# Corrigendum: Myelination Increases the Spatial Extent of Analog-Digital Modulation of Synaptic Transmission: A Modeling Study

Mickaël Zbili, Dominique Debanne

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Mickaël Zbili, Dominique Debanne. Corrigendum: Myelination Increases the Spatial Extent of Analog-Digital Modulation of Synaptic Transmission: A Modeling Study. Frontiers in Cellular Neuroscience, 2020, 14, 10.3389/fncel.2020.00099. hal-03139013

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# Corrigendum: Myelination Increases the Spatial Extent of Analog-Digital Modulation of Synaptic Transmission: A Modeling Study

Mickaël Zbili<fnref n="1" />,<fnref n="2" />* and Dominique Debanne<fnref n="2" />*

OPEN ACCESS

**Edited and reviewed by:**
Josef Bischofberger,
University of Basel, Switzerland

*Correspondence:
Mickaël Zbili
zbili.mickael@gmail.com
Dominique Debanne
dominique.debanne@inserm.fr

**Specialty section:**
This article was submitted to
Cellular Neurophysiology,
a section of the journal
Frontiers in Cellular Neuroscience

**Received:** 23 March 2020

**Accepted:** 31 March 2020

**Published:** 04 May 2020

**Citation:**
Zbili M and Debanne D (2020)
Corrigendum: Myelination Increases
the Spatial Extent of Analog-Digital
Modulation of Synaptic Transmission:
A Modeling Study.
Front. Cell. Neurosci. 14:99.
doi: 10.3389/fncel.2020.00099

**Keywords:** myelin, axon, axonal space constant, analog digital facilitation, spike shape, ion channels, axonal length constant

## A Corrigendum on

### Myelination Increases the Spatial Extent of Analog-Digital Modulation of Synaptic Transmission: A Modeling Study

by Zbili, M., and Debanne, D. (2020). Front. Cell. Neurosci. 14:40. doi: 10.3389/fncel.2020.00040

In the original article, there was an error in the equation $W = A * Q_{Ca}^{2+}$ describing how we computed the synaptic strength from the calcium charge in the presynaptic terminals. Actually, we used the following equation in the model: $W = A * (Q_{Ca}^{2+})^{2.5}$. In consequence, a correction has been made to the Materials and Methods section, subsection Postsynaptic Responses, first paragraph:

"To obtain the postsynaptic responses, we used Alpha Synapse Point Processes from Neuron 7.6 inserted into postsynaptic cells. The weights of the synapses were calculated using the charge of the spike-evoked $Ca^{2+}$ entry in the presynaptic sites with the following power law:

$$W = A * (Q_{Ca}^{2+})^{2.5}$$

where W is the synaptic weight, A is a scaling factor and $Q_{Ca}$ is the charge of the spike-evoked $Ca^{2+}$ current (Scott et al., 2008). Therefore, an increase in the $Ca^{2+}$ entry produced by an increase in presynaptic spike amplitude or duration led to an increase in the postsynaptic response amplitude."

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

<footnote n="1">¹Lyon Neuroscience Research Center, INSERM U1028-CNRS UMR5292-Université Claude Bernard Lyon1, Lyon, France,</footnote>

<footnote n="2">²UNIS UMR 1072 INSERM, AMU, Marseille, France</footnote>
REFERENCES

Scott, R., Ruiz, A., Henneberger, C., Kullmann, D. M., and Rusakov, D. A. (2008). Analog modulation of mossy fiber transmission is uncoupled from changes in presynaptic Ca2+. J. Neurosci. 28, 7765-7773. doi: 10.1523/JNEUROSCI.1296-08.2008

Copyright © 2020 Zbili and Debanne. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.