# Bupivacaine Hydrochloride

National Cancer Institute

## Source

National Cancer Institute. Bupivacaine Hydrochloride. NCI Thesaurus. Code C28876.

A long-acting, amide-type local anesthetic. Bupivacaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation.