# LEF1 wt Allele

National Cancer Institute

## Source

National Cancer Institute. <u>LEF1 wt Allele</u>. NCI Thesaurus. Code C80033.

Human LEF1 wild-type allele is located within 4q23-q25 and is approximately 121 kb in length. This allele, which encodes lymphoid enhancer-binding factor 1 protein, is involved in the mediation of both transcription and signal transduction. Genetic variation may be associated with both the occurrence and relapse of acute lymphoblastic leukemia.