<table><caption>Table III. Continued</caption><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td></td><td></td><td>BPD, D3, LUS score + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D7, LUS score + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D7, LUS score + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Baud<sup>58</sup></td><td>2021</td><td>Death/BPD, at birth, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, at birth, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Dai<sup>59</sup></td><td>2021</td><td>Death/BPD, unclear, genetics + clinical data</td><td>+</td><td>?</td><td>+</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>?</td></tr><tr><td></td><td></td><td>Death/BPD, unclear, clinical data</td><td>+</td><td>?</td><td>+</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>?</td></tr><tr><td></td><td></td><td>Death/BPD, unclear, genetics + clinical data</td><td>+</td><td>?</td><td>+</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>?</td></tr><tr><td>Gerull<sup>60</sup></td><td>2021</td><td>Death/BPD, D7, blood biomarkers + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, blood biomarkers + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, blood biomarkers + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Khurshid<sup>61</sup></td><td>2021</td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr></tbody><tfoot><tr><td colspan="12" style="text-align: right;">(continued)</td></tr></tfoot></table>
<table><caption>Table III. Continued</caption><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="3">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td></td><td></td><td>BPD, D3, LUS score + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D7, LUS score + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D7, LUS score + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Baud<sup>58</sup></td><td>2021</td><td>Death/BPD, at birth, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, at birth, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Dai<sup>59</sup></td><td>2021</td><td>Death/BPD, unclear, genetics + clinical data</td><td>+</td><td>?</td><td>+</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>?</td></tr><tr><td></td><td></td><td>Death/BPD, unclear, clinical data</td><td>+</td><td>?</td><td>+</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>?</td></tr><tr><td></td><td></td><td>Death/BPD, unclear, genetics + clinical data</td><td>+</td><td>?</td><td>+</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>?</td></tr><tr><td>Gerull<sup>60</sup></td><td>2021</td><td>Death/BPD, D7, blood biomarkers + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, blood biomarkers + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, blood biomarkers + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Khurshid<sup>61</sup></td><td>2021</td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr></tbody><tfoot><tr><td colspan="12" style="text-align: right;">(continued)</td></tr></tfoot></table>
<figure><img src="image_22.png" /><figcaption>Table III. Continued</figcaption></figure>

<table><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr></tbody></table>

(continued)
<figure><img src="image_22.png" /><figcaption>Table III. Continued</figcaption></figure>

<table><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr></tbody></table>

(continued)
<figure><img src="image_23.png" /><figcaption>Table III. Continued</figcaption></figure>

<table><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td rowspan="6">Mohamed<sup>63</sup></td><td rowspan="6">2021</td><td>BPD, D3, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D3, LUS score + clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, LUS score + clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D14, LUS score + clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Shim<sup>64</sup></td><td rowspan="2">2021</td><td>BP D0, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BP D0, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Song<sup>65</sup></td><td rowspan="2">2021</td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>?</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, blood biomarkers + clinical data</td><td>+</td><td>+</td><td>+</td><td>?</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Soullane<sup>66</sup></td><td>2021</td><td>BPD, D10, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Ushida<sup>67</sup></td><td rowspan="2">2021</td><td>BPD, D0, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D1, LUS score + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Woods<sup>68</sup></td><td rowspan="2">2021</td><td>Death/BPD, D3, LUS score + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, LUS score + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="4">Zhang<sup>69</sup></td><td rowspan="4">2021</td><td>BPD, D3, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D14, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Sharma<sup>54</sup></td><td rowspan="2">2020</td><td>BPD, D14, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>?</td><td>?</td><td>+</td><td>●</td><td>?</td></tr><tr><td rowspan="2">Alvarez-Fuente<sup>51</sup></td><td rowspan="2">2019</td><td>BPD, D7, echocardiographic data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>?</td><td>?</td><td>+</td><td>●</td><td>?</td></tr><tr><td>BPD, D7, echocardiographic data + blood biomarkers</td><td>+</td><td>+</td><td>+</td><td>●</td><td>?</td><td>?</td><td>+</td><td>●</td><td>?</td></tr></tbody></table>

(continued)
<figure><img src="image_23.png" /><figcaption>Table III. Continued</figcaption></figure>

<table><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td rowspan="6">Mohamed<sup>63</sup></td><td rowspan="6">2021</td><td>BPD, D3, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D14, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D3, LUS score + clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, LUS score + clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D14, LUS score + clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Shim<sup>64</sup></td><td rowspan="2">2021</td><td>BP D0, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BP D0, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Song<sup>65</sup></td><td rowspan="2">2021</td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>?</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, blood biomarkers + clinical data</td><td>+</td><td>+</td><td>+</td><td>?</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Soullane<sup>66</sup></td><td>2021</td><td>BPD, D10, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Ushida<sup>67</sup></td><td>2021</td><td>BPD, D0, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="3">Woods<sup>68</sup></td><td rowspan="3">2021</td><td>Death/BPD, D1, LUS score + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D3, LUS score + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, LUS score + clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="3">Zhang<sup>69</sup></td><td rowspan="3">2021</td><td>BPD, D3, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D14, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Sharma<sup>54</sup></td><td>2020</td><td>BPD, D14, clinical data</td><td>+</td><td>●</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td></tr><tr><td rowspan="2">Alvarez-Fuente<sup>51</sup></td><td rowspan="2">2019</td><td>BPD, D7, echocardiographic data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>?</td><td>?</td><td>+</td><td>●</td><td>?</td></tr><tr><td>BPD, D7, echocardiographic data + blood biomarkers</td><td>+</td><td>+</td><td>+</td><td>●</td><td>?</td><td>?</td><td>+</td><td>●</td><td>?</td></tr></tbody></table>

(continued)
<table><caption>Table III. Continued</caption><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td rowspan="3">Beltempo<sup>50</sup></td><td rowspan="3">2019</td><td>BPD, H12, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, H12, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, H12, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Fairchild<sup>49</sup></td><td rowspan="2">2019</td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, clinical + monitoring data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="10">Valenzuela-Stutman<sup>46</sup></td><td rowspan="10">2019</td><td>BPD, D1, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D3, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D3, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D14, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Veneroni<sup>45</sup></td><td>2019</td><td>BPD, D1, lung mechanics</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Bentsen<sup>44</sup></td><td>2018</td><td>BPD, D2, ventilator data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Boghossian<sup>43</sup></td><td rowspan="2">2018</td><td>BPD, at birth, clinical data</td><td>+</td><td>+</td><td>●</td><td>●</td><td>?</td><td>?</td><td>●</td><td>●</td></tr><tr><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>●</td><td>●</td><td>?</td><td>?</td><td>●</td><td>●</td></tr><tr><td rowspan="2">Sullivan<sup>41</sup></td><td rowspan="2">2018</td><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>BPD, D7, monitoring data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td rowspan="3">Kandasamy<sup>40</sup></td><td rowspan="3">2017</td><td>BPD, D7, clinical + monitoring data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Death/BPD, unclear, cord blood biomarkers</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, unclear, cord blood biomarkers</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td></tr></tbody><tfoot><tr><td colspan="12" style="text-align: right;">(continued)</td></tr></tfoot></table>
<table><caption>Table III. Continued</caption><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td rowspan="3">Beltempo<sup>50</sup></td><td rowspan="3">2019</td><td>BPD, H12, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, H12, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, H12, clinical data</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Fairchild<sup>49</sup></td><td rowspan="2">2019</td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, clinical + monitoring data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="10">Valenzuela-Stutman<sup>46</sup></td><td rowspan="10">2019</td><td>BPD, D1, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D3, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D3, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D14, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Veneroni<sup>45</sup></td><td>2019</td><td>BPD, D1, lung mechanics</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Bentsen<sup>44</sup></td><td>2018</td><td>BPD, D2, ventilator data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Boghossian<sup>43</sup></td><td rowspan="2">2018</td><td>BPD, at birth, clinical data</td><td>+</td><td>+</td><td>●</td><td>●</td><td>?</td><td>?</td><td>●</td><td>●</td></tr><tr><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>●</td><td>●</td><td>?</td><td>?</td><td>●</td><td>●</td></tr><tr><td rowspan="2">Sullivan<sup>41</sup></td><td rowspan="2">2018</td><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>BPD, D7, monitoring data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td rowspan="3">Kandasamy<sup>40</sup></td><td rowspan="3">2017</td><td>BPD, D7, clinical + monitoring data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Death/BPD, unclear, cord blood biomarkers</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, unclear, cord blood biomarkers</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td></tr></tbody><tfoot><tr><td colspan="12" style="text-align: right;">(continued)</td></tr></tfoot></table>
<figure><img src="image_24.png" /><figcaption>Table III. Continued</figcaption></figure>

<table><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description (outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td>Wai<sup>37</sup></td><td>2016</td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>?</td><td>+</td><td>●</td><td>●</td></tr><tr><td>El-Khuffash<sup>36</sup></td><td>2015</td><td>Death/BPD, D2, echocardiographic data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>?</td><td>+</td><td>●</td><td>?</td></tr><tr><td>Kandasamy<sup>35</sup></td><td>2015</td><td>Death/BPD, D1, cord blood biomarkers</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Popova<sup>34</sup></td><td>2015</td><td>Death/BPD, unclear, tracheal biomarkers</td><td>?</td><td>?</td><td>+</td><td>●</td><td>●</td><td>?</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Schneibel<sup>32</sup></td><td>2013</td><td>BPD, D1, tracheal biomarkers</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>?</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Ambalavanan<sup>30</sup></td><td>2011</td><td>Death/BPD, D7, clinical data</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Laughon<sup>28</sup></td><td>2011</td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D3, clinical data</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Messershmidt<sup>27</sup></td><td>2011</td><td>BPD, D1, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Subramanian<sup>26</sup></td><td>2011</td><td>BPD, D6, clinical data</td><td>+</td><td>?</td><td>+</td><td>●</td><td>+</td><td>?</td><td>+</td><td>●</td><td>?</td></tr><tr><td>Ambalavanan<sup>25</sup></td><td>2008</td><td>Death/BPD, unclear, clinical data</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>Death/BPD, unclear, clinical data</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Choi<sup>23</sup></td><td>2006</td><td>BPD, unclear, tracheal biomarkers</td><td>+</td><td>●</td><td>+</td><td>●</td><td>●</td><td>?</td><td>●</td><td>●</td><td>●</td></tr><tr><td>Henderson-Smart<sup>22</sup></td><td>2006</td><td>BPD, at birth, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Kim<sup>21</sup></td><td>2005</td><td>BPD, D4, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D10, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Ng<sup>19</sup></td><td>2004</td><td>Death/BPD, D14, blood biomarkers</td><td>+</td><td>●</td><td>+</td><td>●</td><td>●</td><td>●</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Chien<sup>18</sup></td><td>2002</td><td>BPD, H12, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, H12, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr></tbody></table>

(continued)
<table><caption>Table III. Continued</caption><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description (outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td>Wai<sup>37</sup></td><td>2016</td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>?</td><td>+</td><td>●</td><td>●</td></tr><tr><td>El-Khuffash<sup>36</sup></td><td>2015</td><td>Death/BPD, D2, echocardiographic data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>?</td><td>+</td><td>●</td><td>?</td></tr><tr><td>Kandasamy<sup>35</sup></td><td>2015</td><td>Death/BPD, D1, cord blood biomarkers</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Popova<sup>34</sup></td><td>2015</td><td>Death/BPD, unclear, tracheal biomarkers</td><td>?</td><td>?</td><td>+</td><td>●</td><td>●</td><td>?</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Schneibel<sup>32</sup></td><td>2013</td><td>BPD, D1, tracheal biomarkers</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>?</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Ambalavanan<sup>30</sup></td><td>2011</td><td>Death/BPD, D7, clinical data</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Laughon<sup>28</sup></td><td>2011</td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D3, clinical data</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D7, clinical data</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, D14, clinical data</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Messershmidt<sup>27</sup></td><td>2011</td><td>BPD, D1, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Subramanian<sup>26</sup></td><td>2011</td><td>BPD, D6, clinical data</td><td>+</td><td>?</td><td>+</td><td>●</td><td>+</td><td>?</td><td>+</td><td>●</td><td>?</td></tr><tr><td>Ambalavanan<sup>25</sup></td><td>2008</td><td>Death/BPD, unclear, clinical data</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>Death/BPD, unclear, clinical data</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Choi<sup>23</sup></td><td>2006</td><td>BPD, unclear, tracheal biomarkers</td><td>+</td><td>●</td><td>+</td><td>●</td><td>●</td><td>?</td><td>●</td><td>●</td><td>●</td></tr><tr><td>Henderson-Smart<sup>22</sup></td><td>2006</td><td>BPD, at birth, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Kim<sup>21</sup></td><td>2005</td><td>BPD, D4, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D10, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Ng<sup>19</sup></td><td>2004</td><td>Death/BPD, D14, blood biomarkers</td><td>+</td><td>●</td><td>+</td><td>●</td><td>●</td><td>●</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Chien<sup>18</sup></td><td>2002</td><td>BPD, H12, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, H12, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr></tbody></table>

(continued)
<table><caption>Table III. Continued</caption><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td rowspan="2">Lui<sup>17</sup></td><td rowspan="2">2000</td><td>BPD, unclear, lung mechanics</td><td>+</td><td>+</td><td>+</td><td>●</td><td>-</td><td>?</td><td>+</td><td>●</td><td>●</td></tr><tr><td>BPD, unclear, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>-</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td rowspan="2">Yoder<sup>16</sup></td><td rowspan="2">1999</td><td>Death/BPD, H12, clinical data</td><td>-</td><td>+</td><td>+</td><td>●</td><td>-</td><td>+</td><td>●</td><td>-</td><td>●</td></tr><tr><td>Death/BPD, D3, clinical data</td><td>-</td><td>+</td><td>+</td><td>●</td><td>-</td><td>+</td><td>●</td><td>-</td><td>●</td></tr><tr><td rowspan="2">Subhedar<sup>14</sup></td><td rowspan="2">1998</td><td>Death/BPD, D1, echocardiographic data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>-</td><td>+</td><td>+</td><td>-</td><td>●</td></tr><tr><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>-</td><td>+</td><td>+</td><td>-</td><td>●</td></tr><tr><td>Ryan<sup>13</sup></td><td>1996</td><td>BPD, D4, clinical data</td><td>+</td><td>?</td><td>●</td><td>●</td><td>-</td><td>?</td><td>●</td><td>-</td><td>●</td></tr><tr><td colspan="12">Validated models</td></tr><tr><td rowspan="5">Alonso-Ojembarrena<sup>71</sup></td><td rowspan="5">2022</td><td>BPD, D1, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D3, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D7, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D14, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D7, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td rowspan="4">Aldecoa-Bilbao<sup>57</sup></td><td rowspan="4">2021</td><td>BPD, D7, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D3, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D3, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D7, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td rowspan="4">Alonso-Ojembarrena<sup>52</sup></td><td rowspan="4">2021</td><td>BPD, D7, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D14, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D14, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D7, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td rowspan="2">Baud<sup>58</sup></td><td rowspan="2">2021</td><td>Death/BPD, at birth, NICHD model</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>+</td><td>+</td></tr><tr><td>BPD, D3, RSS</td><td>+</td><td>+</td><td>?</td><td>●</td><td>-</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>Bhattacharjee<sup>56</sup></td><td>2021</td><td>BPD, D3, RSS</td><td>+</td><td>+</td><td>+</td><td>●</td><td>-</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>Gerull<sup>60</sup></td><td>2021</td><td>Death/BPD, D7, NICHD model</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>Liu<sup>62</sup></td><td>2021</td><td>BPD, D1, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr></tbody><tfoot><tr><td colspan="12">(continued)</td></tr></tfoot></table>
<table><caption>Table III. Continued</caption><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td rowspan="2">Lui<sup>17</sup></td><td rowspan="2">2000</td><td>BPD, unclear, lung mechanics</td><td>+</td><td>+</td><td>+</td><td>●</td><td>-</td><td>?</td><td>+</td><td>●</td><td>●</td></tr><tr><td>BPD, unclear, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>-</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td rowspan="2">Yoder<sup>16</sup></td><td rowspan="2">1999</td><td>Death/BPD, H12, clinical data</td><td>-</td><td>+</td><td>+</td><td>●</td><td>-</td><td>+</td><td>●</td><td>-</td><td>●</td></tr><tr><td>Death/BPD, D3, clinical data</td><td>-</td><td>+</td><td>+</td><td>●</td><td>-</td><td>+</td><td>●</td><td>-</td><td>●</td></tr><tr><td rowspan="2">Subhedar<sup>14</sup></td><td rowspan="2">1998</td><td>Death/BPD, D1, echocardiographic data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>-</td><td>+</td><td>+</td><td>-</td><td>●</td></tr><tr><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>-</td><td>+</td><td>+</td><td>-</td><td>●</td></tr><tr><td>Ryan<sup>13</sup></td><td>1996</td><td>BPD, D4, clinical data</td><td>+</td><td>?</td><td>●</td><td>●</td><td>-</td><td>?</td><td>●</td><td>-</td><td>●</td></tr><tr><td colspan="12">Validated models</td></tr><tr><td rowspan="5">Alonso-Ojembarrena<sup>71</sup></td><td rowspan="5">2022</td><td>BPD, D1, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D3, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D7, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D14, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D7, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td rowspan="4">Aldecoa-Bilbao<sup>57</sup></td><td rowspan="4">2021</td><td>BPD, D7, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D3, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D3, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D7, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td rowspan="4">Alonso-Ojembarrena<sup>52</sup></td><td rowspan="4">2021</td><td>BPD, D7, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D14, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>BPD, D14, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>Death/BPD, at birth, NICHD model</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>+</td><td>+</td></tr><tr><td>Bhattacharjee<sup>56</sup></td><td>2021</td><td>BPD, D3, RSS</td><td>+</td><td>+</td><td>?</td><td>●</td><td>-</td><td>+</td><td>+</td><td>-</td><td>●</td></tr><tr><td>Gerull<sup>60</sup></td><td>2021</td><td>Death/BPD, D7, NICHD model</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr><tr><td>Liu<sup>62</sup></td><td>2021</td><td>BPD, D1, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>-</td><td>+</td></tr></tbody><tfoot><tr><td colspan="12">(continued)</td></tr></tfoot></table>
<figure><img src="image_25.png" /><figcaption>Table III. Continued</figcaption></figure>

<table><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="3">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td></td><td></td><td>BPD, D2, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D3, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D6, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D9, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D12, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D1, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D2, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D3, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D6, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D9, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D12, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D1, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D2, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D3, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D6, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D9, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D12, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Mohamed<sup>63</sup></td><td>2021</td><td>BPD, D3, LUS score</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>?</td></tr><tr><td></td><td></td><td>BPD, D7, LUS score</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>?</td></tr><tr><td></td><td></td><td>BPD, D14, LUS score</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>?</td></tr><tr><td>Shim<sup>64</sup></td><td>2021</td><td>BPD, D0, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D0, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr></tbody></table>

(continued)
<figure><img src="image_24.png" /><figcaption>Table III. Continued</figcaption></figure>

<table><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="3">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td></td><td></td><td>BPD, D2, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D3, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D6, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D9, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D12, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D1, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D2, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D3, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D6, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D9, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D12, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D1, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D2, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D3, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D6, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D9, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D12, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Mohamed<sup>63</sup></td><td>2021</td><td>BPD, D3, LUS score</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>?</td></tr><tr><td></td><td></td><td>BPD, D7, LUS score</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>?</td></tr><tr><td></td><td></td><td>BPD, D14, LUS score</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>?</td></tr><tr><td>Shim<sup>64</sup></td><td>2021</td><td>BPD, D0, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D0, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr></tbody></table>

(continued)
<table><caption>Table III. Continued</caption><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td>Ushida<sup>67</sup></td><td>2021</td><td>BPD, D0, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="7">Woods<sup>68</sup></td><td rowspan="7">2021</td><td>BPD, D1, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D3, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D1, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D3, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Bhattacharjee<sup>56</sup></td><td>2020</td><td>BPD, unclear, RSS score</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>●</td></tr><tr><td>Oulego-Erroz<sup>55</sup></td><td>2020</td><td>BPD, D7, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td rowspan="4">Sotodate<sup>53</sup></td><td rowspan="4">2020</td><td>BPD, H1, CRIB score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, D1, SNAP-II score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, H12, SNAP-II score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, D14, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td rowspan="4">Alonso-Ojembarrena<sup>52</sup></td><td rowspan="4">2019</td><td>BPD, D1, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, D3, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, D14, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Beltempo<sup>50</sup></td><td rowspan="2">2019</td><td>BPD, H12, SNAP-II score</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, H12, SNAP-II score</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>Jung<sup>48</sup></td><td>2019</td><td>Death/BPD, D7, RSS score</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>●</td></tr><tr><td rowspan="2">Lee<sup>47</sup></td><td rowspan="2">2019</td><td>BPD, H1, CRIB-II score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, H1, CRIB-II score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr></tbody><tfoot><tr><td colspan="12" style="text-align: right;">(continued)</td></tr></tfoot></table>
<table><caption>Table III. Continued</caption><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description (outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td>Ushida<sup>67</sup></td><td>2021</td><td>BPD, D0, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="7">Woods<sup>68</sup></td><td rowspan="7">2021</td><td>BPD, D1, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D3, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D1, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D3, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, modified LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Bhattacharjee<sup>56</sup></td><td>2020</td><td>BPD, unclear, RSS score</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>●</td></tr><tr><td>Oulego-Erroz<sup>55</sup></td><td>2020</td><td>BPD, D7, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td rowspan="4">Sotodate<sup>53</sup></td><td rowspan="4">2020</td><td>BPD, H1, CRIB score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, D1, SNAP-II score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, H12, SNAP-II score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, D14, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td rowspan="4">Alonso-Ojembarrena<sup>52</sup></td><td rowspan="4">2019</td><td>BPD, D1, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, D3, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, D14, LUS score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Beltempo<sup>50</sup></td><td rowspan="2">2019</td><td>BPD, H12, SNAP-II score</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, H12, SNAP-II score</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>Jung<sup>48</sup></td><td>2019</td><td>Death/BPD, D7, RSS score</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>●</td></tr><tr><td rowspan="2">Lee<sup>47</sup></td><td rowspan="2">2019</td><td>BPD, H1, CRIB-II score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr><tr><td>BPD, H1, CRIB-II score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td></tr></tbody><tfoot><tr><td colspan="12" style="text-align: right;">(continued)</td></tr></tfoot></table>
<figure><img src="image_26.png" /><figcaption>Table III. Continued</figcaption></figure>

<table><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td rowspan="2">Gulliver<sup>42</sup></td><td rowspan="2">2018</td><td>Death/BPD, D7, NICHD model</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td></tr><tr><td>Death/BPD, D14, NICHD model</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td></tr><tr><td>Özcan<sup>39</sup></td><td>2017</td><td>BPD, H12, SNAP-II score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="4">Sullivan<sup>38</sup></td><td rowspan="4">2016</td><td>BPD, D1, monitoring data</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, monitoring data</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, H12, SNAP-II score</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, H12, CRIB-II score</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Truog<sup>33</sup></td><td rowspan="2">2014</td><td>Death/BPD, D7, NICHD model</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D14, NICHD model</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Sehgal<sup>31</sup></td><td>2013</td><td>BPD, unclear, echocardiographic data</td><td>●</td><td>●</td><td>+</td><td>●</td><td>●</td><td>?</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Ambalavanan<sup>30</sup></td><td>2011</td><td>Death/BPD, D7, clinical data</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Carvalho<sup>29</sup></td><td>2011</td><td>BPD, H12, SNAP-II score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td rowspan="9">Laughon<sup>28</sup></td><td rowspan="9">2011</td><td>Death/BPD, D1, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D1, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D3, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D3, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D14, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D14, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>May<sup>24</sup></td><td>2007</td><td>BPD, D2, Madan score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr></tbody></table>

(continued)
<figure><img src="image_25.png" /><figcaption>Table III. Continued</figcaption></figure>

<table><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description (outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td rowspan="2">Gulliver<sup>42</sup></td><td rowspan="2">2018</td><td>Death/BPD, D7, NICHD model</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td></tr><tr><td>Death/BPD, D14, NICHD model</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>?</td><td>●</td><td>?</td></tr><tr><td>Özcan<sup>39</sup></td><td>2017</td><td>BPD, H12, SNAP-II score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="4">Sullivan<sup>38</sup></td><td rowspan="4">2016</td><td>BPD, D1, monitoring data</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, D7, monitoring data</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, H12, SNAP-II score</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>BPD, H12, CRIB-II score</td><td>●</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td rowspan="2">Truog<sup>33</sup></td><td rowspan="2">2014</td><td>Death/BPD, D7, NICHD model</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D14, NICHD model</td><td>+</td><td>+</td><td>?</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Sehgal<sup>31</sup></td><td>2013</td><td>BPD, unclear, echocardiographic data</td><td>●</td><td>●</td><td>+</td><td>●</td><td>●</td><td>?</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Ambalavanan<sup>30</sup></td><td>2011</td><td>Death/BPD, D7, clinical data</td><td>?</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Carvalho<sup>29</sup></td><td>2011</td><td>BPD, H12, SNAP-II score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td rowspan="8">Laughon<sup>28</sup></td><td rowspan="8">2011</td><td>Death/BPD, D1, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D1, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D3, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D3, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D7, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D14, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Death/BPD, D14, NICHD model</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>May<sup>24</sup></td><td>2007</td><td>BPD, D2, Madan score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr></tbody></table>

(continued)
<figure><img src="image_27.png" /></figure>

<table><caption>Table III. Continued</caption><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td></td><td></td><td>BPD, D2, Madan score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>BPD, D7, Madan score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>BPD, D7, Madan score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Henderson-Smart<sup>22</sup></td><td>2006</td><td>BPD, at birth, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Kim<sup>21</sup></td><td>2005</td><td>BPD, D4, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D10, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D4, Yoder score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D7, Yoder score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D10, Yoder score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Greenough<sup>20</sup></td><td>2004</td><td>BPD, D7, Chest radiograph score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>BPD, D7, Chest radiograph score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Chien<sup>18</sup></td><td>2002</td><td>BPD, H12, SNAP score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>BPD, H12, SNAP-II score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Yoder<sup>16</sup></td><td>1999</td><td>Death/BPD, H12, Yoder score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>Death/BPD, D3, Yoder score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>Death/BPD, H12, Sinkin score</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>Death/BPD, D3, Ryan score</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Hentschel<sup>15</sup></td><td>1998</td><td>BPD, H12, Sinkin score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>Death/BPD, H12, Sinkin score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>BPD, D10, Sinkin score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>Death/BPD, D10, Sinkin score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr></tbody><tfoot><tr><td colspan="12" style="text-align: right;">(continued)</td></tr></tfoot></table>
<figure><img src="image_26.png" /></figure>

<table><caption>Table III. Continued</caption><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="4">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td></td><td></td><td>BPD, D2, Madan score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>BPD, D7, Madan score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>BPD, D7, Madan score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Henderson-Smart<sup>22</sup></td><td>2006</td><td>BPD, at birth, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Kim<sup>21</sup></td><td>2005</td><td>BPD, D4, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D7, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D10, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D4, Yoder score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D7, Yoder score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, D10, Yoder score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Greenough<sup>20</sup></td><td>2004</td><td>BPD, D7, Chest radiograph score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>BPD, D7, Chest radiograph score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Chien<sup>18</sup></td><td>2002</td><td>BPD, H12, SNAP score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>BPD, H12, SNAP-II score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Yoder<sup>16</sup></td><td>1999</td><td>Death/BPD, H12, Yoder score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>Death/BPD, D3, Yoder score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>?</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>Death/BPD, H12, Sinkin score</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>Death/BPD, D3, Ryan score</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Hentschel<sup>15</sup></td><td>1998</td><td>BPD, H12, Sinkin score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>Death/BPD, H12, Sinkin score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>BPD, D10, Sinkin score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>Death/BPD, D10, Sinkin score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr></tbody><tfoot><tr><td colspan="12" style="text-align: right;">(continued)</td></tr></tfoot></table>
<figure><img src="image_28.png" /><figcaption>Table III. Continued</figcaption></figure>

<table><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="3">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td></td><td></td><td>BPD, H12, CRIB score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, H12, CRIB score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, at admission, Berlin score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, at admission, Berlin score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Subhedar<sup>14</sup></td><td>1998</td><td>Death/BPD, D1, echocardiographic data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Ryan<sup>13</sup></td><td>1996</td><td>BPD, D4, clinical data</td><td>?</td><td>?</td><td>●</td><td>●</td><td>?</td><td>?</td><td>●</td><td>●</td><td>●</td></tr></tbody></table>

BP, blood pressure; CRIB, Clinical Risk Index for Babies; LUS, lung ultrasound; NICHD, Eunice Kennedy Shriver National Institute of Child Health and Human Development; RoB, risk of bias; SNAP, Score for Neonatal Acute Physiology; SNAPPE, Score for Neonatal Acute Physiology Perinatal Extension.

<figure><img src="image_29.png" /></figure>

= low ROB/low concern regarding applicability/

<figure><img src="image_30.png" /></figure>

= high ROB/high concern regarding applicability/

<figure><img src="image_31.png" /></figure>

= unclear ROB/unclear concern regarding applicability.
<figure><img src="image_27.png" /><figcaption>Table III. Continued</figcaption></figure>

<table><thead><tr><th rowspan="2">Study</th><th rowspan="2">Year</th><th rowspan="2">Model description<br>(outcome, timing, type of predictors)</th><th colspan="4">RoB</th><th colspan="3">Applicability</th><th colspan="2">Overall</th></tr><tr><th>Participants</th><th>Predictors</th><th>Outcome</th><th>Analysis</th><th>Participants</th><th>Predictors</th><th>Outcome</th><th>RoB</th><th>Applicability</th></tr></thead><tbody><tr><td></td><td></td><td>BPD, H12, CRIB score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, H12, CRIB score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>BPD, at admission, Berlin score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td></td><td></td><td>Death/BPD, at admission, Berlin score</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td><td>+</td><td>+</td><td>●</td><td>+</td></tr><tr><td>Subhedar<sup>14</sup></td><td>1998</td><td>Death/BPD, D1, echocardiographic data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td></td><td></td><td>Death/BPD, D1, clinical data</td><td>+</td><td>+</td><td>+</td><td>●</td><td>●</td><td>+</td><td>+</td><td>●</td><td>●</td></tr><tr><td>Ryan<sup>13</sup></td><td>1996</td><td>BPD, D4, clinical data</td><td>?</td><td>?</td><td>●</td><td>●</td><td>?</td><td>?</td><td>●</td><td>●</td><td>●</td></tr></tbody></table>

BP, blood pressure; CRIB, Clinical Risk Index for Babies; LUS, lung ultrasound; NICHD, Eunice Kennedy Shriver National Institute of Child Health and Human Development; RoB, risk of bias; SNAP, Score for Neonatal Acute Physiology; SNAPPE, Score for Neonatal Acute Physiology Perinatal Extension.

+ = low ROB/low concern regarding applicability/ - = high ROB/high concern regarding applicability/ ? = unclear ROB/unclear concern regarding applicability.