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## SUPPORTING INFORMATION

Additional supporting information can be found online in the Supporting Information section at the end of this article.

**How to cite this article:** Van Den Bossche, Tim, Jean Armengaud, Dirk Benndorf, Jose Alfredo Blakeley-Ruiz, Madita Brauer, Kai Cheng, Marybeth Creskey, et al. 2025. "The Microbiologist's Guide to Metaproteomics." *iMeta* 4, e70031. https://doi.org/10.1002/imt2.70031