# Vulvovaginal rhabdomyosarcoma

INSERM

## Source

INSERM. (1999). Orphanet: an online rare disease and orphan drug data base.

Vulvovaginal rhabdomyosarcoma. ORPHA:206492

Vulvovaginal rhabdomyosarcoma is a rare vulvovaginal tumour, a highly malignant soft tissue sarcoma composed of cells with round to oval or spindle-shaped nuclei and eosinophilic cytoplasm that may show differentiation towards striated muscle cells. It usually affects children and presents with a vulvar or vaginal mass that may be polypoid or grape-like (embryonal subtype) and associated with bleeding and ulceration.