquiry or new scientific information relevant to the safety of this food 
additive.  
7. Objective and rationale : [X]  food safety, [  ] animal health, [  ] plant protection, 
[ ] protect humans from animal/plant pest or disease, [  ] protect territory from 
other damage from pests.   
8. Is there a relevant international standard? If so, identify the standard:  
[ ] Codex A limentarius Commission (e.g.  title or serial number of Codex 
standard or related text) :  
[ ] World Organization for Animal Health (OIE) (e.g.  Terrestrial or Aquatic 
Animal Health Code, chapter number) :  
[ ] International Plant Protection Convention (e.g.  ISPM number) :  G/SPS/N/CAN/1548  
 
- 2 - 
 
  [X] None  
Does this proposed regulation conform to the relevant international standard?  
[ ] Yes   [  ] No 
If no, describe, whenever possible, how  and why it deviates from the 
international standard:   
9. Other relevant documents and language(s) in which these are available:  
Health  Canada's Food and Nutrition – 'Public Involvement and Partnerships' Website, 
posted 22 March 2024 (available in English  and French):  
https://www.canada.ca/en/health -canada/services/food -nutrition/public -involvement -
partnerships.html  (English)  
https://www.canada.ca/fr/sante -canada/services/aliments -nutrition/participation -public -
partenariats.html  (French)  
10. Proposed date of adoption (dd/mm/yy) : The proposed food additive modification(s) 
will be legally enabl ed once published in Health Canada's Lists of Permitted Food Additives 
(https://www.canada.ca/en/health -canada/services /food-nutrition/food -safety/food -
additives/lists -permitted.html ). 
Proposed date of publication (dd/mm/yy) :  
11. Proposed date of entry into force: [  ] Six months from date of publication , and/or  
(dd/mm/yy) : The food additive modification(s) noted in this document come into force 
the day they are made to the Lists of Permitted Food Additives  
(https://www.canada.ca/en/health -canada/services/food -nutrition/food -safety/food -
additives/lists -permitted.html ). 
[ ] Trade facilitating measure   
12. Final date for comments: [  ] Sixty days from the date of circulation of the 
notification and/or (dd/mm/yy) : 5 June 2024  
Agency or authority designated to handle comments: [  ] National Notification 
Authority, [X]  National Enquiry Point. Address, fax number and e -mail address (if 
availa ble) of other body:   
13. Text(s) available from: [  ] National Notification Authority, [X]  National Enquiry 
Point. Address, fax number and e -mail address (if available) of other body:   
The Notice of Modification to the List of Permitted Food Enzymes  to Authorize the Use of 
Glucose Oxidase from Saccharomyces  cerevisiae  LALL-GO in Bread, Flour, Whole Wheat 
Flour and Unstandardized Bakery Products is available through the following weblink:  
https://www.canada.ca/en/health -canada/services/food -nutrition/public -involvement -
partnerships/notice -modification -list-permitted -enzymes -enable -glucose -oxidase -
saccharomyces -cerevisiae -lall-go-bread -flour-whole -wheat -unstandardized -bakery -
products.html  (English)  
https://www.canada.ca/fr/sante -canada/services/aliments -nutrition/participation -public -
partenariats/avis -modificat ion-liste-enzymes -autorisees -utilisation -glucose -oxydase -
saccharomyces -cerevisiae -lall-go-farine -entier -pain-produits -boulangerie -normalises.html  
(French)  
Canada's Notification Authority and Enquiry Point  
Technical Barri ers and Regulations Division  
Global Affairs Canada  
111 Sussex Drive  
Ottawa, Ontario, K1A 0G2  
Canada  
Tel: +(343) 203 4273  
Fax: +(613) 943 0346  
E-mail: enquirypoint@international.gc.ca