SDA MAPA ORDINANCE NO. __, ___________ , 2023  
Approves the guidelines of the National 
Bovine Spongiform Encephalopathy 
Program - PNEEB for the application of 
official prevention and surveillance 
measures and for maintaining the 
negligible risk status  of bovine spongiform 
encephalopathy - BSE in the country.  
 
THE SECRETARY OF AGRICULTURAL DEFENSE,  using the attribution conferred by art. 87, 
item II, of the Constitution, in view of the provisions of Decree No. 24.548, of July 3, 
1934, Law No. 1.283, from December 18, 1950, Law No. 7.889, from November 23, 1989,  
Decree No. 5.741, from March 30, 2006, Decree No. 9.013, from March 29, 2017, Decree 
10.139, from November 28, 2019, Law 14.515, from December 29, 2022, in art. 22 and 
49 of Decree No. 11.332, from January 1, 2023  in addition to the contents in process 
No. XXXXXXXXXXXXXXX, decides to:  
Art. 1 Approve the guidelines of the National Bovine Spongiform Encephalopathy 
Program - PNEEB for the application of official prevention and surveillance measures 
and for maintaining the Negligible Risk Status  of bovine spongiform encephalopathy in 
the country.  
 
CHAPTER I  
ORGANIZATIONAL STRUCTURE, FUNDAMENTALS AND STRATEGIES  
 
Section I  
Fundamentals, strategies,  and scope  
Art. 2 The National Bovine Spongiform Encephalopathy Program  (PNEEB) aims 
to: 
I - prevent the entry of the classical Bovine Spongiform Encephalopathy ( BSE) 
agent into the national territory;  
II - implement a surveillance system for the detection of classical  BSE cases;  
III - avoid recycling of the BSE agent in the country's bovine  population.  
Art. 3 PNEEB strategies include : 
I - shared management, between the public and private sector, of the execution 
of the actions that make up the BSE surveillance system in the country;  
II - import control and monitoring of imported bovine ; 
III - control of the import of ingredients of ruminant origin, considered of relevant 
risk for the transmission of the BSE agent;  
IV – control and inspection in establishments that manufacture products  
intended for ruminants and monitoring of their products, to prevent contamination with 
products of  ruminant origin; and  V - alignment of actions with public health and animal health education and 
communication programs.  
Art. 4 For the execution of the PNEEB, the provisions of this Ordinance, the 
technical data sheet, the manuals and the surveillance and contingency plans  made 
available on the website of the Ministry of Agriculture  and Livestock and the regulations 
of the state animal health agencies must be observed regarding:  
I - the management of the national program in the Federative Units;  
II - the implementation  of the components of the surveillance system for bovine 
spongiform encephalopathy ;  
III – the investigation of cases, the collection, the sending of samples and the 
laboratory diagnosis of bovine spongiform encephalopathy ; 
IV - good livestock practices ; 
V - education and communication  in animal health ; 
VI - the adoption of sanitary measures in bovin e slaughterhouses or processing 
establishments, in establishments that process bovine waste;  
VII  - the control and inspection  of national  and international transit of ruminants  
and their products ; 
VIII – actions to respond to the zoosanitary  emergency ; and  
IX  - the other actions of the National Bovine Spongiform Encephalopathy 
Program - PNEEB.  
 
CHAPTER II  
SURVEILLANCE PROCEDURES  
 
Section I  
General Procedures  
Art. 5 The target population for surveillance  of Bovine Spongiform 
Encephalopathy is represented by bovine  of any age that meet  the clinical spectrum of 
the disease.  
. The clinical spectrum of Bovine Spongiform Encephalopathy is characterized by 
bovine  showing progressive neurological and behavioral clinical signs and bovine  found 
in recumbency  or dead with a compatible clinical history.  
Art 6 The carcasses, parts of carcasses, organs, viscera and other animal parts, 
whether  edible or not, and the waste  from  bovine  submitted to sample collection 
within the scope of the surveillance of Bovine Spongiform Encephalopathy referred to 
in this Ordinance are considered unfit for human and animal consumption and  must 
be destroyed for any purpose.  
§ 1 The destruction provided for in the caput  must be carried out by 
incineration or autoclaving in a proper  equipment, burial, or other treatment approved by the Department of Animal Health, of the Secretariat of Agricultural 
Defense.  
§ 2 The residues  resulting from the destruction referred to in § 1 must be 
submitted to burial or another destination approved by the Department of Animal 
Health -DSA, of the Secretariat  of Agricultural Defense, in order to prevent ruminants 
from accessing such waste . 
Art 7 It is responsibility of  the official inspection service to adopt other actions 
established in animal health legislation.  
 
 
Section II  
Notification  
Art. 8 The notification of suspected Bovine Spongiform Encephalopathy to the 
official veterinary service is mandatory for any citizen.  
§ 1 The notification referred to in the caput  must occur within a maximum period 
of 24 (twenty -four) hours from the identification of the suspect through  an electronic 
system developed by the Ministry of Agriculture and Livestock or directly to the Animal 
Health Executing Body of the Federative Unit where the bovine  is under  
Art. 9 The farmer or person responsible for the bovine animal suspected of 
having BSE must keep it isolated until the conclusion of the investigation or until a 
decision  by the official veterinary service.  
 
 
Section III  
 
Investigation  
Art. 10 The official veterinary service is responsible for conducting the clinical -
epidemiological investigation of Bovine Spongiform Encephalopathy, in order to adopt 
the measures defined in the technical data sheet of the disease, in the surveillance and 
conting ency plan established by the Department of Animal Health - DSA, of the 
Secretariat of Agricultural Defense - SDA.  
§ 1 When identifying a  bovine  with signs of the clinical spectrum of Bovine 
Spongiform Encephalopathy, the veterinarian of the private sector must immediately 
notify the official veterinary service to carry out the investigation and the collection of 
samples for BSE.  
§ 2 The official veterinary service must comply with notifications of suspected 
bovine spongiform encephalopathy - BSE within a maximum period of 24 (twenty -four) 
hours from the notification.  
§ 3 The investigation carried out by the official veterinary service must consider 
the clinical aspects, epidemiological elements,  and laboratory tests relevant  to the 
investigation of cases of Bovine Spongiform Encephalopathy, according to the criteria 
established in the technical data sheet  of the Department of Animal Health - DSA, of the 
Secretariat of Agricultural Defense - SDA.  Art. 11 Samples of material collected from bovine suspected of bovine 
spongiform encephalopathy - BSE must be sent immediately to the official national 
reference laboratory, defined by the General Coordination of Laboratories, of the 
Department of Technical Servic es of the Secretariat of Agricultural Defense of the 
Ministry of Agriculture and Livestock.  
Art. 12 The adoption of measures mentioned in art. 10,  in the establishment 
where the suspected bovine animal is located, or in  any epidemiological unit potentially 
exposed to the agent of Bovine Spongiform Encephalopathy must be defined by the 
official veterinary service, in compliance with the  investigations carried out  and  the 
potential  impacts on animal health and public health, or as established in the contingency 
plans of the Department of Animal Health, the Department of Agricultural Defense of 
the Ministry of Agriculture and Livestock.  
§ 1 The measures must be maintained until the classic Bovine Spongiform 
Encephalopathy is discarded or, in case of its confirmation, until all relevant measures, 
provided for in the contingency plan, are completed.  
§ 2 The official veterinary service is responsible for suspend ing the sanitary 
measures mentioned in the Caput of this article.  
 
 
Section II  
Surveillance procedures in rearing farms  
Art. 13 The surveillance of Bovine Spongiform Encephalopathy in rearing farms  
can be carried out by the official veterinary service and by veterinarians from the private 
sector and  must be directed to the target population described in art. 5, following the 
criteria and procedures defined by the Department of Animal Health - DSA, of the 
Secretariat of Agricultural Defense - SDA.  
Art. 14 Suspected bovine  must be su bmitted  clinical and epidemiological 
evaluation for the  characteriz ation  of the clinical spectrum of Bovine Spongiform 
Encephalopathy, according to the criteria defined by the Department of Animal Health 
- DSA, of the Secretariat of Agricultural Defense - SDA.  
Single Paragraph . Samples for diagnosis of Bovine Spongiform Encephalopathy 
should be sent  immediately to the official reference laboratory specified by the Ministry 
of Agriculture and Livestock.  
 
 
 
 
Section III  
Surveillance procedures in slaughterhouses  
Art 15 The surveillance of Bovine Spongiform Encephalopathy in bovine  
slaughter establishments will be carried out by the official inspection service  and must 
be directed to the target population described in art. 5 , following the criteria and procedures defined by the Department of Animal Health of the Secretariat of 
Agricultural Defense .  
Art 16 The veterinarian of the official inspection service must collect  a sample 
for the laboratory diagnosis of bovine spongiform encephalopathy - BSE when 
identifying  a bovine  with an association of behavioral or neurological changes 
compatible with the disease.  
Single Paragraph . Those responsible for the slaughterhouses must provide 
equipment and materials  necessary for the collection, packaging  and preservation of 
samples, in addition to providing means for the prompt delivery  of samples to the 
national reference laboratory, as described in art. 11 of this Ordinance.  
  
CHAPTER III  
RISK MITIGATION MEASURES  
Section I 
Control measures for imported bovine  
Art. 17 All imported bovine , except those destined for immediate slaughter, must 
be individually identified in Brazil, and inserted into a public system that allows their 
traceability until the end of their lives.  
Single Paragraph . The person responsible for the animals mentioned in the caput 
must immediately notify the official veterinary service of the movement, death, 
suspicion of illness, escape, theft,  or robbery and present a copy of the police incident 
when the last two situations  are met.  
 
Art. 18  The permanently imported  bovines , for any purpose other than 
immediate slaughter, in whose country of origin there is an indigenous  case of classical 
bovine spongiform encephalopathy - classic BSE, must be monitored by the official 
veterinary service in accordance with the procedures described in the surveillance plans 
and manuals made available by the Department of Animal Health - DSA, of the 
Departmen t of Agricultural Defense - SDA, on the website of the Ministry of Agriculture 
and Livestock.  
 
Section II  
From establishments manufacturing ingredients and additives of animal 
origin for the feeding of ruminants  
 
Art. 19 The production, marketing and use, in feed s for  ruminants, of products 
containing in their composition, ingredients and additives of ruminant origin intended 
for the feeding of ruminants are prohibited throughout the national territory.  
 
Art. 20 The following products are excluded from the prohibitions provided for 
in art. 19:  
I - milk and milk products;  II - calcined bone meal;  
III - gelatin and collagen prepared exclusively from hides and skins;  
IV - fetal blood;  
V - fats and fat derivatives of ruminant origin  whose maximum content of 
insoluble impurities does not exceed 0.15% of their weight ; and  
VI - dicalcium phosphate of animal origin, free of ruminant proteins and fats.  
§ 1 The list of ingredients and additives of ruminant origin  authorized to be used 
in feeds for ruminants  may be amended, at the discretion of the Department of Animal 
Health, by risk analysis.  
§ 2 The absence of proteins and fats of ruminants in ingredients and additives of 
animal origin used in feeds for ruminant s must be proven by auditable means, without 
prejudice to other legal requirements.  
Art. 21 Products for ruminant feed are subject to inspection analysis, at all links 
in the production chain, for the  identification of prohibited ingredients and additives of 
ruminant origin.  
 
 
Section III  
Products  from ruminants used in the manufacture of products for veterinary 
use 
 
Art. 22 The production, marketing and use of products for veterinary use 
intended for ruminants containing ruminant products  in their formulation are 
prohibited.  
 
Single paragraph  Excluded from the prohibitions mentioned in the caput are the 
products provided for in art. 20.  
 
Art. 23 Products for veterinary use for ruminants are subject to inspection 
analysis, in all links of the production chain, for the  identification of prohibited products . 
 
Section  IV 
The use of ruminant proteins or fats as organic fertilizer  
 
Art. 24 The use of organic fertilizers containing proteins or fats from ruminants 
must follow the rules in force in specific legislation.  
 
 
 
Section V 
Inspection of products intended for ruminant feed in rearing farms  
 
Art. 25 The inspection of products intended for the feeding of ruminants in 
rearing farms  must follow the procedures described in the manuals made available by the Department of Animal Health of the Department of Agricultural Defense on the 
website of the Ministry of Agriculture, Livestock and Supply.  
§ 1 In case of a positive and conclusive result of analysis of ruminant feed for the 
detection of proteins or fats of ruminant origin, the official animal health service in the 
federative units must apply the sanction provided for in specific legislation.  
 
 
Section VI 
Control measures in meat and meat products establishments and in 
establishments of ingredients and additives of animal origin for animal feed  
 
Art. 26 The following tissues from bovine s are considered with a higher risk of 
infectivity for bovine spongiform encephalopathy - BSE:  
I - distal ileum, comprising the last 70 (seventy) centimeters, of animals of any 
age; and  
II - encephalus , eyes and spinal cord of animals over 30 (thirty) months of age.  
Art. 27   It is mandatory to adopt the following measures to reduce infectivity for  
bovine spongiform encephalopathy - BSE:  
I - in slaughter establishments: the removal, segregation and destruction of the 
products and animal parts specified in art. 26, of all slaughtered bovine ; 
II - in establishments that process  ruminant waste:  
a) prohibition of the use of bovine products and parts described in art. 26 in the 
production of protein  meal;  
b) the reduction of raw material particles, before sterilization, by means of 
proper  equipment, with particles not exceed ing five (5) centimeters on any of its faces, 
except in the case of flat bones,  which it is not possible to obtain this dimension on all 
faces;  
c) sterilization at a temperature not lower  than 133°C, for at least 20 (twenty) 
minutes, without interruption, at a (absolute) pressure of not less than 3 (three) bar, 
produced by saturated steam; or  
d) another procedure approved by the Department of Animal Health of the 
Secretariat of Agricultural Defense to replace those described in items "b" and "c" of 
item II of art. 27, provided that its equivalence or superiority in relation to the 
procedures to  be replaced is proven.  
§ 1 Bovine  slaughter establishments and establishments processing  ruminant 
waste  are exempt from the adoption of measures to reduce infectivity for bovine 
spongiform encephalopathy - BSE described in art. 27 as long as Brazil maintains its 
status of recognition by the World Organization for Animal Health as a country at 
negligible risk  for BSE.  
§ 2 The exemption referred to in § 1 does not apply to cases in which actions 
must be taken to meet the requirements of international sanitary certification of 
products, according to the specific standard of the Department of Inspection of Products 
of Animal Origin - DIPOA.  Art 30 The Secretariat of Agricultural Defense may establish additional measures 
to those provided for in art. 27, covering slaughterhouses, animal waste processing 
establishments and other members of the production chains of the agricultural sector, 
in ca se of change in the epidemiological situation of Brazil for bovine spongiform 
encephalopathy - BSE.  
Art. 31 The establishments manufacturing ingredients of animal origin intended 
for the feeding of ruminants must adopt validated operating procedures in order to 
prevent cross -contamination between non -ruminant and ruminant source materials.  
Single Paragraph . The procedures described in art. 31 must cover all stages of 
production, from the receipt of waste to the shipment and transportation of finished 
products.  
Art. 32 Mandatory labeling information regarding restrictions on use for 
ruminants must follow specific standards.  
 
CHAPTER IV  
DIAGNOSIS, ANALYTICAL METHODS AND OFFICIAL RESULTS  
 
Art. 33 The diagnostic tests and recognized analytical methods for the definition 
of a confirmed case of BSE will be described in the manuals, technical files and 
surveillance plans made available by the Department of Animal Health, of the 
Department of Ag ricultural Defense, on the website of the Ministry of Agriculture and 
Livestock.  
Art. 34 Official results of diagnostic tests for BSE are those issued by official 
laboratories of the Ministry of Agriculture and Livestock and  by international reference 
laboratories of the World Organization for Animal Health.  
 
CHAPTER V  
EDUCATION AND COMMUNICATION IN ANIMAL HEALTH AND MANAGEMENT 
OF THE NATIONAL BOVINE SPONGIFORM ENCEPHALOPATHY PROGRAM - 
PNEEB  
 
Section I  
Animal health education and communication  
 
Art. 35 The animal health education and communication actions related to 
bovine spongiform encephalopathy - BSE, carried out by the official veterinary service 
as instruments of public animal health policy, aim to:  
I - integration and commitment of agents of the agricultural production chains 
within the scope of the National Bovine Spongiform Encephalopathy Program - PNEEB;  
II - raising awareness for the adoption of standards related to the National Bovine 
Spongiform Encephalopathy Program - PNEEB;  
III - implementation and updating of strategies to be adopted in the surveillance 
and contingency plans and the National Bovine Spongiform Encephalopathy Program - 
PNEEB;  VI - contribution to the achievement of the surveillance  objectives of bovine 
spongiform encephalopathy - BSE.  
. Animal health education comprises the continuous and structured process of 
production and dissemination of knowledge by public and private agents, within the 
scope of agriculture, and by society.  
Art. 36 Animal health education and communication actions must be aligned 
with the strategies established by the Secretariat of Agricultural Defense and must be 
based on transparency, coherence and opportunity.  
Art. 37 Animal health education and communication actions should be 
developed, whenever possible, in an articulated way between the public and private 
sectors, in the form of programs, plans and projects.  
 
Section II  
Management of the National Bovine Spongiform Encephalopathy Program - 
PNEEB  
 
Art 38 The Department of Animal Health, of the Secretariat of Agricultural 
Defense, may appoint members to compose a National Management Team of the 
National Bovine Spongiform Encephalopathy Program - PNEEB, of an advisory nature.  
§ 1 The National Management Team must observe, in its composition, the 
criteria for sharing responsibilities between the various segments of the public and 
private sector.  
§ 2 The National Management Team is responsible for promoting the planning, 
monitoring the execution and carrying out the evaluation of the National Bovine 
Spongiform Encephalopathy Program - PNEEB, according to the following criteria:  
I - meeting your goals ; 
II - achievement of scheduled goals;  
III - execution of the planned actions;  
IV - adequate management;  
V - financial support; and  
VI - respect for fundamental principles and strategic guidelines.  
 
§ 3 The official animal health services in the federative units, together with the 
local private sectors, may constitute and maintain State Management Teams to act in 
line with the National Management Team to promote planning, monitor execution and 
carry out the evaluation of the National Bovine Spongiform Encephalopathy Program - 
PNEEB in the respective federativ e units.  
 
CHAPTER VI  
 FINAL PROVISIONS  
Art 39 Revoke  the table of § 8, of art. 17, of SDA Normative Instruction No. 61 of 
07.08.2020.  
Art. 40 Art. 2nd Normative Instruction Map No. 5, of 1st. 03.2002, becomes 
effective with the following wording: "The enzootic paraple gia of sheep (scrapie) is 
included in the surveillance system for neurological syndromes of domestic herbivores, 
as described in the technical files, manuals and surveillance plans made available by the 
Department of Animal Health, of the Department of Agricu ltural Defense, on the 
website of the Ministry of Agriculture and Livestock." (NR)  
Art. 41 The following acts are hereby revoked :  
I - Normative Instruction (SDA) No. 18, of February 15, 2002, published in the 
Federal Official Gazette on February 19, 2002, section 1, page 1;  
II - Normative Instruction (SDA) No. 69, of September 23, 2003, published in the Federal 
Official Gazette on September 24, 2003, Section 1, page 7;  
III  - Normative Instruction (Map) No. 18, of December 15, 2003, published in the 
Federal Official Gazette on December 24, 2003, section 1, pages 21 and 22;  
IV  - Normative Instruction (Mapa) No. 8, of March 25, 2004, published in the 
Federal Official Gazette on March 26, 2004, section 1, page 5;  
V  - Normative Instruction (Mapa) No.  41, of October 8, 2009, published in the 
Federal Official Gazette on October 9, 2009, section 1, pages 8 and 9;  
VI  - Normative Instruction (Mapa) No. 42, of August 30, 2011, published in the 
Federal Official Gazette on August 31, 2011, section, page 2;  
VII  - Normative Instruction (mapa) No. 44, of September 17, 2013, published in 
the Federal Official Gazette on September 18, 2013, section 1, page 16;  
VIII - Normative Instruction (SDA) No. 13, of May 14, 2014,  published in the 
Federal Official Gazette on May 22, 2014, section 1, pages 8 to 10; and  
IX  - Normative Instruction (Mapa) No. 31, of September 3, 2014,  published in 
the Federal Official Gazette on September 4, 2014, section 1, page 8;  
X- Normative Instruction (Map) No. 1, of February 20, 2015, published in the 
Federal Official Gazette on February 24, 2015, section 1 page 3;  
XI  - item V of art. 2 and § 3 of art. 24 of Normative Instruction (Mapa) No. 48, of 
October 17, 2019, published in the Federal Official Gazette on October 18, 2019, section 
1, pages 73 and 74;  
IV - SDA Ordinance No. 651, of September 8, 2022, published in the Federal 
Official Gazette on September 12, 2022, section 1, pages 5 and 6.  Art. 42. This Ordinance enters into force on January 1, 2024.