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124. Frenzel, E.; Wrenger, S.; Immenschuh, S.; Koczulla, R.; Mahadeva, R.; Deeg, H.J.; Dinarello, C.A.; Welte, T.; Marcondes, A.M.; Janciauskiene, S. Acute-phase protein alpha1-antitrypsin-a novel regulator of angiopoietin-like protein 4 transcription and secretion. *J. Immunol.* **2014**, *192*, 5354–5362. [CrossRef] [PubMed]

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126. Rahman, M.S.; Imran, K.M.; Hossain, M.; Lee, T.J.; Kim, Y.S. Biochanin A induces a brown-fat phenotype via improvement of mitochondrial biogenesis and activation of AMPK signaling in murine C3H10T1/2 mesenchymal stem cells. *Phytother. Res.* **2021**, *35*, 920–931. [CrossRef] [PubMed]

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130. Berglund, E.D.; Li, C.Y.; Bina, H.A.; Lynes, S.E.; Michael, M.D.; Shanafelt, A.B.; Kharitonenkov, A.; Wasserman, D.H. Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity. *Endocrinology* **2009**, *150*, 4084–4093. [CrossRef] [PubMed]

131. Hui, Q.; Huang, Z.; Pang, S.; Yang, X.; Li, J.; Yu, B.; Tang, L.; Li, X.; Wang, X. Two-hundred-liter scale fermentation, purification of recombinant human fibroblast growth factor-21, and its anti-diabetic effects on ob/ob mice. *Appl. Microbiol. Biotechnol.* **2019**, *103*, 719–730. [CrossRef] [PubMed]

132. Ye, X.; Qi, J.; Yu, D.; Wu, Y.; Zhu, S.; Li, S.; Wu, Q.; Ren, G.; Li, D. Pharmacological efficacy of FGF21 analogue, liraglutide and insulin glargine in treatment of type 2 diabetes. *J. Diabetes Complicat.* **2017**, *31*, 726–734. [CrossRef] [PubMed]

133. Kim, H.W.; Lee, J.E.; Cha, J.J.; Hyun, Y.Y.; Kim, J.E.; Lee, M.H.; Song, H.K.; Nam, D.H.; Han, J.Y.; Han, S.Y.; et al. Fibroblast growth factor 21 improves insulin resistance and ameliorates renal injury in db/db mice. *Endocrinology* **2013**, *154*, 3366–3376. [CrossRef]

134. Ye, X.; Qi, J.; Wu, Y.; Yu, D.; Xu, P.; Li, S.; Zhu, S.; Wu, Q.; Ren, G.; Li, D. Comparison of PEGylated FGF-21 with insulin glargine for long-lasting hypoglycaemic effect in db/db mice. *Diabetes Metab.* **2015**, *41*, 82–90. [CrossRef] [PubMed]

135. Veniant, M.M.; Komorowski, R.; Chen, P.; Stanislaus, S.; Winters, K.; Hager, T.; Zhou, L.; Wada, R.; Hecht, R.; Xu, J. Long-acting FGF21 has enhanced efficacy in diet-induced obese mice and in obese rhesus monkeys. *Endocrinology* **2012**, *153*, 4192–4203. [CrossRef]

136. Xu, J.; Stanislaus, S.; Chinookswong, N.; Lau, Y.Y.; Hager, T.; Patel, J.; Ge, H.; Weiszmann, J.; Lu, S.C.; Graham, M.; et al. Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models–association with liver and adipose tissue effects. *Am. J. Physiol. Endocrinol. Metab.* **2009**, *297*, E1105–E1114. [CrossRef] [PubMed]

137. Gaich, G.; Chien, J.Y.; Fu, H.; Glass, L.C.; Deeg, M.A.; Holland, W.L.; Kharitonenkov, A.; Bumol, T.; Schilske, H.K.; Moller, D.E. The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes. *Cell Metab.* **2013**, *18*, 333–340. [CrossRef] [PubMed]

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139. Charles, E.D.; Neuschwander-Tetri, B.A.; Pablo Frias, J.; Kundu, S.; Luo, Y.; Tirucherai, G.S.; Christian, R. Pegbelfermin (BMS-986036), PEGylated FGF21, in Patients with Obesity and Type 2 Diabetes: Results from a Randomized Phase 2 Study. *Obesity* **2019**, *27*, 41–49. [CrossRef] [PubMed]
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