# Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

Warren A Cheung, Xiaojian Shao, Andréanne Morin, Valérie Siroux, Tony Kwan, Bing Ge, Dylan Aïssi, Lu Chen, Louella Vasquez, Fiona Allum, et al.

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Warren A Cheung, Xiaojian Shao, Andréanne Morin, Valérie Siroux, Tony Kwan, et al. Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome. Genome Biology, 2017, 18 (1), pp.89. 10.1186/s13059-017-1173-7. [https://hal-04304740v2](https://hal-04304740v2)

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# Correction to: Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

Warren A. Cheung<sup>1,2†</sup>, Xiaojian Shao<sup>1,2†</sup>, Andréanne Morin<sup>1,2†</sup>, Valérie Siroux<sup>3</sup>, Tony Kwan<sup>1,2</sup>, Bing Ge<sup>1,2</sup>, Dylan Aïssi<sup>3</sup>, Lu Chen<sup>4,5</sup>, Louella Vasquez<sup>4</sup>, Fiona Allum<sup>1,2</sup>, Frédéric Guénard<sup>6</sup>, Emmanuelle Bouzigon<sup>7</sup>, Marie-Michelle Simon<sup>2</sup>, Elodie Boulier<sup>2</sup>, Adriana Redensek<sup>2</sup>, Stephen Watt<sup>4</sup>, Avik Datta<sup>8</sup>, Laura Clarke<sup>8</sup>, Paul Flicek<sup>8</sup>, Daniel Mead<sup>4</sup>, Dirk S. Paul<sup>9,10</sup>, Stephan Beck<sup>9</sup>, Guillaume Bourque<sup>1,2</sup>, Mark Lathrop<sup>1,2</sup>, André Tchernof<sup>11</sup>, Marie-Claude Vohl<sup>6</sup>, Florence Demenais<sup>7</sup>, Isabelle Pin<sup>3,12</sup>, Kate Downes<sup>5,13</sup>, Hendrick G. Stunnenberg<sup>14</sup>, Nicole Soranzo<sup>4,5,15,16</sup>, Tomi Pastinen<sup>1,2*</sup> and Elin Grundberg<sup>1,2*</sup>

**Correction to: Genome Biol**

https://doi.org/10.1186/s13059-017-1173-7

Following publication of the original article [1], the authors reported an error in Additional file 1. The updated Additional file 1 is given below.

**Additional file**

**Additional file 1** Description of MCC-Seq capture panel. This file contains: (1) summary of CpGs and genomic regions targeted by the MCC-Seq capture panel design (xlsx Excel spreadsheet format), and (2) a list of the targeted regions (.bed text file). (ZIP 4405 kb)

**Author details**

Received: 25 April 2019 Accepted: 25 April 2019

Published online: 07 May 2019

**Reference**

1. Cheung, et al. Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome. Genome Biol. 2017;18:50. https://doi.org/10.1186/s13059-017-1173-7.

Full list of author information is available at the end of the article

<footnote n="1"><sup>1</sup>Department of Human Genetics, McGill University, Montreal, Quebec, Canada. <sup>2</sup>McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada. <sup>3</sup>Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Inserm U1209, CNRS, University Grenoble Alpes, Institute for Advanced Biosciences, Grenoble, France.</footnote>

<footnote n="4"><sup>4</sup>Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.</footnote>

<footnote n="5"><sup>5</sup>Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Long Road, Cambridge CB2 0PT, UK. <sup>6</sup>Institute of Nutrition and Functional Foods (INAF), Laval University, Québec, QC G1V 0A6, Canada. <sup>7</sup>Genetic Variation and Human Diseases Unit, UMR-946, INSERM, Université Paris Diderot, Université Sorbonne Paris Cité, Paris, France.</footnote>

<footnote n="8"><sup>8</sup>European Molecular Biology Laboratory, European Bioinformatics Institute,</footnote>

<footnote>Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK. <sup>9</sup>UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, UK. <sup>10</sup>Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK. <sup>11</sup>Québec Heart and Lung Institute, Laval University, Québec, QC G1V 4G5, Canada. <sup>12</sup>Pédiatrie, Centre Hospitalier Universitaire (CHU) Grenoble Alpes, Grenoble, France. <sup>13</sup>National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Long Road, Cambridge CB2 0PT, UK. <sup>14</sup>Faculty of Science, Department of Molecular Biology, Radboud University, Nijmegen 6525GA, The Netherlands.</footnote>

<footnote n="15"><sup>15</sup>British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK. <sup>16</sup>The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics, University of Cambridge, Strangeways Research Laboratory, Wort's Causeway, Cambridge CB1 8RN, UK.</footnote>

<footnote>* Correspondence: tomi.pastinen@gmail.com; tomi.pastinen@mcgill.ca; elin.grundberg@mcgill.ca</footnote>

<footnote><sup>†</sup>Warren A. Cheung, Xiaojian Shao and Andréanne Morin contributed equally to this work.</footnote>

<footnote n="1"><sup>1</sup>Department of Human Genetics, McGill University, Montreal, Quebec, Canada</footnote>