# ATF1 wt Allele

National Cancer Institute

## Source

National Cancer Institute. <u>ATF1 wt Allele</u>. NCI Thesaurus. Code C92178.

Human ATF1 wild-type allele is located in the vicinity of 12q13 and is approximately 57 kb in length. This allele, which encodes cyclic AMP-dependent transcription factor ATF-1 protein, plays a role in transcriptional regulation. Two translocations of this gene are associated with angiomatoid fibrous histiocytoma and clear cell sarcoma. Translocation t(12;16)(q13;p11.2) with the FUS gene and t(12;22)(q13;q12) with the EWSR1 gene are expressed as fusion proteins.