G/SPS/N/CAN/1492  
13 March 2023  
(23-1828) Page: 1/2 
Committee on Sanitary and Phytosanitary Measures  Original: English/French  
 
  NOTIFICATION  
1. Notifying Member:  CANADA  
If applicable, name of local government involved:   
2. Agency responsible:  Health Canada  
3. Products covered (provide tariff item number(s) as specified in national 
schedules deposited with the WTO; ICS numbers should be provided in addition, 
where applicable):  Transglutaminase from Streptomyces mobaraensis  M2020197 in 
various foods (ICS code: 67.220.20)  
4. Regions or countries likely to be affected, to the extent relevant or practicable : 
[X] All trading partners   
[ ] Specific regions or countries:   
5. Title of the notified document:  Notice of Modification to the List of Permitted Food 
Enzymes  to Enable the Use of Transglutaminase from Streptomyces mobaraensis  
M2020197 in Vari ous Foods . Language(s):  English and French . Number of pages:  5 
and 6 
https://members.wto.org/crnattachments/2023/SPS/CAN/23_1882_00_e.pdf  
https://members.wto.org/crnattachments/2023/SPS/CAN/23_1882_00_f.pdf  
6. Description of content:  Health Canada's Food Directorate completed a premarket safety 
assessment of a food additive submission seeking authorization for the use of 
transglutaminase from Streptomyces mobaraensis  M2020197 in various foods.  
Transglutaminase from another source is already permitted for use in Canada in a number 
of the foods reque sted by the petitioner. Prior to this Notice, S. mobaraensis  M2020197 
was not a permitted source for any food enzyme in Canada.  
The results of the premarket assessment support the safety of transglutaminase from S. 
mobaraensis  M2020197 for its requested us es. Consequently, Health Canada has enabled 
the use of transglutaminase from this source as described in the information document by 
modifying the List of Permitted Food Enzymes , effective 2 March 2023.  
The purpose of this information document is to public ly announce the Department's 
decision in this regard and to provide the appropriate contact information for those wishing 
to submit an inquiry or new scientific information relevant to the safety of this food 
additive.  
7. Objective and rationale: [X]  food safety, [  ] animal health, [  ] plant protection, 
[ ] protect humans from animal/plant pest or disease, [  ] protect territory from 
other damage from pests.   
8. Is there a relevant international standard? If so, identify the standard:  
[ ] Codex Alimentarius Commission (e.g.  title or serial number of Codex 
standard or related text) :  G/SPS/N/CAN/1492  
 
- 2 - 
 
  [ ] World Organization for Animal Health (OIE) (e.g.  Terrestrial or Aquatic 
Animal Health Code, chapter number) :  
[ ] International Plant Protection Convention (e.g.  ISPM number) :  
[X] None  
Does this proposed regulation conform to the relevant international standard?  
[ ] Yes   [  ] No 
If no, describe, whenever possible, how and why it deviates from the 
international stand ard:  
9. Other relevant documents and language(s) in which these are available:  
Health  Canada's Food and Nutrition – 'Public Involvement and Partnerships' Website, 
posted 2 March 2023 (available in English and French):  
https://www.canada.ca/en/health -canada/services/food -nutrition/public -involvement -
partnerships.html  (English)  
https://www.canada.ca/fr/sante -canada/services/aliments -nutrition/participation -public -
partenariats.html  (French)  
10. Proposed date of adoption (dd/mm/yy) : 2 March 20 23 
Proposed date of publication (dd/mm/yy) :  
11. Proposed date of entry into force: [  ] Six months from date of publication , and/or  
(dd/mm/yy) : 2 March 2023  
[ ] Trade facilitating measure   
12. Final date for comments: [  ] Sixty days from the date of circulation of the 
notification and/or (dd/mm/yy) : 15 May 2023  
Agency or authority designated to handle comments: [  ] National Notification 
Authority, [X]  National Enquiry Point. Address, fax number and e -mail address (if 
availa ble) of other body:   
13. Text(s) available from: [  ] National Notification Authority, [X]  National Enquiry 
Point. Address, fax number and e -mail address (if available) of other body:   
The Notice of Modification to the List of Permitted Food Enzymes to Enable the Use of 
Transglutaminase from Streptomyces mobaraensis M2020197 in Various Foods  is available 
through the following weblink:  
https://www.canada.ca/en/health -canada/services/food -nutrition/public -involvement -
partnerships/notice -modification -list-permitted -food-enzymes -enable -use-
transglutaminase -streptomyces -mobaraensis -m2020197 -various -foods.html  (English)  
https://www.canada.ca/fr/sante -canada/services/aliments -nutrition/participation -public -
partenariats/avi s-liste-enzymes -alimentaires -autorisees -afin-permettre -utilisation -
transglutaminase -issue-streptomyces -mobaraensis -m2020197.html  (French)  
Canada's Notification Authority and Enquiry Point  
Technical Barriers and Regulations Division  
Global Affairs Canada  
111 Sussex Drive  
Ottawa, Ontario K1A 0G2  
Canada  
Tel: +(343) 203 4273  
Fax: +(613) 943 0346  
E-mail: enquirypoint@international.gc.ca