<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CESr-6934000</td><td>0.74</td><td>50.59</td><td>3.21</td><td>40:07:31</td><td>1.09</td></tr><tr><td>CESr-6017000</td><td>0.74</td><td>51.45</td><td>4.95</td><td>40:05:38</td><td>1.06</td></tr><tr><td>CESr-1481000</td><td>0.74</td><td>50.19</td><td>2.38</td><td>38:33:23</td><td>-0.48</td></tr><tr><td>CESr-2942000</td><td>0.74</td><td>46.34</td><td>-5.48</td><td>37:29:52</td><td>-1.54</td></tr><tr><td>CESr-6928000</td><td>0.74</td><td>46.85</td><td>-4.44</td><td>36:32:46</td><td>-2.49</td></tr><tr><td>CESr-1997000</td><td>0.74</td><td>48.47</td><td>-1.14</td><td>36:39:54</td><td>-2.37</td></tr><tr><td>CESr-2704600</td><td>0.74</td><td>46.38</td><td>-5.38</td><td>38:19:59</td><td>-0.70</td></tr><tr><td>CESr-5527000</td><td>0.74</td><td>50.73</td><td>3.49</td><td>38:56:47</td><td>-0.09</td></tr><tr><td>CESr-1561400</td><td>0.74</td><td>53.15</td><td>8.43</td><td>40:09:11</td><td>1.12</td></tr><tr><td>CESr-4828000</td><td>0.74</td><td>48.29</td><td>-1.49</td><td>38:39:48</td><td>-0.37</td></tr><tr><td>CESr-2580500</td><td>0.74</td><td>47.79</td><td>-2.51</td><td>40:20:45</td><td>1.31</td></tr><tr><td>CESr-5326000</td><td>0.74</td><td>43.45</td><td>-11.36</td><td>39:46:03</td><td>0.73</td></tr><tr><td>CESr-4830000</td><td>0.74</td><td>53.29</td><td>8.70</td><td>38:34:08</td><td>-0.47</td></tr><tr><td>CESr-4836000</td><td>0.74</td><td>46.73</td><td>-4.67</td><td>38:10:11</td><td>-0.87</td></tr><tr><td>CESr-1216000</td><td>0.74</td><td>51.31</td><td>4.67</td><td>38:29:48</td><td>-0.54</td></tr><tr><td>CESr-2874400</td><td>0.74</td><td>42.17</td><td>-13.98</td><td>39:23:15</td><td>0.35</td></tr><tr><td>CESr-4838000</td><td>0.74</td><td>47.73</td><td>-2.64</td><td>36:00:08</td><td>-3.03</td></tr><tr><td>CESr-4809000</td><td>0.74</td><td>48.60</td><td>-0.86</td><td>36:57:05</td><td>-2.09</td></tr><tr><td>CESr-4833000</td><td>0.74</td><td>47.81</td><td>-2.48</td><td>38:30:05</td><td>-0.54</td></tr><tr><td>CESr-1414000</td><td>0.74</td><td>41.55</td><td>-15.25</td><td>35:08:44</td><td>-3.89</td></tr><tr><td>CESr-2637900</td><td>0.74</td><td>46.73</td><td>-4.67</td><td>38:03:05</td><td>-0.99</td></tr><tr><td>CESr-3052600</td><td>0.74</td><td>56.89</td><td>16.05</td><td>38:22:00</td><td>-0.67</td></tr><tr><td>CESr-3066000</td><td>0.74</td><td>47.64</td><td>-2.82</td><td>38:30:35</td><td>-0.53</td></tr><tr><td>CESr-2282300</td><td>0.74</td><td>52.95</td><td>8.00</td><td>35:34:22</td><td>-3.46</td></tr><tr><td>CESr-3065800</td><td>0.74</td><td>53.92</td><td>9.99</td><td>39:40:36</td><td>0.64</td></tr><tr><td>CESr-9479000</td><td>0.74</td><td>58.68</td><td>19.70</td><td>38:48:53</td><td>-0.22</td></tr><tr><td>CESr-2184000</td><td>0.74</td><td>46.53</td><td>-5.08</td><td>36:45:27</td><td>-2.28</td></tr><tr><td>CESr-1843500</td><td>0.74</td><td>47.51</td><td>-3.09</td><td>37:36:24</td><td>-1.43</td></tr><tr><td>CESr-3065200</td><td>0.74</td><td>55.76</td><td>13.75</td><td>39:51:59</td><td>0.83</td></tr><tr><td>CESr-6622000</td><td>0.74</td><td>46.23</td><td>-5.70</td><td>36:23:22</td><td>-2.65</td></tr><tr><td>CESr-2323700</td><td>0.74</td><td>45.53</td><td>-7.13</td><td>37:45:47</td><td>-1.27</td></tr><tr><td>CESr-3091000</td><td>0.74</td><td>46.05</td><td>-6.06</td><td>37:49:48</td><td>-1.21</td></tr><tr><td>CESr-3065400</td><td>0.74</td><td>56.33</td><td>14.90</td><td>40:50:06</td><td>1.80</td></tr><tr><td>CESr-4221000</td><td>0.74</td><td>45.84</td><td>-6.49</td><td>39:17:28</td><td>0.25</td></tr><tr><td>CESr-7417000</td><td>0.74</td><td>43.01</td><td>-12.27</td><td>37:18:09</td><td>-1.73</td></tr><tr><td>CESr-4260000</td><td>0.74</td><td>50.13</td><td>2.25</td><td>40:42:58</td><td>1.68</td></tr><tr><td>CESr-6121000</td><td>0.74</td><td>49.28</td><td>0.53</td><td>38:28:06</td><td>-0.57</td></tr><tr><td>CESr-2151000</td><td>0.74</td><td>40.66</td><td>-17.07</td><td>37:39:32</td><td>-1.38</td></tr><tr><td>CESr-6852000</td><td>0.74</td><td>48.03</td><td>-2.03</td><td>37:04:57</td><td>-1.95</td></tr><tr><td>CESr-4222000</td><td>0.74</td><td>47.12</td><td>-3.89</td><td>37:43:14</td><td>-1.32</td></tr><tr><td>CESr-1079000</td><td>0.74</td><td>49.09</td><td>0.13</td><td>38:06:25</td><td>-0.93</td></tr><tr><td>CESr-4251000</td><td>0.74</td><td>47.31</td><td>-3.49</td><td>45:11:38</td><td>6.16</td></tr><tr><td>CESr-2207000</td><td>0.74</td><td>44.70</td><td>-8.83</td><td>36:59:11</td><td>-2.05</td></tr><tr><td>CESr-1004000</td><td>0.74</td><td>43.69</td><td>-10.87</td><td>36:38:29</td><td>-2.40</td></tr><tr><td>CESr-3064200</td><td>0.74</td><td>54.21</td><td>10.59</td><td>38:46:37</td><td>-0.26</td></tr><tr><td>CESr-6131000</td><td>0.74</td><td>51.89</td><td>5.85</td><td>39:17:32</td><td>0.26</td></tr><tr><td>CESr-2985200</td><td>0.74</td><td>46.64</td><td>-4.86</td><td>36:34:01</td><td>-2.47</td></tr><tr><td>CESr-1458701</td><td>0.74</td><td>53.38</td><td>8.89</td><td>39:55:06</td><td>0.88</td></tr><tr><td>CESr-2986600</td><td>0.74</td><td>48.41</td><td>-1.26</td><td>39:10:09</td><td>0.13</td></tr><tr><td>CESr-2575600</td><td>0.74</td><td>51.66</td><td>5.39</td><td>38:51:23</td><td>-0.18</td></tr><tr><td>CESr-3379000</td><td>0.74</td><td>42.15</td><td>-14.01</td><td>39:13:20</td><td>0.19</td></tr><tr><td>CESr-3098500</td><td>0.74</td><td>40.18</td><td>-18.05</td><td>36:43:59</td><td>-2.30</td></tr><tr><td>CESr-6394000</td><td>0.74</td><td>49.06</td><td>0.08</td><td>38:14:34</td><td>-0.79</td></tr><tr><td>CESr-2636600</td><td>0.74</td><td>55.21</td><td>12.62</td><td>39:30:54</td><td>0.48</td></tr><tr><td>CESr-2642000</td><td>0.74</td><td>44.42</td><td>-9.39</td><td>38:24:56</td><td>-0.62</td></tr><tr><td>CESr-1550000</td><td>0.74</td><td>55.45</td><td>13.11</td><td>40:29:16</td><td>1.45</td></tr><tr><td>CESr-5667000</td><td>0.74</td><td>46.72</td><td>-4.70</td><td>36:37:56</td><td>-2.40</td></tr><tr><td>CESr-2195000</td><td>0.74</td><td>53.68</td><td>9.50</td><td>39:46:02</td><td>0.73</td></tr><tr><td>CESr-5709000</td><td>0.74</td><td>46.80</td><td>-4.53</td><td>37:12:32</td><td>-1.83</td></tr><tr><td>CESr-2286700</td><td>0.74</td><td>56.25</td><td>14.75</td><td>38:24:24</td><td>-0.63</td></tr><tr><td>C09 untreated mock-infected cells</td><td>0.836</td><td>160.87 ± 5.24</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C09 untreated infected cells</td><td>0.84</td><td>51.12 ± 0.76</td><td>N.D</td><td>39:10:05</td><td>N.D</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEmr-1502800</td><td>0.84</td><td>59.93</td><td>17.22</td><td>41:40:55</td><td>2.51</td></tr><tr><td>CEsr-4507000</td><td>0.84</td><td>56.64</td><td>10.80</td><td>39:21:05</td><td>0.18</td></tr><tr><td>CEmr-2328000</td><td>0.84</td><td>55.56</td><td>8.67</td><td>37:23:47</td><td>-1.77</td></tr><tr><td>CEsr-4402000</td><td>0.84</td><td>49.03</td><td>-4.09</td><td>38:00:16</td><td>-1.16</td></tr><tr><td>CEsr-7399000</td><td>0.84</td><td>56.01</td><td>9.56</td><td>39:04:40</td><td>-0.09</td></tr><tr><td>CEsr-4407000</td><td>0.84</td><td>59.33</td><td>16.05</td><td>39:22:24</td><td>0.21</td></tr><tr><td>CEmr-2392700</td><td>0.84</td><td>55.31</td><td>8.18</td><td>39:03:20</td><td>-0.11</td></tr><tr><td>CEmr-2392500</td><td>0.84</td><td>66.93</td><td>30.92</td><td>41:07:48</td><td>1.96</td></tr><tr><td>CEmr-1502600</td><td>0.84</td><td>59.22</td><td>15.84</td><td>41:17:27</td><td>2.12</td></tr><tr><td>CEmr-2108200</td><td>0.84</td><td>49.76</td><td>-2.67</td><td>38:02:49</td><td>-1.12</td></tr><tr><td>CEsr-2058000</td><td>0.84</td><td>53.02</td><td>3.71</td><td>39:12:39</td><td>0.04</td></tr><tr><td>CEmr-1508100</td><td>0.84</td><td>49.87</td><td>-2.45</td><td>36:39:05</td><td>-2.52</td></tr><tr><td>CEsr-4626000</td><td>0.84</td><td>52.71</td><td>3.10</td><td>40:22:30</td><td>1.21</td></tr><tr><td>CEsr-3343000</td><td>0.84</td><td>56.59</td><td>10.69</td><td>37:16:44</td><td>-1.89</td></tr><tr><td>CEmr-1503400</td><td>0.84</td><td>63.61</td><td>24.43</td><td>40:37:00</td><td>1.45</td></tr><tr><td>CEmr-2323100</td><td>0.84</td><td>54.31</td><td>6.23</td><td>36:38:05</td><td>-2.53</td></tr><tr><td>CEmr-2109800</td><td>0.84</td><td>53.82</td><td>5.28</td><td>36:53:10</td><td>-2.28</td></tr><tr><td>CEpa-5</td><td>0.84</td><td>53.18</td><td>4.01</td><td>37:38:32</td><td>-1.53</td></tr><tr><td>CEmr-3393400</td><td>0.84</td><td>55.09</td><td>7.76</td><td>39:00:23</td><td>-0.16</td></tr><tr><td>CEsr-2445000</td><td>0.84</td><td>53.94</td><td>5.51</td><td>38:41:31</td><td>-0.48</td></tr><tr><td>CEmr-1446400</td><td>0.84</td><td>50.87</td><td>-0.50</td><td>37:09:29</td><td>-2.01</td></tr><tr><td>CEsr-2492000</td><td>0.84</td><td>56.12</td><td>9.77</td><td>38:38:49</td><td>-0.52</td></tr><tr><td>CEsr-4689000</td><td>0.84</td><td>54.58</td><td>6.76</td><td>38:45:48</td><td>-0.40</td></tr><tr><td>CEsr-5048000</td><td>0.84</td><td>41.23</td><td>-19.36</td><td>38:47:49</td><td>-0.37</td></tr><tr><td>CEsr-2520000</td><td>0.84</td><td>60.04</td><td>17.44</td><td>38:45:13</td><td>-0.41</td></tr><tr><td>CEmr-1442700</td><td>0.84</td><td>53.60</td><td>4.85</td><td>37:41:21</td><td>-1.48</td></tr><tr><td>CEsr-3475000</td><td>0.84</td><td>52.15</td><td>2.01</td><td>39:52:56</td><td>0.71</td></tr><tr><td>CEmr-2037900</td><td>0.84</td><td>54.63</td><td>6.86</td><td>39:53:23</td><td>0.72</td></tr><tr><td>CEsr-3965000</td><td>0.84</td><td>50.34</td><td>-1.53</td><td>36:36:53</td><td>-2.55</td></tr><tr><td>CEsr-5078000</td><td>0.84</td><td>57.98</td><td>13.41</td><td>38:32:47</td><td>-0.62</td></tr><tr><td>CEmr-2244800</td><td>0.84</td><td>58.54</td><td>14.50</td><td>45:21:07</td><td>6.18</td></tr><tr><td>CEsr-7088000</td><td>0.84</td><td>25.14</td><td>-50.83</td><td>11:46:39</td><td>-27.39</td></tr><tr><td>CEsr-3953000</td><td>0.84</td><td>49.35</td><td>-3.47</td><td>35:05:14</td><td>-4.08</td></tr><tr><td>CEmr-1385100</td><td>0.84</td><td>53.54</td><td>4.73</td><td>40:02:05</td><td>0.87</td></tr><tr><td>CEmr-2532100</td><td>0.84</td><td>58.32</td><td>14.08</td><td>42:45:06</td><td>3.58</td></tr><tr><td>CEsr-2477000</td><td>0.84</td><td>44.34</td><td>-13.27</td><td>38:27:44</td><td>-0.71</td></tr><tr><td>CEmr-3221400</td><td>0.84</td><td>68.45</td><td>33.88</td><td>42:30:47</td><td>3.34</td></tr><tr><td>CEsr-1054000</td><td>0.84</td><td>64.55</td><td>26.26</td><td>41:40:14</td><td>2.50</td></tr><tr><td>CEsr-5509000</td><td>0.84</td><td>55.84</td><td>9.22</td><td>39:46:36</td><td>0.61</td></tr><tr><td>CEmr-3063400</td><td>0.84</td><td>56.49</td><td>10.49</td><td>39:52:06</td><td>0.70</td></tr><tr><td>CEpa-13</td><td>0.84</td><td>47.96</td><td>-6.19</td><td>36:28:24</td><td>-2.69</td></tr><tr><td>CEmr-1571000</td><td>0.84</td><td>53.90</td><td>5.43</td><td>37:38:16</td><td>-1.53</td></tr><tr><td>CEmr-2247700</td><td>0.84</td><td>43.45</td><td>-15.01</td><td>38:23:18</td><td>-0.78</td></tr><tr><td>CEsr-2006000</td><td>0.84</td><td>50.83</td><td>-0.58</td><td>39:34:52</td><td>0.41</td></tr><tr><td>CEmr-3063700</td><td>0.84</td><td>55.62</td><td>8.79</td><td>49:02:11</td><td>9.87</td></tr><tr><td>CEmr-2530300</td><td>0.84</td><td>49.60</td><td>-2.99</td><td>38:55:04</td><td>-0.25</td></tr><tr><td>CEsr-6742000</td><td>0.84</td><td>49.53</td><td>-3.12</td><td>43:46:20</td><td>4.60</td></tr><tr><td>CEsr-2470000</td><td>0.84</td><td>57.52</td><td>12.51</td><td>39:57:58</td><td>0.80</td></tr><tr><td>CEmr-3222900</td><td>0.84</td><td>50.72</td><td>-0.80</td><td>39:09:25</td><td>-0.01</td></tr><tr><td>CEmr-1848500</td><td>0.84</td><td>49.99</td><td>-2.22</td><td>38:34:29</td><td>-0.59</td></tr><tr><td>CEsr-3172000</td><td>0.84</td><td>62.66</td><td>22.56</td><td>42:58:08</td><td>3.80</td></tr><tr><td>CEmr-2241300</td><td>0.84</td><td>53.18</td><td>4.03</td><td>41:40:03</td><td>2.50</td></tr><tr><td>CEsr-3958000</td><td>0.84</td><td>53.04</td><td>3.76</td><td>39:43:58</td><td>0.56</td></tr><tr><td>CEsr-2469000</td><td>0.84</td><td>60.42</td><td>18.18</td><td>39:58:39</td><td>0.81</td></tr><tr><td>CEmr-2364800</td><td>0.84</td><td>54.59</td><td>6.78</td><td>38:10:14</td><td>-1.00</td></tr><tr><td>CEsr-4863000</td><td>0.84</td><td>59.04</td><td>15.48</td><td>38:38:55</td><td>-0.52</td></tr><tr><td>CEmr-hm63500</td><td>0.84</td><td>59.03</td><td>15.46</td><td>38:45:38</td><td>-0.41</td></tr><tr><td>CEmr-1407200</td><td>0.84</td><td>57.47</td><td>12.41</td><td>39:13:34</td><td>0.06</td></tr><tr><td>CEsr-3587000</td><td>0.84</td><td>47.45</td><td>-7.19</td><td>35:50:11</td><td>-3.33</td></tr><tr><td>CEsr-3586000</td><td>0.84</td><td>59.20</td><td>15.79</td><td>42:55:16</td><td>3.75</td></tr><tr><td>CEmr-1671400</td><td>0.84</td><td>57.46</td><td>12.39</td><td>40:52:13</td><td>1.70</td></tr><tr><td>CEmr-2396200</td><td>0.84</td><td>50.43</td><td>-1.35</td><td>38:13:29</td><td>-0.94</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z<sup>-</sup>-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEmr-2700600</td><td>0.84</td><td>54.87</td><td>7.34</td><td>39:46:24</td><td>0.61</td></tr><tr><td>CEmr-1811900</td><td>0.84</td><td>55.66</td><td>8.88</td><td>39:43:47</td><td>0.56</td></tr><tr><td>CEsr-3659000</td><td>0.84</td><td>49.73</td><td>-2.72</td><td>38:01:56</td><td>-1.14</td></tr><tr><td>CEsr-4461000</td><td>0.84</td><td>62.04</td><td>21.34</td><td>38:38:45</td><td>-0.52</td></tr><tr><td>CEmr-2811300</td><td>0.84</td><td>55.62</td><td>8.80</td><td>36:37:45</td><td>-2.54</td></tr><tr><td>CEsr-2150000</td><td>0.84</td><td>59.03</td><td>15.47</td><td>40:18:34</td><td>1.14</td></tr><tr><td>CEsr-1868000</td><td>0.84</td><td>49.51</td><td>-3.16</td><td>37:19:22</td><td>-1.85</td></tr><tr><td>CEsr-1913000</td><td>0.84</td><td>61.42</td><td>20.14</td><td>36:47:15</td><td>-2.38</td></tr><tr><td>CEmr-1676100</td><td>0.84</td><td>59.19</td><td>15.79</td><td>39:15:01</td><td>0.08</td></tr><tr><td>CEmr-1502100</td><td>0.84</td><td>64.74</td><td>26.63</td><td>38:33:28</td><td>-0.61</td></tr><tr><td>CEsr-4590000</td><td>0.84</td><td>46.52</td><td>-9.00</td><td>37:26:46</td><td>-1.72</td></tr><tr><td>CEsr-4602000</td><td>0.84</td><td>54.09</td><td>5.80</td><td>40:04:53</td><td>0.91</td></tr><tr><td>CEsr-1865000</td><td>0.84</td><td>59.23</td><td>15.85</td><td>40:36:00</td><td>1.43</td></tr><tr><td>CEsr-1874000</td><td>0.84</td><td>56.21</td><td>9.96</td><td>40:26:00</td><td>1.27</td></tr><tr><td>CEmr-2391200</td><td>0.84</td><td>51.73</td><td>1.19</td><td>39:31:27</td><td>0.36</td></tr><tr><td>CEsr-1910000</td><td>0.84</td><td>64.01</td><td>25.21</td><td>38:53:02</td><td>-0.28</td></tr><tr><td>CEsr-1920000</td><td>0.84</td><td>53.61</td><td>4.85</td><td>42:26:39</td><td>3.28</td></tr><tr><td>CEmr-2396000</td><td>0.84</td><td>57.55</td><td>12.56</td><td>39:47:18</td><td>0.62</td></tr><tr><td>C10 untreated mock-infected cells</td><td>0.82</td><td>142.83 ± 4.21</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C10 untreated infected cells</td><td>0.82</td><td>36.03 ± 2.22</td><td>N.D</td><td>34:21:36</td><td>N.D</td></tr><tr><td>CEmr-3183500</td><td>0.82</td><td>29.63</td><td>-17.77</td><td>36:35:51</td><td>1.20</td></tr><tr><td>CEsr-1385000</td><td>0.82</td><td>38.16</td><td>5.92</td><td>39:39:14</td><td>4.26</td></tr><tr><td>CEsr-1879000</td><td>0.82</td><td>36.42</td><td>1.09</td><td>39:16:29</td><td>3.88</td></tr><tr><td>CEsr-5583000</td><td>0.82</td><td>37.96</td><td>5.35</td><td>38:22:26</td><td>2.98</td></tr><tr><td>CEsr-2038000</td><td>0.82</td><td>40.27</td><td>11.78</td><td>38:51:42</td><td>3.47</td></tr><tr><td>CEmr-2881800</td><td>0.82</td><td>36.83</td><td>2.22</td><td>35:46:55</td><td>0.39</td></tr><tr><td>CEsr-2266000</td><td>0.82</td><td>35.99</td><td>-0.12</td><td>34:19:04</td><td>-1.08</td></tr><tr><td>CEsr-4083000</td><td>0.82</td><td>35.38</td><td>-1.80</td><td>34:24:14</td><td>-0.99</td></tr><tr><td>CEmr-2395800</td><td>0.82</td><td>32.54</td><td>-9.68</td><td>34:22:51</td><td>-1.02</td></tr><tr><td>CEsr-3187900</td><td>0.82</td><td>38.29</td><td>6.26</td><td>37:43:06</td><td>2.32</td></tr><tr><td>CEsr-1878000</td><td>0.82</td><td>38.60</td><td>7.13</td><td>35:36:08</td><td>0.21</td></tr><tr><td>CEmr-3188900</td><td>0.82</td><td>40.25</td><td>11.72</td><td>38:47:40</td><td>3.40</td></tr><tr><td>CEsr-4091000</td><td>0.82</td><td>37.50</td><td>4.09</td><td>34:30:57</td><td>-0.88</td></tr><tr><td>CEmr-1440100</td><td>0.82</td><td>39.95</td><td>10.88</td><td>37:07:44</td><td>1.73</td></tr><tr><td>CEsr-4106000</td><td>0.82</td><td>37.11</td><td>3.00</td><td>36:18:00</td><td>0.90</td></tr><tr><td>CEmr-2440400</td><td>0.82</td><td>34.62</td><td>-3.90</td><td>34:34:45</td><td>-0.82</td></tr><tr><td>CEmr-3370000</td><td>0.82</td><td>27.71</td><td>-23.09</td><td>34:39:18</td><td>-0.74</td></tr><tr><td>CEsr-4783000</td><td>0.82</td><td>36.99</td><td>2.67</td><td>37:10:56</td><td>1.79</td></tr><tr><td>CEmr-2574200</td><td>0.82</td><td>33.80</td><td>-6.18</td><td>36:01:56</td><td>0.64</td></tr><tr><td>CEmr-3119900</td><td>0.82</td><td>36.88</td><td>2.35</td><td>39:53:58</td><td>4.50</td></tr><tr><td>CEmr-2707900</td><td>0.82</td><td>38.46</td><td>6.74</td><td>37:27:27</td><td>2.06</td></tr><tr><td>CEmr-2612200</td><td>0.82</td><td>37.93</td><td>5.26</td><td>37:35:53</td><td>2.20</td></tr><tr><td>CEsr-1841900</td><td>0.82</td><td>37.02</td><td>2.74</td><td>35:52:19</td><td>0.48</td></tr><tr><td>CEsr-3265600</td><td>0.82</td><td>38.57</td><td>7.06</td><td>38:21:33</td><td>2.96</td></tr><tr><td>CEsr-1254000</td><td>0.82</td><td>32.27</td><td>-10.44</td><td>34:04:01</td><td>-1.33</td></tr><tr><td>CEsr-1711000</td><td>0.82</td><td>36.84</td><td>2.24</td><td>37:26:20</td><td>2.04</td></tr><tr><td>CEmr-3119000</td><td>0.82</td><td>33.88</td><td>-5.98</td><td>35:15:32</td><td>-0.14</td></tr><tr><td>CEpa-58</td><td>0.82</td><td>37.32</td><td>3.59</td><td>36:39:19</td><td>1.26</td></tr><tr><td>CEsr-6475000</td><td>0.82</td><td>32.61</td><td>-9.49</td><td>37:18:31</td><td>1.91</td></tr><tr><td>CEsr-6158000</td><td>0.82</td><td>35.29</td><td>-2.05</td><td>34:20:38</td><td>-1.05</td></tr><tr><td>CEpa-54</td><td>0.82</td><td>37.15</td><td>3.10</td><td>36:04:35</td><td>0.68</td></tr><tr><td>CEsr-6087000</td><td>0.82</td><td>37.32</td><td>3.58</td><td>36:50:52</td><td>1.45</td></tr><tr><td>CEsr-6515000</td><td>0.82</td><td>34.90</td><td>-3.13</td><td>34:59:50</td><td>-0.40</td></tr><tr><td>CEpa-45</td><td>0.82</td><td>39.19</td><td>8.78</td><td>36:00:00</td><td>0.60</td></tr><tr><td>CEsr-6298000</td><td>0.82</td><td>36.89</td><td>2.38</td><td>35:59:01</td><td>0.59</td></tr><tr><td>CEmr-2587700</td><td>0.82</td><td>39.96</td><td>10.90</td><td>36:21:13</td><td>0.96</td></tr><tr><td>CEsr-6494000</td><td>0.82</td><td>35.68</td><td>-0.97</td><td>36:01:43</td><td>0.63</td></tr><tr><td>CEsr-6255000</td><td>0.82</td><td>35.41</td><td>-1.73</td><td>34:07:02</td><td>-1.28</td></tr><tr><td>CEmr-2582900</td><td>0.82</td><td>42.90</td><td>19.05</td><td>38:37:21</td><td>3.23</td></tr><tr><td>CEsr-1843900</td><td>0.82</td><td>31.28</td><td>-13.18</td><td>33:19:09</td><td>-2.08</td></tr><tr><td>CEsr-3831000</td><td>0.82</td><td>33.61</td><td>-6.73</td><td>34:10:45</td><td>-1.22</td></tr><tr><td>CEmr-2399900</td><td>0.82</td><td>43.63</td><td>21.10</td><td>38:40:43</td><td>3.28</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEsr-4928000</td><td>0.82</td><td>35.11</td><td>-2.54</td><td>35:07:22</td><td>-0.27</td></tr><tr><td>CEmr-2381200</td><td>0.82</td><td>35.43</td><td>-1.66</td><td>33:05:09</td><td>-2.31</td></tr><tr><td>CEmr-1095900</td><td>0.82</td><td>35.75</td><td>-0.79</td><td>31:40:53</td><td>-3.72</td></tr><tr><td>CEsr-2090800</td><td>0.82</td><td>41.26</td><td>14.52</td><td>38:20:17</td><td>2.94</td></tr><tr><td>CEsr-4308000</td><td>0.82</td><td>33.50</td><td>-7.01</td><td>33:56:46</td><td>-1.45</td></tr><tr><td>CEmr-2301100</td><td>0.82</td><td>38.38</td><td>6.52</td><td>37:24:40</td><td>2.01</td></tr><tr><td>CEsr-1260000</td><td>0.82</td><td>39.14</td><td>8.63</td><td>38:06:48</td><td>2.72</td></tr><tr><td>CEmr-2385800</td><td>0.82</td><td>38.00</td><td>5.47</td><td>37:39:29</td><td>2.26</td></tr><tr><td>CEmr-2381500</td><td>0.82</td><td>40.05</td><td>11.16</td><td>38:40:07</td><td>3.27</td></tr><tr><td>CEsr-2383700</td><td>0.82</td><td>32.42</td><td>-10.01</td><td>34:46:01</td><td>-0.63</td></tr><tr><td>CEsr-4340000</td><td>0.82</td><td>37.05</td><td>2.82</td><td>34:44:53</td><td>-0.65</td></tr><tr><td>CEmr-1558200</td><td>0.82</td><td>41.12</td><td>14.12</td><td>37:14:07</td><td>1.84</td></tr><tr><td>CEsr-6129000</td><td>0.82</td><td>40.31</td><td>11.88</td><td>38:37:21</td><td>3.23</td></tr><tr><td>CEsr-7298000</td><td>0.82</td><td>37.87</td><td>5.12</td><td>35:35:33</td><td>0.20</td></tr><tr><td>CEmr-1400600</td><td>0.82</td><td>41.86</td><td>16.19</td><td>42:54:17</td><td>7.51</td></tr><tr><td>CEsr-2508000</td><td>0.82</td><td>38.70</td><td>7.40</td><td>37:26:12</td><td>2.04</td></tr><tr><td>CEmr-3180100</td><td>0.82</td><td>35.74</td><td>-0.81</td><td>42:19:09</td><td>6.92</td></tr><tr><td>CEsr-2550300</td><td>0.82</td><td>34.95</td><td>-3.00</td><td>34:58:37</td><td>-0.42</td></tr><tr><td>CEsr-7449000</td><td>0.82</td><td>42.53</td><td>18.03</td><td>40:26:59</td><td>5.05</td></tr><tr><td>CEmr-2388800</td><td>0.82</td><td>40.71</td><td>13.00</td><td>38:04:30</td><td>2.68</td></tr><tr><td>CEmr-1843800</td><td>0.82</td><td>39.40</td><td>9.35</td><td>38:28:43</td><td>3.08</td></tr><tr><td>CEsr-7446000</td><td>0.82</td><td>35.85</td><td>-0.50</td><td>36:54:35</td><td>1.51</td></tr><tr><td>CEmr-1632100</td><td>0.82</td><td>38.21</td><td>6.04</td><td>38:40:08</td><td>3.27</td></tr><tr><td>CEsr-2244700</td><td>0.82</td><td>40.69</td><td>12.94</td><td>39:17:26</td><td>3.89</td></tr><tr><td>CEsr-6047000</td><td>0.82</td><td>39.60</td><td>9.92</td><td>37:39:01</td><td>2.25</td></tr><tr><td>CEsr-2089000</td><td>0.82</td><td>37.58</td><td>4.31</td><td>38:26:39</td><td>3.05</td></tr><tr><td>CEmr-1733600</td><td>0.82</td><td>40.56</td><td>12.57</td><td>38:30:05</td><td>3.11</td></tr><tr><td>CEmr-3014200</td><td>0.82</td><td>39.01</td><td>8.27</td><td>38:02:04</td><td>2.64</td></tr><tr><td>CEsr-2587000</td><td>0.82</td><td>29.36</td><td>-18.50</td><td>29:37:51</td><td>-5.77</td></tr><tr><td>CEmr-8800000</td><td>0.82</td><td>25.27</td><td>-29.88</td><td>31:56:41</td><td>-3.45</td></tr><tr><td>CEsr-1068000</td><td>0.82</td><td>16.72</td><td>-53.61</td><td>29:28:03</td><td>-5.93</td></tr><tr><td>CEsr-4381000</td><td>0.82</td><td>38.63</td><td>7.21</td><td>39:57:47</td><td>4.57</td></tr><tr><td>CEsr-4393000</td><td>0.82</td><td>38.22</td><td>6.07</td><td>36:42:24</td><td>1.31</td></tr><tr><td>CEmr-2264900</td><td>0.82</td><td>36.27</td><td>0.65</td><td>35:41:36</td><td>0.30</td></tr><tr><td>CEmr-3096200</td><td>0.82</td><td>43.05</td><td>19.50</td><td>40:04:26</td><td>4.68</td></tr><tr><td>CEsr-4998000</td><td>0.82</td><td>39.95</td><td>10.89</td><td>36:44:23</td><td>1.34</td></tr><tr><td>CEsr-3107000</td><td>0.82</td><td>41.55</td><td>15.32</td><td>39:27:04</td><td>4.05</td></tr><tr><td>CEsr-3202200</td><td>0.82</td><td>40.76</td><td>13.14</td><td>37:22:11</td><td>1.97</td></tr><tr><td>C11 untreated mock-infected cells</td><td>0.78</td><td>154.01 ± 7.20</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C11 untreated infected cells</td><td>0.78</td><td>39.72 ± 1.17</td><td>N.D</td><td>35:14:43</td><td>N.D</td></tr><tr><td>CEsr-5668000</td><td>0.78</td><td>35.60</td><td>-10.37</td><td>34:08:38</td><td>-3.63</td></tr><tr><td>CEsr-3001000</td><td>0.78</td><td>41.95</td><td>5.63</td><td>40:38:41</td><td>2.87</td></tr><tr><td>CEsr-3124000</td><td>0.78</td><td>27.53</td><td>-30.68</td><td>32:57:47</td><td>-4.81</td></tr><tr><td>CEsr-2983000</td><td>0.78</td><td>33.71</td><td>-15.12</td><td>36:57:00</td><td>-0.83</td></tr><tr><td>CEmr-1456000</td><td>0.78</td><td>38.65</td><td>-2.69</td><td>39:57:52</td><td>2.19</td></tr><tr><td>CEsr-4596000</td><td>0.78</td><td>34.54</td><td>-13.05</td><td>35:35:16</td><td>-2.19</td></tr><tr><td>CEmr-2394000</td><td>0.78</td><td>37.71</td><td>-5.07</td><td>38:36:20</td><td>0.83</td></tr><tr><td>CEsr-4103000</td><td>0.78</td><td>43.00</td><td>8.25</td><td>38:19:34</td><td>0.55</td></tr><tr><td>CEsr-3022000</td><td>0.78</td><td>37.14</td><td>-6.50</td><td>34:15:44</td><td>-3.51</td></tr><tr><td>CEsr-4652000</td><td>0.78</td><td>40.25</td><td>1.34</td><td>38:56:32</td><td>1.17</td></tr><tr><td>CEsr-3805000</td><td>0.78</td><td>37.84</td><td>-4.73</td><td>36:24:19</td><td>-1.37</td></tr><tr><td>CEsr-7041000</td><td>0.78</td><td>42.14</td><td>6.09</td><td>39:31:45</td><td>1.75</td></tr><tr><td>CEsr-2762000</td><td>0.78</td><td>40.93</td><td>3.04</td><td>37:51:17</td><td>0.08</td></tr><tr><td>CEsr-5204000</td><td>0.78</td><td>35.78</td><td>-9.91</td><td>36:28:06</td><td>-1.31</td></tr><tr><td>CEsr-3806000</td><td>0.78</td><td>35.14</td><td>-11.54</td><td>34:50:48</td><td>-2.93</td></tr><tr><td>CEsr-3853000</td><td>0.78</td><td>38.21</td><td>-3.79</td><td>36:16:50</td><td>-1.49</td></tr><tr><td>CEmr-1678600</td><td>0.78</td><td>40.20</td><td>1.20</td><td>36:53:51</td><td>-0.88</td></tr><tr><td>CEsr-7028000</td><td>0.78</td><td>40.63</td><td>2.28</td><td>37:33:29</td><td>-0.22</td></tr><tr><td>CEsr-5163000</td><td>0.78</td><td>30.19</td><td>-24.00</td><td>32:28:09</td><td>-5.31</td></tr><tr><td>CEsr-5130000</td><td>0.78</td><td>27.78</td><td>-30.06</td><td>31:50:42</td><td>-5.93</td></tr></tbody></table>

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<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEmr-2969300</td><td>0.78</td><td>39.44</td><td>-0.71</td><td>35:42:51</td><td>-2.06</td></tr><tr><td>CEsr-3896000</td><td>0.78</td><td>33.02</td><td>-16.86</td><td>37:27:16</td><td>-0.32</td></tr><tr><td>CEmr-2966300</td><td>0.78</td><td>37.77</td><td>-4.91</td><td>39:27:47</td><td>1.69</td></tr><tr><td>CEsr-1549000</td><td>0.78</td><td>35.37</td><td>-10.94</td><td>34:35:41</td><td>-3.18</td></tr><tr><td>CEsr-1456000</td><td>0.78</td><td>37.20</td><td>-6.35</td><td>36:16:59</td><td>-1.49</td></tr><tr><td>CEmr-2631900</td><td>0.78</td><td>35.26</td><td>-11.23</td><td>33:41:13</td><td>-4.09</td></tr><tr><td>CEsr-2798000</td><td>0.78</td><td>38.46</td><td>-3.18</td><td>33:42:23</td><td>-4.07</td></tr><tr><td>CEmr-3046200</td><td>0.78</td><td>38.91</td><td>-2.05</td><td>37:14:35</td><td>-0.52</td></tr><tr><td>CEsr-2804000</td><td>0.78</td><td>41.74</td><td>5.09</td><td>35:41:35</td><td>-2.08</td></tr><tr><td>CEsr-2709000</td><td>0.78</td><td>36.88</td><td>-7.15</td><td>36:02:22</td><td>-1.74</td></tr><tr><td>CEsr-3702000</td><td>0.78</td><td>36.60</td><td>-7.86</td><td>39:33:34</td><td>1.78</td></tr><tr><td>CEsr-1315000</td><td>0.78</td><td>33.69</td><td>-15.19</td><td>36:22:08</td><td>-1.41</td></tr><tr><td>CEsr-2875000</td><td>0.78</td><td>43.14</td><td>8.60</td><td>39:43:25</td><td>1.95</td></tr><tr><td>CEmr-2991300</td><td>0.78</td><td>39.94</td><td>0.56</td><td>35:49:40</td><td>-1.95</td></tr><tr><td>CEsr-2247200</td><td>0.78</td><td>30.14</td><td>-24.12</td><td>2:12:52</td><td>-35.56</td></tr><tr><td>CEsr-2779000</td><td>0.78</td><td>33.23</td><td>-16.35</td><td>34:33:20</td><td>-3.22</td></tr><tr><td>CEmr-3040000</td><td>0.78</td><td>36.38</td><td>-8.42</td><td>34:05:51</td><td>-3.68</td></tr><tr><td>CEsr-2868000</td><td>0.78</td><td>35.54</td><td>-10.52</td><td>35:53:18</td><td>-1.89</td></tr><tr><td>CEsr-1262000</td><td>0.78</td><td>39.38</td><td>-0.86</td><td>37:35:11</td><td>-0.19</td></tr><tr><td>CEmr-2989700</td><td>0.78</td><td>56.43</td><td>42.07</td><td>52:52:23</td><td>15.10</td></tr><tr><td>CEmr-3055700</td><td>0.78</td><td>47.85</td><td>20.47</td><td>51:38:39</td><td>13.87</td></tr><tr><td>CEsr-3346000</td><td>0.78</td><td>33.95</td><td>-14.53</td><td>32:48:25</td><td>-4.97</td></tr><tr><td>CEsr-1289000</td><td>0.78</td><td>38.35</td><td>-3.45</td><td>35:31:47</td><td>-2.25</td></tr><tr><td>CEmr-3059900</td><td>0.78</td><td>33.54</td><td>-15.55</td><td>34:30:33</td><td>-3.27</td></tr><tr><td>CEmr-1982700</td><td>0.78</td><td>39.32</td><td>-1.00</td><td>36:18:50</td><td>-1.46</td></tr><tr><td>CEsr-1405000</td><td>0.78</td><td>39.34</td><td>-0.96</td><td>37:08:34</td><td>-0.63</td></tr><tr><td>CEsr-1292000</td><td>0.78</td><td>34.61</td><td>-12.86</td><td>34:11:21</td><td>-3.59</td></tr><tr><td>CEpa-21</td><td>0.78</td><td>43.98</td><td>10.73</td><td>38:01:47</td><td>0.25</td></tr><tr><td>CEsr-2417000</td><td>0.78</td><td>37.33</td><td>-6.01</td><td>35:34:16</td><td>-2.20</td></tr><tr><td>CEmr-2361400</td><td>0.78</td><td>41.91</td><td>5.51</td><td>42:39:39</td><td>4.89</td></tr><tr><td>CEsr-7473000</td><td>0.78</td><td>31.11</td><td>-21.69</td><td>34:22:40</td><td>-3.40</td></tr><tr><td>CEmr-3018300</td><td>0.78</td><td>34.41</td><td>-13.36</td><td>34:51:26</td><td>-2.92</td></tr><tr><td>CEsr-2266400</td><td>0.78</td><td>37.48</td><td>-5.63</td><td>36:06:16</td><td>-1.67</td></tr><tr><td>CEsr-1825000</td><td>0.78</td><td>42.51</td><td>7.03</td><td>35:17:55</td><td>-2.48</td></tr><tr><td>CEmr-3012400</td><td>0.78</td><td>37.03</td><td>-6.78</td><td>37:24:49</td><td>-0.36</td></tr><tr><td>CEsr-6626000</td><td>0.78</td><td>33.47</td><td>-15.74</td><td>32:21:50</td><td>-5.41</td></tr><tr><td>CEpa-24</td><td>0.78</td><td>44.59</td><td>12.25</td><td>41:08:05</td><td>3.36</td></tr><tr><td>CEmr-3094000</td><td>0.78</td><td>31.64</td><td>-20.34</td><td>32:52:52</td><td>-4.89</td></tr><tr><td>CEmr-2660600</td><td>0.78</td><td>33.23</td><td>-16.35</td><td>33:45:06</td><td>-4.02</td></tr><tr><td>CEmr-3046600</td><td>0.78</td><td>37.75</td><td>-4.95</td><td>39:05:52</td><td>1.32</td></tr><tr><td>CEmr-3015100</td><td>0.78</td><td>36.61</td><td>-7.84</td><td>32:58:43</td><td>-4.80</td></tr><tr><td>CEsr-7065000</td><td>0.78</td><td>21.78</td><td>-45.17</td><td>11:58:06</td><td>-25.81</td></tr><tr><td>CEmr-3094600</td><td>0.78</td><td>40.89</td><td>2.95</td><td>39:41:51</td><td>1.92</td></tr><tr><td>CEsr-6949000</td><td>0.78</td><td>42.58</td><td>7.20</td><td>35:12:39</td><td>-2.56</td></tr><tr><td>CEmr-3013300</td><td>0.78</td><td>38.53</td><td>-2.99</td><td>35:40:17</td><td>-2.10</td></tr><tr><td>CEmr-2758000</td><td>0.78</td><td>44.53</td><td>12.10</td><td>39:20:27</td><td>1.57</td></tr><tr><td>CEsr-2224000</td><td>0.78</td><td>41.36</td><td>4.12</td><td>37:21:03</td><td>-0.42</td></tr><tr><td>CEmr-1501300</td><td>0.78</td><td>39.26</td><td>-1.15</td><td>36:55:34</td><td>-0.85</td></tr><tr><td>CEsr-2424000</td><td>0.78</td><td>41.56</td><td>4.64</td><td>36:55:32</td><td>-0.85</td></tr><tr><td>CEsr-2389000</td><td>0.78</td><td>35.95</td><td>-9.50</td><td>36:58:33</td><td>-0.80</td></tr><tr><td>CEsr-2635000</td><td>0.78</td><td>38.40</td><td>-3.32</td><td>39:59:15</td><td>2.21</td></tr><tr><td>CEsr-2426000</td><td>0.78</td><td>39.91</td><td>0.49</td><td>37:31:10</td><td>-0.26</td></tr><tr><td>CEsr-2420000</td><td>0.78</td><td>39.98</td><td>0.64</td><td>34:02:57</td><td>-3.73</td></tr><tr><td>CEsr-2401000</td><td>0.78</td><td>37.11</td><td>-6.58</td><td>35:40:57</td><td>-2.09</td></tr><tr><td>CEsr-5109000</td><td>0.78</td><td>38.62</td><td>-2.78</td><td>34:58:30</td><td>-2.80</td></tr><tr><td>CEsr-2380000</td><td>0.78</td><td>37.13</td><td>-6.52</td><td>33:23:08</td><td>-4.39</td></tr><tr><td>CEmr-2326200</td><td>0.78</td><td>37.70</td><td>-5.08</td><td>34:12:36</td><td>-3.57</td></tr><tr><td>CEsr-5176000</td><td>0.78</td><td>31.41</td><td>-20.91</td><td>34:27:48</td><td>-3.31</td></tr><tr><td>CEsr-1259000</td><td>0.78</td><td>41.08</td><td>3.43</td><td>39:01:33</td><td>1.25</td></tr><tr><td>CEmr-2889900</td><td>0.78</td><td>41.62</td><td>4.77</td><td>37:09:55</td><td>-0.61</td></tr><tr><td>C12 untreated mock-infected cells</td><td>0.82</td><td>134.02 ± 2.13</td><td>N.D</td><td>N.D</td><td>N.D</td></tr></tbody></table>

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<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z<sup>-</sup>-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>C12 untreated infected cells</td><td>0.82</td><td>39.26 ± 3.41</td><td>N.D</td><td>34:11:46</td><td>N.D</td></tr><tr><td>CESr-5345000</td><td>0.82</td><td>41.14</td><td>4.80</td><td>38:19:04</td><td>-0.56</td></tr><tr><td>CEmr-3093500</td><td>0.82</td><td>34.32</td><td>-12.58</td><td>36:11:36</td><td>-2.69</td></tr><tr><td>CEmr-2049200</td><td>0.82</td><td>38.17</td><td>-2.78</td><td>39:36:44</td><td>0.73</td></tr><tr><td>CESr-4970000</td><td>0.82</td><td>36.58</td><td>-6.82</td><td>36:22:09</td><td>-2.51</td></tr><tr><td>CEsr-3582000</td><td>0.82</td><td>40.54</td><td>3.26</td><td>37:30:27</td><td>-1.37</td></tr><tr><td>CEsr-6540000</td><td>0.82</td><td>40.33</td><td>2.73</td><td>38:29:21</td><td>-0.39</td></tr><tr><td>CEsr-3957000</td><td>0.82</td><td>37.96</td><td>-3.32</td><td>37:10:21</td><td>-1.71</td></tr><tr><td>CEsr-4615000</td><td>0.82</td><td>42.16</td><td>7.38</td><td>39:59:38</td><td>1.11</td></tr><tr><td>CEmr-1943400</td><td>0.82</td><td>39.65</td><td>0.99</td><td>34:42:08</td><td>-4.18</td></tr><tr><td>CEsr-5765000</td><td>0.82</td><td>45.63</td><td>16.21</td><td>39:17:31</td><td>0.41</td></tr><tr><td>CEsr-4022000</td><td>0.82</td><td>38.16</td><td>-2.81</td><td>37:12:22</td><td>-1.67</td></tr><tr><td>CEsr-3584000</td><td>0.82</td><td>39.75</td><td>1.26</td><td>34:59:22</td><td>-3.89</td></tr><tr><td>CEsr-1907000</td><td>0.82</td><td>45.97</td><td>17.08</td><td>38:33:21</td><td>-0.33</td></tr><tr><td>CEsr-3768000</td><td>0.82</td><td>43.35</td><td>10.42</td><td>38:50:25</td><td>-0.04</td></tr><tr><td>CEmr-1631300</td><td>0.82</td><td>38.64</td><td>-1.57</td><td>36:54:48</td><td>-1.97</td></tr><tr><td>CEmr-1831800</td><td>0.82</td><td>40.36</td><td>2.80</td><td>38:34:24</td><td>-0.31</td></tr><tr><td>CEsr-2960000</td><td>0.82</td><td>41.42</td><td>5.50</td><td>47:25:59</td><td>8.55</td></tr><tr><td>CEsr-3548000</td><td>0.82</td><td>33.54</td><td>-14.57</td><td>34:09:26</td><td>-4.72</td></tr><tr><td>CEmr-1271000</td><td>0.82</td><td>39.39</td><td>0.33</td><td>36:28:03</td><td>-2.41</td></tr><tr><td>CEsr-7345000</td><td>0.82</td><td>37.70</td><td>-3.98</td><td>38:13:36</td><td>-0.65</td></tr><tr><td>CEsr-2959000</td><td>0.82</td><td>40.81</td><td>3.95</td><td>41:33:16</td><td>2.67</td></tr><tr><td>CEsr-7293000</td><td>0.82</td><td>36.89</td><td>-6.05</td><td>37:36:30</td><td>-1.27</td></tr><tr><td>CEsr-2901000</td><td>0.82</td><td>39.02</td><td>-0.62</td><td>35:18:22</td><td>-3.57</td></tr><tr><td>CEsr-7348000</td><td>0.82</td><td>35.89</td><td>-8.57</td><td>35:38:07</td><td>-3.25</td></tr><tr><td>CEsr-2936000</td><td>0.82</td><td>37.26</td><td>-5.08</td><td>35:10:17</td><td>-3.71</td></tr><tr><td>CEsr-3549000</td><td>0.82</td><td>37.30</td><td>-4.99</td><td>37:59:20</td><td>-0.89</td></tr><tr><td>CEsr-2248000</td><td>0.82</td><td>36.62</td><td>-6.73</td><td>33:52:10</td><td>-5.01</td></tr><tr><td>CEsr-5820000</td><td>0.82</td><td>43.30</td><td>10.29</td><td>42:10:23</td><td>3.29</td></tr><tr><td>CEsr-2974000</td><td>0.82</td><td>38.33</td><td>-2.36</td><td>34:00:54</td><td>-4.87</td></tr><tr><td>CEmr-2023800</td><td>0.82</td><td>34.83</td><td>-11.29</td><td>37:10:23</td><td>-1.71</td></tr><tr><td>CEsr-2479000</td><td>0.82</td><td>38.18</td><td>-2.75</td><td>36:04:43</td><td>-2.80</td></tr><tr><td>CEsr-7461000</td><td>0.82</td><td>39.91</td><td>1.67</td><td>37:52:28</td><td>-1.01</td></tr><tr><td>CEsr-6077000</td><td>0.82</td><td>41.92</td><td>6.78</td><td>38:12:21</td><td>-0.68</td></tr><tr><td>CEsr-5856000</td><td>0.82</td><td>38.09</td><td>-2.98</td><td>34:31:33</td><td>-4.36</td></tr><tr><td>CEsr-2488000</td><td>0.82</td><td>33.21</td><td>-15.42</td><td>33:49:20</td><td>-5.06</td></tr><tr><td>CEmr-2028200</td><td>0.82</td><td>37.96</td><td>-3.30</td><td>35:00:15</td><td>-3.88</td></tr><tr><td>CEsr-6162000</td><td>0.82</td><td>50.25</td><td>28.01</td><td>41:24:16</td><td>2.52</td></tr><tr><td>CEsr-2501000</td><td>0.82</td><td>36.98</td><td>-5.82</td><td>36:31:39</td><td>-2.35</td></tr><tr><td>CEsr-2159000</td><td>0.82</td><td>41.57</td><td>5.88</td><td>35:16:56</td><td>-3.60</td></tr><tr><td>CEsr-1940000</td><td>0.82</td><td>35.21</td><td>-10.31</td><td>37:25:57</td><td>-1.45</td></tr><tr><td>CEsr-5861000</td><td>0.82</td><td>39.63</td><td>0.94</td><td>39:01:26</td><td>0.14</td></tr><tr><td>CEsr-2490000</td><td>0.82</td><td>37.41</td><td>-4.72</td><td>33:39:29</td><td>-5.22</td></tr><tr><td>CEsr-7419000</td><td>0.82</td><td>36.41</td><td>-7.26</td><td>37:01:46</td><td>-1.85</td></tr><tr><td>CEsr-5862000</td><td>0.82</td><td>38.23</td><td>-2.62</td><td>36:23:42</td><td>-2.49</td></tr><tr><td>CEmr-2559000</td><td>0.82</td><td>32.89</td><td>-16.22</td><td>32:57:50</td><td>-5.92</td></tr><tr><td>CEsr-6658000</td><td>0.82</td><td>36.34</td><td>-7.45</td><td>36:40:07</td><td>-2.21</td></tr><tr><td>CEsr-5580000</td><td>0.82</td><td>36.51</td><td>-7.02</td><td>35:17:20</td><td>-3.59</td></tr><tr><td>CEsr-4981000</td><td>0.82</td><td>45.68</td><td>16.35</td><td>42:04:53</td><td>3.20</td></tr><tr><td>CEsr-2735000</td><td>0.82</td><td>44.16</td><td>12.48</td><td>39:44:27</td><td>0.86</td></tr><tr><td>CEsr-5817000</td><td>0.82</td><td>41.09</td><td>4.65</td><td>35:47:12</td><td>-3.09</td></tr><tr><td>CEsr-3235</td><td>0.82</td><td>35.64</td><td>-9.21</td><td>36:58:49</td><td>-1.90</td></tr><tr><td>CEsr-3265000</td><td>0.82</td><td>38.83</td><td>-1.08</td><td>35:14:37</td><td>-3.64</td></tr><tr><td>CEmr-1415000</td><td>0.82</td><td>42.29</td><td>7.71</td><td>36:01:14</td><td>-2.86</td></tr><tr><td>CEsr-1361000</td><td>0.82</td><td>39.88</td><td>1.57</td><td>36:14:29</td><td>-2.64</td></tr><tr><td>CEsr-2724000</td><td>0.82</td><td>38.55</td><td>-1.82</td><td>35:12:32</td><td>-3.67</td></tr><tr><td>CEsr-2579000</td><td>0.82</td><td>29.82</td><td>-24.05</td><td>37:47:15</td><td>-1.09</td></tr><tr><td>CEsr-2546000</td><td>0.82</td><td>40.60</td><td>3.41</td><td>37:05:01</td><td>-1.80</td></tr><tr><td>CEsr-3257000</td><td>0.82</td><td>38.30</td><td>-2.44</td><td>36:19:40</td><td>-2.55</td></tr><tr><td>CEsr-6195000</td><td>0.82</td><td>36.70</td><td>-6.51</td><td>40:22:23</td><td>1.49</td></tr><tr><td>CEsr-7101000</td><td>0.82</td><td>40.78</td><td>3.88</td><td>34:48:23</td><td>-4.07</td></tr><tr><td>CEsr-3736000</td><td>0.82</td><td>41.06</td><td>4.59</td><td>35:59:33</td><td>-2.89</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CESr-3248000</td><td>0.82</td><td>42.54</td><td>8.36</td><td>36:58:37</td><td>-1.90</td></tr><tr><td>CESr-3259000</td><td>0.82</td><td>38.88</td><td>-0.96</td><td>36:00:26</td><td>-2.87</td></tr><tr><td>CESr-1398000</td><td>0.82</td><td>37.46</td><td>-4.58</td><td>40:02:41</td><td>1.16</td></tr><tr><td>CESr-3438000</td><td>0.82</td><td>39.86</td><td>1.52</td><td>37:52:54</td><td>-1.00</td></tr><tr><td>CESr-3119000</td><td>0.82</td><td>38.31</td><td>-2.41</td><td>36:27:10</td><td>-2.43</td></tr><tr><td>CEmr-2702400</td><td>0.82</td><td>40.48</td><td>3.12</td><td>36:44:26</td><td>-2.14</td></tr><tr><td>CEmr-3170200</td><td>0.82</td><td>48.56</td><td>23.70</td><td>44:00:24</td><td>5.13</td></tr><tr><td>CESr-5727000</td><td>0.82</td><td>37.44</td><td>-4.65</td><td>37:20:14</td><td>-1.54</td></tr><tr><td>CESr-2790000</td><td>0.82</td><td>38.74</td><td>-1.33</td><td>36:22:49</td><td>-2.50</td></tr><tr><td>CESr-2834000</td><td>0.82</td><td>37.83</td><td>-3.64</td><td>35:57:42</td><td>-2.92</td></tr><tr><td>CESr-2739000</td><td>0.82</td><td>37.37</td><td>-4.82</td><td>37:30:37</td><td>-1.37</td></tr><tr><td>CESr-2792000</td><td>0.82</td><td>40.01</td><td>1.90</td><td>38:28:30</td><td>-0.41</td></tr><tr><td>CESr-2770000</td><td>0.82</td><td>41.50</td><td>5.70</td><td>36:59:50</td><td>-1.88</td></tr><tr><td>CESr-2757000</td><td>0.82</td><td>42.16</td><td>7.37</td><td>39:04:10</td><td>0.19</td></tr><tr><td>CESr-2856000</td><td>0.82</td><td>42.93</td><td>9.35</td><td>38:46:09</td><td>-0.11</td></tr><tr><td>CESr-7096000</td><td>0.82</td><td>47.08</td><td>19.91</td><td>40:53:27</td><td>2.01</td></tr><tr><td>CESr-2784000</td><td>0.82</td><td>39.64</td><td>0.97</td><td>35:34:49</td><td>-3.30</td></tr><tr><td>CESr-5760000</td><td>0.82</td><td>41.76</td><td>6.36</td><td>36:49:44</td><td>-2.05</td></tr><tr><td>CESr-2752000</td><td>0.82</td><td>45.04</td><td>14.71</td><td>41:16:10</td><td>2.39</td></tr><tr><td>C13 untreated mock-infected cells</td><td>0.64</td><td>128.15 ± 9.55</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C13 untreated infected cells</td><td>0.64</td><td>36.71 ± 1.48</td><td>N.D</td><td>35:00:51</td><td>N.D</td></tr><tr><td>CEmr-2240100</td><td>0.64</td><td>46.00</td><td>25.32</td><td>39:20:56</td><td>2.54</td></tr><tr><td>CEmr-7100000</td><td>0.64</td><td>44.05</td><td>20.00</td><td>38:53:23</td><td>2.08</td></tr><tr><td>CEmr-1811300</td><td>0.64</td><td>42.12</td><td>14.73</td><td>38:28:19</td><td>1.66</td></tr><tr><td>CESr-4872000</td><td>0.64</td><td>41.41</td><td>12.81</td><td>36:29:54</td><td>-0.31</td></tr><tr><td>CESr-1968000</td><td>0.64</td><td>40.91</td><td>11.45</td><td>39:21:44</td><td>2.55</td></tr><tr><td>CEmr-1998800</td><td>0.64</td><td>52.00</td><td>41.65</td><td>43:09:47</td><td>6.35</td></tr><tr><td>CESr-4202000</td><td>0.64</td><td>44.27</td><td>20.60</td><td>37:43:45</td><td>0.92</td></tr><tr><td>CEmr-3010400</td><td>0.64</td><td>41.70</td><td>13.60</td><td>37:42:13</td><td>0.89</td></tr><tr><td>CESr-7564000</td><td>0.64</td><td>41.04</td><td>11.81</td><td>35:01:43</td><td>-1.78</td></tr><tr><td>CEmr-1942700</td><td>0.64</td><td>42.44</td><td>15.62</td><td>37:46:55</td><td>0.97</td></tr><tr><td>CESr-1816000</td><td>0.64</td><td>44.70</td><td>21.77</td><td>38:44:38</td><td>1.93</td></tr><tr><td>CESr-4886000</td><td>0.64</td><td>41.52</td><td>13.12</td><td>40:52:54</td><td>4.07</td></tr><tr><td>CEmr-2142200</td><td>0.64</td><td>36.05</td><td>-1.79</td><td>40:19:57</td><td>3.52</td></tr><tr><td>CESr-6866000</td><td>0.64</td><td>37.10</td><td>1.07</td><td>35:13:06</td><td>-1.59</td></tr><tr><td>CEmr-3010600</td><td>0.64</td><td>39.23</td><td>6.87</td><td>36:22:34</td><td>-0.43</td></tr><tr><td>CESr-2093000</td><td>0.64</td><td>42.73</td><td>16.40</td><td>37:10:53</td><td>0.37</td></tr><tr><td>CEmr-3046300</td><td>0.64</td><td>39.93</td><td>8.79</td><td>39:15:42</td><td>2.45</td></tr><tr><td>CESr-7104000</td><td>0.64</td><td>16.97</td><td>-53.78</td><td>0:54:48</td><td>-35.90</td></tr><tr><td>CESr-3285000</td><td>0.64</td><td>36.15</td><td>-1.53</td><td>34:27:54</td><td>-2.34</td></tr><tr><td>CESr-3828000</td><td>0.64</td><td>36.18</td><td>-1.43</td><td>34:27:40</td><td>-2.35</td></tr><tr><td>CESr-7094000</td><td>0.64</td><td>28.28</td><td>-22.97</td><td>34:30:11</td><td>-2.31</td></tr><tr><td>CESr-4130000</td><td>0.64</td><td>30.88</td><td>-15.88</td><td>33:28:25</td><td>-3.34</td></tr><tr><td>CESr-3837000</td><td>0.64</td><td>40.84</td><td>11.26</td><td>36:09:50</td><td>-0.65</td></tr><tr><td>CESr-2829000</td><td>0.64</td><td>42.94</td><td>16.97</td><td>40:42:06</td><td>3.89</td></tr><tr><td>CESr-3927000</td><td>0.64</td><td>43.72</td><td>19.11</td><td>38:07:59</td><td>1.32</td></tr><tr><td>CESr-5740000</td><td>0.64</td><td>40.74</td><td>10.98</td><td>35:43:59</td><td>-1.08</td></tr><tr><td>CEmr-2621100</td><td>0.64</td><td>29.18</td><td>-20.50</td><td>31:04:20</td><td>-5.74</td></tr><tr><td>CESr-4173000</td><td>0.64</td><td>41.45</td><td>12.91</td><td>36:02:00</td><td>-0.78</td></tr><tr><td>CESr-4126000</td><td>0.64</td><td>43.07</td><td>17.33</td><td>34:30:28</td><td>-2.30</td></tr><tr><td>CESr-3657000</td><td>0.64</td><td>36.40</td><td>-0.83</td><td>34:33:13</td><td>-2.26</td></tr><tr><td>CEmr-3188600</td><td>0.64</td><td>42.48</td><td>15.73</td><td>33:38:48</td><td>-3.16</td></tr><tr><td>CESr-4129000</td><td>0.64</td><td>23.43</td><td>-36.17</td><td>30:58:19</td><td>-5.84</td></tr><tr><td>CEmr-2106500</td><td>0.64</td><td>38.85</td><td>5.84</td><td>39:14:52</td><td>2.44</td></tr><tr><td>CESr-2988100</td><td>0.64</td><td>31.40</td><td>-14.45</td><td>33:23:33</td><td>-3.42</td></tr><tr><td>CESr-4086000</td><td>0.64</td><td>42.46</td><td>15.67</td><td>34:38:18</td><td>-2.17</td></tr><tr><td>CESr-1576000</td><td>0.64</td><td>39.84</td><td>8.53</td><td>34:56:00</td><td>-1.88</td></tr><tr><td>CESr-4559000</td><td>0.64</td><td>36.86</td><td>0.42</td><td>34:10:55</td><td>-2.63</td></tr><tr><td>CEmr-1505700</td><td>0.64</td><td>39.29</td><td>7.04</td><td>35:57:38</td><td>-0.85</td></tr><tr><td>CESr-4553000</td><td>0.64</td><td>38.24</td><td>4.18</td><td>33:54:23</td><td>-2.90</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEsr-4568000</td><td>0.64</td><td>36.85</td><td>0.39</td><td>36:35:09</td><td>-0.22</td></tr><tr><td>CEsr-2107400</td><td>0.64</td><td>41.53</td><td>13.15</td><td>35:46:15</td><td>-1.04</td></tr><tr><td>CEsr-4544000</td><td>0.64</td><td>43.94</td><td>19.71</td><td>37:44:58</td><td>0.94</td></tr><tr><td>CEsr-2663600</td><td>0.64</td><td>41.89</td><td>14.11</td><td>35:41:46</td><td>-1.11</td></tr><tr><td>CEsr-2569000</td><td>0.64</td><td>38.34</td><td>4.45</td><td>33:31:56</td><td>-3.28</td></tr><tr><td>CEsr-2286800</td><td>0.64</td><td>36.70</td><td>-0.02</td><td>33:05:32</td><td>-3.72</td></tr><tr><td>CEsr-2663400</td><td>0.64</td><td>36.69</td><td>-0.04</td><td>33:30:06</td><td>-3.31</td></tr><tr><td>CEsr-2638300</td><td>0.64</td><td>37.70</td><td>2.69</td><td>37:10:33</td><td>0.37</td></tr><tr><td>CEsr-1332700</td><td>0.64</td><td>36.29</td><td>-1.13</td><td>34:22:16</td><td>-2.44</td></tr><tr><td>CEsr-3466000</td><td>0.64</td><td>30.87</td><td>-15.91</td><td>32:49:35</td><td>-3.98</td></tr><tr><td>CEsr-5930000</td><td>0.64</td><td>36.76</td><td>0.14</td><td>35:09:34</td><td>-1.65</td></tr><tr><td>CEsr-6389000</td><td>0.64</td><td>37.79</td><td>2.94</td><td>37:22:46</td><td>0.57</td></tr><tr><td>CEsr-6157000</td><td>0.64</td><td>43.40</td><td>18.25</td><td>35:26:12</td><td>-1.37</td></tr><tr><td>CEsr-2612000</td><td>0.64</td><td>35.67</td><td>-2.82</td><td>33:37:48</td><td>-3.18</td></tr><tr><td>CEsr-5941000</td><td>0.64</td><td>43.26</td><td>17.86</td><td>34:25:59</td><td>-2.38</td></tr><tr><td>CEsr-3142000</td><td>0.64</td><td>35.26</td><td>-3.93</td><td>36:46:48</td><td>-0.03</td></tr><tr><td>CEsr-6811000</td><td>0.64</td><td>33.69</td><td>-8.21</td><td>28:29:39</td><td>-8.32</td></tr><tr><td>CEsr-2551900</td><td>0.64</td><td>42.30</td><td>15.25</td><td>36:37:25</td><td>-0.19</td></tr><tr><td>CEsr-7030000</td><td>0.64</td><td>36.67</td><td>-0.09</td><td>33:59:27</td><td>-2.82</td></tr><tr><td>CEsr-4917000</td><td>0.64</td><td>39.11</td><td>6.55</td><td>36:00:21</td><td>-0.80</td></tr><tr><td>CEsr-1692000</td><td>0.64</td><td>45.51</td><td>23.99</td><td>36:58:17</td><td>0.16</td></tr><tr><td>CEsr-5907000</td><td>0.64</td><td>39.07</td><td>6.44</td><td>34:19:43</td><td>-2.48</td></tr><tr><td>CEsr-1417000</td><td>0.64</td><td>36.29</td><td>-1.14</td><td>34:08:00</td><td>-2.68</td></tr><tr><td>CEsr-3557000</td><td>0.64</td><td>31.10</td><td>-15.27</td><td>33:35:47</td><td>-3.21</td></tr><tr><td>CEsr-3813000</td><td>0.64</td><td>39.71</td><td>8.17</td><td>39:06:01</td><td>2.29</td></tr><tr><td>CEsr-3855000</td><td>0.64</td><td>52.83</td><td>43.93</td><td>43:23:37</td><td>6.58</td></tr><tr><td>CEsr-1303000</td><td>0.64</td><td>40.43</td><td>10.14</td><td>36:01:55</td><td>-0.78</td></tr><tr><td>CEsr-4397000</td><td>0.64</td><td>36.58</td><td>-0.36</td><td>33:35:28</td><td>-3.22</td></tr><tr><td>CEsr-4966000</td><td>0.64</td><td>40.24</td><td>9.62</td><td>36:32:33</td><td>-0.27</td></tr><tr><td>CEsr-1435000</td><td>0.64</td><td>35.92</td><td>-2.14</td><td>35:21:53</td><td>-1.45</td></tr><tr><td>CEsr-2805000</td><td>0.64</td><td>47.79</td><td>30.20</td><td>37:08:17</td><td>0.33</td></tr><tr><td>CEsr-3922000</td><td>0.64</td><td>40.59</td><td>10.59</td><td>35:00:00</td><td>-1.81</td></tr><tr><td>CEsr-4151000</td><td>0.64</td><td>39.16</td><td>6.68</td><td>39:08:22</td><td>2.33</td></tr><tr><td>CEsr-3370500</td><td>0.64</td><td>49.82</td><td>35.73</td><td>39:38:11</td><td>2.83</td></tr><tr><td>CEsr-1870900</td><td>0.64</td><td>43.84</td><td>19.44</td><td>36:07:37</td><td>-0.68</td></tr><tr><td>CEsr-7265000</td><td>0.64</td><td>40.40</td><td>10.06</td><td>35:08:43</td><td>-1.66</td></tr><tr><td>CEsr-2570400</td><td>0.64</td><td>40.71</td><td>10.92</td><td>35:03:55</td><td>-1.74</td></tr><tr><td>CEsr-5730000</td><td>0.64</td><td>39.51</td><td>7.63</td><td>35:34:34</td><td>-1.23</td></tr><tr><td>CEsr-5642000</td><td>0.64</td><td>41.51</td><td>13.08</td><td>34:06:28</td><td>-2.70</td></tr><tr><td>CEsr-3189800</td><td>0.64</td><td>24.98</td><td>-31.94</td><td>17:58:35</td><td>-18.83</td></tr><tr><td>CEsr-2661100</td><td>0.64</td><td>49.63</td><td>35.22</td><td>42:52:05</td><td>6.06</td></tr><tr><td>C14 untreated mock-infected cells</td><td>0.64</td><td>138.85 ± 4.39</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C14 untreated infected cells</td><td>0.64</td><td>42.15 ± 7.36</td><td>N.D</td><td>33:54:55</td><td>N.D</td></tr><tr><td>CEsr-4006000</td><td>0.64</td><td>36.51</td><td>-13.39</td><td>36:00:30</td><td>-0.38</td></tr><tr><td>CEsr-2583800</td><td>0.64</td><td>43.59</td><td>3.42</td><td>37:01:19</td><td>0.64</td></tr><tr><td>CEsr-3993000</td><td>0.64</td><td>37.95</td><td>-9.98</td><td>37:07:49</td><td>0.74</td></tr><tr><td>CEsr-4025000</td><td>0.64</td><td>38.13</td><td>-9.56</td><td>34:42:22</td><td>-1.68</td></tr><tr><td>CEsr-2038500</td><td>0.64</td><td>39.30</td><td>-6.76</td><td>37:07:33</td><td>0.74</td></tr><tr><td>CEsr-2325000</td><td>0.64</td><td>46.24</td><td>9.69</td><td>36:55:28</td><td>0.54</td></tr><tr><td>CEsr-4024000</td><td>0.64</td><td>37.98</td><td>-9.90</td><td>35:51:21</td><td>-0.53</td></tr><tr><td>CEsr-3519000</td><td>0.64</td><td>42.58</td><td>1.01</td><td>38:52:30</td><td>2.49</td></tr><tr><td>CEsr-2585600</td><td>0.64</td><td>46.70</td><td>10.79</td><td>40:52:16</td><td>4.48</td></tr><tr><td>CEsr-3956000</td><td>0.64</td><td>38.66</td><td>-8.28</td><td>35:15:11</td><td>-1.13</td></tr><tr><td>CEsr-5838000</td><td>0.64</td><td>45.60</td><td>8.17</td><td>36:53:09</td><td>0.50</td></tr><tr><td>CEsr-1544600</td><td>0.64</td><td>36.62</td><td>-13.12</td><td>34:47:58</td><td>-1.59</td></tr><tr><td>CEsr-3064600</td><td>0.64</td><td>42.54</td><td>0.93</td><td>35:19:22</td><td>-1.06</td></tr><tr><td>CEsr-1013000</td><td>0.64</td><td>39.71</td><td>-5.80</td><td>39:34:24</td><td>3.19</td></tr><tr><td>CEsr-3975000</td><td>0.64</td><td>45.17</td><td>7.16</td><td>38:55:49</td><td>2.54</td></tr><tr><td>CEsr-1685000</td><td>0.64</td><td>20.39</td><td>-51.62</td><td>34:42:23</td><td>-1.68</td></tr><tr><td>CEsr-6465000</td><td>0.64</td><td>38.82</td><td>-7.90</td><td>36:00:53</td><td>-0.37</td></tr><tr><td>CEsr-3393900</td><td>0.64</td><td>43.14</td><td>2.35</td><td>36:03:57</td><td>-0.32</td></tr><tr><td>CEsr-1846900</td><td>0.64</td><td>41.34</td><td>-1.93</td><td>36:20:25</td><td>-0.05</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEmr-3081900</td><td>0.64</td><td>43.35</td><td>2.83</td><td>38:07:04</td><td>1.73</td></tr><tr><td>CESr-6222000</td><td>0.64</td><td>40.52</td><td>-3.88</td><td>35:17:09</td><td>-1.10</td></tr><tr><td>CEmr-2553900</td><td>0.64</td><td>38.63</td><td>-8.36</td><td>34:50:31</td><td>-1.54</td></tr><tr><td>CEmr-2507800</td><td>0.64</td><td>44.86</td><td>6.42</td><td>41:44:42</td><td>5.36</td></tr><tr><td>CEmr-2581900</td><td>0.64</td><td>46.93</td><td>11.34</td><td>40:02:36</td><td>3.66</td></tr><tr><td>CEmr-2571900</td><td>0.64</td><td>36.84</td><td>-12.61</td><td>33:46:53</td><td>-2.60</td></tr><tr><td>CEmr-2372800</td><td>0.64</td><td>41.07</td><td>-2.56</td><td>38:56:17</td><td>2.55</td></tr><tr><td>CESr-2668000</td><td>0.64</td><td>40.20</td><td>-4.62</td><td>34:45:04</td><td>-1.64</td></tr><tr><td>CESr-4953000</td><td>0.64</td><td>40.88</td><td>-3.02</td><td>35:44:33</td><td>-0.64</td></tr><tr><td>CEmr-2241000</td><td>0.64</td><td>44.28</td><td>5.05</td><td>42:10:02</td><td>5.78</td></tr><tr><td>CESr-7232000</td><td>0.64</td><td>41.30</td><td>-2.02</td><td>34:15:24</td><td>-2.13</td></tr><tr><td>CESr-5090000</td><td>0.64</td><td>36.18</td><td>-14.18</td><td>34:13:27</td><td>-2.16</td></tr><tr><td>CESr-1485000</td><td>0.64</td><td>41.85</td><td>-0.71</td><td>39:02:39</td><td>2.66</td></tr><tr><td>CESr-3006000</td><td>0.64</td><td>38.47</td><td>-8.74</td><td>36:27:09</td><td>0.07</td></tr><tr><td>CESr-1537000</td><td>0.64</td><td>36.76</td><td>-12.79</td><td>33:42:46</td><td>-2.67</td></tr><tr><td>CEmr-8283000</td><td>0.64</td><td>46.63</td><td>10.62</td><td>34:43:17</td><td>-1.67</td></tr><tr><td>CESr-5969000</td><td>0.64</td><td>36.06</td><td>-14.46</td><td>32:57:48</td><td>-3.42</td></tr><tr><td>CESr-4485000</td><td>0.64</td><td>35.32</td><td>-16.21</td><td>32:34:13</td><td>-3.82</td></tr><tr><td>CESr-1883000</td><td>0.64</td><td>40.32</td><td>-4.35</td><td>35:23:21</td><td>-1.00</td></tr><tr><td>CEnap-2000000</td><td>0.64</td><td>36.74</td><td>-12.84</td><td>34:56:25</td><td>-1.45</td></tr><tr><td>CEmr-2631700</td><td>0.64</td><td>41.70</td><td>-1.09</td><td>38:53:15</td><td>2.50</td></tr><tr><td>CEmr-2506400</td><td>0.64</td><td>45.30</td><td>7.45</td><td>38:06:34</td><td>1.72</td></tr><tr><td>CESr-2694000</td><td>0.64</td><td>39.35</td><td>-6.65</td><td>34:41:58</td><td>-1.69</td></tr><tr><td>CESr-4526000</td><td>0.64</td><td>40.85</td><td>-3.08</td><td>36:19:28</td><td>-0.06</td></tr><tr><td>CESr-3419000</td><td>0.64</td><td>34.38</td><td>-18.43</td><td>31:54:01</td><td>-4.49</td></tr><tr><td>CEmr-2147000</td><td>0.64</td><td>38.12</td><td>-9.56</td><td>34:27:52</td><td>-1.92</td></tr><tr><td>CEmr-2800500</td><td>0.64</td><td>43.19</td><td>2.47</td><td>34:15:39</td><td>-2.13</td></tr><tr><td>CESr-2494000</td><td>0.64</td><td>31.02</td><td>-26.40</td><td>33:24:39</td><td>-2.98</td></tr><tr><td>CESr-1693000</td><td>0.64</td><td>41.20</td><td>-2.26</td><td>36:36:50</td><td>0.23</td></tr><tr><td>CEmr-3228000</td><td>0.64</td><td>42.35</td><td>0.46</td><td>35:45:06</td><td>-0.63</td></tr><tr><td>CESr-2611000</td><td>0.64</td><td>43.01</td><td>2.02</td><td>36:58:39</td><td>0.59</td></tr><tr><td>CESr-2614000</td><td>0.64</td><td>37.92</td><td>-10.05</td><td>37:47:08</td><td>1.40</td></tr><tr><td>CEmr-2230000</td><td>0.64</td><td>38.69</td><td>-8.21</td><td>34:19:23</td><td>-2.06</td></tr><tr><td>CESr-1778000</td><td>0.64</td><td>38.58</td><td>-8.47</td><td>34:22:54</td><td>-2.00</td></tr><tr><td>CESr-1851000</td><td>0.64</td><td>38.97</td><td>-7.56</td><td>35:26:14</td><td>-0.95</td></tr><tr><td>CESr-1822000</td><td>0.64</td><td>39.00</td><td>-7.48</td><td>36:49:10</td><td>0.43</td></tr><tr><td>CESr-1752000</td><td>0.64</td><td>39.74</td><td>-5.73</td><td>38:23:49</td><td>2.01</td></tr><tr><td>CEmr-2708200</td><td>0.64</td><td>37.79</td><td>-10.36</td><td>36:48:10</td><td>0.42</td></tr><tr><td>CESr-6311000</td><td>0.64</td><td>37.15</td><td>-11.86</td><td>34:46:16</td><td>-1.62</td></tr><tr><td>CESr-6012000</td><td>0.64</td><td>33.47</td><td>-20.59</td><td>34:56:29</td><td>-1.45</td></tr><tr><td>CESr-1829000</td><td>0.64</td><td>42.95</td><td>1.88</td><td>34:22:23</td><td>-2.01</td></tr><tr><td>CEmr-3223100</td><td>0.64</td><td>43.85</td><td>4.03</td><td>40:16:33</td><td>3.89</td></tr><tr><td>CESr-3839000</td><td>0.64</td><td>40.67</td><td>-3.52</td><td>36:12:04</td><td>-0.19</td></tr><tr><td>CESr-1837000</td><td>0.64</td><td>42.04</td><td>-0.26</td><td>36:23:34</td><td>0.01</td></tr><tr><td>CEmr-3222800</td><td>0.64</td><td>39.00</td><td>-7.49</td><td>38:16:42</td><td>1.89</td></tr><tr><td>CEmr-3463800</td><td>0.64</td><td>36.71</td><td>-12.92</td><td>37:36:32</td><td>1.22</td></tr><tr><td>CEmr-2613900</td><td>0.64</td><td>39.41</td><td>-6.51</td><td>37:10:27</td><td>0.79</td></tr><tr><td>CEmr-3464000</td><td>0.64</td><td>17.92</td><td>-57.49</td><td>20:26:01</td><td>-15.95</td></tr><tr><td>CEmr-3413400</td><td>0.64</td><td>39.20</td><td>-7.01</td><td>35:15:44</td><td>-1.12</td></tr><tr><td>CESr-6888000</td><td>0.64</td><td>35.97</td><td>-14.68</td><td>33:25:35</td><td>-2.96</td></tr><tr><td>CEmr-2575300</td><td>0.64</td><td>38.54</td><td>-8.56</td><td>35:37:17</td><td>-0.77</td></tr><tr><td>CEmr-2614000</td><td>0.64</td><td>42.30</td><td>0.35</td><td>35:07:42</td><td>-1.26</td></tr><tr><td>CEmr-3274200</td><td>0.64</td><td>25.85</td><td>-38.68</td><td>33:28:27</td><td>-2.91</td></tr><tr><td>CEmr-3462400</td><td>0.64</td><td>38.55</td><td>-8.55</td><td>37:26:55</td><td>1.06</td></tr><tr><td>CEmr-3461000</td><td>0.64</td><td>39.36</td><td>-6.62</td><td>38:54:59</td><td>2.53</td></tr><tr><td>CEmr-3268100</td><td>0.64</td><td>32.58</td><td>-22.72</td><td>32:03:43</td><td>-4.32</td></tr><tr><td>CEmr-3337700</td><td>0.64</td><td>37.56</td><td>-10.90</td><td>36:18:30</td><td>-0.08</td></tr><tr><td>CEmr-2708400</td><td>0.64</td><td>35.28</td><td>-16.31</td><td>34:18:31</td><td>-2.08</td></tr><tr><td>CEmr-3271600</td><td>0.64</td><td>34.40</td><td>-18.40</td><td>34:40:38</td><td>-1.71</td></tr><tr><td>CEmr-3272000</td><td>0.64</td><td>29.68</td><td>-29.60</td><td>30:23:28</td><td>-6.00</td></tr><tr><td>CEmr-3463400</td><td>0.64</td><td>37.16</td><td>-11.85</td><td>34:44:20</td><td>-1.65</td></tr><tr><td>C15 untreated mock-infected cells</td><td>0.69</td><td>150.10 ± 8.93</td><td>N.D</td><td>N.D</td><td>N.D</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>C15 untreated infected cells</td><td>0.69</td><td>52.67 ± 1.16</td><td>N.D</td><td>41:12:09</td><td>N.D</td></tr><tr><td>CEmr-2301300</td><td>0.69</td><td>43.94</td><td>-16.58</td><td>38:12:40</td><td>-4.61</td></tr><tr><td>CEmr-7299000</td><td>0.69</td><td>49.50</td><td>-6.01</td><td>37:43:18</td><td>-5.10</td></tr><tr><td>CEmr-3053500</td><td>0.69</td><td>47.47</td><td>-9.88</td><td>39:18:17</td><td>-3.52</td></tr><tr><td>CEmr-5912000</td><td>0.69</td><td>47.44</td><td>-9.93</td><td>40:57:34</td><td>-1.87</td></tr><tr><td>CEmr-2707500</td><td>0.69</td><td>44.95</td><td>-14.65</td><td>41:21:42</td><td>-1.46</td></tr><tr><td>CEmr-2331800</td><td>0.69</td><td>43.48</td><td>-17.44</td><td>40:49:34</td><td>-2.00</td></tr><tr><td>CEmr-2518000</td><td>0.69</td><td>58.31</td><td>10.72</td><td>45:49:10</td><td>2.99</td></tr><tr><td>CEmr-1622200</td><td>0.69</td><td>46.77</td><td>-11.21</td><td>38:17:35</td><td>-4.53</td></tr><tr><td>CEmr-2646000</td><td>0.69</td><td>38.61</td><td>-26.69</td><td>38:03:05</td><td>-4.77</td></tr><tr><td>CEmr-2649000</td><td>0.69</td><td>54.90</td><td>4.24</td><td>43:18:35</td><td>0.48</td></tr><tr><td>CEmr-5516000</td><td>0.69</td><td>50.26</td><td>-4.58</td><td>41:03:18</td><td>-1.77</td></tr><tr><td>CEmr-1832000</td><td>0.69</td><td>47.40</td><td>-10.01</td><td>43:35:41</td><td>0.77</td></tr><tr><td>CEmr-7304000</td><td>0.69</td><td>45.33</td><td>-13.93</td><td>39:51:35</td><td>-2.97</td></tr><tr><td>CEmr-3052700</td><td>0.69</td><td>48.97</td><td>-7.03</td><td>40:55:23</td><td>-1.90</td></tr><tr><td>CEmr-7155000</td><td>0.69</td><td>48.66</td><td>-7.61</td><td>41:33:01</td><td>-1.28</td></tr><tr><td>CEmr-4927000</td><td>0.69</td><td>48.65</td><td>-7.63</td><td>39:37:54</td><td>-3.19</td></tr><tr><td>CEmr-3414000</td><td>0.69</td><td>47.39</td><td>-10.02</td><td>40:06:08</td><td>-2.72</td></tr><tr><td>CEmr-6870000</td><td>0.69</td><td>49.33</td><td>-6.34</td><td>41:51:13</td><td>-0.97</td></tr><tr><td>CEmr-2284300</td><td>0.69</td><td>49.43</td><td>-6.14</td><td>42:08:35</td><td>-0.68</td></tr><tr><td>CEmr-2640000</td><td>0.69</td><td>46.94</td><td>-10.88</td><td>41:28:11</td><td>-1.36</td></tr><tr><td>CEmr-1808000</td><td>0.69</td><td>48.74</td><td>-7.47</td><td>41:43:42</td><td>-1.10</td></tr><tr><td>CEmr-3405000</td><td>0.69</td><td>48.15</td><td>-8.58</td><td>39:47:06</td><td>-3.04</td></tr><tr><td>CEmr-2320000</td><td>0.69</td><td>43.89</td><td>-16.67</td><td>39:01:01</td><td>-3.81</td></tr><tr><td>CEmr-1517000</td><td>0.69</td><td>47.70</td><td>-9.44</td><td>40:51:37</td><td>-1.97</td></tr><tr><td>CEmr-3399000</td><td>0.69</td><td>51.76</td><td>-1.73</td><td>41:08:39</td><td>-1.68</td></tr><tr><td>CEmr-4438000</td><td>0.69</td><td>48.93</td><td>-7.10</td><td>39:34:41</td><td>-3.25</td></tr><tr><td>CEmr-4625000</td><td>0.69</td><td>46.78</td><td>-11.18</td><td>40:42:08</td><td>-2.12</td></tr><tr><td>CEmr-4422000</td><td>0.69</td><td>46.49</td><td>-11.74</td><td>39:34:36</td><td>-3.25</td></tr><tr><td>CEmr-4495000</td><td>0.69</td><td>51.93</td><td>-1.41</td><td>41:21:49</td><td>-1.46</td></tr><tr><td>CEmr-5809000</td><td>0.69</td><td>49.74</td><td>-5.56</td><td>40:38:30</td><td>-2.18</td></tr><tr><td>CEmr-1229000</td><td>0.69</td><td>49.54</td><td>-5.94</td><td>40:53:35</td><td>-1.93</td></tr><tr><td>CEmr-4364000</td><td>0.69</td><td>45.83</td><td>-12.98</td><td>38:50:51</td><td>-3.98</td></tr><tr><td>CEmr-1845600</td><td>0.69</td><td>43.30</td><td>-17.78</td><td>38:30:53</td><td>-4.31</td></tr><tr><td>CEmr-4639000</td><td>0.69</td><td>44.13</td><td>-16.21</td><td>40:28:55</td><td>-2.34</td></tr><tr><td>CEmr-2554300</td><td>0.69</td><td>48.03</td><td>-8.81</td><td>38:58:53</td><td>-3.84</td></tr><tr><td>CEmr-5747000</td><td>0.69</td><td>53.33</td><td>1.25</td><td>45:21:13</td><td>2.53</td></tr><tr><td>CEmr-4622000</td><td>0.69</td><td>47.58</td><td>-9.67</td><td>39:09:39</td><td>-3.67</td></tr><tr><td>CEmr-3634000</td><td>0.69</td><td>50.17</td><td>-4.75</td><td>42:48:52</td><td>-0.01</td></tr><tr><td>CEmr-2639000</td><td>0.69</td><td>46.88</td><td>-11.00</td><td>38:34:16</td><td>-4.25</td></tr><tr><td>CEmr-4195000</td><td>0.69</td><td>48.48</td><td>-7.96</td><td>39:11:03</td><td>-3.64</td></tr><tr><td>CEmr-4482000</td><td>0.69</td><td>47.79</td><td>-9.26</td><td>41:38:25</td><td>-1.19</td></tr><tr><td>CEmr-4175000</td><td>0.69</td><td>53.04</td><td>0.71</td><td>41:36:24</td><td>-1.22</td></tr><tr><td>CEmr-hm18900</td><td>0.69</td><td>44.76</td><td>-15.01</td><td>39:31:16</td><td>-3.30</td></tr><tr><td>CEmr-3624000</td><td>0.69</td><td>47.11</td><td>-10.56</td><td>43:16:19</td><td>0.45</td></tr><tr><td>CEmr-4146000</td><td>0.69</td><td>50.11</td><td>-4.86</td><td>40:51:09</td><td>-1.97</td></tr><tr><td>CEmr-4193000</td><td>0.69</td><td>49.47</td><td>-6.08</td><td>38:54:35</td><td>-3.92</td></tr><tr><td>CEmr-4368000</td><td>0.69</td><td>39.14</td><td>-25.69</td><td>38:18:22</td><td>-4.52</td></tr><tr><td>CEmr-3838000</td><td>0.69</td><td>53.35</td><td>1.30</td><td>41:18:48</td><td>-1.51</td></tr><tr><td>CEmr-4149000</td><td>0.69</td><td>41.20</td><td>-21.78</td><td>37:48:38</td><td>-5.02</td></tr><tr><td>CEmr-1812500</td><td>0.69</td><td>55.48</td><td>5.34</td><td>46:11:20</td><td>3.36</td></tr><tr><td>CEmr-3184900</td><td>0.69</td><td>37.77</td><td>-28.28</td><td>40:30:14</td><td>-2.32</td></tr><tr><td>CEmr-4165000</td><td>0.69</td><td>52.24</td><td>-0.81</td><td>42:52:21</td><td>0.05</td></tr><tr><td>CEmr-3681000</td><td>0.69</td><td>51.15</td><td>-2.89</td><td>43:37:46</td><td>0.80</td></tr><tr><td>CEmr-7324000</td><td>0.69</td><td>33.57</td><td>-36.27</td><td>17:38:10</td><td>-25.19</td></tr><tr><td>CEmr-2004000</td><td>0.69</td><td>49.05</td><td>-6.87</td><td>40:11:48</td><td>-2.63</td></tr><tr><td>CEmr-1407201</td><td>0.69</td><td>48.76</td><td>-7.41</td><td>39:26:54</td><td>-3.38</td></tr><tr><td>CEmr-6085000</td><td>0.69</td><td>48.85</td><td>-7.25</td><td>40:36:52</td><td>-2.21</td></tr><tr><td>CEmr-14500000</td><td>0.69</td><td>41.35</td><td>-21.50</td><td>43:46:46</td><td>0.95</td></tr><tr><td>CEmr-2636700</td><td>0.69</td><td>44.47</td><td>-15.57</td><td>43:18:34</td><td>0.48</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CESr-618000</td><td>0.69</td><td>53.20</td><td>1.01</td><td>42:58:44</td><td>0.15</td></tr><tr><td>CESr-5813000</td><td>0.69</td><td>52.87</td><td>0.37</td><td>43:33:16</td><td>0.73</td></tr><tr><td>CESr-6239000</td><td>0.69</td><td>49.21</td><td>-6.57</td><td>40:52:28</td><td>-1.95</td></tr><tr><td>CESr-5683000</td><td>0.69</td><td>51.29</td><td>-2.62</td><td>47:53:25</td><td>5.06</td></tr><tr><td>CESr-1867000</td><td>0.69</td><td>52.67</td><td>0.00</td><td>38:17:44</td><td>-4.53</td></tr><tr><td>CESr-2032000</td><td>0.69</td><td>52.01</td><td>-1.26</td><td>38:12:40</td><td>-4.61</td></tr><tr><td>CEmr-1607700</td><td>0.69</td><td>60.55</td><td>14.97</td><td>47:38:57</td><td>4.82</td></tr><tr><td>CESr-5582000</td><td>0.69</td><td>50.81</td><td>-3.53</td><td>40:46:20</td><td>-2.05</td></tr><tr><td>CEmr-2703200</td><td>0.69</td><td>54.10</td><td>2.72</td><td>43:45:15</td><td>0.93</td></tr><tr><td>CEmr-2037700</td><td>0.69</td><td>53.09</td><td>0.80</td><td>42:25:36</td><td>-0.40</td></tr><tr><td>CESr-5358000</td><td>0.69</td><td>37.70</td><td>-28.42</td><td>38:00:16</td><td>-4.82</td></tr><tr><td>CESr-5682000</td><td>0.69</td><td>51.68</td><td>-1.88</td><td>40:34:39</td><td>-2.25</td></tr><tr><td>CESr-1186000</td><td>0.69</td><td>52.99</td><td>0.60</td><td>40:56:52</td><td>-1.88</td></tr><tr><td>CESr-4088000</td><td>0.69</td><td>48.14</td><td>-8.60</td><td>41:24:45</td><td>-1.41</td></tr><tr><td>CEmr-1214300</td><td>0.69</td><td>50.56</td><td>-4.01</td><td>40:57:23</td><td>-1.87</td></tr><tr><td>CEmr-2533200</td><td>0.69</td><td>53.03</td><td>0.68</td><td>43:06:13</td><td>0.28</td></tr><tr><td>CEmr-3220100</td><td>0.69</td><td>30.75</td><td>-41.62</td><td>5:28:30</td><td>-37.35</td></tr><tr><td>CESr-2061000</td><td>0.69</td><td>52.38</td><td>-0.55</td><td>43:37:40</td><td>0.80</td></tr><tr><td>CESr-1572000</td><td>0.69</td><td>54.38</td><td>3.25</td><td>43:51:26</td><td>1.03</td></tr><tr><td>CESr-1337000</td><td>0.69</td><td>41.02</td><td>-22.12</td><td>37:23:07</td><td>-5.44</td></tr><tr><td>CESr-6226000</td><td>0.69</td><td>51.42</td><td>-2.38</td><td>43:46:55</td><td>0.96</td></tr><tr><td>C16 untreated mock-infected cells</td><td>0.66</td><td>138.98 ± 6.86</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C16 untreated infected cells</td><td>0.66</td><td>51.37 ± 3.05</td><td>N.D</td><td>40:03:01</td><td>N.D</td></tr><tr><td>CEmr-3200100</td><td>0.66</td><td>49.39</td><td>-3.86</td><td>42:22:03</td><td>-1.05</td></tr><tr><td>CESr-2746000</td><td>0.66</td><td>56.36</td><td>9.72</td><td>41:08:17</td><td>-2.28</td></tr><tr><td>CESr-4155000</td><td>0.66</td><td>45.81</td><td>-10.83</td><td>40:31:10</td><td>-2.90</td></tr><tr><td>CEmr-1943200</td><td>0.66</td><td>52.69</td><td>2.57</td><td>45:19:47</td><td>1.92</td></tr><tr><td>Cepa-46</td><td>0.66</td><td>45.05</td><td>-12.31</td><td>39:56:25</td><td>-3.47</td></tr><tr><td>CESr-1927000</td><td>0.66</td><td>52.75</td><td>2.68</td><td>46:57:18</td><td>3.54</td></tr><tr><td>Cepa-65</td><td>0.66</td><td>50.00</td><td>-2.66</td><td>42:51:40</td><td>-0.55</td></tr><tr><td>CESr-2801000</td><td>0.66</td><td>42.81</td><td>-16.67</td><td>42:40:35</td><td>-0.74</td></tr><tr><td>CESr-5799000</td><td>0.66</td><td>47.83</td><td>-6.88</td><td>38:54:57</td><td>-4.50</td></tr><tr><td>CEmr-2023600</td><td>0.66</td><td>55.62</td><td>8.26</td><td>45:13:43</td><td>1.81</td></tr><tr><td>CESr-7045000</td><td>0.66</td><td>53.42</td><td>3.99</td><td>44:06:30</td><td>0.69</td></tr><tr><td>CESr-6310000</td><td>0.66</td><td>49.92</td><td>-2.83</td><td>43:08:22</td><td>-0.28</td></tr><tr><td>CESr-7453000</td><td>0.66</td><td>46.43</td><td>-9.61</td><td>41:58:50</td><td>-1.43</td></tr><tr><td>CESr-2153000</td><td>0.66</td><td>45.15</td><td>-12.11</td><td>42:51:17</td><td>-0.56</td></tr><tr><td>CESr-3747000</td><td>0.66</td><td>52.94</td><td>3.06</td><td>41:09:32</td><td>-2.26</td></tr><tr><td>CESr-2437000</td><td>0.66</td><td>51.94</td><td>1.10</td><td>38:37:10</td><td>-4.80</td></tr><tr><td>CEmr-1618400</td><td>0.66</td><td>44.64</td><td>-13.10</td><td>37:41:51</td><td>-5.72</td></tr><tr><td>CESr-1291000</td><td>0.66</td><td>50.69</td><td>-1.32</td><td>42:22:17</td><td>-1.04</td></tr><tr><td>CESr-6521000</td><td>0.66</td><td>46.79</td><td>-8.92</td><td>40:04:18</td><td>-3.34</td></tr><tr><td>CESr-6283000</td><td>0.66</td><td>46.07</td><td>-10.32</td><td>41:09:09</td><td>-2.26</td></tr><tr><td>CESr-7442000</td><td>0.66</td><td>46.12</td><td>-10.23</td><td>41:13:28</td><td>-2.19</td></tr><tr><td>CESr-5723000</td><td>0.66</td><td>45.52</td><td>-11.39</td><td>41:10:17</td><td>-2.24</td></tr><tr><td>CESr-1130000</td><td>0.66</td><td>42.95</td><td>-16.40</td><td>38:59:06</td><td>-4.43</td></tr><tr><td>CESr-3100000</td><td>0.66</td><td>49.67</td><td>-3.31</td><td>43:34:04</td><td>0.15</td></tr><tr><td>CESr-1107000</td><td>0.66</td><td>37.53</td><td>-26.94</td><td>41:54:24</td><td>-1.51</td></tr><tr><td>CESr-1324000</td><td>0.66</td><td>51.29</td><td>-0.16</td><td>43:09:24</td><td>-0.26</td></tr><tr><td>CEmr-1634500</td><td>0.66</td><td>45.77</td><td>-10.90</td><td>40:13:28</td><td>-3.19</td></tr><tr><td>CESr-1625000</td><td>0.66</td><td>50.69</td><td>-1.33</td><td>46:02:14</td><td>2.62</td></tr><tr><td>CESr-4243000</td><td>0.66</td><td>54.36</td><td>5.82</td><td>42:19:09</td><td>-1.10</td></tr><tr><td>CESr-5674000</td><td>0.66</td><td>45.45</td><td>-11.52</td><td>39:18:44</td><td>-4.10</td></tr><tr><td>CESr-3337000</td><td>0.66</td><td>49.65</td><td>-3.35</td><td>39:25:13</td><td>-3.99</td></tr><tr><td>CESr-3328000</td><td>0.66</td><td>44.34</td><td>-13.69</td><td>37:49:45</td><td>-5.59</td></tr><tr><td>CESr-1156000</td><td>0.66</td><td>46.82</td><td>-8.86</td><td>38:21:37</td><td>-5.05</td></tr><tr><td>CESr-3395000</td><td>0.66</td><td>46.04</td><td>-10.37</td><td>40:22:00</td><td>-3.05</td></tr><tr><td>CEmr-2094200</td><td>0.66</td><td>48.59</td><td>-5.41</td><td>40:40:42</td><td>-2.74</td></tr><tr><td>CEmr-hm68400</td><td>0.66</td><td>48.02</td><td>-6.51</td><td>42:07:42</td><td>-1.29</td></tr><tr><td>CEmr-1289300</td><td>0.66</td><td>58.96</td><td>14.77</td><td>39:55:49</td><td>-3.48</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEmr-2291300</td><td>0.66</td><td>44.55</td><td>-13.28</td><td>41:35:43</td><td>-1.82</td></tr><tr><td>CESr-4078000</td><td>0.66</td><td>47.21</td><td>-8.10</td><td>40:46:48</td><td>-2.63</td></tr><tr><td>CEmr-1615300</td><td>0.66</td><td>53.39</td><td>3.93</td><td>42:14:00</td><td>-1.18</td></tr><tr><td>CEsr-3560000</td><td>0.66</td><td>54.34</td><td>5.78</td><td>44:13:07</td><td>0.80</td></tr><tr><td>CEsr-4135000</td><td>0.66</td><td>57.59</td><td>12.11</td><td>43:39:59</td><td>0.25</td></tr><tr><td>CEmr-2332900</td><td>0.66</td><td>54.80</td><td>6.68</td><td>43:40:55</td><td>0.27</td></tr><tr><td>CEmr-1613500</td><td>0.66</td><td>40.63</td><td>-20.92</td><td>41:22:10</td><td>-2.05</td></tr><tr><td>CEsr-3623000</td><td>0.66</td><td>39.38</td><td>-23.34</td><td>43:34:18</td><td>0.16</td></tr><tr><td>CEsr-4169000</td><td>0.66</td><td>31.88</td><td>-37.93</td><td>38:32:34</td><td>-4.87</td></tr><tr><td>CEsr-3324000</td><td>0.66</td><td>37.19</td><td>-27.61</td><td>37:04:12</td><td>-6.34</td></tr><tr><td>CEsr-1748000</td><td>0.66</td><td>50.12</td><td>-2.43</td><td>39:06:54</td><td>-4.30</td></tr><tr><td>CEsr-6578000</td><td>0.66</td><td>55.26</td><td>7.58</td><td>38:43:19</td><td>-4.69</td></tr><tr><td>CEmr-2607000</td><td>0.66</td><td>50.41</td><td>-1.86</td><td>39:11:26</td><td>-4.22</td></tr><tr><td>CEmr-2774900</td><td>0.66</td><td>48.54</td><td>-5.52</td><td>39:54:02</td><td>-3.51</td></tr><tr><td>CEmr-2776200</td><td>0.66</td><td>51.31</td><td>-0.11</td><td>41:24:08</td><td>-2.01</td></tr><tr><td>CEmr-2248200</td><td>0.66</td><td>47.14</td><td>-8.23</td><td>41:27:34</td><td>-1.96</td></tr><tr><td>CEmr-2466700</td><td>0.66</td><td>57.61</td><td>12.14</td><td>45:46:15</td><td>2.36</td></tr><tr><td>CEmr-2667700</td><td>0.66</td><td>46.92</td><td>-8.67</td><td>40:18:08</td><td>-3.11</td></tr><tr><td>CEmr-2024900</td><td>0.66</td><td>49.60</td><td>-3.45</td><td>40:06:18</td><td>-3.31</td></tr><tr><td>CEmr-2320500</td><td>0.66</td><td>47.03</td><td>-8.45</td><td>39:42:26</td><td>-3.71</td></tr><tr><td>CEmr-2025800</td><td>0.66</td><td>48.67</td><td>-5.26</td><td>42:04:38</td><td>-1.34</td></tr><tr><td>CEsr-6836000</td><td>0.66</td><td>42.17</td><td>-17.90</td><td>40:57:51</td><td>-2.45</td></tr><tr><td>CEmr-2603400</td><td>0.66</td><td>32.50</td><td>-36.74</td><td>38:23:40</td><td>-5.02</td></tr><tr><td>CEmr-2607100</td><td>0.66</td><td>44.62</td><td>-13.13</td><td>41:33:56</td><td>-1.85</td></tr><tr><td>CEsr-6617000</td><td>0.66</td><td>51.58</td><td>0.42</td><td>41:05:20</td><td>-2.33</td></tr><tr><td>CEmr-2090400</td><td>0.66</td><td>46.60</td><td>-9.29</td><td>40:00:03</td><td>-3.41</td></tr><tr><td>CEsr-2590000</td><td>0.66</td><td>51.31</td><td>-0.13</td><td>40:51:33</td><td>-2.56</td></tr><tr><td>CEmr-2180200</td><td>0.66</td><td>48.03</td><td>-6.51</td><td>39:58:55</td><td>-3.43</td></tr><tr><td>CEmr-2603300</td><td>0.66</td><td>47.11</td><td>-8.29</td><td>42:46:31</td><td>-0.64</td></tr><tr><td>CEsr-2575000</td><td>0.66</td><td>54.10</td><td>5.32</td><td>45:21:57</td><td>1.95</td></tr><tr><td>CEsr-2481000</td><td>0.66</td><td>53.80</td><td>4.73</td><td>43:08:02</td><td>-0.28</td></tr><tr><td>CEmr-2631300</td><td>0.66</td><td>48.42</td><td>-5.74</td><td>43:48:56</td><td>0.40</td></tr><tr><td>CEsr-6231000</td><td>0.66</td><td>52.63</td><td>2.46</td><td>41:09:50</td><td>-2.25</td></tr><tr><td>CEsr-7287000</td><td>0.66</td><td>49.62</td><td>-3.41</td><td>40:58:18</td><td>-2.44</td></tr><tr><td>CEmr-2281900</td><td>0.66</td><td>50.52</td><td>-1.66</td><td>43:19:08</td><td>-0.10</td></tr><tr><td>CEmr-2634200</td><td>0.66</td><td>54.07</td><td>5.26</td><td>40:21:17</td><td>-3.06</td></tr><tr><td>CEsr-5565000</td><td>0.66</td><td>44.65</td><td>-13.09</td><td>42:13:41</td><td>-1.19</td></tr><tr><td>CEsr-2441000</td><td>0.66</td><td>53.12</td><td>3.40</td><td>43:09:53</td><td>-0.25</td></tr><tr><td>CEmr-1275600</td><td>0.66</td><td>47.36</td><td>-7.81</td><td>42:07:55</td><td>-1.28</td></tr><tr><td>CEsr-6097000</td><td>0.66</td><td>49.25</td><td>-4.13</td><td>41:37:40</td><td>-1.79</td></tr><tr><td>CEsr-1311000</td><td>0.66</td><td>54.71</td><td>6.51</td><td>45:10:25</td><td>1.76</td></tr><tr><td>CEsr-5811000</td><td>0.66</td><td>54.99</td><td>7.05</td><td>43:05:33</td><td>-0.32</td></tr><tr><td>CEsr-5936000</td><td>0.66</td><td>47.81</td><td>-6.93</td><td>39:59:50</td><td>-3.42</td></tr><tr><td>C17 untreated mock-infected cells</td><td>0.74</td><td>135.02 ± 5.51</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C17 untreated infected cells</td><td>0.74</td><td>46.33 ± 2.22</td><td>N.D</td><td>39:15:38</td><td>N.D</td></tr><tr><td>CEmr-3463500</td><td>0.74</td><td>44.11</td><td>-4.80</td><td>38:54:39</td><td>-2.49</td></tr><tr><td>CEmr-3413000</td><td>0.74</td><td>51.18</td><td>10.48</td><td>44:28:43</td><td>3.08</td></tr><tr><td>CEmr-2872400</td><td>0.74</td><td>46.37</td><td>0.08</td><td>42:59:45</td><td>1.60</td></tr><tr><td>CEmr-3463600</td><td>0.74</td><td>41.01</td><td>-11.47</td><td>45:19:08</td><td>3.92</td></tr><tr><td>CEsr-5733000</td><td>0.74</td><td>49.90</td><td>7.70</td><td>41:01:27</td><td>-0.37</td></tr><tr><td>CEmr-2708700</td><td>0.74</td><td>52.09</td><td>12.43</td><td>42:00:06</td><td>0.60</td></tr><tr><td>CEsr-6280000</td><td>0.74</td><td>55.14</td><td>19.02</td><td>41:27:39</td><td>0.06</td></tr><tr><td>CEmr-3461200</td><td>0.74</td><td>47.82</td><td>3.22</td><td>41:09:37</td><td>-0.24</td></tr><tr><td>CEmr-3462100</td><td>0.74</td><td>50.55</td><td>9.11</td><td>44:04:13</td><td>2.67</td></tr><tr><td>CEmr-3462900</td><td>0.74</td><td>49.61</td><td>7.09</td><td>44:56:39</td><td>3.55</td></tr><tr><td>CEmr-3463700</td><td>0.74</td><td>49.54</td><td>6.93</td><td>43:16:02</td><td>1.87</td></tr><tr><td>CEsr-6254000</td><td>0.74</td><td>48.74</td><td>5.21</td><td>42:09:47</td><td>0.76</td></tr><tr><td>CEsr-6939000</td><td>0.74</td><td>50.20</td><td>8.35</td><td>43:12:07</td><td>1.80</td></tr><tr><td>CEmr-2579100</td><td>0.74</td><td>44.29</td><td>-4.40</td><td>38:33:34</td><td>-2.84</td></tr><tr><td>CEmr-2572300</td><td>0.74</td><td>49.45</td><td>6.74</td><td>42:26:36</td><td>1.05</td></tr><tr><td>CEmr-2025601</td><td>0.74</td><td>45.99</td><td>-0.73</td><td>41:12:02</td><td>-0.20</td></tr><tr><td>CEmr-2961400</td><td>0.74</td><td>1.38</td><td>-97.02</td><td>0:59:43</td><td>-40.40</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEmr-2964100</td><td>0.74</td><td>56.09</td><td>21.07</td><td>52:02:44</td><td>10.65</td></tr><tr><td>CEmr-2742300</td><td>0.74</td><td>54.52</td><td>17.69</td><td>43:27:09</td><td>2.05</td></tr><tr><td>CEmr-2792300</td><td>0.74</td><td>53.77</td><td>16.06</td><td>42:49:53</td><td>1.43</td></tr><tr><td>CEmr-2391000</td><td>0.74</td><td>53.37</td><td>15.20</td><td>42:28:28</td><td>1.08</td></tr><tr><td>CEmr-2634600</td><td>0.74</td><td>51.00</td><td>10.09</td><td>42:07:28</td><td>0.73</td></tr><tr><td>CEmr-2968500</td><td>0.74</td><td>54.70</td><td>18.06</td><td>44:20:45</td><td>2.95</td></tr><tr><td>CEmr-2962200</td><td>0.74</td><td>48.85</td><td>5.44</td><td>48:06:52</td><td>6.72</td></tr><tr><td>CEmr-3074100</td><td>0.74</td><td>53.37</td><td>15.20</td><td>44:35:27</td><td>3.19</td></tr><tr><td>CEsr-2760000</td><td>0.74</td><td>55.41</td><td>19.61</td><td>42:10:15</td><td>0.77</td></tr><tr><td>CEsr-6434000</td><td>0.74</td><td>51.35</td><td>10.83</td><td>43:43:47</td><td>2.33</td></tr><tr><td>CEmr-2969900</td><td>0.74</td><td>50.40</td><td>8.78</td><td>41:13:23</td><td>-0.18</td></tr><tr><td>CEmr-3068100</td><td>0.74</td><td>65.55</td><td>41.50</td><td>50:31:06</td><td>9.12</td></tr><tr><td>CEmr-2690100</td><td>0.74</td><td>46.09</td><td>-0.51</td><td>41:46:48</td><td>0.38</td></tr><tr><td>CEsr-6470000</td><td>0.74</td><td>54.25</td><td>17.09</td><td>44:04:25</td><td>2.68</td></tr><tr><td>CEsr-6863000</td><td>0.74</td><td>56.28</td><td>21.47</td><td>44:55:09</td><td>3.52</td></tr><tr><td>CEmr-3101700</td><td>0.74</td><td>56.03</td><td>20.94</td><td>46:44:10</td><td>5.34</td></tr><tr><td>CEmr-2430500</td><td>0.74</td><td>52.03</td><td>12.31</td><td>42:22:20</td><td>0.97</td></tr><tr><td>CEsr-5312000</td><td>0.74</td><td>48.19</td><td>4.01</td><td>40:53:50</td><td>-0.50</td></tr><tr><td>CEsr-5412000</td><td>0.74</td><td>45.42</td><td>-1.95</td><td>37:00:50</td><td>-4.38</td></tr><tr><td>CEmr-1723400</td><td>0.74</td><td>56.62</td><td>22.22</td><td>44:15:55</td><td>2.87</td></tr><tr><td>CEmr-6678000</td><td>0.74</td><td>57.24</td><td>23.56</td><td>44:12:26</td><td>2.81</td></tr><tr><td>CEmr-2668700</td><td>0.74</td><td>47.54</td><td>2.62</td><td>40:42:08</td><td>-0.70</td></tr><tr><td>CEsr-3204000</td><td>0.74</td><td>42.54</td><td>-8.19</td><td>38:13:20</td><td>-3.18</td></tr><tr><td>CEsr-7463000</td><td>0.74</td><td>45.42</td><td>-1.97</td><td>39:03:31</td><td>-2.34</td></tr><tr><td>CEsr-6100000</td><td>0.74</td><td>27.21</td><td>-41.28</td><td>25:11:03</td><td>-16.21</td></tr><tr><td>CEmr-2886900</td><td>0.74</td><td>48.87</td><td>5.47</td><td>41:52:07</td><td>0.47</td></tr><tr><td>CEsr-6650000</td><td>0.74</td><td>42.86</td><td>-7.48</td><td>38:22:38</td><td>-3.02</td></tr><tr><td>CEmr-2810000</td><td>0.74</td><td>46.30</td><td>-0.06</td><td>41:01:11</td><td>-0.38</td></tr><tr><td>CEsr-3215000</td><td>0.74</td><td>53.04</td><td>14.48</td><td>43:00:54</td><td>1.62</td></tr><tr><td>CEmr-1671900</td><td>0.74</td><td>39.93</td><td>-13.80</td><td>38:58:05</td><td>-2.43</td></tr><tr><td>CEsr-5310000</td><td>0.74</td><td>48.29</td><td>4.23</td><td>41:23:41</td><td>0.00</td></tr><tr><td>CEmr-1215300</td><td>0.74</td><td>56.95</td><td>22.92</td><td>43:09:41</td><td>1.76</td></tr><tr><td>CEsr-4224000</td><td>0.74</td><td>51.86</td><td>11.94</td><td>42:32:05</td><td>1.14</td></tr><tr><td>CEsr-5610000</td><td>0.74</td><td>51.74</td><td>11.67</td><td>42:29:05</td><td>1.09</td></tr><tr><td>CEmr-2146600</td><td>0.74</td><td>65.36</td><td>41.08</td><td>52:18:01</td><td>10.90</td></tr><tr><td>CEsr-2970000</td><td>0.74</td><td>55.60</td><td>20.02</td><td>44:54:55</td><td>3.52</td></tr><tr><td>CEmr-3053400</td><td>0.74</td><td>52.13</td><td>12.52</td><td>44:00:48</td><td>2.62</td></tr><tr><td>CEsr-1199000</td><td>0.74</td><td>50.32</td><td>8.61</td><td>45:23:38</td><td>4.00</td></tr><tr><td>CEmr-3017000</td><td>0.74</td><td>52.25</td><td>12.79</td><td>45:05:40</td><td>3.70</td></tr><tr><td>CEsr-6980000</td><td>0.74</td><td>48.84</td><td>5.42</td><td>43:40:13</td><td>2.27</td></tr><tr><td>CEmr-3227900</td><td>0.74</td><td>46.21</td><td>-0.26</td><td>41:27:23</td><td>0.06</td></tr><tr><td>CEsr-7047000</td><td>0.74</td><td>42.48</td><td>-8.30</td><td>39:40:51</td><td>-1.72</td></tr><tr><td>CEsr-7076000</td><td>0.74</td><td>53.05</td><td>14.51</td><td>40:29:04</td><td>-0.91</td></tr><tr><td>CEmr-3098100</td><td>0.74</td><td>45.07</td><td>-2.71</td><td>42:02:31</td><td>0.64</td></tr><tr><td>CEmr-3015800</td><td>0.74</td><td>52.11</td><td>12.48</td><td>43:08:32</td><td>1.74</td></tr><tr><td>CEmr-3014800</td><td>0.74</td><td>50.40</td><td>8.78</td><td>43:24:33</td><td>2.01</td></tr><tr><td>CEmr-1989100</td><td>0.74</td><td>50.59</td><td>9.20</td><td>40:46:06</td><td>-0.63</td></tr><tr><td>CEmr-2361000</td><td>0.74</td><td>57.44</td><td>23.98</td><td>44:11:00</td><td>2.79</td></tr><tr><td>CEsr-6968000</td><td>0.74</td><td>49.75</td><td>7.39</td><td>41:00:03</td><td>-0.40</td></tr><tr><td>CEsr-5823000</td><td>0.74</td><td>57.02</td><td>23.07</td><td>43:28:23</td><td>2.07</td></tr><tr><td>CEmr-8242000</td><td>0.74</td><td>50.90</td><td>9.86</td><td>40:39:53</td><td>-0.73</td></tr><tr><td>CEmr-2022800</td><td>0.74</td><td>44.11</td><td>-4.78</td><td>39:52:34</td><td>-1.52</td></tr><tr><td>CEmr-2503900</td><td>0.74</td><td>48.20</td><td>4.04</td><td>40:30:49</td><td>-0.88</td></tr><tr><td>CEsr-2166000</td><td>0.74</td><td>46.74</td><td>0.89</td><td>42:57:21</td><td>1.56</td></tr><tr><td>CEsr5868000</td><td>0.74</td><td>49.32</td><td>6.45</td><td>41:27:13</td><td>0.06</td></tr><tr><td>CEmr-2362900</td><td>0.74</td><td>49.50</td><td>6.83</td><td>40:13:27</td><td>-1.17</td></tr><tr><td>CEsr-2471000</td><td>0.74</td><td>49.47</td><td>6.78</td><td>39:50:05</td><td>-1.56</td></tr><tr><td>CEsr-5810000</td><td>0.74</td><td>46.48</td><td>0.32</td><td>41:35:02</td><td>0.19</td></tr><tr><td>CEsr-4681000</td><td>0.74</td><td>51.46</td><td>11.07</td><td>42:41:04</td><td>1.29</td></tr><tr><td>CEsr-5159000</td><td>0.74</td><td>50.81</td><td>9.66</td><td>41:35:32</td><td>0.19</td></tr><tr><td>CEmr-2500900</td><td>0.74</td><td>43.14</td><td>-6.88</td><td>40:31:31</td><td>-0.87</td></tr></tbody></table>

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<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEsr-2986000</td><td>0.74</td><td>45.13</td><td>-2.59</td><td>41:15:34</td><td>-0.14</td></tr><tr><td>CEsr-2792600</td><td>0.74</td><td>48.88</td><td>5.50</td><td>40:48:22</td><td>-0.59</td></tr><tr><td>C18 untreated mock-infected cells</td><td>0.52</td><td>144.70 ± 11.46</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C18 untreated infected cells</td><td>0.52</td><td>54.02 ± 2.92</td><td>N.D</td><td>43:17:18</td><td>N.D</td></tr><tr><td>CEsr-2390700</td><td>0.52</td><td>51.60</td><td>-4.48</td><td>44:57:54</td><td>-0.73</td></tr><tr><td>CEsr-7201000</td><td>0.52</td><td>54.09</td><td>0.13</td><td>43:33:54</td><td>-2.13</td></tr><tr><td>CEsr-2699500</td><td>0.52</td><td>50.89</td><td>-5.78</td><td>50:09:04</td><td>4.45</td></tr><tr><td>CEsr-4757000</td><td>0.52</td><td>54.06</td><td>0.08</td><td>45:51:13</td><td>0.16</td></tr><tr><td>CEsr-7202000</td><td>0.52</td><td>54.11</td><td>0.17</td><td>46:22:47</td><td>0.68</td></tr><tr><td>CEsr-3000200</td><td>0.52</td><td>51.05</td><td>-5.50</td><td>45:05:42</td><td>-0.60</td></tr><tr><td>CEsr-3053000</td><td>0.52</td><td>49.56</td><td>-8.25</td><td>43:04:57</td><td>-2.62</td></tr><tr><td>CEsr-2435800</td><td>0.52</td><td>59.14</td><td>9.48</td><td>52:35:09</td><td>6.89</td></tr><tr><td>CEsr-1561000</td><td>0.52</td><td>55.42</td><td>2.60</td><td>45:15:22</td><td>-0.44</td></tr><tr><td>CEsr-7294000</td><td>0.52</td><td>61.06</td><td>13.04</td><td>48:50:21</td><td>3.14</td></tr><tr><td>CEsr-2962500</td><td>0.52</td><td>44.72</td><td>-17.22</td><td>46:31:58</td><td>0.83</td></tr><tr><td>CEsr-7235000</td><td>0.52</td><td>51.42</td><td>-4.81</td><td>44:44:32</td><td>-0.96</td></tr><tr><td>CEsr-3053700</td><td>0.52</td><td>53.18</td><td>-1.56</td><td>46:10:32</td><td>0.48</td></tr><tr><td>CEsr-7228000</td><td>0.52</td><td>29.52</td><td>-45.36</td><td>22:31:44</td><td>-23.17</td></tr><tr><td>CEsr-7223000</td><td>0.52</td><td>26.26</td><td>-51.39</td><td>21:46:11</td><td>-23.93</td></tr><tr><td>CEsr-7289000</td><td>0.52</td><td>50.90</td><td>-5.78</td><td>45:24:24</td><td>-0.29</td></tr><tr><td>CEsr-2980700</td><td>0.52</td><td>54.43</td><td>0.77</td><td>43:53:04</td><td>-1.81</td></tr><tr><td>CEsr-7238000</td><td>0.52</td><td>57.08</td><td>5.67</td><td>43:06:02</td><td>-2.60</td></tr><tr><td>CEsr-7214000</td><td>0.52</td><td>37.74</td><td>-30.13</td><td>50:33:16</td><td>4.86</td></tr><tr><td>CEsr-2015000</td><td>0.52</td><td>52.99</td><td>-1.91</td><td>42:44:42</td><td>-2.95</td></tr><tr><td>CEsr-2980100</td><td>0.52</td><td>51.84</td><td>-4.04</td><td>45:20:56</td><td>-0.35</td></tr><tr><td>CEsr-2533600</td><td>0.52</td><td>53.76</td><td>-0.48</td><td>45:41:06</td><td>-0.01</td></tr><tr><td>CEsr-4739000</td><td>0.52</td><td>58.78</td><td>8.82</td><td>46:08:40</td><td>0.45</td></tr><tr><td>CEsr-4770000</td><td>0.52</td><td>51.08</td><td>-5.44</td><td>43:27:41</td><td>-2.24</td></tr><tr><td>CEsr-4733000</td><td>0.52</td><td>55.97</td><td>3.61</td><td>44:04:33</td><td>-1.62</td></tr><tr><td>CEsr-4654000</td><td>0.52</td><td>52.19</td><td>-3.39</td><td>42:51:32</td><td>-2.84</td></tr><tr><td>CEsr-1997500</td><td>0.52</td><td>52.76</td><td>-2.34</td><td>43:09:57</td><td>-2.53</td></tr><tr><td>CEsr-4769000</td><td>0.52</td><td>54.98</td><td>1.78</td><td>44:22:38</td><td>-1.32</td></tr><tr><td>CEsr-2340700</td><td>0.52</td><td>49.15</td><td>-9.01</td><td>44:42:24</td><td>-0.99</td></tr><tr><td>CEsr-4628000</td><td>0.52</td><td>56.35</td><td>4.32</td><td>46:19:58</td><td>0.63</td></tr><tr><td>CEsr-1155000</td><td>0.52</td><td>49.06</td><td>-9.18</td><td>42:50:52</td><td>-2.85</td></tr><tr><td>CEsr-2105500</td><td>0.52</td><td>61.71</td><td>14.23</td><td>50:12:36</td><td>4.51</td></tr><tr><td>CEsr-2870900</td><td>0.52</td><td>54.00</td><td>-0.03</td><td>55:44:04</td><td>10.04</td></tr><tr><td>CEsr-1295000</td><td>0.52</td><td>55.39</td><td>2.54</td><td>45:19:14</td><td>-0.38</td></tr><tr><td>CEsr-1545600</td><td>0.52</td><td>54.91</td><td>1.65</td><td>46:44:04</td><td>1.04</td></tr><tr><td>CEsr-1061000</td><td>0.52</td><td>58.46</td><td>8.22</td><td>46:36:18</td><td>0.91</td></tr><tr><td>CEsr-2697500</td><td>0.52</td><td>49.93</td><td>-7.57</td><td>42:36:27</td><td>-3.09</td></tr><tr><td>CEsr-6040000</td><td>0.52</td><td>59.81</td><td>10.72</td><td>49:01:05</td><td>3.32</td></tr><tr><td>CEsr-1171000</td><td>0.52</td><td>55.40</td><td>2.56</td><td>42:59:20</td><td>-2.71</td></tr><tr><td>CEsr-7549000</td><td>0.52</td><td>50.05</td><td>-7.34</td><td>44:22:49</td><td>-1.32</td></tr><tr><td>CEsr-1031000</td><td>0.52</td><td>54.79</td><td>1.43</td><td>42:59:57</td><td>-2.70</td></tr><tr><td>CEsr-1145000</td><td>0.52</td><td>56.60</td><td>4.77</td><td>46:49:06</td><td>1.12</td></tr><tr><td>CEsr-1621300</td><td>0.52</td><td>55.99</td><td>3.65</td><td>46:40:36</td><td>0.98</td></tr><tr><td>CEsr-7066000</td><td>0.52</td><td>57.10</td><td>5.71</td><td>47:16:45</td><td>1.58</td></tr><tr><td>CEsr-7152000</td><td>0.52</td><td>54.72</td><td>1.30</td><td>44:03:51</td><td>-1.63</td></tr><tr><td>CEsr-7127000</td><td>0.52</td><td>56.95</td><td>5.43</td><td>43:30:22</td><td>-2.19</td></tr><tr><td>CEsr-6317000</td><td>0.52</td><td>46.39</td><td>-14.12</td><td>44:13:45</td><td>-1.47</td></tr><tr><td>CEsr-2581000</td><td>0.52</td><td>50.48</td><td>-6.55</td><td>45:53:13</td><td>0.19</td></tr><tr><td>CEsr-2586000</td><td>0.52</td><td>51.63</td><td>-4.42</td><td>43:55:43</td><td>-1.77</td></tr><tr><td>CEsr-6390000</td><td>0.52</td><td>55.96</td><td>3.59</td><td>45:38:59</td><td>-0.05</td></tr><tr><td>CEsr-6969000</td><td>0.52</td><td>56.66</td><td>4.88</td><td>45:35:13</td><td>-0.11</td></tr><tr><td>CEsr-2733800</td><td>0.52</td><td>61.10</td><td>13.11</td><td>47:56:02</td><td>2.24</td></tr><tr><td>CEsr-2527000</td><td>0.52</td><td>57.04</td><td>5.60</td><td>46:00:56</td><td>0.32</td></tr><tr><td>CEsr-6320000</td><td>0.52</td><td>56.51</td><td>4.62</td><td>46:55:44</td><td>1.23</td></tr><tr><td>CEsr-7128000</td><td>0.52</td><td>42.14</td><td>-21.99</td><td>54:45:12</td><td>9.06</td></tr><tr><td>CEsr-3746000</td><td>0.52</td><td>54.00</td><td>-0.04</td><td>46:04:55</td><td>0.38</td></tr><tr><td>CEsr-2568000</td><td>0.52</td><td>1.85</td><td>25.00</td><td>-1.70368691</td><td>-1.31</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z<sup>-</sup>-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CESr-5085000</td><td>0.52</td><td>44.37</td><td>-17.86</td><td>44:08:10</td><td>-1.56</td></tr><tr><td>CESr-6387000</td><td>0.52</td><td>48.02</td><td>-11.10</td><td>42:18:53</td><td>-3.38</td></tr><tr><td>CEmr-2331600</td><td>0.52</td><td>54.74</td><td>1.33</td><td>45:00:51</td><td>-0.68</td></tr><tr><td>CEmr-1945600</td><td>0.52</td><td>54.97</td><td>1.77</td><td>44:36:40</td><td>-1.09</td></tr><tr><td>CEmr-2293500</td><td>0.52</td><td>51.69</td><td>-4.31</td><td>42:48:07</td><td>-2.90</td></tr><tr><td>CESr-6693000</td><td>0.52</td><td>59.83</td><td>10.75</td><td>48:38:30</td><td>2.94</td></tr><tr><td>CEmr-1675800</td><td>0.52</td><td>56.81</td><td>5.18</td><td>46:29:20</td><td>0.79</td></tr><tr><td>CEmr-2331700</td><td>0.52</td><td>58.64</td><td>8.56</td><td>44:56:00</td><td>-0.76</td></tr><tr><td>CEmr-1208500</td><td>0.52</td><td>56.80</td><td>5.14</td><td>44:57:51</td><td>-0.73</td></tr><tr><td>CESr-2226000</td><td>0.52</td><td>55.39</td><td>2.54</td><td>44:26:46</td><td>-1.25</td></tr><tr><td>CEmr-1329200</td><td>0.52</td><td>59.44</td><td>10.05</td><td>45:31:05</td><td>-0.18</td></tr><tr><td>CESr-6686000</td><td>0.52</td><td>57.56</td><td>6.56</td><td>43:03:08</td><td>-2.65</td></tr><tr><td>CEmr-2105300</td><td>0.52</td><td>56.66</td><td>4.89</td><td>48:09:11</td><td>2.45</td></tr><tr><td>CESr-4218000</td><td>0.52</td><td>54.56</td><td>1.00</td><td>47:39:45</td><td>1.96</td></tr><tr><td>CESr-3787000</td><td>0.52</td><td>54.21</td><td>0.35</td><td>42:31:57</td><td>-3.17</td></tr><tr><td>CESr-6688000</td><td>0.52</td><td>60.95</td><td>12.83</td><td>46:07:03</td><td>0.42</td></tr><tr><td>CEmr-2103500</td><td>0.52</td><td>46.82</td><td>-13.33</td><td>42:08:21</td><td>-3.56</td></tr><tr><td>CEmr-2330600</td><td>0.52</td><td>53.51</td><td>-0.93</td><td>43:30:09</td><td>-2.20</td></tr><tr><td>CEmr-1546000</td><td>0.52</td><td>49.77</td><td>-7.87</td><td>42:28:02</td><td>-3.23</td></tr><tr><td>CESr-5018000</td><td>0.52</td><td>52.39</td><td>-3.01</td><td>46:13:51</td><td>0.53</td></tr><tr><td>CEmr-1949600</td><td>0.52</td><td>51.49</td><td>-4.68</td><td>44:51:11</td><td>-0.85</td></tr><tr><td>CESr-2601000</td><td>0.52</td><td>57.87</td><td>7.12</td><td>45:12:59</td><td>-0.48</td></tr><tr><td>C19 untreated mock-infected cells</td><td>0.67</td><td>127.33 ± 8.37</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C19 untreated infected cells</td><td>0.67</td><td>41.72 ± 0.95</td><td>N.D</td><td>33:53:05</td><td>N.D</td></tr><tr><td>CESr-3029000</td><td>0.67</td><td>37.32</td><td>-10.54</td><td>37:51:19</td><td>1.35</td></tr><tr><td>CESr-3050000</td><td>0.67</td><td>42.50</td><td>1.86</td><td>37:08:27</td><td>0.63</td></tr><tr><td>CESr-5040000</td><td>0.67</td><td>37.46</td><td>-10.22</td><td>38:46:11</td><td>2.26</td></tr><tr><td>CESr-2291000</td><td>0.67</td><td>38.71</td><td>-7.22</td><td>33:58:54</td><td>-2.53</td></tr><tr><td>CESr-1599000</td><td>0.67</td><td>44.51</td><td>6.69</td><td>38:11:41</td><td>1.69</td></tr><tr><td>CESr-3093000</td><td>0.67</td><td>42.16</td><td>1.05</td><td>37:10:38</td><td>0.67</td></tr><tr><td>CESr-5111000</td><td>0.67</td><td>41.54</td><td>-0.43</td><td>36:31:18</td><td>0.01</td></tr><tr><td>CESr-1583000</td><td>0.67</td><td>41.11</td><td>-1.47</td><td>36:31:00</td><td>0.01</td></tr><tr><td>CESr-3070000</td><td>0.67</td><td>40.40</td><td>-3.17</td><td>37:10:26</td><td>0.67</td></tr><tr><td>CEmr-3023600</td><td>0.67</td><td>40.27</td><td>-3.47</td><td>36:28:16</td><td>-0.04</td></tr><tr><td>CESr-5112000</td><td>0.67</td><td>40.71</td><td>-2.43</td><td>37:46:13</td><td>1.26</td></tr><tr><td>CESr-5845000</td><td>0.67</td><td>46.93</td><td>12.48</td><td>42:25:46</td><td>5.92</td></tr><tr><td>CESr-5619000</td><td>0.67</td><td>40.78</td><td>-2.26</td><td>36:05:21</td><td>-0.42</td></tr><tr><td>CEpa-18</td><td>0.67</td><td>40.61</td><td>-2.67</td><td>36:22:06</td><td>-0.14</td></tr><tr><td>CESr-1073000</td><td>0.67</td><td>38.15</td><td>-8.56</td><td>33:53:01</td><td>-2.62</td></tr><tr><td>CESr-5171000</td><td>0.67</td><td>34.39</td><td>-17.57</td><td>34:29:21</td><td>-2.02</td></tr><tr><td>CEmr-2532200</td><td>0.67</td><td>46.39</td><td>11.18</td><td>39:35:59</td><td>3.09</td></tr><tr><td>CESr-1586000</td><td>0.67</td><td>42.25</td><td>1.26</td><td>36:46:43</td><td>0.27</td></tr><tr><td>CESr-1024000</td><td>0.67</td><td>44.16</td><td>5.83</td><td>39:05:38</td><td>2.59</td></tr><tr><td>CESr-1240000</td><td>0.67</td><td>45.42</td><td>8.86</td><td>38:26:59</td><td>1.94</td></tr><tr><td>CEmr-2506700</td><td>0.67</td><td>41.34</td><td>-0.92</td><td>42:09:41</td><td>5.65</td></tr><tr><td>CESr-1074000</td><td>0.67</td><td>44.16</td><td>5.84</td><td>37:14:24</td><td>0.73</td></tr><tr><td>CESr-7126000</td><td>0.67</td><td>39.11</td><td>-6.26</td><td>33:53:49</td><td>-2.61</td></tr><tr><td>CEmr-2505900</td><td>0.67</td><td>40.86</td><td>-2.06</td><td>36:00:37</td><td>-0.50</td></tr><tr><td>CESr-1250000</td><td>0.67</td><td>42.63</td><td>2.18</td><td>37:05:17</td><td>0.58</td></tr><tr><td>CESr-4979000</td><td>0.67</td><td>40.50</td><td>-2.92</td><td>35:26:57</td><td>-1.06</td></tr><tr><td>CEmr-2434900</td><td>0.67</td><td>46.21</td><td>10.74</td><td>40:51:54</td><td>4.36</td></tr><tr><td>CEmr-2871700</td><td>0.67</td><td>33.15</td><td>-20.55</td><td>19:30:47</td><td>-16.99</td></tr><tr><td>CESr-7199000</td><td>0.67</td><td>35.55</td><td>-14.79</td><td>38:32:28</td><td>2.03</td></tr><tr><td>CESr-6579000</td><td>0.67</td><td>45.93</td><td>10.08</td><td>38:35:41</td><td>2.09</td></tr><tr><td>CESr-2991000</td><td>0.67</td><td>40.18</td><td>-3.69</td><td>36:10:59</td><td>-0.32</td></tr><tr><td>CESr-2348000</td><td>0.67</td><td>37.09</td><td>-11.09</td><td>32:30:34</td><td>-4.00</td></tr><tr><td>CESr-3041000</td><td>0.67</td><td>44.47</td><td>6.59</td><td>37:23:17</td><td>0.88</td></tr><tr><td>CESr-3069000</td><td>0.67</td><td>41.71</td><td>-0.03</td><td>35:28:10</td><td>-1.04</td></tr><tr><td>CESr-4983000</td><td>0.67</td><td>38.52</td><td>-7.69</td><td>35:49:09</td><td>-0.69</td></tr><tr><td>CESr-5110000</td><td>0.67</td><td>39.64</td><td>-5.00</td><td>34:22:30</td><td>-2.13</td></tr><tr><td>CESr-3083000</td><td>0.67</td><td>30.59</td><td>-26.68</td><td>35:50:41</td><td>-0.66</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEmr-2364300</td><td>0.67</td><td>39.77</td><td>-4.69</td><td>35:17:23</td><td>-1.22</td></tr><tr><td>CEsr-1225000</td><td>0.67</td><td>43.28</td><td>3.72</td><td>37:25:59</td><td>0.93</td></tr><tr><td>CEsr-4909000</td><td>0.67</td><td>34.89</td><td>-16.38</td><td>36:26:55</td><td>-0.06</td></tr><tr><td>CEsr-6505000</td><td>0.67</td><td>43.46</td><td>4.17</td><td>39:25:17</td><td>2.91</td></tr><tr><td>CEsr-3705000</td><td>0.67</td><td>35.26</td><td>-15.50</td><td>40:04:12</td><td>3.56</td></tr><tr><td>CEsr-3741000</td><td>0.67</td><td>42.73</td><td>2.40</td><td>36:59:50</td><td>0.49</td></tr><tr><td>CEmr-2577800</td><td>0.67</td><td>42.39</td><td>1.61</td><td>40:18:49</td><td>3.81</td></tr><tr><td>CEmr-2491200</td><td>0.67</td><td>35.22</td><td>-15.60</td><td>35:48:44</td><td>-0.69</td></tr><tr><td>CEsr-3717000</td><td>0.67</td><td>42.52</td><td>1.90</td><td>35:31:56</td><td>-0.97</td></tr><tr><td>CEsr-6249000</td><td>0.67</td><td>40.53</td><td>-2.86</td><td>35:50:39</td><td>-0.66</td></tr><tr><td>CEsr-3751000</td><td>0.67</td><td>42.15</td><td>1.02</td><td>36:05:23</td><td>-0.42</td></tr><tr><td>CEsr-2578900</td><td>0.67</td><td>40.05</td><td>-4.00</td><td>37:25:39</td><td>0.92</td></tr><tr><td>CEsr-3443000</td><td>0.67</td><td>42.15</td><td>1.02</td><td>35:51:22</td><td>-0.65</td></tr><tr><td>CEsr-2578100</td><td>0.67</td><td>37.63</td><td>-9.81</td><td>36:50:03</td><td>0.33</td></tr><tr><td>CEsr-3721000</td><td>0.67</td><td>42.65</td><td>2.23</td><td>38:44:57</td><td>2.24</td></tr><tr><td>CEsr-3446000</td><td>0.67</td><td>43.51</td><td>4.28</td><td>36:04:30</td><td>-0.43</td></tr><tr><td>CEmr-1622900</td><td>0.67</td><td>39.31</td><td>-5.80</td><td>34:38:16</td><td>-1.87</td></tr><tr><td>CEsr-3494000</td><td>0.67</td><td>40.59</td><td>-2.70</td><td>36:38:33</td><td>0.14</td></tr><tr><td>CEsr-3762000</td><td>0.67</td><td>42.35</td><td>1.51</td><td>36:29:50</td><td>-0.01</td></tr><tr><td>CEsr-1611000</td><td>0.67</td><td>39.87</td><td>-4.44</td><td>38:38:27</td><td>2.13</td></tr><tr><td>CEsr-3461000</td><td>0.67</td><td>41.37</td><td>-0.85</td><td>35:41:45</td><td>-0.81</td></tr><tr><td>CEsr-5122000</td><td>0.67</td><td>40.21</td><td>-3.62</td><td>39:06:12</td><td>2.60</td></tr><tr><td>CEsr-6276000</td><td>0.67</td><td>40.76</td><td>-2.30</td><td>36:28:46</td><td>-0.03</td></tr><tr><td>CEsr-3493000</td><td>0.67</td><td>40.95</td><td>-1.84</td><td>35:47:28</td><td>-0.72</td></tr><tr><td>CEsr-6443000</td><td>0.67</td><td>30.13</td><td>-27.78</td><td>36:18:30</td><td>-0.20</td></tr><tr><td>CEsr-5652000</td><td>0.67</td><td>42.03</td><td>0.73</td><td>37:04:51</td><td>0.57</td></tr><tr><td>CEsr-6126000</td><td>0.67</td><td>38.11</td><td>-8.66</td><td>33:54:32</td><td>-2.60</td></tr><tr><td>CEmr-2557200</td><td>0.67</td><td>40.76</td><td>-2.31</td><td>38:11:17</td><td>1.68</td></tr><tr><td>CEsr-6445000</td><td>0.67</td><td>39.47</td><td>-5.41</td><td>36:06:36</td><td>-0.40</td></tr><tr><td>CEsr-6148000</td><td>0.67</td><td>40.08</td><td>-3.94</td><td>35:58:33</td><td>-0.53</td></tr><tr><td>CEmr-2632800</td><td>0.67</td><td>37.18</td><td>-10.90</td><td>35:59:41</td><td>-0.51</td></tr><tr><td>CEmr-2288100</td><td>0.67</td><td>44.51</td><td>6.69</td><td>36:46:21</td><td>0.27</td></tr><tr><td>CEmr-2740700</td><td>0.67</td><td>40.35</td><td>-3.28</td><td>34:27:46</td><td>-2.04</td></tr><tr><td>CEsr-5673000</td><td>0.67</td><td>37.85</td><td>-9.28</td><td>36:59:08</td><td>0.48</td></tr><tr><td>CEmr-3250900</td><td>0.67</td><td>43.59</td><td>4.47</td><td>38:38:45</td><td>2.14</td></tr><tr><td>CEmr-2741600</td><td>0.67</td><td>41.44</td><td>-0.67</td><td>38:22:36</td><td>1.87</td></tr><tr><td>CEmr-2584500</td><td>0.67</td><td>42.25</td><td>1.27</td><td>36:33:28</td><td>0.05</td></tr><tr><td>CEsr-618400</td><td>0.67</td><td>41.76</td><td>0.09</td><td>43:50:01</td><td>7.33</td></tr><tr><td>CEmr-2742200</td><td>0.67</td><td>38.09</td><td>-8.72</td><td>36:48:00</td><td>0.29</td></tr><tr><td>CEsr-1622000</td><td>0.67</td><td>39.82</td><td>-4.55</td><td>38:21:15</td><td>1.85</td></tr><tr><td>CEsr-4658000</td><td>0.67</td><td>40.29</td><td>-3.43</td><td>39:02:22</td><td>2.53</td></tr><tr><td>CEmr-1401400</td><td>0.67</td><td>40.97</td><td>-1.80</td><td>36:30:04</td><td>-0.01</td></tr><tr><td>CEmr-2435300</td><td>0.67</td><td>40.56</td><td>-2.79</td><td>38:47:23</td><td>2.28</td></tr><tr><td>C20 untreated mock-infected cells</td><td>0.72</td><td>136.01 ± 7.86</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C20 untreated infected cells</td><td>0.72</td><td>41.83 ± 0.79</td><td>N.D</td><td>31:51:58</td><td>N.D</td></tr><tr><td>CEmr-2691200</td><td>0.72</td><td>37.52</td><td>-10.31</td><td>36:20:43</td><td>-0.20</td></tr><tr><td>CEsr-1727100</td><td>0.72</td><td>41.62</td><td>-0.52</td><td>36:44:40</td><td>0.20</td></tr><tr><td>CEmr-1845800</td><td>0.72</td><td>40.41</td><td>-3.39</td><td>36:42:19</td><td>0.16</td></tr><tr><td>CEsr-2264000</td><td>0.72</td><td>41.97</td><td>0.32</td><td>36:16:57</td><td>-0.26</td></tr><tr><td>CEmr-2635500</td><td>0.72</td><td>37.77</td><td>-9.72</td><td>34:49:42</td><td>-1.72</td></tr><tr><td>CEsr-3617000</td><td>0.72</td><td>42.33</td><td>1.19</td><td>37:09:22</td><td>0.61</td></tr><tr><td>CEmr-1847600</td><td>0.72</td><td>42.10</td><td>0.64</td><td>36:32:50</td><td>0.00</td></tr><tr><td>CEsr-3674000</td><td>0.72</td><td>34.32</td><td>-17.97</td><td>41:10:16</td><td>4.62</td></tr><tr><td>CEsr-1947000</td><td>0.72</td><td>38.37</td><td>-8.29</td><td>37:38:37</td><td>1.10</td></tr><tr><td>CEsr-3653000</td><td>0.72</td><td>37.96</td><td>-9.26</td><td>35:58:46</td><td>-0.57</td></tr><tr><td>CEsr-5736000</td><td>0.72</td><td>45.13</td><td>7.87</td><td>39:12:03</td><td>2.65</td></tr><tr><td>CEsr-3677000</td><td>0.72</td><td>42.43</td><td>1.42</td><td>37:13:04</td><td>0.67</td></tr><tr><td>CEsr-3650000</td><td>0.72</td><td>36.90</td><td>-11.79</td><td>35:08:27</td><td>-1.41</td></tr><tr><td>CEmr-2987200</td><td>0.72</td><td>37.83</td><td>-9.57</td><td>36:31:32</td><td>-0.02</td></tr><tr><td>CEmr-2401400</td><td>0.72</td><td>39.80</td><td>-4.87</td><td>35:42:09</td><td>-0.84</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CESr-3693000</td><td>0.72</td><td>41.20</td><td>-1.52</td><td>37:08:34</td><td>0.60</td></tr><tr><td>CEmr-3040700</td><td>0.72</td><td>38.52</td><td>-7.92</td><td>36:24:26</td><td>-0.14</td></tr><tr><td>CESr-7418000</td><td>0.72</td><td>32.99</td><td>-21.14</td><td>40:10:59</td><td>3.64</td></tr><tr><td>CEmr-3392800</td><td>0.72</td><td>40.98</td><td>-2.04</td><td>36:19:48</td><td>-0.22</td></tr><tr><td>CEmr-1479000</td><td>0.72</td><td>40.03</td><td>-4.30</td><td>35:42:13</td><td>-0.84</td></tr><tr><td>CEmr-2504900</td><td>0.72</td><td>42.31</td><td>1.15</td><td>37:17:48</td><td>0.75</td></tr><tr><td>CEmr-3395500</td><td>0.72</td><td>36.36</td><td>-13.09</td><td>34:12:50</td><td>-2.33</td></tr><tr><td>CEmr-1440900</td><td>0.72</td><td>37.72</td><td>-9.84</td><td>34:10:05</td><td>-2.38</td></tr><tr><td>CESr-7023000</td><td>0.72</td><td>37.59</td><td>-10.13</td><td>33:38:15</td><td>-2.91</td></tr><tr><td>CESr-6449000</td><td>0.72</td><td>42.24</td><td>0.97</td><td>37:57:48</td><td>1.42</td></tr><tr><td>CESr-5118000</td><td>0.72</td><td>40.54</td><td>-3.10</td><td>36:24:59</td><td>-0.13</td></tr><tr><td>CEmr-2285600</td><td>0.72</td><td>42.24</td><td>0.98</td><td>37:09:11</td><td>0.61</td></tr><tr><td>CESr-6751000</td><td>0.72</td><td>41.68</td><td>-0.36</td><td>35:38:27</td><td>-0.91</td></tr><tr><td>CEmr-3097600</td><td>0.72</td><td>38.86</td><td>-7.11</td><td>36:12:54</td><td>-0.33</td></tr><tr><td>CESr-6946000</td><td>0.72</td><td>36.72</td><td>-12.22</td><td>32:10:56</td><td>-4.36</td></tr><tr><td>CESr-6596000</td><td>0.72</td><td>36.59</td><td>-12.53</td><td>33:06:01</td><td>-3.45</td></tr><tr><td>CEmr-2328600</td><td>0.72</td><td>48.31</td><td>15.48</td><td>38:16:13</td><td>1.72</td></tr><tr><td>CEmr-1634400</td><td>0.72</td><td>38.17</td><td>-8.77</td><td>35:00:45</td><td>-1.53</td></tr><tr><td>CESr-6096000</td><td>0.72</td><td>42.05</td><td>0.53</td><td>35:58:15</td><td>-0.58</td></tr><tr><td>CEmr-1844400</td><td>0.72</td><td>40.23</td><td>-3.83</td><td>37:29:24</td><td>0.94</td></tr><tr><td>CESr-3579000</td><td>0.72</td><td>39.50</td><td>-5.58</td><td>37:12:26</td><td>0.66</td></tr><tr><td>CEmr-2431900</td><td>0.72</td><td>45.38</td><td>8.48</td><td>39:50:28</td><td>3.29</td></tr><tr><td>CEmr-2433900</td><td>0.72</td><td>42.23</td><td>0.94</td><td>37:30:04</td><td>0.95</td></tr><tr><td>CEmr-2430600</td><td>0.72</td><td>42.58</td><td>1.78</td><td>37:00:34</td><td>0.46</td></tr><tr><td>CEmr-2435000</td><td>0.72</td><td>46.81</td><td>11.89</td><td>36:47:06</td><td>0.24</td></tr><tr><td>CESr-6165000</td><td>0.72</td><td>37.61</td><td>-10.09</td><td>34:24:59</td><td>-2.13</td></tr><tr><td>CEmr-1762300</td><td>0.72</td><td>38.28</td><td>-8.50</td><td>36:34:59</td><td>0.04</td></tr><tr><td>CEmr-2435600</td><td>0.72</td><td>47.40</td><td>13.31</td><td>44:35:24</td><td>8.04</td></tr><tr><td>CESr-7016000</td><td>0.72</td><td>37.09</td><td>-11.35</td><td>36:44:53</td><td>0.20</td></tr><tr><td>CEmr-3203200</td><td>0.72</td><td>38.01</td><td>-9.13</td><td>34:18:05</td><td>-2.25</td></tr><tr><td>CESr-1787000</td><td>0.72</td><td>39.79</td><td>-4.87</td><td>35:42:02</td><td>-0.85</td></tr><tr><td>CESr-4751000</td><td>0.72</td><td>38.23</td><td>-8.62</td><td>37:40:23</td><td>1.13</td></tr><tr><td>CESr-4752000</td><td>0.72</td><td>39.55</td><td>-5.46</td><td>34:36:57</td><td>-1.93</td></tr><tr><td>CESr-2877000</td><td>0.72</td><td>37.47</td><td>-10.43</td><td>35:16:48</td><td>-1.27</td></tr><tr><td>CESr-2128000</td><td>0.72</td><td>43.38</td><td>3.69</td><td>35:35:47</td><td>-0.95</td></tr><tr><td>CESr-4761000</td><td>0.72</td><td>43.06</td><td>2.94</td><td>35:49:35</td><td>-0.72</td></tr><tr><td>CESr-1946000</td><td>0.72</td><td>45.27</td><td>8.23</td><td>36:38:32</td><td>0.10</td></tr><tr><td>CEmr-1384800</td><td>0.72</td><td>40.05</td><td>-4.27</td><td>35:54:04</td><td>-0.65</td></tr><tr><td>CESr-3427000</td><td>0.72</td><td>43.81</td><td>4.72</td><td>36:24:31</td><td>-0.14</td></tr><tr><td>CESr-1498000</td><td>0.72</td><td>37.58</td><td>-10.16</td><td>33:22:04</td><td>-3.18</td></tr><tr><td>CEmr-1334000</td><td>0.72</td><td>44.83</td><td>7.17</td><td>38:14:04</td><td>1.69</td></tr><tr><td>CESr-2276000</td><td>0.72</td><td>41.54</td><td>-0.71</td><td>38:18:40</td><td>1.76</td></tr><tr><td>CESr-1515000</td><td>0.72</td><td>41.87</td><td>0.09</td><td>37:01:08</td><td>0.47</td></tr><tr><td>CESr-5948000</td><td>0.72</td><td>34.79</td><td>-16.83</td><td>37:48:19</td><td>1.26</td></tr><tr><td>CESr-1527000</td><td>0.72</td><td>41.90</td><td>0.17</td><td>35:30:17</td><td>-1.04</td></tr><tr><td>CESr-5972000</td><td>0.72</td><td>38.95</td><td>-6.88</td><td>35:04:16</td><td>-1.48</td></tr><tr><td>CESr-1547000</td><td>0.72</td><td>41.89</td><td>0.14</td><td>35:45:19</td><td>-0.79</td></tr><tr><td>CESr-5974000</td><td>0.72</td><td>41.66</td><td>-0.41</td><td>36:13:43</td><td>-0.32</td></tr><tr><td>CEmr-1507400</td><td>0.72</td><td>40.23</td><td>-3.82</td><td>34:38:20</td><td>-1.91</td></tr><tr><td>CEmr-1511500</td><td>0.72</td><td>37.20</td><td>-11.08</td><td>34:54:40</td><td>-1.64</td></tr><tr><td>CEmr-2100100</td><td>0.72</td><td>37.21</td><td>-11.05</td><td>35:25:01</td><td>-1.13</td></tr><tr><td>CEmr-3263100</td><td>0.72</td><td>39.93</td><td>-4.54</td><td>36:19:32</td><td>-0.22</td></tr><tr><td>CEmr-1618000</td><td>0.72</td><td>32.62</td><td>-22.02</td><td>35:41:52</td><td>-0.85</td></tr><tr><td>CESr-7428000</td><td>0.72</td><td>39.37</td><td>-5.89</td><td>35:29:14</td><td>-1.06</td></tr><tr><td>CESr-6457000</td><td>0.72</td><td>44.30</td><td>5.90</td><td>36:44:32</td><td>0.20</td></tr><tr><td>CEmr-1506900</td><td>0.72</td><td>40.27</td><td>-3.75</td><td>36:08:35</td><td>-0.40</td></tr><tr><td>CESr-4661000</td><td>0.72</td><td>37.63</td><td>-10.06</td><td>33:08:45</td><td>-3.40</td></tr><tr><td>CEmr-2243900</td><td>0.72</td><td>36.52</td><td>-12.69</td><td>35:32:01</td><td>-1.01</td></tr><tr><td>CESr-2965500</td><td>0.72</td><td>39.27</td><td>-6.12</td><td>35:52:26</td><td>-0.67</td></tr><tr><td>CEmr-1500800</td><td>0.72</td><td>39.20</td><td>-6.30</td><td>39:26:46</td><td>2.90</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEmr-2968600</td><td>0.72</td><td>37.32</td><td>-10.78</td><td>34:55:20</td><td>-1.62</td></tr><tr><td>CEmr-2388200</td><td>0.72</td><td>36.91</td><td>-11.76</td><td>35:24:23</td><td>-1.14</td></tr><tr><td>CEmr-3264000</td><td>0.72</td><td>38.44</td><td>-8.11</td><td>36:17:24</td><td>-0.26</td></tr><tr><td>CEsr-6750000</td><td>0.72</td><td>40.03</td><td>-4.31</td><td>35:53:48</td><td>-0.65</td></tr><tr><td>CEmr-2031800</td><td>0.72</td><td>41.31</td><td>-1.26</td><td>36:07:38</td><td>-0.42</td></tr><tr><td>C21 untreated mock-infected cells</td><td>0.68</td><td>121.79 ± 4.41</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C21 untreated infected cells</td><td>0.68</td><td>40.10 ± 1.60</td><td>N.D</td><td>37:02:50</td><td>N.D</td></tr><tr><td>CEmr-1870900</td><td>0.68</td><td>39.93</td><td>-4.54</td><td>36:36:04</td><td>-1.56</td></tr><tr><td>CEsr-6210000</td><td>0.68</td><td>42.19</td><td>0.86</td><td>37:50:29</td><td>-0.32</td></tr><tr><td>CEsr-6217000</td><td>0.68</td><td>43.69</td><td>4.43</td><td>36:59:24</td><td>-1.17</td></tr><tr><td>CEsr-6237000</td><td>0.68</td><td>38.57</td><td>-7.79</td><td>35:08:36</td><td>-3.02</td></tr><tr><td>CEsr-6238000</td><td>0.68</td><td>41.02</td><td>-1.95</td><td>36:35:35</td><td>-1.57</td></tr><tr><td>CEsr-6265000</td><td>0.68</td><td>42.22</td><td>0.92</td><td>37:29:20</td><td>-0.67</td></tr><tr><td>CEsr-6990000</td><td>0.68</td><td>37.32</td><td>-10.80</td><td>37:39:04</td><td>-0.51</td></tr><tr><td>C22 untreated mock-infected cells</td><td>0.95</td><td>87.80 ± 0.86</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C22 untreated infected cells</td><td>0.95</td><td>37.36 ± 0.39</td><td>N.D</td><td>35:11:02</td><td>N.D</td></tr><tr><td>CEmr-3267300</td><td>0.95</td><td>33.80</td><td>-9.53</td><td>36:19:49</td><td>1.15</td></tr><tr><td>CEmr-3123500</td><td>0.95</td><td>39.85</td><td>6.66</td><td>38:08:15</td><td>2.95</td></tr><tr><td>CEmr-3484600</td><td>0.95</td><td>46.38</td><td>24.12</td><td>43:02:01</td><td>7.85</td></tr><tr><td>CEmr-3540300</td><td>0.95</td><td>36.45</td><td>-2.44</td><td>36:46:18</td><td>1.59</td></tr><tr><td>CEmr-3540900</td><td>0.95</td><td>47.23</td><td>26.41</td><td>42:51:09</td><td>7.67</td></tr><tr><td>CEmr-3541100</td><td>0.95</td><td>36.38</td><td>-2.64</td><td>38:02:07</td><td>2.85</td></tr><tr><td>C23 untreated mock-infected cells</td><td>0.81</td><td>92.16 ± 5.50</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C23 untreated infected cells</td><td>0.81</td><td>41.58 ± 0.30</td><td>N.D</td><td>37:48:19</td><td>N.D</td></tr><tr><td>CEmr-3266100</td><td>0.81</td><td>16.52</td><td>-60.27</td><td>33:49:27</td><td>-3.98</td></tr><tr><td>CEmr-3411000</td><td>0.81</td><td>31.01</td><td>-25.41</td><td>0:27:01</td><td>-37.35</td></tr><tr><td>CEmr-3410400</td><td>0.81</td><td>39.05</td><td>-6.07</td><td>46:16:06</td><td>3.00</td></tr><tr><td>CEmr-3410900</td><td>0.81</td><td>43.20</td><td>3.90</td><td>40:05:19</td><td>2.28</td></tr><tr><td>CEmr-3411100</td><td>0.81</td><td>39.58</td><td>-4.79</td><td>38:51:00</td><td>1.04</td></tr><tr><td>CEsr-1088000</td><td>0.81</td><td>33.97</td><td>-18.29</td><td>37:17:11</td><td>-0.52</td></tr><tr><td>C24 untreated mock-infected cells</td><td>0.94</td><td>111.24 ± 13.06</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C24 untreated infected cells</td><td>0.94</td><td>38.27 ± 1.68</td><td>N.D</td><td>39:38:12</td><td>N.D</td></tr><tr><td>CEmr-1982700</td><td>0.94</td><td>38.68</td><td>1.06</td><td>39:58:22</td><td>0.34</td></tr><tr><td>CEmr-3222500</td><td>0.94</td><td>35.28</td><td>-7.81</td><td>35:31:27</td><td>-4.11</td></tr><tr><td>CEmr-3261900</td><td>0.94</td><td>40.63</td><td>6.15</td><td>42:50:00</td><td>3.20</td></tr><tr><td>CEmr-3262100</td><td>0.94</td><td>46.53</td><td>21.58</td><td>45:07:04</td><td>5.48</td></tr><tr><td>CEmr-3262300</td><td>0.94</td><td>43.05</td><td>12.47</td><td>41:12:22</td><td>1.57</td></tr><tr><td>CEmr-3266400</td><td>0.94</td><td>40.79</td><td>6.56</td><td>42:50:56</td><td>3.21</td></tr><tr><td>C25 untreated mock-infected cells</td><td>0.86</td><td>110.62 ± 2.41</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C25 untreated infected cells</td><td>0.86</td><td>36.83 ± 6.33</td><td>N.D</td><td>39:22:44</td><td>N.D</td></tr><tr><td>CEmr-3266500</td><td>0.86</td><td>40.71</td><td>10.52</td><td>43:33:36</td><td>3.66</td></tr><tr><td>CEmr-3266700</td><td>0.86</td><td>39.42</td><td>7.01</td><td>43:58:16</td><td>4.08</td></tr><tr><td>CEmr-3266800</td><td>0.86</td><td>45.81</td><td>24.36</td><td>43:18:45</td><td>3.42</td></tr><tr><td>CEmr-3267000</td><td>0.86</td><td>41.12</td><td>11.63</td><td>44:01:42</td><td>4.13</td></tr><tr><td>CEmr-3267200</td><td>0.86</td><td>40.48</td><td>9.90</td><td>40:21:36</td><td>0.46</td></tr><tr><td>CEmr-3267600</td><td>0.86</td><td>41.18</td><td>11.79</td><td>46:43:26</td><td>6.83</td></tr><tr><td>C26 untreated mock-infected cells</td><td>0.86</td><td>101.52 ± 2.66</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C26 untreated infected cells</td><td>0.86</td><td>32.59 ± 3.77</td><td>N.D</td><td>38:16:03</td><td>N.D</td></tr><tr><td>CEmr-3267700</td><td>0.86</td><td>40.97</td><td>25.73</td><td>45:23:46</td><td>4.47</td></tr><tr><td>CEmr-3267800</td><td>0.86</td><td>39.55</td><td>21.38</td><td>43:16:26</td><td>-15.94</td></tr><tr><td>CEmr-3267900</td><td>0.86</td><td>53.04</td><td>62.78</td><td>6:24:17</td><td>10.62</td></tr><tr><td>CEmr-3268000</td><td>0.86</td><td>21.56</td><td>-33.83</td><td>18:19:35</td><td>-19.94</td></tr><tr><td>CEmr-3269600</td><td>0.86</td><td>36.81</td><td>12.95</td><td>38:57:13</td><td>0.69</td></tr><tr><td>CEmr-3269800</td><td>0.86</td><td>42.93</td><td>31.75</td><td>43:15:14</td><td>4.99</td></tr><tr><td>C27 untreated mock-infected cells</td><td>0.87</td><td>111.24 ± 13.73</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C27 untreated infected cells</td><td>0.87</td><td>44.12 ± 0.07</td><td>N.D</td><td>40:59:13</td><td>N.D</td></tr><tr><td>CEsr-233100</td><td>0.87</td><td>47.76</td><td>8.25</td><td>40:17:57</td><td>-0.69</td></tr><tr><td>CEsr-1824000</td><td>0.87</td><td>35.98</td><td>-18.44</td><td>37:38:31</td><td>-3.34</td></tr><tr><td>CEsr-1077000</td><td>0.87</td><td>40.70</td><td>-7.74</td><td>44:27:13</td><td>3.47</td></tr><tr><td>CEsr-1075000</td><td>0.87</td><td>45.12</td><td>2.27</td><td>42:52:12</td><td>1.88</td></tr><tr><td>CEmr-3411200</td><td>0.87</td><td>39.45</td><td>-10.59</td><td>43:59:57</td><td>3.01</td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 2 (continued)**</caption><thead><tr><th>Compound name</th><th>Z'-factor</th><th>AUC<sub>n</sub></th><th>%AUC<sub>n</sub></th><th>CIT<sub>50</sub></th><th>ΔCIT<sub>50</sub></th></tr></thead><tbody><tr><td>CEmr-3269900</td><td>0.87</td><td>38.50</td><td>-12.74</td><td>39:17:16</td><td>-1.70</td></tr><tr><td>C28 untreated mock-infected cells</td><td>0.73</td><td>92.91 ± 6.21</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C28 untreated infected cells</td><td>0.73</td><td>37.86 ± 0.36</td><td>N.D</td><td>38:52:58</td><td>N.D</td></tr><tr><td>CEsr-1057000</td><td>0.73</td><td>37.93</td><td>0.15</td><td>37:51:08</td><td>-1.03</td></tr><tr><td>CEmr-3269700</td><td>0.73</td><td>23.47</td><td>-32.63</td><td>17:24:46</td><td>-21.47</td></tr><tr><td>CEmr-3123300</td><td>0.73</td><td>29.65</td><td>-18.62</td><td>33:05:10</td><td>-5.80</td></tr><tr><td>C29 untreated mock-infected cells</td><td>0.98</td><td>94.21 ± 8.18</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C29 untreated infected cells</td><td>0.98</td><td>41.33 ± 4.01</td><td>N.D</td><td>45:42:21</td><td>N.D</td></tr><tr><td>CEmr-3222400</td><td>0.98</td><td>23.47</td><td>-40.48</td><td>29:49:30</td><td>-19.43</td></tr><tr><td>CEmr-3261500</td><td>0.98</td><td>29.65</td><td>-26.48</td><td>45:36:20</td><td>-3.65</td></tr><tr><td>C30 untreated mock-infected cells</td><td>0.57</td><td>106.17 ± 6.57</td><td>N.D</td><td>N.D</td><td>N.D</td></tr><tr><td>C30 untreated infected cells</td><td>0.57</td><td>41.18 ± 6.69</td><td>N.D</td><td>51:23:32</td><td>N.D</td></tr><tr><td>CEmr-3261600</td><td>0.57</td><td>45.80</td><td>10.46</td><td>44:16:01</td><td>-7.13</td></tr><tr><td>CEmr-3269400</td><td>0.57</td><td>48.90</td><td>17.48</td><td>53:03:57</td><td>1.67</td></tr><tr><td>CEmr-3410500</td><td>0.57</td><td>51.22</td><td>22.75</td><td>51:22:46</td><td>-0.01</td></tr></tbody></table>

bovine serum (Eurobio, Courtaboeuf, France), 100 IU/mL penicillin, 0.1 mg/mL streptomycin and 0.25 µg/mL amphotericin B (Eurobio) at 37 °C and 5 % CO2. The screening of antiviral compounds was performed against EHV-1 Kentucky D (KyD) strain (ATCC® VR700TM) at a MOI of 0.01.

## 1 Compounds

Three different libraries including 2,891 compounds were screened in this study: i) 1,199 compounds from the Prestwick® Chemical Library (Prestwick Chemical, Illkirch, France), containing mostly US Food and Drug Administration approved drugs provided at 2 mg/mL in DMSO; ii) 1,651 compounds from the Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN, Caen, France) provided at 10 mM in DMSO; iii) 41 compounds dissolved at 10 mM in DMSO (named herein in-house antiviral library) selected for their effects against different human viruses.

### 1 Screening of compound libraries using the RTCA system

The screening was performed with the RTCA MP system (ACEA Biosciences Inc., San Diego, CA, USA) as previously described [2]. This system measured the impedance signal by the electronic sensor analyser with 6 independent positions for 96-well E-plates (ACEA Biosciences). The impedance signal was derived in a dimensionless value, called Cell Index (CI) and graphically represented [2].

The background readings were obtained with EMEM supplemented in each well of the E-plate view PET (ACEA Biosciences). Cells were then seeded at a density of $1.2 \times 10^4$ per well incubated at room temperature for 30 min, and then placed onto the RTCA-MP station located in the incubator (adapted from [6]). CI values were measured automatically every minute during the first 10 hrs, and then every 15 min for the next 14 hrs.

After 24 hrs of incubation, medium was removed and cells were infected with EHV-1 KyD strain with or without chemical compounds. Control cells were treated with 0.5 % DMSO in presence or absence of the virus. Plates were put back onto the RTCA MP station, and the CI values were recorded every 10 min during 120 h.

The screening was performed under blind conditions and 80 compounds were tested by plate at a final concentration of 10 µg/mL (Preswitck® Chemical Library), 10 µM (CERMN library) or 50, 10, 2 and 0.4 µM (in-house antiviral library) in 0.5 % DMSO. Each plate includes the controls required for calculation of the Z'-factor [5] based on AUCn values between 0 and 120 h post-infection (hpi). The formula is: $Z' = 1 - 3 \times (\sigma^+ + \sigma^-) \div (\mu^+ - \mu^-)$, where $\sigma^+$ and $\sigma^-$ correspond to standard deviations of AUCn for uninfected and infected cells with DMSO, respectively; and $\mu^+$ and $\mu^-$ correspond to means of AUCn for uninfected and infected cells with DMSO, respectively. Only plates presenting a Z'-factor higher than 0.5 were validated for further analysis as
<caption>**Table 3**</caption>

Screening of 41 compounds (in-house antiviral library) selected for their effects against different human viruses at 4 concentrations (0.4, 2, 10 and 50µM). For each compound, the following values are provided: the area under normalised Cell Index curve (AUCn), the %AUCn compared to AUCn of untreated infected cells, the time required for the cell index to decrease by 50 % after virus infection (CIT50) and the ΔCIT50 value obtained by comparing results for treated vs untreated, EHV-1-infected control wells. The Z'-factor was used to assess the quality of the screening in 96-well format. For untreated mock-infected and untreated infected cells, the mean ± SD of AUCn is reported. N.D., not determinable.

<table><thead><tr><th rowspan="2">Compound name</th><th rowspan="2">Supplier</th><th rowspan="2">Z'-factor</th><th colspan="4">AUCn</th><th colspan="4">%AUCn</th><th colspan="4">CIT50</th><th colspan="4">ΔCIT50</th></tr><tr><th>50 µM</th><th>10 µM</th><th>2 µM</th><th>0.4 µM</th><th>50 µM</th><th>10 µM</th><th>2 µM</th><th>0.4 µM</th><th>50 µM</th><th>10 µM</th><th>2 µM</th><th>0.4 µM</th><th>50 µM</th><th>10 µM</th><th>2 µM</th><th>0.4 µM</th></tr></thead><tbody><tr><td>A1 untreated mock-infected cells</td><td></td><td>0.74</td><td>156.79 ± 9.26</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td></tr><tr><td>A1 untreated infected cells</td><td></td><td>0.74</td><td>57.08 ± 2.59</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td><td>31:52:27</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td></tr><tr><td>Mercaptopurine</td><td>Target Mol</td><td>0.74</td><td>41.98</td><td>49.59</td><td>52.52</td><td>50.67</td><td>-39.72</td><td>-19.72</td><td>-12.00</td><td>-16.87</td><td>30:04:57 32:51:02 33:41:02 32:24:07 -1.76</td><td>1.01</td><td>1.84</td><td>0.56</td><td></td><td></td><td></td><td></td></tr><tr><td>Thioguanine</td><td>Target Mol</td><td>0.74</td><td>45.22</td><td>51.94</td><td>51.43</td><td>51.39</td><td>-31.22</td><td>-13.54</td><td>-14.86</td><td>-14.98</td><td>28:14:30 32:05:21 31:41:42 30:27:49 -3.60</td><td>0.24</td><td>-0.15</td><td>-1.38</td><td></td><td></td><td></td><td></td></tr><tr><td>Valganciclovir</td><td>Target Mol</td><td>0.74</td><td>177.47</td><td>131.87</td><td>84.84</td><td>53.52</td><td>316.71</td><td>196.74</td><td>73.03</td><td>-9.38</td><td>147:44:31 28:32:34:47:53:27 33:25:08 115.90</td><td>-3.30</td><td>16.05</td><td>1.57</td><td></td><td></td><td></td><td></td></tr><tr><td>Valaciclovir</td><td>Target Mol</td><td>0.74</td><td>70.89</td><td>48.32</td><td>45.80</td><td>51.60</td><td>36.33</td><td>-23.04</td><td>-29.68</td><td>-14.44</td><td>41:13:30 28:47:46 26:26:57 32:02:04:93.38</td><td>-3.05</td><td>-5.40</td><td>0.19</td><td></td><td></td><td></td><td></td></tr><tr><td>Penciclovir</td><td>Target Mol</td><td>0.74</td><td>63.88</td><td>49.84</td><td>49.04</td><td>48.81</td><td>17.89</td><td>-19.06</td><td>-21.16</td><td>-21.75</td><td>40:47:08 30:46:02 32:17:14 29:24:29 8.94</td><td>-1.08</td><td>0.44</td><td>-2.44</td><td></td><td></td><td></td><td></td></tr><tr><td>Famciclovir</td><td>Target Mol</td><td>0.74</td><td>46.39</td><td>48.66</td><td>47.51</td><td>49.39</td><td>-28.13</td><td>-22.16</td><td>-25.17</td><td>-20.23</td><td>29:21:08 30:34:39:29:56:22:31:01:37 -2.49</td><td>-1.27</td><td>-1.91</td><td>-0.82</td><td></td><td></td><td></td><td></td></tr><tr><td>Maribavir</td><td>Target Mol</td><td>0.74</td><td>51.30</td><td>49.71</td><td>51.46</td><td>53.00</td><td>-15.22</td><td>-19.40</td><td>-14.79</td><td>-10.74</td><td>37:21:43 32:49:24:32:38:31 32:55:22:55.52</td><td>0.98</td><td>0.80</td><td>1.08</td><td></td><td></td><td></td><td></td></tr><tr><td>Didanosine</td><td>Target Mol</td><td>0.74</td><td>54.52</td><td>49.67</td><td>60.00</td><td>49.97</td><td>-6.74</td><td>-19.52</td><td>7.68</td><td>-18.72</td><td>29:37:46 30:05:36:34:56:53:33:17:07 -2.22</td><td>-1.75</td><td>3.10</td><td>1.44</td><td></td><td></td><td></td><td></td></tr><tr><td>Stavudine</td><td>Target Mol</td><td>0.74</td><td>50.28</td><td>49.44</td><td>52.49</td><td>53.54</td><td>-17.89</td><td>-20.11</td><td>-12.08</td><td>-9.33</td><td>31:04:33 29:27:03 31:30:50 32:47:16 -0.77</td><td>-2.39</td><td>-0.33</td><td>0.94</td><td></td><td></td><td></td><td></td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 3 (continued)**</caption><thead><tr><th rowspan="2">Compound name</th><th rowspan="2">Supplier</th><th rowspan="2">Z-factor</th><th colspan="4">AUC<sub>n</sub></th><th colspan="4">%AUC<sub>n</sub></th><th colspan="4">CIT<sub>50</sub></th><th colspan="4">ΔCIT<sub>50</sub></th></tr><tr><th>50 μM</th><th>10 μM</th><th>2 μM</th><th>0.4 μM</th><th>50 μM</th><th>10 μM</th><th>2 μM</th><th>0.4 μM</th><th>50 μM</th><th>10 μM</th><th>2 μM</th><th>0.4 μM</th><th>50 μM</th><th>10 μM</th><th>2 μM</th><th>0.4 μM</th></tr></thead><tbody><tr><td>Lamivudine</td><td>Target Mol</td><td>0.74</td><td>53.84</td><td>52.80</td><td>51.53</td><td>50.36</td><td>-8.52</td><td>-11.26</td><td>-14.60</td><td>-17.67</td><td>32:23:37 33:09:48 31:39:41</td><td>32:07:56</td><td>0.55</td><td>1.32</td><td>-0.18</td><td>0.29</td><td></td></tr><tr><td>Abacavir</td><td>Target Mol</td><td>0.74</td><td>50.57</td><td>53.67</td><td>52.64</td><td>48.42</td><td>-17.14</td><td>-8.99</td><td>-11.68</td><td>-22.80</td><td>26:56:17 32:21:46 32:27:26</td><td>29:59:41</td><td>-4.91</td><td>0.52</td><td>0.61</td><td>-1.85</td><td></td></tr><tr><td>Adefovir dipivoxil</td><td>Target Mol</td><td>0.74</td><td>49.71</td><td>88.67</td><td>119.24</td><td>123.95</td><td>-19.41</td><td>83.10</td><td>163.52</td><td>175.92</td><td>24:16:02 147:44:31 147:44:31 123:32:51</td><td>-7.58</td><td>115.90</td><td>115.90</td><td>91.70</td><td></td></tr><tr><td>Tenofovir disoproxil</td><td>Target Mol</td><td>0.74</td><td>77.88</td><td>62.32</td><td>52.05</td><td>52.19</td><td>54.70</td><td>13.76</td><td>-13.25</td><td>-12.87</td><td>52:52:57 35:46:29 30:56:57 33:05:05</td><td>21.04</td><td>3.93</td><td>-0.90</td><td>1.24</td><td></td></tr><tr><td>Emtricitabine</td><td>Target Mol</td><td>0.74</td><td>48.89</td><td>53.46</td><td>54.12</td><td>49.47</td><td>-21.56</td><td>-9.54</td><td>-7.78</td><td>-20.04</td><td>27:48:05 35:02:51</td><td>32:51:10</td><td>32:05:11</td><td>-4.04</td><td>3.20</td><td>1.01</td><td>0.24</td></tr><tr><td>Capecitabine</td><td>Target Mol</td><td>0.74</td><td>47.51</td><td>50.66</td><td>50.25</td><td>46.70</td><td>-25.17</td><td>-16.89</td><td>-17.99</td><td>-27.30</td><td>31:08:32 30:10:49 32:57:59</td><td>28:44:35</td><td>-0.70</td><td>-1.66</td><td>1.12</td><td>-3.10</td><td></td></tr><tr><td>Cytarabine</td><td>Target Mol</td><td>0.74</td><td>114.38</td><td>95.55</td><td>55.16</td><td>46.30</td><td>150.72</td><td>101.19</td><td>-5.05</td><td>-28.36</td><td>78:35:53 69:03:43 32:45:25 31:02:17</td><td>46.75</td><td>37.22</td><td>0.91</td><td></td><td>-0.81</td><td></td></tr><tr><td>Decitabine</td><td>Target Mol</td><td>0.74</td><td>122.51</td><td>109.26</td><td>97.17</td><td>68.10</td><td>172.12</td><td>137.26</td><td>105.46</td><td>28.98</td><td>42:05:06 106:37:57 58:35:58 41:39:02</td><td>10.24</td><td>74.79</td><td>26.75</td><td>9.81</td><td></td><td></td></tr><tr><td>A2 untreated mock-infected cells</td><td></td><td>0.73</td><td>146.42 ± 9.06</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td>N.D.</td><td></td><td>N.D.</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>A2 untreated infected cells</td><td></td><td>0.73</td><td>38.01 ± 3.00</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td>33:04:09</td><td></td><td>N.D.</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Gemcitabine</td><td>Target Mol</td><td>0.73</td><td>129.33</td><td>121.67</td><td>97.34</td><td>45.70</td><td>240.22</td><td>220.08</td><td>156.07</td><td>20.23</td><td>69:52:01 63:04:07 70:06:21</td><td>36:30:58 38.38</td><td>31.58</td><td>38.62</td><td>5.03</td><td></td><td></td></tr><tr><td>Cidofovir</td><td>Target Mol</td><td>0.73</td><td>34.46</td><td>41.04</td><td>36.73</td><td>35.92</td><td>-9.35</td><td>7.98</td><td>-3.37</td><td>-5.49</td><td>32:43:20 36:28:21</td><td>36:30:37 33:49:02</td><td>1.23</td><td>4.98</td><td>5.02</td><td>2.33</td><td></td></tr><tr><td>Telbivudine</td><td>Target Mol</td><td>0.73</td><td>34.09</td><td>35.57</td><td>33.98</td><td>33.41</td><td>-10.31</td><td>-6.43</td><td>-10.62</td><td>-12.10</td><td>30:24:48 31:52:08 33:40:39 33:54:47</td><td>-1.08</td><td>0.38</td><td>2.19</td><td>2.42</td><td></td></tr><tr><td>Sofosbuvir</td><td>Target Mol</td><td>0.73</td><td>35.77</td><td>34.00</td><td>34.62</td><td>33.15</td><td>-5.89</td><td>-10.55</td><td>-8.92</td><td>-12.78</td><td>33:19:36 32:03:00 30:19:53 30:46:50</td><td>1.84</td><td>0.56</td><td>-1.16</td><td>-0.71</td><td></td></tr></tbody></table>

(continued on next page)
<table><caption>**Table 3 (continued)**</caption><thead><tr><th rowspan="2">Compound name</th><th rowspan="2">Supplier</th><th rowspan="2">Z'-factor</th><th colspan="4">AUC<sub>n</sub></th><th colspan="4">%AUC<sub>n</sub></th><th colspan="4">CIT<sub>50</sub></th><th colspan="4">ΔCIT<sub>50</sub></th></tr><tr><th>50 μM</th><th>10 μM</th><th>2 μM</th><th>0.4 μM</th><th>50 μM</th><th>10 μM</th><th>2 μM</th><th>0.4 μM</th><th>50 μM</th><th>10 μM</th><th>2 μM</th><th>0.4 μM</th><th>50 μM</th><th>10 μM</th><th>2 μM</th><th>0.4 μM</th></tr></thead><tbody><tr><td>Chloroquine</td><td>Sigma</td><td>0.61</td><td>55.41</td><td>43.43</td><td>40.23</td><td>43.76</td><td>0.40</td><td>-31.11</td><td>-39.53</td><td>-30.26</td><td>57:21:37</td><td>45:32:2542</td><td>11:31</td><td>43:08:51</td><td>12.25</td><td>0.43</td><td>-2.92</td><td>-1.96</td></tr><tr><td>Hydroxychloroquine sulfate</td><td>MedChemExpress</td><td></td><td>60.03</td><td>49.60</td><td>42.39</td><td>49.96</td><td>12.55</td><td>-14.90</td><td>-33.85</td><td>-13.95</td><td>58:09:18</td><td>52:26:41</td><td>40:18:29</td><td>42:33:29</td><td>13.05</td><td>7.34</td><td>-65.58</td><td>-2.55</td></tr><tr><td>A5 untreated mock-infected cells</td><td></td><td>0.66</td><td>149.38 ± 8.96</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td></tr><tr><td>A5 untreated infected cells</td><td></td><td>0.66</td><td>53.33 ± 7.05</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td><td>42:10:51</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td></tr><tr><td>Aphidicolin</td><td>Santa Cruz Biotechnology</td><td>0.66</td><td>154.19</td><td>132.47</td><td>131.57</td><td>59.30</td><td>265.34</td><td>208.20</td><td>205.81</td><td>15.71</td><td>137:40:02</td><td>203:18:19</td><td>11:15:23</td><td>45:44:2095</td><td>49</td><td>59.69</td><td>47.64</td><td>2.12</td></tr><tr><td>A6 untreated mock-infected cells</td><td></td><td>0.78</td><td>29.88 ± 4.16</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td></tr><tr><td>A6 untreated infected cells</td><td></td><td>0.78</td><td>109.64 ± 4.03</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td><td>30:12:49</td><td></td><td></td><td></td><td>N.D.</td><td></td><td></td><td></td></tr><tr><td>Brequinar</td><td>Adoq Bio-science</td><td>0.78</td><td>8.93</td><td>19.30</td><td>33.42</td><td>30.61</td><td>-55.11</td><td>-27.84</td><td>9.33</td><td>1.94</td><td>0:22:31</td><td>25:28:27</td><td>36:12:01</td><td>33:25:59</td><td>-29.84</td><td>-4.74</td><td>5.99</td><td>3.22</td></tr><tr><td>Ribavirin</td><td>MedChemExpress</td><td></td><td>94.17</td><td>51.39</td><td>25.11</td><td>31.45</td><td>169.13</td><td>56.60</td><td>-12.55</td><td>4.13</td><td>57:34:04</td><td>49:31:47</td><td>28:18:30</td><td>32:55:08</td><td>27.35</td><td>19.32</td><td>-1.91</td><td>2.71</td></tr></tbody></table>
CERMN library

<figure><img src="image_5.png" /></figure>

<figure><img src="image_6.png" /></figure>

Preswick® Chimeical library

<figure><img src="image_7.png" /></figure>

<figure><img src="image_8.png" /></figure>

In-house antiviral library

<figure><img src="image_9.png" /></figure>

<figure><img src="image_10.png" /></figure>

**Fig. 1.** Dataset screening of 2,891 chemical compounds from three libraries to identify EHV-1 inhibitors. The CERMN library (A, B) was screened at 10 µM, Prestwick® Chemical library (C, D) at 10 µg/mL and in-house antiviral library (E, F) at 4 concentrations (0.4, 2, 10 and 50 µM). The percentage of area under normalised Cell Index (CI) from 0 to 96 hpi of treated cells compared to mock-treated cells (%AUC~n~) were reported graphically for each library. The red line represents the cut-off 25 % from which compound could identified as potential antiviral compounds against EHV-1 (A, C, E). The increase of the time required for the CI to decrease by 50 % after virus infection (CIT~50~) of treated cells compared to mock-treated cells (ΔCIT~50~) were reported graphically for each library. The red line represents the cut-off 8 h of delay from which compound could identified as potential antiviral compounds against EHV-1 (B, D, F). The original figure can be found online in Supplementary figure 1 ([1]) at https://doi.org/10.1016/j.antiviral.2020.104931.

previously described by Thieulent et al. (2019) [2]. CI values were first normalised using the
RTCA software version 2.0 (ACEA Biosciences) prior to data analysis according to the manufac-
turer's recommendations. For each compound, the area under normalised Cell Index (CI) curves
was calculated from 0 to 96 hrs post-infection (hpi) (AUCn; [3]). The%AUCn was calculated with
formula:
$%\text{AUCn} = \frac{(\text{AUCn compound} - \text{AUCn untreated cells infected})}{\text{AUCn untreated cells infected}} \times 100$. The time required for the CI to decrease by 50% after virus infection was also determined ($\text{CIT}_{50}$; [4]), and compared with untreated cells infected with EHV-1 KyD strain ($\Delta\text{CIT}_{50} = \text{CIT}_{50} \text{ compound} - \text{CIT}_{50} \text{ untreated cells infected}$).

## Declaration of Competing Interest

The authors declare that they have no known competing financial interests or personal relationships which have, or could be perceived to have, influenced the work reported in this article.

## Acknowledgments

This work was supported by LABÉO, IFCE (Institut Français du Cheval et de l'Equitation, projects AMIE and SAVE), Fonds Eperon (projects N87-2014, N07-2015, N07-2016, N13-2017 and N62-2017), Région Normandie (CPER R25 P3) and CENTAURE European project co-funded by Normandy County Council, European Union in the framework of the ERDF-ESF operational programme 2014-2020. We thank Christophe Denoyelle and Emilie Brotin from ImpedanCELL, Normandie Univ, UNICAEN, Caen, France for interacting and for their technical assistance with RTCA technology. We also thank all collaborators of the SAVE project.

## Supplementary Materials

Supplementary material associated with this article can be found in the online version at doi:10.1016/j.dib.2020.106492.

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