# OPRM1 wt Allele

National Cancer Institute

## Source

National Cancer Institute. OPRM1 wt Allele. NCI Thesaurus. Code C118984.

Human OPRM1 wild-type allele is located within 6q24-q25 and is approximately 236 kb in length. This allele, which encodes Mu-type opioid receptor protein, is involved in opioid binding and signaling. A point mutation in the gene may be associated with addiction to opioids and alcohol, and variations in pain sensitivity