# EF-2 Peptide

National Cancer Institute

## Source

National Cancer Institute. *EF-2 Peptide*. NCI Thesaurus. Code C49064.

A synthetic peptide derived from the protein ESW/FLI1 type 2 with potential use in cancer immunotherapy. EWS/FLI1 is a fusion protein frequently found in patients with Ewing's sarcoma or primitive neuroectodermal tumors (PNET). Vaccination with EF-2 peptide may stimulate the host immune response to elicit a cytotoxic T-cell response against tumor cells that express this EWS/FLI1 type 2 fusion protein.