This study investigates the diverse meanings of the term “intoxication” as it appears in six distinct contexts within the Holy Qur’an, emphasizing their coherence and the absence of contradiction. It underscores the indispensable role of Quranic context in interpretation and the scholarly efforts to elucidate its nuances. Through inductive, deductive, and analytical methods, the research aims to identify a unified conceptual core of the term, revealing its varied implications—ranging from mental obscuration, magic and possession, misguidance, and the physical intoxicant, to confusion and the soul’s departure at death. Structured into an introduction, two chapters, and a conclusion, the study affirms that contextual analysis is essential for accurate exegesis.