# MLF1 wt Allele

National Cancer Institute

## Source

National Cancer Institute. MLF1 wt Allele. NCI Thesaurus. Code C97651.

Human MLF1 wild-type allele is located in the vicinity of 3q25.1 and is approximately 36 kb in length. This allele, which encodes myeloid leukemia factor 1 protein, is involved in both cell cycle arrest and the regulation of transcription. A chromosomal translocation t(3;5) (q25.1;q34) of this gene and the NPM1 gene is associated with myelodysplastic syndrome.