# Corrigendum: Current phenotypic and genetic spectrum of syndromic deafness in Tunisia: paving the way for precision auditory health

Rahma Mkaouar, Zied Riahi, Jihene Marrakchi, Nessrine Mezzi, Lilia Romdhane, Maroua Boujemaa, Hamza Dallali, Marwa Sayeb, Saida Lahbib, Hager Jaouadi, et al.

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► To cite this version:

Rahma Mkaouar, Zied Riahi, Jihene Marrakchi, Nessrine Mezzi, Lilia Romdhane, et al. Corrigendum: Current phenotypic and genetic spectrum of syndromic deafness in Tunisia: paving the way for precision auditory health. Frontiers in Genetics, 2024, 15, pp.1437233. 10.3389/fgene.2024.1437233. pasteur-04691609

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EDITED AND REVIEWED BY
Ferran Casals,
University of Barcelona, Spain

*CORRESPONDENCE
Rahma Mkaouar,
 rahma.mkaouar@fst.utm.tn

RECEIVED 23 May 2024

ACCEPTED 27 May 2024

PUBLISHED 25 June 2024

CITATION

Mkaouar R, Riahi Z, Marrakchi J, Mezzi N, Romdhane L, Boujemaa M, Dallali H, Sayeb M, Lahbib S, Jaouadi H, Boudabbous H, Zekri L, Chargui M, Messaoud O, Elyounsi M, Kraoua I, Zaouak A, Turki I, Mokni M, Boucher S, Petit C, Giraudet F, Mbarek C, Besbes G, Halayem S, Zainine R, Turki H, Tounsi A, Bonnet CRYSTEL, Mrad R, Abdelhak S, Trabelsi M and Charfeddine C (2024), Corrigendum: Current phenotypic and genetic spectrum of syndromic deafness in Tunisia: paving the way for precision auditory health.

Front. Genet. 15:1437233.

doi: 10.3389/fgene.2024.1437233

COPYRIGHT

© 2024 Mkaouar, Riahi, Marrakchi, Mezzi, Romdhane, Boujemaa, Dallali, Sayeb, Lahbib, Jaouadi, Boudabbous, Zekri, Chargui, Messaoud, Elyounsi, Kraoua, Zaouak, Turki, Mokni, Boucher, Petit, Giraudet, Mbarek, Besbes, Halayem, Zainine, Turki, Tounsi, Bonnet, Mrad, Abdelhak, Trabelsi and Charfeddine. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

# Corrigendum: Current phenotypic and genetic spectrum of syndromic deafness in Tunisia: paving the way for precision auditory health

Rahma Mkaouar¹*, Zied Riahi¹, Jihene Marrakchi¹,²,
Nessrine Mezzi¹,³, Lilia Romdhane¹,⁴, Maroua Boujemaa¹,
Hamza Dallali¹, Marwa Sayeb¹, Saida Lahbib¹, Hajer Jaouadi¹,⁵,
Hela Boudabbous⁶,⁷,⁸, Lotfi Zekri¹,⁹, Mariem Chargui¹,
Olfa Messaoud¹, Meriem Elyounsi¹⁰,¹¹, Ichraf Kraoua¹²,¹³,
Anissa Zaouak¹⁴, Ilhem Turki¹²,¹³, Mourad Mokni¹⁵,
Sophie Boucher¹⁶,¹⁷, Christine Petit¹⁸,¹⁹, Fabrice Giraudet²⁰,²¹,²²,
Chiraz Mbarek²³, Ghazi Besbes²⁴, Soumeyya Halayem¹,²⁵,
Rim Zainine¹,²⁴, Hamida Turki²⁶, Amel Tounsi²⁷,
CRYSTEL Bonnet¹⁸, Ridha Mrad¹⁰,¹¹, Sonia Abdelhak¹,
Mediha Trabelsi¹⁰,¹¹ and Cherine Charfeddine¹,²⁸

¹Laboratory of Biomedical Genomics and Oncogenetics LR16IPT05, Pasteur Institute in Tunis, University of Tunis El Manar, Tunis, Tunisia, ²Department of Otorhinolaryngology, District Hospital of Menzel Bourguiba, Bizerte, Tunisia, ³Department of Biology, Faculty of Sciences of Bizerte, Université Tunis Carthage, Tunis, Tunisia, ⁴Genetic Typing Service, Institut Pasteur of Tunis, Tunis, Tunisia, ⁵Marseille Medical Genetics (MMG) U1251, Aix Marseille Université, INSERM, Marseille, France, ⁶Department of Pediatrics, La Rabta Hospital, Tunis, Tunisia, ⁷Laboratory of Hereditary Diseases of the Metabolism Investigation and Patients Management, Faculty of Medicine in Tunis, University of Tunis El Manar, Tunis, Tunisia, ⁸Department of Epidemiology and Public Health, Directorate General of Military Health, Faculty of Medicine in Tunis, University of Tunis El Manar, Tunis, Tunisia, ⁹ICHA Association (International Research Institute on Sign Language), Tunis, Tunisia, ¹⁰Department of Congenital and Hereditary Diseases, Charles Nicolle Hospital in Tunis, Tunis, Tunisia, ¹¹LR99ES10 Laboratory of Human Genetics, Faculty of Medicine in Tunis, University of Tunis El Manar, Tunis, Tunisia, ¹²Child and Adolescent Neurology Department of Neurology, National Institute of Neurology, Tunis, Tunisia, ¹³LR18SP04 Department of Child Neurology, National Institute Mongi Ben Hmida of Neurology in Tunis. University of Tunis El Manar, Tunis, Tunisia, ¹⁴Department of Dermatology, Habib Thameur Hospital, Research Unit Genodermatoses and Cancers LR12SP03, Tunis, Tunisia, ¹⁵Service de dermatologie, Hôpital La Rabta, Unité de recherche UR 12SP07, Hôpital La Rabta, Tunis, Tunisia, ¹⁶Service d'ORL et chirurgie cervico-faciale, CHU d'Angers, Angers, France, ¹⁷Equipe Mitolab, Institut Mitovasc, CNRS UMR6015, UMR Inserm 1083, Université d'Angers, Angers, France, ¹⁸Institut Pasteur, Université Paris Cité, Inserm UA06, Institut de l'Audition, Paris, France, ¹⁹Collège de France, Paris, France, ²⁰Unité Mixte de Recherche (UMR) 1107, INSERM, Clermont-Ferrand, France, ²¹Centre Auditif SoluSons, Clermont-Ferrand, France, ²²Service de Génétique Médicale, CHU de Clermont-Ferrand, Clermont-Ferrand, France, ²³ENT Department, Habib Thameur Hospital, Tunis, Tunisia, ²⁴Department of Otorhinolaryngology and Maxillofacial Surgery—La Rabta Hospital in Tunis, Tunis, Tunisia, ²⁵Service de pédopsychiatrie, Hôpital Razi, Faculté de Médecine de Tunis, Université Tunis el Manar, Tunis, Tunisia, ²⁶Dermatology Department Hedi Chaker University Hospital, Sfax University Sfax Tunisia, Tunis, Tunisia, ²⁷CNSS Polyclinic, Bizerte, Tunisia, ²⁸Université de la Manouba, Institut de Biotechnologie de Sidi-Thabet, Ariana, Tunisia

KEYWORDS

syndromic deafness (SD), spectrum of SDs, next-generation sequencing (NGS), early detection, under-diagnosis, Tunisia
A Corrigendum on

Current phenotypic and genetic spectrum of syndromic deafness in Tunisia: paving the way for precision auditory health

by Mkaouar R, Riahi Z, Marrakchi J, Mezzi N, Romdhane L, Boujemaa M, Dallali H, Sayeb M, Lahbib S, Jaouadi H, Boudabbous H, Zekri L, Chargui M, Messaoud O, Elyounsi M, Kraoua I, Zaouak A, Turki I, Mokni M, Boucher S, Petit C, Giraudet F, Mbarek C, Besbes G, Halayem S, Zainine R, Turki H, Tounsi A, Bonnet C, Mrad R, Abdelhak S, Trabelsi M and Charfeddine C (2024). Front. Genet. 15:1384094. doi: 10.3389/fgene.2024.1384094

In the published article, there was an error in the legend for Figure 4 as published. The gene names corresponding to color degradation for the Waardenburg syndrome pie chart are incorrect.

The corrected legend appears below: The SOX10 gene should be at the top (darkest blue), and the EDNRB gene should be at the bottom (lightest blue). Consequently, the number of patients should be 8 for the SOX10 gene and 2 for the EDNRB gene.

In addition, there was an error in the caption of Figure 4 in the published version of the manuscript: "FIGURE 4: Genetic and mutational spectrum of syndromic deafness in the Tunisian population. Deafness syndromes with known molecular etiologies are represented by pie charts. Each syndromic deafness is indicated with a different color. Color degradation has been adopted to specify

the gene(s) associated with each syndrome. The number of variants identified in each gene is provided.”

The corrected Figure 4 appears below:

The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher's note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

<figure><img src="image_4.png" /><figcaption>FIGURE 4
Genetic spectrum of syndromic deafness in the Tunisian population. Deafness syndromes with known molecular etiologies are represented by pie charts. Each syndromic deafness is indicated with a different color. Color degradation has been adopted to specify the gene(s) associated with each syndrome. The number of patients carrying variants in each gene is provided.</figcaption></figure>