G/SPS/N/CAN/1452  
 
22 August 2022  
(22-6334) Page: 1/2 
Committee on Sanitary and Phytosanitary Measures  Original: English/French  
 
  NOTIFICATION  
1. Notifying Member:  CANADA  
If applicable, name of local government involved:   
2. Agency responsible:  Health Canada  
3. Products covered (provide tariff item number(s) as specified in national 
schedules deposited with the WTO; ICS numbers should be provided in addition, 
where applicable):  Grape seed extract (oligomeric proanthocyanidins)  
4. Regions or countries likely to be affected, to the extent relevant or practicable : 
[X] All trading partners   
[ ] Specific regions or countries:   
5. Title of the notified document:  Health Canada's proposal to enable the use of grape 
seed extract (oligomeric proanthocyanidins) as a supplemental ingredient in foods . 
Language(s):  English and French . Number of pages:  4 
6. Description of content:  Health Canada's Food Directorate completed a detailed 
premarket safety assessment of grape seed extract for use as a supplemental ingredient in 
foods, under the Supplemented Foods regulatory framework. The results of the premarket 
assessment support the safety of standardized grape seed extracts based on the 
oligomeric proanthocyanidins content. Consequently, Health Canada intends to enable the 
use of grape seed extract (oligomeric proanthocyanidins) by modifying the List of 
Permitte d Supplemental Ingredients  as described in the Notice of Proposal information 
document.  
The purpose of this communication is to publicly announce the Department's intention in 
this regard and to provide the appropriate contact information for any inquiries  or for 
those wishing to submit new scientific information relevant to the safety of grape seed 
extract (oligomeric proanthocyanidins) when used as a supplemental ingredient in foods.  
7. Objective and rationale: [X]  food safety, [  ] animal health, [  ] plant protection, 
[ ] protect humans from animal/plant pest or disease, [  ] protect territory from 
other damage from pests.   
8. Is there a relevant international standard? If so, identify the standard:  
[ ] Codex Alimentarius Commission (e.g.  title or serial number of Codex 
standard or related text) :  
[ ] World Organization for Animal Health (OIE) (e.g.  Terrestrial or Aquatic 
Animal Health Code, chapter number) :  
[ ] International Plant Protection Convention (e.g.  ISPM number) :  
[X] None  
Does this proposed regulation conform to the relevant international standard?  G/SPS/N/CAN/1452  
 
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  [ ] Yes   [  ] No 
If no, describe, whenever possible, how and why it deviates from the 
international standard:   
9. Other relevant documents and language(s) in which these are available:  
Health Canada's Food and Nutrition – "Public Involvement and Partnerships" Website, 
posted 16 August 2022 (available in English and French):  
https://www.canada.ca/en/health -canada/services/food -nutrition/public -involvement -
partnerships.html  
https://www.canada.ca/fr/sante -canada/services/aliments -nutrition/participation -public -
partenariats.html  
10. Proposed date of adoption (dd/mm/yy) : The proposed supplemental ingredient will be 
legally enabled once published in Health Canada's List of permitted supplemental 
ingredients  (https://www.canada.ca/en/health -canada/services/food -
nutrition/supplemented -foods/technical -documents/list -permitted -food-ingredients.html ). 
Proposed date of publication (dd/mm/yy) :  
11. Proposed date of e ntry into force: [  ] Six months from date of publication , and/or  
(dd/mm/yy) : The supplemental ingredient modification noted in this document come 
into force the day they are made to the List of permitted supplemental ingredients  
(https://www.canada.ca/en/health -canada/services/food -nutrition/supplemented -
foods/technical -documents/list -permitte d-food-ingredients.html ). 
[ ] Trade facilitating measure   
12. Final date for comments: [  ] Sixty days from the date of circulation of the 
notification and/or (dd/mm/yy) : 29 October 2022  
Agency or authority designated to handle comments: [  ] National Notification 
Authority, [X]  National Enquiry Point. Address, fax number and e -mail address (if 
available) of other body:   
13. Text(s) available from: [  ] National Notification Authority, [X]  National Enquiry 
Point. Address, fax number and e -mail address (if available) of other body:   
The "Health Canada's proposal to enable the use of grape seed extract (oligomeric 
proanthocyanidins) as a supplemental ingredient in foods" is available through the 
following weblink:  
https://www.canada.ca/en/health -canada/services/food -nutrition/public -involvement -
partnerships/notice -proposal -enable -use-grape -seed-extract -supplemental -ingredient -
foods/document.html  (English)  
https://www.canada.ca/fr/sante -canada/services/aliments -nutrition/participation -public -
partenariats/avis -proposition -permettre -utilisation -extrait -pepins -raisin -ingredient -
supplementaire -aliments/document.html  (French)  
 
Canada's Notification Authority and Enquiry Point  
Technical Barriers and Regulations Division  
Global Affairs Canada  
111 Sussex Drive  
Ottawa, Ontario K1A 0G2  
Canada  
Tel: +(343) 203 4273 
Fax: +(613) 943 0346  
E-mail: enquirypoint@international.gc.ca