G/SPS/N/EU/590  
 
18 August 2022  
(22-6265) Page: 1/2 
Committee on Sanitary and Phytosanitary Measures  Original: English  
 
  NOTIFICATION  
1. Notifying Member:  EUROPEAN UNION  
If applicable, name of local government involved:   
2. Agency responsible:  European Commission, Health and Food Safety Directorate -General  
3. Products covered (provide tariff item number(s) as specified in national 
schedules deposited with the WTO; ICS numbers should be provided in addition, 
where applicable):  Ethoxyquin (6 -ethoxy -1,2-dihydro -2,2,4-trimethylquinoline) as a 
feed additive and all types of animal feed containing ethoxy quin 
4. Regions or countries likely to be affected, to the extent relevant or practicable : 
[X] All trading partners   
[ ] Specific regions or countries:   
5. Title of the notified document:  Commission Implementing Regulation (EU) 2022/1375 
of 5 August 2022  concerning the denial of authorisation of ethoxyquin as a feed additive 
belonging to the functional group of antioxidants and repealing Implementing Regulation 
(EU) 2017/962 (Text with EEA relevance) . Language(s):  English, French and Spanish . 
Number of pages:  3 
https://members.wto.org/crnattachments/2022/SPS/EEC/22_5659_00_e.pdf  
https://members.wto.org/crnattachments/2022/SPS/EEC/22_5659_00_f.pdf  
https://members.wto.org/crnattachments/2022/SPS/EEC/22_5659_00_s.pdf  
6. Description of content:  The authorisation of ethoxyquin used as an antioxidant feed 
additive for all animal species had been suspended by Commission Implementing 
Regulation (EU) 2017/962 of 7 June 2017, as amended by Commission Implementing 
Regulation (EU) 2021/412, on the basis of the opinion of the European Food Safety 
Authority (EFSA) of 2 1 October 2015 ( cf notification G/SPS/N/EU/190). The authorisation 
of the additive was suspended pending the submission and assessment of supplementary 
data to be produced by the applicant for authorisation, in accordance with a time schedule 
listing the n ecessary studies to be carried out. Implementing Regulation (EU) 2017/962 
provided for a review of the suspension measure by 31 December 2022 at the latest and in 
any event after the adoption by EFSA of a non -favourable opinion on the safety and 
efficacy o f the additive ethoxyquin.  
After assessment of the submitted supplementary data, EFSA adopted on 27 January 2022 
a new opinion, which was not favourable as regards the safety of the additive, in particular 
for long -living and reproductive animals, for cons umers and for the environment. 
Therefore, since the conditions for authorisation of the additive laid down by the relevant 
EU legislation are still not met, the authorisation of ethoxyquin had to be denied, which is 
the subject matter of Commission Impleme nting Regulation (EU) 2022/1375. The notified 
measure therefore confirms the withdrawal from the EU market of the feed additive 
ethoxyquin for use for all animal species.  G/SPS/N/EU/590  
 
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  7. Objective and rationale: [X]  food safety, [X]  animal health, [  ] plant protection , 
[ ] protect humans from animal/plant pest or disease, [  ] protect territory from 
other damage from pests.   
8. Is there a relevant international standard? If so, identify the standard:  
[X] Codex Alimentarius Commission (e.g.  title or serial number of Codex 
standard or related text) : Code of practice on Good Animal Feeding 
CAC/RCP  54-2004 
[ ] World Organization for Animal Health (OIE) (e.g.  Terrestrial or Aquatic 
Animal Health Code, chapter number) :  
[ ] International Plant Protection Convention (e.g.  ISPM number) :  
[ ] None  
Does this proposed regulation conform to the relevant international standard?  
[X] Yes   [  ] No 
If no, describe, whenever possible, how and why it deviates from the 
international stand ard:  
9. Other relevant documents and language(s) in which these are available:  
Opinion  of EFSA of 27 January 2022, published in the EFSA Journal 2022;20(3):7166  
(available in English)  
10. Proposed date of adoption (dd/mm/yy) : 5 August 2022  
Proposed date of publication (dd/mm/yy) : 8 August 2022  
11. Proposed date of entry into force: [  ] Six months from date of publication , and/or  
(dd/mm/yy) : 28 August 2022 . Commission Implementing Regulation (EU) 2022/1375 
enters into force on the twentieth day following its publication in the Official Journal of the 
European Union.  
[ ] Trade facilitating measure   
12. Final date for comments: [  ] Sixty days from the date of circulation of the 
notification and/or (dd/mm/yy) : Not applicable  
Agency or authority designated to handle comments: [X]  National Notification 
Authority, [X]  National Enquiry Point. Address, fax number and e -mail address (if 
available) of other body:   
European Commission  
DG Health and Food Safety, Unit D2 -Multilateral International Relations  
Rue Froissart 101  
B-1049 Brussels  
Tel: +(32 2) 29 54263  
Fax: +(32 2) 29 98090  
E-mail: sps@ec.europa.eu  
13. Text(s) available from: [X]  National Notification Authority, [X]  National Enquiry 
Point. Address, fax number and e -mail address (if available) of other body:   
European Commission  
DG Health and Foo d Safety, Unit D2 -Multilateral International Relations  
Rue Froissart 101  
B-1049 Brussels  
Tel: +(32 2) 29 54263  
Fax: +(32 2) 29 98090  
E-mail: sps@ec.europa.eu