# Involvement of poly-unsaturated fatty acid omega-3 in the regulation of feeding behaviour of rainbow trout

Jérôme Roy

► To cite this version:

Jérôme Roy. Involvement of poly-unsaturated fatty acid omega-3 in the regulation of feeding behaviour of rainbow trout. 19th international lipidomic meeting: Lipids: from Sea to fork, Sep 2024, Brest, France. hal-05076581

HAL Id: hal-05076581

https://hal.inrae.fr/hal-05076581v1

Submitted on 21 May 2025

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7 sessions

Endorsed diversity of lipids from assets to drug use

Benefits of lipids and their distribution

100 markers in human metabolism: genes and cell states

Lipids to their role in health: epidemiology, prevention and treatment

Advances in lipid research: current and future directions

Emerging technologies and new areas of research

New progress in lipid research

Welcome to IUEM, Brest/Plouzané

On behalf of the organising committees, we delighted to welcome you the 19th GERLI Lipidomics meeting.

The meeting is hosted at the European Institute for Marine Studies (IUEM), a multidisciplinary institution in the field of marine and coastal sciences. It is located above "the Goulet de Brest", a 3 km long - 1.5 km large strait linking the Bay of Brest and the Atlantic Ocean.

GERLI 2024 meeting is bringing together more than 100 leading researchers from 13 countries (UK, Portugal, Ireland, Spain, Hong Kong, Canada, Mauritania, Norway, USA, Belgium, Germany, United Arab Emirates, France).

The meeting will follow a single session format to maximize the opportunity for inter-disciplinary exchanges. We have a schedule planned with, at the time of writing, 13 plenary speakers, 33 oral communications and 39 posters.

Oral communications should last no more than 12 min and will be followed by 3 min questions/discussion. A best oral communication award will be given to young scientist.

We have interspersed the poster sessions through the meeting creating multiple opportunities of scientific exchanges. The pitch of all posters will be presented during a friendly "flash talk session" (1 minute -1 slide) at the first day of the meeting. Posters will be exposed for the whole duration of the meeting.

On Monday 23, a visit of the Bay of Brest is scheduled on Monday 23rd from 19:00 to 20:30.

On Tuesday 24th, GERLI association will have its annual assembly prior the Gala dinner at Les Ateliers des Capucins (Brest city center).

On behalf of all organisers of GERLI 2024, we would like to thank all our generous sponsors and we hope you have a memorable week in Brest/Plouzané!

You will find below the detailed program of oral communication and the list of presented posters sorted by sessions.

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PROGRAM

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23-26 September, 2024
19TH GERLI MEETING

Plouzané, FRANCE

MONDAY 23 SEPTEMBER

01:45PM - 06:00PM

Opening of the 19th GERLI Meeting

Thesis prices

Session 1 - Structural diversity of lipids from summits to deep sea

Flash poster

Boat tour in Bay of Brest

TUESDAY 24 SEPTEMBER

08:45AM - 05:00PM

Session 2 - Roles/functions of lipids and derivatives

Talk sponsors

Poster session

Session 4 - Lipids in their socio-economic context and legal boundaries

Gala dinner - Ateliers des capucins
PROGRAM

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23-26 September, 2024

19TH GERLI MEETING

Plouzané, FRANCE

WEDNESDAY 25 SEPTEMBER

08:45PM - 06:00PM

Session 3 - Lipid markers in trophic ecology : promises and dead ends

Session 5 - Environmental/climatic and supply issues of omega 3

Session 6 - GERLI/SFN: Marine lipids and nutrition

THURSDAY 26 SEPTEMBER

08:45AM - 12:50PM

Session 7 - New progress in lipid methodology

Poster session

Awards - Junior talks
13:00

OPENNING

13:45

WELCOME

P. Soudant & M. Mathieu-Resuge

14:00 K. Tighanimine
Thesis price GERLI - Glycerol-3-phosphate and Phosphoethanolamine homeostatic switch triggers senescence by rewiring lipid metabolism.

14:15 T. Guerbette
Thesis price GERLI/SFN - High fat diet induces bioenergetic adaptations of small intestinal epithelial cells reducing cell differentiation and enhancing intestinal permeability in mice

Session 1

STRUCTURAL DIVERSITY OF LIPIDS FROM SUMMITS TO DEEP SEA
CHAIR: C. LEBLANC

14:30 E. Schneck
Plenary speaker - Influence of glycolipids on the physical properties of lipid membranes: insights through x-ray and neutron scattering

15:00 S. Finnerty
Biodiversity, bioactivity and lipid diversity of microphytobenthic biofilms from coastal intertidal sediments

15:15 Y. Sérès
Characterization of digalactosyldiacylglycerol synthases in the model diatom *Phaeodactylum tricornutum*

15:30 Flash Poster 1min/poster presentation of all posters

16:15

COFEE BREAK

16:45 S. Coffinet
Plenary speaker - Microbial membrane lipids as a tool to track microbial metabolisms in the environment: case study in continental wetlands

17:15 E.J.S.
Claereboudt
Sterol Biodiversity in Holothuroids

17:30 F.F. Hsu
Total structural analysis of the diversified lipid in *Micrococcus luteus* cells by multiple stage mass spectrometry with high resolution mass spectrometry

17:45 J. Cui
Function and biotechnological application of the glycine-glucolipid in the marine bacterium *Alcanivorax borkumensis*

18:15

BUS FROM PNBI TO BREST HARBOUR

19:00

BRESTOA

Tour boat in the Bay of Brest. Departure from Brest harbour (1h30)
Session 2

ROLES/FUNCTIONS OF LIPIDS AND DERIVATES

CHAIR: T. DURAND

<table><tr><td>08:45</td><td>J.C.Y. Lee</td><td><u>Plenary speaker</u> - Exploring the Status of polyunsaturated Fatty Acids and Isoprostanes in Marine Species Exposed to Environmental Stress</td></tr><tr><td>09:15</td><td>C. Oger</td><td>Oxygenated PUFA Metabolites as Biomarkers in Marine Environment</td></tr><tr><td>09:30</td><td>M. Carletti</td><td>The Seipin protein of <i>Phaeodactylum tricornutum</i>: structure and function specificities</td></tr><tr><td>09:45</td><td>A. Toussaint</td><td>Transcription factors for reprogramming lipid metabolism in response to temperature in the simple green <i>Picoalga ostreococcus tauri</i></td></tr><tr><td>10:00</td><td>E. Stahl</td><td>Lipid-mediated signalling mechanisms in plant innate immunity</td></tr></table>

10:15

COFFEE BREAK

<table><tr><td>10:45</td><td>M. Zonnequin</td><td>Characterizing molecular actors from brown algal oxylipin pathways in defense signaling through metabolomics and functional genomics</td></tr><tr><td>11:00</td><td>C. Doose</td><td>Non-enzymatic oxylipin production in a mudflat microphytobenthic biofilm: evidence of diatom response to light</td></tr><tr><td>11:15</td><td>Schaller H.</td><td>Phytosterol metabolism and homeostasis</td></tr><tr><td>11:30</td><td>S. Yan</td><td>Role of peroxisome and peroxisomal β-oxidation in lipid remodeling and plant adaptation to phosphate starvation in higher plants</td></tr></table>

11:45

SPONSORS SHORT TALKS: SCIEX, MICROPHYT, LIPOLYTHECH

12:15

LUNCH

14:00

POSTER SESSION

Session 4

LIPIDS IN THEIR SOCIO-ECONOMIC CONTEXT AND LEGAL BOUNDARIES

CHAIR: R. DOMINGUES

<table><tr><td>15:00</td><td>A. Rodrigues</td><td><u>Plenary speaker</u> - An Industry Perspective on Microalgae Lipids: Economics, Regulations, and Societal Impact</td></tr><tr><td>15:30</td><td>E. Masson</td><td>Eating Omega 3 rich products: knowledge and perceptions according to sources</td></tr><tr><td>15:45</td><td>L. Harrault</td><td>Lipid traceability by molecular and isotopic fingerprinting</td></tr></table>

16:00

COFFEE BREAK

<table><tr><td>16:30</td><td>F. Daurès</td><td><u>Plenary speaker</u> - Sardines or how to meet the challenges of sustainability and food security in the context of climate change.</td></tr></table>

17:00

GERLI ASSEMBLY

<table><tr><td>19:00</td><td>GALA DINNER</td><td>Atelier des Capucins - Awards best young posters</td></tr></table>
Session 3

LIPID MARKERS IN TROPHIC ECOLOGY: PROMISES AND DEAD ENDS

CHAIR: F. SARDENNE

08:45 G. Schaal **Plenary speaker** - Lipids and stable isotopes in trophic ecology: what are we measuring?

09:15 M. Marinier Trophic ecology of three deep-sea coral species, interannual comparison using trophic biomarkers

09:30 F. da Costa Sterol biosynthesis and phytosterol bioconversion in *Crassostrea gigas* larvae

09:45 A. Bec **Plenary speaker** - Impact of dietary lipid compounds on the metabolic rate of an aquatic consumer

10:15

COFFEE BREAK

10:45 S. kolodzey Algae to Alkanes: New insights into the potential of alkanes as detrital biomarkers from kelp degradation experiments

11:00 J. Vigliano Relva Temperature-driven changes in fatty acids from diatoms to copepods modulate direct effects of temperature on copepod fitness.

Session 5

ENVIRONMENTAL/CLIMATIC AND SUPPLY ISSUES OF OMEGA 3

CHAIR: M. VAGNER

11:15 J. Roy **Plenary speaker** - Omega-3 fatty acids and their influence on feeding behavior in rainbow trout: unraveling the sensory mechanisms

11:45 L. Ghinter The heart's energy secrets: lipids to grease mitochondrial performance in sardines, *Sardina pilchardus*

12:00 M. Péron Spatial and ontogenetic modulation of fatty acid composition in juvenile European sea bass (*Dicentrarchus labrax*) from two French estuaries

12:15

LUNCH

14:00 F. Beaudoin **Plenary speaker** - Production of omega-3 VLC-PUFAs in transgenic *Camelina sativa*: A vision for extending the story from nutraceutical to therapeutic applications.

14:30 A. Guillot Processing seafood: a major driver in omega-3 and trace element composition?

14:45 C. Parrish Replacement of Fish Oil by a High-DHA Microbial Oil in Salmon Diets: Effect on Lipid Molecular Species and Gene Expression

15:00 L. Jeunet Autotrophic and heterotrophic production of omega-3 long chain polyunsaturated fatty acids (n-3 LC-PUFA) in the Iroise Sea.

Session 6

GERLI/SFN: MARINE LIPIDS AND NUTRITION

CHAIR: M. HACHEM

15:15 M. Linder **Plenary speaker** - Marine lecithin: From rich LC-PUFA sources to health benefits
15:45 N.M. Bandarra Chub mackerel and quinoa improve brain DHA levels and n-3/n-6 ratio in Alzheimer's disease

16:00 COFFEE BREAK

16:30 B. Miralles-Pérez Metabolic and Brain Effect of Marine Lipids as Phospholipids vs Triacylglycerides on Aged Mice: A Lipidomics plus Proteomics Research

16:45 M. Hachem Production, Molecular Modeling and Investigation of Lysophospholipids-DHA Crossing using an in vitro Human Model of Blood Brain Barrier

17:00 C. Vors Direct impact of dietary plant-based glycolipids on human gut microbiota and inflammation: first evidence from in vitro models

17:15 L. Couëdelo Impact of structuring DHA in marine lipids on its intestinal absorption and metabolic fate

17:30 J. Delarue Plenary speaker - Marine omega 3 fatty acids and insulin-resistance
Session 7

NEW PROGRESS IN LIPID METHODOLOGY

CHAIR: L. HARRAULT

<table><tr><td>08:45</td><td>F. Rey</td><td><u>Plenary speaker</u> - Marine lipidomics: a valuable tool to design innovative solutions for the valorisation of marine organisms</td></tr><tr><td>09:15</td><td>M. Buscaglia</td><td>Bioproduction of 13C-labeled docosahexaenoic acid (DHA) by the protist <i>Aurantiochytrium mangrovei</i> and the dinoflagellate <i>Cryptothecodinium cohnii</i></td></tr><tr><td>09:30</td><td>H. Launay</td><td>In-situ monitoring of lipid hydrolysis at the molecular and supramolecular level by Nuclear Magnetic Resonance</td></tr></table>

09:45

POSTER SESSION

10:15

COFFEE BREAK

<table><tr><td>10:45</td><td>A.P. Alonso</td><td><u>Plenary speaker</u> - Comparative Omics Provide Insights into the Synthesis of Unusual Fatty Acids in Alternative Crops</td></tr><tr><td>11:15</td><td>A. Meyer</td><td>Determination of lipid oxidation status in different matrices and determination of fat parameters for edible oils by NMR</td></tr><tr><td>11:30</td><td>M.S. Miettinen</td><td>The NMRlipids Databank: Enhancing Lipidomics Research through Programmatic Access to Molecular Simulation Trajectories</td></tr><tr><td>11:45</td><td>M.Y. Golovko</td><td>12-Hydroxyeicosatetraenoic acid is the only enzymatically produced HETE increased under brain ischemia</td></tr></table>

12:00

SPONSOR SHORT TALK: FERMENTALG

12:10

AWARDS - OLD BONES & BEST YOUNG RESEARCHER TALKS

12:30

LUNCH

14:00

Lipidomyste Days
## Session 1 STRUCTURAL DIVERSITY OF LIPIDS FROM SUMMITS TO DEEP SEA

S1-1 T. Labed-Veydert
Atmospheric deposition (wet and dry) is a significant source of fatty acids for ecosystems?

S1-2 M.V. Sidi Boune
Taxonomic identification by DNA barcoding of several Mauritanian macroalgae and comparison of their lipid profile

S1-3 J. Lehoux
Multi-step total synthesis of phenolic phytoprostanes

S1-4 E. Chavonet
Exploring the variability of cuticle compounds in different grapevine cultivars

S1-5 R. Pais
Uncovering the Functional Lipidome of *Dunaliella salina*: Bioactive Lipids with Potential Nutraceutical Applications

S1-6 J. Batista
Upgrading the lipidome of *Gelidium corneum* biomass and by-products as sources of added-value lipids and bioactive ingredients

S1-7 D. Lopes
Exploring the lipidome of *Ulva rigida*: Unlocking its potential as a source of bioactive lipids

S1-8 C. Brehelin
Lipid metabolism during dormancy of sweet cherry floral buds: preponderance of 3-hydroxylated FAs in MGDG

S1-9 F. Safi
First characterization of the lipid composition of a giant virus membranes

S1-10 F. Domergue
Functional characterization of a plastidial cytochrome b5-fused Δ4 desaturase from *Ostreococcus tauri* in higher plants

S1-11 R. Domingues
Temperature and salinity induce modulation of the lipidome of the microalga *Tetraselmis striata* CTP4: a lipidomics investigation

## Session 2 ROLES/FUNCTIONS OF LIPIDS AND DERIVATES

S2-1 J. Joubès
Investigating herbicide targets in the very long-chain fatty acid biosynthetic pathway

S2-2 A. Sire de Vilar
Lipid dynamics in the Cold-Water Coral *Dentomuricea aff. meteor*: Effects of ocean warming and reproductive condition

S2-3 T. Durand
Oxidative stress mitigation in horticultural crops using foliar applications of *Ilex paraguariensis* extract: a dose-dependent study

S2-4 R. Millot
Changes in lipid and fatty acid contents of gonad during the reproductive cycle of the Mediterranean swordfish *Xiphias gladius*

## Session 3 LIPID MARKERS IN TROPHIC ECOLOGY: PROMISES AND DEAD ENDS

S3-1 A. Voisin
Cracking the Code: advancing fatty acid analyses in Antarctic benthic species by Gas Chromatography-Mass Spectrometry.

S3-2 M.V. Sidi Boune
The yellow mullet fish oil from the Banc d'Arguin Imrâguens in Mauritania: An example of polyunsaturated fatty acids transfer from diatoms to the fish within the alimentary chain

## Session 4 LIPIDS IN THEIR SOCIO-ECONOMIC CONTEXT AND LEGAL BOUNDARIES

S4-1 B. Fel
Episomal CRISPR-Cas9 and polyploidization methods for microalgae, production of non-GMO mutants according to UE standards
Session 5

LIPIDS IN THEIR SOCIO-ECONOMIC CONTEXT AND LEGAL BOUNDARIES

S5-1 M. Bertrand

Evaluation of n-3 LC PUFA synthesis in the liver of European sardines deficient in DHA for two months

S5-2 A.S.P. Moreira

Seasonal plasticity of algae lipidome in response to environmental variations: evidence from *Ulva rigida* cultivated in a sustainable integrated multi-trophic aquaculture

Session 6

GERLI/SFN: MARINE LIPIDS AND NUTRITION

S6-1 A. Gomes-Bispo

Study of the impact of a diet enriched in chub mackerel and quinoa on the hepatic lipid fraction and its DHA status in Alzheimer's disease

S6-2 R. Gomes

Diets enriched in chub mackerel increase erythrocytes DHA levels and improve omega-3 index in Alzheimer's disease

S6-3 L. Pruvost

Chondroitin sulfate nano vectorized by LC-PUFAs nanocarriers, both extracted from salmon (*Salmo salar*) by green process

S6-4 T. Conde

Polar lipids from marine microalgae show strong anti-inflammatory effects against LPS-induced macrophages

S6-5 M.C. Michalski

Dietary sphingolipids impact circulating ceramide species: new insights using stable isotope tracing of sphingosine in Caco-2/TC7 intestinal cells

S6-6 V. Ciesielski

Quantification of pentadecanoic acid (C15:0) in marine species and dairy products

S6-7 M. Gerlei

Lipolysis of Marine liposomal solutions naturally rich in LC-PUFAs by phospholipases: a comparative *in vitro* gastrointestinal digestion study with marine emulsion.

S6-8 F. Marques

Evaluation of Biosolvents and Ultrasound-Assisted Extraction for Lipid Recovery from *Chlorella vulgaris*, *Fucus vesiculosus* and *Ulva* sp.: A Sustainable Approach for Food and Nutraceutical Applications

S6-9 N. Barouh

Lipid content in Chlorella biomass: variability related to biomass origin

Session 7

NEW PROGRESS IN LIPID METHODOLOGY

S7-1 N. Gueguen

Genome-scale Metabolic Networks for better understanding of lipid metabolism and production

S7-2 T. Melo

Ultrasonic-assisted food-grade extraction using ethanol for obtaining high-value-added lipids from *Nannochloropsis oceanica*

S7-3 L. Fouillen

A combined lipidomic and proteomic profiling of *Arabidopsis thaliana* plasma membrane

S7-4 B. Yang

Resolving Triacylglycerol and Glycerolphospholipid Regioisomers of Marine Lipids Using Mass Spectrometry and Machine Learning
Session 7

NEW PROGRESS IN LIPID METHODOLOGY

<table><tr><td>S7-6</td><td>N. Barouh</td><td>Release of free fatty acids in Chlorella biomass during post-harvesting steps</td></tr><tr><td>S7-7</td><td>J. Bertrand-Michel</td><td>Navigating Lipidomics: Key Challenges and Perspectives in Lipid Nomenclature for Biologists</td></tr><tr><td>S7-8</td><td>J. Bertrand-Michel</td><td>Metatoul-Lipidomic Facility: Cutting-Edge Lipidomics for Metabolic Research</td></tr><tr><td>S7-9</td><td>J. Bertrand-Michel</td><td>MetaboHUB (French national infrastructure in metabolomics and fluxomics for life sciences), towards next generation metabolomics and fluxomics: from population to single cells.</td></tr><tr><td>S7-10</td><td>C. Quezada</td><td>Development of an in-situ monitoring system to study the rheological changes during the in vitro gastric digestion of O/W emulsions and its impact on intestinal release of free fatty acids</td></tr><tr><td>S7-11</td><td>A.P. Alonso</td><td>Exploring Fatty Acid Synthesis in Alternative Crops via 13C-Labeling Approaches</td></tr></table>
SPONSOIRS

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Avanti®
POLAR LIPIDS, INC.

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GATTEFOSSÉ

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lipotype

Lipidomics for a better life

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Polaris

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microphyt

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BIOTECHNOLOGIES

GREENSEA

Marine Bioactives

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Lipolytech®

SCIEX

maison
CHANCERELLE
1828

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Fermentalg

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Larodan

Research Grade Lipids

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ELSEVIER

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Euro Fed Lipid

european federation for the science and technology of lipids

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Société Française
de Nutrition

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UBO
CNRS
IRD

INSTITUT
UNIVERSITAIRE
EUROPEEN
DE LA MER

WBO
Université de Bretagne Occidentale

cnrs

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LEMAR

laboratory of environmental

marine sciences

UBO | CNRS | IRD | Ifremer

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Biologie et Écologie des
Ecosystèmes marins Profonds

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ISblue

The interdisciplinary
graduate school
for the blue planet

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Ifremer