# Screening of potential antiviral molecules against equid herpesvirus-1 using cellular impedance measurement: dataset of 2,891 compounds

Côme Thieulent, Christine Fortier, Hélène Munier-Lehmann, Peggy Suzanne, Patrick Dallemagne, Stéphan Zientara, Aymeric Hans, Romain Paillot, Pierre-Olivier Vidalain, Stéphane Pronost, et al.

<figure><img src="image_1.png" /></figure>

## ► To cite this version:

Côme Thieulent, Christine Fortier, Hélène Munier-Lehmann, Peggy Suzanne, Patrick Dallemagne, et al. Screening of potential antiviral molecules against equid herpesvirus-1 using cellular impedance measurement: dataset of 2,891 compounds. Data in Brief, 2020, 33, pp.106492. 10.1016/j.dib.2020.106492. hal-03022297

HAL Id: hal-03022297

https://normandie-univ.hal.science/hal-03022297

Submitted on 24 Nov 2020

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers.

L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.

<figure><img src="image_2.png" /></figure>

Distributed under a Creative Commons Attribution 4.0 International License
<figure><img src="image_3.png" /></figure>

Data Article

Screening of potential antiviral molecules
against equid herpesvirus-1 using cellular
impedance measurement: Dataset of 2,891
compounds.

<figure><img src="image_4.png" /></figure>

Côme Thieulent<sup>a,b</sup>, Christine Fortier<sup>a,b,c</sup>, Hélène Munier-Lehmann<sup>d</sup>, Peggy Suzanne<sup>e</sup>, Patrick Dallemagne<sup>e</sup>, Stephan Zientara<sup>f</sup>, Aymeric Hans<sup>g</sup>, Romain Paillot<sup>a,b</sup>, Pierre-Olivier Vidalain<sup>h,i</sup>, Stéphane Pronost<sup>a,b,c</sup>, Erika Hue<sup>a,b,c,*</sup>

ARTICLE INFO

Article history:
Received 11 September 2020
Revised 29 October 2020
Accepted 30 October 2020
Available online 5 November 2020

A B S T R A C T

Data presented in this article are associated with the re-
search article "Identification of antiviral compounds against
equid herpesvirus-1 using real-time cell assay screen-
ing: efficacy of decitabine and valganciclovir alone and
in combination" [1]. These data correspond to the in
vitro screening of 2,891 potential antiviral compounds
against equid herpesvirus-1 (EHV-1) based on impedance
measurements using the xCELLigence® RTCA MP System.

<footnote><sup>a</sup>LABÉO Frank Duncombe, 14280 Saint-Contest, France</footnote>

<footnote><sup>b</sup>Normandie Univ, UNICAEN, BIOTARGEN EA7450, 14280 Saint-Contest, France</footnote>

<footnote><sup>c</sup> Normandie Univ, UNICAEN, ImpedanCELL, 14280 Saint-Contest, France</footnote>

<footnote><sup>d</sup>Institut Pasteur, Unité de Chimie et Biocatalyse, CNRS UMR 3523, 75015 Paris, France</footnote>

<footnote><sup>e</sup>Normandie Univ, UNICAEN, CERMN, 14000 Caen, France</footnote>

<footnote><sup>f</sup>Université Paris-Est, Laboratoire de Santé Animale, ANSES, INRA, ENVA, UMR 1161 Virologie, 94700 Maisons-Alfort, France</footnote>

<footnote><sup>g</sup>ANSES, Laboratoire de pathologie équine de Dozulé, Unité de virologie et parasitologie équine, 14430 Dozulé, France</footnote>

<footnote><sup>h</sup>CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, F-69007, Lyon, France</footnote>

<footnote><sup>i</sup>Equipe Chimie et Biologie, Modélisation et Immunologie pour la Thérapie (CBMIT), Université Paris Descartes, CNRS UMR 8601, 75006 Paris, France</footnote>

<footnote>DOI of original article: 10.1016/j.antiviral.2020.104931</footnote>

<footnote>* Corresponding author.
E-mail address: erika.hue@laboratoire-labeo.fr (E. Hue).</footnote>
Keywords:

Real-time cell assay

Chemical library screening

Antiviral

Equid herpesvirus-1

This dataset includes compounds from three different libraries: i) 1,199 compounds from the Prestwick® Chemical Library, which contains mostly US Food and Drug Administration approved drugs (Prestwick® Chemical, Illkirch, France); ii) 1,651 compounds from the Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN, Caen, France); iii) 41 compounds (called herein in-house antiviral library) selected for their effects against different human viruses. Compounds effective against EHV-1 were selected using the area under normalised curves (AUCn) and the time required for the Cell Index to decrease by 50% after virus infection (CIT50). The full dataset from the screen is made publicly available for further analyses.

© 2020 The Authors. Published by Elsevier Inc.

This is an open access article under the CC BY license

(http://creativecommons.org/licenses/by/4.0/)

Specifications Table

Subject Virology, Biology

Specific subject area Antiviral compounds tested against equid herpesvirus-1

Type of data Table
Figure

Supplementary file (excel)

How data were acquired The antiviral screening dataset of compounds against equid herpesvirus-1 was acquired using impedance measurements with xCELLigence® RTCA MP system (ACEA Biosciences Inc., San Diego, CA, USA). Data were analysed with RTCA software 2.0 and Microsoft Excel (v. 2010, Microsoft Corporation, Washington, USA).

Data format Raw data: Microsoft Excel

Analysed data: Microsoft Excel

Analysed data: figure

Parameters for data collection Equine dermal fibroblasts were infected with the EHV-1 Kentucky D (KyD) strain (ATCC® VR700™) at a MOI of 0.01 and incubated at 37 °C and 5% CO2 in the presence of tested compounds. This study includes 2,891 compounds from three different libraries: i) 1,199 compounds from the Prestwick® Chemical Library, which contains mostly US Food and Drug Administration approved drugs (Prestwick Chemical, Illkirch, France); ii) 1,651 compounds from the Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN, Caen, France); iii) 41 compounds (called herein in-house antiviral library) selected for their effects against different human viruses. The screening by impedancemetry was performed on EHV-1 KyD-infected E. Derm cells as a model and using the RTCA MP system (ACEA Biosciences Inc.) as previously described by Thieulent et al., 2019 [2]. The area under normalised curves (AUCn) and the time required for the Cell Index to decrease by 50% after virus infection (CIT50) were analysed with RTCA software 2.0 and Microsoft Excel (v. 2010, Microsoft Corporation, Washington, USA).

Description of data collection All data collected originate from impedance measurements during antiviral assays against EHV-1 using the xCELLigence® RTCA MP system (ACEA Biosciences Inc). According to the manufacturer's recommendations, Cell index (CI) values were first normalised to match the last time point before cell infection using the RTCA software version 2.0 (ACEA Biosciences) prior to data analysis. Finally, four representative values were calculated for each culture conditions: area under normalised curves (AUCn; [3]),% AUC compared to control cells, time required for the CI to decrease by 50% after virus infection (CIT50; [4]) and Delta CIT50. The quality of the screening in 96-well format was assessed using the Z-factor calculation ([5]) based on AUCn values between 0 and 120 h post-infection (hpi).

(continued on next page)
Data source location
Institution: LABÉO, Normandie Univ, UNICAEN, BIOTARGEN EA7450,
ImpedanCELL

City/Town/Region: Saint-Contest

Country: France

Latitude and longitude (and GPS coordinates, if possible) for collected
samples/data: 49.201981, -0.395943

Data accessibility

The dataset is available with this article.

Related research article

C. Thieulent, E. Hue, G. Sutton, C. Fortier, P. Dallemagne, S. Zientara, H.

Munier-Lehmann, A. Hans, R. Paillot, P-O. Vidalain, S. Pronost.

Identification of antiviral compounds against equid herpesvirus-1 using
real-time cell assay screening: efficacy of decitabine and valganciclovir alone
and in combination.

Antiviral research.

https://doi.org/10.1016/j.antiviral.2020.104931.

## Value of the Data

* The dataset describes the antiviral activity of 2,891 compounds against equid herpesvirus-1 (EHV-1) and completes the limited number of active molecules previously described.

* These data would help research of antiviral compounds, especially against herpesviruses.

* These data may influence the development or the repositioning of compounds against herpesviruses.

* This method of medium/high-throughput screening and analysis can be adapted to identify antiviral compounds effective against multiple other viruses.

* The dataset is related to an equid herpesvirus but could be informative to viruses infecting other animal species, including humans, as part of the One-Health concept.

## 1. Data Description

Results from the screen with RTCA system are presented in Tables 1, 2 and 3. For each compound, we provide the area under normalised Cell Index curve from 0 to 96 hpi (AUCn), the%AUC compared to AUC of untreated, EHV-1-infected control wells, the time required for the cell index to decrease by 50 % after virus infection (CIT50) and the ΔCIT50 value obtained by comparing results for treated vs untreated, EHV-1-infected control wells. The Z'-factor reflects the quality of the screening in 96-well format. Table 1 shows the values obtained with the 1,199 compounds from the Prestwick® Chemical Library, containing mostly US Food and Drug Administration approved drugs (Prestwick Chemical, Illkirch, France). Raw data for the Prestwick® Chemical Library are presented in Supplementary File 1. Table 2 shows the values obtained with the 1,651 compounds from the Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN, Caen, France). Raw data for the CERMN Library are presented in Supplementary File 2. Table 3 shows the values obtained with the 41 compounds (called herein in-house antiviral library) selected for their effects against different human viruses. Raw data for the in-house antiviral library are presented in Supplementary File 3. Data shown in Fig. 1 correspond to%AUC and ΔCIT50 values for individual compounds from each library.

## 2. Experimental Design, Materials and Methods

### 1 Cell line and EHV-1 strain

Equine dermal fibroblasts (E. Derm, NBL-6 ATCC® CCL-57, Manassas, VA) were cultivated in Eagle's Minimum Essential Medium (EMEM; ATCC®) supplemented with 10 % foetal
<caption>**Table 1**</caption>

Screening of 1,199 compounds from the Prestwick® Chemical Library (Prestwick Chemical, Illkirch, France) at 10µg/mL. For each compound, the following values are provided: the area under normalised Cell Index curve (AUCn), the %AUCn compared to AUCn of untreated infected cells, the time required for the cell index to decrease by 50 % after virus infection (CIT50) and the ΔCIT50 value obtained by comparing results for treated vs untreated, EHV-1-infected control wells. The Z-factor was used to assess the quality of the screening in 96-well format. For untreated mock-infected and untreated infected cells, the mean ± SD of AUCn is reported. N.D., not determinable.

<table><thead><tr><th>Compound code</th><th>Z-factor</th><th>AUCn</th><th>%AUCn</th><th>CIT50</th><th>ΔCIT50</th></tr></thead><tbody><tr><td>P01 untreated mock-infected cells</td><td>0.55</td><td>224,80 ± 22,76</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P01 untreated infected cells</td><td>0.55</td><td>55,76 ± 2,46</td><td>N.D.</td><td>46:07:49</td><td>N.D.</td></tr><tr><td>P01A02</td><td>0.55</td><td>51.06</td><td>-8.41</td><td>44:04:18</td><td>-2.06</td></tr><tr><td>P01B02</td><td>0.55</td><td>79.62</td><td>42.80</td><td>51:28:21</td><td>5.34</td></tr><tr><td>P01C02</td><td>0.55</td><td>56.79</td><td>1.86</td><td>45:10:49</td><td>-0.95</td></tr><tr><td>P01D02</td><td>0.55</td><td>70.74</td><td>26.88</td><td>50:33:38</td><td>4.43</td></tr><tr><td>P01E02</td><td>0.55</td><td>68.24</td><td>22.39</td><td>44:54:22</td><td>-1.22</td></tr><tr><td>P01F02</td><td>0.55</td><td>70.62</td><td>26.66</td><td>56:06:02</td><td>9.97</td></tr><tr><td>P01G02</td><td>0.55</td><td>80.60</td><td>44.56</td><td>51:42:43</td><td>5.58</td></tr><tr><td>P01H02</td><td>0.55</td><td>73.27</td><td>31.41</td><td>47:53:08</td><td>1.76</td></tr><tr><td>P01A03</td><td>0.55</td><td>83.56</td><td>49.87</td><td>50:33:38</td><td>4.43</td></tr><tr><td>P01B03</td><td>0.55</td><td>73.60</td><td>32.00</td><td>51:00:11</td><td>4.87</td></tr><tr><td>P01C03</td><td>0.55</td><td>81.38</td><td>45.95</td><td>57:35:17</td><td>11.46</td></tr><tr><td>P01D03</td><td>0.55</td><td>64.97</td><td>16.52</td><td>48:21:33</td><td>2.23</td></tr><tr><td>P01E03</td><td>0.55</td><td>65.93</td><td>18.26</td><td>46:46:10</td><td>0.64</td></tr><tr><td>P01F03</td><td>0.55</td><td>53.17</td><td>-4.65</td><td>47:17:41</td><td>1.16</td></tr><tr><td>P01G03</td><td>0.55</td><td>78.27</td><td>40.37</td><td>51:14:10</td><td>5.11</td></tr><tr><td>P01H03</td><td>0.55</td><td>74.58</td><td>33.76</td><td>50:39:34</td><td>4.53</td></tr><tr><td>P01A04</td><td>0.55</td><td>90.10</td><td>61.60</td><td>49:08:43</td><td>3.01</td></tr><tr><td>P01B04</td><td>0.55</td><td>72.59</td><td>30.20</td><td>50:27:16</td><td>4.32</td></tr><tr><td>P01C04</td><td>0.55</td><td>85.75</td><td>53.80</td><td>59:13:28</td><td>13.09</td></tr><tr><td>P01D04</td><td>0.55</td><td>93.30</td><td>67.34</td><td>61:46:15</td><td>15.64</td></tr><tr><td>P01E04</td><td>0.55</td><td>52.51</td><td>-5.81</td><td>45:45:07</td><td>-0.38</td></tr><tr><td>P01F04</td><td>0.55</td><td>78.29</td><td>40.42</td><td>57:03:22</td><td>10.93</td></tr><tr><td>P01G04</td><td>0.55</td><td>77.35</td><td>38.73</td><td>47:36:32</td><td>1.48</td></tr><tr><td>P01H04</td><td>0.55</td><td>85.19</td><td>52.79</td><td>52:14:28</td><td>6.11</td></tr><tr><td>P01A05</td><td>0.55</td><td>104.46</td><td>87.35</td><td>55:40:41</td><td>9.55</td></tr><tr><td>P01B05</td><td>0.55</td><td>66.46</td><td>19.21</td><td>48:26:47</td><td>2.32</td></tr><tr><td>P01C05</td><td>0.55</td><td>60.73</td><td>8.93</td><td>44:06:15</td><td>-2.03</td></tr><tr><td>P01D05</td><td>0.55</td><td>66.69</td><td>19.61</td><td>48:24:48</td><td>2.28</td></tr><tr><td>P01E05</td><td>0.55</td><td>67.40</td><td>20.89</td><td>47:44:15</td><td>1.61</td></tr><tr><td>P01F05</td><td>0.55</td><td>59.57</td><td>6.85</td><td>47:17:24</td><td>1.16</td></tr><tr><td>P01G05</td><td>0.55</td><td>65.27</td><td>17.07</td><td>51:28:23</td><td>5.34</td></tr><tr><td>P01H05</td><td>0.55</td><td>69.43</td><td>24.53</td><td>53:52:57</td><td>7.75</td></tr><tr><td>P01A06</td><td>0.55</td><td>56.35</td><td>1.07</td><td>46:25:25</td><td>0.29</td></tr><tr><td>P01B06</td><td>0.55</td><td>66.45</td><td>19.17</td><td>48:21:40</td><td>2.23</td></tr><tr><td>P01C06</td><td>0.55</td><td>62.35</td><td>11.83</td><td>48:22:10</td><td>2.24</td></tr><tr><td>P01D06</td><td>0.55</td><td>64.67</td><td>15.98</td><td>49:56:56</td><td>3.82</td></tr><tr><td>P01E06</td><td>0.55</td><td>66.40</td><td>19.09</td><td>49:56:56</td><td>3.82</td></tr><tr><td>P01F06</td><td>0.55</td><td>72.34</td><td>29.75</td><td>49:00:18</td><td>2.87</td></tr><tr><td>P01G06</td><td>0.55</td><td>65.86</td><td>18.13</td><td>47:36:31</td><td>1.48</td></tr><tr><td>P01H06</td><td>0.55</td><td>102.80</td><td>84.38</td><td>53:20:54</td><td>7.22</td></tr><tr><td>P01A07</td><td>0.55</td><td>81.72</td><td>46.57</td><td>49:35:06</td><td>3.45</td></tr><tr><td>P01B07</td><td>0.55</td><td>75.27</td><td>34.99</td><td>52:02:02</td><td>5.90</td></tr><tr><td>P01C07</td><td>0.55</td><td>72.60</td><td>30.20</td><td>49:26:35</td><td>3.31</td></tr><tr><td>P01D07</td><td>0.55</td><td>57.34</td><td>2.85</td><td>47:15:10</td><td>1.12</td></tr><tr><td>P01E07</td><td>0.55</td><td>80.16</td><td>43.78</td><td>49:58:18</td><td>3.84</td></tr><tr><td>P01F07</td><td>0.55</td><td>82.86</td><td>48.61</td><td>53:22:54</td><td>7.25</td></tr><tr><td>P01G07</td><td>0.55</td><td>72.35</td><td>29.76</td><td>51:15:25</td><td>5.13</td></tr><tr><td>P01H07</td><td>0.55</td><td>90.93</td><td>63.08</td><td>61:49:31</td><td>15.70</td></tr><tr><td>P01A08</td><td>0.55</td><td>100.32</td><td>79.92</td><td>51:25:30</td><td>5.29</td></tr><tr><td>P01B08</td><td>0.55</td><td>60.05</td><td>7.71</td><td>45:05:39</td><td>-1.04</td></tr><tr><td>P01C08</td><td>0.55</td><td>58.73</td><td>5.34</td><td>49:15:27</td><td>3.13</td></tr><tr><td>P01D08</td><td>0.55</td><td>62.21</td><td>11.57</td><td>54:09:11</td><td>8.02</td></tr><tr><td>P01E08</td><td>0.55</td><td>56.71</td><td>1.72</td><td>46:50:16</td><td>0.71</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P01F08</td><td>0.55</td><td>74.97</td><td>34.45</td><td>50:08:25</td><td>4.01</td></tr><tr><td>P01G08</td><td>0.55</td><td>58.18</td><td>4.35</td><td>52:42:08</td><td>6.57</td></tr><tr><td>P01H08</td><td>0.55</td><td>97.29</td><td>74.50</td><td>51:42:07</td><td>5.57</td></tr><tr><td>P01A09</td><td>0.55</td><td>64.23</td><td>15.20</td><td>43:05:23</td><td>-3.04</td></tr><tr><td>P01B09</td><td>0.55</td><td>184.48</td><td>230.88</td><td>111:55:07</td><td>65.79</td></tr><tr><td>P01C09</td><td>0.55</td><td>56.08</td><td>0.58</td><td>48:24:42</td><td>2.28</td></tr><tr><td>P01D09</td><td>0.55</td><td>67.12</td><td>20.38</td><td>48:02:20</td><td>1.91</td></tr><tr><td>P01E09</td><td>0.55</td><td>71.85</td><td>28.87</td><td>52:06:29</td><td>5.98</td></tr><tr><td>P01F09</td><td>0.55</td><td>169.02</td><td>203.15</td><td>61:31:24</td><td>15.39</td></tr><tr><td>P01G09</td><td>0.55</td><td>107.87</td><td>93.48</td><td>61:57:29</td><td>15.83</td></tr><tr><td>P01H09</td><td>0.55</td><td>44.02</td><td>-21.05</td><td>53:25:41</td><td>7.30</td></tr><tr><td>P01A10</td><td>0.55</td><td>91.80</td><td>64.64</td><td>54:57:45</td><td>8.83</td></tr><tr><td>P01B10</td><td>0.55</td><td>67.73</td><td>21.48</td><td>43:59:03</td><td>-2.15</td></tr><tr><td>P01C10</td><td>0.55</td><td>58.92</td><td>5.68</td><td>45:04:39</td><td>-1.05</td></tr><tr><td>P01D10</td><td>0.55</td><td>50.25</td><td>-9.87</td><td>46:24:32</td><td>0.28</td></tr><tr><td>P01E10</td><td>0.55</td><td>61.00</td><td>9.41</td><td>44:35:20</td><td>-1.54</td></tr><tr><td>P01F10</td><td>0.55</td><td>57.20</td><td>2.60</td><td>47:36:42</td><td>1.48</td></tr><tr><td>P01G10</td><td>0.55</td><td>104.18</td><td>86.84</td><td>56:39:07</td><td>10.52</td></tr><tr><td>P01H10</td><td>0.55</td><td>74.09</td><td>32.88</td><td>44:18:07</td><td>-1.83</td></tr><tr><td>P01A11</td><td>0.55</td><td>92.00</td><td>65.01</td><td>49:57:59</td><td>3.84</td></tr><tr><td>P01B11</td><td>0.55</td><td>86.63</td><td>55.37</td><td>56:43:26</td><td>10.59</td></tr><tr><td>P01C11</td><td>0.55</td><td>67.86</td><td>21.71</td><td>51:26:20</td><td>5.31</td></tr><tr><td>P01D11</td><td>0.55</td><td>66.90</td><td>19.99</td><td>48:25:35</td><td>2.30</td></tr><tr><td>P01E11</td><td>0.55</td><td>62.26</td><td>11.66</td><td>46:25:09</td><td>0.29</td></tr><tr><td>P01F11</td><td>0.55</td><td>56.65</td><td>1.61</td><td>46:44:49</td><td>0.62</td></tr><tr><td>P01G11</td><td>0.55</td><td>60.43</td><td>8.37</td><td>47:09:36</td><td>1.03</td></tr><tr><td>P01H11</td><td>0.55</td><td>82.48</td><td>47.93</td><td>45:28:30</td><td>-0.66</td></tr><tr><td>P02 untreated mock-infected cells</td><td>0.60</td><td>173.87 ± 12.20</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P02 untreated infected cells</td><td>0.60</td><td>52.59 ± 3.87</td><td>N.D.</td><td>48:34:24</td><td>N.D.</td></tr><tr><td>P02A02</td><td>0.60</td><td>51.75</td><td>-1.61</td><td>40:35:35</td><td>-7.69</td></tr><tr><td>P02B02</td><td>0.60</td><td>63.87</td><td>21.44</td><td>45:55:37</td><td>-2.36</td></tr><tr><td>P02C02</td><td>0.60</td><td>84.03</td><td>59.77</td><td>60:04:32</td><td>11.79</td></tr><tr><td>P02D02</td><td>0.60</td><td>67.83</td><td>28.97</td><td>49:32:20</td><td>1.25</td></tr><tr><td>P02E02</td><td>0.60</td><td>53.63</td><td>1.96</td><td>41:34:55</td><td>-6.70</td></tr><tr><td>P02F02</td><td>0.60</td><td>56.17</td><td>6.79</td><td>44:18:50</td><td>-3.97</td></tr><tr><td>P02G02</td><td>0.60</td><td>64.75</td><td>23.11</td><td>47:24:24</td><td>-0.88</td></tr><tr><td>P02H02</td><td>0.60</td><td>54.53</td><td>3.69</td><td>44:01:16</td><td>-4.27</td></tr><tr><td>P02A03</td><td>0.60</td><td>55.67</td><td>5.86</td><td>49:32:20</td><td>1.25</td></tr><tr><td>P02B03</td><td>0.60</td><td>54.76</td><td>4.12</td><td>42:58:10</td><td>-5.32</td></tr><tr><td>P02C03</td><td>0.60</td><td>72.13</td><td>37.14</td><td>51:59:01</td><td>3.70</td></tr><tr><td>P02D03</td><td>0.60</td><td>60.44</td><td>14.92</td><td>44:57:24</td><td>-3.33</td></tr><tr><td>P02E03</td><td>0.60</td><td>74.57</td><td>41.79</td><td>44:40:49</td><td>-3.61</td></tr><tr><td>P02F03</td><td>0.60</td><td>53.45</td><td>1.63</td><td>45:39:07</td><td>-2.63</td></tr><tr><td>P02G03</td><td>0.60</td><td>55.53</td><td>5.58</td><td>42:55:37</td><td>-5.36</td></tr><tr><td>P02H03</td><td>0.60</td><td>54.43</td><td>3.48</td><td>42:02:18</td><td>-6.25</td></tr><tr><td>P02A04</td><td>0.60</td><td>54.65</td><td>3.91</td><td>45:56:41</td><td>-2.34</td></tr><tr><td>P02B04</td><td>0.60</td><td>53.49</td><td>1.70</td><td>44:28:34</td><td>-3.81</td></tr><tr><td>P02C04</td><td>0.60</td><td>64.47</td><td>22.58</td><td>50:16:02</td><td>1.98</td></tr><tr><td>P02D04</td><td>0.60</td><td>67.30</td><td>27.96</td><td>46:01:14</td><td>-2.27</td></tr><tr><td>P02E04</td><td>0.60</td><td>55.27</td><td>5.09</td><td>44:20:08</td><td>-3.95</td></tr><tr><td>P02F04</td><td>0.60</td><td>66.38</td><td>26.21</td><td>46:55:07</td><td>-1.37</td></tr><tr><td>P02G04</td><td>0.60</td><td>61.12</td><td>16.21</td><td>34:29:20</td><td>-13.80</td></tr><tr><td>P02H04</td><td>0.60</td><td>53.38</td><td>1.50</td><td>44:28:55</td><td>-3.80</td></tr><tr><td>P02A05</td><td>0.60</td><td>56.15</td><td>6.76</td><td>43:03:15</td><td>-5.23</td></tr><tr><td>P02B05</td><td>0.60</td><td>43.76</td><td>-16.79</td><td>42:14:15</td><td>-6.05</td></tr><tr><td>P02C05</td><td>0.60</td><td>64.63</td><td>22.89</td><td>48:21:24</td><td>0.07</td></tr><tr><td>P02D05</td><td>0.60</td><td>65.78</td><td>25.07</td><td>47:14:20</td><td>-1.05</td></tr><tr><td>P02E05</td><td>0.60</td><td>41.27</td><td>-21.54</td><td>40:05:15</td><td>-8.20</td></tr><tr><td>P02F05</td><td>0.60</td><td>60.42</td><td>14.88</td><td>44:34:59</td><td>-3.70</td></tr><tr><td>P02G05</td><td>0.60</td><td>60.38</td><td>14.81</td><td>46:20:48</td><td>-1.94</td></tr><tr><td>P02H05</td><td>0.60</td><td>51.98</td><td>-1.16</td><td>40:27:08</td><td>-7.83</td></tr><tr><td>P02A06</td><td>0.60</td><td>73.65</td><td>40.03</td><td>51:51:41</td><td>3.57</td></tr><tr><td>P02B06</td><td>0.60</td><td>26.50</td><td>-49.61</td><td>N.D.</td><td>N.D.</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P02C06</td><td>0.60</td><td>57.12</td><td>8.60</td><td>46:53:45</td><td>-1.39</td></tr><tr><td>P02D06</td><td>0.60</td><td>53.89</td><td>2.46</td><td>46:54:44</td><td>-1.37</td></tr><tr><td>P02E06</td><td>0.60</td><td>54.38</td><td>3.40</td><td>46:54:44</td><td>-1.37</td></tr><tr><td>P02F06</td><td>0.60</td><td>54.56</td><td>3.74</td><td>41:20:07</td><td>-6.95</td></tr><tr><td>P02G06</td><td>0.60</td><td>59.24</td><td>12.63</td><td>43:54:06</td><td>-4.38</td></tr><tr><td>P02H06</td><td>0.60</td><td>40.82</td><td>-22.38</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P02A07</td><td>0.60</td><td>125.87</td><td>139.32</td><td>85:30:13</td><td>37.22</td></tr><tr><td>P02B07</td><td>0.60</td><td>68.78</td><td>30.78</td><td>46:45:55</td><td>-1.52</td></tr><tr><td>P02C07</td><td>0.60</td><td>83.12</td><td>58.04</td><td>51:21:11</td><td>3.07</td></tr><tr><td>P02D07</td><td>0.60</td><td>54.38</td><td>3.40</td><td>42:16:53</td><td>-6.01</td></tr><tr><td>P02E07</td><td>0.60</td><td>20.06</td><td>-61.85</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P02F07</td><td>0.60</td><td>20.94</td><td>-60.18</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P02G07</td><td>0.60</td><td>66.55</td><td>26.53</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P02H07</td><td>0.60</td><td>45.95</td><td>-12.64</td><td>41:46:54</td><td>-6.51</td></tr><tr><td>P02A08</td><td>0.60</td><td>76.50</td><td>45.45</td><td>45:52:50</td><td>-2.41</td></tr><tr><td>P02B08</td><td>0.60</td><td>41.26</td><td>-21.56</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P02C08</td><td>0.60</td><td>54.92</td><td>4.42</td><td>48:46:42</td><td>0.49</td></tr><tr><td>P02D08</td><td>0.60</td><td>48.08</td><td>-8.59</td><td>41:06:35</td><td>-7.18</td></tr><tr><td>P02E08</td><td>0.60</td><td>44.03</td><td>-16.28</td><td>43:15:18</td><td>-5.03</td></tr><tr><td>P02F08</td><td>0.60</td><td>51.67</td><td>-1.76</td><td>42:07:41</td><td>-6.16</td></tr><tr><td>P02G08</td><td>0.60</td><td>68.68</td><td>30.59</td><td>48:14:55</td><td>-0.04</td></tr><tr><td>P02H08</td><td>0.60</td><td>55.40</td><td>5.34</td><td>43:51:32</td><td>-4.43</td></tr><tr><td>P02A09</td><td>0.60</td><td>64.71</td><td>23.04</td><td>49:48:25</td><td>1.52</td></tr><tr><td>P02B09</td><td>0.60</td><td>51.78</td><td>-1.55</td><td>43:34:58</td><td>-4.70</td></tr><tr><td>P02C09</td><td>0.60</td><td>59.51</td><td>13.14</td><td>46:40:26</td><td>-1.61</td></tr><tr><td>P02D09</td><td>0.60</td><td>57.96</td><td>10.20</td><td>42:31:31</td><td>-5.76</td></tr><tr><td>P02E09</td><td>0.60</td><td>82.35</td><td>56.57</td><td>56:04:34</td><td>7.79</td></tr><tr><td>P02F09</td><td>0.60</td><td>55.36</td><td>5.26</td><td>43:55:01</td><td>-4.37</td></tr><tr><td>P02G09</td><td>0.60</td><td>58.35</td><td>10.93</td><td>47:06:52</td><td>-1.17</td></tr><tr><td>P02H09</td><td>0.60</td><td>50.26</td><td>-4.45</td><td>43:58:40</td><td>-4.31</td></tr><tr><td>P02A10</td><td>0.60</td><td>58.73</td><td>11.66</td><td>43:49:23</td><td>-4.46</td></tr><tr><td>P02B10</td><td>0.60</td><td>60.26</td><td>14.58</td><td>52:25:59</td><td>4.15</td></tr><tr><td>P02C10</td><td>0.60</td><td>62.98</td><td>19.74</td><td>49:02:48</td><td>0.76</td></tr><tr><td>P02D10</td><td>0.60</td><td>62.34</td><td>18.54</td><td>44:10:00</td><td>-4.12</td></tr><tr><td>P02E10</td><td>0.60</td><td>44.96</td><td>-14.52</td><td>39:30:10</td><td>-8.78</td></tr><tr><td>P02F10</td><td>0.60</td><td>51.89</td><td>-1.35</td><td>41:34:17</td><td>-6.72</td></tr><tr><td>P02G10</td><td>0.60</td><td>59.70</td><td>13.51</td><td>46:25:06</td><td>-1.87</td></tr><tr><td>P02H10</td><td>0.60</td><td>56.58</td><td>7.58</td><td>45:09:27</td><td>-3.13</td></tr><tr><td>P02A11</td><td>0.60</td><td>61.98</td><td>17.84</td><td>44:32:31</td><td>-3.74</td></tr><tr><td>P02B11</td><td>0.60</td><td>58.32</td><td>10.89</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P02C11</td><td>0.60</td><td>58.03</td><td>10.33</td><td>48:56:56</td><td>0.66</td></tr><tr><td>P02D11</td><td>0.60</td><td>70.76</td><td>34.54</td><td>40:02:08</td><td>-8.25</td></tr><tr><td>P02E11</td><td>0.60</td><td>72.62</td><td>38.08</td><td>42:33:42</td><td>-5.72</td></tr><tr><td>P02F11</td><td>0.60</td><td>49.05</td><td>-6.74</td><td>41:02:32</td><td>-7.24</td></tr><tr><td>P02G11</td><td>0.60</td><td>63.53</td><td>20.79</td><td>47:43:15</td><td>-0.57</td></tr><tr><td>P02H11</td><td>0.60</td><td>55.01</td><td>4.60</td><td>47:23:07</td><td>-0.90</td></tr><tr><td>P03 untreated mock-infected cells</td><td>0.82</td><td>192.72 ± 4.32</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P03 untreated infected cells</td><td>0.82</td><td>56.35 ± 3.75</td><td>N.D.</td><td>40:23:40</td><td>N.D.</td></tr><tr><td>P03A02</td><td>0.82</td><td>71.76</td><td>27.34</td><td>46:52:04</td><td>6.47</td></tr><tr><td>P03B02</td><td>0.82</td><td>84.77</td><td>50.43</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P03C02</td><td>0.82</td><td>65.99</td><td>17.10</td><td>43:14:34</td><td>2.85</td></tr><tr><td>P03D02</td><td>0.82</td><td>33.83</td><td>-39.98</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P03E02</td><td>0.82</td><td>34.23</td><td>-39.26</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P03F02</td><td>0.82</td><td>68.31</td><td>21.22</td><td>43:19:17</td><td>2.93</td></tr><tr><td>P03G02</td><td>0.82</td><td>62.36</td><td>10.67</td><td>40:36:43</td><td>0.22</td></tr><tr><td>P03H02</td><td>0.82</td><td>78.89</td><td>40.00</td><td>46:01:37</td><td>5.63</td></tr><tr><td>P03A03</td><td>0.82</td><td>87.47</td><td>55.22</td><td>53:05:34</td><td>12.70</td></tr><tr><td>P03B03</td><td>0.82</td><td>81.81</td><td>45.17</td><td>44:48:22</td><td>4.41</td></tr><tr><td>P03C03</td><td>0.82</td><td>51.17</td><td>-9.20</td><td>38:21:52</td><td>-2.03</td></tr><tr><td>P03G03</td><td>0.82</td><td>66.57</td><td>18.14</td><td>44:49:52</td><td>4.44</td></tr><tr><td>P03E03</td><td>0.82</td><td>70.67</td><td>25.41</td><td>43:46:33</td><td>3.38</td></tr><tr><td>P03F03</td><td>0.82</td><td>55.86</td><td>-0.88</td><td>37:52:44</td><td>-2.52</td></tr><tr><td>P03G03</td><td>0.82</td><td>86.78</td><td>54.00</td><td>43:29:15</td><td>3.09</td></tr><tr><td>P03H03</td><td>0.82</td><td>84.38</td><td>49.74</td><td>46:22:54</td><td>5.99</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P03A04</td><td>0.82</td><td>53.55</td><td>-4.97</td><td>47:28:40</td><td>7.08</td></tr><tr><td>P03B04</td><td>0.82</td><td>67.88</td><td>20.45</td><td>44:01:53</td><td>3.64</td></tr><tr><td>P03C04</td><td>0.82</td><td>66.75</td><td>18.46</td><td>45:04:06</td><td>4.67</td></tr><tr><td>P03D04</td><td>0.82</td><td>60.86</td><td>7.99</td><td>40:58:43</td><td>0.58</td></tr><tr><td>P03E04</td><td>0.82</td><td>88.74</td><td>57.48</td><td>45:47:14</td><td>5.39</td></tr><tr><td>P03F04</td><td>0.82</td><td>71.55</td><td>26.98</td><td>44:13:42</td><td>3.83</td></tr><tr><td>P03G04</td><td>0.82</td><td>62.03</td><td>10.08</td><td>39:58:48</td><td>-0.41</td></tr><tr><td>P03H04</td><td>0.82</td><td>76.86</td><td>36.39</td><td>45:51:44</td><td>5.47</td></tr><tr><td>P03A05</td><td>0.82</td><td>64.48</td><td>14.42</td><td>45:29:41</td><td>5.10</td></tr><tr><td>P03B05</td><td>0.82</td><td>65.53</td><td>16.29</td><td>44:39:16</td><td>4.26</td></tr><tr><td>P03C05</td><td>0.82</td><td>28.52</td><td>-49.39</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P03D05</td><td>0.82</td><td>49.66</td><td>-11.87</td><td>36:51:47</td><td>-3.53</td></tr><tr><td>P03E05</td><td>0.82</td><td>82.76</td><td>46.87</td><td>44:25:41</td><td>4.03</td></tr><tr><td>P03F05</td><td>0.82</td><td>56.03</td><td>-0.57</td><td>39:53:23</td><td>-0.50</td></tr><tr><td>P03G05</td><td>0.82</td><td>81.04</td><td>43.81</td><td>42:35:20</td><td>2.19</td></tr><tr><td>P03H05</td><td>0.82</td><td>63.31</td><td>12.34</td><td>38:58:46</td><td>-1.42</td></tr><tr><td>P03A06</td><td>0.82</td><td>86.03</td><td>52.67</td><td>52:49:29</td><td>12.43</td></tr><tr><td>P03B06</td><td>0.82</td><td>48.53</td><td>-13.88</td><td>35:01:43</td><td>-5.37</td></tr><tr><td>P03C06</td><td>0.82</td><td>68.11</td><td>20.86</td><td>44:32:02</td><td>4.14</td></tr><tr><td>P03D06</td><td>0.82</td><td>56.49</td><td>0.24</td><td>41:13:49</td><td>0.84</td></tr><tr><td>P03E06</td><td>0.82</td><td>60.36</td><td>7.11</td><td>41:13:49</td><td>0.84</td></tr><tr><td>P03F06</td><td>0.82</td><td>78.57</td><td>39.42</td><td>45:32:18</td><td>5.14</td></tr><tr><td>P03G06</td><td>0.82</td><td>75.84</td><td>34.59</td><td>45:38:12</td><td>5.24</td></tr><tr><td>P03H06</td><td>0.82</td><td>99.48</td><td>76.52</td><td>54:50:08</td><td>14.44</td></tr><tr><td>P03A07</td><td>0.82</td><td>74.76</td><td>32.66</td><td>47:56:22</td><td>7.54</td></tr><tr><td>P03B07</td><td>0.82</td><td>83.36</td><td>47.93</td><td>46:49:49</td><td>6.44</td></tr><tr><td>P03C07</td><td>0.82</td><td>68.92</td><td>22.31</td><td>42:06:39</td><td>1.72</td></tr><tr><td>P03D07</td><td>0.82</td><td>52.02</td><td>-7.69</td><td>39:18:19</td><td>-1.09</td></tr><tr><td>P03E07</td><td>0.82</td><td>61.14</td><td>8.50</td><td>41:25:10</td><td>1.03</td></tr><tr><td>P03F07</td><td>0.82</td><td>63.78</td><td>13.18</td><td>44:08:56</td><td>3.75</td></tr><tr><td>P03G07</td><td>0.82</td><td>52.02</td><td>-7.69</td><td>41:36:54</td><td>1.22</td></tr><tr><td>P03H07</td><td>0.82</td><td>77.95</td><td>38.33</td><td>48:34:14</td><td>8.18</td></tr><tr><td>P03A08</td><td>0.82</td><td>66.96</td><td>18.82</td><td>45:02:41</td><td>4.65</td></tr><tr><td>P03B08</td><td>0.82</td><td>95.55</td><td>69.56</td><td>50:33:16</td><td>10.16</td></tr><tr><td>P03C08</td><td>0.82</td><td>77.89</td><td>38.23</td><td>45:13:30</td><td>4.83</td></tr><tr><td>P03D08</td><td>0.82</td><td>53.18</td><td>-5.63</td><td>38:38:40</td><td>-1.75</td></tr><tr><td>P03E08</td><td>0.82</td><td>121.07</td><td>114.85</td><td>50:41:49</td><td>10.30</td></tr><tr><td>P03F08</td><td>0.82</td><td>63.63</td><td>12.92</td><td>43:49:59</td><td>3.44</td></tr><tr><td>P03G08</td><td>0.82</td><td>88.27</td><td>56.64</td><td>48:33:48</td><td>8.17</td></tr><tr><td>P03H08</td><td>0.82</td><td>91.76</td><td>62.83</td><td>50:39:05</td><td>10.26</td></tr><tr><td>P03A09</td><td>0.82</td><td>83.83</td><td>48.75</td><td>52:09:11</td><td>11.76</td></tr><tr><td>P03B09</td><td>0.82</td><td>82.64</td><td>46.64</td><td>45:34:57</td><td>5.19</td></tr><tr><td>P03C09</td><td>0.82</td><td>60.95</td><td>8.16</td><td>41:50:14</td><td>1.44</td></tr><tr><td>P03D09</td><td>0.82</td><td>55.94</td><td>-0.73</td><td>37:37:32</td><td>-2.77</td></tr><tr><td>P03E09</td><td>0.82</td><td>71.44</td><td>26.77</td><td>41:10:52</td><td>0.79</td></tr><tr><td>P03F09</td><td>0.82</td><td>65.76</td><td>16.69</td><td>41:57:44</td><td>1.57</td></tr><tr><td>P03G09</td><td>0.82</td><td>71.49</td><td>26.85</td><td>42:27:33</td><td>2.06</td></tr><tr><td>P03H09</td><td>0.82</td><td>63.35</td><td>12.41</td><td>44:54:53</td><td>4.52</td></tr><tr><td>P03A10</td><td>0.82</td><td>66.95</td><td>18.80</td><td>46:22:50</td><td>5.99</td></tr><tr><td>P03B10</td><td>0.82</td><td>82.33</td><td>46.11</td><td>48:06:38</td><td>7.72</td></tr><tr><td>P03C10</td><td>0.82</td><td>63.73</td><td>13.08</td><td>40:48:06</td><td>0.41</td></tr><tr><td>P03D10</td><td>0.82</td><td>72.33</td><td>28.36</td><td>42:28:57</td><td>2.09</td></tr><tr><td>P03E10</td><td>0.82</td><td>63.27</td><td>12.27</td><td>39:18:48</td><td>-1.08</td></tr><tr><td>P03F10</td><td>0.82</td><td>64.37</td><td>14.23</td><td>39:05:55</td><td>-1.30</td></tr><tr><td>P03G10</td><td>0.82</td><td>75.08</td><td>33.23</td><td>41:59:42</td><td>1.60</td></tr><tr><td>P03H10</td><td>0.82</td><td>67.81</td><td>20.33</td><td>43:43:15</td><td>3.33</td></tr><tr><td>P03A11</td><td>0.82</td><td>61.19</td><td>8.59</td><td>45:20:36</td><td>4.95</td></tr><tr><td>P03B11</td><td>0.82</td><td>62.04</td><td>10.09</td><td>39:42:18</td><td>-0.69</td></tr><tr><td>P03C11</td><td>0.82</td><td>47.04</td><td>-16.53</td><td>36:10:19</td><td>-4.22</td></tr><tr><td>P03D11</td><td>0.82</td><td>63.05</td><td>11.88</td><td>42:13:16</td><td>1.83</td></tr><tr><td>P03E11</td><td>0.82</td><td>63.89</td><td>13.37</td><td>42:00:01</td><td>1.61</td></tr><tr><td>P03F11</td><td>0.82</td><td>52.47</td><td>-6.90</td><td>34:17:10</td><td>-6.11</td></tr><tr><td>P03G11</td><td>0.82</td><td>63.67</td><td>12.98</td><td>39:25:22</td><td>-0.97</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P03H11</td><td>0.82</td><td>82.02</td><td>45.56</td><td>46:43:20</td><td>6.33</td></tr><tr><td>P04 untreated mock-infected cells</td><td>0.85</td><td>197.50 ± 3.42</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P04 untreated infected cells</td><td>0.85</td><td>47.18 ± 3.94</td><td>N.D.</td><td>41:50:22</td><td>N.D.</td></tr><tr><td>P04A02</td><td>0.85</td><td>72.65</td><td>53.98</td><td>45:51:22</td><td>4.02</td></tr><tr><td>P04B02</td><td>0.85</td><td>55.98</td><td>18.66</td><td>37:48:05</td><td>-4.04</td></tr><tr><td>P04C02</td><td>0.85</td><td>54.79</td><td>16.13</td><td>39:37:44</td><td>-2.21</td></tr><tr><td>P04D02</td><td>0.85</td><td>61.37</td><td>30.07</td><td>40:57:52</td><td>-0.87</td></tr><tr><td>P04E02</td><td>0.85</td><td>67.17</td><td>42.37</td><td>40:19:34</td><td>-1.51</td></tr><tr><td>P04F02</td><td>0.85</td><td>61.90</td><td>31.20</td><td>38:47:03</td><td>-3.06</td></tr><tr><td>P04G02</td><td>0.85</td><td>79.73</td><td>69.00</td><td>43:10:36</td><td>1.34</td></tr><tr><td>P04H02</td><td>0.85</td><td>66.22</td><td>40.37</td><td>36:59:56</td><td>-4.84</td></tr><tr><td>P04A03</td><td>0.85</td><td>58.53</td><td>24.06</td><td>41:24:04</td><td>-0.44</td></tr><tr><td>P04B03</td><td>0.85</td><td>58.36</td><td>23.69</td><td>39:20:42</td><td>-2.49</td></tr><tr><td>P04C03</td><td>0.85</td><td>50.95</td><td>7.99</td><td>34:31:36</td><td>-7.37</td></tr><tr><td>P04D03</td><td>0.85</td><td>40.67</td><td>-13.79</td><td>54:00:36</td><td>12.17</td></tr><tr><td>P04E03</td><td>0.85</td><td>64.96</td><td>37.69</td><td>41:03:53</td><td>-0.77</td></tr><tr><td>P04F03</td><td>0.85</td><td>55.55</td><td>17.73</td><td>37:10:25</td><td>-4.67</td></tr><tr><td>P04G03</td><td>0.85</td><td>57.43</td><td>21.74</td><td>35:45:03</td><td>-6.09</td></tr><tr><td>P04H03</td><td>0.85</td><td>81.86</td><td>73.51</td><td>46:06:23</td><td>4.27</td></tr><tr><td>P04A04</td><td>0.85</td><td>41.50</td><td>-12.04</td><td>37:41:56</td><td>-4.14</td></tr><tr><td>P04B04</td><td>0.85</td><td>52.08</td><td>10.39</td><td>37:10:40</td><td>-4.66</td></tr><tr><td>P04C04</td><td>0.85</td><td>69.17</td><td>46.62</td><td>42:52:28</td><td>1.04</td></tr><tr><td>P04D04</td><td>0.85</td><td>58.11</td><td>23.18</td><td>40:35:12</td><td>-1.25</td></tr><tr><td>P04E04</td><td>0.85</td><td>72.34</td><td>53.32</td><td>47:20:21</td><td>5.50</td></tr><tr><td>P04F04</td><td>0.85</td><td>57.31</td><td>21.47</td><td>37:06:42</td><td>-4.73</td></tr><tr><td>P04G04</td><td>0.85</td><td>56.99</td><td>20.80</td><td>39:20:27</td><td>-2.50</td></tr><tr><td>P04H04</td><td>0.85</td><td>66.79</td><td>41.56</td><td>44:58:40</td><td>3.14</td></tr><tr><td>P04A05</td><td>0.85</td><td>60.17</td><td>27.53</td><td>39:10:46</td><td>-2.66</td></tr><tr><td>P04B05</td><td>0.85</td><td>58.53</td><td>24.06</td><td>37:19:05</td><td>-4.52</td></tr><tr><td>P04C05</td><td>0.85</td><td>46.68</td><td>-1.06</td><td>37:33:07</td><td>-4.29</td></tr><tr><td>P04D05</td><td>0.85</td><td>71.90</td><td>52.40</td><td>41:07:07</td><td>-0.72</td></tr><tr><td>P04E05</td><td>0.85</td><td>67.60</td><td>43.28</td><td>42:07:06</td><td>0.28</td></tr><tr><td>P04F05</td><td>0.85</td><td>60.52</td><td>28.29</td><td>39:08:18</td><td>-2.70</td></tr><tr><td>P04G05</td><td>0.85</td><td>48.17</td><td>2.11</td><td>35:18:35</td><td>-6.53</td></tr><tr><td>P04H05</td><td>0.85</td><td>64.12</td><td>35.91</td><td>39:57:08</td><td>-1.89</td></tr><tr><td>P04A06</td><td>0.85</td><td>61.05</td><td>29.41</td><td>41:01:08</td><td>-0.82</td></tr><tr><td>P04B06</td><td>0.85</td><td>49.68</td><td>5.30</td><td>37:12:18</td><td>-4.63</td></tr><tr><td>P04C06</td><td>0.85</td><td>51.36</td><td>8.86</td><td>35:22:20</td><td>-6.47</td></tr><tr><td>P04D06</td><td>0.85</td><td>60.48</td><td>28.20</td><td>39:28:04</td><td>-2.37</td></tr><tr><td>P04E06</td><td>0.85</td><td>58.53</td><td>24.06</td><td>39:28:04</td><td>-2.37</td></tr><tr><td>P04F06</td><td>0.85</td><td>70.50</td><td>49.44</td><td>42:43:53</td><td>0.89</td></tr><tr><td>P04G06</td><td>0.85</td><td>67.78</td><td>43.68</td><td>38:55:40</td><td>-2.91</td></tr><tr><td>P04H06</td><td>0.85</td><td>83.20</td><td>76.36</td><td>41:24:26</td><td>-0.43</td></tr><tr><td>P04A07</td><td>0.85</td><td>58.40</td><td>23.79</td><td>36:26:48</td><td>-5.39</td></tr><tr><td>P04B07</td><td>0.85</td><td>28.28</td><td>-40.05</td><td>43:01:02</td><td>1.18</td></tr><tr><td>P04C07</td><td>0.85</td><td>57.57</td><td>22.02</td><td>38:22:44</td><td>-3.46</td></tr><tr><td>P04D07</td><td>0.85</td><td>44.83</td><td>-4.98</td><td>33:21:03</td><td>-8.49</td></tr><tr><td>P04E07</td><td>0.85</td><td>6.97</td><td>-85.24</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P04F07</td><td>0.85</td><td>52.11</td><td>10.46</td><td>37:25:50</td><td>-4.41</td></tr><tr><td>P04G07</td><td>0.85</td><td>70.81</td><td>50.09</td><td>44:56:24</td><td>3.10</td></tr><tr><td>P04H07</td><td>0.85</td><td>55.17</td><td>16.93</td><td>38:00:20</td><td>-3.83</td></tr><tr><td>P04A08</td><td>0.85</td><td>31.91</td><td>-32.36</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P04B08</td><td>0.85</td><td>34.14</td><td>-27.64</td><td>48:19:21</td><td>6.48</td></tr><tr><td>P04C08</td><td>0.85</td><td>64.62</td><td>36.97</td><td>41:41:35</td><td>-0.15</td></tr><tr><td>P04D08</td><td>0.85</td><td>74.78</td><td>58.51</td><td>46:00:49</td><td>4.17</td></tr><tr><td>P04E08</td><td>0.85</td><td>79.63</td><td>68.79</td><td>45:01:24</td><td>3.18</td></tr><tr><td>P04F08</td><td>0.85</td><td>58.55</td><td>24.11</td><td>39:40:05</td><td>-2.17</td></tr><tr><td>P04G08</td><td>0.85</td><td>60.82</td><td>28.92</td><td>39:55:19</td><td>-1.92</td></tr><tr><td>P04H08</td><td>0.85</td><td>74.23</td><td>57.33</td><td>44:02:38</td><td>2.20</td></tr><tr><td>P04A09</td><td>0.85</td><td>72.88</td><td>54.47</td><td>40:43:22</td><td>-1.12</td></tr><tr><td>P04B09</td><td>0.85</td><td>61.12</td><td>29.54</td><td>42:15:24</td><td>0.42</td></tr><tr><td>P04C09</td><td>0.85</td><td>60.25</td><td>27.71</td><td>39:27:12</td><td>-2.39</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P04D09</td><td>0.85</td><td>52.48</td><td>11.24</td><td>36:10:08</td><td>-5.67</td></tr><tr><td>P04E09</td><td>0.85</td><td>54.47</td><td>15.46</td><td>38:33:47</td><td>-3.28</td></tr><tr><td>P04F09</td><td>0.85</td><td>45.83</td><td>-2.87</td><td>35:27:00</td><td>-6.39</td></tr><tr><td>P04G09</td><td>0.85</td><td>68.10</td><td>44.34</td><td>46:09:19</td><td>4.32</td></tr><tr><td>P04H09</td><td>0.85</td><td>23.09</td><td>-51.05</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P04A10</td><td>0.85</td><td>60.25</td><td>27.71</td><td>35:53:46</td><td>-5.94</td></tr><tr><td>P04B10</td><td>0.85</td><td>43.27</td><td>-8.29</td><td>33:10:47</td><td>-8.66</td></tr><tr><td>P04C10</td><td>0.85</td><td>65.58</td><td>39.00</td><td>42:59:24</td><td>1.15</td></tr><tr><td>P04D10</td><td>0.85</td><td>68.39</td><td>44.97</td><td>41:50:09</td><td>0.00</td></tr><tr><td>P04E10</td><td>0.85</td><td>51.18</td><td>8.48</td><td>34:49:08</td><td>-7.02</td></tr><tr><td>P04F10</td><td>0.85</td><td>41.40</td><td>-12.26</td><td>13:03:04</td><td>-28.79</td></tr><tr><td>P04G10</td><td>0.85</td><td>61.10</td><td>29.51</td><td>37:31:29</td><td>-4.31</td></tr><tr><td>P04H10</td><td>0.85</td><td>66.20</td><td>40.31</td><td>37:52:16</td><td>-3.97</td></tr><tr><td>P04A11</td><td>0.85</td><td>69.04</td><td>46.35</td><td>40:49:14</td><td>-1.02</td></tr><tr><td>P04B11</td><td>0.85</td><td>45.53</td><td>-3.50</td><td>34:26:01</td><td>-7.41</td></tr><tr><td>P04C11</td><td>0.85</td><td>47.52</td><td>0.73</td><td>42:53:06</td><td>1.05</td></tr><tr><td>P04D11</td><td>0.85</td><td>87.63</td><td>85.75</td><td>46:51:51</td><td>5.02</td></tr><tr><td>P04E11</td><td>0.85</td><td>48.78</td><td>3.39</td><td>35:54:20</td><td>-5.93</td></tr><tr><td>P04F11</td><td>0.85</td><td>51.77</td><td>9.73</td><td>37:30:33</td><td>-4.33</td></tr><tr><td>P04G11</td><td>0.85</td><td>59.04</td><td>25.13</td><td>38:52:16</td><td>-2.97</td></tr><tr><td>P04H11</td><td>0.85</td><td>76.57</td><td>62.29</td><td>44:05:15</td><td>2.25</td></tr><tr><td>P05 untreated mock-infected cells</td><td>0.68</td><td>215.55 ± 11.20</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P05 untreated infected cells</td><td>0.68</td><td>52.16 ± 6.37</td><td>N.D.</td><td>47:43:17</td><td>N.D.</td></tr><tr><td>P05A02</td><td>0.68</td><td>68.32</td><td>30.97</td><td>51:38:12</td><td>3.92</td></tr><tr><td>P05B02</td><td>0.68</td><td>56.50</td><td>8.32</td><td>52:57:55</td><td>5.24</td></tr><tr><td>P05C02</td><td>0.68</td><td>46.66</td><td>-10.55</td><td>46:50:38</td><td>-0.88</td></tr><tr><td>P05D02</td><td>0.68</td><td>54.93</td><td>5.30</td><td>49:20:40</td><td>1.62</td></tr><tr><td>P05E02</td><td>0.68</td><td>53.72</td><td>2.99</td><td>48:42:54</td><td>0.99</td></tr><tr><td>P05F02</td><td>0.68</td><td>58.27</td><td>11.71</td><td>50:42:54</td><td>2.99</td></tr><tr><td>P05G02</td><td>0.68</td><td>68.52</td><td>31.35</td><td>50:32:44</td><td>2.82</td></tr><tr><td>P05H02</td><td>0.68</td><td>105.56</td><td>102.36</td><td>56:31:05</td><td>8.80</td></tr><tr><td>P05A03</td><td>0.68</td><td>70.52</td><td>35.19</td><td>51:09:05</td><td>3.43</td></tr><tr><td>P05B03</td><td>0.68</td><td>73.86</td><td>41.59</td><td>52:51:35</td><td>5.14</td></tr><tr><td>P05C03</td><td>0.68</td><td>55.07</td><td>5.56</td><td>46:48:27</td><td>-0.91</td></tr><tr><td>P05D03</td><td>0.68</td><td>162.81</td><td>212.12</td><td>55:14:00</td><td>7.51</td></tr><tr><td>P05E03</td><td>0.68</td><td>98.43</td><td>88.70</td><td>46:36:54</td><td>-1.11</td></tr><tr><td>P05F03</td><td>0.68</td><td>72.88</td><td>39.72</td><td>50:13:00</td><td>2.50</td></tr><tr><td>P05G03</td><td>0.68</td><td>70.21</td><td>34.60</td><td>50:42:42</td><td>2.99</td></tr><tr><td>P05H03</td><td>0.68</td><td>72.43</td><td>38.86</td><td>50:25:41</td><td>2.71</td></tr><tr><td>P05A04</td><td>0.68</td><td>53.76</td><td>3.06</td><td>46:58:25</td><td>-0.75</td></tr><tr><td>P05B04</td><td>0.68</td><td>68.87</td><td>32.02</td><td>50:55:35</td><td>3.21</td></tr><tr><td>P05C04</td><td>0.68</td><td>62.65</td><td>20.11</td><td>52:04:12</td><td>4.35</td></tr><tr><td>P05D04</td><td>0.68</td><td>57.41</td><td>10.05</td><td>48:50:32</td><td>1.12</td></tr><tr><td>P05E04</td><td>0.68</td><td>40.68</td><td>-22.01</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P05F04</td><td>0.68</td><td>51.89</td><td>-0.53</td><td>46:39:16</td><td>-1.07</td></tr><tr><td>P05G04</td><td>0.68</td><td>79.85</td><td>53.07</td><td>54:52:55</td><td>7.16</td></tr><tr><td>P05H04</td><td>0.68</td><td>73.52</td><td>40.95</td><td>51:15:56</td><td>3.54</td></tr><tr><td>P05A05</td><td>0.68</td><td>63.71</td><td>22.14</td><td>44:07:41</td><td>-3.59</td></tr><tr><td>P05B05</td><td>0.68</td><td>52.69</td><td>1.01</td><td>47:04:52</td><td>-0.64</td></tr><tr><td>P05C05</td><td>0.68</td><td>51.40</td><td>-1.46</td><td>47:23:04</td><td>-0.34</td></tr><tr><td>P05D05</td><td>0.68</td><td>54.80</td><td>5.06</td><td>50:50:38</td><td>3.12</td></tr><tr><td>P05E05</td><td>0.68</td><td>43.92</td><td>-15.80</td><td>43:41:22</td><td>-4.03</td></tr><tr><td>P05F05</td><td>0.68</td><td>55.86</td><td>7.09</td><td>47:17:34</td><td>-0.43</td></tr><tr><td>P05G05</td><td>0.68</td><td>61.63</td><td>18.14</td><td>53:04:16</td><td>5.35</td></tr><tr><td>P05H05</td><td>0.68</td><td>56.36</td><td>8.04</td><td>50:42:35</td><td>2.99</td></tr><tr><td>P05A06</td><td>0.68</td><td>59.69</td><td>14.43</td><td>50:06:45</td><td>2.39</td></tr><tr><td>P05B06</td><td>0.68</td><td>45.10</td><td>-13.53</td><td>48:40:57</td><td>0.96</td></tr><tr><td>P05C06</td><td>0.68</td><td>71.31</td><td>36.70</td><td>51:29:58</td><td>3.78</td></tr><tr><td>P05D06</td><td>0.68</td><td>89.55</td><td>71.67</td><td>51:13:33</td><td>3.50</td></tr><tr><td>P05E06</td><td>0.68</td><td>24.36</td><td>-53.30</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P05F06</td><td>0.68</td><td>49.20</td><td>-5.69</td><td>50:52:28</td><td>3.15</td></tr><tr><td>P05G06</td><td>0.68</td><td>6.45</td><td>-87.64</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P05H06</td><td>0.68</td><td>64.90</td><td>24.41</td><td>48:24:47</td><td>0.69</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P05A07</td><td>0.68</td><td>67.19</td><td>28.80</td><td>51:21:57</td><td>3.64</td></tr><tr><td>P05B07</td><td>0.68</td><td>58.18</td><td>11.54</td><td>47:29:31</td><td>-0.23</td></tr><tr><td>P05C07</td><td>0.68</td><td>45.34</td><td>-13.07</td><td>46:33:14</td><td>-1.17</td></tr><tr><td>P05D07</td><td>0.68</td><td>57.27</td><td>9.79</td><td>51:35:40</td><td>3.87</td></tr><tr><td>P05E07</td><td>0.68</td><td>57.19</td><td>9.65</td><td>50:23:01</td><td>2.66</td></tr><tr><td>P05F07</td><td>0.68</td><td>59.93</td><td>14.89</td><td>51:38:59</td><td>3.93</td></tr><tr><td>P05G07</td><td>0.68</td><td>44.35</td><td>-14.97</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P05H07</td><td>0.68</td><td>47.89</td><td>-8.19</td><td>41:08:13</td><td>-6.58</td></tr><tr><td>P05A08</td><td>0.68</td><td>58.29</td><td>11.74</td><td>46:58:37</td><td>-0.74</td></tr><tr><td>P05B08</td><td>0.68</td><td>55.35</td><td>6.10</td><td>48:23:27</td><td>0.67</td></tr><tr><td>P05C08</td><td>0.68</td><td>43.25</td><td>-17.08</td><td>49:26:06</td><td>1.71</td></tr><tr><td>P05D08</td><td>0.68</td><td>54.34</td><td>4.17</td><td>51:19:22</td><td>3.60</td></tr><tr><td>P05E08</td><td>0.68</td><td>49.04</td><td>-6.00</td><td>50:21:05</td><td>2.63</td></tr><tr><td>P05F08</td><td>0.68</td><td>63.72</td><td>22.16</td><td>53:47:48</td><td>6.08</td></tr><tr><td>P05G08</td><td>0.68</td><td>80.68</td><td>54.66</td><td>60:05:45</td><td>12.37</td></tr><tr><td>P05H08</td><td>0.68</td><td>52.80</td><td>1.22</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P05A09</td><td>0.68</td><td>61.16</td><td>17.24</td><td>48:53:04</td><td>1.16</td></tr><tr><td>P05B09</td><td>0.68</td><td>75.90</td><td>45.50</td><td>48:38:40</td><td>0.92</td></tr><tr><td>P05C09</td><td>0.68</td><td>70.97</td><td>36.05</td><td>58:39:04</td><td>10.93</td></tr><tr><td>P05D09</td><td>0.68</td><td>66.99</td><td>28.42</td><td>52:32:29</td><td>4.82</td></tr><tr><td>P05E09</td><td>0.68</td><td>119.03</td><td>128.19</td><td>66:20:29</td><td>18.62</td></tr><tr><td>P05F09</td><td>0.68</td><td>47.40</td><td>-9.14</td><td>43:54:30</td><td>-3.81</td></tr><tr><td>P05G09</td><td>0.68</td><td>133.70</td><td>156.31</td><td>56:32:25</td><td>8.82</td></tr><tr><td>P05H09</td><td>0.68</td><td>58.62</td><td>12.39</td><td>46:24:37</td><td>-1.31</td></tr><tr><td>P05A10</td><td>0.68</td><td>55.78</td><td>6.93</td><td>46:10:57</td><td>-1.54</td></tr><tr><td>P05B10</td><td>0.68</td><td>67.02</td><td>28.48</td><td>51:06:03</td><td>3.38</td></tr><tr><td>P05C10</td><td>0.68</td><td>80.84</td><td>54.98</td><td>55:57:13</td><td>8.23</td></tr><tr><td>P05D10</td><td>0.68</td><td>53.06</td><td>1.73</td><td>50:21:55</td><td>2.64</td></tr><tr><td>P05E10</td><td>0.68</td><td>59.48</td><td>14.03</td><td>48:03:25</td><td>0.34</td></tr><tr><td>P05F10</td><td>0.68</td><td>55.96</td><td>7.28</td><td>48:13:33</td><td>0.50</td></tr><tr><td>P05G10</td><td>0.68</td><td>57.37</td><td>9.98</td><td>48:08:18</td><td>0.42</td></tr><tr><td>P05H10</td><td>0.68</td><td>72.34</td><td>38.68</td><td>58:16:44</td><td>10.56</td></tr><tr><td>P05A11</td><td>0.68</td><td>53.13</td><td>1.86</td><td>47:39:57</td><td>-0.06</td></tr><tr><td>P05B11</td><td>0.68</td><td>65.81</td><td>26.17</td><td>55:53:24</td><td>8.17</td></tr><tr><td>P05C11</td><td>0.68</td><td>56.79</td><td>8.88</td><td>51:08:45</td><td>3.42</td></tr><tr><td>P05D11</td><td>0.68</td><td>56.77</td><td>8.82</td><td>52:19:17</td><td>4.60</td></tr><tr><td>P05E11</td><td>0.68</td><td>44.19</td><td>-15.29</td><td>49:33:52</td><td>1.84</td></tr><tr><td>P05F11</td><td>0.68</td><td>70.24</td><td>34.65</td><td>54:52:24</td><td>7.15</td></tr><tr><td>P05G11</td><td>0.68</td><td>60.71</td><td>16.38</td><td>50:21:13</td><td>2.63</td></tr><tr><td>P05H11</td><td>0.68</td><td>61.53</td><td>17.96</td><td>51:09:37</td><td>3.44</td></tr><tr><td>P06 untreated mock-infected cells</td><td>0.71</td><td>182.91 ± 10.37</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P06 untreated infected cells</td><td>0.71</td><td>42.31 ± 3.33</td><td>N.D.</td><td>39:58:52</td><td>N.D.</td></tr><tr><td>P06A02</td><td>0.71</td><td>49.11</td><td>16.07</td><td>43:45:03</td><td>3.77</td></tr><tr><td>P06B02</td><td>0.71</td><td>51.26</td><td>21.15</td><td>43:18:17</td><td>3.32</td></tr><tr><td>P06C02</td><td>0.71</td><td>63.71</td><td>50.59</td><td>53:25:04</td><td>13.44</td></tr><tr><td>P06D02</td><td>0.71</td><td>57.68</td><td>36.34</td><td>46:10:47</td><td>6.20</td></tr><tr><td>P06E02</td><td>0.71</td><td>38.01</td><td>-10.16</td><td>14:20:30</td><td>-25.64</td></tr><tr><td>P06F02</td><td>0.71</td><td>55.53</td><td>31.26</td><td>47:00:29</td><td>7.03</td></tr><tr><td>P06G02</td><td>0.71</td><td>59.30</td><td>40.17</td><td>47:39:03</td><td>7.67</td></tr><tr><td>P06H02</td><td>0.71</td><td>47.40</td><td>12.04</td><td>38:03:37</td><td>-1.92</td></tr><tr><td>P06A03</td><td>0.71</td><td>58.68</td><td>38.69</td><td>44:50:06</td><td>4.85</td></tr><tr><td>P06B03</td><td>0.71</td><td>14.24</td><td>-66.34</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P06C03</td><td>0.71</td><td>52.77</td><td>24.73</td><td>44:56:50</td><td>4.97</td></tr><tr><td>P06D03</td><td>0.71</td><td>53.94</td><td>27.51</td><td>38:44:01</td><td>-1.25</td></tr><tr><td>P06E03</td><td>0.71</td><td>60.88</td><td>43.89</td><td>49:49:34</td><td>9.84</td></tr><tr><td>P06F03</td><td>0.71</td><td>54.23</td><td>28.19</td><td>47:52:04</td><td>7.89</td></tr><tr><td>P06G03</td><td>0.71</td><td>30.65</td><td>-27.56</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P06H03</td><td>0.71</td><td>51.52</td><td>21.78</td><td>45:43:41</td><td>5.75</td></tr><tr><td>P06A04</td><td>0.71</td><td>48.53</td><td>14.72</td><td>41:44:27</td><td>1.76</td></tr><tr><td>P06B04</td><td>0.71</td><td>46.61</td><td>10.18</td><td>42:18:14</td><td>2.32</td></tr><tr><td>P06C04</td><td>0.71</td><td>47.01</td><td>11.11</td><td>44:34:57</td><td>4.60</td></tr><tr><td>P06D04</td><td>0.71</td><td>55.35</td><td>30.83</td><td>49:43:13</td><td>9.74</td></tr><tr><td>P06E04</td><td>0.71</td><td>48.13</td><td>13.77</td><td>47:21:51</td><td>7.38</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P06F04</td><td>0.71</td><td>46.29</td><td>9.42</td><td>43:17:27</td><td>3.31</td></tr><tr><td>P06G04</td><td>0.71</td><td>60.09</td><td>42.04</td><td>51:46:59</td><td>11.80</td></tr><tr><td>P06H04</td><td>0.71</td><td>48.99</td><td>15.81</td><td>44:23:59</td><td>4.42</td></tr><tr><td>P06A05</td><td>0.71</td><td>54.96</td><td>29.90</td><td>47:21:32</td><td>7.38</td></tr><tr><td>P06B05</td><td>0.71</td><td>94.73</td><td>123.92</td><td>71:33:12</td><td>31.57</td></tr><tr><td>P06C05</td><td>0.71</td><td>80.54</td><td>90.38</td><td>51:58:37</td><td>12.00</td></tr><tr><td>P06D05</td><td>0.71</td><td>45.20</td><td>6.84</td><td>42:26:02</td><td>2.45</td></tr><tr><td>P06E05</td><td>0.71</td><td>51.18</td><td>20.98</td><td>45:59:27</td><td>6.01</td></tr><tr><td>P06F05</td><td>0.71</td><td>58.14</td><td>37.42</td><td>46:55:54</td><td>6.95</td></tr><tr><td>P06G05</td><td>0.71</td><td>49.01</td><td>15.85</td><td>42:57:44</td><td>2.98</td></tr><tr><td>P06H05</td><td>0.71</td><td>50.90</td><td>20.32</td><td>46:08:11</td><td>6.16</td></tr><tr><td>P06A06</td><td>0.71</td><td>38.22</td><td>-9.66</td><td>39:27:16</td><td>-0.53</td></tr><tr><td>P06B06</td><td>0.71</td><td>42.19</td><td>-0.27</td><td>43:44:15</td><td>3.76</td></tr><tr><td>P06C06</td><td>0.71</td><td>43.62</td><td>3.10</td><td>41:46:27</td><td>1.79</td></tr><tr><td>P06D06</td><td>0.71</td><td>43.59</td><td>3.02</td><td>40:53:52</td><td>0.92</td></tr><tr><td>P06E06</td><td>0.71</td><td>54.47</td><td>28.76</td><td>40:53:52</td><td>0.92</td></tr><tr><td>P06F06</td><td>0.71</td><td>50.40</td><td>19.12</td><td>46:45:58</td><td>6.79</td></tr><tr><td>P06G06</td><td>0.71</td><td>47.36</td><td>11.95</td><td>48:42:25</td><td>8.73</td></tr><tr><td>P06H06</td><td>0.71</td><td>44.68</td><td>5.60</td><td>43:31:37</td><td>3.55</td></tr><tr><td>P06A07</td><td>0.71</td><td>50.35</td><td>19.02</td><td>46:30:44</td><td>6.53</td></tr><tr><td>P06B07</td><td>0.71</td><td>48.21</td><td>13.95</td><td>43:54:37</td><td>3.93</td></tr><tr><td>P06C07</td><td>0.71</td><td>49.38</td><td>16.71</td><td>46:00:01</td><td>6.02</td></tr><tr><td>P06D07</td><td>0.71</td><td>31.01</td><td>-26.70</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P06E07</td><td>0.71</td><td>52.44</td><td>23.95</td><td>47:19:44</td><td>7.35</td></tr><tr><td>P06F07</td><td>0.71</td><td>53.65</td><td>26.80</td><td>44:24:38</td><td>4.43</td></tr><tr><td>P06G07</td><td>0.71</td><td>43.48</td><td>2.78</td><td>46:30:01</td><td>6.52</td></tr><tr><td>P06H07</td><td>0.71</td><td>29.32</td><td>-30.70</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P06A08</td><td>0.71</td><td>47.89</td><td>13.19</td><td>44:14:44</td><td>4.26</td></tr><tr><td>P06B08</td><td>0.71</td><td>49.88</td><td>17.90</td><td>46:13:16</td><td>6.24</td></tr><tr><td>P06C08</td><td>0.71</td><td>41.64</td><td>-1.57</td><td>46:15:28</td><td>6.28</td></tr><tr><td>P06D08</td><td>0.71</td><td>48.12</td><td>13.75</td><td>36:55:24</td><td>-3.06</td></tr><tr><td>P06E08</td><td>0.71</td><td>61.02</td><td>44.24</td><td>39:51:05</td><td>-0.13</td></tr><tr><td>P06F08</td><td>0.71</td><td>57.34</td><td>35.52</td><td>50:26:56</td><td>10.47</td></tr><tr><td>P06G08</td><td>0.71</td><td>50.18</td><td>18.61</td><td>46:50:11</td><td>6.86</td></tr><tr><td>P06H08</td><td>0.71</td><td>58.12</td><td>37.38</td><td>46:59:46</td><td>7.02</td></tr><tr><td>P06A09</td><td>0.71</td><td>51.18</td><td>20.98</td><td>44:16:48</td><td>4.30</td></tr><tr><td>P06B09</td><td>0.71</td><td>41.99</td><td>-0.74</td><td>43:00:17</td><td>3.02</td></tr><tr><td>P06C09</td><td>0.71</td><td>19.33</td><td>-54.31</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P06D09</td><td>0.71</td><td>18.13</td><td>-57.14</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P06E09</td><td>0.71</td><td>53.08</td><td>25.48</td><td>42:26:04</td><td>2.45</td></tr><tr><td>P06F09</td><td>0.71</td><td>47.10</td><td>11.33</td><td>42:34:19</td><td>2.59</td></tr><tr><td>P06G09</td><td>0.71</td><td>49.85</td><td>17.82</td><td>46:11:19</td><td>6.21</td></tr><tr><td>P06H09</td><td>0.71</td><td>39.36</td><td>-6.98</td><td>43:33:36</td><td>3.58</td></tr><tr><td>P06A10</td><td>0.71</td><td>84.39</td><td>99.48</td><td>74:23:49</td><td>34.42</td></tr><tr><td>P06B10</td><td>0.71</td><td>51.83</td><td>22.50</td><td>44:18:10</td><td>4.32</td></tr><tr><td>P06C10</td><td>0.71</td><td>43.00</td><td>1.64</td><td>43:08:58</td><td>3.17</td></tr><tr><td>P06D10</td><td>0.71</td><td>49.64</td><td>17.34</td><td>47:27:47</td><td>7.48</td></tr><tr><td>P06E10</td><td>0.71</td><td>55.90</td><td>32.14</td><td>47:38:38</td><td>7.66</td></tr><tr><td>P06F10</td><td>0.71</td><td>18.43</td><td>-56.44</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P06G10</td><td>0.71</td><td>48.55</td><td>14.76</td><td>44:24:41</td><td>4.43</td></tr><tr><td>P06H10</td><td>0.71</td><td>48.44</td><td>14.49</td><td>42:46:27</td><td>2.79</td></tr><tr><td>P06A11</td><td>0.71</td><td>45.25</td><td>6.96</td><td>43:00:13</td><td>3.02</td></tr><tr><td>P06B11</td><td>0.71</td><td>44.74</td><td>5.74</td><td>46:24:21</td><td>6.42</td></tr><tr><td>P06C11</td><td>0.71</td><td>53.55</td><td>26.59</td><td>49:18:44</td><td>9.33</td></tr><tr><td>P06D11</td><td>0.71</td><td>53.89</td><td>27.38</td><td>46:41:37</td><td>6.71</td></tr><tr><td>P06E11</td><td>0.71</td><td>52.38</td><td>23.81</td><td>46:29:19</td><td>6.51</td></tr><tr><td>P06F11</td><td>0.71</td><td>56.55</td><td>33.67</td><td>47:53:11</td><td>7.91</td></tr><tr><td>P06G11</td><td>0.71</td><td>41.65</td><td>-1.55</td><td>41:59:45</td><td>2.01</td></tr><tr><td>P06H11</td><td>0.71</td><td>8.63</td><td>-79.61</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P07 untreated</td><td>0.54</td><td>191.67 ± 5.99</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>mock-infected cells</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>P07 untreated infected cells</td><td>0.54</td><td>69.77 ± 12.53</td><td>N.D.</td><td>52:37:50</td><td>N.D.</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P07A02</td><td>0.54</td><td>55.35</td><td>-20.68</td><td>51:52:58</td><td>-0.75</td></tr><tr><td>P07B02</td><td>0.54</td><td>63.63</td><td>-8.81</td><td>51:58:26</td><td>-0.66</td></tr><tr><td>P07C02</td><td>0.54</td><td>70.07</td><td>0.43</td><td>50:08:19</td><td>-2.49</td></tr><tr><td>P07D02</td><td>0.54</td><td>107.71</td><td>54.36</td><td>56:28:23</td><td>3.84</td></tr><tr><td>P07E02</td><td>0.54</td><td>81.09</td><td>16.22</td><td>45:03:18</td><td>-7.58</td></tr><tr><td>P07F02</td><td>0.54</td><td>81.39</td><td>16.64</td><td>44:57:36</td><td>-7.67</td></tr><tr><td>P07G02</td><td>0.54</td><td>183.19</td><td>162.54</td><td>65:13:08</td><td>12.59</td></tr><tr><td>P07H02</td><td>0.54</td><td>73.48</td><td>5.31</td><td>49:42:58</td><td>-2.91</td></tr><tr><td>P07A03</td><td>0.54</td><td>62.11</td><td>-10.98</td><td>53:34:47</td><td>0.95</td></tr><tr><td>P07B03</td><td>0.54</td><td>99.13</td><td>42.07</td><td>46:48:12</td><td>-5.83</td></tr><tr><td>P07C03</td><td>0.54</td><td>83.09</td><td>19.08</td><td>45:24:08</td><td>-7.23</td></tr><tr><td>P07D03</td><td>0.54</td><td>72.73</td><td>4.24</td><td>51:45:19</td><td>-0.88</td></tr><tr><td>P07E03</td><td>0.54</td><td>79.68</td><td>14.19</td><td>43:51:48</td><td>-8.77</td></tr><tr><td>P07F03</td><td>0.54</td><td>74.09</td><td>6.18</td><td>51:49:41</td><td>-0.80</td></tr><tr><td>P07G03</td><td>0.54</td><td>67.21</td><td>-3.67</td><td>44:37:00</td><td>-8.01</td></tr><tr><td>P07H03</td><td>0.54</td><td>65.85</td><td>-5.63</td><td>43:50:33</td><td>-8.79</td></tr><tr><td>P07A04</td><td>0.54</td><td>61.80</td><td>-11.43</td><td>43:58:56</td><td>-8.65</td></tr><tr><td>P07B04</td><td>0.54</td><td>59.24</td><td>-15.10</td><td>47:22:04</td><td>-5.26</td></tr><tr><td>P07C04</td><td>0.54</td><td>57.85</td><td>-17.09</td><td>44:44:31</td><td>-7.89</td></tr><tr><td>P07D04</td><td>0.54</td><td>78.41</td><td>12.38</td><td>51:31:39</td><td>-1.10</td></tr><tr><td>P07E04</td><td>0.54</td><td>66.97</td><td>-4.02</td><td>46:19:06</td><td>-6.31</td></tr><tr><td>P07F04</td><td>0.54</td><td>58.73</td><td>-15.83</td><td>42:16:54</td><td>-10.35</td></tr><tr><td>P07G04</td><td>0.54</td><td>85.80</td><td>22.97</td><td>45:30:54</td><td>-7.12</td></tr><tr><td>P07H04</td><td>0.54</td><td>91.37</td><td>30.95</td><td>44:42:13</td><td>-7.93</td></tr><tr><td>P07A05</td><td>0.54</td><td>72.74</td><td>4.25</td><td>46:25:17</td><td>-6.21</td></tr><tr><td>P07B05</td><td>0.54</td><td>58.86</td><td>-15.65</td><td>47:43:05</td><td>-4.91</td></tr><tr><td>P07C05</td><td>0.54</td><td>69.20</td><td>-0.82</td><td>45:31:46</td><td>-7.10</td></tr><tr><td>P07D05</td><td>0.54</td><td>64.68</td><td>-7.30</td><td>52:00:11</td><td>-0.63</td></tr><tr><td>P07E05</td><td>0.54</td><td>48.76</td><td>-30.12</td><td>49:51:13</td><td>-2.78</td></tr><tr><td>P07F05</td><td>0.54</td><td>53.40</td><td>-23.47</td><td>42:11:58</td><td>-10.43</td></tr><tr><td>P07G05</td><td>0.54</td><td>87.25</td><td>25.04</td><td>47:52:43</td><td>-4.75</td></tr><tr><td>P07H05</td><td>0.54</td><td>76.63</td><td>9.82</td><td>46:16:36</td><td>-6.35</td></tr><tr><td>P07A06</td><td>0.54</td><td>75.90</td><td>8.78</td><td>53:36:46</td><td>0.98</td></tr><tr><td>P07B06</td><td>0.54</td><td>88.66</td><td>27.06</td><td>59:04:02</td><td>6.44</td></tr><tr><td>P07C06</td><td>0.54</td><td>95.48</td><td>36.83</td><td>60:54:00</td><td>8.27</td></tr><tr><td>P07D06</td><td>0.54</td><td>61.75</td><td>-11.50</td><td>49:14:44</td><td>-3.39</td></tr><tr><td>P07E06</td><td>0.54</td><td>60.82</td><td>-12.84</td><td>49:14:44</td><td>-3.39</td></tr><tr><td>P07F06</td><td>0.54</td><td>76.04</td><td>8.98</td><td>48:51:32</td><td>-3.77</td></tr><tr><td>P07G06</td><td>0.54</td><td>77.19</td><td>10.64</td><td>49:19:17</td><td>-3.31</td></tr><tr><td>P07H06</td><td>0.54</td><td>147.26</td><td>111.05</td><td>47:35:28</td><td>-5.04</td></tr><tr><td>P07A07</td><td>0.54</td><td>95.61</td><td>37.03</td><td>49:59:45</td><td>-2.63</td></tr><tr><td>P07B07</td><td>0.54</td><td>59.19</td><td>-15.17</td><td>42:45:14</td><td>-9.88</td></tr><tr><td>P07C07</td><td>0.54</td><td>57.82</td><td>-17.13</td><td>45:54:24</td><td>-6.72</td></tr><tr><td>P07D07</td><td>0.54</td><td>16.78</td><td>-75.94</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P07E07</td><td>0.54</td><td>72.21</td><td>3.49</td><td>49:03:54</td><td>-3.57</td></tr><tr><td>P07F07</td><td>0.54</td><td>68.99</td><td>-1.12</td><td>48:37:02</td><td>-4.01</td></tr><tr><td>P07G07</td><td>0.54</td><td>55.73</td><td>-20.13</td><td>40:14:57</td><td>-12.38</td></tr><tr><td>P07H07</td><td>0.54</td><td>21.15</td><td>-69.69</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P07A08</td><td>0.54</td><td>23.23</td><td>-66.71</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P07B08</td><td>0.54</td><td>68.36</td><td>-2.03</td><td>43:55:41</td><td>-8.70</td></tr><tr><td>P07C08</td><td>0.54</td><td>38.00</td><td>-45.54</td><td>39:23:08</td><td>-13.25</td></tr><tr><td>P07D08</td><td>0.54</td><td>59.11</td><td>-15.28</td><td>42:26:48</td><td>-10.18</td></tr><tr><td>P07E08</td><td>0.54</td><td>67.28</td><td>-3.58</td><td>48:53:59</td><td>-3.73</td></tr><tr><td>P07F08</td><td>0.54</td><td>66.44</td><td>-4.78</td><td>45:13:17</td><td>-7.41</td></tr><tr><td>P07G08</td><td>0.54</td><td>68.72</td><td>-1.51</td><td>46:29:14</td><td>-6.14</td></tr><tr><td>P07H08</td><td>0.54</td><td>62.98</td><td>-9.74</td><td>46:16:45</td><td>-6.35</td></tr><tr><td>P07A09</td><td>0.54</td><td>78.27</td><td>12.17</td><td>50:53:44</td><td>-1.74</td></tr><tr><td>P07B09</td><td>0.54</td><td>65.70</td><td>-5.85</td><td>44:34:09</td><td>-8.06</td></tr><tr><td>P07C09</td><td>0.54</td><td>63.48</td><td>-9.01</td><td>48:56:57</td><td>-3.68</td></tr><tr><td>P07D09</td><td>0.54</td><td>120.95</td><td>73.34</td><td>53:31:34</td><td>0.90</td></tr><tr><td>P07E09</td><td>0.54</td><td>59.37</td><td>-14.91</td><td>42:12:48</td><td>-10.42</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P07F09</td><td>0.54</td><td>75.92</td><td>8.81</td><td>46:29:49</td><td>-6.13</td></tr><tr><td>P07G09</td><td>0.54</td><td>71.68</td><td>2.73</td><td>50:11:53</td><td>-2.43</td></tr><tr><td>P07H09</td><td>0.54</td><td>78.02</td><td>11.82</td><td>45:09:03</td><td>-7.48</td></tr><tr><td>P07A10</td><td>0.54</td><td>33.49</td><td>-52.01</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P07B10</td><td>0.54</td><td>83.72</td><td>19.99</td><td>52:40:18</td><td>0.04</td></tr><tr><td>P07C10</td><td>0.54</td><td>59.43</td><td>-14.83</td><td>47:09:56</td><td>-5.47</td></tr><tr><td>P07D10</td><td>0.54</td><td>69.63</td><td>-0.21</td><td>49:18:10</td><td>-3.33</td></tr><tr><td>P07E10</td><td>0.54</td><td>74.78</td><td>7.18</td><td>46:38:29</td><td>-5.99</td></tr><tr><td>P07F10</td><td>0.54</td><td>74.52</td><td>6.80</td><td>45:07:57</td><td>-7.50</td></tr><tr><td>P07G10</td><td>0.54</td><td>66.58</td><td>-4.58</td><td>41:20:03</td><td>-11.30</td></tr><tr><td>P07H10</td><td>0.54</td><td>99.09</td><td>42.01</td><td>48:26:05</td><td>-4.20</td></tr><tr><td>P07A11</td><td>0.54</td><td>65.71</td><td>-5.82</td><td>50:50:04</td><td>-1.80</td></tr><tr><td>P07B11</td><td>0.54</td><td>74.74</td><td>7.12</td><td>49:53:25</td><td>-2.74</td></tr><tr><td>P07C11</td><td>0.54</td><td>61.29</td><td>-12.16</td><td>48:02:16</td><td>-4.59</td></tr><tr><td>P07D11</td><td>0.54</td><td>66.71</td><td>-4.39</td><td>44:26:40</td><td>-8.19</td></tr><tr><td>P07E11</td><td>0.54</td><td>73.24</td><td>4.97</td><td>46:13:06</td><td>-6.41</td></tr><tr><td>P07F11</td><td>0.54</td><td>68.54</td><td>-1.77</td><td>43:34:31</td><td>-9.06</td></tr><tr><td>P07G11</td><td>0.54</td><td>0.52</td><td>-99.26</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P07H11</td><td>0.54</td><td>86.23</td><td>23.59</td><td>46:42:36</td><td>-5.92</td></tr><tr><td>P08 untreated mock-infected cells</td><td>0.58</td><td>234.11 ± 18.80</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P08 untreated infected cells</td><td>0.58</td><td>60.66 ± 5.19</td><td>N.D.</td><td>43:40:48</td><td>N.D.</td></tr><tr><td>P08A02</td><td>0.58</td><td>66.36</td><td>9.39</td><td>42:27:39</td><td>-1.22</td></tr><tr><td>P08B02</td><td>0.58</td><td>82.87</td><td>36.62</td><td>49:28:11</td><td>5.79</td></tr><tr><td>P08C02</td><td>0.58</td><td>74.12</td><td>22.19</td><td>44:26:43</td><td>0.77</td></tr><tr><td>P08D02</td><td>0.58</td><td>77.71</td><td>28.12</td><td>46:14:25</td><td>2.56</td></tr><tr><td>P08E02</td><td>0.58</td><td>33.63</td><td>-44.55</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P08F02</td><td>0.58</td><td>46.34</td><td>-23.61</td><td>45:02:31</td><td>1.36</td></tr><tr><td>P08G02</td><td>0.58</td><td>71.54</td><td>17.93</td><td>46:28:49</td><td>2.80</td></tr><tr><td>P08H02</td><td>0.58</td><td>66.96</td><td>10.38</td><td>43:05:25</td><td>-0.59</td></tr><tr><td>P08A03</td><td>0.58</td><td>102.84</td><td>69.54</td><td>50:38:36</td><td>6.96</td></tr><tr><td>P08B03</td><td>0.58</td><td>143.03</td><td>135.80</td><td>41:09:40</td><td>-2.52</td></tr><tr><td>P08C03</td><td>0.58</td><td>132.33</td><td>118.16</td><td>46:02:12</td><td>2.36</td></tr><tr><td>P08D03</td><td>0.58</td><td>68.05</td><td>12.19</td><td>44:46:07</td><td>1.09</td></tr><tr><td>P08E03</td><td>0.58</td><td>77.45</td><td>27.68</td><td>49:43:17</td><td>6.04</td></tr><tr><td>P08F03</td><td>0.58</td><td>51.85</td><td>-14.53</td><td>45:47:55</td><td>2.12</td></tr><tr><td>P08G03</td><td>0.58</td><td>57.97</td><td>-4.44</td><td>38:56:27</td><td>-4.74</td></tr><tr><td>P08H03</td><td>0.58</td><td>69.85</td><td>15.15</td><td>41:09:37</td><td>-2.52</td></tr><tr><td>P08A04</td><td>0.58</td><td>89.58</td><td>47.68</td><td>44:51:34</td><td>1.18</td></tr><tr><td>P08B04</td><td>0.58</td><td>109.52</td><td>80.55</td><td>45:15:12</td><td>1.57</td></tr><tr><td>P08C04</td><td>0.58</td><td>101.25</td><td>66.93</td><td>39:46:21</td><td>-3.91</td></tr><tr><td>P08D04</td><td>0.58</td><td>90.81</td><td>49.71</td><td>49:51:18</td><td>6.17</td></tr><tr><td>P08E04</td><td>0.58</td><td>71.35</td><td>17.63</td><td>47:19:29</td><td>3.64</td></tr><tr><td>P08F04</td><td>0.58</td><td>68.35</td><td>12.68</td><td>66:56:20</td><td>23.26</td></tr><tr><td>P08G04</td><td>0.58</td><td>64.19</td><td>5.83</td><td>40:36:12</td><td>-3.08</td></tr><tr><td>P08H04</td><td>0.58</td><td>90.63</td><td>49.41</td><td>48:12:59</td><td>4.54</td></tr><tr><td>P08A05</td><td>0.58</td><td>101.31</td><td>67.01</td><td>48:23:24</td><td>4.71</td></tr><tr><td>P08B05</td><td>0.58</td><td>89.45</td><td>47.46</td><td>50:07:05</td><td>6.44</td></tr><tr><td>P08C05</td><td>0.58</td><td>93.64</td><td>54.37</td><td>50:04:00</td><td>6.39</td></tr><tr><td>P08D05</td><td>0.58</td><td>65.62</td><td>8.19</td><td>43:17:26</td><td>-0.39</td></tr><tr><td>P08E05</td><td>0.58</td><td>1.96</td><td>-96.76</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P08F05</td><td>0.58</td><td>12.21</td><td>-79.87</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P08G05</td><td>0.58</td><td>67.40</td><td>11.12</td><td>43:21:51</td><td>-0.32</td></tr><tr><td>P08H05</td><td>0.58</td><td>106.15</td><td>75.00</td><td>42:38:27</td><td>-1.04</td></tr><tr><td>P08A06</td><td>0.58</td><td>92.21</td><td>52.02</td><td>47:32:36</td><td>3.86</td></tr><tr><td>P08B06</td><td>0.58</td><td>70.57</td><td>16.34</td><td>48:49:49</td><td>5.15</td></tr><tr><td>P08C06</td><td>0.58</td><td>79.18</td><td>30.53</td><td>44:25:33</td><td>0.75</td></tr><tr><td>P08D06</td><td>0.58</td><td>62.82</td><td>3.57</td><td>48:31:41</td><td>4.85</td></tr><tr><td>P08E06</td><td>0.58</td><td>79.33</td><td>30.78</td><td>48:31:41</td><td>4.85</td></tr><tr><td>P08F06</td><td>0.58</td><td>97.87</td><td>61.35</td><td>48:29:26</td><td>4.81</td></tr><tr><td>P08G06</td><td>0.58</td><td>66.57</td><td>9.75</td><td>40:12:17</td><td>-3.48</td></tr><tr><td>P08H06</td><td>0.58</td><td>110.86</td><td>82.75</td><td>48:13:25</td><td>4.54</td></tr><tr><td>P08A07</td><td>0.58</td><td>95.77</td><td>57.88</td><td>44:47:49</td><td>1.12</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P08B07</td><td>0.58</td><td>91.94</td><td>51.56</td><td>45:40:24</td><td>1.99</td></tr><tr><td>P08C07</td><td>0.58</td><td>104.10</td><td>71.61</td><td>46:52:32</td><td>3.20</td></tr><tr><td>P08D07</td><td>0.58</td><td>71.44</td><td>17.77</td><td>48:13:38</td><td>4.55</td></tr><tr><td>P08E07</td><td>0.58</td><td>63.97</td><td>5.46</td><td>45:56:03</td><td>2.25</td></tr><tr><td>P08F07</td><td>0.58</td><td>106.48</td><td>75.54</td><td>55:17:19</td><td>11.61</td></tr><tr><td>P08G07</td><td>0.58</td><td>66.17</td><td>9.08</td><td>46:24:30</td><td>2.73</td></tr><tr><td>P08H07</td><td>0.58</td><td>96.28</td><td>58.72</td><td>45:38:47</td><td>1.97</td></tr><tr><td>P08A08</td><td>0.58</td><td>107.82</td><td>77.75</td><td>48:40:04</td><td>4.99</td></tr><tr><td>P08B08</td><td>0.58</td><td>104.22</td><td>71.81</td><td>45:33:29</td><td>1.88</td></tr><tr><td>P08C08</td><td>0.58</td><td>65.65</td><td>8.23</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P08D08</td><td>0.58</td><td>71.17</td><td>17.32</td><td>47:36:53</td><td>3.93</td></tr><tr><td>P08E08</td><td>0.58</td><td>63.01</td><td>3.88</td><td>44:30:37</td><td>0.83</td></tr><tr><td>P08F08</td><td>0.58</td><td>98.05</td><td>61.64</td><td>54:31:32</td><td>10.85</td></tr><tr><td>P08G08</td><td>0.58</td><td>70.61</td><td>16.40</td><td>44:12:06</td><td>0.52</td></tr><tr><td>P08H08</td><td>0.58</td><td>67.83</td><td>11.83</td><td>40:38:36</td><td>-3.04</td></tr><tr><td>P08A09</td><td>0.58</td><td>73.65</td><td>21.42</td><td>46:19:07</td><td>2.64</td></tr><tr><td>P08B09</td><td>0.58</td><td>70.26</td><td>15.82</td><td>45:26:15</td><td>1.76</td></tr><tr><td>P08C09</td><td>0.58</td><td>63.28</td><td>4.32</td><td>43:11:34</td><td>-0.49</td></tr><tr><td>P08D09</td><td>0.58</td><td>94.33</td><td>55.52</td><td>44:37:10</td><td>0.94</td></tr><tr><td>P08E09</td><td>0.58</td><td>61.69</td><td>1.70</td><td>47:14:19</td><td>3.56</td></tr><tr><td>P08F09</td><td>0.58</td><td>58.02</td><td>-4.35</td><td>42:08:50</td><td>-1.53</td></tr><tr><td>P08G09</td><td>0.58</td><td>100.35</td><td>65.44</td><td>41:27:24</td><td>-2.22</td></tr><tr><td>P08H09</td><td>0.58</td><td>84.20</td><td>38.81</td><td>48:36:15</td><td>4.92</td></tr><tr><td>P08A10</td><td>0.58</td><td>59.48</td><td>-1.94</td><td>49:14:08</td><td>5.56</td></tr><tr><td>P08B10</td><td>0.58</td><td>68.19</td><td>12.41</td><td>41:25:45</td><td>-2.25</td></tr><tr><td>P08C10</td><td>0.58</td><td>74.39</td><td>22.64</td><td>45:18:12</td><td>1.62</td></tr><tr><td>P08D10</td><td>0.58</td><td>56.73</td><td>-6.47</td><td>44:11:40</td><td>0.51</td></tr><tr><td>P08E10</td><td>0.58</td><td>62.00</td><td>2.22</td><td>37:59:18</td><td>-5.69</td></tr><tr><td>P08F10</td><td>0.58</td><td>73.11</td><td>20.53</td><td>48:47:17</td><td>5.11</td></tr><tr><td>P08G10</td><td>0.58</td><td>70.31</td><td>15.91</td><td>42:06:01</td><td>-1.58</td></tr><tr><td>P08H10</td><td>0.58</td><td>70.29</td><td>15.87</td><td>41:45:03</td><td>-1.93</td></tr><tr><td>P08A11</td><td>0.58</td><td>42.82</td><td>-29.41</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P08B11</td><td>0.58</td><td>80.97</td><td>33.49</td><td>53:53:55</td><td>10.22</td></tr><tr><td>P08C11</td><td>0.58</td><td>67.18</td><td>10.75</td><td>44:21:23</td><td>0.68</td></tr><tr><td>P08D11</td><td>0.58</td><td>99.74</td><td>64.43</td><td>47:53:25</td><td>4.21</td></tr><tr><td>P08E11</td><td>0.58</td><td>68.53</td><td>12.98</td><td>48:29:42</td><td>4.81</td></tr><tr><td>P08F11</td><td>0.58</td><td>63.90</td><td>5.34</td><td>45:05:08</td><td>1.41</td></tr><tr><td>P08G11</td><td>0.58</td><td>63.90</td><td>5.35</td><td>40:36:29</td><td>-3.07</td></tr><tr><td>P08H11</td><td>0.58</td><td>85.63</td><td>41.16</td><td>48:26:30</td><td>4.76</td></tr><tr><td>P09 untreated mock-infected cells</td><td>0.56</td><td>284.10 ± 27.03</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P09 untreated infected cells</td><td>0.56</td><td>61.25 ± 5.35</td><td>N.D.</td><td>46:25:57</td><td>N.D.</td></tr><tr><td>P09A02</td><td>0.56</td><td>76.21</td><td>24.43</td><td>48:02:41</td><td>1.61</td></tr><tr><td>P09B02</td><td>0.56</td><td>70.20</td><td>14.62</td><td>41:14:35</td><td>-5.19</td></tr><tr><td>P09C02</td><td>0.56</td><td>55.82</td><td>-8.86</td><td>45:02:13</td><td>-1.40</td></tr><tr><td>P09D02</td><td>0.56</td><td>51.61</td><td>-15.73</td><td>41:37:56</td><td>-4.80</td></tr><tr><td>P09E02</td><td>0.56</td><td>53.87</td><td>-12.05</td><td>44:42:44</td><td>-1.72</td></tr><tr><td>P09F02</td><td>0.56</td><td>57.59</td><td>-5.98</td><td>44:44:02</td><td>-1.70</td></tr><tr><td>P09G02</td><td>0.56</td><td>77.75</td><td>26.95</td><td>49:44:14</td><td>3.30</td></tr><tr><td>P09H02</td><td>0.56</td><td>65.51</td><td>6.95</td><td>41:25:29</td><td>-5.01</td></tr><tr><td>P09A03</td><td>0.56</td><td>41.78</td><td>-31.79</td><td>42:08:29</td><td>-4.29</td></tr><tr><td>P09B03</td><td>0.56</td><td>70.74</td><td>15.50</td><td>46:37:40</td><td>0.20</td></tr><tr><td>P09C03</td><td>0.56</td><td>70.86</td><td>15.69</td><td>46:43:11</td><td>0.29</td></tr><tr><td>P09D03</td><td>0.56</td><td>60.47</td><td>-1.27</td><td>48:27:00</td><td>2.02</td></tr><tr><td>P09E03</td><td>0.56</td><td>76.46</td><td>24.83</td><td>51:20:29</td><td>4.91</td></tr><tr><td>P09F03</td><td>0.56</td><td>84.60</td><td>38.12</td><td>52:17:48</td><td>5.86</td></tr><tr><td>P09G03</td><td>0.56</td><td>63.43</td><td>3.57</td><td>45:27:04</td><td>-0.98</td></tr><tr><td>P09H03</td><td>0.56</td><td>75.92</td><td>23.96</td><td>46:53:51</td><td>0.47</td></tr><tr><td>P09A04</td><td>0.56</td><td>47.24</td><td>-22.87</td><td>36:11:32</td><td>-10.24</td></tr><tr><td>P09B04</td><td>0.56</td><td>74.62</td><td>21.83</td><td>47:26:26</td><td>1.01</td></tr><tr><td>P09C04</td><td>0.56</td><td>59.54</td><td>-2.80</td><td>42:09:24</td><td>-4.28</td></tr><tr><td>P09D04</td><td>0.56</td><td>58.76</td><td>-4.06</td><td>42:48:22</td><td>-3.63</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P09E04</td><td>0.56</td><td>47.81</td><td>-21.94</td><td>42:38:31</td><td>-3.79</td></tr><tr><td>P09F04</td><td>0.56</td><td>64.35</td><td>5.07</td><td>47:05:17</td><td>0.66</td></tr><tr><td>P09G04</td><td>0.56</td><td>50.78</td><td>-17.10</td><td>41:12:13</td><td>-5.23</td></tr><tr><td>P09H04</td><td>0.56</td><td>47.55</td><td>-22.37</td><td>40:29:31</td><td>-5.94</td></tr><tr><td>P09A05</td><td>0.56</td><td>72.02</td><td>17.58</td><td>40:53:38</td><td>-5.54</td></tr><tr><td>P09B05</td><td>0.56</td><td>66.73</td><td>8.94</td><td>42:27:09</td><td>-3.98</td></tr><tr><td>P09C05</td><td>0.56</td><td>53.54</td><td>-12.59</td><td>42:14:47</td><td>-4.19</td></tr><tr><td>P09D05</td><td>0.56</td><td>57.27</td><td>-6.49</td><td>45:28:30</td><td>-0.96</td></tr><tr><td>P09E05</td><td>0.56</td><td>58.96</td><td>-3.74</td><td>46:16:15</td><td>-0.16</td></tr><tr><td>P09F05</td><td>0.56</td><td>48.58</td><td>-20.68</td><td>40:09:05</td><td>-6.28</td></tr><tr><td>P09G05</td><td>0.56</td><td>61.82</td><td>0.94</td><td>43:38:32</td><td>-2.79</td></tr><tr><td>P09H05</td><td>0.56</td><td>65.24</td><td>6.51</td><td>43:42:48</td><td>-2.72</td></tr><tr><td>P09A06</td><td>0.56</td><td>71.41</td><td>16.58</td><td>43:24:31</td><td>-3.02</td></tr><tr><td>P09B06</td><td>0.56</td><td>55.83</td><td>-8.84</td><td>44:03:17</td><td>-2.38</td></tr><tr><td>P09C06</td><td>0.56</td><td>54.89</td><td>-10.38</td><td>42:45:48</td><td>-3.67</td></tr><tr><td>P09D06</td><td>0.56</td><td>42.69</td><td>-30.31</td><td>47:23:08</td><td>0.95</td></tr><tr><td>P09E06</td><td>0.56</td><td>64.59</td><td>5.46</td><td>47:23:08</td><td>0.95</td></tr><tr><td>P09F06</td><td>0.56</td><td>50.94</td><td>-16.83</td><td>53:17:19</td><td>6.86</td></tr><tr><td>P09G06</td><td>0.56</td><td>14.63</td><td>-76.12</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P09H06</td><td>0.56</td><td>52.29</td><td>-14.62</td><td>43:35:09</td><td>-2.85</td></tr><tr><td>P09A07</td><td>0.56</td><td>20.51</td><td>-66.52</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P09B07</td><td>0.56</td><td>35.20</td><td>-42.54</td><td>31:28:58</td><td>-14.95</td></tr><tr><td>P09C07</td><td>0.56</td><td>48.88</td><td>-20.20</td><td>42:15:55</td><td>-4.17</td></tr><tr><td>P09D07</td><td>0.56</td><td>57.74</td><td>-5.73</td><td>44:54:46</td><td>-1.52</td></tr><tr><td>P09E07</td><td>0.56</td><td>39.26</td><td>-35.90</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P09F07</td><td>0.56</td><td>49.68</td><td>-18.89</td><td>43:09:30</td><td>-3.27</td></tr><tr><td>P09G07</td><td>0.56</td><td>64.27</td><td>4.93</td><td>49:00:41</td><td>2.58</td></tr><tr><td>P09H07</td><td>0.56</td><td>100.65</td><td>64.33</td><td>55:56:47</td><td>9.51</td></tr><tr><td>P09A08</td><td>0.56</td><td>53.17</td><td>-13.19</td><td>46:59:30</td><td>0.56</td></tr><tr><td>P09B08</td><td>0.56</td><td>70.94</td><td>15.83</td><td>40:13:25</td><td>-6.21</td></tr><tr><td>P09C08</td><td>0.56</td><td>57.53</td><td>-6.07</td><td>43:59:13</td><td>-2.45</td></tr><tr><td>P09D08</td><td>0.56</td><td>31.91</td><td>-47.91</td><td>34:35:33</td><td>-11.84</td></tr><tr><td>P09E08</td><td>0.56</td><td>62.18</td><td>1.52</td><td>48:16:47</td><td>1.85</td></tr><tr><td>P09F08</td><td>0.56</td><td>66.10</td><td>7.91</td><td>46:15:08</td><td>-0.18</td></tr><tr><td>P09G08</td><td>0.56</td><td>61.29</td><td>0.07</td><td>45:01:27</td><td>-1.41</td></tr><tr><td>P09H08</td><td>0.56</td><td>1.13</td><td>-98.16</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P09A09</td><td>0.56</td><td>55.72</td><td>-9.03</td><td>44:34:05</td><td>-1.86</td></tr><tr><td>P09B09</td><td>0.56</td><td>37.80</td><td>-38.28</td><td>38:17:08</td><td>-8.15</td></tr><tr><td>P09C09</td><td>0.56</td><td>34.48</td><td>-43.71</td><td>37:24:34</td><td>-9.02</td></tr><tr><td>P09D09</td><td>0.56</td><td>61.12</td><td>-0.21</td><td>43:57:20</td><td>-2.48</td></tr><tr><td>P09E09</td><td>0.56</td><td>44.92</td><td>-26.67</td><td>41:32:44</td><td>-4.89</td></tr><tr><td>P09F09</td><td>0.56</td><td>70.50</td><td>15.11</td><td>50:32:10</td><td>4.10</td></tr><tr><td>P09G09</td><td>0.56</td><td>24.31</td><td>-60.32</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P09H09</td><td>0.56</td><td>47.46</td><td>-22.51</td><td>38:29:29</td><td>-7.94</td></tr><tr><td>P09A10</td><td>0.56</td><td>57.05</td><td>-6.86</td><td>44:21:49</td><td>-2.07</td></tr><tr><td>P09B10</td><td>0.56</td><td>56.21</td><td>-8.23</td><td>45:03:48</td><td>-1.37</td></tr><tr><td>P09C10</td><td>0.56</td><td>78.00</td><td>27.34</td><td>47:21:08</td><td>0.92</td></tr><tr><td>P09D10</td><td>0.56</td><td>54.41</td><td>-11.16</td><td>40:45:55</td><td>-5.67</td></tr><tr><td>P09E10</td><td>0.56</td><td>64.28</td><td>4.95</td><td>50:09:37</td><td>3.73</td></tr><tr><td>P09F10</td><td>0.56</td><td>42.27</td><td>-30.98</td><td>45:37:22</td><td>-0.81</td></tr><tr><td>P09G10</td><td>0.56</td><td>52.00</td><td>-15.10</td><td>41:53:33</td><td>-4.54</td></tr><tr><td>P09H10</td><td>0.56</td><td>62.80</td><td>2.53</td><td>43:05:28</td><td>-3.34</td></tr><tr><td>P09A11</td><td>0.56</td><td>66.61</td><td>8.76</td><td>45:48:27</td><td>-0.62</td></tr><tr><td>P09B11</td><td>0.56</td><td>58.91</td><td>-3.83</td><td>40:31:39</td><td>-5.90</td></tr><tr><td>P09C11</td><td>0.56</td><td>53.00</td><td>-13.47</td><td>41:18:44</td><td>-5.12</td></tr><tr><td>P09D11</td><td>0.56</td><td>57.03</td><td>-6.89</td><td>42:20:13</td><td>-4.10</td></tr><tr><td>P09E11</td><td>0.56</td><td>47.85</td><td>-21.87</td><td>42:58:33</td><td>-3.46</td></tr><tr><td>P09F11</td><td>0.56</td><td>54.11</td><td>-11.66</td><td>44:29:00</td><td>-1.95</td></tr><tr><td>P09G11</td><td>0.56</td><td>38.71</td><td>-36.79</td><td>33:42:14</td><td>-12.73</td></tr><tr><td>P09H11</td><td>0.56</td><td>60.57</td><td>-1.11</td><td>42:58:10</td><td>-3.46</td></tr><tr><td>P10 untreated</td><td>0.59</td><td>294.24 ± 26.36</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>mock-infected cells</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>P10 untreated infected cells</td><td>0.59</td><td>50.08 ± 6.86</td><td>N.D.</td><td>46:19:34</td><td>N.D.</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P10A02</td><td>0.59</td><td>63.70</td><td>27.18</td><td>46:40:36</td><td>0.35</td></tr><tr><td>P10B02</td><td>0.59</td><td>69.06</td><td>37.88</td><td>46:21:30</td><td>0.03</td></tr><tr><td>P10C02</td><td>0.59</td><td>64.63</td><td>29.05</td><td>46:33:52</td><td>0.24</td></tr><tr><td>P10D02</td><td>0.59</td><td>65.26</td><td>30.30</td><td>44:09:07</td><td>-2.17</td></tr><tr><td>P10E02</td><td>0.59</td><td>45.74</td><td>-8.68</td><td>43:22:22</td><td>-2.95</td></tr><tr><td>P10F02</td><td>0.59</td><td>62.80</td><td>25.39</td><td>49:12:38</td><td>2.88</td></tr><tr><td>P10G02</td><td>0.59</td><td>38.66</td><td>-22.81</td><td>36:38:49</td><td>-9.68</td></tr><tr><td>P10H02</td><td>0.59</td><td>38.43</td><td>-23.27</td><td>39:23:10</td><td>-6.94</td></tr><tr><td>P10A03</td><td>0.59</td><td>39.35</td><td>-21.43</td><td>40:14:27</td><td>-6.09</td></tr><tr><td>P10B03</td><td>0.59</td><td>50.98</td><td>1.79</td><td>43:54:53</td><td>-2.41</td></tr><tr><td>P10C03</td><td>0.59</td><td>58.82</td><td>17.44</td><td>45:51:49</td><td>-0.46</td></tr><tr><td>P10D03</td><td>0.59</td><td>41.03</td><td>-18.08</td><td>44:01:30</td><td>-2.30</td></tr><tr><td>P10E03</td><td>0.59</td><td>46.59</td><td>-6.97</td><td>40:07:36</td><td>-6.20</td></tr><tr><td>P10F03</td><td>0.59</td><td>45.62</td><td>-8.91</td><td>42:36:07</td><td>-3.72</td></tr><tr><td>P10G03</td><td>0.59</td><td>8.14</td><td>-83.75</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P10H03</td><td>0.59</td><td>72.02</td><td>43.80</td><td>47:16:09</td><td>0.94</td></tr><tr><td>P10A04</td><td>0.59</td><td>45.57</td><td>-9.02</td><td>42:50:00</td><td>-3.49</td></tr><tr><td>P10B04</td><td>0.59</td><td>63.69</td><td>27.17</td><td>44:38:53</td><td>-1.68</td></tr><tr><td>P10C04</td><td>0.59</td><td>42.40</td><td>-15.35</td><td>38:07:01</td><td>-8.21</td></tr><tr><td>P10D04</td><td>0.59</td><td>79.21</td><td>58.16</td><td>47:40:19</td><td>1.35</td></tr><tr><td>P10E04</td><td>0.59</td><td>57.16</td><td>14.13</td><td>46:32:56</td><td>0.22</td></tr><tr><td>P10F04</td><td>0.59</td><td>62.86</td><td>25.51</td><td>44:51:49</td><td>-1.46</td></tr><tr><td>P10G04</td><td>0.59</td><td>76.78</td><td>53.31</td><td>45:33:46</td><td>-0.76</td></tr><tr><td>P10H04</td><td>0.59</td><td>64.88</td><td>29.55</td><td>51:21:53</td><td>5.04</td></tr><tr><td>P10A05</td><td>0.59</td><td>34.59</td><td>-30.93</td><td>36:20:54</td><td>-9.98</td></tr><tr><td>P10B05</td><td>0.59</td><td>36.83</td><td>-26.46</td><td>35:39:28</td><td>-10.67</td></tr><tr><td>P10C05</td><td>0.59</td><td>50.73</td><td>1.29</td><td>45:55:41</td><td>-0.40</td></tr><tr><td>P10D05</td><td>0.59</td><td>46.43</td><td>-7.29</td><td>45:21:08</td><td>-0.97</td></tr><tr><td>P10E05</td><td>0.59</td><td>56.05</td><td>11.91</td><td>43:43:18</td><td>-2.60</td></tr><tr><td>P10F05</td><td>0.59</td><td>44.86</td><td>-10.43</td><td>37:49:38</td><td>-8.50</td></tr><tr><td>P10G05</td><td>0.59</td><td>41.24</td><td>-17.66</td><td>38:23:30</td><td>-7.93</td></tr><tr><td>P10H05</td><td>0.59</td><td>60.77</td><td>21.33</td><td>44:52:48</td><td>-1.45</td></tr><tr><td>P10A06</td><td>0.59</td><td>48.38</td><td>-3.41</td><td>41:23:49</td><td>-4.93</td></tr><tr><td>P10B06</td><td>0.59</td><td>3.00</td><td>-94.02</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P10C06</td><td>0.59</td><td>53.68</td><td>7.18</td><td>41:32:53</td><td>-4.78</td></tr><tr><td>P10D06</td><td>0.59</td><td>44.40</td><td>-11.35</td><td>42:24:22</td><td>-3.92</td></tr><tr><td>P10E06</td><td>0.59</td><td>28.36</td><td>-43.38</td><td>42:24:22</td><td>-3.92</td></tr><tr><td>P10F06</td><td>0.59</td><td>37.12</td><td>-25.89</td><td>39:12:14</td><td>-7.12</td></tr><tr><td>P10G06</td><td>0.59</td><td>42.26</td><td>-15.63</td><td>37:33:41</td><td>-8.76</td></tr><tr><td>P10H06</td><td>0.59</td><td>0.65</td><td>-98.71</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P10A07</td><td>0.59</td><td>57.88</td><td>15.56</td><td>46:28:10</td><td>0.14</td></tr><tr><td>P10B07</td><td>0.59</td><td>53.58</td><td>6.98</td><td>42:26:01</td><td>-3.89</td></tr><tr><td>P10C07</td><td>0.59</td><td>1.67</td><td>-96.67</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P10D07</td><td>0.59</td><td>37.51</td><td>-25.11</td><td>47:11:47</td><td>0.87</td></tr><tr><td>P10E07</td><td>0.59</td><td>50.02</td><td>-0.13</td><td>41:24:03</td><td>-4.93</td></tr><tr><td>P10F07</td><td>0.59</td><td>42.16</td><td>-15.82</td><td>39:03:05</td><td>-7.27</td></tr><tr><td>P10G07</td><td>0.59</td><td>39.03</td><td>-22.07</td><td>41:47:24</td><td>-4.54</td></tr><tr><td>P10H07</td><td>0.59</td><td>59.39</td><td>18.58</td><td>47:04:07</td><td>0.74</td></tr><tr><td>P10A08</td><td>0.59</td><td>60.39</td><td>20.58</td><td>39:13:48</td><td>-7.10</td></tr><tr><td>P10B08</td><td>0.59</td><td>55.63</td><td>11.08</td><td>39:13:36</td><td>-7.10</td></tr><tr><td>P10C08</td><td>0.59</td><td>38.15</td><td>-23.83</td><td>38:19:04</td><td>-8.01</td></tr><tr><td>P10D08</td><td>0.59</td><td>60.53</td><td>20.85</td><td>43:24:28</td><td>-2.92</td></tr><tr><td>P10E08</td><td>0.59</td><td>52.32</td><td>4.47</td><td>43:27:48</td><td>-2.86</td></tr><tr><td>P10F08</td><td>0.59</td><td>158.99</td><td>217.45</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P10G08</td><td>0.59</td><td>43.88</td><td>-12.40</td><td>41:50:06</td><td>-4.49</td></tr><tr><td>P10H08</td><td>0.59</td><td>48.96</td><td>-2.25</td><td>47:05:25</td><td>0.76</td></tr><tr><td>P10A09</td><td>0.59</td><td>56.97</td><td>13.74</td><td>45:46:27</td><td>-0.55</td></tr><tr><td>P10B09</td><td>0.59</td><td>62.12</td><td>24.03</td><td>44:03:11</td><td>-2.27</td></tr><tr><td>P10C09</td><td>0.59</td><td>59.96</td><td>19.72</td><td>71:51:03</td><td>25.52</td></tr><tr><td>P10D09</td><td>0.59</td><td>58.25</td><td>16.32</td><td>47:13:31</td><td>0.90</td></tr><tr><td>P10E09</td><td>0.59</td><td>121.16</td><td>141.92</td><td>75:20:35</td><td>29.02</td></tr><tr><td>P10F09</td><td>0.59</td><td>66.87</td><td>33.52</td><td>52:51:43</td><td>6.54</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P10G09</td><td>0.59</td><td>43.44</td><td>-13.27</td><td>36:00:49</td><td>-10.31</td></tr><tr><td>P10H09</td><td>0.59</td><td>43.74</td><td>-12.67</td><td>45:05:30</td><td>-1.23</td></tr><tr><td>P10A10</td><td>0.59</td><td>54.96</td><td>9.73</td><td>43:19:28</td><td>-3.00</td></tr><tr><td>P10B10</td><td>0.59</td><td>119.98</td><td>139.55</td><td>52:49:34</td><td>6.50</td></tr><tr><td>P10C10</td><td>0.59</td><td>71.39</td><td>42.54</td><td>49:30:54</td><td>3.19</td></tr><tr><td>P10D10</td><td>0.59</td><td>55.88</td><td>11.58</td><td>46:36:10</td><td>0.28</td></tr><tr><td>P10E10</td><td>0.59</td><td>48.46</td><td>-3.25</td><td>40:53:46</td><td>-5.43</td></tr><tr><td>P10F10</td><td>0.59</td><td>57.13</td><td>14.07</td><td>43:28:01</td><td>-2.86</td></tr><tr><td>P10G10</td><td>0.59</td><td>69.29</td><td>38.34</td><td>48:21:55</td><td>2.04</td></tr><tr><td>P10H10</td><td>0.59</td><td>68.13</td><td>36.03</td><td>46:42:18</td><td>0.38</td></tr><tr><td>P10A11</td><td>0.59</td><td>66.46</td><td>32.71</td><td>45:22:26</td><td>-0.95</td></tr><tr><td>P10B11</td><td>0.59</td><td>5.31</td><td>-89.40</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P10C11</td><td>0.59</td><td>49.86</td><td>-0.44</td><td>41:07:00</td><td>-5.21</td></tr><tr><td>P10D11</td><td>0.59</td><td>53.01</td><td>5.84</td><td>45:55:42</td><td>-0.40</td></tr><tr><td>P10E11</td><td>0.59</td><td>51.47</td><td>2.77</td><td>42:47:20</td><td>-3.54</td></tr><tr><td>P10F11</td><td>0.59</td><td>43.73</td><td>-12.68</td><td>43:21:50</td><td>-2.96</td></tr><tr><td>P10G11</td><td>0.59</td><td>23.71</td><td>-52.65</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P10H11</td><td>0.59</td><td>90.18</td><td>80.06</td><td>55:03:21</td><td>8.73</td></tr><tr><td>P11 untreated mock-infected cells</td><td>0.79</td><td>235.76 ± 9.34</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P11 untreated infected cells</td><td>0.79</td><td>53.01 ± 3.26</td><td>N.D.</td><td>42:13:36</td><td>N.D.</td></tr><tr><td>P11A02</td><td>0.79</td><td>64.21</td><td>21.12</td><td>46:16:25</td><td>4.05</td></tr><tr><td>P11B02</td><td>0.79</td><td>54.02</td><td>1.89</td><td>45:08:34</td><td>2.92</td></tr><tr><td>P11C02</td><td>0.79</td><td>54.50</td><td>2.80</td><td>42:01:55</td><td>-0.19</td></tr><tr><td>P11D02</td><td>0.79</td><td>61.01</td><td>15.08</td><td>45:55:24</td><td>3.70</td></tr><tr><td>P11E02</td><td>0.79</td><td>20.39</td><td>-61.54</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P11F02</td><td>0.79</td><td>47.39</td><td>-10.61</td><td>41:25:38</td><td>-0.80</td></tr><tr><td>P11G02</td><td>0.79</td><td>55.21</td><td>4.14</td><td>41:21:32</td><td>-0.87</td></tr><tr><td>P11H02</td><td>0.79</td><td>7.23</td><td>-86.35</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P11A03</td><td>0.79</td><td>64.21</td><td>21.12</td><td>42:43:22</td><td>0.50</td></tr><tr><td>P11B03</td><td>0.79</td><td>54.02</td><td>1.89</td><td>44:47:28</td><td>2.56</td></tr><tr><td>P11C03</td><td>0.79</td><td>54.50</td><td>2.80</td><td>41:04:50</td><td>-1.15</td></tr><tr><td>P11D03</td><td>0.79</td><td>61.01</td><td>15.08</td><td>42:23:44</td><td>0.17</td></tr><tr><td>P11E03</td><td>0.79</td><td>20.39</td><td>-61.54</td><td>51:15:05</td><td>9.02</td></tr><tr><td>P11F03</td><td>0.79</td><td>47.39</td><td>-10.61</td><td>46:04:55</td><td>3.86</td></tr><tr><td>P11G03</td><td>0.79</td><td>55.21</td><td>4.14</td><td>42:41:09</td><td>0.46</td></tr><tr><td>P11H03</td><td>0.79</td><td>7.23</td><td>-86.35</td><td>42:54:57</td><td>0.69</td></tr><tr><td>P11A04</td><td>0.79</td><td>58.41</td><td>10.17</td><td>42:55:17</td><td>0.69</td></tr><tr><td>P11B04</td><td>0.79</td><td>51.11</td><td>-3.59</td><td>42:20:48</td><td>0.12</td></tr><tr><td>P11C04</td><td>0.79</td><td>47.35</td><td>-10.68</td><td>42:02:35</td><td>-0.18</td></tr><tr><td>P11D04</td><td>0.79</td><td>55.42</td><td>4.55</td><td>46:03:40</td><td>3.83</td></tr><tr><td>P11E04</td><td>0.79</td><td>55.82</td><td>5.29</td><td>44:13:05</td><td>1.99</td></tr><tr><td>P11F04</td><td>0.79</td><td>56.64</td><td>6.84</td><td>39:42:13</td><td>-2.52</td></tr><tr><td>P11G04</td><td>0.79</td><td>58.65</td><td>10.64</td><td>44:03:24</td><td>1.83</td></tr><tr><td>P11H04</td><td>0.79</td><td>55.95</td><td>5.55</td><td>41:03:29</td><td>-1.17</td></tr><tr><td>P11A05</td><td>0.79</td><td>53.01</td><td>0.00</td><td>34:22:56</td><td>-7.84</td></tr><tr><td>P11B05</td><td>0.79</td><td>49.30</td><td>-7.01</td><td>42:23:30</td><td>0.17</td></tr><tr><td>P11C05</td><td>0.79</td><td>55.65</td><td>4.98</td><td>45:12:39</td><td>2.98</td></tr><tr><td>P11D05</td><td>0.79</td><td>53.31</td><td>0.56</td><td>44:30:05</td><td>2.27</td></tr><tr><td>P11E05</td><td>0.79</td><td>56.38</td><td>6.35</td><td>47:01:18</td><td>4.80</td></tr><tr><td>P11F05</td><td>0.79</td><td>45.00</td><td>-15.12</td><td>40:44:54</td><td>-1.48</td></tr><tr><td>P11G05</td><td>0.79</td><td>45.88</td><td>-13.45</td><td>40:58:27</td><td>-1.25</td></tr><tr><td>P11H05</td><td>0.79</td><td>52.21</td><td>-1.51</td><td>41:27:11</td><td>-0.77</td></tr><tr><td>P11A06</td><td>0.79</td><td>59.10</td><td>11.49</td><td>36:16:59</td><td>-5.94</td></tr><tr><td>P11B06</td><td>0.79</td><td>64.86</td><td>22.35</td><td>46:52:59</td><td>4.66</td></tr><tr><td>P11C06</td><td>0.79</td><td>52.58</td><td>-0.83</td><td>46:22:02</td><td>4.14</td></tr><tr><td>P11D06</td><td>0.79</td><td>64.93</td><td>22.48</td><td>45:22:24</td><td>3.15</td></tr><tr><td>P11E06</td><td>0.79</td><td>50.03</td><td>-5.62</td><td>45:22:24</td><td>3.15</td></tr><tr><td>P11F06</td><td>0.79</td><td>63.17</td><td>19.16</td><td>39:32:43</td><td>-2.68</td></tr><tr><td>P11G06</td><td>0.79</td><td>13.48</td><td>-74.57</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P11H06</td><td>0.79</td><td>51.96</td><td>-1.98</td><td>40:16:43</td><td>-1.95</td></tr><tr><td>P11A07</td><td>0.79</td><td>76.29</td><td>43.91</td><td>43:55:19</td><td>1.70</td></tr><tr><td>P11B07</td><td>0.79</td><td>55.92</td><td>5.49</td><td>36:44:32</td><td>-5.48</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P11C07</td><td>0.79</td><td>48.53</td><td>-8.46</td><td>45:19:12</td><td>3.09</td></tr><tr><td>P11D07</td><td>0.79</td><td>52.88</td><td>-0.25</td><td>43:11:29</td><td>0.96</td></tr><tr><td>P11E07</td><td>0.79</td><td>50.48</td><td>-4.77</td><td>43:36:23</td><td>1.38</td></tr><tr><td>P11F07</td><td>0.79</td><td>45.54</td><td>-14.10</td><td>40:03:53</td><td>-2.16</td></tr><tr><td>P11G07</td><td>0.79</td><td>47.54</td><td>-10.32</td><td>42:18:25</td><td>0.08</td></tr><tr><td>P11H07</td><td>0.79</td><td>66.66</td><td>25.75</td><td>46:37:20</td><td>4.40</td></tr><tr><td>P11A08</td><td>0.79</td><td>58.11</td><td>9.61</td><td>37:38:24</td><td>-4.59</td></tr><tr><td>P11B08</td><td>0.79</td><td>52.86</td><td>-0.29</td><td>39:00:32</td><td>-3.22</td></tr><tr><td>P11C08</td><td>0.79</td><td>51.33</td><td>-3.17</td><td>43:06:52</td><td>0.89</td></tr><tr><td>P11D08</td><td>0.79</td><td>54.11</td><td>2.08</td><td>44:39:03</td><td>2.42</td></tr><tr><td>P11E08</td><td>0.79</td><td>55.71</td><td>5.08</td><td>46:45:48</td><td>4.54</td></tr><tr><td>P11F08</td><td>0.79</td><td>53.69</td><td>1.28</td><td>45:47:57</td><td>3.57</td></tr><tr><td>P11G08</td><td>0.79</td><td>46.48</td><td>-12.32</td><td>38:17:23</td><td>-3.94</td></tr><tr><td>P11H08</td><td>0.79</td><td>54.60</td><td>2.99</td><td>40:55:37</td><td>-1.30</td></tr><tr><td>P11A09</td><td>0.79</td><td>78.22</td><td>47.55</td><td>38:03:23</td><td>-4.17</td></tr><tr><td>P11B09</td><td>0.79</td><td>62.26</td><td>17.44</td><td>44:55:09</td><td>2.69</td></tr><tr><td>P11C09</td><td>0.79</td><td>12.19</td><td>-77.00</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P11D09</td><td>0.79</td><td>64.47</td><td>21.62</td><td>48:20:41</td><td>6.12</td></tr><tr><td>P11E09</td><td>0.79</td><td>43.00</td><td>-18.89</td><td>36:19:14</td><td>-5.91</td></tr><tr><td>P11F09</td><td>0.79</td><td>57.07</td><td>7.64</td><td>44:51:47</td><td>2.64</td></tr><tr><td>P11G09</td><td>0.79</td><td>55.02</td><td>3.78</td><td>42:25:29</td><td>0.20</td></tr><tr><td>P11H09</td><td>0.79</td><td>68.66</td><td>29.52</td><td>42:59:40</td><td>0.77</td></tr><tr><td>P11A10</td><td>0.79</td><td>49.58</td><td>-6.47</td><td>46:27:00</td><td>4.22</td></tr><tr><td>P11B10</td><td>0.79</td><td>60.84</td><td>14.76</td><td>50:08:19</td><td>7.91</td></tr><tr><td>P11C10</td><td>0.79</td><td>63.35</td><td>19.50</td><td>49:04:53</td><td>6.85</td></tr><tr><td>P11D10</td><td>0.79</td><td>216.98</td><td>309.29</td><td>136:59:42</td><td>94.77</td></tr><tr><td>P11E10</td><td>0.79</td><td>57.07</td><td>7.66</td><td>43:21:09</td><td>1.13</td></tr><tr><td>P11F10</td><td>0.79</td><td>16.96</td><td>-68.02</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P11G10</td><td>0.79</td><td>52.95</td><td>-0.12</td><td>40:42:28</td><td>-1.52</td></tr><tr><td>P11H10</td><td>0.79</td><td>43.33</td><td>-18.26</td><td>41:38:04</td><td>-0.59</td></tr><tr><td>P11A11</td><td>0.79</td><td>48.93</td><td>-7.71</td><td>42:40:42</td><td>0.45</td></tr><tr><td>P11B11</td><td>0.79</td><td>60.67</td><td>14.45</td><td>44:42:13</td><td>2.48</td></tr><tr><td>P11C11</td><td>0.79</td><td>47.42</td><td>-10.55</td><td>42:36:43</td><td>0.39</td></tr><tr><td>P11D11</td><td>0.79</td><td>51.53</td><td>-2.79</td><td>45:27:19</td><td>3.23</td></tr><tr><td>P11E11</td><td>0.79</td><td>38.44</td><td>-27.49</td><td>42:53:24</td><td>0.66</td></tr><tr><td>P11F11</td><td>0.79</td><td>54.88</td><td>3.53</td><td>41:23:07</td><td>-0.84</td></tr><tr><td>P11G11</td><td>0.79</td><td>44.11</td><td>-16.79</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P11H11</td><td>0.79</td><td>49.89</td><td>-5.89</td><td>38:46:34</td><td>-3.45</td></tr><tr><td>P12 untreated mock-infected cells</td><td>0.85</td><td>262.91 ± 3.58</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P12 untreated infected cells</td><td>0.85</td><td>55.56 ± 6.70</td><td>N.D.</td><td>44:17:43</td><td>N.D.</td></tr><tr><td>P12A02</td><td>0.85</td><td>70.99</td><td>27.77</td><td>45:46:20</td><td>1.48</td></tr><tr><td>P12B02</td><td>0.85</td><td>56.71</td><td>2.06</td><td>45:50:02</td><td>1.54</td></tr><tr><td>P12C02</td><td>0.85</td><td>42.83</td><td>-22.92</td><td>41:21:13</td><td>-2.94</td></tr><tr><td>P12D02</td><td>0.85</td><td>64.70</td><td>16.45</td><td>48:51:55</td><td>4.57</td></tr><tr><td>P12E02</td><td>0.85</td><td>49.62</td><td>-10.70</td><td>42:38:56</td><td>-1.65</td></tr><tr><td>P12F02</td><td>0.85</td><td>48.59</td><td>-12.55</td><td>45:19:50</td><td>1.04</td></tr><tr><td>P12G02</td><td>0.85</td><td>47.93</td><td>-13.74</td><td>42:39:40</td><td>-1.63</td></tr><tr><td>P12H02</td><td>0.85</td><td>50.82</td><td>-8.54</td><td>43:07:25</td><td>-1.17</td></tr><tr><td>P12A03</td><td>0.85</td><td>49.97</td><td>-10.07</td><td>41:57:35</td><td>-2.34</td></tr><tr><td>P12B03</td><td>0.85</td><td>52.71</td><td>-5.14</td><td>44:53:42</td><td>0.60</td></tr><tr><td>P12C03</td><td>0.85</td><td>49.02</td><td>-11.78</td><td>48:49:43</td><td>4.53</td></tr><tr><td>P12D03</td><td>0.85</td><td>32.32</td><td>-41.82</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P12E03</td><td>0.85</td><td>44.00</td><td>-20.81</td><td>39:17:25</td><td>-5.00</td></tr><tr><td>P12F03</td><td>0.85</td><td>57.74</td><td>3.91</td><td>53:53:46</td><td>9.60</td></tr><tr><td>P12G03</td><td>0.85</td><td>53.11</td><td>-4.42</td><td>43:18:22</td><td>-0.99</td></tr><tr><td>P12H03</td><td>0.85</td><td>63.55</td><td>14.38</td><td>49:05:49</td><td>4.80</td></tr><tr><td>P12A04</td><td>0.85</td><td>56.69</td><td>2.03</td><td>39:28:51</td><td>-4.81</td></tr><tr><td>P12B04</td><td>0.85</td><td>62.24</td><td>12.01</td><td>50:06:50</td><td>5.82</td></tr><tr><td>P12C04</td><td>0.85</td><td>46.75</td><td>-15.87</td><td>40:06:40</td><td>-4.18</td></tr><tr><td>P12D04</td><td>0.85</td><td>56.10</td><td>0.97</td><td>45:19:01</td><td>1.02</td></tr><tr><td>P12E04</td><td>0.85</td><td>54.62</td><td>-1.69</td><td>44:32:59</td><td>0.25</td></tr><tr><td>P12F04</td><td>0.85</td><td>52.14</td><td>-6.16</td><td>45:20:49</td><td>1.05</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P12G04</td><td>0.85</td><td>49.54</td><td>-10.85</td><td>45:23:20</td><td>1.09</td></tr><tr><td>P12H04</td><td>0.85</td><td>58.72</td><td>5.67</td><td>43:13:42</td><td>-1.07</td></tr><tr><td>P12A05</td><td>0.85</td><td>66.82</td><td>20.25</td><td>38:53:51</td><td>-5.40</td></tr><tr><td>P12B05</td><td>0.85</td><td>57.63</td><td>3.73</td><td>42:34:05</td><td>-1.73</td></tr><tr><td>P12C05</td><td>0.85</td><td>59.04</td><td>6.25</td><td>42:46:14</td><td>-1.52</td></tr><tr><td>P12D05</td><td>0.85</td><td>46.82</td><td>-15.74</td><td>43:01:53</td><td>-1.26</td></tr><tr><td>P12E05</td><td>0.85</td><td>55.57</td><td>0.01</td><td>42:33:11</td><td>-1.74</td></tr><tr><td>P12F05</td><td>0.85</td><td>56.07</td><td>0.92</td><td>39:15:39</td><td>-5.03</td></tr><tr><td>P12G05</td><td>0.85</td><td>52.93</td><td>-4.73</td><td>43:19:38</td><td>-0.97</td></tr><tr><td>P12H05</td><td>0.85</td><td>71.32</td><td>28.36</td><td>50:02:31</td><td>5.75</td></tr><tr><td>P12A06</td><td>0.85</td><td>1.83</td><td>-96.70</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P12B06</td><td>0.85</td><td>67.06</td><td>20.68</td><td>42:32:11</td><td>-1.76</td></tr><tr><td>P12C06</td><td>0.85</td><td>56.63</td><td>1.93</td><td>44:47:20</td><td>0.49</td></tr><tr><td>P12D06</td><td>0.85</td><td>47.21</td><td>-15.03</td><td>38:37:43</td><td>-5.67</td></tr><tr><td>P12E06</td><td>0.85</td><td>9.01</td><td>-83.78</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P12F06</td><td>0.85</td><td>57.03</td><td>2.64</td><td>36:52:51</td><td>-7.41</td></tr><tr><td>P12G06</td><td>0.85</td><td>50.34</td><td>-9.40</td><td>43:15:35</td><td>-1.04</td></tr><tr><td>P12H06</td><td>0.85</td><td>61.35</td><td>10.42</td><td>46:25:45</td><td>2.13</td></tr><tr><td>P12A07</td><td>0.85</td><td>49.35</td><td>-11.18</td><td>39:15:53</td><td>-5.03</td></tr><tr><td>P12B07</td><td>0.85</td><td>53.83</td><td>-3.12</td><td>42:26:59</td><td>-1.85</td></tr><tr><td>P12C07</td><td>0.85</td><td>63.99</td><td>15.17</td><td>51:39:17</td><td>7.36</td></tr><tr><td>P12D07</td><td>0.85</td><td>43.43</td><td>-21.84</td><td>40:07:58</td><td>-4.16</td></tr><tr><td>P12E07</td><td>0.85</td><td>46.92</td><td>-15.56</td><td>46:12:31</td><td>1.91</td></tr><tr><td>P12F07</td><td>0.85</td><td>51.75</td><td>-6.87</td><td>40:02:34</td><td>-4.25</td></tr><tr><td>P12G07</td><td>0.85</td><td>48.97</td><td>-11.86</td><td>37:39:37</td><td>-6.63</td></tr><tr><td>P12H07</td><td>0.85</td><td>54.10</td><td>-2.64</td><td>38:27:48</td><td>-5.83</td></tr><tr><td>P12A08</td><td>0.85</td><td>63.64</td><td>14.54</td><td>38:24:04</td><td>-5.89</td></tr><tr><td>P12B08</td><td>0.85</td><td>55.25</td><td>-0.56</td><td>43:14:04</td><td>-1.06</td></tr><tr><td>P12C08</td><td>0.85</td><td>49.92</td><td>-10.15</td><td>43:50:19</td><td>-0.46</td></tr><tr><td>P12D08</td><td>0.85</td><td>51.35</td><td>-7.59</td><td>45:58:24</td><td>1.68</td></tr><tr><td>P12E08</td><td>0.85</td><td>61.94</td><td>11.47</td><td>47:19:20</td><td>3.03</td></tr><tr><td>P12F08</td><td>0.85</td><td>51.05</td><td>-8.13</td><td>43:37:05</td><td>-0.68</td></tr><tr><td>P12G08</td><td>0.85</td><td>14.89</td><td>-73.20</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P12H08</td><td>0.85</td><td>68.92</td><td>24.03</td><td>46:24:20</td><td>2.11</td></tr><tr><td>P12A09</td><td>0.85</td><td>56.31</td><td>1.34</td><td>48:51:32</td><td>4.56</td></tr><tr><td>P12B09</td><td>0.85</td><td>40.10</td><td>-27.83</td><td>43:48:03</td><td>-0.49</td></tr><tr><td>P12C09</td><td>0.85</td><td>48.29</td><td>-13.09</td><td>49:38:19</td><td>5.34</td></tr><tr><td>P12D09</td><td>0.85</td><td>47.96</td><td>-13.69</td><td>44:27:18</td><td>0.16</td></tr><tr><td>P12E09</td><td>0.85</td><td>42.27</td><td>-23.92</td><td>43:39:16</td><td>-0.64</td></tr><tr><td>P12F09</td><td>0.85</td><td>58.67</td><td>5.60</td><td>48:00:58</td><td>3.72</td></tr><tr><td>P12G09</td><td>0.85</td><td>52.90</td><td>-4.79</td><td>43:20:29</td><td>-0.95</td></tr><tr><td>P12H09</td><td>0.85</td><td>61.42</td><td>10.54</td><td>43:34:59</td><td>-0.71</td></tr><tr><td>P12A10</td><td>0.85</td><td>59.30</td><td>6.73</td><td>58:19:14</td><td>14.03</td></tr><tr><td>P12B10</td><td>0.85</td><td>49.55</td><td>-10.82</td><td>44:08:50</td><td>-0.15</td></tr><tr><td>P12C10</td><td>0.85</td><td>48.10</td><td>-13.43</td><td>46:13:14</td><td>1.93</td></tr><tr><td>P12D10</td><td>0.85</td><td>46.37</td><td>-16.54</td><td>43:58:59</td><td>-0.31</td></tr><tr><td>P12E10</td><td>0.85</td><td>45.00</td><td>-19.02</td><td>37:36:37</td><td>-6.68</td></tr><tr><td>P12F10</td><td>0.85</td><td>50.76</td><td>-8.65</td><td>43:04:31</td><td>-1.22</td></tr><tr><td>P12G10</td><td>0.85</td><td>67.36</td><td>21.23</td><td>44:26:02</td><td>0.14</td></tr><tr><td>P12H10</td><td>0.85</td><td>56.52</td><td>1.72</td><td>44:07:37</td><td>-0.17</td></tr><tr><td>P12A11</td><td>0.85</td><td>54.97</td><td>-1.08</td><td>44:05:41</td><td>-0.20</td></tr><tr><td>P12B11</td><td>0.85</td><td>51.79</td><td>-6.79</td><td>42:18:16</td><td>-1.99</td></tr><tr><td>P12C11</td><td>0.85</td><td>56.03</td><td>0.85</td><td>48:07:59</td><td>3.84</td></tr><tr><td>P12D11</td><td>0.85</td><td>55.04</td><td>-0.94</td><td>47:23:54</td><td>3.10</td></tr><tr><td>P12E11</td><td>0.85</td><td>42.29</td><td>-23.89</td><td>43:13:57</td><td>-1.06</td></tr><tr><td>P12F11</td><td>0.85</td><td>46.95</td><td>-15.50</td><td>43:24:39</td><td>-0.88</td></tr><tr><td>P12G11</td><td>0.85</td><td>57.69</td><td>3.83</td><td>44:25:06</td><td>0.12</td></tr><tr><td>P12H11</td><td>0.85</td><td>59.40</td><td>6.90</td><td>43:55:32</td><td>-0.37</td></tr><tr><td>P13 untreated mock-infected cells</td><td>0.87</td><td>240.87 ± 6.33</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P13 untreated infected cells</td><td>0.87</td><td>45.97 ± 2.20</td><td>N.D.</td><td>40:36:49</td><td>N.D.</td></tr><tr><td>P13A02</td><td>0.87</td><td>49.26</td><td>7.15</td><td>43:58:51</td><td>3.37</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P13B02</td><td>0.87</td><td>57.56</td><td>25.21</td><td>43:38:14</td><td>3.02</td></tr><tr><td>P13C02</td><td>0.87</td><td>41.33</td><td>-10.08</td><td>42:14:35</td><td>1.63</td></tr><tr><td>P13D02</td><td>0.87</td><td>39.97</td><td>-13.05</td><td>41:43:23</td><td>1.11</td></tr><tr><td>P13E02</td><td>0.87</td><td>41.15</td><td>-10.49</td><td>41:24:39</td><td>0.80</td></tr><tr><td>P13F02</td><td>0.87</td><td>42.64</td><td>-7.24</td><td>38:55:58</td><td>-1.68</td></tr><tr><td>P13G02</td><td>0.87</td><td>48.18</td><td>4.81</td><td>41:21:52</td><td>0.75</td></tr><tr><td>P13H02</td><td>0.87</td><td>61.46</td><td>33.71</td><td>53:29:12</td><td>12.87</td></tr><tr><td>P13A03</td><td>0.87</td><td>44.69</td><td>-2.79</td><td>43:07:36</td><td>2.51</td></tr><tr><td>P13B03</td><td>0.87</td><td>60.56</td><td>31.74</td><td>47:20:41</td><td>6.73</td></tr><tr><td>P13C03</td><td>0.87</td><td>48.01</td><td>4.44</td><td>44:08:28</td><td>3.53</td></tr><tr><td>P13D03</td><td>0.87</td><td>45.84</td><td>-0.28</td><td>43:05:53</td><td>2.48</td></tr><tr><td>P13E03</td><td>0.87</td><td>48.40</td><td>5.28</td><td>48:13:03</td><td>7.60</td></tr><tr><td>P13F03</td><td>0.87</td><td>43.22</td><td>-5.97</td><td>41:26:46</td><td>0.83</td></tr><tr><td>P13G03</td><td>0.87</td><td>48.61</td><td>5.76</td><td>42:04:35</td><td>1.46</td></tr><tr><td>P13H03</td><td>0.87</td><td>54.65</td><td>18.88</td><td>45:49:47</td><td>5.22</td></tr><tr><td>P13A04</td><td>0.87</td><td>31.31</td><td>-31.90</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P13B04</td><td>0.87</td><td>58.30</td><td>26.84</td><td>48:56:41</td><td>8.33</td></tr><tr><td>P13C04</td><td>0.87</td><td>73.03</td><td>58.88</td><td>48:53:04</td><td>8.27</td></tr><tr><td>P13D04</td><td>0.87</td><td>34.13</td><td>-25.75</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P13E04</td><td>0.87</td><td>51.41</td><td>11.85</td><td>45:25:13</td><td>4.81</td></tr><tr><td>P13F04</td><td>0.87</td><td>49.67</td><td>8.05</td><td>46:32:05</td><td>5.92</td></tr><tr><td>P13G04</td><td>0.87</td><td>59.37</td><td>29.15</td><td>45:47:38</td><td>5.18</td></tr><tr><td>P13H04</td><td>0.87</td><td>52.62</td><td>14.48</td><td>43:34:03</td><td>2.95</td></tr><tr><td>P13A05</td><td>0.87</td><td>48.10</td><td>4.65</td><td>43:23:47</td><td>2.78</td></tr><tr><td>P13B05</td><td>0.87</td><td>46.32</td><td>0.76</td><td>42:59:25</td><td>2.38</td></tr><tr><td>P13C05</td><td>0.87</td><td>47.50</td><td>3.34</td><td>42:02:43</td><td>1.43</td></tr><tr><td>P13D05</td><td>0.87</td><td>46.84</td><td>1.90</td><td>45:03:12</td><td>4.44</td></tr><tr><td>P13E05</td><td>0.87</td><td>37.83</td><td>-17.71</td><td>39:23:49</td><td>-1.22</td></tr><tr><td>P13F05</td><td>0.87</td><td>35.96</td><td>-21.77</td><td>41:14:45</td><td>0.63</td></tr><tr><td>P13G05</td><td>0.87</td><td>53.06</td><td>15.42</td><td>42:24:53</td><td>1.80</td></tr><tr><td>P13H05</td><td>0.87</td><td>51.37</td><td>11.75</td><td>42:11:05</td><td>1.57</td></tr><tr><td>P13A06</td><td>0.87</td><td>53.69</td><td>16.80</td><td>46:48:29</td><td>6.19</td></tr><tr><td>P13B06</td><td>0.87</td><td>48.28</td><td>5.03</td><td>44:36:33</td><td>4.00</td></tr><tr><td>P13C06</td><td>0.87</td><td>45.27</td><td>-1.52</td><td>42:51:25</td><td>2.24</td></tr><tr><td>P13D06</td><td>0.87</td><td>50.07</td><td>8.93</td><td>45:23:56</td><td>4.79</td></tr><tr><td>P13E06</td><td>0.87</td><td>49.83</td><td>8.40</td><td>45:23:56</td><td>4.79</td></tr><tr><td>P13F06</td><td>0.87</td><td>43.34</td><td>-5.72</td><td>41:55:23</td><td>1.31</td></tr><tr><td>P13G06</td><td>0.87</td><td>50.14</td><td>9.07</td><td>45:09:23</td><td>4.54</td></tr><tr><td>P13H06</td><td>0.87</td><td>49.32</td><td>7.30</td><td>43:57:53</td><td>3.35</td></tr><tr><td>P13A07</td><td>0.87</td><td>50.22</td><td>9.24</td><td>42:34:14</td><td>1.96</td></tr><tr><td>P13B07</td><td>0.87</td><td>43.19</td><td>-6.05</td><td>38:27:50</td><td>-2.15</td></tr><tr><td>P13C07</td><td>0.87</td><td>28.92</td><td>-37.09</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P13D07</td><td>0.87</td><td>46.03</td><td>0.13</td><td>42:59:45</td><td>2.38</td></tr><tr><td>P13E07</td><td>0.87</td><td>43.07</td><td>-6.29</td><td>38:38:37</td><td>-1.97</td></tr><tr><td>P13F07</td><td>0.87</td><td>50.01</td><td>8.79</td><td>40:20:53</td><td>-0.27</td></tr><tr><td>P13G07</td><td>0.87</td><td>45.84</td><td>-0.28</td><td>41:43:31</td><td>1.11</td></tr><tr><td>P13H07</td><td>0.87</td><td>48.25</td><td>4.97</td><td>40:49:27</td><td>0.21</td></tr><tr><td>P13A08</td><td>0.87</td><td>45.47</td><td>-1.08</td><td>41:13:32</td><td>0.61</td></tr><tr><td>P13B08</td><td>0.87</td><td>53.40</td><td>16.16</td><td>44:55:54</td><td>4.32</td></tr><tr><td>P13C08</td><td>0.87</td><td>0.35</td><td>-99.24</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P13D08</td><td>0.87</td><td>49.11</td><td>6.84</td><td>38:49:42</td><td>-1.79</td></tr><tr><td>P13E08</td><td>0.87</td><td>46.15</td><td>0.40</td><td>40:32:28</td><td>-0.07</td></tr><tr><td>P13F08</td><td>0.87</td><td>66.58</td><td>44.85</td><td>44:56:23</td><td>4.33</td></tr><tr><td>P13G08</td><td>0.87</td><td>56.56</td><td>23.04</td><td>43:24:52</td><td>2.80</td></tr><tr><td>P13H08</td><td>0.87</td><td>49.77</td><td>8.27</td><td>43:31:39</td><td>2.91</td></tr><tr><td>P13A09</td><td>0.87</td><td>43.73</td><td>-4.87</td><td>44:28:42</td><td>3.86</td></tr><tr><td>P13B09</td><td>0.87</td><td>50.38</td><td>9.60</td><td>41:18:47</td><td>0.70</td></tr><tr><td>P13C09</td><td>0.87</td><td>47.11</td><td>2.48</td><td>41:58:24</td><td>1.36</td></tr><tr><td>P13D09</td><td>0.87</td><td>47.53</td><td>3.39</td><td>44:13:15</td><td>3.61</td></tr><tr><td>P13E09</td><td>0.87</td><td>46.41</td><td>0.95</td><td>39:25:20</td><td>-1.19</td></tr><tr><td>P13F09</td><td>0.87</td><td>57.49</td><td>25.07</td><td>44:13:45</td><td>3.62</td></tr><tr><td>P13G09</td><td>0.87</td><td>55.82</td><td>21.44</td><td>43:13:33</td><td>2.61</td></tr><tr><td>P13H09</td><td>0.87</td><td>40.07</td><td>-12.84</td><td>43:04:27</td><td>2.46</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P13A10</td><td>0.87</td><td>48.58</td><td>5.69</td><td>44:47:35</td><td>4.18</td></tr><tr><td>P13B10</td><td>0.87</td><td>48.50</td><td>5.51</td><td>42:51:05</td><td>2.24</td></tr><tr><td>P13C10</td><td>0.87</td><td>49.52</td><td>7.73</td><td>41:25:20</td><td>0.81</td></tr><tr><td>P13D10</td><td>0.87</td><td>54.81</td><td>19.24</td><td>47:07:39</td><td>6.51</td></tr><tr><td>P13E10</td><td>0.87</td><td>50.82</td><td>10.56</td><td>43:52:42</td><td>3.26</td></tr><tr><td>P13F10</td><td>0.87</td><td>47.57</td><td>3.48</td><td>39:34:29</td><td>-1.04</td></tr><tr><td>P13G10</td><td>0.87</td><td>51.66</td><td>12.38</td><td>41:01:39</td><td>0.41</td></tr><tr><td>P13H10</td><td>0.87</td><td>51.40</td><td>11.81</td><td>43:44:03</td><td>3.12</td></tr><tr><td>P13A11</td><td>0.87</td><td>58.29</td><td>26.80</td><td>49:09:11</td><td>8.54</td></tr><tr><td>P13B11</td><td>0.87</td><td>45.30</td><td>-1.44</td><td>40:28:18</td><td>-0.14</td></tr><tr><td>P13C11</td><td>0.87</td><td>45.83</td><td>-0.30</td><td>41:23:07</td><td>0.77</td></tr><tr><td>P13D11</td><td>0.87</td><td>49.10</td><td>6.81</td><td>42:25:21</td><td>1.81</td></tr><tr><td>P13E11</td><td>0.87</td><td>45.22</td><td>-1.63</td><td>39:48:05</td><td>-0.81</td></tr><tr><td>P13F11</td><td>0.87</td><td>51.83</td><td>12.76</td><td>38:05:42</td><td>-2.52</td></tr><tr><td>P13G11</td><td>0.87</td><td>49.62</td><td>7.94</td><td>42:21:46</td><td>1.75</td></tr><tr><td>P13H11</td><td>0.87</td><td>45.54</td><td>-0.92</td><td>22:16:26</td><td>-18.34</td></tr><tr><td>P14 untreated</td><td>0.52</td><td>309.86 ± 39.49</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>mock-infected cells</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>P14 untreated infected cells</td><td>0.52</td><td>48.43 ± 2.22</td><td>N.D.</td><td>43:27:35</td><td>N.D.</td></tr><tr><td>P14A02</td><td>0.52</td><td>52.72</td><td>8.85</td><td>44:38:04</td><td>1.17</td></tr><tr><td>P14B02</td><td>0.52</td><td>73.67</td><td>52.12</td><td>43:51:33</td><td>0.40</td></tr><tr><td>P14C02</td><td>0.52</td><td>40.91</td><td>-15.52</td><td>40:24:35</td><td>-3.05</td></tr><tr><td>P14D02</td><td>0.52</td><td>48.61</td><td>0.38</td><td>46:32:27</td><td>3.08</td></tr><tr><td>P14E02</td><td>0.52</td><td>51.23</td><td>5.78</td><td>46:26:48</td><td>2.99</td></tr><tr><td>P14F02</td><td>0.52</td><td>52.43</td><td>8.25</td><td>43:12:44</td><td>-0.25</td></tr><tr><td>P14G02</td><td>0.52</td><td>43.29</td><td>-10.62</td><td>41:07:01</td><td>-2.34</td></tr><tr><td>P14H02</td><td>0.52</td><td>62.55</td><td>29.16</td><td>48:53:27</td><td>5.43</td></tr><tr><td>P14A03</td><td>0.52</td><td>54.97</td><td>13.49</td><td>44:45:45</td><td>1.30</td></tr><tr><td>P14B03</td><td>0.52</td><td>50.22</td><td>3.70</td><td>44:30:09</td><td>1.04</td></tr><tr><td>P14C03</td><td>0.52</td><td>62.72</td><td>29.50</td><td>47:45:24</td><td>4.30</td></tr><tr><td>P14D03</td><td>0.52</td><td>40.77</td><td>-15.83</td><td>40:31:55</td><td>-2.93</td></tr><tr><td>P14E03</td><td>0.52</td><td>89.42</td><td>84.64</td><td>51:59:07</td><td>8.53</td></tr><tr><td>P14F03</td><td>0.52</td><td>59.10</td><td>22.03</td><td>39:12:13</td><td>-4.26</td></tr><tr><td>P14G03</td><td>0.52</td><td>54.66</td><td>12.87</td><td>43:31:04</td><td>0.06</td></tr><tr><td>P14H03</td><td>0.52</td><td>53.67</td><td>10.83</td><td>44:57:40</td><td>1.50</td></tr><tr><td>P14A04</td><td>0.52</td><td>82.86</td><td>71.08</td><td>49:20:13</td><td>5.88</td></tr><tr><td>P14B04</td><td>0.52</td><td>46.67</td><td>-3.63</td><td>44:15:49</td><td>0.80</td></tr><tr><td>P14C04</td><td>0.52</td><td>54.84</td><td>13.24</td><td>45:15:37</td><td>1.80</td></tr><tr><td>P14D04</td><td>0.52</td><td>50.00</td><td>3.24</td><td>43:36:22</td><td>0.15</td></tr><tr><td>P14E04</td><td>0.52</td><td>48.35</td><td>-0.17</td><td>41:31:01</td><td>-1.94</td></tr><tr><td>P14F04</td><td>0.52</td><td>29.50</td><td>-39.09</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P14G04</td><td>0.52</td><td>48.95</td><td>1.08</td><td>43:48:02</td><td>0.34</td></tr><tr><td>P14H04</td><td>0.52</td><td>54.11</td><td>11.72</td><td>43:09:01</td><td>-0.31</td></tr><tr><td>P14A05</td><td>0.52</td><td>69.33</td><td>43.15</td><td>40:30:05</td><td>-2.96</td></tr><tr><td>P14B05</td><td>0.52</td><td>48.62</td><td>0.38</td><td>43:37:58</td><td>0.17</td></tr><tr><td>P14C05</td><td>0.52</td><td>52.92</td><td>9.28</td><td>42:07:36</td><td>-1.33</td></tr><tr><td>P14D05</td><td>0.52</td><td>45.45</td><td>-6.16</td><td>41:29:52</td><td>-1.96</td></tr><tr><td>P14E05</td><td>0.52</td><td>48.36</td><td>-0.15</td><td>43:47:32</td><td>0.33</td></tr><tr><td>P14F05</td><td>0.52</td><td>46.99</td><td>-2.97</td><td>44:41:58</td><td>1.24</td></tr><tr><td>P14G05</td><td>0.52</td><td>47.47</td><td>-1.99</td><td>43:44:17</td><td>0.28</td></tr><tr><td>P14H05</td><td>0.52</td><td>46.29</td><td>-4.42</td><td>42:22:02</td><td>-1.09</td></tr><tr><td>P14A06</td><td>0.52</td><td>31.97</td><td>-34.00</td><td>40:42:24</td><td>-2.75</td></tr><tr><td>P14B06</td><td>0.52</td><td>51.69</td><td>6.73</td><td>45:17:03</td><td>1.82</td></tr><tr><td>P14C06</td><td>0.52</td><td>45.87</td><td>-5.29</td><td>42:25:44</td><td>-1.03</td></tr><tr><td>P14D06</td><td>0.52</td><td>54.73</td><td>13.02</td><td>46:36:33</td><td>3.15</td></tr><tr><td>P14E06</td><td>0.52</td><td>44.23</td><td>-8.68</td><td>46:36:33</td><td>3.15</td></tr><tr><td>P14F06</td><td>0.52</td><td>47.36</td><td>-2.21</td><td>42:08:41</td><td>-1.32</td></tr><tr><td>P14G06</td><td>0.52</td><td>50.51</td><td>4.29</td><td>46:29:03</td><td>3.02</td></tr><tr><td>P14H06</td><td>0.52</td><td>44.83</td><td>-7.44</td><td>41:43:30</td><td>-1.73</td></tr><tr><td>P14A07</td><td>0.52</td><td>68.89</td><td>42.25</td><td>43:05:12</td><td>-0.37</td></tr><tr><td>P14B07</td><td>0.52</td><td>115.04</td><td>137.53</td><td>108:06:35</td><td>64.65</td></tr><tr><td>P14C07</td><td>0.52</td><td>37.93</td><td>-21.68</td><td>39:17:19</td><td>-4.17</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P14D07</td><td>0.52</td><td>52.56</td><td>8.53</td><td>42:09:59</td><td>-1.29</td></tr><tr><td>P14E07</td><td>0.52</td><td>52.50</td><td>8.41</td><td>43:55:34</td><td>0.47</td></tr><tr><td>P14F07</td><td>0.52</td><td>32.41</td><td>-33.08</td><td>40:44:29</td><td>-2.72</td></tr><tr><td>P14G07</td><td>0.52</td><td>55.27</td><td>14.12</td><td>45:05:19</td><td>1.63</td></tr><tr><td>P14H07</td><td>0.52</td><td>45.13</td><td>-6.81</td><td>43:26:11</td><td>-0.02</td></tr><tr><td>P14B08</td><td>0.52</td><td>59.00</td><td>21.82</td><td>44:15:55</td><td>0.81</td></tr><tr><td>P14C08</td><td>0.52</td><td>43.28</td><td>-10.64</td><td>38:44:35</td><td>-4.72</td></tr><tr><td>P14D08</td><td>0.52</td><td>51.86</td><td>7.07</td><td>45:10:32</td><td>1.72</td></tr><tr><td>P14E08</td><td>0.52</td><td>50.46</td><td>4.19</td><td>39:34:00</td><td>-3.89</td></tr><tr><td>P14F08</td><td>0.52</td><td>65.84</td><td>35.95</td><td>48:40:19</td><td>5.21</td></tr><tr><td>P14G08</td><td>0.52</td><td>52.21</td><td>7.81</td><td>44:29:41</td><td>1.03</td></tr><tr><td>P14H08</td><td>0.52</td><td>50.50</td><td>4.28</td><td>42:59:07</td><td>-0.47</td></tr><tr><td>P14A09</td><td>0.52</td><td>42.45</td><td>-12.35</td><td>40:19:31</td><td>-3.13</td></tr><tr><td>P14B09</td><td>0.52</td><td>53.00</td><td>9.43</td><td>46:02:10</td><td>2.58</td></tr><tr><td>P14C09</td><td>0.52</td><td>57.31</td><td>18.34</td><td>58:42:38</td><td>15.25</td></tr><tr><td>P14D09</td><td>0.52</td><td>44.64</td><td>-7.82</td><td>42:06:58</td><td>-1.34</td></tr><tr><td>P14E09</td><td>0.52</td><td>53.45</td><td>10.36</td><td>41:53:46</td><td>-1.56</td></tr><tr><td>P14F09</td><td>0.52</td><td>36.48</td><td>-24.68</td><td>43:05:16</td><td>-0.37</td></tr><tr><td>P14G09</td><td>0.52</td><td>49.07</td><td>1.32</td><td>42:42:19</td><td>-0.75</td></tr><tr><td>P14H09</td><td>0.52</td><td>48.89</td><td>0.95</td><td>43:12:15</td><td>-0.26</td></tr><tr><td>P14A10</td><td>0.52</td><td>0.79</td><td>-98.37</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P14B10</td><td>0.52</td><td>53.55</td><td>10.57</td><td>45:02:09</td><td>1.58</td></tr><tr><td>P14C10</td><td>0.52</td><td>50.86</td><td>5.02</td><td>46:12:45</td><td>2.75</td></tr><tr><td>P14D10</td><td>0.52</td><td>44.39</td><td>-8.35</td><td>43:40:06</td><td>0.21</td></tr><tr><td>P14E10</td><td>0.52</td><td>38.76</td><td>-19.96</td><td>36:47:35</td><td>-6.67</td></tr><tr><td>P14F10</td><td>0.52</td><td>42.43</td><td>-12.39</td><td>39:24:03</td><td>-4.06</td></tr><tr><td>P14G10</td><td>0.52</td><td>37.65</td><td>-22.25</td><td>35:18:15</td><td>-8.16</td></tr><tr><td>P14H10</td><td>0.52</td><td>49.55</td><td>2.31</td><td>35:39:56</td><td>-7.79</td></tr><tr><td>P14A11</td><td>0.52</td><td>50.23</td><td>3.71</td><td>40:51:12</td><td>-2.61</td></tr><tr><td>P14B11</td><td>0.52</td><td>50.38</td><td>4.02</td><td>44:12:07</td><td>0.74</td></tr><tr><td>P14C11</td><td>0.52</td><td>38.68</td><td>-20.14</td><td>39:52:39</td><td>-3.58</td></tr><tr><td>P14D11</td><td>0.52</td><td>36.22</td><td>-25.21</td><td>14:50:19</td><td>-28.62</td></tr><tr><td>P14E11</td><td>0.52</td><td>45.31</td><td>-6.44</td><td>40:56:35</td><td>-2.52</td></tr><tr><td>P14F11</td><td>0.52</td><td>44.12</td><td>-8.90</td><td>41:37:27</td><td>-1.84</td></tr><tr><td>P14G11</td><td>0.52</td><td>37.02</td><td>-23.57</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P14H11</td><td>0.52</td><td>49.96</td><td>3.17</td><td>42:34:10</td><td>-0.89</td></tr><tr><td>P16 untreated mock-infected cells</td><td>0.65</td><td>325.19 ± 19.16</td><td>N.D.</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P16 untreated infected cells</td><td>0.65</td><td>72.55 ± 10.12</td><td>N.D.</td><td>48:07:24</td><td>N.D.</td></tr><tr><td>P16A02</td><td>0.65</td><td>22.74</td><td>-68.66</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P16B02</td><td>0.65</td><td>65.78</td><td>-9.34</td><td>47:20:12</td><td>-0.79</td></tr><tr><td>P16C02</td><td>0.65</td><td>46.70</td><td>-35.63</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P16D02</td><td>0.65</td><td>15.71</td><td>-78.34</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P16E02</td><td>0.65</td><td>80.53</td><td>10.99</td><td>51:17:28</td><td>3.17</td></tr><tr><td>P16F02</td><td>0.65</td><td>82.54</td><td>13.76</td><td>48:15:35</td><td>0.14</td></tr><tr><td>P16G02</td><td>0.65</td><td>78.92</td><td>8.78</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P16H02</td><td>0.65</td><td>92.61</td><td>27.64</td><td>59:06:09</td><td>10.98</td></tr><tr><td>P16A03</td><td>0.65</td><td>100.87</td><td>39.04</td><td>52:19:16</td><td>4.20</td></tr><tr><td>P16B03</td><td>0.65</td><td>87.64</td><td>20.80</td><td>52:07:04</td><td>3.99</td></tr><tr><td>P16C03</td><td>0.65</td><td>88.51</td><td>21.99</td><td>49:08:25</td><td>1.02</td></tr><tr><td>P16D03</td><td>0.65</td><td>101.15</td><td>39.42</td><td>52:43:34</td><td>4.60</td></tr><tr><td>P16E03</td><td>0.65</td><td>65.01</td><td>-10.39</td><td>42:41:04</td><td>-5.44</td></tr><tr><td>P16F03</td><td>0.65</td><td>74.18</td><td>2.24</td><td>48:10:46</td><td>0.06</td></tr><tr><td>P16G03</td><td>0.65</td><td>72.93</td><td>0.52</td><td>41:15:17</td><td>-6.87</td></tr><tr><td>P16H03</td><td>0.65</td><td>81.03</td><td>11.69</td><td>47:16:49</td><td>-0.84</td></tr><tr><td>P16A04</td><td>0.65</td><td>100.19</td><td>38.09</td><td>48:06:50</td><td>-0.01</td></tr><tr><td>P16B04</td><td>0.65</td><td>117.36</td><td>61.76</td><td>49:18:48</td><td>1.19</td></tr><tr><td>P16C04</td><td>0.65</td><td>139.51</td><td>92.29</td><td>51:35:19</td><td>3.47</td></tr><tr><td>P16D04</td><td>0.65</td><td>51.78</td><td>-28.63</td><td>54:09:56</td><td>6.04</td></tr><tr><td>P16E04</td><td>0.65</td><td>80.54</td><td>11.01</td><td>46:28:05</td><td>-1.66</td></tr><tr><td>P16F04</td><td>0.65</td><td>64.21</td><td>-11.51</td><td>47:25:47</td><td>-0.69</td></tr><tr><td>P16G04</td><td>0.65</td><td>136.34</td><td>87.91</td><td>58:52:37</td><td>10.75</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 1 (continued)**</caption><thead><tr><th>Compound code</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>P16H04</td><td>0.65</td><td>94.13</td><td>29.75</td><td>43:43:36</td><td>-4.40</td></tr><tr><td>P16A05</td><td>0.65</td><td>123.50</td><td>70.23</td><td>57:08:50</td><td>9.02</td></tr><tr><td>P16B05</td><td>0.65</td><td>47.28</td><td>-34.83</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P16C05</td><td>0.65</td><td>106.68</td><td>47.04</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P16D05</td><td>0.65</td><td>82.80</td><td>14.13</td><td>53:18:05</td><td>5.18</td></tr><tr><td>P16E05</td><td>0.65</td><td>36.21</td><td>-50.09</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P16F05</td><td>0.65</td><td>112.15</td><td>54.58</td><td>49:08:38</td><td>1.02</td></tr><tr><td>P16G05</td><td>0.65</td><td>33.24</td><td>-54.19</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P16H05</td><td>0.65</td><td>85.15</td><td>17.36</td><td>50:27:34</td><td>2.34</td></tr><tr><td>P16A06</td><td>0.65</td><td>84.58</td><td>16.58</td><td>44:36:58</td><td>-3.51</td></tr><tr><td>P16B06</td><td>0.65</td><td>62.51</td><td>-13.84</td><td>45:38:16</td><td>-2.49</td></tr><tr><td>P16C06</td><td>0.65</td><td>80.23</td><td>10.58</td><td>47:10:24</td><td>-0.95</td></tr><tr><td>P16D06</td><td>0.65</td><td>118.79</td><td>63.73</td><td>60:30:56</td><td>12.39</td></tr><tr><td>P16E06</td><td>0.65</td><td>58.75</td><td>-19.03</td><td>60:30:56</td><td>12.39</td></tr><tr><td>P16F06</td><td>0.65</td><td>90.81</td><td>25.16</td><td>48:30:57</td><td>0.39</td></tr><tr><td>P16G06</td><td>0.65</td><td>104.23</td><td>43.66</td><td>47:23:24</td><td>-0.73</td></tr><tr><td>P16H06</td><td>0.65</td><td>99.63</td><td>37.33</td><td>51:55:42</td><td>3.80</td></tr><tr><td>P16A07</td><td>0.65</td><td>94.94</td><td>30.85</td><td>49:17:53</td><td>1.17</td></tr><tr><td>P16B07</td><td>0.65</td><td>91.68</td><td>26.36</td><td>45:17:25</td><td>-2.83</td></tr><tr><td>P16C07</td><td>0.65</td><td>99.82</td><td>37.58</td><td>50:13:50</td><td>2.11</td></tr><tr><td>P16D07</td><td>0.65</td><td>85.81</td><td>18.27</td><td>47:22:31</td><td>-0.75</td></tr><tr><td>P16E07</td><td>0.65</td><td>94.82</td><td>30.70</td><td>47:22:13</td><td>-0.75</td></tr><tr><td>P16F07</td><td>0.65</td><td>72.78</td><td>0.32</td><td>40:58:06</td><td>-7.16</td></tr><tr><td>P16G07</td><td>0.65</td><td>77.03</td><td>6.17</td><td>51:15:17</td><td>3.13</td></tr><tr><td>P16H07</td><td>0.65</td><td>88.31</td><td>21.72</td><td>42:39:59</td><td>-5.46</td></tr><tr><td>P16A08</td><td>0.65</td><td>92.80</td><td>27.91</td><td>57:39:01</td><td>9.53</td></tr><tr><td>P16B08</td><td>0.65</td><td>39.48</td><td>-45.59</td><td>42:29:12</td><td>-5.64</td></tr><tr><td>P16C08</td><td>0.65</td><td>66.18</td><td>-8.78</td><td>42:40:52</td><td>-5.44</td></tr><tr><td>P16D08</td><td>0.65</td><td>77.07</td><td>6.23</td><td>48:35:04</td><td>0.46</td></tr><tr><td>P16E08</td><td>0.65</td><td>104.06</td><td>43.43</td><td>52:53:57</td><td>4.78</td></tr><tr><td>P16F08</td><td>0.65</td><td>115.42</td><td>59.09</td><td>51:57:14</td><td>3.83</td></tr><tr><td>P16G08</td><td>0.65</td><td>58.49</td><td>-19.39</td><td>39:31:57</td><td>-8.59</td></tr><tr><td>P16H08</td><td>0.65</td><td>47.76</td><td>-34.18</td><td>44:14:45</td><td>-3.88</td></tr><tr><td>P16A09</td><td>0.65</td><td>97.25</td><td>34.05</td><td>46:32:16</td><td>-1.59</td></tr><tr><td>P16B09</td><td>0.65</td><td>60.32</td><td>-16.86</td><td>47:33:56</td><td>-0.56</td></tr><tr><td>P16C09</td><td>0.65</td><td>65.14</td><td>-10.22</td><td>48:21:49</td><td>0.24</td></tr><tr><td>P16D09</td><td>0.65</td><td>84.42</td><td>16.36</td><td>44:58:28</td><td>-3.15</td></tr><tr><td>P16E09</td><td>0.65</td><td>90.70</td><td>25.01</td><td>52:29:13</td><td>4.36</td></tr><tr><td>P16F09</td><td>0.65</td><td>69.02</td><td>-4.87</td><td>39:40:11</td><td>-8.45</td></tr><tr><td>P16G09</td><td>0.65</td><td>156.75</td><td>116.05</td><td>60:23:56</td><td>12.28</td></tr><tr><td>P16H09</td><td>0.65</td><td>110.18</td><td>51.86</td><td>52:06:08</td><td>3.98</td></tr><tr><td>P16A10</td><td>0.65</td><td>123.72</td><td>70.53</td><td>62:49:52</td><td>14.71</td></tr><tr><td>P16B10</td><td>0.65</td><td>83.79</td><td>15.49</td><td>51:37:10</td><td>3.50</td></tr><tr><td>P16C10</td><td>0.65</td><td>54.08</td><td>-25.46</td><td>49:52:16</td><td>1.75</td></tr><tr><td>P16D10</td><td>0.65</td><td>87.47</td><td>20.56</td><td>45:57:42</td><td>-2.16</td></tr><tr><td>P16E10</td><td>0.65</td><td>15.30</td><td>-78.91</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P16F10</td><td>0.65</td><td>119.75</td><td>65.06</td><td>51:05:19</td><td>2.97</td></tr><tr><td>P16G10</td><td>0.65</td><td>75.11</td><td>3.53</td><td>46:02:46</td><td>-2.08</td></tr><tr><td>P16H10</td><td>0.65</td><td>129.15</td><td>78.01</td><td>48:27:01</td><td>0.33</td></tr><tr><td>P16A11</td><td>0.65</td><td>104.71</td><td>44.32</td><td>51:04:28</td><td>2.95</td></tr><tr><td>P16B11</td><td>0.65</td><td>37.29</td><td>-48.61</td><td>N.D.</td><td>N.D.</td></tr><tr><td>P16C11</td><td>0.65</td><td>86.83</td><td>19.68</td><td>50:46:23</td><td>2.65</td></tr><tr><td>P16D11</td><td>0.65</td><td>90.03</td><td>24.09</td><td>47:51:31</td><td>-0.26</td></tr><tr><td>P16E11</td><td>0.65</td><td>82.22</td><td>13.32</td><td>47:23:57</td><td>-0.72</td></tr><tr><td>P16F11</td><td>0.65</td><td>68.28</td><td>-5.88</td><td>42:23:46</td><td>-5.73</td></tr><tr><td>P16G11</td><td>0.65</td><td>50.99</td><td>-29.73</td><td>39:41:53</td><td>-8.43</td></tr><tr><td>P16H11</td><td>0.65</td><td>97.78</td><td>34.77</td><td>44:40:25</td><td>-3.45</td></tr></tbody></table>
<caption>**Table 2**</caption>

Screening of 1,651 compounds from the Centre d'Etudes et de Recherche sur le Médicament (CERMN, Caen, France) at 10µM. For each compound, the following values are provided: the area under normalised Cell Index curve (AUCn), the %AUCn compared to AUCn of untreated infected cells, the time required for the cell index to decrease by 50 % after virus infection (CIT50) and the ΔCIT50 value obtained by comparing results for treated vs untreated, EHV-1-infected control wells. The Z-factor was used to assess the quality of the screening in 96-well format. For untreated mock-infected and untreated infected cells, the mean ± SD of AUCn is reported. N.D., not determinable.

<table><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUCn</th><th>%AUCn</th><th>CIT50</th><th>ΔCIT50</th></tr></thead><tbody><tr><td>C01 untreated mock-infected cells</td><td>0.79</td><td>200.89 ± 6.27</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C02 untreated infected cells</td><td>0.79</td><td>51.05 ± 4.22</td><td>N.D</td><td>44:33:17</td><td>N.D</td></tr><tr><td>CEmr-2967200</td><td>0.79</td><td>56.69</td><td>11.07</td><td>48:39:22</td><td>8.10</td></tr><tr><td>CESr-2708000</td><td>0.79</td><td>52.15</td><td>2.16</td><td>38:48:07</td><td>-1.75</td></tr><tr><td>CEmr-1642100</td><td>0.79</td><td>39.72</td><td>-22.19</td><td>39:29:39</td><td>-1.06</td></tr><tr><td>CESr-2713000</td><td>0.79</td><td>55.45</td><td>8.63</td><td>35:57:21</td><td>-4.60</td></tr><tr><td>CESr-2704000</td><td>0.79</td><td>46.67</td><td>-8.72</td><td>37:15:38</td><td>-3.29</td></tr><tr><td>CEmr-1506400</td><td>0.79</td><td>48.37</td><td>-5.25</td><td>36:36:37</td><td>-3.94</td></tr><tr><td>CESr-2036000</td><td>0.79</td><td>43.53</td><td>-14.72</td><td>36:56:02</td><td>-3.62</td></tr><tr><td>CESr-4857000</td><td>0.79</td><td>52.24</td><td>2.34</td><td>39:12:32</td><td>-1.35</td></tr><tr><td>CESr-4858000</td><td>0.79</td><td>47.02</td><td>-7.90</td><td>35:59:38</td><td>-4.56</td></tr><tr><td>CESr-4860000</td><td>0.79</td><td>48.96</td><td>-4.09</td><td>37:10:03</td><td>-3.39</td></tr><tr><td>CEmr-2558600</td><td>0.79</td><td>49.41</td><td>-3.21</td><td>38:08:38</td><td>-2.41</td></tr><tr><td>CESr-6941000</td><td>0.79</td><td>46.78</td><td>-8.36</td><td>36:38:04</td><td>-3.92</td></tr><tr><td>CESr-6305000</td><td>0.79</td><td>44.48</td><td>-12.87</td><td>37:47:31</td><td>-2.76</td></tr><tr><td>CESr-6698000</td><td>0.79</td><td>44.33</td><td>-13.17</td><td>35:50:51</td><td>-4.71</td></tr><tr><td>CESr-2564000</td><td>0.79</td><td>44.20</td><td>-13.41</td><td>34:46:48</td><td>-5.77</td></tr><tr><td>CEmr-2242400</td><td>0.79</td><td>63.72</td><td>24.82</td><td>43:21:50</td><td>2.81</td></tr><tr><td>CEmr-2693000</td><td>0.79</td><td>52.83</td><td>3.49</td><td>38:37:51</td><td>-1.92</td></tr><tr><td>CEmr-2577700</td><td>0.79</td><td>53.33</td><td>4.47</td><td>40:23:24</td><td>-0.16</td></tr><tr><td>CEmr-2242100</td><td>0.79</td><td>54.45</td><td>6.67</td><td>39:09:09</td><td>-1.40</td></tr><tr><td>CEmr-3182300</td><td>0.79</td><td>50.08</td><td>-1.90</td><td>34:51:04</td><td>-5.70</td></tr><tr><td>CEmr-3069500</td><td>0.79</td><td>43.52</td><td>-14.75</td><td>35:22:53</td><td>-5.17</td></tr><tr><td>CEmr-3069600</td><td>0.79</td><td>51.01</td><td>-0.08</td><td>42:37:14</td><td>2.07</td></tr><tr><td>CEmr-3068600</td><td>0.79</td><td>33.97</td><td>-33.44</td><td>40:06:15</td><td>-0.45</td></tr><tr><td>CESr-5054000</td><td>0.79</td><td>52.80</td><td>3.44</td><td>42:24:57</td><td>1.86</td></tr><tr><td>CESr-2719000</td><td>0.79</td><td>56.08</td><td>9.85</td><td>41:18:31</td><td>0.75</td></tr><tr><td>CESr-1342000</td><td>0.79</td><td>63.70</td><td>24.79</td><td>40:25:46</td><td>-0.13</td></tr><tr><td>CESr-4369000</td><td>0.79</td><td>58.90</td><td>15.39</td><td>38:35:06</td><td>-1.97</td></tr><tr><td>CESr-7174000</td><td>0.79</td><td>50.34</td><td>-1.38</td><td>42:41:45</td><td>2.14</td></tr><tr><td>CESr-7401000</td><td>0.79</td><td>45.89</td><td>-10.10</td><td>36:40:35</td><td>-3.88</td></tr><tr><td>CESr-6415000</td><td>0.79</td><td>40.92</td><td>-19.84</td><td>37:33:34</td><td>-3.00</td></tr><tr><td>CESr-5002000</td><td>0.79</td><td>49.14</td><td>-3.74</td><td>38:55:38</td><td>-1.63</td></tr><tr><td>CEmr-2502000</td><td>0.79</td><td>63.05</td><td>23.51</td><td>43:14:07</td><td>2.68</td></tr><tr><td>CESr-2566000</td><td>0.79</td><td>53.90</td><td>5.59</td><td>42:18:19</td><td>1.75</td></tr><tr><td>CESr-2551000</td><td>0.79</td><td>48.42</td><td>-5.15</td><td>39:47:43</td><td>-0.76</td></tr><tr><td>CESr-2544000</td><td>0.79</td><td>43.63</td><td>-14.52</td><td>34:49:23</td><td>-5.73</td></tr><tr><td>CESr-6413000</td><td>0.79</td><td>44.91</td><td>-12.02</td><td>36:09:32</td><td>-4.40</td></tr><tr><td>CEmr-2870400</td><td>0.79</td><td>48.05</td><td>-5.87</td><td>38:41:06</td><td>-1.87</td></tr><tr><td>CEmr-2601100</td><td>0.79</td><td>40.93</td><td>-19.82</td><td>36:50:42</td><td>-3.71</td></tr><tr><td>CESr-1038000</td><td>0.79</td><td>60.27</td><td>18.06</td><td>39:46:43</td><td>-0.78</td></tr><tr><td>CESr-1308000</td><td>0.79</td><td>40.11</td><td>-21.43</td><td>14:38:13</td><td>-25.92</td></tr><tr><td>CESr-4292000</td><td>0.79</td><td>47.61</td><td>-6.74</td><td>36:20:51</td><td>-4.21</td></tr><tr><td>CESr-4896000</td><td>0.79</td><td>52.33</td><td>2.51</td><td>37:03:48</td><td>-3.49</td></tr><tr><td>CESr-4204000</td><td>0.79</td><td>42.26</td><td>-17.22</td><td>36:07:04</td><td>-4.44</td></tr><tr><td>CEmr-3132500</td><td>0.79</td><td>44.51</td><td>-12.80</td><td>35:58:10</td><td>-4.59</td></tr><tr><td>CEmr-2570900</td><td>0.79</td><td>43.35</td><td>-15.08</td><td>36:36:36</td><td>-3.94</td></tr><tr><td>CEmr-1729400</td><td>0.79</td><td>49.42</td><td>-3.18</td><td>36:57:57</td><td>-3.59</td></tr><tr><td>CEmr-3181200</td><td>0.79</td><td>44.23</td><td>-13.35</td><td>38:34:10</td><td>-1.99</td></tr><tr><td>CESr-5549000</td><td>0.79</td><td>63.74</td><td>24.87</td><td>40:06:23</td><td>-0.45</td></tr><tr><td>CEmr-2394700</td><td>0.79</td><td>51.17</td><td>0.24</td><td>39:55:28</td><td>-0.63</td></tr><tr><td>CESr-3090000</td><td>0.79</td><td>48.33</td><td>-5.32</td><td>37:44:08</td><td>-2.82</td></tr><tr><td>CESr-6822000</td><td>0.79</td><td>44.49</td><td>-12.85</td><td>35:18:37</td><td>-5.24</td></tr><tr><td>CEmr-1920800</td><td>0.79</td><td>46.05</td><td>-9.78</td><td>37:43:17</td><td>-2.83</td></tr><tr><td>CEmr-1513300</td><td>0.79</td><td>42.29</td><td>-17.16</td><td>35:02:13</td><td>-5.52</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEsr-4726000</td><td>0.79</td><td>46.24</td><td>-9.41</td><td>35:58:18</td><td>-4.58</td></tr><tr><td>CEmr-1457400</td><td>0.79</td><td>50.74</td><td>-0.60</td><td>37:28:11</td><td>-3.08</td></tr><tr><td>CEsr-4650000</td><td>0.79</td><td>55.51</td><td>8.74</td><td>40:43:20</td><td>0.17</td></tr><tr><td>CEsr-6179000</td><td>0.79</td><td>56.03</td><td>9.76</td><td>39:14:55</td><td>-1.31</td></tr><tr><td>CEmr-2552200</td><td>0.79</td><td>51.47</td><td>0.83</td><td>37:17:46</td><td>-3.26</td></tr><tr><td>CEsr-7571000</td><td>0.79</td><td>27.25</td><td>-46.62</td><td>20:13:52</td><td>-20.32</td></tr><tr><td>CEsr-4882000</td><td>0.79</td><td>51.60</td><td>1.09</td><td>37:15:03</td><td>-3.30</td></tr><tr><td>CEsr-4879000</td><td>0.79</td><td>48.65</td><td>-4.69</td><td>36:59:24</td><td>-3.56</td></tr><tr><td>CEmr-2300900</td><td>0.79</td><td>55.73</td><td>9.18</td><td>37:13:41</td><td>-3.33</td></tr><tr><td>CEsr-5700000</td><td>0.79</td><td>54.11</td><td>6.00</td><td>39:48:19</td><td>-0.75</td></tr><tr><td>CEsr-2586800</td><td>0.79</td><td>63.18</td><td>23.77</td><td>42:59:43</td><td>2.44</td></tr><tr><td>CEmr-2778300</td><td>0.79</td><td>56.78</td><td>11.24</td><td>37:50:50</td><td>-2.71</td></tr><tr><td>CEsr-6469000</td><td>0.79</td><td>61.87</td><td>21.21</td><td>44:39:04</td><td>4.10</td></tr><tr><td>CEmr-1812200</td><td>0.79</td><td>56.76</td><td>11.19</td><td>38:31:24</td><td>-2.03</td></tr><tr><td>CEsr-6818000</td><td>0.79</td><td>59.06</td><td>15.70</td><td>40:26:12</td><td>-0.12</td></tr><tr><td>CEsr-4888000</td><td>0.79</td><td>43.02</td><td>-15.72</td><td>34:04:00</td><td>-6.49</td></tr><tr><td>CEmr-2512300</td><td>0.79</td><td>46.01</td><td>-9.86</td><td>37:45:17</td><td>-2.80</td></tr><tr><td>CEmr-3115100</td><td>0.79</td><td>53.23</td><td>4.21</td><td>41:16:17</td><td>0.72</td></tr><tr><td>CEsr-6001000</td><td>0.79</td><td>50.86</td><td>-0.36</td><td>38:38:41</td><td>-1.91</td></tr><tr><td>CEsr-5875000</td><td>0.79</td><td>53.20</td><td>4.22</td><td>36:55:13</td><td>-3.63</td></tr><tr><td>CEsr-5519000</td><td>0.79</td><td>56.73</td><td>11.13</td><td>36:18:41</td><td>-4.24</td></tr><tr><td>CEmr-1329700</td><td>0.79</td><td>57.09</td><td>11.85</td><td>38:18:43</td><td>-2.24</td></tr><tr><td>CEmr-1457700</td><td>0.79</td><td>54.98</td><td>7.71</td><td>37:34:28</td><td>-2.98</td></tr><tr><td>CEsr-7263000</td><td>0.79</td><td>54.95</td><td>7.65</td><td>39:02:18</td><td>-1.52</td></tr><tr><td>CEsr-4898000</td><td>0.79</td><td>52.49</td><td>2.83</td><td>36:40:49</td><td>-3.87</td></tr><tr><td>CEmr-2553000</td><td>0.79</td><td>56.68</td><td>11.03</td><td>39:39:55</td><td>-0.89</td></tr><tr><td>CEsr-1943500</td><td>0.79</td><td>49.36</td><td>-3.31</td><td>37:41:09</td><td>-2.87</td></tr><tr><td>C02 untreated mock-infected cells</td><td>0.878037237</td><td>202.44 ± 2.58</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C02 untreated infected cells</td><td>0.88</td><td>48.35 ± 3.69</td><td>N.D</td><td>36:51:03</td><td>N.D</td></tr><tr><td>CEsr-3085000</td><td>0.88</td><td>60.77</td><td>25.69</td><td>39:57:43</td><td>3.11</td></tr><tr><td>CEmr-2558400</td><td>0.88</td><td>54.15</td><td>12.00</td><td>40:16:44</td><td>3.43</td></tr><tr><td>CEsr-5906000</td><td>0.88</td><td>51.04</td><td>5.57</td><td>40:22:53</td><td>3.53</td></tr><tr><td>CEsr-3914000</td><td>0.88</td><td>49.56</td><td>2.51</td><td>35:48:05</td><td>-1.05</td></tr><tr><td>CEsr-4161000</td><td>0.88</td><td>47.91</td><td>-0.91</td><td>39:49:00</td><td>2.97</td></tr><tr><td>CEmr-3137100</td><td>0.88</td><td>51.75</td><td>7.04</td><td>39:27:38</td><td>2.61</td></tr><tr><td>CEsr-5677000</td><td>0.88</td><td>26.91</td><td>-44.33</td><td>39:02:34</td><td>2.19</td></tr><tr><td>CEsr-2541000</td><td>0.88</td><td>51.69</td><td>6.91</td><td>40:22:52</td><td>3.53</td></tr><tr><td>CEsr-1443000</td><td>0.88</td><td>46.54</td><td>-3.73</td><td>37:40:31</td><td>0.82</td></tr><tr><td>CEsr-1286000</td><td>0.88</td><td>49.79</td><td>2.99</td><td>38:18:48</td><td>1.46</td></tr><tr><td>CEsr-2487000</td><td>0.88</td><td>53.01</td><td>9.65</td><td>40:55:53</td><td>4.08</td></tr><tr><td>CEmr-3394000</td><td>0.88</td><td>60.09</td><td>24.29</td><td>41:17:40</td><td>4.44</td></tr><tr><td>CEsr-7181000</td><td>0.88</td><td>45.20</td><td>-6.52</td><td>35:08:23</td><td>-1.71</td></tr><tr><td>CEmr-2362000</td><td>0.88</td><td>51.19</td><td>5.88</td><td>38:31:53</td><td>1.68</td></tr><tr><td>CEsr-2502200</td><td>0.88</td><td>54.54</td><td>12.82</td><td>41:10:11</td><td>4.32</td></tr><tr><td>CEsr-1214000</td><td>0.88</td><td>77.09</td><td>59.46</td><td>40:56:01</td><td>4.08</td></tr><tr><td>CEmr-1813300</td><td>0.88</td><td>60.16</td><td>24.43</td><td>42:10:29</td><td>5.32</td></tr><tr><td>CEsr-4153000</td><td>0.88</td><td>50.79</td><td>5.05</td><td>39:54:15</td><td>3.05</td></tr><tr><td>CEmr-3398000</td><td>0.88</td><td>47.86</td><td>-1.00</td><td>37:54:18</td><td>1.05</td></tr><tr><td>CEsr-1329300</td><td>0.88</td><td>44.66</td><td>-7.63</td><td>36:09:30</td><td>-0.69</td></tr><tr><td>CEsr-2529000</td><td>0.88</td><td>49.23</td><td>1.83</td><td>38:27:46</td><td>1.61</td></tr><tr><td>CEsr-3856000</td><td>0.88</td><td>52.62</td><td>8.84</td><td>39:27:56</td><td>2.61</td></tr><tr><td>CEsr-3654000</td><td>0.88</td><td>52.48</td><td>8.55</td><td>39:37:10</td><td>2.77</td></tr><tr><td>CEmr-1365200</td><td>0.88</td><td>51.46</td><td>6.44</td><td>41:39:58</td><td>4.82</td></tr><tr><td>CEsr-4989000</td><td>0.88</td><td>51.48</td><td>6.48</td><td>38:38:51</td><td>1.80</td></tr><tr><td>CEsr-7295000</td><td>0.88</td><td>56.79</td><td>17.46</td><td>42:48:58</td><td>5.97</td></tr><tr><td>CEsr-4428000</td><td>0.88</td><td>51.04</td><td>5.57</td><td>38:58:56</td><td>2.13</td></tr><tr><td>CEsr-3924000</td><td>0.88</td><td>47.22</td><td>-2.33</td><td>37:41:13</td><td>0.84</td></tr><tr><td>CEsr-2749000</td><td>0.88</td><td>44.26</td><td>-8.45</td><td>37:23:14</td><td>0.54</td></tr><tr><td>CEmr-3189600</td><td>0.88</td><td>32.74</td><td>-32.28</td><td>35:53:18</td><td>-0.96</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEsr-5612000</td><td>0.88</td><td>49.03</td><td>1.41</td><td>36:35:00</td><td>-0.27</td></tr><tr><td>CEsr-1477000</td><td>0.88</td><td>51.69</td><td>6.91</td><td>39:05:07</td><td>2.23</td></tr><tr><td>CEsr-3228000</td><td>0.88</td><td>44.62</td><td>-7.70</td><td>37:15:03</td><td>0.40</td></tr><tr><td>CEsr-5049000</td><td>0.88</td><td>46.91</td><td>-2.96</td><td>40:06:14</td><td>3.25</td></tr><tr><td>CEmr-22848a0</td><td>0.88</td><td>55.30</td><td>14.39</td><td>40:00:00</td><td>3.15</td></tr><tr><td>CEmr-1724100</td><td>0.88</td><td>44.90</td><td>-7.13</td><td>35:22:57</td><td>-1.47</td></tr><tr><td>CEmr-1724000</td><td>0.88</td><td>50.43</td><td>4.32</td><td>38:03:44</td><td>1.21</td></tr><tr><td>CEsr-3207000</td><td>0.88</td><td>51.62</td><td>6.76</td><td>36:52:47</td><td>0.03</td></tr><tr><td>CEmr-1678500</td><td>0.88</td><td>52.38</td><td>8.35</td><td>40:04:20</td><td>3.22</td></tr><tr><td>CEmr-2792400</td><td>0.88</td><td>57.17</td><td>18.26</td><td>42:23:16</td><td>5.54</td></tr><tr><td>CEmr-2872100</td><td>0.88</td><td>44.27</td><td>-8.43</td><td>37:55:52</td><td>1.08</td></tr><tr><td>CEsr-5826000</td><td>0.88</td><td>52.65</td><td>8.91</td><td>37:26:50</td><td>0.60</td></tr><tr><td>CEsr-5804000</td><td>0.88</td><td>47.19</td><td>-2.38</td><td>37:46:45</td><td>0.93</td></tr><tr><td>CEsr-3558000</td><td>0.88</td><td>46.81</td><td>-3.17</td><td>36:28:06</td><td>-0.38</td></tr><tr><td>CEsr-3569000</td><td>0.88</td><td>50.64</td><td>4.74</td><td>38:34:59</td><td>1.73</td></tr><tr><td>CEmr-2325500</td><td>0.88</td><td>58.03</td><td>20.04</td><td>38:23:30</td><td>1.54</td></tr><tr><td>CEsr-5558000</td><td>0.88</td><td>50.58</td><td>4.62</td><td>38:43:28</td><td>1.87</td></tr><tr><td>CEmr-3201900</td><td>0.88</td><td>55.88</td><td>15.58</td><td>40:45:41</td><td>3.91</td></tr><tr><td>CEmr-3093700</td><td>0.88</td><td>54.80</td><td>13.36</td><td>41:18:48</td><td>4.46</td></tr><tr><td>CEsr-5547000</td><td>0.88</td><td>46.33</td><td>-4.17</td><td>36:54:09</td><td>0.05</td></tr><tr><td>CEsr-3437000</td><td>0.88</td><td>44.12</td><td>-8.74</td><td>36:15:37</td><td>-0.59</td></tr><tr><td>CEsr-2333000</td><td>0.88</td><td>47.50</td><td>-1.75</td><td>35:48:02</td><td>-1.05</td></tr><tr><td>CEmr-2387800</td><td>0.88</td><td>44.32</td><td>-8.32</td><td>35:53:58</td><td>-0.95</td></tr><tr><td>CEsr-4918000</td><td>0.88</td><td>51.87</td><td>7.29</td><td>37:12:03</td><td>0.35</td></tr><tr><td>CEmr-2501400</td><td>0.88</td><td>48.02</td><td>-0.68</td><td>38:11:53</td><td>1.35</td></tr><tr><td>CEmr-2876800</td><td>0.88</td><td>55.91</td><td>15.65</td><td>41:26:48</td><td>4.60</td></tr><tr><td>CEsr-1298000</td><td>0.88</td><td>59.10</td><td>22.24</td><td>39:57:36</td><td>3.11</td></tr><tr><td>CEmr-2530500</td><td>0.88</td><td>54.29</td><td>12.30</td><td>40:38:11</td><td>3.79</td></tr><tr><td>CEsr-6975000</td><td>0.88</td><td>47.04</td><td>-2.71</td><td>37:54:38</td><td>1.06</td></tr><tr><td>CEsr-5387000</td><td>0.88</td><td>43.98</td><td>-9.02</td><td>34:54:57</td><td>-1.93</td></tr><tr><td>CEsr-5793000</td><td>0.88</td><td>44.12</td><td>-8.74</td><td>37:14:42</td><td>0.39</td></tr><tr><td>CEsr-5334000</td><td>0.88</td><td>46.12</td><td>-4.60</td><td>35:44:16</td><td>-1.11</td></tr><tr><td>CEmr-2384300</td><td>0.88</td><td>49.18</td><td>1.72</td><td>38:56:40</td><td>2.09</td></tr><tr><td>CEsr-5335000</td><td>0.88</td><td>42.90</td><td>-11.27</td><td>39:01:54</td><td>2.18</td></tr><tr><td>CEmr-2384700</td><td>0.88</td><td>48.19</td><td>-0.32</td><td>38:35:16</td><td>1.74</td></tr><tr><td>CEsr-5398000</td><td>0.88</td><td>48.34</td><td>-0.01</td><td>38:33:12</td><td>1.70</td></tr><tr><td>CEsr-5256000</td><td>0.88</td><td>50.52</td><td>4.51</td><td>37:44:12</td><td>0.89</td></tr><tr><td>CEsr-5265000</td><td>0.88</td><td>44.41</td><td>-8.14</td><td>36:59:02</td><td>0.13</td></tr><tr><td>CEsr-5778000</td><td>0.88</td><td>45.09</td><td>-6.73</td><td>37:15:27</td><td>0.41</td></tr><tr><td>CEmr-1842600</td><td>0.88</td><td>46.13</td><td>-4.58</td><td>38:03:37</td><td>1.21</td></tr><tr><td>CEsr-5294000</td><td>0.88</td><td>43.96</td><td>-9.07</td><td>38:15:44</td><td>1.41</td></tr><tr><td>CEmr-1478200</td><td>0.88</td><td>48.46</td><td>0.24</td><td>40:42:36</td><td>3.86</td></tr><tr><td>CEmr-2108500</td><td>0.88</td><td>46.06</td><td>-4.73</td><td>37:42:10</td><td>0.85</td></tr><tr><td>CEmr-1845900</td><td>0.88</td><td>50.63</td><td>4.73</td><td>39:52:53</td><td>3.03</td></tr><tr><td>CEmr-1676800</td><td>0.88</td><td>48.29</td><td>-0.11</td><td>37:51:21</td><td>1.01</td></tr><tr><td>CEsr-5295000</td><td>0.88</td><td>44.10</td><td>-8.78</td><td>36:29:11</td><td>-0.36</td></tr><tr><td>CEmr-2503400</td><td>0.88</td><td>52.94</td><td>9.50</td><td>41:34:31</td><td>4.72</td></tr><tr><td>CEsr-7169000</td><td>0.88</td><td>31.79</td><td>34.25</td><td>40:28:51</td><td>3.63</td></tr><tr><td>CEmr-2707200</td><td>0.88</td><td>50.02</td><td>3.47</td><td>37:53:27</td><td>1.04</td></tr><tr><td>CEmr-3139400</td><td>0.88</td><td>46.43</td><td>-3.97</td><td>38:18:49</td><td>1.46</td></tr><tr><td>C03 untreated mock-infected cells</td><td>0.65560864</td><td>212.29 ± 15.22</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C03 untreated infected cells</td><td>0.66</td><td>46.67 ± 3.79</td><td>N.D</td><td>37:28:10</td><td>N.D</td></tr><tr><td>CEmr-2812000</td><td>0.66</td><td>51.15</td><td>9.59</td><td>39:30:41</td><td>2.04</td></tr><tr><td>CEsr-4893000</td><td>0.66</td><td>47.74</td><td>2.28</td><td>36:30:53</td><td>-0.95</td></tr><tr><td>CEsr-2108000</td><td>0.66</td><td>43.89</td><td>-5.97</td><td>38:57:24</td><td>1.49</td></tr><tr><td>CEsr-6198000</td><td>0.66</td><td>44.34</td><td>-5.00</td><td>35:48:23</td><td>-1.66</td></tr><tr><td>CEmr-1506300</td><td>0.66</td><td>50.25</td><td>7.66</td><td>36:44:12</td><td>-0.73</td></tr><tr><td>CEmr-2552300</td><td>0.66</td><td>50.84</td><td>8.92</td><td>37:28:26</td><td>0.00</td></tr><tr><td>CEmr-1848100</td><td>0.66</td><td>46.67</td><td>0.00</td><td>36:59:01</td><td>-0.49</td></tr><tr><td>CEmr-3228900</td><td>0.66</td><td>39.85</td><td>-14.61</td><td>35:58:52</td><td>-1.49</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEmr-3181300</td><td>0.66</td><td>46.07</td><td>-1.30</td><td>46:51:59</td><td>9.40</td></tr><tr><td>CEsr-5350000</td><td>0.66</td><td>39.82</td><td>-14.68</td><td>35:23:20</td><td>-2.08</td></tr><tr><td>CEsr-2136000</td><td>0.66</td><td>48.34</td><td>3.57</td><td>39:42:25</td><td>2.24</td></tr><tr><td>CEmr-2984900</td><td>0.66</td><td>44.86</td><td>-3.88</td><td>36:32:29</td><td>-0.93</td></tr><tr><td>CEsr-7527000</td><td>0.66</td><td>47.16</td><td>1.04</td><td>36:13:08</td><td>-1.25</td></tr><tr><td>CEsr-5626000</td><td>0.66</td><td>47.62</td><td>2.02</td><td>36:58:33</td><td>-0.49</td></tr><tr><td>CEmr-2134200</td><td>0.66</td><td>66.37</td><td>42.20</td><td>42:16:45</td><td>4.81</td></tr><tr><td>CEsr-1724000</td><td>0.66</td><td>50.65</td><td>8.52</td><td>38:19:58</td><td>0.86</td></tr><tr><td>CEsr-5000000</td><td>0.66</td><td>38.65</td><td>-17.20</td><td>39:41:42</td><td>2.23</td></tr><tr><td>CEsr-2123000</td><td>0.66</td><td>50.21</td><td>7.57</td><td>39:38:37</td><td>2.17</td></tr><tr><td>CEsr-1686000</td><td>0.66</td><td>51.66</td><td>10.68</td><td>38:44:13</td><td>1.27</td></tr><tr><td>CEmr-2758700</td><td>0.66</td><td>46.64</td><td>-0.07</td><td>37:13:59</td><td>-0.24</td></tr><tr><td>CEsr-6220000</td><td>0.66</td><td>51.83</td><td>11.04</td><td>36:44:55</td><td>-0.72</td></tr><tr><td>CEmr-2987700</td><td>0.66</td><td>46.49</td><td>-0.40</td><td>36:14:53</td><td>-1.22</td></tr><tr><td>CEsr-3385000</td><td>0.66</td><td>47.80</td><td>2.41</td><td>40:05:44</td><td>2.63</td></tr><tr><td>CEmr-3391600</td><td>0.66</td><td>46.38</td><td>-0.64</td><td>38:58:29</td><td>1.51</td></tr><tr><td>CEmr-3392600</td><td>0.66</td><td>47.86</td><td>2.55</td><td>39:15:44</td><td>1.79</td></tr><tr><td>CEsr-1427000</td><td>0.66</td><td>50.15</td><td>7.45</td><td>38:29:52</td><td>1.03</td></tr><tr><td>CEsr-7085000</td><td>0.66</td><td>32.08</td><td>-31.27</td><td>36:02:08</td><td>-1.43</td></tr><tr><td>CEsr-7341000</td><td>0.66</td><td>48.66</td><td>4.26</td><td>37:43:54</td><td>0.26</td></tr><tr><td>CEsr-1114000</td><td>0.66</td><td>48.16</td><td>3.18</td><td>38:02:25</td><td>0.57</td></tr><tr><td>CEmr-2558800</td><td>0.66</td><td>42.82</td><td>-8.26</td><td>37:50:49</td><td>0.38</td></tr><tr><td>CEmr-1728800</td><td>0.66</td><td>47.24</td><td>1.21</td><td>39:40:58</td><td>2.21</td></tr><tr><td>CEmr-2661700</td><td>0.66</td><td>58.69</td><td>25.74</td><td>53:14:07</td><td>15.77</td></tr><tr><td>CEmr-2034000</td><td>0.66</td><td>53.74</td><td>15.14</td><td>38:37:11</td><td>1.15</td></tr><tr><td>CEsr-5410000</td><td>0.66</td><td>52.85</td><td>13.23</td><td>39:00:43</td><td>1.54</td></tr><tr><td>CEsr-5422000</td><td>0.66</td><td>41.23</td><td>-11.66</td><td>36:17:31</td><td>-1.18</td></tr><tr><td>CEsr-4265000</td><td>0.66</td><td>41.88</td><td>-10.26</td><td>35:13:05</td><td>-2.25</td></tr><tr><td>CEsr-6644000</td><td>0.66</td><td>46.27</td><td>-0.87</td><td>35:32:39</td><td>-1.93</td></tr><tr><td>CEsr-6642000</td><td>0.66</td><td>46.51</td><td>-0.36</td><td>37:51:41</td><td>0.39</td></tr><tr><td>CEsr-4254000</td><td>0.66</td><td>39.82</td><td>-14.69</td><td>39:40:40</td><td>2.21</td></tr><tr><td>CEsr-6625000</td><td>0.66</td><td>50.19</td><td>7.54</td><td>38:20:58</td><td>0.88</td></tr><tr><td>CEmr-2811100</td><td>0.66</td><td>46.07</td><td>-1.29</td><td>37:32:10</td><td>0.07</td></tr><tr><td>CEmr-2033500</td><td>0.66</td><td>51.51</td><td>10.37</td><td>38:45:53</td><td>1.30</td></tr><tr><td>CEmr-1813200</td><td>0.66</td><td>45.47</td><td>-2.58</td><td>39:50:42</td><td>2.38</td></tr><tr><td>CEmr-1540700</td><td>0.66</td><td>41.19</td><td>-11.75</td><td>34:31:55</td><td>-2.94</td></tr><tr><td>CEmr-1320400</td><td>0.66</td><td>47.74</td><td>2.28</td><td>36:27:18</td><td>-1.01</td></tr><tr><td>CEmr-2299400</td><td>0.66</td><td>46.60</td><td>-0.16</td><td>36:39:44</td><td>-0.81</td></tr><tr><td>CEmr-2397300</td><td>0.66</td><td>45.62</td><td>-2.27</td><td>35:51:30</td><td>-1.61</td></tr><tr><td>CEsr-5770000</td><td>0.66</td><td>52.96</td><td>13.48</td><td>39:47:11</td><td>2.32</td></tr><tr><td>CEsr-2916000</td><td>0.66</td><td>49.67</td><td>6.41</td><td>39:11:12</td><td>1.72</td></tr><tr><td>CEsr-2923000</td><td>0.66</td><td>51.46</td><td>10.25</td><td>37:57:02</td><td>0.48</td></tr><tr><td>CEsr-4948000</td><td>0.66</td><td>50.40</td><td>7.99</td><td>38:35:15</td><td>1.12</td></tr><tr><td>CEsr-7395000</td><td>0.66</td><td>49.33</td><td>5.68</td><td>36:28:11</td><td>-1.00</td></tr><tr><td>CEsr-1403000</td><td>0.66</td><td>48.89</td><td>4.75</td><td>39:50:06</td><td>2.37</td></tr><tr><td>CEsr-1442000</td><td>0.66</td><td>42.58</td><td>-8.76</td><td>37:24:46</td><td>-0.06</td></tr><tr><td>CEsr-5246000</td><td>0.66</td><td>53.07</td><td>13.70</td><td>38:21:15</td><td>0.88</td></tr><tr><td>CEmr-2401700</td><td>0.66</td><td>50.92</td><td>9.11</td><td>36:59:41</td><td>-0.47</td></tr><tr><td>CEmr-2874600</td><td>0.66</td><td>42.64</td><td>-8.64</td><td>40:18:53</td><td>2.85</td></tr><tr><td>CEmr-2092800</td><td>0.66</td><td>45.54</td><td>-2.44</td><td>38:03:00</td><td>0.58</td></tr><tr><td>CEsr-1413000</td><td>0.66</td><td>36.25</td><td>-22.34</td><td>35:39:16</td><td>-1.81</td></tr><tr><td>CEmr-2381100</td><td>0.66</td><td>49.98</td><td>7.08</td><td>38:04:41</td><td>0.61</td></tr><tr><td>CEsr-7400000</td><td>0.66</td><td>44.89</td><td>-3.82</td><td>37:50:35</td><td>0.37</td></tr><tr><td>CEsr-1462000</td><td>0.66</td><td>37.36</td><td>-19.95</td><td>38:01:20</td><td>0.55</td></tr><tr><td>CEmr-2093600</td><td>0.66</td><td>47.86</td><td>2.54</td><td>37:12:56</td><td>-0.25</td></tr><tr><td>CEsr-5223000</td><td>0.66</td><td>52.23</td><td>11.90</td><td>38:23:37</td><td>0.92</td></tr><tr><td>CEsr-1215000</td><td>0.66</td><td>46.09</td><td>-1.26</td><td>37:53:46</td><td>0.43</td></tr><tr><td>CEsr-1287000</td><td>0.66</td><td>47.52</td><td>1.82</td><td>37:45:03</td><td>0.28</td></tr><tr><td>CEsr-7195000</td><td>0.66</td><td>44.76</td><td>-4.11</td><td>37:54:10</td><td>0.43</td></tr><tr><td>CEmr-2382500</td><td>0.66</td><td>44.07</td><td>-5.58</td><td>37:41:41</td><td>0.23</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CESr-5231000</td><td>0.66</td><td>54.22</td><td>16.17</td><td>40:11:39</td><td>2.72</td></tr><tr><td>CESr-7403000</td><td>0.66</td><td>49.33</td><td>5.70</td><td>38:31:56</td><td>1.06</td></tr><tr><td>CEmr-2890400</td><td>0.66</td><td>49.21</td><td>5.44</td><td>37:22:17</td><td>-0.10</td></tr><tr><td>CESr-1680000</td><td>0.66</td><td>53.92</td><td>15.53</td><td>38:56:24</td><td>1.47</td></tr><tr><td>CESr-2873000</td><td>0.66</td><td>46.80</td><td>0.27</td><td>36:12:46</td><td>-1.26</td></tr><tr><td>CESr-7255000</td><td>0.66</td><td>52.70</td><td>12.92</td><td>37:37:45</td><td>0.16</td></tr><tr><td>CESr-6770000</td><td>0.66</td><td>61.14</td><td>31.00</td><td>47:14:54</td><td>9.78</td></tr><tr><td>CESr-2835000</td><td>0.66</td><td>48.18</td><td>3.22</td><td>37:53:21</td><td>0.42</td></tr><tr><td>CESr-2851000</td><td>0.66</td><td>62.68</td><td>34.28</td><td>37:23:37</td><td>-0.08</td></tr><tr><td>CESr-7333000</td><td>0.66</td><td>45.03</td><td>-3.52</td><td>38:52:06</td><td>1.40</td></tr><tr><td>CESr-6778000</td><td>0.66</td><td>49.84</td><td>6.78</td><td>38:17:08</td><td>0.82</td></tr><tr><td>CESr-4644000</td><td>0.66</td><td>54.80</td><td>17.40</td><td>39:46:02</td><td>2.30</td></tr><tr><td>C04 untreated mock-infected cells</td><td>0.86</td><td>183.90 ± 5.87</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C04 untreated infected cells</td><td>0.86</td><td>38.23 ± 1.1</td><td>N.D</td><td>36:31:32</td><td>N.D</td></tr><tr><td>CESr-3921000</td><td>0.86</td><td>53.65</td><td>40.33</td><td>47:08:49</td><td>10.62</td></tr><tr><td>CEmr-3153200</td><td>0.86</td><td>48.65</td><td>27.26</td><td>42:26:50</td><td>5.92</td></tr><tr><td>CESr-5997000</td><td>0.86</td><td>48.75</td><td>27.51</td><td>42:22:44</td><td>5.85</td></tr><tr><td>CESr-4082000</td><td>0.86</td><td>43.69</td><td>14.27</td><td>37:26:24</td><td>0.91</td></tr><tr><td>CEmr-2141200</td><td>0.86</td><td>44.90</td><td>17.45</td><td>38:43:59</td><td>2.21</td></tr><tr><td>CEmr-3135600</td><td>0.86</td><td>44.90</td><td>17.44</td><td>38:52:23</td><td>2.35</td></tr><tr><td>CESr-4551000</td><td>0.86</td><td>49.32</td><td>29.00</td><td>42:12:31</td><td>5.68</td></tr><tr><td>CESr-4850000</td><td>0.86</td><td>46.69</td><td>22.11</td><td>42:34:06</td><td>6.04</td></tr><tr><td>CEmr-3390400</td><td>0.86</td><td>50.00</td><td>30.79</td><td>41:39:57</td><td>5.14</td></tr><tr><td>CEmr-3354200</td><td>0.86</td><td>51.00</td><td>33.41</td><td>40:53:59</td><td>4.37</td></tr><tr><td>CESr-6645000</td><td>0.86</td><td>53.53</td><td>40.01</td><td>41:06:07</td><td>4.58</td></tr><tr><td>CEmr-2983500</td><td>0.86</td><td>55.36</td><td>44.79</td><td>43:47:42</td><td>7.27</td></tr><tr><td>CEmr-3353000</td><td>0.86</td><td>49.22</td><td>28.75</td><td>41:11:19</td><td>4.66</td></tr><tr><td>CEmr-3351300</td><td>0.86</td><td>51.73</td><td>35.30</td><td>44:49:39</td><td>8.30</td></tr><tr><td>CESr-2038000</td><td>0.86</td><td>47.17</td><td>23.39</td><td>39:24:32</td><td>2.88</td></tr><tr><td>CESr-7421000</td><td>0.86</td><td>49.28</td><td>28.91</td><td>43:27:48</td><td>6.94</td></tr><tr><td>CESr-2351000</td><td>0.86</td><td>48.92</td><td>27.95</td><td>42:22:58</td><td>5.86</td></tr><tr><td>CEmr-1671600</td><td>0.86</td><td>53.16</td><td>39.04</td><td>45:19:45</td><td>8.80</td></tr><tr><td>CEmr-1678000</td><td>0.86</td><td>52.33</td><td>36.89</td><td>42:33:55</td><td>6.04</td></tr><tr><td>CESr-2703000</td><td>0.86</td><td>52.29</td><td>36.77</td><td>42:15:48</td><td>5.74</td></tr><tr><td>CESr-2350000</td><td>0.86</td><td>50.91</td><td>33.16</td><td>41:53:22</td><td>5.36</td></tr><tr><td>CESr-7385000</td><td>0.86</td><td>50.82</td><td>32.92</td><td>41:37:20</td><td>5.10</td></tr><tr><td>CEmr-1679200</td><td>0.86</td><td>47.44</td><td>24.08</td><td>40:07:30</td><td>3.60</td></tr><tr><td>CEmr-2102700</td><td>0.86</td><td>46.27</td><td>21.04</td><td>41:23:45</td><td>4.87</td></tr><tr><td>CEmr-8245000</td><td>0.86</td><td>37.91</td><td>-0.84</td><td>39:30:51</td><td>2.99</td></tr><tr><td>CESr-5622000</td><td>0.86</td><td>50.16</td><td>31.21</td><td>39:50:17</td><td>3.31</td></tr><tr><td>CEmr-1678100</td><td>0.86</td><td>48.64</td><td>27.22</td><td>40:36:55</td><td>4.09</td></tr><tr><td>CESr-2620000</td><td>0.86</td><td>39.93</td><td>4.45</td><td>39:12:33</td><td>2.68</td></tr><tr><td>CESr-2619000</td><td>0.86</td><td>53.69</td><td>40.42</td><td>42:20:42</td><td>5.82</td></tr><tr><td>CESr-2971000</td><td>0.86</td><td>51.24</td><td>34.03</td><td>39:10:41</td><td>2.65</td></tr><tr><td>CESr-7372000</td><td>0.86</td><td>45.34</td><td>18.58</td><td>39:58:23</td><td>3.45</td></tr><tr><td>CEmr-2340900</td><td>0.86</td><td>51.75</td><td>35.37</td><td>43:27:27</td><td>6.93</td></tr><tr><td>CEmr-1676700</td><td>0.86</td><td>41.39</td><td>8.27</td><td>40:59:16</td><td>4.46</td></tr><tr><td>CESr-7383000</td><td>0.86</td><td>45.28</td><td>18.44</td><td>40:22:51</td><td>3.86</td></tr><tr><td>CESr-5744000</td><td>0.86</td><td>49.05</td><td>28.31</td><td>43:13:36</td><td>6.70</td></tr><tr><td>CESr-1817000</td><td>0.86</td><td>46.30</td><td>21.11</td><td>42:42:57</td><td>6.19</td></tr><tr><td>CEmr-2584100</td><td>0.86</td><td>49.17</td><td>28.61</td><td>42:37:00</td><td>6.09</td></tr><tr><td>CEmr-2391500</td><td>0.86</td><td>52.73</td><td>37.93</td><td>41:50:52</td><td>5.32</td></tr><tr><td>CEmr-2391600</td><td>0.86</td><td>45.49</td><td>18.98</td><td>38:46:45</td><td>2.25</td></tr><tr><td>CESr-1520000</td><td>0.86</td><td>55.51</td><td>45.18</td><td>44:34:34</td><td>8.05</td></tr><tr><td>CESr-1721000</td><td>0.86</td><td>41.45</td><td>8.41</td><td>38:24:09</td><td>1.88</td></tr><tr><td>CEmr-1448100</td><td>0.86</td><td>45.97</td><td>20.25</td><td>45:13:19</td><td>8.70</td></tr><tr><td>CESr-3830000</td><td>0.86</td><td>42.24</td><td>10.48</td><td>39:14:33</td><td>2.72</td></tr><tr><td>CESr-1528000</td><td>0.86</td><td>43.19</td><td>12.96</td><td>38:47:05</td><td>2.26</td></tr><tr><td>CESr-5508000</td><td>0.86</td><td>45.56</td><td>19.16</td><td>40:39:07</td><td>4.13</td></tr><tr><td>CEmr-2506800</td><td>0.86</td><td>51.98</td><td>35.97</td><td>44:55:16</td><td>8.40</td></tr><tr><td>CESr-1564000</td><td>0.86</td><td>45.91</td><td>20.08</td><td>39:37:06</td><td>3.09</td></tr><tr><td>CESr-5031000</td><td>0.86</td><td>47.79</td><td>25.01</td><td>41:19:03</td><td>4.79</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEsr-4914000</td><td>0.86</td><td>44.25</td><td>15.73</td><td>39:01:50</td><td>2.50</td></tr><tr><td>CEsr-3906000</td><td>0.86</td><td>45.06</td><td>17.87</td><td>40:49:04</td><td>4.29</td></tr><tr><td>CEsr-2175000</td><td>0.86</td><td>36.52</td><td>-4.47</td><td>37:44:04</td><td>1.21</td></tr><tr><td>CEsr-1627000</td><td>0.86</td><td>59.88</td><td>56.64</td><td>45:37:34</td><td>9.10</td></tr><tr><td>CEsr-3936000</td><td>0.86</td><td>45.30</td><td>18.49</td><td>40:22:46</td><td>3.85</td></tr><tr><td>CEsr-3947000</td><td>0.86</td><td>45.06</td><td>17.87</td><td>40:54:53</td><td>4.39</td></tr><tr><td>CEsr-2231700</td><td>0.86</td><td>51.44</td><td>34.54</td><td>43:46:04</td><td>7.24</td></tr><tr><td>CEsr-2501700</td><td>0.86</td><td>44.65</td><td>16.79</td><td>41:17:54</td><td>4.77</td></tr><tr><td>CEsr-3929000</td><td>0.86</td><td>41.66</td><td>8.98</td><td>39:40:27</td><td>3.15</td></tr><tr><td>CEsr-1639000</td><td>0.86</td><td>51.25</td><td>34.05</td><td>39:57:28</td><td>3.43</td></tr><tr><td>CEsr-1601000</td><td>0.86</td><td>50.22</td><td>31.36</td><td>40:18:26</td><td>3.78</td></tr><tr><td>CEsr-1632500</td><td>0.86</td><td>40.14</td><td>5.00</td><td>38:23:53</td><td>1.87</td></tr><tr><td>CEsr-5377000</td><td>0.86</td><td>42.86</td><td>12.11</td><td>38:28:20</td><td>1.95</td></tr><tr><td>CEsr-1607500</td><td>0.86</td><td>48.73</td><td>27.45</td><td>42:09:26</td><td>5.63</td></tr><tr><td>CEsr-1646000</td><td>0.86</td><td>47.45</td><td>24.11</td><td>39:43:48</td><td>3.20</td></tr><tr><td>CEsr-2301000</td><td>0.86</td><td>45.53</td><td>19.10</td><td>38:58:53</td><td>2.46</td></tr><tr><td>CEsr-2503300</td><td>0.86</td><td>61.15</td><td>59.94</td><td>51:04:54</td><td>14.56</td></tr><tr><td>CEsr-2036400</td><td>0.86</td><td>47.80</td><td>25.03</td><td>40:55:02</td><td>4.39</td></tr><tr><td>CEsr-1389700</td><td>0.86</td><td>39.00</td><td>2.01</td><td>37:11:27</td><td>0.67</td></tr><tr><td>CEsr-1161000</td><td>0.86</td><td>47.80</td><td>25.02</td><td>42:07:58</td><td>5.61</td></tr><tr><td>CEsr-3189500</td><td>0.86</td><td>29.91</td><td>-21.76</td><td>8:39:22</td><td>-27.87</td></tr><tr><td>CEsr-2810300</td><td>0.86</td><td>42.07</td><td>10.03</td><td>39:29:02</td><td>2.96</td></tr><tr><td>CEsr-6659000</td><td>0.86</td><td>47.40</td><td>23.98</td><td>45:24:39</td><td>8.89</td></tr><tr><td>CEsr-1143000</td><td>0.86</td><td>42.46</td><td>11.06</td><td>40:57:04</td><td>4.43</td></tr><tr><td>CEsr-1810200</td><td>0.86</td><td>35.65</td><td>-6.76</td><td>38:55:11</td><td>2.39</td></tr><tr><td>CEsr-2870600</td><td>0.86</td><td>48.24</td><td>26.18</td><td>42:32:48</td><td>6.02</td></tr><tr><td>CEsr-1713700</td><td>0.86</td><td>47.09</td><td>23.18</td><td>40:01:55</td><td>3.51</td></tr><tr><td>CEsr-1119000</td><td>0.86</td><td>46.77</td><td>22.33</td><td>42:49:44</td><td>6.30</td></tr><tr><td>CEsr-3220400</td><td>0.86</td><td>40.31</td><td>5.43</td><td>35:43:46</td><td>-0.80</td></tr><tr><td>CEsr-7431000</td><td>0.86</td><td>44.45</td><td>16.26</td><td>42:13:40</td><td>5.70</td></tr><tr><td>CEsr-1158000</td><td>0.86</td><td>45.34</td><td>18.60</td><td>42:30:42</td><td>5.99</td></tr><tr><td>CEsr-6547000</td><td>0.86</td><td>40.05</td><td>4.76</td><td>41:01:25</td><td>4.50</td></tr><tr><td>C05 untreated mock-infected cells</td><td>0.814647679</td><td>190.37 ± 6.24</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C05 untreated infected cells</td><td>0.81</td><td>52.68 ± 2.27</td><td>N.D</td><td>38:40:55</td><td>N.D</td></tr><tr><td>CEsr-7478000</td><td>0.81</td><td>43.45</td><td>-17.52</td><td>40:50:13</td><td>2.16</td></tr><tr><td>CEsr-2137600</td><td>0.81</td><td>47.37</td><td>-10.07</td><td>39:08:42</td><td>0.46</td></tr><tr><td>CEsr-7531000</td><td>0.81</td><td>50.61</td><td>-3.93</td><td>42:19:23</td><td>3.64</td></tr><tr><td>CEsr-2981200</td><td>0.81</td><td>52.26</td><td>-0.79</td><td>43:33:29</td><td>4.88</td></tr><tr><td>CEsr-7420000</td><td>0.81</td><td>45.42</td><td>-13.78</td><td>42:41:08</td><td>4.00</td></tr><tr><td>CEsr-2607000</td><td>0.81</td><td>47.14</td><td>-10.50</td><td>40:34:50</td><td>1.90</td></tr><tr><td>CEsr-5019000</td><td>0.81</td><td>39.07</td><td>-25.83</td><td>38:03:05</td><td>-0.63</td></tr><tr><td>CEsr-3012200</td><td>0.81</td><td>46.74</td><td>-11.27</td><td>41:16:08</td><td>2.59</td></tr><tr><td>CEsr-5363000</td><td>0.81</td><td>34.85</td><td>-33.84</td><td>40:16:43</td><td>1.60</td></tr><tr><td>CEsr-3110000</td><td>0.81</td><td>52.31</td><td>-0.70</td><td>42:11:19</td><td>3.51</td></tr><tr><td>CEsr-3016600</td><td>0.81</td><td>43.23</td><td>-17.94</td><td>41:16:24</td><td>2.59</td></tr><tr><td>CEsr-3011300</td><td>0.81</td><td>46.12</td><td>-12.45</td><td>41:58:21</td><td>3.29</td></tr><tr><td>CEsr-5691000</td><td>0.81</td><td>55.28</td><td>4.95</td><td>41:09:39</td><td>2.48</td></tr><tr><td>CEsr-7469000</td><td>0.81</td><td>36.76</td><td>-30.21</td><td>36:45:31</td><td>-1.92</td></tr><tr><td>CEsr-2532800</td><td>0.81</td><td>59.59</td><td>13.13</td><td>42:44:53</td><td>4.07</td></tr><tr><td>CEsr-2932100</td><td>0.81</td><td>52.04</td><td>-1.21</td><td>43:07:16</td><td>4.44</td></tr><tr><td>CEsr-1983400</td><td>0.81</td><td>58.20</td><td>10.49</td><td>41:49:19</td><td>3.14</td></tr><tr><td>CEsr-4480000</td><td>0.81</td><td>46.65</td><td>-11.44</td><td>39:37:49</td><td>0.95</td></tr><tr><td>CEsr-6264000</td><td>0.81</td><td>43.60</td><td>-17.23</td><td>39:54:00</td><td>1.22</td></tr><tr><td>CEsr-2986800</td><td>0.81</td><td>40.81</td><td>-22.53</td><td>39:49:08</td><td>1.14</td></tr><tr><td>CEsr-2574400</td><td>0.81</td><td>50.93</td><td>-3.31</td><td>42:08:24</td><td>3.46</td></tr><tr><td>CEsr-4623000</td><td>0.81</td><td>50.10</td><td>-4.89</td><td>43:05:12</td><td>4.40</td></tr><tr><td>CEsr-4498000</td><td>0.81</td><td>47.21</td><td>-10.38</td><td>41:56:20</td><td>3.26</td></tr><tr><td>CEsr-1272800</td><td>0.81</td><td>52.78</td><td>0.19</td><td>40:22:14</td><td>1.69</td></tr><tr><td>CEsr-4345000</td><td>0.81</td><td>50.85</td><td>-3.47</td><td>41:22:24</td><td>2.69</td></tr><tr><td>CEsr-2135800</td><td>0.81</td><td>46.47</td><td>-11.78</td><td>42:07:45</td><td>3.45</td></tr><tr><td>CEsr-4433000</td><td>0.81</td><td>45.71</td><td>-13.23</td><td>38:30:59</td><td>-0.17</td></tr><tr><td>CEsr-4348000</td><td>0.81</td><td>47.31</td><td>-10.18</td><td>39:08:33</td><td>0.46</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CESr-4489000</td><td>0.81</td><td>54.28</td><td>3.04</td><td>44:26:12</td><td>5.75</td></tr><tr><td>CESr-4634000</td><td>0.81</td><td>47.40</td><td>-10.02</td><td>39:26:42</td><td>0.76</td></tr><tr><td>CESr-6064000</td><td>0.81</td><td>48.86</td><td>-7.24</td><td>41:29:23</td><td>2.81</td></tr><tr><td>CESr-4314000</td><td>0.81</td><td>44.88</td><td>-14.81</td><td>40:12:47</td><td>1.53</td></tr><tr><td>CESr-1424000</td><td>0.81</td><td>55.19</td><td>4.78</td><td>42:25:23</td><td>3.74</td></tr><tr><td>CESr-2119000</td><td>0.81</td><td>47.63</td><td>-9.59</td><td>40:04:38</td><td>1.40</td></tr><tr><td>CEmr-2291200</td><td>0.81</td><td>50.02</td><td>-5.03</td><td>42:11:02</td><td>3.50</td></tr><tr><td>CESr-4077000</td><td>0.81</td><td>49.16</td><td>-6.67</td><td>39:21:27</td><td>0.68</td></tr><tr><td>CESr-1634000</td><td>0.81</td><td>52.59</td><td>-0.16</td><td>39:47:57</td><td>1.12</td></tr><tr><td>CESr-6375000</td><td>0.81</td><td>53.93</td><td>2.38</td><td>42:03:11</td><td>3.37</td></tr><tr><td>CESr-2624000</td><td>0.81</td><td>50.28</td><td>-4.55</td><td>41:15:17</td><td>2.57</td></tr><tr><td>CEmr-1676900</td><td>0.81</td><td>44.73</td><td>-15.09</td><td>39:16:57</td><td>0.60</td></tr><tr><td>CESr-1551000</td><td>0.81</td><td>75.34</td><td>43.03</td><td>50:57:39</td><td>12.28</td></tr><tr><td>CEmr-1387900</td><td>0.81</td><td>54.39</td><td>3.26</td><td>42:13:18</td><td>3.54</td></tr><tr><td>CEmr-2585900</td><td>0.81</td><td>50.11</td><td>-4.88</td><td>38:57:21</td><td>0.27</td></tr><tr><td>CESr-3176000</td><td>0.81</td><td>45.17</td><td>-14.25</td><td>42:15:31</td><td>3.58</td></tr><tr><td>CESr-3663000</td><td>0.81</td><td>51.58</td><td>-2.08</td><td>40:41:25</td><td>2.01</td></tr><tr><td>CEmr-2783400</td><td>0.81</td><td>49.42</td><td>-6.17</td><td>40:25:07</td><td>1.74</td></tr><tr><td>CEmr-1683000</td><td>0.81</td><td>50.13</td><td>-4.83</td><td>42:13:41</td><td>3.55</td></tr><tr><td>CEmr-1275000</td><td>0.81</td><td>51.69</td><td>-1.87</td><td>41:30:08</td><td>2.82</td></tr><tr><td>CEmr-1332600</td><td>0.81</td><td>53.25</td><td>1.09</td><td>42:58:44</td><td>4.30</td></tr><tr><td>CESr-6289000</td><td>0.81</td><td>52.09</td><td>-1.11</td><td>41:28:29</td><td>2.79</td></tr><tr><td>CESr-2108600</td><td>0.81</td><td>48.21</td><td>-8.48</td><td>45:15:02</td><td>6.57</td></tr><tr><td>CESr-2326000</td><td>0.81</td><td>49.28</td><td>-6.44</td><td>42:56:02</td><td>4.25</td></tr><tr><td>CESr-2290300</td><td>0.81</td><td>48.75</td><td>-7.45</td><td>42:47:53</td><td>4.12</td></tr><tr><td>CEmr-1274800</td><td>0.81</td><td>53.36</td><td>1.30</td><td>41:50:21</td><td>3.16</td></tr><tr><td>CEmr-hm71700</td><td>0.81</td><td>50.44</td><td>-4.24</td><td>41:18:44</td><td>2.63</td></tr><tr><td>CESr-2574000</td><td>0.81</td><td>55.21</td><td>4.81</td><td>42:15:47</td><td>3.58</td></tr><tr><td>CESr-5486000</td><td>0.81</td><td>46.10</td><td>-12.47</td><td>39:06:22</td><td>0.42</td></tr><tr><td>CESr-6065000</td><td>0.81</td><td>38.71</td><td>-26.51</td><td>37:51:29</td><td>-0.82</td></tr><tr><td>CESr-2191000</td><td>0.81</td><td>41.05</td><td>-22.07</td><td>39:59:17</td><td>1.31</td></tr><tr><td>CESr-4401000</td><td>0.81</td><td>42.77</td><td>-18.80</td><td>38:29:12</td><td>-0.20</td></tr><tr><td>CESr-2125000</td><td>0.81</td><td>45.65</td><td>-13.33</td><td>39:12:09</td><td>0.52</td></tr><tr><td>CEmr-1272000</td><td>0.81</td><td>46.91</td><td>-10.94</td><td>39:21:48</td><td>0.68</td></tr><tr><td>CEmr-1941300</td><td>0.81</td><td>50.29</td><td>-4.53</td><td>42:25:14</td><td>3.74</td></tr><tr><td>CESr-7440000</td><td>0.81</td><td>43.02</td><td>-18.33</td><td>41:01:05</td><td>2.34</td></tr><tr><td>CESr-1683000</td><td>0.81</td><td>47.99</td><td>-8.89</td><td>39:48:47</td><td>1.13</td></tr><tr><td>CEmr-1847200</td><td>0.81</td><td>46.39</td><td>-11.94</td><td>39:46:27</td><td>1.09</td></tr><tr><td>CESr-1559000</td><td>0.81</td><td>40.61</td><td>-22.90</td><td>37:00:01</td><td>-1.68</td></tr><tr><td>CEmr-2587500</td><td>0.81</td><td>50.51</td><td>-4.11</td><td>41:08:44</td><td>2.46</td></tr><tr><td>CESr-1642000</td><td>0.81</td><td>40.24</td><td>-23.61</td><td>38:05:14</td><td>-0.59</td></tr><tr><td>CESr-7001000</td><td>0.81</td><td>62.01</td><td>17.71</td><td>40:56:34</td><td>2.26</td></tr><tr><td>CESr-1685000</td><td>0.81</td><td>52.99</td><td>0.60</td><td>40:23:52</td><td>1.72</td></tr><tr><td>CEmr-3045200</td><td>0.81</td><td>55.21</td><td>4.81</td><td>43:35:23</td><td>4.91</td></tr><tr><td>CESr-4081000</td><td>0.81</td><td>46.56</td><td>-11.61</td><td>43:32:32</td><td>4.86</td></tr><tr><td>CESr-1654000</td><td>0.81</td><td>51.13</td><td>-2.93</td><td>41:19:30</td><td>2.64</td></tr><tr><td>CESr-6358000</td><td>0.81</td><td>51.66</td><td>-1.93</td><td>42:09:45</td><td>3.48</td></tr><tr><td>CESr-1965000</td><td>0.81</td><td>46.45</td><td>-11.83</td><td>40:13:58</td><td>1.55</td></tr><tr><td>CESr-2050000</td><td>0.81</td><td>50.82</td><td>-3.52</td><td>43:28:33</td><td>4.79</td></tr><tr><td>CEmr-3015500</td><td>0.81</td><td>47.32</td><td>-10.17</td><td>38:43:58</td><td>0.05</td></tr><tr><td>CEmr-1770000</td><td>0.81</td><td>56.21</td><td>6.70</td><td>43:10:52</td><td>4.50</td></tr><tr><td>CEmr-2107500</td><td>0.81</td><td>50.93</td><td>-3.32</td><td>42:47:58</td><td>4.12</td></tr><tr><td>C06 untreated mock-infected cells</td><td>0.62595441</td><td>197.79 ± 14.68</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C06 untreated infected cells</td><td>0.63</td><td>54.03 ± 3.24</td><td>N.D</td><td>41:55:32</td><td>N.D</td></tr><tr><td>CESr-2407000</td><td>0.63</td><td>39.85</td><td>-26.25</td><td>39:06:04</td><td>-2.82</td></tr><tr><td>CEmr-2149000</td><td>0.63</td><td>48.13</td><td>-10.93</td><td>41:09:17</td><td>-0.77</td></tr><tr><td>CEmr-2362200</td><td>0.63</td><td>44.80</td><td>-17.09</td><td>38:45:04</td><td>-3.17</td></tr><tr><td>CESr-7462000</td><td>0.63</td><td>51.00</td><td>-5.62</td><td>43:07:40</td><td>1.20</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEsr-2383000</td><td>0.63</td><td>46.01</td><td>-14.85</td><td>40:19:57</td><td>-1.59</td></tr><tr><td>CEsr-2969400</td><td>0.63</td><td>50.66</td><td>-6.25</td><td>42:13:07</td><td>0.29</td></tr><tr><td>CEsr-2402000</td><td>0.63</td><td>55.34</td><td>2.43</td><td>43:09:04</td><td>1.23</td></tr><tr><td>CEsr-2638000</td><td>0.63</td><td>46.27</td><td>-14.38</td><td>39:37:00</td><td>-2.31</td></tr><tr><td>CEsr-5553000</td><td>0.63</td><td>45.45</td><td>-15.89</td><td>38:53:12</td><td>-3.04</td></tr><tr><td>CEsr-2980400</td><td>0.63</td><td>51.12</td><td>-5.40</td><td>40:41:55</td><td>-1.23</td></tr><tr><td>CEsr-3021400</td><td>0.63</td><td>43.73</td><td>-19.08</td><td>39:29:23</td><td>-2.44</td></tr><tr><td>CEsr-7360000</td><td>0.63</td><td>44.48</td><td>-17.68</td><td>40:52:59</td><td>-1.04</td></tr><tr><td>CEsr-3043000</td><td>0.63</td><td>44.75</td><td>-17.19</td><td>42:09:16</td><td>0.23</td></tr><tr><td>CEsr-4993000</td><td>0.63</td><td>42.95</td><td>-20.51</td><td>40:13:03</td><td>-1.71</td></tr><tr><td>CEsr-7373000</td><td>0.63</td><td>47.49</td><td>-12.11</td><td>40:15:00</td><td>-1.68</td></tr><tr><td>CEsr-7369000</td><td>0.63</td><td>46.64</td><td>-13.68</td><td>39:35:18</td><td>-2.34</td></tr><tr><td>CEsr-3046000</td><td>0.63</td><td>43.23</td><td>-20.00</td><td>39:37:09</td><td>-2.31</td></tr><tr><td>CEsr-3151000</td><td>0.63</td><td>40.78</td><td>-24.52</td><td>38:45:04</td><td>-3.17</td></tr><tr><td>CEsr-2956000</td><td>0.63</td><td>48.54</td><td>-10.17</td><td>39:29:16</td><td>-2.44</td></tr><tr><td>CEsr-7386000</td><td>0.63</td><td>42.47</td><td>-21.40</td><td>39:45:41</td><td>-2.16</td></tr><tr><td>CEsr-3043000</td><td>0.63</td><td>47.07</td><td>-12.88</td><td>41:58:24</td><td>0.05</td></tr><tr><td>CEsr-3046100</td><td>0.63</td><td>44.86</td><td>-16.98</td><td>41:25:39</td><td>-0.50</td></tr><tr><td>CEsr-7352000</td><td>0.63</td><td>47.93</td><td>-11.29</td><td>41:58:55</td><td>0.06</td></tr><tr><td>CEsr-2364400</td><td>0.63</td><td>46.28</td><td>-14.35</td><td>40:08:49</td><td>-1.78</td></tr><tr><td>CEsr-1122000</td><td>0.63</td><td>47.88</td><td>-11.39</td><td>40:10:04</td><td>-1.76</td></tr><tr><td>CEsr-5821000</td><td>0.63</td><td>46.55</td><td>-13.85</td><td>38:53:20</td><td>-3.04</td></tr><tr><td>CEsr-3092500</td><td>0.63</td><td>42.81</td><td>-20.77</td><td>39:27:35</td><td>-2.47</td></tr><tr><td>CEsr-6995000</td><td>0.63</td><td>46.36</td><td>-14.20</td><td>41:01:49</td><td>-0.90</td></tr><tr><td>CEsr-1167000</td><td>0.63</td><td>44.06</td><td>-18.46</td><td>41:12:41</td><td>-0.71</td></tr><tr><td>CEsr-5286000</td><td>0.63</td><td>43.39</td><td>-19.70</td><td>38:46:14</td><td>-3.15</td></tr><tr><td>CEsr-5287000</td><td>0.63</td><td>45.79</td><td>-15.26</td><td>37:13:53</td><td>-4.69</td></tr><tr><td>CEsr-1891100</td><td>0.63</td><td>43.80</td><td>-18.94</td><td>39:15:07</td><td>-2.67</td></tr><tr><td>CEsr-6827000</td><td>0.63</td><td>48.78</td><td>-9.72</td><td>41:59:03</td><td>0.06</td></tr><tr><td>CEsr-3224300</td><td>0.63</td><td>35.52</td><td>-34.26</td><td>41:08:21</td><td>-0.79</td></tr><tr><td>CEsr-3391700</td><td>0.63</td><td>47.34</td><td>-12.39</td><td>39:56:27</td><td>-1.98</td></tr><tr><td>CEsr-1870000</td><td>0.63</td><td>42.40</td><td>-21.52</td><td>39:53:35</td><td>-2.03</td></tr><tr><td>CEsr-2701200</td><td>0.63</td><td>40.70</td><td>-24.67</td><td>38:55:03</td><td>-3.01</td></tr><tr><td>CEsr-3017800</td><td>0.63</td><td>50.66</td><td>-6.24</td><td>42:48:05</td><td>0.88</td></tr><tr><td>CEsr-3221000</td><td>0.63</td><td>46.89</td><td>-13.22</td><td>41:05:30</td><td>-0.83</td></tr><tr><td>CEsr-5952000</td><td>0.63</td><td>38.12</td><td>-29.46</td><td>36:54:30</td><td>-5.02</td></tr><tr><td>CEsr-5646000</td><td>0.63</td><td>47.57</td><td>-11.97</td><td>39:57:16</td><td>-1.97</td></tr><tr><td>CEsr-7036000</td><td>0.63</td><td>45.81</td><td>-15.22</td><td>40:25:39</td><td>-1.50</td></tr><tr><td>CEsr-5021000</td><td>0.63</td><td>38.23</td><td>-29.24</td><td>38:43:46</td><td>-3.20</td></tr><tr><td>CEsr-2532500</td><td>0.63</td><td>45.70</td><td>-15.41</td><td>42:17:39</td><td>0.37</td></tr><tr><td>CEsr-5707000</td><td>0.63</td><td>36.02</td><td>-33.33</td><td>36:35:47</td><td>-5.33</td></tr><tr><td>CEsr-5777000</td><td>0.63</td><td>42.71</td><td>-20.95</td><td>41:31:44</td><td>-0.40</td></tr><tr><td>CEsr-1414100</td><td>0.63</td><td>46.19</td><td>-14.51</td><td>40:34:32</td><td>-1.35</td></tr><tr><td>CEsr-6619000</td><td>0.63</td><td>48.40</td><td>-10.43</td><td>43:05:02</td><td>1.16</td></tr><tr><td>CEsr-1750000</td><td>0.63</td><td>44.47</td><td>-17.69</td><td>40:06:08</td><td>-1.82</td></tr><tr><td>CEsr-1842900</td><td>0.63</td><td>43.50</td><td>-19.50</td><td>38:39:19</td><td>-3.27</td></tr><tr><td>CEsr-2283500</td><td>0.63</td><td>35.82</td><td>-33.71</td><td>36:58:49</td><td>-4.95</td></tr><tr><td>CEsr-7077000</td><td>0.63</td><td>39.84</td><td>-26.27</td><td>39:52:22</td><td>-2.05</td></tr><tr><td>CEsr-7052000</td><td>0.63</td><td>42.40</td><td>-21.53</td><td>40:59:57</td><td>-0.93</td></tr><tr><td>CEsr-2398200</td><td>0.63</td><td>50.59</td><td>-6.37</td><td>43:25:58</td><td>1.51</td></tr><tr><td>CEsr-7062000</td><td>0.63</td><td>46.19</td><td>-14.52</td><td>42:08:35</td><td>0.22</td></tr><tr><td>CEsr-1839000</td><td>0.63</td><td>45.73</td><td>-15.36</td><td>39:09:07</td><td>-2.77</td></tr><tr><td>CEsr-2576800</td><td>0.63</td><td>37.53</td><td>-30.54</td><td>35:56:06</td><td>-5.99</td></tr><tr><td>CEsr-3187700</td><td>0.63</td><td>43.34</td><td>-19.79</td><td>37:47:15</td><td>-4.14</td></tr><tr><td>CEsr-2138200</td><td>0.63</td><td>44.38</td><td>-17.87</td><td>41:19:39</td><td>-0.60</td></tr><tr><td>CEsr-2585500</td><td>0.63</td><td>45.29</td><td>-16.18</td><td>40:10:40</td><td>-1.75</td></tr><tr><td>CEsr-3184300</td><td>0.63</td><td>36.37</td><td>-32.69</td><td>38:28:50</td><td>-3.44</td></tr><tr><td>CEsr-3183600</td><td>0.63</td><td>39.00</td><td>-27.81</td><td>41:02:29</td><td>-0.88</td></tr><tr><td>CEsr-7108000</td><td>0.63</td><td>53.14</td><td>-1.65</td><td>40:42:33</td><td>-1.22</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEsr-7025000</td><td>0.63</td><td>41.87</td><td>-22.50</td><td>38:40:46</td><td>-3.25</td></tr><tr><td>CEmr-2107200</td><td>0.63</td><td>42.96</td><td>-20.50</td><td>39:58:44</td><td>-1.95</td></tr><tr><td>CEsr-6947000</td><td>0.63</td><td>50.45</td><td>-6.63</td><td>41:26:53</td><td>-0.48</td></tr><tr><td>CEsr-7466000</td><td>0.63</td><td>36.44</td><td>-32.56</td><td>36:41:40</td><td>-5.23</td></tr><tr><td>CEmr-1981400</td><td>0.63</td><td>47.21</td><td>-12.63</td><td>41:16:38</td><td>-0.65</td></tr><tr><td>CEsr-7010000</td><td>0.63</td><td>45.80</td><td>-15.24</td><td>41:09:23</td><td>-0.77</td></tr><tr><td>CEmr-2794900</td><td>0.63</td><td>44.48</td><td>-17.67</td><td>38:00:35</td><td>-3.92</td></tr><tr><td>CEsr-2968000</td><td>0.63</td><td>46.22</td><td>-14.47</td><td>39:56:24</td><td>-1.99</td></tr><tr><td>CEsr-7518000</td><td>0.63</td><td>42.18</td><td>-21.93</td><td>38:10:01</td><td>-3.76</td></tr><tr><td>CEmr-1617300</td><td>0.63</td><td>43.28</td><td>-19.90</td><td>39:41:21</td><td>-2.24</td></tr><tr><td>CEsr-6955000</td><td>0.63</td><td>50.13</td><td>-7.23</td><td>41:24:37</td><td>-0.52</td></tr><tr><td>CEmr-3224400</td><td>0.63</td><td>41.50</td><td>-23.19</td><td>39:22:13</td><td>-2.56</td></tr><tr><td>CEmr-1473700</td><td>0.63</td><td>44.39</td><td>-17.84</td><td>39:05:59</td><td>-2.83</td></tr><tr><td>CEsr-1999000</td><td>0.63</td><td>45.73</td><td>-15.37</td><td>38:16:14</td><td>-3.65</td></tr><tr><td>CEmr-1843100</td><td>0.63</td><td>39.85</td><td>-26.25</td><td>36:57:38</td><td>-4.96</td></tr><tr><td>CEsr-7279000</td><td>0.63</td><td>39.04</td><td>-27.75</td><td>38:56:05</td><td>-2.99</td></tr><tr><td>CEmr-1554200</td><td>0.63</td><td>50.63</td><td>-6.31</td><td>45:46:31</td><td>3.85</td></tr><tr><td>CO<sub>7</sub> untreated mock-infected cells</td><td>0.8693</td><td>186.41 ± 4.44</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>CO<sub>7</sub> untreated infected cells</td><td>0.87</td><td>54.55 ± 1.31</td><td>N.D</td><td>37:21:37</td><td>N.D</td></tr><tr><td>CEsr-6091000</td><td>0.87</td><td>54.52</td><td>-0.07</td><td>38:15:35</td><td>0.90</td></tr><tr><td>CEmr-1371700</td><td>0.87</td><td>53.27</td><td>-2.35</td><td>40:43:23</td><td>3.36</td></tr><tr><td>CEsr-6362000</td><td>0.87</td><td>71.33</td><td>30.76</td><td>49:16:16</td><td>11.91</td></tr><tr><td>CEmr-2232500</td><td>0.87</td><td>50.23</td><td>-7.93</td><td>39:06:13</td><td>1.74</td></tr><tr><td>CEsr-4565000</td><td>0.87</td><td>47.08</td><td>-13.71</td><td>38:21:00</td><td>0.99</td></tr><tr><td>CEmr-1711900</td><td>0.87</td><td>57.05</td><td>4.57</td><td>38:44:45</td><td>1.39</td></tr><tr><td>CEsr-4278000</td><td>0.87</td><td>54.73</td><td>0.32</td><td>38:17:42</td><td>0.93</td></tr><tr><td>CEsr-2077000</td><td>0.87</td><td>52.57</td><td>-3.64</td><td>36:16:23</td><td>-1.09</td></tr><tr><td>CEmr-2532400</td><td>0.87</td><td>54.48</td><td>-0.14</td><td>39:38:12</td><td>2.28</td></tr><tr><td>CEsr-4279000</td><td>0.87</td><td>54.44</td><td>-0.21</td><td>38:46:34</td><td>1.42</td></tr><tr><td>CEsr-2053000</td><td>0.87</td><td>36.07</td><td>-33.88</td><td>35:10:09</td><td>-2.19</td></tr><tr><td>CEsr-2112000</td><td>0.87</td><td>47.93</td><td>-12.15</td><td>40:15:18</td><td>2.89</td></tr><tr><td>CEsr-2054000</td><td>0.87</td><td>50.04</td><td>-8.28</td><td>37:47:24</td><td>0.43</td></tr><tr><td>CEsr-6966000</td><td>0.87</td><td>58.74</td><td>7.67</td><td>37:13:52</td><td>-0.13</td></tr><tr><td>CEsr-1673000</td><td>0.87</td><td>50.72</td><td>-7.02</td><td>37:26:44</td><td>0.09</td></tr><tr><td>CEsr-4259000</td><td>0.87</td><td>50.13</td><td>-8.11</td><td>37:13:57</td><td>-0.13</td></tr><tr><td>CEsr-5812000</td><td>0.87</td><td>46.47</td><td>-14.82</td><td>36:59:54</td><td>-0.36</td></tr><tr><td>CEmr-2501800</td><td>0.87</td><td>63.41</td><td>16.23</td><td>44:06:14</td><td>6.74</td></tr><tr><td>CEmr-2610600</td><td>0.87</td><td>52.58</td><td>-3.62</td><td>38:51:26</td><td>1.50</td></tr><tr><td>CEsr-2142000</td><td>0.87</td><td>47.41</td><td>-13.10</td><td>40:16:07</td><td>2.91</td></tr><tr><td>CEmr-1931700</td><td>0.87</td><td>51.45</td><td>-5.69</td><td>37:11:10</td><td>-0.17</td></tr><tr><td>CEsr-1674000</td><td>0.87</td><td>54.00</td><td>-1.02</td><td>39:43:22</td><td>2.36</td></tr><tr><td>CEsr-2096000</td><td>0.87</td><td>52.37</td><td>-4.00</td><td>39:06:08</td><td>1.74</td></tr><tr><td>CEsr-5182000</td><td>0.87</td><td>48.39</td><td>-11.30</td><td>38:43:59</td><td>1.37</td></tr><tr><td>CEmr-1675400</td><td>0.87</td><td>49.48</td><td>-9.31</td><td>38:14:46</td><td>0.89</td></tr><tr><td>CEmr-2986100</td><td>0.87</td><td>47.05</td><td>-13.75</td><td>40:54:54</td><td>3.55</td></tr><tr><td>CEsr-2555000</td><td>0.87</td><td>51.92</td><td>-4.83</td><td>38:20:33</td><td>0.98</td></tr><tr><td>CEsr-7290000</td><td>0.87</td><td>56.89</td><td>4.29</td><td>38:31:13</td><td>1.16</td></tr><tr><td>CEsr-7574000</td><td>0.87</td><td>50.29</td><td>-7.81</td><td>41:14:30</td><td>3.88</td></tr><tr><td>CEmr-2890700</td><td>0.87</td><td>32.02</td><td>-41.31</td><td>38:19:16</td><td>0.96</td></tr><tr><td>CEmr-2891500</td><td>0.87</td><td>63.03</td><td>15.53</td><td>41:29:24</td><td>4.13</td></tr><tr><td>CEmr-3073800</td><td>0.87</td><td>52.34</td><td>-4.06</td><td>38:46:02</td><td>1.41</td></tr><tr><td>CEmr-3080800</td><td>0.87</td><td>52.21</td><td>-4.30</td><td>38:08:51</td><td>0.79</td></tr><tr><td>CEsr-2600500</td><td>0.87</td><td>52.00</td><td>-4.68</td><td>39:10:57</td><td>1.82</td></tr><tr><td>CEmr-2329600</td><td>0.87</td><td>54.55</td><td>-0.01</td><td>42:08:46</td><td>4.79</td></tr><tr><td>CEsr-5924000</td><td>0.87</td><td>52.35</td><td>-4.03</td><td>38:24:44</td><td>1.05</td></tr><tr><td>CEsr-1605000</td><td>0.87</td><td>46.51</td><td>-14.75</td><td>35:53:29</td><td>-1.47</td></tr><tr><td>CEsr-2251000</td><td>0.87</td><td>48.58</td><td>-10.95</td><td>38:51:28</td><td>1.50</td></tr><tr><td>CEmr-3188000</td><td>0.87</td><td>50.43</td><td>-7.55</td><td>38:25:06</td><td>1.06</td></tr><tr><td>CEsr-5800000</td><td>0.87</td><td>50.65</td><td>-7.16</td><td>36:58:47</td><td>-0.38</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEmr-2875900</td><td>0.87</td><td>48.22</td><td>-11.60</td><td>36:57:09</td><td>-0.41</td></tr><tr><td>CEsr-5485000</td><td>0.87</td><td>50.98</td><td>-6.56</td><td>37:19:48</td><td>-0.03</td></tr><tr><td>CEmr-2876200</td><td>0.87</td><td>50.15</td><td>-8.08</td><td>37:32:21</td><td>0.18</td></tr><tr><td>CEpa-3</td><td>0.87</td><td>61.78</td><td>13.25</td><td>45:09:08</td><td>7.79</td></tr><tr><td>CEmr-2877100</td><td>0.87</td><td>60.59</td><td>11.07</td><td>40:37:43</td><td>3.27</td></tr><tr><td>CEsr-1591000</td><td>0.87</td><td>54.47</td><td>-0.16</td><td>38:44:08</td><td>1.38</td></tr><tr><td>CEsr-6546000</td><td>0.87</td><td>52.06</td><td>-4.57</td><td>39:15:23</td><td>1.90</td></tr><tr><td>CEsr-1612000</td><td>0.87</td><td>58.79</td><td>7.76</td><td>39:05:57</td><td>1.74</td></tr><tr><td>CEsr-1632000</td><td>0.87</td><td>59.80</td><td>9.62</td><td>38:31:56</td><td>1.17</td></tr><tr><td>CEmr-2664700</td><td>0.87</td><td>50.25</td><td>-7.88</td><td>40:39:34</td><td>3.30</td></tr><tr><td>CEmr-2876100</td><td>0.87</td><td>50.06</td><td>-8.24</td><td>39:27:44</td><td>2.10</td></tr><tr><td>CEsr-5543000</td><td>0.87</td><td>60.12</td><td>10.21</td><td>41:22:56</td><td>4.02</td></tr><tr><td>CEsr-2265000</td><td>0.87</td><td>50.52</td><td>-7.40</td><td>39:49:52</td><td>2.47</td></tr><tr><td>CEsr-5517000</td><td>0.87</td><td>56.92</td><td>4.34</td><td>38:41:51</td><td>1.34</td></tr><tr><td>CEsr-5561000</td><td>0.87</td><td>53.45</td><td>-2.02</td><td>38:48:25</td><td>1.45</td></tr><tr><td>CEsr-5571000</td><td>0.87</td><td>76.38</td><td>40.01</td><td>40:39:59</td><td>3.31</td></tr><tr><td>CEmr-2031900</td><td>0.87</td><td>53.44</td><td>-2.05</td><td>40:46:12</td><td>3.41</td></tr><tr><td>CEsr-3966000</td><td>0.87</td><td>45.73</td><td>-16.18</td><td>38:22:38</td><td>1.02</td></tr><tr><td>CEsr-5837000</td><td>0.87</td><td>45.96</td><td>-15.76</td><td>41:12:46</td><td>3.85</td></tr><tr><td>CEmr-1947400</td><td>0.87</td><td>52.94</td><td>-2.97</td><td>37:23:30</td><td>0.03</td></tr><tr><td>CEsr-4980000</td><td>0.87</td><td>56.92</td><td>4.33</td><td>38:29:32</td><td>1.13</td></tr><tr><td>CEsr-3585000</td><td>0.87</td><td>55.80</td><td>2.29</td><td>38:18:45</td><td>0.95</td></tr><tr><td>CEsr-2285000</td><td>0.87</td><td>50.78</td><td>-6.92</td><td>36:27:39</td><td>-0.90</td></tr><tr><td>CEsr-5343000</td><td>0.87</td><td>51.42</td><td>-5.74</td><td>37:35:25</td><td>0.23</td></tr><tr><td>CEsr-5347000</td><td>0.87</td><td>44.18</td><td>-19.02</td><td>37:33:05</td><td>0.19</td></tr><tr><td>CEmr-1985700</td><td>0.87</td><td>51.49</td><td>-5.61</td><td>39:56:11</td><td>2.58</td></tr><tr><td>CEmr-1278100</td><td>0.87</td><td>52.81</td><td>-3.19</td><td>39:39:20</td><td>2.30</td></tr><tr><td>CEsr-5353000</td><td>0.87</td><td>54.64</td><td>0.16</td><td>38:01:02</td><td>0.66</td></tr><tr><td>CEsr-7480000</td><td>0.87</td><td>49.45</td><td>-9.35</td><td>37:39:52</td><td>0.30</td></tr><tr><td>CEmr-1075400</td><td>0.87</td><td>55.98</td><td>2.62</td><td>37:21:53</td><td>0.00</td></tr><tr><td>CEsr-3597000</td><td>0.87</td><td>54.65</td><td>0.18</td><td>39:34:36</td><td>2.22</td></tr><tr><td>CEmr-6630000</td><td>0.87</td><td>55.88</td><td>2.42</td><td>38:03:21</td><td>0.70</td></tr><tr><td>CEsr-1827000</td><td>0.87</td><td>62.14</td><td>13.91</td><td>37:21:43</td><td>0.00</td></tr><tr><td>CEsr-4592000</td><td>0.87</td><td>50.56</td><td>-7.31</td><td>37:32:21</td><td>0.18</td></tr><tr><td>CEsr-5268000</td><td>0.87</td><td>48.90</td><td>-10.37</td><td>37:17:07</td><td>-0.08</td></tr><tr><td>CEsr-1169000</td><td>0.87</td><td>47.22</td><td>-13.45</td><td>37:05:20</td><td>-0.27</td></tr><tr><td>CEsr-7445000</td><td>0.87</td><td>56.35</td><td>3.30</td><td>38:22:40</td><td>1.02</td></tr><tr><td>CEmr-2587000</td><td>0.87</td><td>58.29</td><td>6.85</td><td>39:24:55</td><td>2.05</td></tr><tr><td>CEmr-2985600</td><td>0.87</td><td>51.16</td><td>-6.22</td><td>38:13:29</td><td>0.86</td></tr><tr><td>CEsr-2386800</td><td>0.87</td><td>54.23</td><td>-0.59</td><td>38:03:33</td><td>0.70</td></tr><tr><td>C08 untreated mock-infected cells</td><td>0.74</td><td>156.52 ± 8.90</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C08 untreated infected cells</td><td>0.74</td><td>49.02 ± 0.34</td><td>N.D</td><td>39:02:13</td><td>N.D</td></tr><tr><td>CEsr-2888000</td><td>0.74</td><td>54.76</td><td>11.70</td><td>40:43:52</td><td>1.69</td></tr><tr><td>CEsr-7038000</td><td>0.74</td><td>56.52</td><td>15.28</td><td>39:34:10</td><td>0.53</td></tr><tr><td>CEsr-2870000</td><td>0.74</td><td>49.61</td><td>1.20</td><td>39:45:25</td><td>0.72</td></tr><tr><td>CEsr-1682000</td><td>0.74</td><td>49.47</td><td>0.92</td><td>38:52:54</td><td>-0.16</td></tr><tr><td>CEsr-4845000</td><td>0.74</td><td>49.10</td><td>0.17</td><td>40:10:23</td><td>1.14</td></tr><tr><td>CEsr-4773000</td><td>0.74</td><td>49.15</td><td>0.26</td><td>39:19:26</td><td>0.29</td></tr><tr><td>CEsr-6768000</td><td>0.74</td><td>47.39</td><td>-3.34</td><td>38:26:43</td><td>-0.59</td></tr><tr><td>CEsr-1670000</td><td>0.74</td><td>54.61</td><td>11.41</td><td>39:17:33</td><td>0.26</td></tr><tr><td>CEmr-1621200</td><td>0.74</td><td>50.35</td><td>2.71</td><td>38:55:13</td><td>-0.12</td></tr><tr><td>CEsr-7191000</td><td>0.74</td><td>49.41</td><td>0.80</td><td>37:37:45</td><td>-1.41</td></tr><tr><td>CEsr-6878000</td><td>0.74</td><td>45.81</td><td>-6.54</td><td>38:17:48</td><td>-0.74</td></tr><tr><td>CEsr-6024000</td><td>0.74</td><td>47.50</td><td>-3.11</td><td>37:29:45</td><td>-1.54</td></tr><tr><td>CEsr-6523000</td><td>0.74</td><td>46.38</td><td>-5.38</td><td>37:14:06</td><td>-1.80</td></tr><tr><td>CEmr-1846000</td><td>0.74</td><td>46.81</td><td>-4.51</td><td>38:18:22</td><td>-0.73</td></tr><tr><td>CEmr-1322600</td><td>0.74</td><td>51.95</td><td>5.97</td><td>37:00:11</td><td>-2.03</td></tr><tr><td>CEsr-6861000</td><td>0.74</td><td>56.90</td><td>16.08</td><td>42:57:40</td><td>3.92</td></tr><tr><td>CEsr-6912000</td><td>0.74</td><td>47.18</td><td>-3.76</td><td>35:30:25</td><td>-3.53</td></tr><tr><td>CEsr-6931000</td><td>0.74</td><td>49.17</td><td>0.30</td><td>36:56:00</td><td>-2.10</td></tr><tr><td>CEmr-2645700</td><td>0.74</td><td>44.01</td><td>-10.23</td><td>31:57:23</td><td>-7.08</td></tr><tr><td>CEsr-1300001</td><td>0.74</td><td>51.79</td><td>5.64</td><td>39:46:38</td><td>0.74</td></tr></tbody></table>

(continued on next page)