G/TBT/N/USA/1171/Add.2  
 
6 July 2022  
(22-5200) Page: 1/2 
Committee on Technical Barriers to Trade  Original: English  
 
NOTIFICATION  
Addendum  
The following communication , dated  6 July 2022, is being circulated at the request of the delegation 
of the United States of America . 
 
_______________  
 
 
Title:  Significant New Uses of Chemical Substances; Updates to the Hazard Communication Program 
and Regulatory Framework; Minor Amendments to Reporting Requirements for Premanufacture 
Notices  
 
Reason for Addendum:  
[ ] Comment period changed - date:   
[ ] Notified measure adopted - date:  
[X] Notified measure published - date: 5 July 2022  
[X] Notified measure enters into force - date: 6 September 2022  
[X] Text of final measure available from1:  
https://www.govinfo.gov/content/pkg/FR -2022-07-05/html/2022 -13324.htm  
https://www.govinfo.gov/content/pkg/FR -2022-07-05/pdf/2022 -13324.pdf  
https://members.wto.org/crnattachments/2022/TBT/USA/final_measure/22_4533_00_
e.pdf 
[ ] Notified measure withdrawn or revoked - date:  
Relevant symbol if measure re -notified:   
[ ] Content or scope of notified measure changed  and text available from1:  
New deadline for comments (if applicable):   
[ ] Interpretive guidance issued and text available from1:  
[ ] Other:  
 
Description:  TITLE: Significant New Uses of Chemical Substances; Updates to the Hazard 
Communication Program and Regulatory Framework; Minor Amendments to Reporting Requirements 
for Premanufacture Notices  
AGENCY: Environmental Protection Agency (EPA)  
ACTION: Final rule  
SUMMARY: The Environmental Protection Agency (EPA) is amending the regulations governing 
significant new uses of chemical substances under the Toxic Su bstances Control Act (TSCA) to align 
with revisions that were made to the Occupational Safety and Health Administration (OSHA) Hazard 
 
1 This information can be provided by including a website address, a pdf attachment, or other 
information on where the text of the final /modified  measure and/or interpretive guidance can be obtained.  G/TBT/N/USA/1171/Add.2  
 
- 2 - 
 
  Communications Standard (HCS) and changes to the OSHA Respiratory Protection Standard and the 
National Institute for Occup ational Safety and Health (NIOSH) respirator certification requirements 
for the respiratory protection of workers from exposure to chemicals. In addition, EPA is amending 
the regulations governing Significant New Use Rules (SNURs) to address issues that ha ve been 
identified by EPA and raised by stakeholders through public comments. EPA is also making a minor 
change to reporting requirements for premanufacture notices (PMNs) and other TSCA notifications. 
EPA expects these changes to have minimal impact on th e costs and burdens of compliance, while 
updating the significant new use reporting requirements to assist in addressing any potential risks 
to human health and the environment.  
DATES: This final rule is effective 6 September 2022.  
This final rule and prev ious actions notified under the symbol G/TBT/N/USA/1171  are identified by 
Docket Number EPA -HQ-OPPT-2014-0650. The Docket Folder is available from Regulations.gov at 
https://www.regulations.gov/docket/EPA -HQ-OPPT-2014-0650/document  and provides access to 
primary and supporting documents as well as comments received. Documents are also accessi ble 
from Regulations.gov  by searching the Docket Number.  
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