# PDGFRB Gene Rearrangement

National Cancer Institute

## Source

National Cancer Institute. PDGFRB Gene Rearrangement. NCI Thesaurus. Code C84272.

Rearrangement of the PDGFRB gene, resulting in the formation of a fusion transcript and aberrant tyrosine kinase activity. It has been described in myeloid malignancies usually presenting as chronic myelomonocytic leukemia.