# TFF1 wt Allele

National Cancer Institute

## Source

National Cancer Institute. TFF1 wt Allele. NCI Thesaurus. Code C52116.

Human TFF1 wild-type allele is located in the vicinity of 21q23.1 and is approximately 4 kb in length. This allele, which encodes trefoil factor 1 protein, is involved in gastrointestinal mucosa stabilization. Wild type allele dysfunction, including altered expression, deletion, and/or mutation, is observed frequently in human gastric carcinomas.