Introduction: The use of digital health devices (e-health) would improve certain patient’s clinical outcomes. Proposing effective “online” interventions to improve patients’ adaptation to chronic conditions requires a validated measure of digital health literacy. The “Lisane” self-report measure was developed and validated by experts. Objectives: This article describes the field-testing of the preliminary version of the tool, more specifically the non-response rate, ceiling and floor effects, item redundancy and the preliminary assessment of its internal consistency. Method: The Lisane tool, consisting of 14 items divided into five domains (e-literacy, reliability of information on the Internet, relevance of information to personal health, protection of privacy, empowerment), was applied to a convenience sample (29 participants) recruited in Quebec (patient communities) and Switzerland (clinical setting). The non-response rate and the ceiling and floor effects were evaluated. Item redundancy was described for exploratory purposes. Internal consistency was assessed using Cronbach's alpha coefficient. Results: The rate of missing results > 15% and a redundancy (r = 0.94, p<0.05) on power to act’s items were noted. A floor effect was identified. Cronbach’s alpha was α= 0.90, 95% CI [0.78 – 1.03]. Discussion and Conclusion: The field test of the Lisane tool has limitations, such as a ceiling effect and the indication of redundancy in certain items, but good preliminary evidence of internal consistency. Continued analysis of its psychometric properties (validity, reliability) is necessary.