G/SPS/N/CAN/1535  
17 October 2023  
(23-6986) Page: 1/2 
Committee on Sanitary and Phytosanitary Measures  Original: English/French  
 
  NOTIFICATION  
1. Notifying Member:  CANADA  
If applicable, name of local government involved:   
2. Agency responsible:  Health Canada  
3. Products covered (provide tariff item number(s) as specified in national 
schedules deposited with the WTO; ICS numbers should be provided in addition, 
where applicable):  Cellulase from Trichoderma reesei RF11412 in Brewers' mash and 
Distillers' mash (ICS Codes: 67.220.20)  
4. Regions or countries likely to be affected, to the extent relevant or practicable : 
[X] All trading partners   
[ ] Specific regions or countries:   
5. Title of the notified document:  Notice of Modification to the List of Permitted Food 
Enzymes to Enable the Use of Cellulase from Trichoderma reesei  RF11412 in Brewers' 
mash and Distillers' mash . Language(s):  English and French . Number of pages:  3 and 4  
https://members.wto.org/crnattachments/2023/SPS/CAN/23_13030_00_e.pdf  
https://members.wto.org/crnattachments/2023/SPS/CAN/23_13030_00_f.pdf  
6. Description of content:  Health Canada's Food Directorate completed a premarket safety 
assessment of a food additiv e submission seeking authorization for the use of cellulase 
from Trichoderma reesei  RF11412 in brewers' mash and distillers' mash. The requested 
maximum level of use for this food enzyme is "Good Manufacturing Practice".  
The results of the premarket assess ment support the safety of cellulase from T. reesei  
RF11412 for its requested uses. Consequently, Health Canada has enabled the use of 
cellulase from this source as described in the information document by modifying the List 
of Permitted Food Enzymes , effective 11 October 2023.  
The purpose of this information document is to publicly announce the Department's decision 
in this regard and to provide the appropriate contact information for those wishing to submit 
an inquiry or new scientific information relevan t to the safety of this food additive.  
7. Objective and rationale: [X]  food safety, [  ] animal health, [  ] plant protection, 
[ ] protect humans from animal/plant pest or disease, [  ] protect territory from 
other damage from pests.   
8. Is there a relevant international standard? If so, identify the standard:  
[ ] Codex Alimentarius Commission (e.g.  title or serial number of Codex 
standard or related text) :  
[ ] World Organization for Animal Health (OIE) (e.g.  Terrestrial or Aquatic 
Animal Health Cod e, chapter number) :  
[ ] International Plant Protection Convention (e.g.  ISPM number) :  
[X] None  G/SPS/N/CAN/1535  
 
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  Does this proposed regulation conform to the relevant international standard?  
[ ] Yes   [  ] No 
If no, describe, whenever possible, how and why it deviates fro m the 
international standard:   
9. Other relevant documents and language(s) in which these are available:  Health 
Canada's Food and Nutrition – 'Public Involvement and Partnerships' Web site, posted 
11 October 2023  (available in English and French):  
https://www.canada.ca/en/health -canada/services/food -nutrition/public -involvement -
partnerships.html  (English ) 
https://www.canada.ca/fr/sante -canada/services/aliments -nutrition/participation -public -
partenariats.html  (French)   
10. Proposed date of adoption (dd/mm/yy) : 11 October 2023  
Proposed date of publication (dd/mm/yy) :  
11. Proposed date of entry into force: [  ] Six months from date of publication , and/or  
(dd/mm/yy) : 11 October 2023  
[ ] Trade facilitating measure   
12. Final date for comments: [  ] Sixty days from the date of circulation of the 
notification and/or (dd/mm/y y): 24 December 2023  
Agency or authority designated to handle comments: [  ] National Notification 
Authority, [X]  National Enquiry Point. Address, fax number and e -mail address (if 
available) of other body:   
13. Text(s) available from: [  ] National Notification Authority, [X]  National Enquiry 
Point. Address, fax number and e -mail address (if available) of other body:   
The "Notice of Modification to the List of Permitted Food Enzymes to Enable the Use of 
Cellulase from Trichoderma reesei RF11412 in Brewers' mash and Distillers' mash" is 
available through the following weblink:  
https://www.canada.ca/en/health -canada/services/food -nutrition/public -involvement -
partnerships/notice -modification -list-permitted -food-enzymes -enable -use-cellulase -
trichoderma -reesei -rf11412-brewers -distillers -mash.html  (English)  
https://www.canada.ca/fr/sante -canada/services/aliments -nutrition/participation -public -
partenariats/avis -modification -liste-enzymes -alimentaires -autorisees -permettre -utilisation -
cellulase -issue-trichoderma -reesei -rff1412 -biere-mout-distillerie.html  (French)  
Canada's Notification Authority and Enquiry Point  
Technical Barriers and Regulations Division  
Global Affairs Canada  
111 Sussex Drive  
Ottawa, Ontario K1A 0G2  
Canada  
Tel: +(343) 203 4273  
Fax: +(613) 943 0346  
Email: enquirypoint@international.gc.ca