DRAFT  
 
 
Notification of the Ministry of Public Health  
(No....) B.E …. (….) 
Issued by virtue of the Food Act B.E. 2522  
Re: Extraction solvent used in food  production  
------------------------  
Whereas it is expedient to prescribe the measures to regulate e xtraction solvent 
used in food production  with a view of consumer protection ; 
By virtue of the provisions of section 5 paragraph one and section 6 (1), (2), (4),  
(5), (6), (7), (9) and (10) of the Food Act, B.E. 2522 (1979), the Minister of Public Health he reby  
issues the Notification as follows:  
Clause 1 The notification of the ministry of public health (No. 259), B.E. 2545 
issued under the food act, B.E. 2522 Re: Application of methyl alcohol as processing aid in 
some foods shall be repeal.  
Clause 2 This notification shall not apply to  the products that  have been 
regulated by specific notification  as follows :  
(1) Drinking water used as Extraction solvents  
(2) Edible oils and fats  used as Extraction solvents   
(3) Extraction solvents use in Food additive production   
Clause 3 In this Notification:  
“Extraction solvent”  means a food additive which is intended to be used as a 
processing aid to extract  substances during  the processing of raw materials, of foodstuffs, or 
of components or ingredients of these products and which is removed .  
 “Processing aid” means any substance or material which is not used for 
consumption as a food ingredient but is used in the production  of processed food, 
preparation of raw materials or ingredients of food to fulfil a technological purpose during 
the processing, and which may result in the non -intentional but unavoidable presence of 
such substance or derivatives thereof as residues in th e final product  
Clause 4 Extraction solvent used in food production shall be a specifically 
controlled food.  
 
 
Clause 5 Extraction solvent used in food production shall be in compliance with 
the quality or standards  as mentioned in;    
 
 
 
(DRAFT)  -2/3- 
DRAFT  (1) the latest version of  the Combined Compendium of Food Additive 
Specifications, FAO JECFA Monographs;  
(2) the notification of Food and Drug Administration  in accordance with the 
Notification of the Ministry of Public Health on food additives.  
Clause 6 Extraction solvent  which is a  mixture of two or more active ingredients 
and/or other ingredients shall not be harmful to health,  shall meet the technological 
purpose  and shall conform to the following requirements;  
(1) Active ingredients of the e xtraction solvent  shall be in compliance wi th the 
quality or standards  requirements as specified in Clause 5  
(2) Food additives used in extraction solvent shall comply with the condition of 
used under the notification of the ministry of public health on food additives  
(3) Water used in extraction solvent must conform to the quality or standards 
under the notification of the Ministry of Public Health on packed drinking water  
(4) Edible oils and fats  used in extraction solvent must conform to the quality or 
standards under the notification of the Ministry of Public Health on  Edible oils and fats  
(5) Arsenic in mixed substance of extraction solvent shall not exceed 3 milligrams 
per kilogram  
(6) Lead in mixed substance of  extraction solvent shall not exceed 10 milligrams 
per kilogram  
Clause 7 The use of extraction solvent  must conform to the Schedule annexed 
to this Notification  
In the case where the use of extraction solvent  is different from the 
use prescribed  in the Sch edule annexed to this Notification , the approval from the Food and 
Drug Administration must be obtained. In this regard, evidence and documents shall be 
submitted in accordance with the notification of the Ministry of Public Health on food 
additives.  
Claus e 8 The labelling of extraction solvent  used in food production shall 
comply with the Notification of the Ministry of Public Health regarding food additives.  
The labelling of food product which extraction solvent  used during production 
shall comply with t he Notification of the Ministry of Public Health on labelling of pre -
packaged food  
Clause 9 The use of container or packaging for extraction solvent  used in food 
production shall comply with the Notification of the Ministry of Public Health on food 
contain ers 
Clause 10 Produc ing or import ing of extraction solvent  for used in food 
production must comply with the Notification of the Ministry of Public Health on production 
practices, production equipment and utensils, and storage of food  
Clause 11 the producer  or the importer of extraction solvent  for used in food 
production who has the  license  prior to the date of this Notification comes into force shall -3/3- 
DRAFT  duly comply with this Notification within one years from the date this Notification comes into 
force  
Claus e 12 the producer or the importer of food product which use an extraction 
solvent  during production who has the  license prior to the date this Notification comes into 
force shall duly comply with this Notification within two years from the date this Notifi cation 
comes into force  
Clause 13 This Notification shall come into force as from the day following date 
of its publication in the Government Gazette onwards.  
Notified on………………………………….  
 
 
 
 
 
This English version of the notification is translated to meet the  need of the non -Thai speaking people.  
In case of any discrepancy between the Thai original and the English translation, the original Thai version 
shall prevail.   
DRAFT  Schedule Annexed to the Notification of The Ministry of Public Health (No. ….), B.E. …. (…..)  
Issued under the Food Act, B.E. 2522 (1979) Re: Extraction solvent used in food production  
No. List of substances  Types of food  Maximum use level  
(mg/kg)  Maximum residue level  
in food (mg/kg)  Specific condition  
1 Acetone  
(INS -; CAS 67 -64-1)  Edible fat or oils  
and food oils   GMP 0.1 Prohibit  use in the refining 
of olive -pomace oil  
Flavoring substance  
 GMP  30   
2 Butane or n-butane  
(INS 943a)  All foods  
 GMP  0.1   
Flavoring substance  GMP  1   
3 n-butanol or butan -1-
ol or butyl alcohol  
(INS -  ; CAS 76 -36-3) All foods  
 GMP  10   
4 Carbon dioxide  
(INS 290; CAS124-38-9)  
 All foods  
 GMP  GMP   
5 Cyclohexane) (INS -; 
CAS 110-82-7) Flavoring substance  
 GMP  1  
6 Dichloromethane  
(INS-; CAS 75-09-2) Decaffeinated coffee or tea  GMP  2  
Flavoring sub stance  GMP  0.02  
7 Diethyl ether  
(INS-; CAS 60 -29-7) Flavoring substance  
 GMP  2   -2/3- 
DRAFT  No. List of substances  Types of food  Maximum use level  
(mg/kg)  Maximum residue level  
in food (mg/kg)  Specific condition  
8 Ethanol  
(INS - ; CAS64-17-5) All foods  GMP GMP 
  Except for use in beverage  
do not exceed 5,000 mg/kg  
9 Ethyl acetate  
(INS -  ; CAS141-78-6) All foods  GMP GMP   
10 Ethyl methyl ketone  
(INS-; CAS 78-93-3)) Decaffeinated coffee or tea  
 GMP 2 The combined use with 
Hexane i s prohibited . 
Flavoring substance  GMP 2 
11 Hexanes  
(INS - ;  CAS -) Preparation of defatted 
protein products and 
defatted flours  GMP 10 The combined  use with 
Ethyl methyl ketone is 
prohibited . 
The defatted soya products 
as sold to the final consumer  GMP  30 
Preparation of defatted 
cereal germs  GMP  5 
Other foods  GMP  1 
12 Propan -2-ol or 
isopropyl alcohol  
(INS -  ;  CAS 67-63-0) All foods  GMP  10   
13 Propane or n-propane  
(INS 944)  All foods  GMP  1   -3/3- 
DRAFT  No. List of substances  Types of food  Maximum use level  
(mg/kg)  Maximum residue level  
in food (mg/kg)  Specific condition  
14 Toluene  
(INS-; CAS 108-88-3) Flavoring substance  GMP  1