# Piritrexim Isethionate

National Cancer Institute

## Source

National Cancer Institute. *Piritrexim Isethionate*. NCI Thesaurus. Code C91407.

The isethionate salt of piritrexim, a synthetic antifolate agent with antiparasitic, antipsoriatic and antitumor properties. Piritrexim inhibits the enzyme dihydrofolate reductase enzyme, thereby disrupting folate metabolism and DNA synthesis and cell division.