# PDGFRA Gene Rearrangement

National Cancer Institute

## Source

National Cancer Institute. PDGFRA Gene Rearrangement. NCI Thesaurus. Code C84271.

Rearrangement of the PDGFRA gene, resulting in the formation of a fusion transcript and aberrant tyrosine kinase activity. It has been described in hematologic malignancies usually presenting as chronic eosinophilic leukemia.