# Enantiopure cycloplatinated pentahelicenic N-heterocyclic carbenic complexes that display long-lived circularly polarized phosphorescence

Debsouri Kundu, Natalia del Rio, Marie Cordier, Nicolas Vanthuyne, Emma

V Puttock, Stefan C J Meskers, J. A. Gareth Williams, Monika

Srebro-hooper, Jeanne Crassous

► To cite this version:

Debsouri Kundu, Natalia del Rio, Marie Cordier, Nicolas Vanthuyne, Emma V Puttock, et al.. Enantiopure cycloplatinated pentahelicenic N-heterocyclic carbenic complexes that display long-lived circularly polarized phosphorescence. Dalton Transactions, 2023, 10.1039/d3dt00577a. hal-04088974

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Cite this: DOI: 10.1039/d3dt00577a

# Enantiopure cycloplatinated pentahelicenic N-heterocyclic carbenic complexes that display long-lived circularly polarized phosphorescence†

Debsouri Kundu,ª Natalia del Rio,ª Marie Cordier,ª Nicolas Vanthuyne, ID b

Emma V. Puttock, ID c Stefan C. J. Meskers, ID d J. A. Gareth Williams, ID *c

Monika Srebro-Hooper ID *e and Jeanne Crassous ID *a

Received 23rd February 2023,
Accepted 16th April 2023

DOI: 10.1039/d3dt00577a

rsc.li/dalton

The preparation of the first enantiopure cycloplatinated complexes bearing a bidentate, helicenic N-heterocyclic carbene and a diketonate ancillary ligand is presented, along with their structural and spectroscopic characterization based on both experimental and computational studies. The systems exhibit long-lived circularly polarized phosphorescence in solution and in doped films at room temperature, and also in a frozen glass at 77 K, with dissymmetry factor $g_{lum}$ values $\ge 10^{-3}$ in the former and around $10^{-2}$ in the latter.

## Introduction

N-heterocyclic carbenes (NHCs) have become classical ligands for organometallic and coordination chemistry¹ thanks to their strong σ-donor abilities that result in the formation of stable metal–carbon bonds. The introduction of chirality in NHC-based complexes has opened up a variety of applications for such molecules, for example in enantioselective catalysis² and chiral materials science.³ Meanwhile, there has been intensive research into phosphorescent complexes of heavy metals,⁴,⁵ such as iridium(III) and platinum(II), including systems with NHC ligands, due to their importance as triplet-harvesting phosphors in organic light-emitting diodes (OLEDs).⁶,⁷

The design of chiral emitters displaying intense circularly polarized luminescence (CPL) has attracted significant interest, thanks to the potential of circularly polarized (CP) light in a diverse range of applications from OLEDs and optical information processing to bio-imaging and chiral sensing.⁸ For example, CP-OLEDs offer an interesting approach to improve the performance of high-resolution displays by eliminating the need for anti-glare polarized filters, which can account for the

loss of up to 50% of the emitted light.⁹ Although many types of chiral NHC-complexes with diverse stereogenic elements have been developed to date, especially for enantioselective catalysis, there are very few examples of enantiopure chiroptical materials based on NHC-Pt complexes, and they are mainly limited to those bearing monodentate NHCs.¹⁰

Our group has developed chiral versions of several classes of organometallic compounds,¹¹ including complexes incorporating helical NHCs,¹² with intriguing emission properties such as long-lived CP phosphorescence. Inspired by the work of Strassner and co-workers on phosphorescent Pt(II) complexes with (:C^C)-cyclometalating NHC ligands,⁷b,¹³ we tackled the synthesis of their helical analogues. As a result, we describe here the preparation and characterization of the first-of-their-kind enantiopure helicenic NHC-based Pt(II) complexes (see Scheme 1) displaying long-lived CP phosphorescence in solution (both at room and low temperatures) and in thin films (at room temperature). Enantiopure complexes of the form Pt(O^O)(:C^C) have been synthesized, where (:C^C) is an NHC ligand incorporating a [5]helicene unit, and (O^O) is a β-diketonate ligand, i.e. either acetyl-acetonate, acac (Pt1) or dibenzoylmethane anion, dbm (Pt2). The photophysical (absorption and emission) and chiroptical properties (optical rotation – OR, electronic circular dichroism – ECD, and CPL) of Pt1 and Pt2 have been studied both experimentally and computationally.

## Results and discussion

### Synthesis and structural studies

Following the strategy previously developed in our group to prepare helical NHC ligands,¹² the starting imidazole-fused pentahelicene 1 was subjected to N-arylation with 4-iodoani-

<figure><img src="image_3.png" /></figure>

<footnote>ªUniversité de Rennes, CNRS, ISCR – UMR 6226, 35000 Rennes, France.</footnote>

<footnote>E-mail: jeanne.crassous@univ-rennes1.fr</footnote>

<footnote>ᵇAix Marseille University, CNRS Centrale Marseille, iSm2, 13284 Marseille, France</footnote>

<footnote>ᶜDepartment of Chemistry, Durham University, Durham DH1 3LE, UK.</footnote>

<footnote>E-mail: j.a.g.williams@durham.ac.uk</footnote>

<footnote>ᵈMolecular Materials and Nanosystems and Institute for Complex Molecular Systems, Technische Universiteit Eindhoven, NL 5600, The Netherlands</footnote>

<footnote>ᵉFaculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Krakow, Poland. E-mail: srebro@chemia.uj.edu.pl</footnote>

<footnote>†Electronic supplementary information (ESI) available. CCDC 2207037. For ESI and crystallographic data in CIF or other electronic format see DOI: https://doi.org/10.1039/d3dt00577a</footnote>
Paper

Dalton Transactions

<figure><img src="image_4.png" /><figcaption>**Scheme 1** Synthesis of helicene-NHC-Pt(II) complexes Pt1 and Pt2: (i) 4-iodoanisole, Cul, L-proline, DMSO, 110 °C, 63 h; (ii) CH₃I, CH₃CN, reflux, 16 h (43%, over the 2 steps); (iii) Ag₂O, 1,4-dioxane, rt, 16 h; (iv) cis-Pt(DMSO)₂Cl₂, toluene, reflux, 16 h; (v) 2,4-pentanedione (acacH) or dibenzoylmethane (dbmH), Na₂CO₃, toluene, reflux, overnight (35% for Pt1 and 58% for Pt2, over the 3 steps).</figcaption></figure>

sole using CuI/L-proline as the catalytic system (Ullman-type coupling), as presented in Scheme 1,¹⁴ to yield 3N-(2-anisyl)-[5]helicene-imidazole (2). Methylation with MeI in acetonitrile led to the imidazolium iodide salt 3 with an overall yield of 43% over the two steps. Reaction of the salt with silver(I) oxide, followed by transmetalation with cis-Pt(DMSO)₂Cl₂,¹⁰d gave the cycloplatinated intermediate, which was treated without further purification with acacH or dbmH and Na₂CO₃ in refluxing toluene, to obtain (rac)-Pt1 or (rac)-Pt2, respectively, in moderate yields (35% for Pt1 and 58% for Pt2 for the three steps).¹⁵ The identity of the final complexes was confirmed by ¹H and ¹³C NMR spectroscopy and mass spectrometry (see ESI†). For instance, the imidazolium proton in compound 3 resonating at 10.70 ppm is not present in the ¹H NMR spectra of Pt1 and Pt2, while a signal corresponding to the CH proton of the β-diketonate appears at respectively 5.53 and 6.80 ppm in the products.

In addition, suitable crystals of racemic **Pt2** for X-ray diffraction analysis were obtained by slow evaporation of a dichloromethane solution at room temperature (Fig. 1 and ESI†). The resulting (rac)-Pt2·CH₂Cl₂ crystallized in the P̄ triclinic space group. The d⁸ Pt(II) ion adopts a slightly distorted square-planar geometry. The metric data of the Pt(II) coordination sphere (metal-ligand bond lengths and valence angles) are in the range typical for those reported for other (·C·C)Pt(acac)

complexes,⁷b,13,15 with the NHC and (O^O) ligands situated within the same plane and the coordinated anisole phenyl and NHC rings being almost coplanar (twist angle of 1.58°). The Ccarbene⁻Pt bond distance of 1.940(3) Å is similar to that in other NHC-platinum compounds previously described.⁷b,13,15 The complex assembles into heterochiral dimers organized in a head-to-tail fashion, with π-π interactions between co-ordinated NHC and anisole phenyl rings of opposite helices (centroid-centroid distance of 3.625 Å); see Fig. 1b and c. The intramolecular Pt-Pt distances of 5.772(2) Å are far longer than in other NHC-Pt(II) derivatives reported in the literature (d(Pt-Pt) = 3.276–3.495 Å),⁷b,13,15 evidently showing that Pt-Pt interactions are inhibited by the steric hindrance imposed by the helicene unit. Regarding the helicene moiety, it exhibits a helicity angle (dihedral angle between terminal rings) of 49.3°, which is typical for [5]helicenes and consistent with those measured for similar helicene-NHC ligands.¹² These observations indicate extended π-conjugation across the whole (anisole-NHC-helicene-Pt-β-diketonate) molecular system and efficient electronic interaction between the helicene-NHC ligand and the metal, as also supported by the calculated iso-surfaces of the frontier molecular orbitals (vide infra, Fig. 2e). Note also that, according to the density functional theory (DFT) computations (see ESI† for a description of computational details used in this study and a full set of calculated results), **Pt2** can be assumed to exist in solution as an equal mixture of practically isoenergetic rotamers of the phenyl groups in the dbm moiety (see Fig. S2.1 in ESI†), near-coplanarity of which ensures effective π-electron conjugation within this ligand.¹³b

## Photophysical and chiroptical properties

Both of the racemic complexes, **Pt1** and **Pt2**, were then resolved into their constituent enantiomers using HPLC over a chiral stationary phase, yielding (*P*)-(+)- and (*M*)-(-) enantiomers with enantiomeric excess (ee) values between 98 and 99.5% (see ESI†), and their absorption and emission properties were examined.

The UV-vis absorption spectra of **Pt1** and **Pt2** were recorded in toluene at room temperature (10⁻⁵ M), and they are presented in Fig. 2a; note that all ε and Δε values in this work are

<figure><img src="image_5.png" /><figcaption>**Fig. 1** (a) X-ray crystallographic molecular structure of Pt2 in (rac)-Pt2·CH₂Cl₂ along with (b) its supramolecular (head-to-tail) organization into a heterochiral dimer (two views), with π-π interactions and Pt···Pt distances of 3.625 Å and 5.772(2) Å, respectively.</figcaption></figure>
<figure><img src="image_6.png" /></figure>

<figure><img src="image_7.png" /><figcaption>**Fig. 2** Experimental (a) UV-visible absorption and (b) ECD spectra of (*P*)-(+) and (*M*)-(−) enantiomers of **Pt1** and **Pt2** measured in toluene at room temperature (*C* = 1 × 10⁻⁵ M) along with the corresponding TDDFT-simulated spectra (panels (c) and (d), respectively; results for the lowest-energy rotamer (l) of **Pt2** shown). (e) Isosurfaces (±0.04 au) of MOs involved in selected electronic transitions of **Pt1** and **Pt2**. See ESI† for a full set of computed data including the electronic assignment of the spectra.</figcaption></figure>

given in units of M⁻¹ cm⁻¹. Both complexes exhibit overall very similar spectral envelopes with intense bands at wavelengths shorter than 330 nm, attributable to π-π* transitions within (mainly) the extended π-helical unit (*vide infra*),¹¹,¹⁶ and additional bands of lower intensity at longer wavelengths (ε = 1000–10 000 at λ > 380 nm). It can be seen that the **Pt2** complex exhibits almost uniformly higher UV-vis intensity than **Pt1**.

The ECD spectra of both complexes, **Pt1** and **Pt2**, were also recorded in toluene at room temperature. As depicted in Fig. 2b, the (*P*) and (*M*) enantiomers of each system display the expected mirror-image ECD envelopes. For example, (*P*)-**Pt1** demonstrates two strong positive bands at 309 (+23.9) and 341

(+55.1), accompanied by a positive shoulder at 356 nm (+35.6), and a weak negative band at 401 nm (−2.6). Similarly, (*P*)-**Pt2** shows two strong positive bands at 307 (+20) and 341 (+52.8) with a positive shoulder at 353 nm (+44.4), additional positive bands at 376 (+19) and 390 nm (+11.1), and a very weak negative band at 408 nm (−0.7). As can be seen, both systems demonstrate very similar ECD both in shape and energetic position and magnitude of particular bands, except for the region between about 375 and 400 nm where **Pt2** shows significantly increased intensity compared to **Pt1**. Finally, specific optical rotations (in deg cm³ g⁻¹ dm⁻¹) were measured in toluene for both complexes with values [α]²³D = ±950 for **Pt1** and ±749 for **Pt2** (C = 1.0 mg mL⁻¹).
<figure><img src="image_8.png" /></figure>

Considering that specific solvent effects and vibronic con-
tributions have not been taken into account in the calcu-
lations, the simulated UV-vis and ECD spectra (computed
using time-dependent DFT (TDDFT) with PBE0//SDD/SV(P) and
the continuum solvent model for toluene)¹⁷ agree satisfactorily
with the experimental data (Fig. 2; see also the Computational
details section and Fig. S2.2 in ESI†). In particular, energetic
positions and signs of the bands are correctly reproduced by
the theory along with an increased UV-vis intensity within the
examined spectral range and enhanced ECD intensity of the
low-energy tail of the spectra observed for **Pt2** vs. **Pt1**. The cal-
culations also reproduce correctly the decrease in specific
optical rotation values that accompanies the change from acac
in **Pt1** to dbm in **Pt2** (with the better numerical agreement
between experimental and theoretical results obtained for the
BHLYP functional in line with the previously observed
trends,¹⁸ see Table S2.1 in ESI†).

Analysis of molecular orbital (MO) pair contributions to computed excitations shows that for both complexes, the main UV-vis and (positive) ECD intensity observed experimentally between about 300 and 375 nm originates from excitations predominantly corresponding to π-π* transitions within NHC-helicene ligand mixed with anisole → NHC-helicene intraligand charge transfer (ILCT), β-diketonato → NHC-helicene ligand-ligand CT (LLCT) and platinum(II) → NHC-helicene metal-ligand CT (MLCT), *vide infra*. See, for example, excitations no. 3 and 7 for **Pt1** and no. 5 and 11 for **Pt2**, calculated at respectively 349 and 316 nm (Fig. 2c and d, and ESI†), with the lower-energy excitation involving HOMO, HOMO-1, LUMO, LUMO+1 for **Pt1** and HOMO, HOMO-1, LUMO+1, LUMO+2 for **Pt2** (see Fig. 2e and ESI†). Note that the aforementioned **Pt2** rotameric structures considered in the computations demonstrate practically identical UV-vis spectra and very similar ECD envelopes that differ mostly only in the intensity of the higher-energy bands but without a change in the dominant electronic character of the underlying excitations (see ESI†). The lowest-energy excitations calculated for **Pt1** (no. 1 (389 nm) and 2 (365 nm)) also involve the aforementioned frontier MOs but they are mainly assigned to anisole-Pt → NHC-helicene ILCT and MLCT, and demonstrate rather

modest oscillator (*f*) and rotatory strength (*R*) values. On the
contrary, at wavelength longer than 350 nm, four excitations
were computed for **Pt2**, all of enhanced *f* and/or *R* as compared
to **Pt1** in line with increased UV-vis and ECD intensity
observed in this spectral region for the dbm-based Pt complex.
These excitations (no. 1 (394 nm), 2 (385 nm), 3 (365 nm), 4
(362 nm)) also involve the frontier MOs and collectively show
strong anisole-Pt → NHC-helicene ILCT and MLCT character
but with admixture of anisole-NHC-helicene-Pt → dbm LLCT
and MLCT due to the presence of the extended π-electron
system within the phenyl-substituted β-diketonate ligand
resulting in the dbm-centred LUMO¹³ᵇ (see Fig. 2 and ESI†). In
particular, the lowest-energy excitation no. 1 for **Pt2** corres-
ponds to almost pure HOMO → LUMO anisole-NHC-Pt → dbm
LLCT and MLCT and demonstrates negative rotatory strength.
Finally, it should be highlighted that the aforementioned
additional π-chromophoric dbm unit in **Pt2** clearly contributes
to an increased UV-vis intensity observed for this complex
compared to **Pt1** even at shorter wavelengths (around 300 nm);
see for example excitation no. 13 computed at 308 nm (Fig. 2c
and ESI†) and assigned to anisole-Pt-dbm → dbm π-π* tran-
sition mixed with ILCT, LLCT, and MLCT.

Both complexes are luminescent in deoxygenated toluene solution at room temperature. The emission spectrum recorded for Pt1 (Fig. 3a; see also Table 1 for numerical data) displays some vibrational structure, with a (0,0) band at about 530 nm, whilst the (0,1) component at about 560 nm is the most intense; these wavelengths correspond to a vibrational progression of 1300 cm⁻¹ associated with the C=C stretch of the aromatics, quite typical of many phosphorescent cyclometalated complexes.¹⁹ The quantum yield under these conditions is 5%. The spectrum of Pt2 covers a similar spectral region to that of Pt1 but lacks any clear vibrational structure, despite a higher quantum yield of 9%. Much of the previous literature on NHC-Pt(II) complexes reports quantum yields only in films, rather than in solution,⁷,¹³ so a direct comparison of the aforementioned quantum yield values for Pt1 and Pt2 with those obtained for related non-helicenic complexes is not readily possible. Compared to classical NHC-Pt systems, however, it appears that the helicene ligand imparts greater

<figure><img src="image_9.png" /><figcaption>**Fig. 3** Experimental emission spectra of **Pt1** and **Pt2** upon excitation at 400 nm: (a) in deoxygenated toluene solution at 295 K, (b) in butyronitrile at 77 K, and (c) in PMMA film (2 wt%) at 295 K under an atmosphere of nitrogen gas. See also Table 1 for numerical data.</figcaption></figure>
<figure><img src="image_10.png" /></figure>

<table><caption>**Table 1** Photophysical properties of Pt1 and Pt2 complexes under the conditions indicated</caption><thead><tr><th rowspan="2">Complex</th><th rowspan="2">Absorption in toluene at 295 K<br>λ<sub>max</sub>/nm (ε/10<sup>3</sup> M<sup>-1</sup> cm<sup>-1</sup>)</th><th colspan="4">Emission in toluene at 295 K<sup>a</sup></th><th colspan="4">Emission in PMMA film (2% w/w) at 295 K<sup>b</sup></th><th colspan="2">Emission in C<sub>3</sub>H<sub>7</sub>CN at<br>77 K</th></tr><tr><th>λ<sub>max</sub>/nm</th><th>Φ<sub>lum</sub></th><th>τ/μs</th><th>k<sub>r</sub>/s<sup>-1</sup></th><th>Σk<sub>nr</sub>/s<sup>-1</sup></th><th>λ<sub>max</sub>/nm</th><th>Φ<sub>lum</sub></th><th>τ/μs</th><th>k<sub>r</sub>/s<sup>-1</sup></th><th>Σk<sub>nr</sub>/s<sup>-1</sup></th><th>λ<sub>max</sub>/nm</th><th>τ/μs</th></tr></thead><tbody><tr><td>Pt1</td><td>306 (32.9), 338 (22.4), 383 (7.24),<br>402 (4.56), 441 (1.1)</td><td>526, 562, 605</td><td>0.05</td><td>290</td><td>170</td><td>3300</td><td>528, 562, 609</td><td>0.31</td><td>3200<sup>c</sup></td><td>97</td><td>216</td><td>512, 556, 601, 657</td><td>3700</td></tr><tr><td>Pt2</td><td>308 (37.9), 336 (30.3), 385 (10.5),<br>403 (7.23), 441 (1.27)</td><td>546</td><td>0.09</td><td>65</td><td>1400</td><td>14 000</td><td>532, 555</td><td>0.23</td><td>1200<sup>c</sup></td><td>192</td><td>642</td><td>511, 554, 599, 654</td><td>6400</td></tr></tbody></table>

<sup>a</sup> Values refer to degassed solutions; the quantum yields Φ<sub>lum</sub> were measured relative to [Ru(bpy)<sub>3</sub>]Cl<sub>2</sub> in aqueous solution for which Φ<sub>lum</sub> = 0.04.<sup>b</sup> Data were recorded for thin films under an atmosphere of nitrogen gas; spectra and quantum yields were measured using an integrating sphere.<sup>c</sup> The decays in films do not fit to a single-exponential decay owing to heterogeneity in the environment of the molecules in the film: the quoted values are amplitude-weighted average lifetimes obtained from fitting to the sum of two exponential decays, as shown in Fig. S1.15 in ESI.†

rigidity to the complex that helps to reduce some of the deactivation pathways. Overall, the obtained quantum yields are in the same range as those reported for other helicene-NHC-transition-metal complexes.<sup>11,12</sup>

The luminescence decays mono-exponentially in both cases, with a lifetime of 290 µs for Pt1 and 65 µs for Pt2. The fact that the lifetime is significantly shorter for Pt2, despite its higher quantum yield, suggests that the emission is “more allowed” (exhibits a higher participation of Pt orbitals) in Pt2 than in Pt1. Further insight may be obtained by estimating the radiative k<sub>r</sub> and non-radiative Σk<sub>nr</sub> rate constants, assuming that the emitting state is formed with unit efficiency, through the relationships k<sub>r</sub> = Φ/τ and Σk<sub>nr</sub> = (1 − Φ)/τ. Such an analysis gives k<sub>r</sub> values of 1400 and 170 s<sup>-1</sup> for Pt2 and Pt1, respectively. The order of magnitude difference suggests that the emissive excited state has significantly different orbital parentage in the two complexes. Conversely, the non-radiative decay is faster in Pt2 than in Pt1, the estimated Σk<sub>nr</sub> values being 14 000 and 3300 s<sup>-1</sup>, respectively. Strassner and coworkers also observed a disappearance of a clear vibrational structure and substantial decrease in the lifetime of emission upon changing from acac to dbm in related Pt(II) complexes with a dibenzofuran NHC ligand, albeit in thin film rather than in fluid solution.<sup>13</sup> In that case, however, the changes were accompanied by a drop in the quantum yield and a significant red-shift in the emission (not observed in Pt2), features that were attributed to the phenyl rings of the dbm extending the π-electron system of this ligand,<sup>13b</sup> vide infra.

In a frozen glass in butyronitrile (C<sub>3</sub>H<sub>7</sub>CN) at 77 K, the vibronic structure becomes very well defined for both complexes, with λ(0,0) = 514 nm in both cases (Fig. 3b and Table 1). Under these conditions, the lifetimes for Pt1 and Pt2 become very long (3.7 and 6.4 ms, respectively). This behaviour is consistent with a largely ligand-centred state localized on an extended π-electron system, as observed in some of our previous studies on complexes of other metals like Ir(III) and Re(I) with helicene ligands.<sup>12a,c,e,20</sup> Note that very similar vibrationally structured phosphorescence signals were recorded in 2-methyltetrahydrofuran (2-MeTHF) at 77 K (see Fig. 4c).

The CPL spectra of (P) and (M) enantiomers of the Pt1 and Pt2 complexes were initially recorded in degassed toluene at room temperature (Fig. 4a and b). Pleasingly, well-structured CPL responses were obtained for both complexes, with dissymmetry factors g<sub>lum</sub> = 2(I<sub>L</sub> − I<sub>R</sub>)/(I<sub>L</sub> + I<sub>R</sub>) of +5 × 10<sup>-3</sup> for (M)-Pt1 and −3.9 × 10<sup>-3</sup> for (P)-Pt1 at 546 nm, and of +1.8 × 10<sup>-3</sup> for (M)-Pt2 and −1.9 × 10<sup>-3</sup> for (P)-Pt2 at 543 nm. Note that while the measured CPL spectra demonstrate overall similar shape, some bands have different signs for Pt1 and Pt2. The CPL responses were then also recorded in a glass of 2-MeTHF at 77 K (Fig. 4c).<sup>21</sup> To our delight, the (P) and (M) enantiomers of both systems revealed mirror-image signals in the same region as the non-polarized fluorescence. In this case, the measured g<sub>lum</sub> values were 1.3 × 10<sup>-2</sup> for Pt1 and 6.2 × 10<sup>-3</sup> for Pt2, the former being one of the highest values reported up to now for Pt-helicene derivatives.<sup>7a,11,16b</sup> Unlike for the signals recorded in toluene at room temperature, the corresponding enantio-
<figure><img src="image_11.png" /></figure>

<figure><img src="image_12.png" /></figure>

<figure><img src="image_13.png" /></figure>

<figure><img src="image_14.png" /><figcaption>**Fig. 4** Experimental luminescence and CPL spectra of (P) and (M) enantiomers of (a) **Pt1** and (b) **Pt2** in degassed toluene at room temperature (298 K), and of (c) **Pt1** and **Pt2** in degassed 2-MeTHF at low temperature (77 K); C = 10⁻⁵ M, λ<sub>ex</sub> = 365 nm. (d) Plot of g<sub>lum</sub> values with emission wavelength obtained for 2 wt% PMMA film of **Pt1** enantiomers; λ<sub>ex</sub> = 313 nm. (e) and (f) Comparison of g<sub>lum</sub> values for **Pt1** enantiomers obtained at room temperature in toluene and at low temperature in 2-MeTHF, respectively.</figcaption></figure>

<figure><img src="image_15.png" /></figure>

<figure><img src="image_16.png" /></figure>

<figure><img src="image_17.png" /></figure>

mers of **Pt1** and **Pt2** display opposite CPL signs at 77 K (for (P) enantiomer: positive for **Pt1** vs. negative for **Pt2**). Note also that, interestingly, the more resolved CPL spectra at room temperature offer the advantage of observing the vibronic structure, contrary to the non-polarized luminescence (Fig. 4a and b).<sup>16c</sup> Meanwhile, at 77 K, both CPL and non-polarized phosphorescence become well-resolved and the vibronic structure appears clearly in Fig. 4c.

Fig. 4e and f display the *g*<sub>lum</sub> values of **Pt1** enantiomers at room and low temperature, respectively, and the results are interesting to comment. Typically, if an optical transition derives from just two electronic states, ground and excited, then its *g*<sub>lum</sub> value should be constant throughout the emission band. This is clearly not the case for the complexes examined here at room temperature, as visible in Fig. 4e for **Pt1**.

There might be thus several electronic excited states involved in the signal under this condition. In addition, vibronic mixing may be involved in the excited states. Indeed, due to vibrational motion in the excited states, two different electronic states could get mixed. This very commonly leads to rapid variations in the *g*<sub>lum</sub> value across the emission band.<sup>21,22</sup> The electronic states that get mixed into the lowest excited state each bring their own electric and magnetic transition dipole moments.

To shed some light on the electronic origin of the emissive properties for **Pt1** and **Pt2**, TDDFT calculations were then performed involving T<sub>1</sub> excited-state geometry optimizations. Representative results can be found in Fig. 5, which presents the electron density differences between the ground state and the excited state computed for both complexes, with their
<figure><img src="image_18.png" /><figcaption>**Fig. 5** Left: Electron density differences between the S₀ ground state and T₁ excited state, Δρ = ρg - ρe, color-mapped on ρg (isosurfaces: ±0.0001 au) for Pt1 and Pt2 (in two conformations) based on the TDA-TDDFT-PBE0/SDD/SV(P) PCM(toluene) calculations. Electron density moves from the red region to the blue region when moving from the excited state to the ground state. Right: The corresponding computed T₁ → S₀ phosphorescence wavelengths along with dominant MO-pair contributions (isosurfaces: ±0.04 au) to emission transition. See ESI† for a full set of calculated data.</figcaption></figure>

negative (red)/positive (blue) values corresponding to outflow/
inflow of electron density accompanying T₁ → S₀ phosphor-
escence transition, along with the corresponding dominant
MO-pair contributions. See Fig. S2.8–S2.12 and Tables S2.7,
S2.8 in ESI† for additional calculated data.

As can be seen from Fig. 5 and data presented in the ESI,†
the computations reproduce correctly the experimental ener-
gies of **Pt1** and **Pt2** emission, and in the case of **Pt2** seem to
confirm that the existence of (structurally and/or electronically)
different excited states may indeed be responsible for its
experimentally observed emission features. Namely, for this
system several T₁ excited-state structures were obtained includ-
ing the expected (practically isoenergetic) rotamers (I–IV) of
the phenyl groups in the dbm moiety corresponding to S₀
ground-state geometries, but also structures with the carbon
C(Ph)C(H)C(Ph) chain of the dbm core deviated out the plane
of the metalcycle OPtO and the two phenyl rings in the dbm

ligand arranged more closely to planarity with this chain (II'
and II" of slightly higher energy compared to I–IV); see
Fig. S2.8 and Tables S2.7, S2.8.† The aforementioned rotameric
T₁ structures of **Pt2**, as illustrated for the conformer II in Fig. 5
(see also ESI†), show essentially the same emission wavelength
as that calculated for **Pt1** along with the same electronic origin
that corresponds to predominantly NHC-helicene-centred ³ππ*
state with some NHC-helicene → anisole-Pt ³MLCT and ³ILCT
character (see alternating inflow (blue) and outflow (red) of
electron density within the π-system of NHC-helicene moiety
along with accumulation of electron density around the metal
centre accompanying T₁ → S₀ transition visible in the electron
difference densities for **Pt1** and **Pt2-II** shown in the left part of
Fig. 5; compare also with Fig. S2.12†). Note that going to the
T₁ equilibrium **Pt2** structures of this type, there is some reor-
ganization among the frontier unoccupied MOs (LUMO and
LUMO+1) as compared to their corresponding S₀ equilibrium
<figure><img src="image_19.png" /></figure>

structures, with a significant energetic stabilization of the NHC-helicene-centred π*-orbital, which accordingly becomes LUMO and results in a change of the assignment for T₁ → S₀ phosphorescence transition vs. S₀ → S₁ absorption (vide supra). The structural modifications observed in the T₁ Pt2-II' and Pt2-II" geometries, on the other hand, seem to favour extended π-delocalization within the β-diketonate ligand leading to a decrease in its corresponding π*-orbital energy, such that in these structures the LUMO is localized on the (O^O) ligand, as observed in the ground-state structures of this system. Consequently, the corresponding T₁ → S₀ transition in such conformers appears blue-shifted as compared to that in rotamers I-IV, and is assigned as predominantly dbm-centred (phenyl → core) ³ILCT admixed with dbm → anisole-NHC-helicene-Pt ³MLCT and ³LLCT, as visible in Fig. 5 and ESI.† Note that similar assignment was proposed for the related dbm-NHC-dibenzofuran Pt(n) complex.¹³b Finally, it is worth noting that while solvation (toluene vs. THF used as a model for 2-MeTHF) effects simulated in the computations *via* polarizable continuum model do not appear to affect the calculated emission wavelength, they significantly change the relative percentage of MO-pair contributions to the emission transition (see ESI†), thus additionally influencing the electronic character of the emitting state depending on the solvent. All this indicates that, depending on measurement conditions such as temperature and environment/solvent, the emission signal observed for Pt1 and Pt2 may stem either from one or from several emitting states of similar or different orbital parentage. This conclusion accords well with the experimental findings. For example, the phosphorescence emission originated from Pt2-II'-type T₁ structure (with visibly enhanced metal orbitals' involvement as compared to Pt1, see Fig. 5) is consistent with the higher radiative rate constant observed for Pt2 vs. Pt1, and (cautiously speculating) it may be a reason for a change in the sign of the CPL signal observed experimentally for both systems (for *P* enantiomer: positive for Pt1 vs. negative for Pt2). The co-existence of several emitting states of slightly different emission wavelengths and electronic origins accounts also for a complicated picture of the CPL responses observed experimentally for both complexes at room temperature. Of importance, might be also the aforementioned mixing of different (higher-energy) electronic states into the emitting excited-state.²¹,²² Further computational studies, including spin-orbit coupling effects and possibly higher-order correlated methods, are needed to provide a detailed rationalization of all the experimental results for Pt1 and Pt2,²⁰c,²¹,²³ which we plan to report for these and other related systems elsewhere in the future.

Due to the long-lived phosphorescence of these helicene-NHC-based platinum(u) complexes, and hence the potential for triplet-triplet quenching, the solid-state luminescence properties of compounds Pt1 and Pt2 were better studied in amorphous poly(methyl methacrylate) (PMMA) films at room temperature with 2 wt% emitter concentration under inert conditions. The recorded emission spectra are shown in Fig. 3c. As can be seen, the spectrum of Pt1 is similar to the spectrum

obtained in toluene solution, with three vibrational components resolved. The spectrum of Pt2 shows a more resolved spectral profile than the largely featureless spectrum observed in solution, no doubt reflecting the more rigid environment in the polymer host. The quantum yields are elevated compared to those recorded in solution, rising to 31 and 23% for Pt1 and Pt2, respectively, which can reasonably be attributed to a decrease in the non-radiative decay processes. The emission in the films under an inert atmosphere is very long-lived. Neither case shows the temporal decay following single exponential kinetics, no doubt reflecting heterogeneity in the environment of the complexes in the film. The decays fit well to two exponents (see Fig. S1.15†), from which amplitude-weighted average lifetimes of 3200 and 1200 µs are estimated for Pt1 and Pt2, respectively. These values are of a similar order of magnitude to those at 77 K, confirming that the incorporation of the compounds into the film leads to an environment that is sufficiently rigid to greatly attenuate non-radiative decay processes. On the other hand, even in the films, the emission is very efficiently quenched by oxygen. The decay kinetics in air-equilibrated vs. inert atmosphere conditions are compared in Fig. S1.15,† and average lifetimes of around 80 µs are obtained for the films in air.

Finally, the CPL responses of both complexes were also examined in PMMA films at room temperature with 2 wt% emitter concentration. The compounds were excited at 313 nm, and the samples were measured using an in-line geometry for excitation and emission collection, while the excitation light was depolarized using a bundle of optical fibers. The (*P*) and (*M*) enantiomers of Pt1 show signals of opposite sign, similar to those for CPL at low temperature (Fig. 4d), with $\lambda_{max}$ at 520 nm and $g_{lum}$ of the order of $10^{-3}$. However, for Pt2, the $g_{lum}$ values were so small that they could not be determined. Note that while for Pt2 the CPL signs remain unchanged (+ for (*M*) and − for (*P*)), for Pt1 they have been inverted when going from room to low temperature, but they are the same in PMMA as at low temperature, thus again highlighting the influence of the environment.

## Conclusions

In summary, we have successfully synthesized two novel, chiral helicene-NHC-based platinum(u) complexes (Pt1 and Pt2, bearing acac and dbm ligands, respectively), and studied in detail their photophysical and chiroptical properties. They exhibit long-lived phosphorescence with moderate quantum yields. Overall, the helicenic backbone in the N-heterocyclic carbene ligand allowed us to introduce chirality within the structure, generating strong chiroptical responses (intense electronic circular dichroism and circularly polarized phosphorescence). Complex Pt1 was found to exhibit strong CPL response both in solution ($g_{lum}$ of the order of $10^{-2}$ at low temperature and around $10^{-3}$ at room temperature) and in the solid state ($g_{lum}$ of the order of $10^{-3}$ in thin films at room temperature). Theoretical analysis enabled the different beha-
viors of Pt1 and Pt2 to be accounted for in terms of structural and electronic origins. Compared to the platinum(n) complexes already reported in the literature, thanks to the presence of the helicenic moiety, we observed one of the strongest circularly polarized luminescence glum (0.013 at low temperature).⁷ª
In addition, the steric protection imparted by the helicene allowed to study, for the very first time, the photophysics of square-planar cyclometalated NHC-Pt complexes in solution. Finally, the CPL measurements in solution allowed us to clearly observe the vibronic structure. Our further efforts are directed towards developments of chiral supramolecular assemblies of helical systems displaying Pt-Pt interactions for amplifying the circularly polarized phosphorescence.²⁴

## Author contributions

Conceptualization, formal analysis, validation, resources, writing - review & editing: J. C., M. S.-H., S. C. J. M., J. A. G. W.; investigation: D. K. (synthesis, characterization, computations), N. d. R. (synthesis, characterization), M. C. (X-ray structure analysis), N. V. (chiral HPLC separations), S. C. J. M. (solid-state CPL), E. V. P. & J. A. G. W. (photophysics in solution and films), M. S.-H. (computations); methodology: D. K., M. S.-H.; writing - original draft: D. K., N. d. R., J. C.; visualization: D. K., M. S.-H., S. C. J. M., E. V. P.; supervision: J. C., J. A. G. W., M. S.-H.; funding acquisition: J. C., E. V. P.; project administration: J. C.

## Conflicts of interest

There are no conflicts to declare.

## Acknowledgements

We acknowledge the Ministère de l'Éducation Nationale, de la Recherche et de la Technologie, the Centre National de la Recherche Scientifique (CNRS), and the European Commission Research Executive Agency (grant agreement number: 859752—HEL4CHIROLED—H2020-MSCA-ITN-2019) for financial support. The computational part of the study was supported by PL-Grid Infrastructure and the ACC Cyfronet AGH in Krakow, Poland. E. V. P. and J. A. G. W. acknowledge the EPSRC grant ref: EP/S012788/1.

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