# Saving time and money in biomedical publishing: the case for free-format submissions with minimal requirements

Amy Clotworthy, Megan Davies, Timothy J. Cadman, Jessica Bengtsson, Thea O. Andersen, Manik Kadawathagedara, Johan L. Vinther, Tri-Long Nguyen, Tibor V. Varga

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Amy Clotworthy, Megan Davies, Timothy J. Cadman, Jessica Bengtsson, Thea O. Andersen, et al. Saving time and money in biomedical publishing: the case for free-format submissions with minimal requirements. BMC Medicine, 2023, 21, pp.172. 10.1186/s12916-023-02882-y. hal-04664046

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# Saving time and money in biomedical publishing: the case for free-format submissions with minimal requirements

Amy Clotworthy¹,², Megan Davies¹, Timothy J. Cadman¹, Jessica Bengtsson¹, Thea O. Andersen¹, Manik Kadawathagedara¹, Johan L. Vinther¹, Tri-Long Nguyen¹ and Tibor V. Varga¹*

**Abstract**

**Background** Manuscript preparation and the (re)submission of articles can create a significant workload in academic jobs. In this exploratory analysis, we estimate the time and costs needed to meet the diverse formatting requirements for manuscript submissions in biomedical publishing.

**Methods** We reviewed 302 leading biomedical journals' submission guidelines and extracted information on the components that tend to vary the most among submission guidelines (the length of the title, the running title, the abstract, and the manuscript; the structure of the abstract and the manuscript, number of items and references allowed, whether the journal has a template). We estimated annual research funding lost due to manuscript formatting by calculating hourly academic salaries, the time lost to reformatting articles, and quantifying the total number of resubmissions per year. We interviewed several researchers and senior journal editors and editors-in-chief to contextualize our findings and develop guidelines that could help both biomedical journals and researchers work more efficiently.

**Results** Among the analyzed journals, we found a huge diversity in submission requirements. By calculating average researcher salaries in the European Union and the USA, and the time spent on reformatting articles, we estimated that ~230 million USD were lost in 2021 alone due to reformatting articles. Should the current practice remain unchanged within this decade, we estimate ~2.5 billion USD could be lost between 2022 and 2030—solely due to reformatting articles after a first editorial desk rejection. In our interviews, we found alignment between researchers and editors; researchers would like the submission process to be as straightforward and simple as possible, and editors want to easily identify strong, suitable articles and not waste researchers' time.

**Conclusions** Based on the findings from our quantitative analysis and contextualized by the qualitative interviews, we conclude that free-format submission guidelines would benefit both researchers and editors. However, a minimum set of requirements is necessary to avoid manuscript submissions that lack structure. We developed our guidelines to improve the *status quo*, and we urge the publishers and the editorial-advisory boards of biomedical journals to adopt them. This may also require support from publishers and major international organizations that govern the work of editors.

**Keywords** Publishing, Journal article, Formatting, Submission guidelines, Policy

<footnote>*Correspondence:
Tibor V. Varga
tibor.varga@sund.ku.dk
Full list of author information is available at the end of the article</footnote>
## Background

Since the introduction of the first printed journal in 1665, the intent behind publishing papers has been to advance scientific knowledge by building on other scholars' results and avoiding duplications [1]. The structured format that developed over time has enabled the systematic recording and archiving of scientific knowledge [2–5]. However, with the advent of digital and online formats, the need to format manuscripts according to a journal's specific layout for a printed issue (which was often dictated by the press being used) has become obsolete. Although the digital format has improved access, searchability, and navigation within and between journal articles, it has not substantially changed the form of the scholarly journal [6].

When academic authors currently format a manuscript to adhere to a journal's submission guidelines, it means that their documents should arrive in editorial in-boxes with a specific structure and length, following certain formatting for figures and tables, author information, reference style—the list goes on. In theory, the main benefit of such standardized formatting is that it facilitates the evaluation process at both the editorial and the peer-review stage [7]. Several prominent journals even warn authors that failure to comply with their specified guidelines may result in a rejection of a submitted article (or its return to the authors), which may significantly delay the publishing process [8–11].

However, initial manuscript submission guidelines vary substantially among journals. This places a time constraint and financial strain on authors in terms of formatting and reformatting their articles [12]. Informally, authors have raised numerous issues concerning the current complexity of journal systems, processes, and guidelines. Stressing the amount of time spent on the process of formatting and submitting manuscripts, authors have expressed a preference for (1) clean, simple manuscript-submission guidelines, (2) standardized formatting guidelines, and (3) universal online-submission systems [13].

As the problematic nature of varying submission requirements has been raised several times [14–19] and reported to be a significant burden for authors [13], some journals have developed their own standardized templates, moved towards “free-format” first submissions, or may be willing to evaluate papers posted on pre-print servers [20] to simplify the process. Despite these improvements, the overall academic-publishing industry has experienced only a marginal shift, with publishers/ journals taking individual action rather than collaborating on a shared solution [1]. We believe that these sporadic improvements are laudable; however, varying submission requirements will continue to put time and

financial burden on researchers and slow the process of scientific dissemination until a single unifying solution to streamline manuscript submission is found.

In our exploratory analysis, we reviewed 302 leading biomedical journals' submission requirements to estimate the time and costs needed to meet the diverse formatting requirements for an initial submission in biomedical publishing. To gain insight into the processes involved, we sought the experiences and perspectives of not only authors but also journal editors. Based on our findings from the quantitative study and the subsequent qualitative contextualization, in this article, we propose concrete suggestions for journal guidelines that will both decrease the time needed for submission and reduce the financial burden the current system imposes on academia.

## Methods

To review current formatting requirements, we extracted a list of the top 1000 academic journals [21] based on their 2019 CiteScore values, a metric used to measure the average citations per document in a particular journal over a certain period of time [22]. We excluded journals that do not publish original research articles (n=181) and, from the remaining list, all that are non-biomedical journals (n=427); we present the detailed selection process in Additional file 1: Text S1. We then sorted the remaining list (n=392) by decreasing CiteScore values and included the top 302 biomedical journals for review. The 302 journal titles were divided among all co-authors, who then manually extracted the eight components that we found to vary the most among submission guidelines: the maximum length of the title, running title, abstract, and manuscript text; the structure of the abstract and the manuscript; the maximum number of items (tables and/ or figures) and references allowed; and the availability of a submission template on the journal's website (Additional file 2: Table S1). If questions arose, the specific co-author and the senior author discussed and resolved them. The co-authors calculated the number of possible formats by computing the number of possible combinations of the eight criteria on which we focus in our review.

We extracted average annual salaries in the European Union and the United States for PhD students, postdocs, assistant professors, associate professors, and full professors, and we averaged these values to calculate an *average researcher salary* in these regions [23–25]. Using an estimate of ~1750 work hours per year, which is the Organisation for Economic Co-operation and Development (OECD) average for the European Union and the United States [26], we calculated average hourly salaries. Using the four hours of reformatting time per article that Sobani et al. estimated in a previous report [15] and,
assuming that each article is desk-rejected and resubmitted once (on average), also proposed by Sobani et al. [15], we estimated the cost of reformatting one article. We then extracted the number of entries published in PubMed each year between 2000 and 2021 [27]. Based on the salary estimates and the number of articles, we estimated the annual financial loss between 2000 and 2021. We then used a time-series prediction using quadratic models with years as a predictor using the *lm*() function in R (v.4.2.2) [28] to extrapolate financial loss between 2022 and 2030.

We also conducted semi-structured qualitative interviews with four mid-career researchers and four senior journal editors or editors-in-chief between 19 July and 18 August 2022. Seven interviews were conducted via secure video calls, while one researcher provided email comments to our list of questions. All of the interviews were conducted in English; for seven out of eight of the participants, English was their primary working language but not their first language (i.e., native tongue). The predetermined interview questions and follow-up questions were developed by (i) surveying co-authors for suggestions and (ii) informally soliciting suggestions from other colleagues during departmental seminars. The most relevant quotes from the interviews were transcribed, and all personally identifying features were removed from the transcripts. The complete process of the qualitative interviews is described in Additional file 3: Text S2 [29–35].

## Results

### Diversity in formatting requirements

In our analysis, we identified significant diversity in initial formatting requirements. For each category, a substantial proportion of journals did not specify requirements (or we were unable to locate them). In particular, the following percentage of journals did not indicate information related to running titles and their length (65%), length of the title (64%), maximum number of references (58%), number of figures and tables (48%), main text length (34%), manuscript structure (27%), abstract structure (21%), and abstract length (14%). The lack of information regarding these parameters did not necessarily promote free-format submission; for example, we differentiated between journals explicitly stating no word limit for the main text (3%) and those for which this information was not available (or we were unable to locate it) (34%). This high percentage of missing information suggests that submission guidelines are incomplete and/or difficult to navigate, adding an additional burden to the already cumbersome process of (re)formatting a manuscript.

We categorized the requirements for maximum length and overall structure; where these were specified, running-title lengths tended to be between 50 and 59

characters (15%), title lengths were between 150 and 200 characters (13%), abstract word limits were between 200 and 300 words (65%), main text word limits were between 2500 and 4000 words (32%), the number of items were 6–7 (19%), and the number of references were between 45 and 60 (17%) (Fig. 1). With regard to abstracts, 21% did not specify a structure (or we did not find it), 22% required unstructured abstracts, and the remaining 57% required a structured abstract, with Background, Methods, Results, and Conclusions being the most frequently specified sections (Fig. 2). In terms of manuscript structure, the Introduction, Methods, Results, and Discussion format (known as IMRaD) was the most frequently specified (43%) (Fig. 3). While journals belonging to the same family (e.g., *Journal of the American Medical Association* [JAMA] family, *Science* family) usually follow the same formatting conventions, the vast majority of journals we analyzed had a unique set of requirements. We acknowledge that the selection process of leading biomedical journals (i.e., those with the highest CiteScore values) might bias our findings; however, we find it unlikely that selecting journals with lower average scores or selecting journals according to other criteria would significantly impact our conclusions regarding either the diversity or the variation in submission requirements.

In our calculation of the number of possible formats, we obtained a staggering number of ~6.3 billion possible unique sets of formatting requirements. In the next section, we review and estimate the financial cost of reformatting articles for a new submission.

### The cost of (re)formatting articles

We obtained average annual salaries in the European Union and the United States for PhD students (33,000 USD), postdoctoral researchers (43,000 USD), assistant professors (56,000 USD), associate professors (67,000 USD), and full professors (86,000 USD), and then calculated an *average researcher salary* of 57,000 USD. With an estimate of ~1750 work hours per year, we arrived at an average hourly salary of 32.6 USD. Using four hours of reformatting time, we estimated the cost of reformatting one article to be approximately 130 USD. In 2000, the number of published entries on PubMed was ~0.5 million, while in 2021, a record number of ~1.8 million were published. Assuming one rejection per paper (on average), we calculated that ~230 million USD were lost in 2021 alone. Should the current practice remain unchanged within this decade, we estimate ~2.5 billion USD could be lost between 2022 and 2030—solely due to reformatting articles after a first editorial desk rejection. These estimates are depicted in Fig. 4, which also shows projected losses with an error bound based on a previously reported minimum estimate of one hour [14,
<figure><img src="image_3.png" /><figcaption>**Fig. 1** Diversity in submission requirements based on the review of leading biomedical journals (N = 302)</figcaption></figure>

[16] and a maximum estimate of 14 h per article [12]. The extrapolated financial loss for the period 2022–2030 roughly equates to 75 million hours of lost time. Calculating based on 1750 work hours per year, this means that there could be a cumulative delay of approximately 43,000 years in the public dissemination of results—solely due to the reformatting of papers from 2022 to 2030.

# Discussion

## Our results in context

For many authors, the first step in publishing a scientific article is identifying the most appropriate journal(s) to disseminate their research, and then formatting the

manuscript according to the target journal's submission guidelines. The percentage of papers rejected without peer-review can vary across journals, disciplines, and publishing models, with some journals rejecting more than two-thirds of all first submissions at the editorial level [36]; this is known as a 'desk reject'. When an article is returned to the corresponding author, they often want to resubmit to another journal quickly to avoid delays in dissemination. Once the author identifies another appropriate journal, they must then understand its specific submission requirements. It is at this stage that reformatting can be particularly cumbersome and time-consuming; numerous tasks are involved in reformatting manuscripts to adhere to the second
<figure><img src="image_4.png" /><figcaption>**Fig. 2** Word cloud of abstract sections in leading biomedical journals (N = 302)</figcaption></figure>

<figure><img src="image_5.png" /><figcaption>**Fig. 3** Main text structures in leading biomedical journals (N=302). C—Conclusions; D—Discussion; I—Introduction; M—(Materials and) Methods; R—Results</figcaption></figure>

journal's specific requirements, as well as additional
tasks related to the submission process itself.

Sobani et al. estimated that the total time used to resubmit one article is ~ four hours for submitting authors [15]. Others have estimated that reformatting a single manuscript can take from one to 14 h or more [12, 14, 16]. In practice, the time needed to reformat can be substantially longer, especially when the resubmission requires substantive reductions to the manuscript's word count. For instance, an

article rejected by *Science* (max. 4500 words) cannot be immediately resubmitted to *The Lancet* (max. 3500 words) or *The New England Journal of Medicine* (max. 2700 words). Such substantive differences in length also exist among the specialized journals, a specific barrier that was mentioned in our interviews. One researcher said, "*For a typical manuscript, [reformatting takes] a couple of days ... If you have to rewrite a lot because you have to cut 2,000 words, then it probably takes more time*".
<figure><img src="image_6.png" /><figcaption>**Fig. 4** The cost of reformatting manuscripts after editorial rejections. We estimated the cost of reformatting one original research article to be approximately 130 USD. The number of entries published in PubMed was extracted for each year between 2000 and 2021. We assumed that each manuscript needs to be reformatted once (on average) before submission to another journal. Between years 2022 and 2030, we predicted the lost research funds using a quadratic model with calendar year as predictor. The error bound was calculated using a previously reported minimum estimate of one hour and a maximum estimate of 14 h per article</figcaption></figure>

When significant rewriting takes place, the correspond-
ing author will typically circulate a revised manuscript to
any co-authors in order to obtain their approval for the
new submission. In these cases, one of the researchers
said, "*It could take a week [because] if we need to add an
extra section, then we need to talk again between the dif-
ferent authors*". Reducing the word count is not the only
challenge. Often, additional changes need to be imple-
mented throughout the manuscript; e.g., the number of
figures and tables, adjustments to the abstract text/struc-
ture, reference style, or the title. As one researcher put
it, "*When you need to reformat, it takes forever, because
sometimes [journals] are really picky with some detail
that you really have to follow, and they won't send it out
to review if it doesn't fulfil their formatting criteria*". How-
ever, we did find that approximately 11% of the journals
in our study provided a template on their website to
guide authors with formatting.

Our estimate of the financial loss per article was lower
than others found in the literature. A report by LeBlanc
et al. surveyed ~400 individuals on the topic of resubmit-
ting papers and arrived at an estimate of 477 USD lost
per paper. This estimate took into account 14 h of work
per manuscript and a median number of two resubmis-
sions per paper based on survey responses [12]. Using
this estimate, they calculated a loss of 1908 USD per
year in research funding for each author. Sobani et al.

estimated 2.6 million hours of lost academic work per
year based on half a million biomedical articles annu-
ally, three hours of resubmission time, and one rejection
per submitted article [15]. Another report by Khan et al.
arrived at approximately 1.5 million hours lost in refor-
matting rejected articles per year, based on an average
rejection rate of 62% for 2.5 million published papers
every year, and one hour spent on reformatting time per
manuscript [14]. Single author Budd estimated the time
lost due to resubmission after editorial rejection by the
journal *Nature* alone (desk-rejection rate: 92%). They
concluded ~ 10,000 h of work time were lost per year,
based on one hour of work per article to be resubmitted
elsewhere [16]. Finally, Jiang et al. estimated the annual
cost of reformatting manuscripts to be ~ 1.1 billion USD,
a fivefold increase on our calculations [37].

We believe that our calculations are conservative esti-
mates; the real cost in lost time and money is likely to be
higher. Research is a collaborative process, and reformat-
ting articles results in wasted time for everyone in the
finite academic ecosystem, including all authors, peer-
reviewers, editors, publishers, and ultimately, the public.

Thus far, we have shown that reformatting manuscripts
takes an enormous toll on the research ecosystem in
terms of both time and money. Next, we propose a sim-
ple solution that could help to prevent these projections
from being realized.
## Potential routes to decrease the time and financial burden of submissions

Based on our investigation, we have identified two possible solutions (Fig. 5) that could significantly decrease the time and money lost due to heterogeneous initial-submission guidelines. The first suggestion is to adopt the *same* universal guidelines across all biomedical journals. The second is to remove the requirement for specific formatting at first submission; in this case, journals could request specific formatting guidelines but only *after* acceptance [14].

Both solutions have benefits and drawbacks. While universal guidelines would drastically reduce the burden on authors, this approach could force journals to lose their distinctive 'look' (house style) as well as remove flexibility specific to their subject matter or print format. But, in practice, it is unlikely to impact the editorial process. For example, one editor told us: "*There are journals that in principle have formats but don't care. [...] The editor hardly ever cares about how long [the text] is or how many figures it has on first instance*". The introduction of universal submission guidelines could also be

a costly endeavor for journals/publishers, which could lead to resistance, as another editor noted: "*It would be a very high lift to get all publishers together and agree on universal submission guidelines. And people use different submission systems that have different dependencies. [...] If you're an editor at one journal, you'll know that in a way we're at the tyranny of very clunky submission systems that are not very good. [...] Changing that is very costly for individual publishers.*"

The second option of a free-format first submission is now easier than ever. An increasing number of journals are published online-only, so articles in these journals require less post-processing upon acceptance, and there are fewer restrictions on length. Indeed, the editors we interviewed indicated that there is an increasing trend towards free-format initial submission. One said, "*My understanding [is that] less and less journals [...] have rigid format restrictions. I think most journals are [...] moving towards initial-submission agnostic views*". Another said, "*Some journals have introduced what they call 'hassle-free' submission [and] our journal is moving towards it*". Despite this development, the number of

<figure><img src="image_7.png" /><figcaption>**Fig. 5** The two possible avenues for simplifying the submission process and our proposed solution: free-format initial submissions with a minimum set of requirements</figcaption></figure>
journals with free-format initial submissions is still esti-
mated at only around ~5% of all biomedical journals [37].

With regard to a free-format approach, several editors raised concerns about the burden of having to review papers that were unreasonably long, poorly structured, or just badly written. For example, one editor noted, “Sometimes you get submissions [...] which are, basically, somebody’s whole PhD thesis just dumped there”. Another editor said: “Every so often somebody sends me an article that [...] looks like [...] somebody had a dictaphone in their hand and just spoke to it for 20 minutes and got someone to transcribe it”. For a format-free approach to be successful, this same editor reflected that, “It would depend on everybody submitting having a vague sense of what a scientific article looks like”. Thus, the key point in favor of a free-format approach was nicely summarized as such: “I like the articles to be standardly structured. But there is flexibility around that. It doesn’t always have to be the same. It should be recognizable as a scientific article.”

Considering both options and taking the experiences of both researchers and journal editors into account, we propose a ‘golden middle’. Specifically, we believe that free-format submission guidelines are the way forward, but a minimum set of structural requirements is necessary to avoid the submission of manuscripts that are excessively long or simply not “recognizable as a scientific article”.

Our proposed minimum set of requirements, pre-
sented in Table 1, was developed based on the current
submission requirements of the 302 biomedical journals
we reviewed as well as on our interviews with the editors.
We propose no requirements regarding titles, running
titles, title pages, abstract structure, item formatting,
maximum number of items, maximum number of refer-
ences, or reference styles at first submission—we believe
that these details can be addressed later during the
‘revise and resubmit’ stage, or even after acceptance. As
we learned from our interviews with the editors, it is at
the resubmission stage when most journals tend to com-
mit to shepherding manuscripts towards acceptance and
publication: “Where we do a lot of checking is when the
revised version comes back in. Because we have a strong
commitment to revisions”. Similarly, another editor said,
“We don’t bother with any format until we are inviting
for revision. When we invite for revision, we are pretty

confident. [...] After peer-review, that's when we make a
commitment."

As outlined in Table 1, even the two requirements that we propose allow for flexibility. In cases where a journal may have additional specific requirements/sections (e.g., clinical relevance, key messages, graphical abstract), we encourage them to ask authors to upload these parts in separate files to keep the main manuscript easy to resubmit to another journal. If print journals with space constraints need to enforce word limits that are stricter than those defined in our minimum set of requirements, then we propose that these journals still adopt the same basic requirements and also that they should also be willing to review longer papers. However, they should clearly explain to the submitting author(s) that word count will need to be reduced upon acceptance in order to adhere to their pre-specified maximum lengths.

Furthermore, we recommend that online content-man-
agement systems incorporate auto-fill tools that require
an initial upload of the manuscript file and then use the
available information to populate fields in the system.
Manually copying titles, abstracts, and key words as well
as filling in authorship and funding information can sub-
stantially prolong the submission process. For example,
one researcher explained, “In the submission system, there
are a lot of steps that we need to go through. [...] You have
to write the name, the address—things that you already
have on the first page of the article. [...] And the names are
not recognized by the system. These are unnecessary things
that really waste time.” These manual processes can also
be prone to error, especially when manuscripts have many
authors and/or funders. Oftentimes, following a submis-
sion of a manuscript, all co-authors need to register their
profile on the journal-submission site, provide informa-
tion related to expertise, keywords, and fill in other fields;
e.g., the newly introduced mandatory diversity and inclu-
sion surveys (which we fully support—after acceptance),
and then proceed to approve the corresponding author’s
submission. When a manuscript has multiple co-authors,
such processes can cause significant delays. One of the
editors we interviewed had had similar experiences on
both sides of the editorial desk, explaining, “I’ve pub-
lished articles [...] where it is a bloody pain trying to work
it out how to format it for [a journal], and jump through
the ludicrous hoops of their content-management system.

<caption>**Table 1** A minimum set of requirements for the first submission of an original research article</caption>

* Abstract of maximum ~ 300 words that includes information on the project background, methods, results, and conclusions

* Main body of maximum ~ 3000–5000 words, with sections that include information on the project background, methods, results, and discussion and contextualization of findings

* If the manuscript differs substantially from these requirements, please explain the reasons for this to the managing editor (e.g., via the cover letter or the comment box during submission)
[...] I've used most of the content-management systems or editorial management systems, and found that all of them tripped me up at various points". Artificial-intelligence tools already implemented by some journals can automatically recognize and process these sections, which can save significant time for the corresponding author. If journals do not have the means to incorporate such tools, then we suggest requesting this detailed information only at the resubmission/acceptance stage.

From our interviews, we were struck by how much alignment there was between the editors and the researchers. As we learned, researchers/authors would like the submission process to be as straightforward and simple as possible, and editors want to easily identify strong, suitable articles and not waste the authors' time. Most editors emphasized that the manuscript's scientific content and its relevance to the journal's aims and scope were far more important than any formatting details. As one editor put it: "I didn't care what format they were in, I just cared about the science in the paper."

## Conclusions

Based on this study, we urge publishers and the editorial-advisory boards of biomedical journals—who have the mandate to make these changes—to follow the increasing trend to adopt free-format initial submissions and to implement our proposed minimum set of requirements. In addition, we recommend that influential associations insist that publishers and journals adopt free-format first submissions with our proposed minimum set of requirements. Organizations that are likely to have a vested interest in the changes we are proposing are editorial associations (e.g., International Committee of Medical Journal Editors [ICMJE], World Association of Medical Editors), academic and university organizations (e.g., Association of American Universities, League of European Research Universities), and certain funding bodies (e.g., National Institutes of Health [NIH], the European Research Council [ERC], and the Wellcome Trust). Most important, large publishing houses are in the strongest position to make a meaningful impact by implementing our proposed guidelines across their portfolios of hundreds of journals.

We are not the only ones demanding this change. As one editor noted, "There's a clamour [for reform] on Twitter. Every week there's stuff going on about formats and submission. People do want them to be liberalized [because] it's a waste of time". Based on the results of our study, we believe now is the time to act and spark institutional change in the scientific community that will ultimately enable researchers and editors alike to use their precious time to advance science and not endlessly format papers. We would like to stress that we do not call

for the abolition of journals' unique house styles, formats, and designs; we simply believe that the simplified process of submissions that we propose here would drastically reduce the time and financial demands being experienced by an already overburdened research ecosystem. As one editor put it: "Just send [the article] in to us, and we'll take a look at it. And if we like it, we'll send it out for peer review. And if it meets peer review, we'll send it back to you. And THEN you can put it into our journal's format. I think that's respectful of the authors' time and effort."

## Abbreviations

<table><tr><td>ERC</td><td>European Research Council</td></tr><tr><td>ICMJE</td><td>International Committee of Medical Journal Editors</td></tr><tr><td>IMRaD</td><td>Introduction, Methods, Results, and Discussion format</td></tr><tr><td>JAMA</td><td>Journal of American Medical Association</td></tr><tr><td>NIH</td><td>National Institutes of Health</td></tr><tr><td>OECD</td><td>Organisation for Economic Co-operation and Development</td></tr></table>

## Supplementary Information

The online version contains supplementary material available at https://doi.org/10.1186/s12916-023-02882-y.

**Additional file 1: Text S1.** Selection process of the 302 biomedical journals for quantitative analysis. This document outlines the selection process used to identify the journals included in our quantitative analysis. It provides a list of all the journal categories that were excluded and describes how we arrived at our final selection of 302 journals that were included in the analysis.

**Additional file 2: Table S1.** Initial submission guidelines for leading biomedical journals. This anonymized table presents the quantitative statistics extracted from the 302 selected biomedical journals. The data we collected from these journals include the maximum character count for the title and running title, the maximum word count for the abstract and manuscript body, the maximum number of items, the maximum number of references, abstract sections, main sections, and whether a template is available for authors.

**Additional file 3: Text S2.** Interview protocol and questions for researchers and editors. This document contains a detailed description of the interview protocol used for the researchers and journal editors, including ethical considerations related to the qualitative aspect of our study and the informed consent form. The file also includes email templates that were sent to the researchers and editors we attempted to interview. It outlines the questions asked of the informants, as well as any follow-up questions.

## Acknowledgements

We would like to thank all of the researchers and editors who participated in this project—we appreciate you taking the time out of your busy schedules to share your experiences and insights. Not only did your perspectives enhance our knowledge about the formatting process, they made us even more motivated to publish this article and our petition for change.

## Authors' contributions

The corresponding authors attest that all listed authors meet the ICMJE authorship criteria and that no others meeting the criteria have been omitted. TVV is the guarantor of this manuscript. TVV wrote the first draft of the manuscript. TVV and TLN were responsible for the conceptualization of the project. JB, MK, and TOA performed the literature review. MD and TVV visualized the findings. AC, JLV, JB, MD, MK, TJC, TLN, and TVV reviewed the biomedical journals. AC and TJC designed the interview guide and conducted the interviews. AC, TJC, and TVV analyzed the interviews. AC, JLV, JB, MD, MK, TJC, TLN, and TVV reviewed and edited the manuscript and approved the final, submitted
version. AC, JLV, JB, MD, MK, TJC, TLN, and TW confirm that they had full access to the data in the study and accept responsibility for the content of this publication. The author(s) read and approved the final manuscript.

## Funding

TVV is supported by the "Data Science Investigator—Emerging 2022" grant from Novo Nordisk Foundation (NNF2200075284). AC is supported by the Center for Healthy Aging and Nordea Fonden (02-2017-1749). No specific funding declared for this project. No funding body had any impact on the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.

## Availability of data and materials

All data used in our analyses are available in the Supplemental Material.

## Declarations

### Ethics approval and consent to participate

No ethical approval was needed to complete this project. All informants provided informed consent.

### Consent for publication

Not applicable.

### Competing interests

The authors declare that they have no competing interests.

## Author details

¹Section of Epidemiology, Department of Public Health, University of Copenhagen, Bartholingsgade 6Q, DK-1356 Copenhagen K, Denmark. ²Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Received: 13 December 2022 Accepted: 26 April 2023

Published online: 10 May 2023

## References

1. Larivière V, Haustein S, Mongeon P. The oligopoly of academic publishers in the digital era. PLoS ONE. 2015;10(6):e0127502.

2. Haustein S. Multidimensional journal evaluation. In: Multidimensional Journal Evaluation. De Gruyter Saur; 2012.

3. Tenopir C, King DW. The growth of journals publishing. In: The future of the academic journal. Chandos: Publishing; 2014. p. 159–78.

4. Zuckerman H, Merton RK. Patterns of evaluation in science: institutionalisation, structure and functions of the referee system. Minerva. 1971;1:66–100.

5. Price DJ. Little science, big science... and beyond, vol. 480. New York: Columbia University Press; 1986.

6. Kling R, Callahan E. Electronic journals, the Internet, and scholarly communication. 2001.

7. Overstreet K. Why manuscript formatting can reduce you to a whiny 4-year-old. J Spec Pediatr Nurs. 2010;15(1):4.

8. Kern MJ, Bonneau HN. Approach to manuscript preparation and submission: how to get your paper accepted. Catheter Cardiovasc Interv. 2003;58(3):391–6.

9. Cash TF. Caveats in the proficient preparation of an APA-style research manuscript for publication. Body image. 2009;6(1):1-6.

10. Setiati S, Harimurti K. Writing for scientific medical manuscript: a guide for preparing manuscript submitted to biomedical journals. Acta Med Indones. 2007;39(1):50–5.

11. Peh WC, Ng KH. Preparing a manuscript for submission. Singapore Med J. 2009;50(8):759–61.

12. LeBlanc AG, Barnes JD, Saunders TJ, Tremblay MS, Chaput J-P. Scientific sinkhole: the pernicious price of formatting. PLoS ONE. 2019;14(9):e0223116.

13. Awati M. Guest Post — a case for universal and simplified journal systems. The Scholarly Kitchen. https://scholarlykitchen.sspnet.org/2019/08/20/guest-post-a-case-for-universal-and-simplified-journal-systems/. Accessed: 29 Aug 2022.

14. Khan A, Montenegro-Montero A, Mathelier A. Put science first and formatting later. EMBO Rep. 2018;19(5):e45731.

15. Sobani ZA, Horovitz J, Kamholz S. Streamlined manuscript submission guidelines: beyond overdue. Ann Med Surg. 2018;25:1.

16. Budd J. Reformatting wastes public funds. Nature. 2017;543(7643):40–40.

17. Guo Q. Journals, agree on manuscript format. Nature. 2016;540(7634):525–525.

18. Moore JP. Journals, do your own formatting. Nature. 2017;542(7639):31–31.

19. Galichon P, Bataille A. A call to improve the submission process. The Lancet. 2016;387(10019):648.

20. Hoy MB. Rise of the Rxivs: how preprint servers are changing the publishing process. Med Ref Serv Q. 2020;39(1):84–9.

21. Kaggle. Impact factor of top 1000 journals. https://www.kaggle.com/datasets/umairnasir14/impact-factor-of-top-1000-journals. Downloaded: 1 May 2022

22. Roldan-Valadez E, Salazar-Ruiz SY, Ibarra-Contreras R, Rios C. Current concepts on bibliometrics: a brief review about impact factor, Eigenfactor score, CiteScore, SCImago journal rank, source-normalised impact per paper, H-index, and alternative metrics. Irish J Med Sci. 2019;188:939–51.

23. Shulman S, Hopkins B, Kelchen R, Persky J, Yaya M, Barnshaw J, Dunietz SJ. Visualizing change: the annual report on the economic status of the profession. Academe. 2017;103(2):4.

24. Woolston C. Huge variations in US postdoc salaries point to undervalued workforce. Nature: Career News 2019. https://www.nature.com/articles/d41586-019-00587-y. Accessed 2 May 2023.

25. Salary Comparisons. URL: https://www.eui.eu/ProgrammesAndFellows/hips/AcademicCareersObservatory/CareerComparisons/SalaryComparisons (Accessed: 1 Mar 2023)

26. OECD: OECD Compendium of Productivity Indicators 2023. https://stats.oecd.org/Index.aspx?DataSetCode=ANHRS. 2023. Accessed 21 Mar 2023.

27. Corlan AD. Medline trend: automated yearly statistics of PubMed results for any query. 2004. http://dan.corlan.net/medline-trend.html. Accessed 2 May 2023.

28. R Core Team. R: a language and environment for statistical computing. Vienna: R Foundation for Statistical Computing.

29. Naderifar M, Goli H, Ghaljaie F. Snowball sampling: a purposeful method of sampling in qualitative research. Strides Develop Med Educ. 2017;14(3):e67670.

30. Madden R. Being ethnographic: a guide to the theory and practice of ethnography. SAGE; 2017.

31. Braun V, Clarke V. What can “thematic analysis” offer health and wellbeing researchers? Int J Qual Stud Health Well-being. 2014;9:26152.

32. European Parliament. GDPR is in effect: now you decide on your digital privacy. 2018. https://www.europarl.europa.eu/news/en/headlines/socie ty/20180522STO04023/gdpr-is-in-effect-now-you-decide-on-yourdigital-privacy. Accessed 8 June 2021.

33. Danish Ministry of Justice. Act on supplementary provisions to the regulation on the protection of natural persons with regard to the processing of personal data and on the free movement of such data (the data protection act. Act No. 502). 2018.

34. Danish Ministry of Higher Education and Science (Uddannelses- og Forskningsministeriet). Danish code of conduct for research integrity. 2014. https://ufm.dk/en/publications/2014/the-danish-code-of-conduct-for-research-integrity. Accessed 8 June 2021.

35. University of Copenhagen Practice Committee (Praksisudvalget). Rules and guidelines. 2021. https://praksisudvalget.ku.dk/english/rules_guide/. Accessed 8 June 2021.

36. The BMJ Publishing Model. https://www.bmj.com/about-bmj/publi shing-model. Accessed 29 Aug 2022.

37. Jiang Y, Lerrigo R, Ullah A, Alagappan M, Asch SM, Goodman SN, Sinha SR. The high resource impact of reformatting requirements for scientific papers. PLoS ONE. 2019;14(10):e0223976.

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