Proposals to Amend the New 
Zealand ( Maximum Residue 
Levels for Agricultural 
Compounds) Food Notice   
 
New Zealand Food Safety Discussion  Paper  No: 2020/ 0 
 
 
 
Prepared for public consultation 
By New Zealand Food Safety  
 
 
ISBN No: 978-1-99-002571- 6 (online)  
ISSN No: 2624- 0157 (online)  
 
 
 
 July 2020 
 
 
Disclaimer  
 While every effort has been made to ensure the information in this publication is accurate, the  
Ministry for Primary Industries  does not accept any responsibility or liability for error of fact, omission, 
interpretation or opinion that may be present, nor  for the consequences of any decisions based on this 
information.  
 
This publication is available on the Ministry for Primary Industries  website at  
http://www.mpi.govt.nz/news -and-resources/publications/
  
  
© Crown Copyright -  Ministry for Primary Industries   
i Contents  Page 
 
1 Submissions  1 
2 Introduction  2 
2.1 Background  2 
2.2 Summary of Proposed Amendments  4 
3 Proposals  7 
3.1 Proposal to set MRLs for amisulbrom  7 
3.2 Proposal to amend the MRLs for azoxystrobin  8 
3.3 Proposal to amend the MRLs for cyantraniliprole  10 
3.4 Proposal to amend the MRLs for diflufenican  12 
3.5 Proposal to amend the MRLs for fluxapyroxad  13 
3.6 Proposal to amend the MRLs for folpet  15 
3.7 Proposal to set MRLs for mefentrifluconazole  16 
3.8 Proposal to set MRLs for prosulfocarb  18 
3.9 Proposal to amend MRLs for metolachlor  19 
3.10  Proposal to amend the MRLs for tebuconazole  21 
3.11  Proposal to exempt 1- triacontanol from compliance with a MRL  23 
3.12  Proposal to exempt eugenol from compliance with a MRL  23 
3.13  Proposal to exempt geraniol from compliance with a MRL  23 
3.14  Proposal to amend the exemption for hydrogen peroxide  23 
3.15  Proposal to exempt thymol from compliance with a MRL 24 
3.16  Proposal to remove the exemption for didecyl dimethyl ammonium chloride  24 
3.17  Proposal to amend the exemption for vaccine and diagnostic antigens  24 
   
New Zealand Food Safety  Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice •  1 1 Submissions  
New Zealand Food Safety  invites public comment on this discussion document, which 
outlines proposals to amend the New Zealand (Maximum Residue Levels for Agricultural 
Compounds) Food Notice.  
 
 
For each compound  you are commenting on, please clearly answer the following questions . 
Any additional comment is welcome, along with supporting discussion, and data or examples 
to illustrate particular points.  
 
On balance, do you oppose any of the commodity MRLs or exemptions proposed for 
this compound? 
 
Do you oppose a MRL  or exemption  being set at all  for this compound or for a 
commodity? 
 
If a MRL  or exemption  is to be set for this compound for the commodity, do you 
disagree with the level s or conditions  proposed? If so, why do you disagree?  
 
Submissions close at 5pm on 20 September  2020 . Your comments should be sent to:  
 
MRL Amendments  
New Zealand Food Safety  
Ministry for Primary Industries  
PO Box 2526 
Wellington 6140 
 
Email: MaximumResidueLevels@mpi.govt.nz . 
 Please include your name and address on your submission. If you are making comments on 
behalf of an organisation, also include your title and the name of the organisation.  
 Please make sure your comments can be clearly read, as a number of copies of your 
submission may be made.  
 
The Official Information Act  
The Official In formation Act 1982 (the OIA) states that information is to be made available 
unless there are grounds for withholding it. The grounds for withholding information are 
outlined in the OIA.  Submitters may wish to indicate any grounds for withholding informat ion 
contained in their submission.  Reasons for withholding information could include that information is commercially sensitive or that the submitters wish personal information such 
as names or contact details to be withheld.  MPI will take such indications into account when 
determining whether or not to release information.  Any decision to withhold information 
requested under the OIA may be reviewed by the Ombudsman.  
 
  
2 • Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice New Zealand Food Safety  2 Introduction  
Agricultural compounds are natural or synthetic substances used in the management of 
plants and animals, and include veterinary medicines, fertilisers, and pesticides ( e.g. 
fungicides, herbicides and insecticides). Growers and farmers use agricultural compounds to 
manage disease in animals and crops, protect the food supply, and maximise the quantity 
and quality of the food they grow.  
Use of these agricultural compounds can leave residues in the food from those crops and 
animals that must be managed. To ensure only the appropriate amount of agricultural 
compounds are used to achieve their intended purpose, a set of principles and methods 
known as good agricultural practice (GAP) are utilised. GAP covers the production of safe 
and good quality horticultural and animal products.  
GAP is established for each agricultural compound by evaluating public health, crop safety, animal health and safety, and occupational and environmental safety considerations for the 
range of treatments and use patterns. This involves determining the administration and 
application rates and ranges necessary for an agricultural compound to achieve its intended 
effects, while leaving the smallest amount of residue practicable without compromising that 
efficacy.  
Once the GAP has been established for a use for an agricultural compound, the residues 
resulting fro m its use up to the highest authorised dose or application rate is then used to 
establish maximum residue levels (MRLs) in food commodities from crops and animals 
associated with that use. The MRLs are then compared against the health based guidance 
value in an evaluation commonly referred to as the dietary exposure (or dietary risk) 
assessment. This is explained in more detail below.  
MRLs are the maximum legal levels for residues of agricultural compounds permitted in food 
for sale in New Zealand. They are established based on domestic uses of a particular 
compound, and are used to monitor GAP compliance in New Zealand while ensuring food 
safety.  Because they are based on New Zealand authorised uses according to domestic 
GAP, MRLs  may differ from those established overseas for a similar use because their GAP 
may be different.  However, as noted below, imported food can also comply with Codex 
MRLs.  
To meet New Zealand’s obligations under the Agreement on the Application of Sanitary and 
Phytosanitary Measur es (the SPS Agreement)  the proposed MRL will be notified to the 
World Trade Organization. Any country may choose to comment if they believe the proposed MRL represents a barrier to their trade.  
2.1 BACKGROUND  
MRLs are set out in the New Zealand (Maximum Residue Levels for Agricultural 
Compounds) Food Notice. This Notice is amended regularly  each year to reflect changes in 
the use of agricultural compounds in the production of food. The MRL Food Notice is 
available from the Ministry for Primary Industries (MPI) New Zealand Food Safety website 
at: https://www.mpi.govt.nz/dmsdocument/19550- maximum -residue- levels -for-agricultural -
compounds .  
New Zealand Food Safety administers the MRL Food Notice, with the final decision on any 
changes to the Notice resting with the Director -General of MPI. The Food Notice is issued 
under section 405 of the Food Act 2014. When setting or amending MRLs, the Director -
General must take into account:  
• the need to protect public health;  
• the desirability of avoiding unnecessary restrictions  on trade;   
New Zealand Food Safety  Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice •  3 • the desirability of maintaining consistency between New Zealand’s food standards 
and those  standards that apply internationally;  
• New Zealand’s obligations under any relevant international treaty, agreement, 
convention, or protocol, and, in parti cular, under the Australia- New Zealand Joint 
Food Standards Agreement; and  
• such other matters as appropriate.  
 
The requirements for the content of the MRL Food Notice are set out in Part 6 of the Food 
Regulations 2015, allowing for the promulgation of MRLs  for agricultural compounds as well 
as the promulgation of exemptions from compliance with MRLs. In addition to establishing the requirements on domestically produced foods, Part 6 of the Food Regulations also 
outlines the residue level compliance requirem ents for imported foods. Clause 144 states 
that food must contain residues of agricultural compounds:  
- no greater than the MRLs specified for that food in a notice set under the Food 
Act 2014 (section (1)(a)); or  
- the default MRL of 0.1 mg/kg (section (1)(c) ); or  
- for imported food, the current editions of either the Maximum Residue Limits 
(MRLs) and Extraneous Maximum Residue Limits (EMRLs) for Pesticides (Codex 
Pesticides Residues in Food Online Database), or the Maximum Residue Limits 
for Veterinary Drugs in Food (Codex Veterinary Drug Residue in Food Online 
Database) (section (1)(d)).  
 As imported food commodities can comply with either a Codex MRL or a MRL established in 
the MRL Food Notice, New Zealand’s obligations under the SPS Agreement  are met.  
On th e whole, the Regulations allow for the management of residues in all foods consumed 
in New Zealand.  
2.1.1 National Estimated Dietary Intake  
The chronic dietary exposure to a substance is estimated by the NEDI calculation, 
encompassing all authorised uses of the agricultural compound, and using food consumption 
data based upon the 1997 National Nutritional Survey for adults and the 1995 National 
Nutrition Survey of Australia, for children. The NEDI calculation is made in accordance with 
Guidelines for predicting dietary intake of pesticide residues (revised) [World Health 
Organization, 1997]. The NEDI calculation provides an estimation of the potential chronic 
exposure to toxicologically relevant residues in all food derived from crops/livestock treated 
with the agricultural compound according to the authorised GAP use. 
The possible implications for consumer health are considered during the toxicological and 
dietary risk assessments, by comparing the NEDI with a Health Based Guidance Value 
(HBGV ). Provided the estimated dietary exposure of all toxicologically relevant residue 
components in all fresh and processed food is less than the HBGV, the use of an agricultural compound according to GAP is unlikely to pose a health risk to consumers.  
2.1.2 Health Based Guidance Values  
The HBGV used in determining the estimated dietary exposure may be either a Potential 
Daily Exposure (food) (PDE (food)) or an Acceptable Daily Intake (ADI). The ADI and PDE (food) 
are largely equivalent, as they are determined using the same set of t oxicology data and 
through a very similar scientific process. HBGVs are reported as milligrams of compound per 
kilogram bodyweight  per day  (mg/kg  bw/d ). 
A PDE (food) is a value determined by a toxicological evaluation by the New Zealand 
Environmental Protec tion Authority ( NZ EPA) as part of its responsibility for managing public 
health under the Hazardous Substances and New Organisms Act 1996 (the HSNO Act).  A  
4 • Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice New Zealand Food Safety  PDE (food) gives the potential daily exposure a person may be subject to from a substance, via 
food.  
An ADI is defined by the World Health Organization (WHO) as: “the daily intake which, during 
an entire lifetime, appears to be without appreciable risk on the basis of all the known facts at 
the time”. “Without appreciable risk” has been further defined  as: “the practical certainty that 
injury will not result even after a lifetime of exposure”. ADIs are established by the WHO and Food and Agriculture Organization (FAO) of the United Nations joint expert committees, 
which are made up of toxicologists and residue specialists. The ADI information from these 
joint committees also feeds into the Codex Alimentarius Commission (Codex), which sets 
international MRLs.  
As required by the HSNO Act in New Zealand, New Zealand Food Safety  uses the PDE
(food) 
set by th e NZ EPA as the HBGV for the estimation of dietary exposure when one is available. 
If there is no PDE (food), the estimated dietary exposure is compared with the ADI, set by the 
WHO/FAO joint expert committees, the Australian Pesticides and Veterinary Medic ines 
Authority (APVMA), the European Food Safety Authority (EFSA), or another regulatory 
authority. If none of these are available, the HBGV used will be a New Zealand Food Safety -
determined ADI.   
2.1.3 International MRLs and Trade  
Where MRLs are being set, t he “Relevant International MRLs” table listed in each entry is a 
summary of the MRLs set by Codex and a selection of other international regulatory bodies 
reviewed to evaluate trade risk. For animal commodities, the MRLs set by Australia, Canada, 
China, Co dex, the European Union, Japan, and the USA  are reviewed and compared; for 
horticultural commodities, MRLs set by Codex and Australia are reviewed and compared. Other international MRLs are reviewed and reported in the table if there is a particular trade 
risk to be considered for those regions. If a particular international body or regulator does not 
have MRLs set for the species or crop for which a New Zealand MRL is being proposed, that 
international body or regulator is omitted from the “other internati onal MRLs” section of the 
proposal entry.  
 
Where MRL exemptions are proposed, the proposed exemptions from compliance with a 
MRL have been thoroughly assessed in accordance with international methodologies published by the Organisation for Economic Cooperation and Development (OECD), 
International Cooperation on Harmonisation of Technical Requirements for Registration of 
Veterinary Medicinal Products (VICH), or FAO. Each proposal includes a discussion of the 
rationale behind the considerations for exemption, and a discussion of the assessed risks. 
New Zealand Food Safety has evaluated the potential food safety and dietary intake risks 
associated with promulgating an exemption, and determined that MRLs are not required to 
manage compliance to GAP or food safe ty risk.  
 
2.2 SUMMARY OF PROPOSED AMENDMENTS  
The proposed MRLs have been thoroughly assessed in accordance with international methodologies published by the Organisation for Economic Cooperation and Development 
(OECD) , International Cooperation on Harmonisation of Technical Requirements for 
Registration of Veterinary Medicinal Products (VICH) , or FAO. Information on the technical 
assessment of each proposal is included in this document (refer section 3) and covers:  
 
• rationale;  
• chemical information;  
• good agricultural practice;  
• residues information;  
• dietary risk assessment;  
• toxicological/public health assessment; and   
New Zealand Food Safety  Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice •  5 • MRLs set by Codex and other relevant authorities (e.g. Australia, Canada, China, EU, 
Japan, USA)  
 
Where an existing entry is proposed for  revision, new or revised MRLs are highlighted in bold 
print, and MRLs proposed for revocation are identified using a strikethrough.  
 
MPI has reviewed the estimated dietary exposure assessments associated with all 
authorised and proposed uses according to  what has been established as GAP for New 
Zealand, compared them with the appropriate HBGV (the PDE (food) or an ADI), and has 
concluded that residues arising from these uses are unlikely to present any public health or food safety concerns.  
2.2.1 Amendments to S chedule 1: New  and Amended MRLs  
MPI proposes to add new MRLs to the Food Notice, and/or amend the existing entries , for 
the following compounds:  
• Amisulbro m: 0.02 mg/kg in head brassicas, 0.02 mg/kg in flowerhead brassicas, and 
0.1 mg/kg in leafy vegetable brassicas . 
• Azoxystrobin: 0.01(*) mg/kg in eggs, 0.01(*) mg/kg in mammalian fat, 0.01(*) mg/kg in 
mammalian meat, 0.01(*) mg/kg in mammalian offal, 0.005 mg/kg in milk, 0.01(*) 
mg/kg in poultry fat, 0.01(*) mg/kg in poultry meat, and 0.01(*) mg/kg in poult ry offal.  
• Cyantraniliprole: 0.02 mg/kg in mammalian kidney, 0.03 mg/kg in mammalian liver, and 0.02 mg/kg in milk.  
• Diflufenican:  0.02(*) mg/kg in eggs, 0.02(*) mg/kg in mammalian fat, 0.02(*) mg/kg in 
mammalian meat, 0.02(*) mg/kg in mammalian offal, 0.01( *) mg/kg in milk, 0.01(*) 
mg/kg in peas (without pods), 0.02(*) mg/kg in poultry meat, and 0.02(*) mg/kg in poultry offal.  
• Fluxapyroxad:  0.01(*) mg/kg in eggs, 0.03 mg/kg in mammalian offal, 0.01(*) mg/kg in 
poultry fat, 0.01(*) mg/kg in poultry meat, and 0.01(*) mg/kg in poultry offal.  
• Folpet:  0.6 mg/kg in barley grain, 0.05(*) mg/kg in eggs, 0.05(*) mg/kg in mammalian 
meat, 0.05(*) mg/kg in mammalian offal, 0.05(*) mg/kg in milk, 0.05(*) mg/kg in poultry meat, and 0.05(*) mg/kg in poultry offal.  
• Mefentri fluconazole: 2.0 mg/kg in barley  grain , 0.01(*) mg/kg in eggs, 0.1 mg/kg in 
mammalian fat, 0.1 mg/kg in mammalian kidney, 0.3 mg/kg in mammalian liver, 0.02 mg/kg in mammalian meat, 0.02 mg/kg in milk, 0.02 mg/kg in poultry fat, 0.01(*) 
mg/kg in poultry meat, 0.02 mg/kg in poultry offal, and 0.5 mg/kg in wheat  grain . 
• Prosulfocarb: 0.01(*) mg/kg in potatoes.  
• Metolachlor: 0.01(*) mg/kg in potatoes . 
• Tebuconazole: 0.01(*) mg/kg in eggs, 0.01(*) mg/kg in mammalian fat, 0.01(*) mg/kg 
in mammalian kidney, 0.07 m g/kg in mammalian liver, 0.01(*) mg/kg in mammalian 
meat, 0.01(*) mg/kg in milk, 0.01(*) mg/kg in poultry fat, 0.01(*) mg/kg in poultry meat, and 0.01(*) mg/kg in poultry offal.  
 (*) indicates that the maximum residue level has been set at or about the li mit of analytical 
quantification.   
6 • Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice New Zealand Food Safety  2.2.2 Amendments to Schedule 2 : Exemptions from Maximum Residue Levels for Agricultural 
Chemicals 
• MPI proposes to add  the following new exemptions to the list of agricultural 
compounds in Schedule 2 of the Food Notice, for whic h no maximum residue levels 
apply:  
o 1-triacontanol, when used as a plant growth regulator on pasture;  
o Eugenol, when used as a fungicide on grapevines;  
o Geraniol, when used as a fungicide on grapevines; and  
o Thymol, when used as a fungicide on grapevines.  
• MPI proposes to amend the current entry for hydrogen peroxide in the list of 
agricultural compounds in Schedule 2 of the Food Notice, for which no maximum 
residue levels apply.  The entry will be amended to extend the exempted use o f the 
compound as a fungicide and bactericide to include both fruits and vegetables.   
• MPI proposes to remove the current entry fo r Didecyl Dimethyl Ammonium Chloride 
from the list of agricultural compounds in Schedule 2 of the Food Notice, for which no 
maximum residue levels  apply.  This compound is no longer approved for use as an 
agricultural compound under the Agricultural Compounds and Veterinary Medicines 
Act 1997.   
2.2.3 Amendment  to Schedule 3: Exemptions from Maximum Residue Levels for Veterinary 
Medicines  
• MPI proposes to  amend the current entry for Vaccine and Diagnostic Antigens in the 
list of agricultural compounds in Schedule 3 of the Food Notice, for which no maximum residue levels apply. The entry will be amended to allow for the exemption 
to include immunostimulants  derived from bacterial cell wall components.  
   
New Zealand Food Safety  Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice •  7 3 Proposals  
3.1 PROPOSAL TO S ET MRLS FOR  AMISULBROM  
It is proposed that MRLs are set for amisulbrom to support the GAP use of the compound on 
brassica  crops.  Amisulbrom  is a new agricultural compound in New Zealand.  
There is currently no entry for amisulbrom in the Notice. The new entry in Schedule 1 of the Notice will read:  
Compound 
Common Name  CAS#  Residue to which the maximum residue level  
applies  Food  Maximum  Residu e 
Level (mg/kg)  
Amisulbrom  348635- 87-0 Amisulbrom  Head brassicas  Flowerhead brassicas  
Leafy vegetable brassicas  0.02 0.02 
0.1 
3.1.1 Amendment Rationale  
The MRLs are being proposed to support the use of amisulbrom  on vegetable and leafy 
vegetable brassica seedlings in accordance with the use patterns proposed as GAP in New 
Zealand.  
3.1.2 Good Agricultural Practice  
Amisulbrom is a ‘quinone inside inhibitor’ fungicide used as a root drench on vegetable and 
leafy vegetable brassica seedlings  to control clubroot. The compound acts by inhibiting 
mitochondrial respiration in the target fungus, and is applied at a rate of 10  gai per 1000 
seedlings within 48 hours prior to  transplanting.  Amisulbrom must be applied before 
seedlings are planted out , and attract a withholding period to enforce this.      
3.1.3 Residue Information  
The residue data for the use of amisulbrom o n vegetable and leafy vegetable brassicas were 
sufficient to conclude that, when applied as per the proposed GAP use pattern and 
complying with the applicable withholding period, residues of parent amisulbrom should not 
exceed 0.02 mg/kg for head and flowerhead brassicas or  0.1 mg/kg for leafy vegetable 
brassicas.  
Trial data evaluating the metabolism of the compound demonstrated that parent amisulbrom 
was the main residue detected in plant -derived food commodities. It is therefore considered 
that ‘amisulbrom’ is sufficient to function as both the residue definition for GAP compliance 
and dietary intake assessments for plant -derived commodities.  
Animal commodity MRLs were not required  as vegetable and leafy vegetable brassicas are 
not considered a primary ani mal feed.  
3.1.4 Dietary Risk Assessment  
The HBGV of 0.084 mg/kg bw/d, and the stated dietary intake residue definition, were considered appropriate for use in the  dietary intake  assessment. Based on the residue profile 
expected in food from crops treated with am isulbrom, the NEDI is estimated to total less than 
0.02% of the HBGV.
  
MPI has therefore determined that the use of amisulbrom, when use according to the GAP 
specified above, is unlikely to pose any health risks from authorised use.  
3.1.5 Relevant International  MRLs  
Country                                                          Food  Maximum Residue  
Level (mg/kg)  
Australia  Brassica (cole or cabbage) vegetables, head cabbages,  and 
flowerhead brassicas  2  
8 • Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice New Zealand Food Safety  3.2 PROPOSAL TO  AMEND THE MRLS FOR  AZOXYSTROBIN  
It is proposed that the Notice entry for  azoxystrobin is amended to set  MRL s for animal 
commodities t o support the GAP use of the compound on fodder beets used as animal feed . 
The revised entry for azoxystrobin in Schedule 1 of the Notice will read as follows. C hanges 
are shown in bold:  
Compound 
Common Name  CAS#  Residue to which the maximum residue level 
applies  Food  Maximum Residue 
Level (mg/kg)  
Azoxystrobin  131860- 33-8 Plant commodities : 
Azoxystrobin and its z -isomer  
Animal commodities: 
Azoxystrobin  Cereal grains (except maize)  
Eggs  
Grapes  
Maize  
Mammalian fat  
Mammalian meat  
Mammalian offal  
Milk 
Onions  
Peas (without pods)  
Poultry fat  
Poultry meat  
Poultry offal  
Potatoes  
Sweetcorn 
Tomatoes  0.2 
0.01(*)  
1 
0.01(*)  
0.01(*)  
0.01(*)  
0.01(*)  
0.005 
0.01(*)  
0.02(*)  
0.01(*)  
0.01(*)  
0.01(*)  
0.02(*)  
0.01(*)  
0.01(*)  
 (*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.  
3.2.1 Amendment Rationale  
The MRL s are being proposed to support an expansion of the use of azoxystrobin to fodder  
beets for animal consumption,  in accordance with the use pattern proposed as GAP in New 
Zealand.  
3.2.2 Good Agricultural Practice  
Azoxystrobin is a methoxyacrilate strobiliuri n currently used to control fungal disease in peas, 
onions, potatoes, tomatoes, grapes, and cereal crops. The compound acts by inhibiting 
mitochondrial respiration and thereby inhibiting spore germination and mycelial growth. The 
new use has been proposed to manage rust, powdery mildew, and Cercospora infections in 
fodder beet crops grown solely for animal consumption. For th is additional use,  the 
compound is applied as a foliar spray  at a rate of 120 gai/ha (co-formulated with 200 gai/ha 
tebuconazole)  when disease first becomes active in the crop, and no sooner than 14 days 
later. A withholding period of 28 days applies to this use for both harvest and grazing of the 
crop.  
3.2.3 Residue Information  
The residue data for the use of azoxystrobin were  sufficient to conclude that, when applied 
according to the proposed GAP use pattern and the withholding period is observed, residues 
of azoxystrobin should not exceed 0.01 mg/kg in all animal commodities or 0.005 mg/kg in 
milk. Animal metabolism and feedi ng studies confirmed that parent azoxystrobin will be 
sufficient to manage both GAP compliance and dietary intake for animal commodities, in line 
with the residue definitions established by Codex.  
3.2.4 Dietary Risk Assessment  
The HBGV  of 0.1 mg/kg bw/d, and the stated dietary intake residue definition, were 
considered appropriate for use in the  dietary intake  assessment. Based on the residue profile 
expected in animal commodities after consumption of feed crops treated with azoxystrobin, 
the NEDI is estimated t o total less than 4 % of the HBGV.   
New Zealand Food Safety  Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice •  9 MPI has therefore determined that the use of azoxystrobin on animal feed crops , when use  
according to the GAP specified above, is unlikely to pose any health risks from authorised 
use.   
3.2.5 Relevant International MRLs  
Country                                                        Food  Maximum Residue  
Level (mg/kg)  
Australia  Edible offal (mammalian)  
Eggs  
Meat (mammalian) [in the fat]  
Milks  
Poultry meat  and edible offal  0.03 
0.01 
0.02 
0.005 
0.01 
Canada Meat of cattle, sheep, horses, and hogs  
Kidney of cattle, sheep, horses, and hogs  
Liver of cattle, sheep, horses and hogs  
Meat byproducts of cattle, sheep, horses, and hogs  
Milk  
Fat, meat, and liver  of poultry  
Eggs  0.01 
0.06 
0.3 
0.01 
0.006 
0.01 
0.01 
China  Meat from mammals (with the exception of marine mammal), 
expressed as residue in the fat  
Viscera of mammal animals (with the exception of marine mammal)  
Poultry meat and viscera  
Eggs  
Raw milk  
Milk fat   
0.05 
0.07 
0.01 
0.01 
0.01 
0.03 
Codex  Edible offal (mammalian)                         
Eggs  
Meat (from mammals other than marine mammals)  
Milk fats  
Milks  
Poultry meat  
Poultry, edible offal of  0.07 
0.01 0.05 
0.03 
0.01 
0.01 
0.01 
EU Swine, bovine, sheep, goat and equine muscle  
Swine, bovine, sheep, goat and equine fat  
Swine, bovine, sheep, goat and equine liver  
Swine, bovine, sheep, goat and equine kidney  
Swine, bovine, sheep, goat and equine edible offals (other than 
liver and kidney)  
Milk 
Poultry muscle, fat, liver, kidney, and edible offals (other than liver 
and kidney)  
Eggs  0.01 
0.05 
0.07 
0.07 
 
0.07 
0.01 
 
0.01 
0.01 
Japan Cattle, pig, and other terrestrial mammal muscle  
Cattle, pig, and other terrestrial mammal fat  
Cattle, pig, and other terrestrial mammal liver  
Cattle, pig, and other terrestrial mammal kidney  
Cattle, pig, and other terrestrial mammal edible offal  
Milk 
All chicken and other poultry commodities, including eggs  0.05 
0.05 0.07 
0.07 
0.07 
0.01 
0.01 
United States  Cattle, goat , horse, and sheep  by products  
Cattle, goat , horse, and sheep kidney  
Cattle,  goat, horse, and sheep liver 
Cattle, goat , horse, and sheep meat  
Goat , horse, and sheep fat 
Hog by products , fat, kidney, liver and meat  
Milk 0.07 
0.07 
0.07 
0.01 
0.03 
0.01 
0.006   
10 • Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice New Zealand Food Safety  3.3 PROPOSAL TO  AMEND THE MRLS FOR  CYANTRANILIPROLE  
It is proposed that the Notice entry for cyantraniliprole is  amended to set MRLs to support the 
GAP use of the compound on fodder beets . 
The revised entry for  cyantraniliprole in Schedule 1 of the Notice will read as follows. 
Changes are shown in bold:  
Compound 
Common Name  CAS#  Residue to which the maximum residue level  
applies  Food  Maximum Residue 
Level (mg/kg)  
Cyantraniliprole  736994- 63-1 Cyantraniliprole  Bulb onions  
Mammalian fat  
Mammalian kidney  
Mammalian liver  
Mammalian meat  
Milk  
Potatoes  
Tomatoes   0.01(*)  
0.01(*)  
0.02 
0.03 
0.01(*)  
0.02 
0.01(*)  
0.1 
(*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.  
3.3.1 Amendment Rationale  
The MRL s are being proposed to support the use of  cyantraniliprole as an insecticide for 
control of European leaf miner on fodder beets  in accordance with the use pattern proposed 
as GAP in New Zealand, and to take into account new information on residues in rotational 
crops used for animal feed.  
3.3.2 Good Agricultural Practice 
Cyantraniliprole belongs to the diamide class of insecticides, selectively activating and 
binding to the ryanodine receptors  in insect muscle cells . Cyantraniliprole is an established 
insecticide with the same use pattern and withholding period in fodder brassicas for control of European leaf miner and other pests. There are also approved uses in field tomatoes , 
potatoes and onions.   
The proposed use  in fodder beets is for application of 15 gai/ha cyantraniliprole when pest 
monitoring indicates that trigger levels of pest insects have been reached, with a maximum of 
three applications per season,  and a withholding period of 28 days after last application for 
grazing or treated crop being fed to livestock .  
3.3.3 Residue Information  
The residue data for the use of cyantraniliprole were sufficient to conclude that, when applied as per the proposed GAP use pattern and complying with the applicable withholding period,  
residues of cyantraniliprole should not exceed 0.02 mg/kg in mammalian kidney, 0.03 mg/kg 
in mammalian liver, and 0.02 mg/kg in milk. These revised MRLs are based on all potential 
sources of cyantraniliprole in animal feed, including the data provided to support the new use 
in fodder beets , and new information that cereal  crops  grown as rotational crops  after 
cyantraniliprole use and used for animal feed will contribute to the animal dietary burden to a 
larger extent than previously reported . The revised MRLs are therefore a more accurate 
representation of New Zealand GAP and the residue profile expected in animal commodities.  
The current residue definitions remain unchanged. These are  ‘cyantraniliprole’ for GAP 
compliance in plant and animal commodities and dietary intake in plant commodities; and 
‘Sum of cyantraniliprole, 2- [3-Bromo -1-(3-chloro- 2-pyridinyl) -1H-pyrazol -5-yl]-3,4-dihydro- 3,8- 
dimethyl -4-oxo-6-quinazolinecarbonitrile [IN -J9Z38], 2- [3-Bromo -1-(3-chloro- 2-pyridinyl) - 1H-
pyrazol -5-yl]-1,4-dihydro- 8-methyl -4-oxo-6-quinazolinecarbonitrile [IN -MLA84], 3-  Bromo -1-
(3-chloro-2-pyridinyl) -N-[4-cyano- 2-(hydroxymethyl) -6- [(methylamino)carbonyl]phenyl] -1H-
pyrazole -5-carboxamide [IN - N7B69] and3- Bromo -1- (3-chloro- 2-pyridinyl) -N-[4-cyano- 
New Zealand Food Safety  Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice •  11 2[[(hydroxymethyl)amino]carbonyl] -6-methylphenyl] -1Hpyrazole- 5-carboxamide [IN -MYX98], 
expressed as cyantraniliprole’ for dietary intake assessments in  animal commodities . 
3.3.4 Dietary Risk Assessment  
The HBGV of 0.007 mg/kg bw/d,  and the stated dietary intake residue definitions , were 
considered appropriate for use in the  dietary intake  assessment. The total NEDI from  all 
horticultural and animal commodities is estimated to total less than 4% of the HBG V.  
MPI has therefore determined that the additional use of cyantraniliprole, when used 
according to the GAP specified above, is unlikely to pose any health risks from authorised 
use. 
3.3.5 Relevant International MRLs  
Country                                                        Food  Maximum Residue  
Level (mg/kg)  
Canada Meat byproducts of goats, sheep, horses, and cattle  
Fat of goats, sheep, horses  and cattle 
Meat of goats, sheep, horses , and cattle   
Meat and meat byproducts of hogs  
Milk 0.4 
0.1 
0.1 
0.01 
0.2 
Codex  Edible offal (mammalian)  
Mammalian fats (except milk fats)   
Meat (from mammals other than marine mammals)   
Milks                       1.5 
0.5 
0.2 
0.6 
EU Swine, bovine, sheep, goat, and equine muscle  
Swine, bovine, sheep, goat, and equine fat  
Swine, bovine, sheep, goat, and equine liver  
Swine, bovine, sheep, goat, and equine kidney  
Swine, bovine, sheep, goat, and equine edible offals  (other than 
liver and kidney)  
Milk 0.2 
0.5 
1.5 
1.5 
 
1.5 
0.02 
Japan Cattle  and other terrestrial mammal muscle  
Cattle and other terrestrial mammal fat  
Cattle and other terrestrial mammal liver  
Cattle and other terrestrial mammal kidney  
Cattle and other terrestrial mammal edible offal  
Milk 0.2 
0.5 
2 
2 
2 
0.6 
United States  Cattle, goat, horse, and sheep by products  
Cattle, goat, horse, and sheep kidney  
Cattle, goat, horse, and sheep liver  
Cattle, goat, horse, and sheep meat  
Goat, horse, and sheep fat  
Milk 0.4 
0.4 
0.4 
0.1 
0.1 
0.2 
 
   
12 • Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice New Zealand Food Safety  3.4 PROPOSAL TO  AMEND THE MRLS FOR  DIFLUFENICAN   
It is proposed that the Notice entry for diflufenican is amended to set MRLs for animal 
commodities to support the GAP use of the compound on peas  for processing . 
The revised entry for diflufenican in Schedule 1 of the Notice will read as follows. Changes 
are shown in bold:  
Compound 
Common Name  CAS#  Residue to which the maximum residue level 
applies  Food  Maximum Residue 
Level (mg/kg)  
Diflufenican  83164- 33-4 Diflufenican  Barley  
Eggs  
Mammalian fat  
Mamm alian meat  
Mammalian offal  
Milk 
Peas (without pods)  
Poultry meat  
Poultry offal  
Wheat  0.01(*)  
0.02(*)  
0.02(*)  
0.02(*)  
0.02(*)  
0.01(*)  
0.01(*)  
0.02(*)  
0.02(*)  
0.01(*)  
(*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.  
3.4.1 Amendment Rationale  
The MRL is being proposed to support an expansion of the use of diflufenican to peas  for 
processing . The proposed MRLs will manage the use of the compound as a herbicide for the 
control of broad leaf weeds  in accordance with the use pattern proposed as GAP in New 
Zealand.  
3.4.2 Good Agricultural Practice  
Diflufenican  is an anilide herbicide which acts by inhibiting carotenoid biosynthesis  and 
thereby preventing photosynthesis in the target plant. The compound is currently used in the 
management of a broadleaf weeds in pasture grasses and cereal crops.  For the additional 
use in peas , the compound is applied at a rate of 100 gai/ha to control weeds post -
emergence up to the 4- leaf s tage.  This use is restricted to treatment before the fifth node 
growth stage (BBCH 35). As pea crops would not be grazed or harvested prior to this stage, 
an animal feed related withholding period is not required.  
3.4.3 Residue Information  
The residue data for the use of diflufenican on peas  are sufficient to conclude that, when 
applied according to the proposed GAP use pattern and observing the restriction, residues of 
diflufenican  should not exceed the limit of detection of 0.01 mg/kg. The  current residue 
definition of ‘ diflufenican’  remains appropriate for plant commodities (for both GAP 
compliance and dietary intake assessment).  
Because peas including their vines  is used as an animal feed, the potential for residue 
transfer for animal co mmodities was evaluated. Animal metabolism study data in ruminants 
and poultry found that diflufenican  is mainly excreted with a small amount of residues 
remaining in tissues; that retained residue is largely parent diflufenican. The GAP compliance 
and dietary intake definitions for animal commodities can therefore align with plant 
commodities as parent diflufenican.   
The metabolism study data also confirmed that, at the estimated New Zealand animal dietary 
burden for both pea crops and cereal crops , residu es in  both ruminant  and poultry 
commodities can be expected to remain below the limits of quantification. For animal commodities, these are 0.01 mg/kg in milk and 0.02 mg/kg in all tissue commodities and 
eggs. This approach is in line with that used in the  EU for animal commodity MRLs.    
New Zealand Food Safety  Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice •  13 3.4.4 Dietary Risk Assessment  
The HBGV  of 0.1 mg/kg bw/d,  and the stated dietary intake residue definition, were 
considered appropriate for use in the dietary intake assessment.  Based on the residue profile 
expected in food from all horticultural and animal commodities, the NEDI is estimated to total 
less than 0.3 % of the HBGV.  
MPI has therefore determined that the use of diflufenican on peas  without pods , when use 
according to the GAP specified above, is unlikely to pose any health risks from authorised 
use.   
3.4.5 Relevant International MRLs  
Country                                                        Food  Maximum Residue  
Level (mg/kg)  
Australia  Edible offal (mammalian)  
Eggs  
Meat (mammalian) [in the fat]  
Milks  
Peas  
Poultry meat  
Poultry, edible offal of  0.1 
0.02 
0.05 
0.01 
0.05 
0.02 
0.02 
EU All animal commodities except milk  
Milk 0.02 
0.01 
3.5 PROPOSAL TO  AMEND THE MRLS FOR  FLUXAPYROXAD  
It is proposed that the Notice entry for fluxapyroxad is amended to set MRLs to better 
support the GAP use of the compound on wheat and barley . 
The revised entry for fludioxonil in Schedule 1 of the Notice will read as follows. Changes are 
shown in bold:  
Compound 
Common Name  CAS#  Residue to which the 
maximum residue level 
applies  Food  Maximum Residue 
Level (mg/kg)  
Fluxapyroxad 907204- 31-3 Fluxapyroxad Apples  
Barley grain Bulb vegetables  
Eggs  
Mammalian offal  
Mammalian fat  
Mammalian meat  
Milk 
Pears  
Poultry fat  
Poultry meat  
Poultry offal  
Stone fruits  
Wheat grain 
Winter squash  0.02 0.3 
0.2 
0.01(*)  
0.03 
0.05 
0.01(*)  
0.005 
0.02 
0.01(*)  
0.01(*)  
0.01(*)  
0.01(*)  
0.1 
0.01(*) 
(*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.  
3.5.1 Amendment Rationale  
Although the use of fluxapyroxad on wheat and barley is not new, it is considered that poultry 
commodity MRLs are required to support the use of the compound on grain crops. The 
amendment establishes poultry MRLs to support new and existing uses of fluxapy roxad on 
these crops.   
14 • Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice New Zealand Food Safety  It is noted that the entry for the ‘edible offal’ MRL is being amended to change the name of 
the commodity to ‘mammalian offal’. This change is being made to align the terminology with 
that commonly used in the rest of the Notice. The value of the MRL for this commodity 
remains as previously promulgated.   
3.5.2 Good Agricultural Practice  
Fluxapyroxad is a pyrazole- carboxamide fungicide used to control disease in apples, pears, 
onions winter, squash, stone fruit, barley, and wheat crops, and  is used as a seed treatment 
on cereals. For  wheat and barley, the compound is applied at a rate of 75 gai/ha (co -
formulated with 150gai /ha mefentrifluconazole) as a single foliar spray in at least 150L 
water/ha on the first appearance of rusts, powdery mildew, leaf blotches, and leaf spots, up 
to the end of flowering. The withholding periods applied to this use are 42 days for grain and 
stubble/straw, and 28 days for green feed and silage.  
3.5.3 Residue Information  
The residue data for the use of  fluxaypyroxad  are sufficient to conclude that, when applied 
according to the proposed GAP use pattern and complying with the applicable withholding 
periods,  residues of parent fluxapyroxad should not exceed the limit of quantification ( 0.01 
mg/kg ) in any poultry commodity including eggs. The current residue definition of 
‘fluxapyroxad ’ remains appropriate for plant and animal commodities (for both GAP -
compliance and dietary intake assessment).  
3.5.4 Dietary Risk Assessment  
The HBGV  of 0.014  mg/kg bw/d,  and the stated dietary  intake residue definition, were 
considered appropriate for use in the  dietary intake  assessment.  Based on the residue profile 
expected from all horticultural and animal commodities , the NEDI is estimated to total less 
than 2% of the HBGV.  
MPI has therefore determined that the use of fluxapyroxad , when use according to the GAP 
specified above, is unlikely to pose any health risks from authorised use.   
3.5.5 Relevant International MRLs  
Country                                                        F ood Maximum Residue  
Level (mg/kg)  
Australia  Eggs                                                                         
Poultry meat [in the fat]  
Poultry, edible offal of  0.005  
0.01 
0.01 
Canada  Eggs                        
Meat of  poultry                               
Meat byproducts of poultry                                                     0.002  
0.01 
0.01 
Codex  Eggs                                                          
Poultry fats                     
Poultry meat                    
Poultry, edible offal of  0.02 
0.05 
0.02 
0.02 
European Union                  Poultry muscle              
Poultry fat                         
Poultry liver and kidney                      
Poultry edible offals  (other than liver and kidney)                                          
Eggs     0.02 
0.05 
0.02 
0.02 
0.02 
Japan                                   Poultry muscle                 
Poultry fat                            
Poultry liver, kidney and edible offal                               
Eggs                                   0.02 
0.05 
0.02 
0.02 
United States                                  All chicken and turkey commodities including 
eggs                             
0.01  
New Zealand Food Safety  Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice •  15 3.6 PROPOSAL TO  AMEND THE MRLS FOR  FOLPET  
It is proposed that the Notice entry for f olpet  is amended to set MRLs for animal commodities  
to support the GAP use of the compound on barley . 
The revised entry for folpet  in Schedule 1 of the Notice will read as follows. Changes are 
shown in bold:  
Compound 
Common Name  CAS#  Residue to which the maximum residue level 
applies  Food  Maximum Residue 
Level (mg/kg)  
Folpet  133-07-3 Plant commodities: Folpet  
Animal commodities: sum of folpet and phthalimide, 
expressed as folpet  Apples  
Barley grain  
Berries and other small 
fruits, except grapes and 
currants (black, red, white)  
Citrus Fruits  
Currants (black, red, white)  
Eggs  
Grapes  
Mammalian meat  
Mammalian offal  
Milk 
Poultry meat  
Poultry offal  10 
0.6 
  
15 
10 
30 0.05(*)  
25 
0.05(*)  
0.05(*)  
0.05(*)  
0.05(*)  
0.05(*)  
(*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.  
3.6.1 Amendment Rationale  
The MRL is being proposed to support an expansion of the use of folpet to barley . The 
proposed MRLs will manage the use of the compound as  a fungicide for the control of scald 
and Ramularia  in accordance with the use pattern proposed as GAP in New Zealand.   
3.6.2 Good Agricultural Practice  
Folpet is a non- systemic phthalimide fungicide which acts  by inhibiting microorganism cell 
division. It is currently used in the management of a broad range of fungal diseases in mostly 
fruit crops and ornamental plants in New Zealand.  For the additional use in barley , the 
compound is applied at a rate of 750  gai/ha as a preventative treatment when conditions 
favour infection, with reapplication in 3- 4 weeks if disease pressure continues or reinfection 
occurs. This use is restri cted to treatment before BBCH59, and attracts a withholding period 
of 28 days for grazing and feeding to livestock.  
3.6.3 Residue Information  
The residue data for the use of  folpet  on barley  are sufficient to conclude that, when applied 
according to the proposed GAP use pattern  and observing the restrictions and withholding 
period, residues of folpet  should not exceed 0.6 mg/kg  in barley grain . The current residue 
definition of ‘ folpet’  remains appropriate for plant commodities (for both GAP compliance and 
dietar y intake assessment).  
Because barley is used as an animal feed, the potential for residue transfer for animal 
commodities was evaluated. Animal metabolism study data in ruminants found that folpet is 
mainly excreted through uri ne and faeces, with the smal l amount of absorbed residue being 
extensively metabolised into phthalimide. The GAP compliance and dietary intake definitions 
for animal commodities will therefore be the sum of folpet and its metabolite phthalimide, 
expressed as folpet.  
The metabolism s tudy data also confirmed that, at the estimated New Zealand animal dietary 
burden, residues in ruminant animal commodities including milk can be expected to be 0.05 
mg/kg (the limit of quantification) or less when folpet is used according to GAP and observ ing 
the restriction and  withholding periods. Although no data exists to characterise the residue  
16 • Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice New Zealand Food Safety  profile of folpet in poultry, the very low (more than 100x less than that for ruminants) 
estimated dietary burden indicates that the same use of the limit of quantification as the 
MRLs to manage GAP for poultry commodities can apply. This approach is in line with that 
used in the EU  for animal commodity MRLs.   
3.6.4 Dietary Risk Assessment  
The HBGV  of 0.05  mg/kg bw/d,  and the stated dietary intake residue definitions, were 
considered appropriate for use in the dietary intake assessment.  Based o n the residue profile 
expected i n food from all horticultural and animal commodities , the NEDI is estimated to total 
less than 83% of the HBGV.  
MPI has therefore determined that  the use of folpet on barley , when use according to the 
GAP specified above, is unlikely to pose any health risks from authorised use.   
3.6.5 Relevant International MRLs  
Country                                                        Food  Maximum Residue  
Level (mg/kg)  
EU Barley  
All mammalian and poultry commodities, including milk and eggs                         1 
0.05 
3.7 PROPOSAL TO SET MRLS FOR  MEFENTRIFLUCONAZOLE  
It is proposed that MRLs are set for mefentrifluconazole to support the GAP use of the 
compound on wheat and barley crops.  Mefentrifluconazole is a new agricultural compound in 
New Zealand.  
There is currently no entry for mefentrifluconazole in the Notice. The new entry in Schedule 1 
of the Notice will read:  
Com pound Common 
Name  CAS#  Residue to which the 
maximum residue 
level  applies  Food  Maximum Residue 
Level (mg/kg)  
Mefentrifluconazole  1417782- 03-6 Mefentrifluconazole  Barley grain  
Eggs  
Mammalian fat  
Mammalian kidney 
Mammalian liver  
Mammalian meat  
Milk 
Poultry fat 
Poultry meat  
Poultry offal  
Wheat  grain  2 
0.01(*)  
0.1 
0.1 
0.3 
0.02 0.02 
0.02 0.01(*)  
0.02 
0.5 
(*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.  
3.7.1 Amendment Rationale  
The MRLs are being proposed to support the use of mefentrifluconazole as a fungicide for 
the control of rusts, powdery mildew, leaf blotches, and leaf spots in wheat and barley  in 
accordance with the use patterns proposed as GAP in New Zealand.  
3.7.2 Good Agric ultural Practice 
Mefentrifluconazole is a demethylation inhibitor  (DMI)  triazole  which acts by inhibiting sterol 
biosynthesis in fungal cell membranes. It is used to treats rust, powdery mildew, leaf blotch, 
and leaf spot infections as a single foliar spray  at a rate of 15 0gai / ha (co-formulated with 75 
gai/ha fluxapyroxad) , applied at the first appearance of disease up to the end of flowering.  
New Zealand Food Safety  Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice •  17 The withholding periods applied to this use are 42 days for grain and stubble/straw, and 28 
days for green feed and silage.  
    
3.7.3 Residue Information  
The residue data for the use of mefentrifluconazole in wheat and barley  were sufficient to 
conclude that, when applied as per the proposed GAP use pattern and complying with the 
applicable withholding period, residues of parent mefentrifluconazole should not exceed 0.5 
mg/kg in wheat grain or 2 mg/kg in barley grain. The residue and metabolism data confirmed 
that the primary residue in grain from treated crops was parent mefentrifluconazole, allowing 
the parent compound to be used as the GAP compliance and dietary intake residue 
definitions.  
The animal metabolism studies demonstrated that the primary residues for 
mefentrifluconazole in animal commodities were the parent compound and its metabolites 
M750F022 and M750F001 (1,2,4 -triazole). The dietary intake definition for animal 
commodities will therefore be mefentrifluconazole and its M750F022 and M750F001 
metabolites, expressed as mefentrifluconazole. Like plant commodities, the parent 
compound mefentrifluconazole will be sufficient to ensure GAP  compliance and will be used 
as the MRL residue definition.  
Animal r esidue transfer  data demonstrated that concentrations of mefentrifluconazole, when 
used according to GAP and observing the withholding periods,  should not exceed the 
proposed MRLs in mammalian tissues, poultry tissues, milk, and eggs.  
3.7.4 Dietary Risk Assessment  
The HBGV of 0.0 25 mg/kg bw/d, and the stated dietary intake residue definitions , were 
considered appropriate for use in the dietary intake assessment.  Based on the residue 
profile expected from all horticultural and animal commodities , the NEDI is estimated to total 
less than 5 % of the HBGV.   
MPI has theref ore determined that the use of mefentrifluconazole, when use according to the 
GAP speci fied above, is unlikely to pose any health risks from authorised use.  
3.7.5 Relevant International MRLs  
Country                                                          Food  Maximum Residue Level 
(mg/kg)  
Australia  Edible offal (mammalian)  
Eggs                               
Meat (mammalian) [in the fat]  
                           Milks       
Poultry meat [in the fat]                              
Poultry, edible offal of  0.02                                     
0.01 
0.02 
0.01 
0.01 
0.02 
Canada  Barley  
Wheat  
Eggs                                 
Fat of cattle, sheep, goats and horses  
Meat and fat of poultry  
Meat of cattle, sheep, goats and horses  
Meat fat, and meat byproducts of hogs  
Meat byproducts of cattle, sheep, goats, and horses  
Milk                                 
Milk fat                            4 
0.3 
0.01 
0.2 
0.01 
0.02 
0.01 
0.3 
0.02 
0.1 
   
18 • Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice New Zealand Food Safety  European Union  Barley  
Wheat  
All swine commodities  
Bovine and horse muscle             
Bovine and horse fat                           
Bovine and horse liver                     
Bovine and horse kidney                       
Bovine edible offals (other than liver and kidney)  
Sheep and goat muscle             
Sheep and goat fat                           
Sheep and goat liver                     
Sheep and goat kidney                       
Sheep and goat edible offals (other than liver and kidney)                         
Poultry muscle              
Poultry fat                         
Poultry liver                      
Poultry kidney                  
Poultry edible offals (other than liver and kidney)  
Cattle and horse milk                                          
Sheep and goat milk  
Eggs, all species                      0.6 
0.05 
0.01 
0.04 
0.2 
0.4 
0.1 
0.1 
0.06 0.4 
0.7 
0.3 
0.3 
0.015 
0.03 
0.03 0.03 
0.03 
0.02 
0.03 
0.015  
United States   Barley  
Wheat  
Cattle , goat, sheep and horse by products  
Hog by products                
Cattle, goat, sheep and horse fat                               
Hog fat                               
Cattle , goat, sheep and horse kidney                      
Hog kidney                    
Cattle , goat, sheep and horse liver                            
Hog liver                         
Cattle , goat, sheep and horse meat                             
Hog meat                       
Milk                                      
Chicken and turkey by products  
Chicken and turkey fat                     
Chicken and turkey kidney            
Chicken and turkey liver                     
Chicken and turkey meat                 
Chicken and turkey eggs                                4 
0.3 
0.3 
0.03 0.2 
0.015 
0.3 
0.03 
0.3 
0.03 
0.03 
0.01 
0.8 
0.01 
0.015 
0.01 
0.01 
0.01 
0.01 
3.8 PROPOSAL TO SET MRLS FOR  PROSULFOCARB 
It is proposed that MRLs are set for prosulfocarb to support the GAP use of the compound on 
potatoes. Prosulfocarb is a new agricultural compound in New Zealand.  
There is currently no entry for prosulfocarb in the Notice. The new entry in Schedule 1 of the 
Notice will read:  
Compound Common 
Name  CAS#  Residue to which the 
maximum residue level  
applies  Food  Maximum Residue 
Level (mg/kg)  
Prosulfocarb  52888- 80-9 Prosulfocarb (parent only)  Potato  0.01 (*)  
(*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.  
3.8.1 Amendment Rationale  
The MRLs are being proposed to support the use of prosulfocarb in potatoes in accordance 
with the use pattern proposed as GAP in New Zealand.   
New Zealand Food Safety  Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice •  19 3.8.2 Good Agricultural Practice  
Prosulfocarb  is a thiocarbamate herbicide used as pre -emergent herbicide that acts by 
inhibiting lipid synthesis in meristematic tissue  after application to soil and absorption by 
roots and leaves. In potatoes, prosulfocarb is  used for control of annual ryegrass and other 
grass and broadleaf weeds. The co mpound is applied to moist soil after planting at a rate of 
3.2 – 4.0 kgai /ha (co- formulated with 0.48 -  0.6 kgai/ha S -metolachlor) after the first 
cultivation but no later than 25% potato shoot emergence.  
Good agricultural practice for the proposed use o f prosulfocarb dictates that the compound 
must be applied after the first cultivation but no later than 25% potato shoot emergence. 
Accordingly, the associated WHP is “Not required when used as directed”.  
3.8.3 Residue Information  
The residue data for the use o f prosulfocarb in potatoes  were sufficient to conclude that, 
when applied as per the proposed GAP use pattern and complying with the applicable withholding period, residues of parent prosulfocarb are not expected in potatoes and should 
not exceed the limit of analytical quantification (0.01 mg/kg).  
Trial data evaluating the metabolism supports a ‘prosulfocarb (parent only) ’ residue definition 
for GAP compliance and dietary intake assessments for plant commodities.  This is consistent 
with the resid ue definitions in the EU and Australia.  
Animal commodity MRLs were not considered as potatoes are not a primary animal feed . 
3.8.4 Dietary Risk Assessment  
The HBGV of 0.0 035 mg/kg bw/d, and the stated dietary intake residue definition, were 
considered appropriate for use in the  dietary intake  assessment. Based on the residue profile 
expected in food from crops treated with prosulfocarb, the NEDI is estimated to total less than 1% of the HBGV.
  
MPI has therefore determined that the use of  prosulfocarb, w hen use according to the GAP 
specif ied above, is unlikely to pose any health risks from authorised use.  
3.8.5 Relevant International MRLs  
Country                                                          Food  Maximum Residue Level 
(mg/kg)  
Australia  Potato  0.01 
3.9 PROPOSAL TO AMEND  MRLS FOR  METOLA CHLOR  
It is proposed that the Notice entry for metolachlor  is amended to set a MRL to  support the 
GAP use of the compound on potatoes . 
The revised entry for metolachlor  in Schedule 1 of the Notice will read as follows. Changes 
are shown in bold:  
Compound 
Common Name  CAS#  Residue to which the maximum 
residue level  applies  Food  Maximum Residue 
Level (mg/kg)  
Metolachlor  51218- 45-2 Metolachlor  and its enantiomers, 
expressed as metolachlor  Asparagus  
Potatoes Pumpkins  
Sweetcorn 
Summer squash 
Winter squash  0.05(*)  
0.01(*)  
0.05(*)  
0.05(*)  
0.05(*)  
0.05(*)  
(*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.   
20 • Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice New Zealand Food Safety  3.9.1 Amendment Rationale  
The MRL is being proposed to support the use of S -metolachlor as a pre -emergent herbicide 
for control of annual ryegrass and other grass and broadleaf weeds in potatoes in 
accordance with the use pattern proposed as GAP in New Zealand.  
3.9.2 Good Agricultural Practice  
S-metolachlor belongs to the chloroacetanilide group of compounds,  which acts by inhibiting 
chlorophyll and protein synthesis in target plants. The compound is  most active during 
germination and seedling emergence from the soil. S -metolachlor is an established pre -
emergent selective grass herbicide with current uses in maize, sweetcorn, asparagus, pumpkins and squash. For the proposed use in potatoes, the compound is applied to moist 
soil after planting at a rate of 0.48 -  0.6 kgai/ha (co- formulated with 3.2 - 4.0 kgai /ha 
prosulfocarb) after the first cultivation but no later than 25% potato shoot emergence.  
Good agricultural practice for the proposed use of S -metolachlor dictates that the compound 
must be applied after the first cultivation but no later than 25% potato shoot emergenc e. 
Accordingly, the associated WHP is “Not required when used as directed”.   
3.9.3 Residue Information  
The residue data for the use of S-metolachlor in potatoes  were sufficient to conclude that, 
when applied as per the proposed GAP use pattern and complying wit h the applicable 
withholding period, residues of metolachlor  are not expected in potatoes and should not 
exceed 0.01(*) mg/kg.  
Trial data evaluating the metabolism supports the residue definition of  ‘metolachlor’ for GAP 
compliance and dietary intake assessments for plant commodities , which includes S -
metolachlor as well as the R - and RS - enantiomers. Because  mixed isomer formulations of 
metolachlor are no longer registered in New Zealand, the residue definition is being 
amended to ensure it is clear that the enantiomers are captured. This is to reflect the use of 
S-metolachlor as an agricultural compound in its own right in New Zealand, while recognising 
the similarities between the enantiomers and t he analytical methods used in the New 
Zealand residue monitoring programme.   
Animal commodity MRLs were not considered as potatoes are not a primary animal feed . 
3.9.4 Dietary Risk Assessment  
The HBGV of 0.0 7 mg/kg bw/d, and the stated dietary intake residue def inition, were 
considered appropriate for use in the  dietary intake  assessment. Based on the residue profile 
expected i n food from crops treated with S -metolachlor,  the NEDI is estimated to total less 
than 0.1% of the HBGV.   
MPI has therefore determined tha t the use of metolachlor , when use according to the GAP 
specified above, is unlikely to pose any health risks from authorised use.  
3.9.5 Relevant International MRLs  
Country                                                          Food  Maximum Residue Level 
(mg/kg)  
Australia  Potato  0.01 
Note: the  Australian  MRLs capture both metolachlor and S -metolachlor, and the residue definition is metolachlor .  
New Zealand Food Safety  Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice •  21 3.10 PROPOSAL TO  AMEND THE MRLS FOR  TEBUCONAZOLE  
It is proposed that the Notice entry for tebuconazole is amended to set MRLs for animal 
commodities to support the GAP use of the compound on fodder and sugar beets used as 
animal feed . 
The revised entry for tebuconazole in Schedule 1 of the Notice will read as foll ows. Changes 
are shown in bold:  
Compound 
Common 
Name  CAS#  Residue to which the 
maximum residue level 
applies  Food  Maximum Residue 
Level (mg/kg)  
Tebuconazole 107534- 96-3 Tebuconazole Bulb vegetables  
Cereal grains  
Eggs  
Mammalian fat  
Mammalian kidney 
Mammalian liver  
Mammalian meat  
Milk 
Peas  
Poultry  fat 
Poultry meat  
Poultry offal  
Stone fruits  0.2 
0.05(*)  
0.01(*)  
0.01(*)  
0.01(*)  
0.07 
0.01(*)  
0.01(*)  
0.2 
0.01(*)  
0.01(*)  
0.01(*)  
1 
(*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.  
3.10.1  Amendment Rationale  
The MRLs are being proposed to support an expansion of the use of tebuconazole to fodder 
beets for animal consumption, in accordance with the use pattern proposed as GAP in New 
Zealand.  
3.10.2  Good Agricultural Practice  
Tebuconazole is a DMI triazole f ungicide which inhibits fungal cell wall synthesis. The 
compound is used on its own or with other compounds for the control of fungal diseases in 
peas, onions, stone fruit, pome fruit, kiwifruit, grapes, and cereal crops, as well as ryegrass 
and seed crops  and on pasture. The new use has been proposed to manage rust, powdery 
mildew, and Cercospora infections in fodder beet crops grown solely for animal consumption. 
For this additional use , the compound is applied as a foliar spray at a rate of 200 gai/ha (c o-
formulated with 120 gai/ha azoxystrobin) when disease first becomes active in the crop, and 
no sooner than 14 days later. A withholding period of 28 days applies to this use for both 
harvest and grazing of the crop.  
3.10.3  Residue Information  
To establish the animal commodity MRLs for this compound, data was reviewed for both the 
new use in fodder beets as well as existing uses in cereal grains and pasture. This was to 
ensure the animal commodity MRLs are reflective of all GAP uses of the compound.  
The residue data for the use of  tebuconazole in crops used as animal feed were sufficient  to 
conclude that, when used according to the proposed and existing GAP use patterns , 
residues of tebuconazole should not exceed 0.07 mg/kg in mammalian liver or the limit of 
quan tification (0.01 mg/kg) in all other animal commodities. The animal  metabolism 
confirmed that the current plant commodity residue definition of ‘ Tebuconazole ’ is 
appropriate to use as the residue definition for  animal commodities  (for both GAP -
compliance and dietary intake assessment).   
22 • Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice New Zealand Food Safety  3.10.4  Dietary Risk Assessment  
The HBGV  of 0.0 2 mg/kg bw/d, and the stated dietary intake residue definition, were 
considered appropriate for use in the dietary intake assessment.  Based on the residue profile 
expected from all hort icultural and animal commodities,  the NEDI is estimated to total less 
than 2% of the HBGV. 
MPI has therefore determined that the use of  tebuconazole, when use according to the GAP 
specified above, is unlikely to pose any health risks from authorised use.   
3.10.5  Relevant International MRLs  
Country                                                        Food  Maximum Residue  
Level (mg/kg)  
Australia  Edible offal (mammalian)  
Eggs  
Meat (mammalian) [in the fat]  
Milks  
Poultry meat  
Poultry, edible offal of  0.5 
0.1 
0.1 
0.05 
0.1 
0.5 
Canada Meat of cattle, sheep, horses, goats and hogs  
Meat byproducts of cattle, sheep, horses, goats and hogs  
Milk  
Meat of poultry  
Meat byproduct of poultry  
Eggs  0.2 
0.2 
0.1 
0.1 
0.1 
0.1 
Codex  Edible offal (mammalian)                        
Eggs  
Meat (from mammals other than marine mammals)  
Milks  
Poultry meat  
Poultry, edible offal of  0.2 
0.05 
0.05 0.01 
0.05 
0.05 
EU Swine, bovine, sheep, goat, and horse muscle  
Swine, bovine, sheep, goat, and horse fat  
Swine, bovine, sheep, goat, and horse liver  
Swine, bovine, sheep, goat, and horse kidney  
Swine, bovine, sheep, goat, and horse edible offals (other than liver 
and kidney)  
Poultry muscle, fat, liver, kidney, and edible offals (other than liver 
and kidney)  
Milk 
Eggs  0.1 
0.1 
0.2 
0.2 
 
0.2 
 
0.1 
0.02 
0.1 
Japan Cattle, pig, and other terrestrial mammal muscle  
Cattle, pig, and other terrestrial mammal fat  
Cattle, pig, and other terrestrial mammal liver  
Cattle, pig, and other terrestrial mammal kidney  
Cattle, pig, and other terrestrial mammal edible offal 
Milk 
All chicken and other poultry commodities including eggs  0.05 
0.05 
0.2 
0.2 
0.2 
0.01 
0.05 
United States   Cattle, goat, horse, and sheep by products  
Cattle, goat, horse, and sheep kidney  
Cattle, goat, horse, and sheep liver  
Milk 0.2 
0.2 
0.2 
0.1 
 
   
New Zealand Food Safety  Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice •  23 3.11 PROPOSAL TO  EXEMPT 1 -TRIACONTANOL FROM CO MPLIANCE WITH A 
MRL   
It is proposed that 1- triacontanol is exempt from compliance with an MRL by amendment to 
Schedule 2 of the Notice. The compound is a long -chain fatty alcohol which is naturally 
present in plant cuticle waxes,  and used as plant growth regulator on pasture. 1- triacontanol 
is readily metabolised by grazing animals with no accumulation in animal tissues. The NZ 
EPA has evaluated this substance and concluded that a health based guidance value was 
not required to manage dietary exposure.  
The proposed entry in Schedule 2 will read as follows :  
Substance CAS#  Condition  
1-Triacontanol  593-50-0 When used as a plant growth regulator on  past ure. 
3.12 PROPOSAL TO  EXEMPT EUGENOL FROM COMPLIANCE WITH A MRL  
It is proposed that eugenol  is exempt from compliance with an MRL by amendment to 
Schedule 2 of the Notice  when used as a fungicide on grapevines.  Eugenol is an 
allylbenzene compound extracted from cloves and other herbs and spices, and has been 
shown to have fungicidal activity. Data were provided confirming residue levels of eugenol 
and its toxic impurity methyl -eugenol were not persistent and not likely to be distinguishable 
from ba ckground levels  when used on grapevines . 
The proposed entry in Schedule 2 will read as follows :  
Substance CAS#  Condition  
Eugenol  97-53-0 When  used as a  fungicide on  grapevines.  
3.13 PROPOSAL TO  EXEMPT GERANIOL FROM  COMPLIANCE WITH A MRL  
It is proposed that geraniol  is exempt from compliance with an MRL by amendment to 
Schedule 2 of the Notice when used as a fungicide on grapevines.  Geraniol is a 
monoterpene alcohol which is naturally occurring in rose oil and a number of other essential 
oils derived from plants.  Like eugenol, data confirmed post -treatment residue levels of 
geraniol in grapes were not persistent and were not likely to be disting uishable from 
background levels.  
The proposed entry in Schedule 2 will read as follows :  
Substance CAS#  Condition  
Geraniol  106-24-1 When  used as a fungicide on  grapevines.  
3.14 PROPOSAL TO  AMEND THE EXEMPTION FOR HYDROGEN  PEROXIDE  
Hydrogen peroxide is currently subject to an exemption from compliance with a MRL in 
Schedule 2 of the Notice when used as a spray -on bactericide or fungicide in fruit. It is 
proposed that the exemption is amended to also allow its use for the same purpose on 
vegetable crops without the need to comply with a MRL. Because hydrogen peroxide is of  
24 • Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice New Zealand Food Safety  low oral toxicity, is not mutagenic and is not carcinogenic, the proposed amendment to 
include vegetables is unlikely to produce residues that will  negatively  impact  food safety.  
The revised entry in Schedule 2  will read as follows . The c hanges are in bold:  
Substance CAS#  Condition  
Hydrogen peroxide  7722- 84-1 When used as a spray -on fungicide and  bactericide  on 
fruits  and vegetables.  
3.15 PROPOSAL TO  EXEMPT THYMOL FROM C OMPLIANCE WITH A MRL  
It is proposed that thymol  is exempt from compliance with an MRL by amendment to 
Schedule 2 of the Notice when used as a fungicide on grapevines.  Thymol is a 
monoterpenoid phenol found in essential oils extracted from thyme as well as some other 
plants, and has been shown to have fungicidal activity. Post -treatment residues of thymol 
were not persistent in grapes and were not likely to be distinguishable from background 
levels.  
The proposed entry in Schedule 2 will read as follows :  
Substance CAS#  Condition  
Thymol  89-83-8 When us ed as a fungicide on grapevines  
3.16 PROPOSAL TO  REMOVE  THE EXEMPTION FOR D IDECYL DIMETHYL 
AMMONIUM CHLORIDE  
It is proposed that the exemption for d idecyl dimethyl ammonium chloride, also known as 
DDAC,  is removed from Schedule 2 of the Notice. This is because there are no approved 
uses  of this compound under the Agricultural Compounds and Veterinary Medicines Act 
1997.   
The following entry  will be deleted from Schedule 2:  
Substance CAS#  Condition  
Didecyl Dimethyl Ammonium Chloride  7173- 51-5 When applied as a fungicide on fruits and vegetables  
3.17 PROPOSAL TO  AMEND THE EXEMPTION FOR VACCINE AND DIAGNOSTIC 
ANTIGENS  
It is proposed that  the exemption from compliance with a MRL for vaccine and diagnostic 
antigens  in Schedule 3 of the Notice is amended. The current exemption allows for the use of 
microorganism -derived compounds to be used as vaccine antigens and as antigens in 
diagnostic t ests for the management of diseases in animals. It is proposed that the condition 
of exemption is amended to make it clear that bacterial cell wall components may be used as 
immunostimulants as well as vaccine antigens targeting a specific disease .  
Becaus e bacterial cell wall components are already captured in the phrasing of the 
exemption, this extension only addresses how the components may be used in veterinary 
medicines. As such, the change is not expected to pose any additional  residue risks in 
commodities from treated animals .   
New Zealand Food Safety  Proposals to Amend the New Zealand (Maximum Residue Levels for Agricultural Compounds) Food Notice •  25 The revised entry in Schedule 3 will read as follows. The c hanges are in bold:  
Substance CAS#  Condition  
Vaccine and Diagnostic Antigens  
This exemption applies when the 
antigen is derived from a viable or non-viable microorganism.  n/a  When derived from whole attenuated or killed 
microorganisms, inactivated microorganisms or fractions 
of microorganisms, or other biological -derived proteins , 
and used as a veterinary medicine.  Includes bacterial 
cell wall components used as an immunostimulant