# GLIS2 wt Allele

National Cancer Institute

## Source

National Cancer Institute. *GLIS2 wt Allele*. NCI Thesaurus. Code C105901.

Human GLIS2 wild-type allele is located in the vicinity of 16p13.3 and is approximately 25 kb in length. This allele, which encodes zinc finger protein GLIS2, plays a role in the modulation of both signaling and transcription. Mutation of the gene is associated with type 7 nephronophthisis.