151. Tolia V, Lin CH, Kuhns LR. Gastric emptying using three different formulas in infants with gastroesophageal reflux. *J Pediatr Gastroenterol Nutr.* (1992) 15:297-301. doi: 10.1097/00005176-199210000-00011

152. Abell TL, Bernstein RK, Cutts T, Farrugia G, Forster J, Hasler WL, et al. Treatment of gastroparesis: a multidisciplinary clinical review. *Neurogastroenterol Motil.* (2006) 18:263-83. doi: 10.1111/j.1365-2982.2006.00760.x

153. Tabbers MM, DiLorenzo C, Berger MY, Faure C, Langendam MW, Nurko S, et al. Evaluation and treatment of functional constipation in infants and children: evidence-based recommendations from ESPGHAN and NASPGHAN. *J Pediatr Gastroenterol Nutr.* (2014) 58:258-74. doi: 10.1097/MPG.00000000000000266

154. Hron B, Fishman E, Lurie M, Clarke T, Chin Z, Hester L, et al. Health outcomes and quality of life indices of children receiving Blenderized feeds via enteral tube. *J Pediatr.* (2019) 211:139-145.e1. doi: 10.1016/j.jpeds.2019.04.023

155. Batsis ID, Davis L, Prichett L, Wu L, Shores D, Au Yeung K, et al. Efficacy and tolerance of blended diets in children receiving gastrostomy feeds. *Nutr Clin Pract.* (2020) 35:282-8. doi: 10.1002/ncp.10406

156. Gallagher K, Flint A, Mouzaki M, Carpenter A, Haliburton B, Bannister L, et al. Blenderized enteral nutrition diet study: feasibility, clinical, and microbiome outcomes of providing Blenderized feeds through a gastric tube in a medically complex pediatric population. *JPEN J Parenter Enteral Nutr.* (2018) 42:1046-60. doi: 10.1002/jpen.10499

157. Kiela PR, Ghishan FK. Physiology of intestinal absorption and secretion. *Best Pract Res Clin Gastroenterol.* (2016) 30:145-59. doi: 10.1016/j.bpg.2016.02.007

158. Sharma R, Williams AN, Zaw W. Timing of gastrostomy insertion in children with a neurodisability: a cross-sectional study of early versus late intervention. *BMJ Open.* (2012) 2:bmjopen-2012-001793. doi: 10.1136/bmjopen-2012-001793

159. Romano C, Pallio S, Cucinotta U, Accorsi P, Dipasquale V. Fibers in pediatric functional gastrointestinal disorders. Practical considerations from clinical cases. Expert rev. Gastroenterol Hepatol. (2021) 15:583-7. doi: 10.1080/17474124.2021.1884543

160. Maher T, Clegg ME. Dietary lipids with potential to affect satiety: mechanisms and evidence. *Crit Rev Food Sci Nutr.* (2019) 59:1619-44. doi: 10.1080/10408398.2017.1423277

161. Audiffred-González I, Morfin-Maciel BM, García-Juárez RJ, Simón-Gómez C, Flores-Fuentes M. Cow's milk protein allergy in disability children. *Rev Alerg Mex.* (2013) 60:145-51.

162. Savage K, Kritas S, Schwarzer A, Davidson G, Omari T. Whey- vs casein-based enteral formula and gastrointestinal function in children with cerebral palsy. *JPEN J Parenter Enteral Nutr.* (2012) 36:118S-23S. doi: 10.1177/0148607111428139

163. Meyer R, Foong R-XM, Thapar N, Kritas S, Shah N. Systematic review of the impact of feed protein type and degree of hydrolysis on gastric emptying in children. *BMC Gastroenterol.* (2015) 15:137. doi: 10.1186/s12876-015-0369-0

164. Dipasquale V, Catena MA, Cardile S, Romano C. Standard polymeric formula tube feeding in neurologically impaired children: a five-year retrospective study. *Nutrients.* (2018) 10:684. doi: 10.3390/nu10060684

165. Stavroulakis T, McDermott CJ. Enteral feeding in neurological disorders. *Pract Neurol.* (2016) 16:352-61. doi: 10.1136/practneurol-2016-001408

166. Dipasquale V, Aumar M, Ley D, Antoine M, Romano C, Gottrand F. Tube feeding in neurologically disabled children: hot topics and new directions. *Nutrients.* (2022) 14:3831. doi: 10.3390/nu14183831

167. Orel A, Homan M, Blagus R, Benedik E, Orel R, Fidler MN. Nutrition of patients with severe neurologic impairment. *Radiol Oncol.* (2017) 52:83-9. doi: 10.1515/raon-2017-0060

168. Dipasquale V, Diamanti A, Trovato CM, Elia D, Romano C. Real food in enteral nutrition for chronically ill children: overview and practical clinical cases. *Curr Med Res Opin.* (2022) 38:831-5. doi: 10.1080/03007995.2022.2052514

169. Axelrod CH, Saps M. The role of Fiber in the treatment of functional gastrointestinal disorders in children. *Nutrients.* (2018) 10:1650. doi: 10.3390/nu10111650

170. Yang J, Wang H-P, Zhou L, Xu C-F. Effect of dietary fiber on constipation: a meta analysis. *World J Gastroenterol.* (2012) 18:7378-83. doi: 10.3748/wjg.v18.i48.7378

171. Chandrasekar N, Dehlsen K, Leach ST, Krishnan U. Blenderised tube feeds vs. commercial formula: which is better for gastrostomy-fed children? *Nutrients.* (2022) 14:3139. doi: 10.3390/nu14153139

172. Trollip A, Lindeback R, Banerjee K. Parental perspectives on Blenderized tube feeds for children requiring supplemental nutrition. *Nutr Clin Pract.* (2020) 35:471-8. doi: 10.1002/ncp.10368

173. Blumenstein I, Shastri YM, Stein J. Gastroenteric tube feeding: techniques, problems and solutions. *World J Gastroenterol.* (2014) 20:8505-24. doi: 10.3748/wjg.v20.i26.8505

174. Krom H, de Winter JP, Kindermann A. Development, prevention, and treatment of feeding tube dependency. *Eur J Pediatr.* (2017) 176:683-8. doi: 10.1007/s00431-017-2908-x

175. O'Connor G, Watson M, Van Der Linde M, Bonner RS, Hopkins J, Saduera S. Monitor gastrointestinal tolerance in children who have switched to an "enteral formula with food-derived ingredients": a national, multicenter retrospective chart review (RICIMIX study). *Nutr Clin Pract.* (2022) 37:929-34. doi: 10.1002/ncp.10812

176. Verduc E, Di Profio E, Corsello A, Scatigno L, Fiore G, Bosetti A, et al. Which Milk during the second year of life: a personalized choice for a healthy future? *Nutrients.* (2021) 13:3412. doi: 10.3390/nu13103412

177. Jaffe N, Ball LJ, Evans S. Feeding and nutrition in the pediatric leukodystrophy patient. *Curr Probl Pediatr Adolesc Health Care.* (2023) 53:101350. doi: 10.1016/j.cppeds.2022.101350

178. Selimoglu MA, Kansu A, Aydogdu S, Sarioglu AA, Erdogan S, Dalgic B, et al. Nutritional support in malnourished children with compromised gastrointestinal function: utility of peptide-based enteral therapy. *Front Pediatr.* (2021) 9:9. doi: 10.3389/fped.2021.610275

179. Mordekar SR, Velayudhan M, Campbell DI. Feed-induced Dystonias in children with severe central nervous system disorders. *J Pediatr Gastroenterol Nutr.* (2017) 65:343-5. doi: 10.1097/MPG.00000000000001543

180. Tighe MP, Afzal NA, Bevan A, Beattie RM. Current pharmacological management of gastro-esophageal reflux in children: an evidence-based systematic review. *Paediatr Drugs.* (2009) 11:185-202. doi: 10.2165/00148581-200911030-00004

181. Candy D, Belsey J. Macrogol (polyethylene glycol) laxatives in children with functional constipation and faecal impaction: a systematic review. *Arch Dis Child.* (2009) 94:156-60. doi: 10.1136/adc.2007.128769

182. Koppen IJN, Lammers LA, Benninga MA, Tabbers MM. Management of Functional Constipation in children: therapy in practice. *Paediatr Drugs.* (2015) 17:349-60. doi: 10.1007/s40272-015-0142-4

183. Waseem S, Moshiree B, Draganov PV. Gastroparesis: current diagnostic challenges and management considerations. *World J Gastroenterol.* (2009) 15:25-37. doi: 10.3748/wjg.15.25

184. Winter HS, Di Lorenzo C, Benninga MA, Gilger MA, Kearns GL, Hyman PE, et al. Oral prucalopride in children with functional constipation. *J Pediatr Gastroenterol Nutr.* (2013) 57:197-203. doi: 10.1097/MPG.0b013e318292f9ea

185. Canziani BC, Uestuener P, Fossali EF, Lava SAG, Bianchetti MG, Agostoni C, et al. Clinical practice: nausea and vomiting in acute gastroenteritis: physiopathology and management. *Eur J Pediatr.* (2018) 177:1-5. doi: 10.1007/s00431-017-3006-9

186. Ye JH, Ponnudurai R, Schaefer R. Ondansetron: a selective 5-HT(3) receptor antagonist and its applications in CNS-related disorders. *CNS Drug Rev.* (2001) 7:199-213. doi: 10.1111/j.1527-3458.2001.tb00195.x

187. Basu S, Smith S. Macrolides for the prevention and treatment of feeding intolerance in preterm low birth weight infants: a systematic review and meta-analysis. *Eur J Pediatr.* (2021) 180:353-78. doi: 10.1007/s00431-020-03814-1

188. Kim T-S, Lee J-W, Kim M-J, Park Y-S, Lee D-H, Chung N-G, et al. Acute colonic pseudo-obstruction in postchemotherapy complication of brain tumor treated with neostigmine. *J Pediatr Hematol Oncol.* (2007) 29:420-2. doi: 10.1097/MPH.0b013e318063ef4b

189. O'Dea CJ, Brookes JH, Wattchow DA. The efficacy of treatment of patients with severe constipation or recurrent pseudo-obstruction with pyridostigmine. *Color Dis.* (2010) 12:540-8. doi: 10.1111/j.1463-1318.2009.01838.x

190. Manini ML, Camilleri M, Grothe R, Di Lorenzo C. Application of Pyridostigmine in pediatric gastrointestinal motility disorders: a case series. *Paediatr Drugs.* (2018) 20:173-80. doi: 10.1007/s40272-017-0277-6

191. Koivusalo AI, Pakarinen MP, Rintala RJ. Botox injection treatment for anal outlet obstruction in patients with internal anal sphincter achalasia and Hirschsprung's disease. *Pediatr Surg Int.* (2009) 25:873-6. doi: 10.1007/s00383-009-2438-3

192. Ge S, Mendley SR, Gerhart JG, Melloni C, Hornik CP, Sullivan JE, et al. Population pharmacokinetics of metoclopramide in infants, children, and adolescents. *Clin Transl Sci.* (2020) 13:1189-98. doi: 10.1111/cts.12803

193. Gmora S, Poenaru D, Tsai E. Neostigmine for the treatment of pediatric acute colonic pseudo-obstruction. *J Pediatr Surg.* (2002) 37:E28. doi: 10.1053/jpsu.2002.35438

194. Nardo GD, Viscogliosi F, Esposito F, Stanghellini V, Villa MP, Parisi P, et al. Pyridostigmine in pediatric intestinal Pseudo-obstruction: case report of a 2-year old girl and literature review. *J Neurogastroenterol Motil.* (2019) 25:508. doi: 10.5056/jnm19078

195. Curry JI, Lander TD, Stringer MD. Review article: erythromycin as a prokinetic agent in infants and children. *Aliment Pharmacol Ther.* (2001) 15:595-603. doi: 10.1046/j.1365-2036.2001.00964.x

196. Bonvanie IJ, Weghorst AA, Holtman GA, Russchen HA, Fickweiler F, Verkade HJ, et al. Oral ondansetron for paediatric gastroenteritis in primary care: a randomised controlled trial. *Br J Gen Pract.* (2021) 71:e728-35. doi: 10.3399/BJGP.2021.0211

197. Rodriguez L, Diaz J, Nurko S. Safety and efficacy of cyproheptadine for treating dyspeptic symptoms in children. *J Pediatr.* (2013) 163:261-7. doi: 10.1016/j.jpeds.2012.12.096

198. Chiusolo F, Capriati T, Erba I, Bianchi R, Ciofi Degli Atti ML, Picardo S, et al. Management of Enteral Nutrition in the pediatric intensive care unit: Prokinetic effects of amoxicillin/Clavulanate in real life conditions. *Pediatr Gastroenterol Hepatol Nutr.* (2020) 23:521-30. doi: 10.5223/pghn.2020.23.6.521

199. Tillman EM, Smetana KS, Bantu L, Buckley MG. Pharmacologic treatment for pediatric Gastroparesis: a review of the literature. *J Pediatr Pharmacol Ther.* (2016) 21:120-32. doi: 10.5863/1551-6776-21.2.120
151. Tolia V, Lin CH, Kuhns LR. Gastric emptying using three different formulas in infants with gastroesophageal reflux. *J Pediatr Gastroenterol Nutr.* (1992) 15:297-301. doi: 10.1097/00005176-199210000-00011

152. Abell TL, Bernstein RK, Cutts T, Farrugia G, Forster J, Hasler WL, et al. Treatment of gastroparesis: a multidisciplinary clinical review. *Neurogastroenterol Motil.* (2006) 18:263-83. doi: 10.1111/j.1365-2982.2006.00760.x

153. Tabbers MM, DiLorenzo C, Berger MY, Faure C, Langendam MW, Nurko S, et al. Evaluation and treatment of functional constipation in infants and children: evidence-based recommendations from ESPGHAN and NASPGHAN. *J Pediatr Gastroenterol Nutr.* (2014) 58:258-74. doi: 10.1097/MPG.00000000000000266

154. Hron B, Fishman E, Lurie M, Clarke T, Chin Z, Hester L, et al. Health outcomes and quality of life indices of children receiving Blenderized feeds via enteral tube. *J Pediatr.* (2019) 211:139-145.e1. doi: 10.1016/j.jpeds.2019.04.023

155. Batsis ID, Davis L, Prichett L, Wu L, Shores D, Au Yeung K, et al. Efficacy and tolerance of blended diets in children receiving gastrostomy feeds. *Nutr Clin Pract.* (2020) 35:282-8. doi: 10.1002/ncp.10406

156. Gallagher K, Flint A, Mouzaki M, Carpenter A, Haliburton B, Bannister L, et al. Blenderized enteral nutrition diet study: feasibility, clinical, and microbiome outcomes of providing Blenderized feeds through a gastric tube in a medically complex pediatric population. *JPEN J Parenter Enteral Nutr.* (2018) 42:1046-60. doi: 10.1002/jpen.10499

157. Kiela PR, Ghishan FK. Physiology of intestinal absorption and secretion. *Best Pract Res Clin Gastroenterol.* (2016) 30:145-59. doi: 10.1016/j.bpg.2016.02.007

158. Sharma R, Williams AN, Zaw W. Timing of gastrostomy insertion in children with a neurodisability: a cross-sectional study of early versus late intervention. *BMJ Open.* (2012) 2:bmjopen-2012-001793. doi: 10.1136/bmjopen-2012-001793

159. Romano C, Pallio S, Cucinotta U, Accorsi P, Dipasquale V. Fibers in pediatric functional gastrointestinal disorders. Practical considerations from clinical cases. Expert rev. Gastroenterol Hepatol. (2021) 15:583-7. doi: 10.1080/17474124.2021.1884543

160. Maher T, Clegg ME. Dietary lipids with potential to affect satiety: mechanisms and evidence. *Crit Rev Food Sci Nutr.* (2019) 59:1619-44. doi: 10.1080/10408398.2017.1423277

161. Audiffred-González I, Morfin-Maciel BM, García-Juárez RJ, Simón-Gómez C, Flores-Fuentes M. Cow's milk protein allergy in disability children. *Rev Alerg Mex.* (2013) 60:145-51.

162. Savage K, Kritas S, Schwarzer A, Davidson G, Omari T. Whey- vs casein-based enteral formula and gastrointestinal function in children with cerebral palsy. *JPEN J Parenter Enteral Nutr.* (2012) 36:118S-23S. doi: 10.1177/0148607111428139

163. Meyer R, Foong R-XM, Thapar N, Kritas S, Shah N. Systematic review of the impact of feed protein type and degree of hydrolysis on gastric emptying in children. *BMC Gastroenterol.* (2015) 15:137. doi: 10.1186/s12876-015-0369-0

164. Dipasquale V, Catena MA, Cardile S, Romano C. Standard polymeric formula tube feeding in neurologically impaired children: a five-year retrospective study. *Nutrients.* (2018) 10:684. doi: 10.3390/nu10060684

165. Stavroulakis T, McDermott CJ. Enteral feeding in neurological disorders. *Pract Neurol.* (2016) 16:352-61. doi: 10.1136/practneurol-2016-001408

166. Dipasquale V, Aumar M, Ley D, Antoine M, Romano C, Gottrand F. Tube feeding in neurologically disabled children: hot topics and new directions. *Nutrients.* (2022) 14:3831. doi: 10.3390/nu14183831

167. Orel A, Homan M, Blagus R, Benedik E, Orel R, Fidler MN. Nutrition of patients with severe neurologic impairment. *Radiol Oncol.* (2017) 52:83-9. doi: 10.1515/raon-2017-0060

168. Dipasquale V, Diamanti A, Trovato CM, Elia D, Romano C. Real food in enteral nutrition for chronically ill children: overview and practical clinical cases. *Curr Med Res Opin.* (2022) 38:831-5. doi: 10.1080/03007995.2022.2052514

169. Axelrod CH, Saps M. The role of Fiber in the treatment of functional gastrointestinal disorders in children. *Nutrients.* (2018) 10:1650. doi: 10.3390/nu10111650

170. Yang J, Wang H-P, Zhou L, Xu C-F. Effect of dietary fiber on constipation: a meta analysis. *World J Gastroenterol.* (2012) 18:7378-83. doi: 10.3748/wjg.v18.i48.7378

171. Chandrasekar N, Dehlsen K, Leach ST, Krishnan U. Blenderised tube feeds vs. commercial formula: which is better for gastrostomy-fed children? *Nutrients.* (2022) 14:3139. doi: 10.3390/nu14153139

172. Trollip A, Lindeback R, Banerjee K. Parental perspectives on Blenderized tube feeds for children requiring supplemental nutrition. *Nutr Clin Pract.* (2020) 35:471-8. doi: 10.1002/ncp.10368

173. Blumenstein I, Shastri YM, Stein J. Gastroenteric tube feeding: techniques, problems and solutions. *World J Gastroenterol.* (2014) 20:8505-24. doi: 10.3748/wjg.v20.i26.8505

174. Krom H, de Winter JP, Kindermann A. Development, prevention, and treatment of feeding tube dependency. *Eur J Pediatr.* (2017) 176:683-8. doi: 10.1007/s00431-017-2908-x

175. O'Connor G, Watson M, Van Der Linde M, Bonner RS, Hopkins J, Saduera S. Monitor gastrointestinal tolerance in children who have switched to an "enteral formula with food-derived ingredients": a national, multicenter retrospective chart review (RICIMIX study). *Nutr Clin Pract.* (2022) 37:929-34. doi: 10.1002/ncp.10812

176. Verduci E, Di Profio E, Corsello A, Scatigno L, Fiore G, Bosetti A, et al. Which Milk during the second year of life: a personalized choice for a healthy future? *Nutrients.* (2021) 13:3412. doi: 10.3390/nu13103412

177. Jaffe N, Ball LJ, Evans S. Feeding and nutrition in the pediatric leukodystrophy patient. *Curr Probl Pediatr Adolesc Health Care.* (2023) 53:101350. doi: 10.1016/j.cppeds.2022.101350

178. Selimoglu MA, Kansu A, Aydogdu S, Sarioglu AA, Erdogan S, Dalcıg B, et al. Nutritional support in malnourished children with compromised gastrointestinal function: utility of peptide-based enteral therapy. *Front Pediatr.* (2021) 9:9. doi: 10.3389/fped.2021.610275

179. Mordekar SR, Velayudhan M, Campbell DI. Feed-induced Dystonias in children with severe central nervous system disorders. *J Pediatr Gastroenterol Nutr.* (2017) 65:343-5. doi: 10.1097/MPG.00000000000001543

180. Tighe MP, Afzal NA, Bevan A, Beattie RM. Current pharmacological management of gastro-esophageal reflux in children: an evidence-based systematic review. *Paediatr Drugs.* (2009) 11:185-202. doi: 10.2165/00148581-200911030-00004

181. Candy D, Belsey J. Macrogol (polyethylene glycol) laxatives in children with functional constipation and faecal impaction: a systematic review. *Arch Dis Child.* (2009) 94:156-60. doi: 10.1136/adc.2007.128769

182. Koppen IJN, Lammers LA, Benninga MA, Tabbers MM. Management of Functional Constipation in children: therapy in practice. *Paediatr Drugs.* (2015) 17:349-60. doi: 10.1007/s40272-015-0142-4

183. Waseem S, Moshiree B, Draganov PV. Gastroparesis: current diagnostic challenges and management considerations. *World J Gastroenterol.* (2009) 15:25-37. doi: 10.3748/wjg.15.25

184. Winter HS, Di Lorenzo C, Benninga MA, Gilger MA, Kearns GL, Hyman PE, et al. Oral prucalopride in children with functional constipation. *J Pediatr Gastroenterol Nutr.* (2013) 57:197-203. doi: 10.1097/MPG.0b013e318292f9ea

185. Canziani BC, Uestuener P, Fossali EF, Lava SAG, Bianchetti MG, Agostoni C, et al. Clinical practice: nausea and vomiting in acute gastroenteritis: physiopathology and management. *Eur J Pediatr.* (2018) 177:1-5. doi: 10.1007/s00431-017-3006-9

186. Ye JH, Ponnudurai R, Schaefer R. Ondansetron: a selective 5-HT(3) receptor antagonist and its applications in CNS-related disorders. *CNS Drug Rev.* (2001) 7:199-213. doi: 10.1111/j.1527-3458.2001.tb00195.x

187. Basu S, Smith S. Macrolides for the prevention and treatment of feeding intolerance in preterm low birth weight infants: a systematic review and meta-analysis. *Eur J Pediatr.* (2021) 180:353-78. doi: 10.1007/s00431-020-03814-1

188. Kim T-S, Lee J-W, Kim M-J, Park Y-S, Lee D-H, Chung N-G, et al. Acute colonic pseudo-obstruction in postchemotherapy complication of brain tumor treated with neostigmine. *J Pediatr Hematol Oncol.* (2007) 29:420-2. doi: 10.1097/MPH.0b013e318063ef4b

189. O'Dea CJ, Brookes JH, Wattchow DA. The efficacy of treatment of patients with severe constipation or recurrent pseudo-obstruction with pyridostigmine. *Color Dis.* (2010) 12:540-8. doi: 10.1111/j.1463-1318.2009.01838.x

190. Manini ML, Camilleri M, Grothe R, Di Lorenzo C. Application of Pyridostigmine in pediatric gastrointestinal motility disorders: a case series. *Paediatr Drugs.* (2018) 20:173-80. doi: 10.1007/s40272-017-0277-6

191. Koivusalo AI, Pakarinen MP, Rintala RJ. Botox injection treatment for anal outlet obstruction in patients with internal anal sphincter achalasia and Hirschsprung's disease. *Pediatr Surg Int.* (2009) 25:873-6. doi: 10.1007/s00383-009-2438-3

192. Ge S, Mendley SR, Gerhart JG, Melloni C, Hornik CP, Sullivan JE, et al. Population pharmacokinetics of metoclopramide in infants, children, and adolescents. *Clin Transl Sci.* (2020) 13:1189-98. doi: 10.1111/cts.12803

193. Gmora S, Poenaru D, Tsai E. Neostigmine for the treatment of pediatric acute colonic pseudo-obstruction. *J Pediatr Surg.* (2002) 37:E28. doi: 10.1053/jpsu.2002.35438

194. Nardo GD, Viscogliosi F, Esposito F, Stanghellini V, Villa MP, Parisi P, et al. Pyridostigmine in pediatric intestinal Pseudo-obstruction: case report of a 2-year old girl and literature review. *J Neurogastroenterol Motil.* (2019) 25:508. doi: 10.5056/jnm19078

195. Curry JI, Lander TD, Stringer MD. Review article: erythromycin as a prokinetic agent in infants and children. *Aliment Pharmacol Ther.* (2001) 15:595-603. doi: 10.1046/j.1365-2036.2001.00964.x

196. Bonvanie IJ, Weghorst AA, Holtman GA, Russchen HA, Fickweiler F, Verkade HJ, et al. Oral ondansetron for paediatric gastroenteritis in primary care: a randomised controlled trial. *Br J Gen Pract.* (2021) 71:e728-35. doi: 10.3399/BJGP.2021.02111

197. Rodriguez L, Diaz J, Nurko S. Safety and efficacy of cyproheptadine for treating dyspeptic symptoms in children. *J Pediatr.* (2013) 163:261-7. doi: 10.1016/j.jpeds.2012.12.096

198. Chiusolo F, Capriati T, Erba I, Bianchi R, Ciofi Degli Atti ML, Picardo S, et al. Management of Enteral Nutrition in the pediatric intensive care unit: Prokinetic effects of amoxicillin/Clavulanate in real life conditions. *Pediatr Gastroenterol Hepatol Nutr.* (2020) 23:521-30. doi: 10.5223/pghn.2020.23.6.521

199. Tillman EM, Smetana KS, Bantu L, Buckley MG. Pharmacologic treatment for pediatric Gastroparesis: a review of the literature. *J Pediatr Pharmacol Ther.* (2016) 21:120-32. doi: 10.5863/1551-6776-21.2.120