# POU1F1 wt Allele

National Cancer Institute

## Source

National Cancer Institute. POU1F1 wt Allele. NCI Thesaurus. Code C133845.

Human POU1F1 wild-type allele is located in the vicinity of 3p11.2 and is approximately 17 kb in length. This allele, which encodes pituitary-specific positive transcription factor 1 protein, plays a role in pituitary development and hormone expression. Mutations in this gene results in combined pituitary hormone deficiency.