<table>
  <tr>
    <td>Epha5</td>
    <td>1.500003654</td>
    <td>0.001835602</td>
    <td>0.014784141</td>
    <td>Slc35e1</td>
    <td>0.917979686</td>
    <td>1.07E-05</td>
    <td>0.000251136</td>
  </tr>
  <tr>
    <td>Epm2aip1</td>
    <td>1.009315522</td>
    <td>1.18E-05</td>
    <td>0.000271512</td>
    <td>Slc35e3</td>
    <td>0.566307449</td>
    <td>0.004212743</td>
    <td>0.027431443</td>
  </tr>
  <tr>
    <td>Eprs</td>
    <td>0.401394794</td>
    <td>0.007072484</td>
    <td>0.040292697</td>
    <td>Slc36a1</td>
    <td>1.767894304</td>
    <td>3.31E-06</td>
    <td>9.60E-05</td>
  </tr>
  <tr>
    <td>Eps15</td>
    <td>1.16881531</td>
    <td>3.55E-07</td>
    <td>1.44E-05</td>
    <td>Slc36a4</td>
    <td>0.974969493</td>
    <td>6.31E-06</td>
    <td>0.000164912</td>
  </tr>
  <tr>
    <td>Erbb3</td>
    <td>1.045626589</td>
    <td>3.78E-07</td>
    <td>1.52E-05</td>
    <td>Slc38a10</td>
    <td>0.634241001</td>
    <td>4.57E-05</td>
    <td>0.000824144</td>
  </tr>
  <tr>
    <td>Erbb4</td>
    <td>0.991635487</td>
    <td>3.24E-07</td>
    <td>1.34E-05</td>
    <td>Slc38a2</td>
    <td>1.053912347</td>
    <td>2.71E-05</td>
    <td>0.000537345</td>
  </tr>
  <tr>
    <td>Erbin</td>
    <td>1.038952445</td>
    <td>6.98E-07</td>
    <td>2.56E-05</td>
    <td>Slc39a10</td>
    <td>0.622072676</td>
    <td>0.002560887</td>
    <td>0.18835975</td>
  </tr>
  <tr>
    <td>Erc1</td>
    <td>0.617022943</td>
    <td>0.008857642</td>
    <td>0.047499574</td>
    <td>Slc39a14</td>
    <td>0.541933563</td>
    <td>0.001089506</td>
    <td>0.010076721</td>
  </tr>
  <tr>
    <td>Erlec1</td>
    <td>1.255402354</td>
    <td>3.21E-09</td>
    <td>2.29E-07</td>
    <td>Slc39a3</td>
    <td>0.439244784</td>
    <td>0.007172694</td>
    <td>0.040740814</td>
  </tr>
  <tr>
    <td>Ermp1</td>
    <td>0.90909393</td>
    <td>0.000282051</td>
    <td>0.003499316</td>
    <td>Slc39a6</td>
    <td>0.737393025</td>
    <td>0.000264855</td>
    <td>0.003331043</td>
  </tr>
  <tr>
    <td>Ern1</td>
    <td>1.121033679</td>
    <td>7.68E-08</td>
    <td>3.79E-06</td>
    <td>Slc39a9</td>
    <td>0.901133818</td>
    <td>6.13E-06</td>
    <td>0.000160655</td>
  </tr>
  <tr>
    <td>Ero1l</td>
    <td>0.876522496</td>
    <td>6.79E-06</td>
    <td>0.000173386</td>
    <td>Slc44a1</td>
    <td>0.670698223</td>
    <td>0.002195907</td>
    <td>0.016873674</td>
  </tr>
  <tr>
    <td>Esyt2</td>
    <td>0.932633376</td>
    <td>8.97E-05</td>
    <td>0.001423031</td>
    <td>Slc44a2</td>
    <td>0.755973274</td>
    <td>5.44E-06</td>
    <td>0.000145405</td>
  </tr>
  <tr>
    <td>Etnk1</td>
    <td>1.204577297</td>
    <td>7.12E-06</td>
    <td>0.000180089</td>
    <td>Slc4a2</td>
    <td>0.46902593</td>
    <td>0.002750974</td>
    <td>0.019917538</td>
  </tr>
  <tr>
    <td>Etv5</td>
    <td>1.441569974</td>
    <td>5.98E-06</td>
    <td>0.000157549</td>
    <td>Slc5a11</td>
    <td>0.902508946</td>
    <td>0.000791273</td>
    <td>0.00781884</td>
  </tr>
  <tr>
    <td>Exoc2</td>
    <td>0.659251247</td>
    <td>0.000779024</td>
    <td>0.007722016</td>
    <td>Slc5a3</td>
    <td>1.616318766</td>
    <td>8.24E-10</td>
    <td>6.60E-08</td>
  </tr>
  <tr>
    <td>Exoc6</td>
    <td>0.644650481</td>
    <td>0.002258684</td>
    <td>0.017173587</td>
    <td>Slc6a1</td>
    <td>1.19684599</td>
    <td>2.58E-05</td>
    <td>0.000516005</td>
  </tr>
  <tr>
    <td>Exoc6b</td>
    <td>0.910406918</td>
    <td>0.000242958</td>
    <td>0.003113646</td>
    <td>Slc6a6</td>
    <td>0.628480128</td>
    <td>0.000503617</td>
    <td>0.005502813</td>
  </tr>
  <tr>
    <td>Extl2</td>
    <td>0.501909229</td>
    <td>0.006042444</td>
    <td>0.035959666</td>
    <td>Slc8a1</td>
    <td>0.624294647</td>
    <td>0.001173266</td>
    <td>0.010647265</td>
  </tr>
  <tr>
    <td>Extl3</td>
    <td>0.735428031</td>
    <td>0.000279258</td>
    <td>0.003477478</td>
    <td>Slc9a6</td>
    <td>0.812451729</td>
    <td>0.000206922</td>
    <td>0.002748105</td>
  </tr>
  <tr>
    <td>Ezh1</td>
    <td>0.803666628</td>
    <td>1.07E-05</td>
    <td>0.000251274</td>
    <td>Slc9a8</td>
    <td>0.801236964</td>
    <td>9.92E-05</td>
    <td>0.001533925</td>
  </tr>
  <tr>
    <td>F5</td>
    <td>5.016017848</td>
    <td>8.95E-05</td>
    <td>0.001423031</td>
    <td>Slco1a4</td>
    <td>3.388648171</td>
    <td>5.41E-06</td>
    <td>0.000144801</td>
  </tr>
  <tr>
    <td>Fa2h</td>
    <td>0.549843879</td>
    <td>0.00523677</td>
    <td>0.032228714</td>
    <td>Slf2</td>
    <td>1.228557213</td>
    <td>1.36E-06</td>
    <td>4.53E-05</td>
  </tr>
  <tr>
    <td>Fads1</td>
    <td>0.829684054</td>
    <td>0.001343642</td>
    <td>0.011764177</td>
    <td>Slmap</td>
    <td>0.644008001</td>
    <td>0.000715656</td>
    <td>0.007241989</td>
  </tr>
  <tr>
    <td>Fah</td>
    <td>0.428783422</td>
    <td>0.001620023</td>
    <td>0.013492932</td>
    <td>Slx4</td>
    <td>1.24751922</td>
    <td>0.003260092</td>
    <td>0.022598284</td>
  </tr>
  <tr>
    <td>Fam117b</td>
    <td>1.059544514</td>
    <td>1.16E-08</td>
    <td>7.25E-07</td>
    <td>Smad2</td>
    <td>0.609076192</td>
    <td>0.005006136</td>
    <td>0.031190172</td>
  </tr>
  <tr>
    <td>Fam120b</td>
    <td>0.483549897</td>
    <td>0.001979808</td>
    <td>0.015619496</td>
    <td>Smad3</td>
    <td>1.446119765</td>
    <td>8.41E-09</td>
    <td>5.44E-07</td>
  </tr>
  <tr>
    <td>Fam120c</td>
    <td>1.241427319</td>
    <td>1.17E-05</td>
    <td>0.00026942</td>
    <td>Smad5</td>
    <td>1.007674233</td>
    <td>9.33E-06</td>
    <td>0.000225623</td>
  </tr>
  <tr>
    <td>Fam122b</td>
    <td>0.973652308</td>
    <td>6.43E-05</td>
    <td>0.00108233</td>
    <td>Smad9</td>
    <td>1.123397312</td>
    <td>0.002164118</td>
    <td>0.16676851</td>
  </tr>
  <tr>
    <td>Fam126a</td>
    <td>0.785277123</td>
    <td>0.000436521</td>
    <td>0.004927968</td>
    <td>Smarca2</td>
    <td>0.795118525</td>
    <td>0.001563987</td>
    <td>0.013174706</td>
  </tr>
  <tr>
    <td>Fam129b</td>
    <td>0.733033483</td>
    <td>0.000403016</td>
    <td>0.004616275</td>
    <td>Smarca5</td>
    <td>0.571062702</td>
    <td>0.008904626</td>
    <td>0.047710925</td>
  </tr>
  <tr>
    <td>Fam131b</td>
    <td>0.617574993</td>
    <td>0.00644664</td>
    <td>0.037704469</td>
    <td>Smarcal1</td>
    <td>0.601809877</td>
    <td>0.000230021</td>
    <td>0.002986327</td>
  </tr>
  <tr>
    <td>Fam160b1</td>
    <td>0.793226026</td>
    <td>4.15E-06</td>
    <td>0.00011634</td>
    <td>Smarcc1</td>
    <td>0.593801167</td>
    <td>0.002395608</td>
    <td>0.017977045</td>
  </tr>
  <tr>
    <td>Fam168a</td>
    <td>0.644707734</td>
    <td>0.002725844</td>
    <td>0.019787491</td>
    <td>Smarcc2</td>
    <td>0.956262848</td>
    <td>0.003558589</td>
    <td>0.024087022</td>
  </tr>
  <tr>
    <td>Fam168b</td>
    <td>0.968492179</td>
    <td>0.008228579</td>
    <td>0.045203724</td>
    <td>Smc1a</td>
    <td>0.6097738</td>
    <td>0.00025198</td>
    <td>0.003211855</td>
  </tr>
  <tr>
    <td>Fam171a1</td>
    <td>0.741049452</td>
    <td>0.001012056</td>
    <td>0.009532089</td>
    <td>Smcr8</td>
    <td>1.178571451</td>
    <td>2.57E-05</td>
    <td>0.000513914</td>
  </tr>
  <tr>
    <td>Fam171b</td>
    <td>0.746290432</td>
    <td>9.04E-05</td>
    <td>0.001428361</td>
    <td>Smg7</td>
    <td>0.750785434</td>
    <td>0.000249542</td>
    <td>0.003187219</td>
  </tr>
  <tr>
    <td>Fam189a2</td>
    <td>0.536855416</td>
    <td>0.007576438</td>
    <td>0.042384552</td>
    <td>Smim10l1</td>
    <td>0.717386282</td>
    <td>7.53E-06</td>
    <td>0.000187401</td>
  </tr>
  <tr>
    <td>Fam20b</td>
    <td>0.791086145</td>
    <td>4.28E-06</td>
    <td>0.000119237</td>
    <td>Smim13</td>
    <td>0.933785568</td>
    <td>5.63E-07</td>
    <td>2.13E-05</td>
  </tr>
  <tr>
    <td>Fam210b</td>
    <td>0.770997438</td>
    <td>0.001333576</td>
    <td>0.011686873</td>
    <td>Smoc1</td>
    <td>1.301923794</td>
    <td>2.31E-11</td>
    <td>2.54E-09</td>
  </tr>
  <tr>
    <td>Fam219b</td>
    <td>0.539085664</td>
    <td>0.004343868</td>
    <td>0.028072525</td>
    <td>Smug1</td>
    <td>0.542296891</td>
    <td>0.001312204</td>
    <td>0.011558526</td>
  </tr>
  <tr>
    <td>Fam32a</td>
    <td>0.511710553</td>
    <td>0.000188326</td>
    <td>0.002557413</td>
    <td>Smurf1</td>
    <td>0.589930275</td>
    <td>0.004633504</td>
    <td>0.029470768</td>
  </tr>
  <tr>
    <td>Fam45a</td>
    <td>0.743503574</td>
    <td>0.00046576</td>
    <td>0.005174879</td>
    <td>Smyd3</td>
    <td>0.62767989</td>
    <td>0.001075906</td>
    <td>0.009987248</td>
  </tr>
  <tr>
    <td>Fam53b</td>
    <td>0.632155836</td>
    <td>0.000128698</td>
    <td>0.001882962</td>
    <td>Snap29</td>
    <td>0.544969989</td>
    <td>0.006521341</td>
    <td>0.03803056</td>
  </tr>
  <tr>
    <td>Fam53c</td>
    <td>0.76860034</td>
    <td>3.19E-05</td>
    <td>0.000612503</td>
    <td>Snd1</td>
    <td>0.665859761</td>
    <td>1.80E-05</td>
    <td>0.000384804</td>
  </tr>
  <tr>
    <td>Fam8a1</td>
    <td>0.901401586</td>
    <td>9.08E-05</td>
    <td>0.001432656</td>
    <td>Snn</td>
    <td>1.012860668</td>
    <td>5.43E-07</td>
    <td>2.07E-05</td>
  </tr>
  <tr>
    <td>Fam91a1</td>
    <td>1.173750986</td>
    <td>3.43E-06</td>
    <td>9.82E-05</td>
    <td>Snmp200</td>
    <td>0.739140565</td>
    <td>9.78E-05</td>
    <td>0.001516573</td>
  </tr>
  <tr>
    <td>Far1</td>
    <td>0.480765208</td>
    <td>0.008143672</td>
    <td>0.044959061</td>
    <td>Sntb1</td>
    <td>3.577255899</td>
    <td>0.001885586</td>
    <td>0.01504569</td>
  </tr>
  <tr>
    <td>Farp2</td>
    <td>0.796327211</td>
    <td>0.000209959</td>
    <td>0.002773483</td>
    <td>Snx13</td>
    <td>0.854848039</td>
    <td>3.02E-05</td>
    <td>0.000585735</td>
  </tr>
  <tr>
    <td>Fat1</td>
    <td>0.879504731</td>
    <td>0.001047636</td>
    <td>0.009808547</td>
    <td>Snx18</td>
    <td>0.585724462</td>
    <td>0.005901625</td>
    <td>0.035359245</td>
  </tr>
  <tr>
    <td>Faxc</td>
    <td>1.763936744</td>
    <td>0.001710644</td>
    <td>0.014049574</td>
    <td>Snx19</td>
    <td>0.894651315</td>
    <td>1.53E-06</td>
    <td>5.01E-05</td>
  </tr>
  <tr>
    <td>Fbln2</td>
    <td>3.573122395</td>
    <td>0.005066414</td>
    <td>0.031480063</td>
    <td>Snx25</td>
    <td>1.502080168</td>
    <td>0.00736733</td>
    <td>0.041534339</td>
  </tr>
  <tr>
    <td>Fbxl3</td>
    <td>0.541822119</td>
    <td>0.002495204</td>
    <td>0.018457389</td>
    <td>Snx30</td>
    <td>0.531535017</td>
    <td>0.000604799</td>
    <td>0.006323292</td>
  </tr>
  <tr>
    <td>Fbxo10</td>
    <td>0.978210803</td>
    <td>0.000453809</td>
    <td>0.005075953</td>
    <td>Socs4</td>
    <td>1.195282793</td>
    <td>2.08E-06</td>
    <td>6.52E-05</td>
  </tr>
  <tr>
    <td>Fbxo21</td>
    <td>0.685664199</td>
    <td>1.93E-05</td>
    <td>0.000410063</td>
    <td>Socs5</td>
    <td>0.613880754</td>
    <td>0.002319794</td>
    <td>0.017512403</td>
  </tr>
  <tr>
    <td>Fbxo32</td>
    <td>0.478326872</td>
    <td>0.002993612</td>
    <td>0.021249811</td>
    <td>Socs6</td>
    <td>0.591528664</td>
    <td>0.002259179</td>
    <td>0.017173587</td>
  </tr>
  <tr>
    <td>Fbxo34</td>
    <td>0.645459304</td>
    <td>0.000348793</td>
    <td>0.004120772</td>
    <td>Soga1</td>
    <td>0.712660674</td>
    <td>9.75E-05</td>
    <td>0.001515112</td>
  </tr>
  <tr>
    <td>Fbxo38</td>
    <td>0.866590102</td>
    <td>1.17E-06</td>
    <td>3.99E-05</td>
    <td>Sori1</td>
    <td>0.582462942</td>
    <td>0.008330268</td>
    <td>0.04558793</td>
  </tr>
  <tr>
    <td>Fbxo45</td>
    <td>1.15143936</td>
    <td>2.78E-05</td>
    <td>0.000547229</td>
    <td>Sort1</td>
    <td>1.248696844</td>
    <td>2.02E-06</td>
    <td>6.38E-05</td>
  </tr>
  <tr>
    <td>Fbxw11</td>
    <td>0.943298908</td>
    <td>1.96E-05</td>
    <td>0.00041533</td>
    <td>Sos1</td>
    <td>0.936393756</td>
    <td>0.001017629</td>
    <td>0.009579805</td>
  </tr>
  <tr>
    <td>Fcho1</td>
    <td>7.142669447</td>
    <td>1.38E-93</td>
    <td>6.52E-90</td>
    <td>Sos2</td>
    <td>0.843935432</td>
    <td>0.001346657</td>
    <td>0.011774218</td>
  </tr>
  <tr>
    <td>Fcho2</td>
    <td>0.790522498</td>
    <td>0.000157996</td>
    <td>0.002228811</td>
    <td>Sowahc</td>
    <td>0.905291469</td>
    <td>0.000304817</td>
    <td>0.00373425</td>
  </tr>
  <tr>
    <td>Fem1c</td>
    <td>0.702450188</td>
    <td>1.07E-05</td>
    <td>0.000251274</td>
    <td>Sox10</td>
    <td>0.548649904</td>
    <td>0.003222391</td>
    <td>0.022419159</td>
  </tr>
  <tr>
    <td>Fer1l5</td>
    <td>1.336359719</td>
    <td>0.001753725</td>
    <td>0.014313759</td>
    <td>Sox12</td>
    <td>0.77095447</td>
    <td>0.002242531</td>
    <td>0.017072314</td>
  </tr>
  <tr>
    <td>Fgf1</td>
    <td>1.378274167</td>
    <td>2.81E-10</td>
    <td>2.48E-08</td>
    <td>Sox13</td>
    <td>1.243153035</td>
    <td>0.002515685</td>
    <td>0.18575777</td>
  </tr>
  <tr>
    <td>Fgf7</td>
    <td>1.3568992</td>
    <td>0.00032973</td>
    <td>0.003947661</td>
    <td>Sp2</td>
    <td>0.728439706</td>
    <td>6.26E-05</td>
    <td>0.001065344</td>
  </tr>
  <tr>
    <td>Fgfr2</td>
    <td>0.693509167</td>
    <td>0.000121399</td>
    <td>0.001801898</td>
    <td>Sp3</td>
    <td>0.625110243</td>
    <td>0.001180379</td>
    <td>0.010692419</td>
  </tr>
  <tr>
    <td>Fip1l1</td>
    <td>0.801864622</td>
    <td>0.000990055</td>
    <td>0.009359735</td>
    <td>Sp4</td>
    <td>0.719454239</td>
    <td>0.002306987</td>
    <td>0.017436617</td>
  </tr>
  <tr>
    <td>Fitm2</td>
    <td>0.562890826</td>
    <td>0.008791419</td>
    <td>0.047292028</td>
    <td>Spag9</td>
    <td>1.231636623</td>
    <td>1.58E-05</td>
    <td>0.000344367</td>
  </tr>
  <tr>
    <td>Flnb</td>
    <td>1.401355197</td>
    <td>5.88E-06</td>
    <td>0.000155186</td>
    <td>Spast</td>
    <td>0.666892326</td>
    <td>0.00033191</td>
    <td>0.003965925</td>
  </tr>
</table>
<table>
  <tr>
    <td>Flt1</td>
    <td>6.974431481</td>
    <td>2.50E-06</td>
    <td>7.52E-05</td>
    <td>Spata2</td>
    <td>0.664743402</td>
    <td>4.95E-06</td>
    <td>0.000134675</td>
  </tr>
  <tr>
    <td>Flywch1</td>
    <td>0.65193857</td>
    <td>0.000238205</td>
    <td>0.003067296</td>
    <td>Spcs3</td>
    <td>0.615900138</td>
    <td>0.006544425</td>
    <td>0.038123042</td>
  </tr>
  <tr>
    <td>Fmr1</td>
    <td>0.7610213</td>
    <td>6.02E-05</td>
    <td>0.001031014</td>
    <td>Specc1l</td>
    <td>1.215356054</td>
    <td>0.00020689</td>
    <td>0.002748105</td>
  </tr>
  <tr>
    <td>Fnip2</td>
    <td>0.674644352</td>
    <td>0.001974024</td>
    <td>0.015593386</td>
    <td>Spgl11</td>
    <td>0.880989816</td>
    <td>0.001685639</td>
    <td>0.013896043</td>
  </tr>
  <tr>
    <td>Focad</td>
    <td>0.741090555</td>
    <td>0.000114335</td>
    <td>0.001714948</td>
    <td>Spin1</td>
    <td>0.621616184</td>
    <td>0.002830472</td>
    <td>0.020351622</td>
  </tr>
  <tr>
    <td>Folh1</td>
    <td>1.16327106</td>
    <td>3.84E-10</td>
    <td>3.30E-08</td>
    <td>Spin4</td>
    <td>0.88692541</td>
    <td>0.007332528</td>
    <td>0.041381055</td>
  </tr>
  <tr>
    <td>Foxd3</td>
    <td>7.529418816</td>
    <td>3.54E-05</td>
    <td>0.000666412</td>
    <td>Spock1</td>
    <td>1.433153566</td>
    <td>2.52E-05</td>
    <td>0.000506275</td>
  </tr>
  <tr>
    <td>Foxj2</td>
    <td>0.806692672</td>
    <td>4.74E-07</td>
    <td>1.84E-05</td>
    <td>Spop</td>
    <td>0.433238437</td>
    <td>0.001639396</td>
    <td>0.013597854</td>
  </tr>
  <tr>
    <td>Foxj3</td>
    <td>0.746756423</td>
    <td>3.94E-05</td>
    <td>0.00073154</td>
    <td>Sppl3</td>
    <td>0.662817983</td>
    <td>0.006295348</td>
    <td>0.037017701</td>
  </tr>
  <tr>
    <td>Foxk1</td>
    <td>0.704577526</td>
    <td>0.006047152</td>
    <td>0.035968947</td>
    <td>Spred1</td>
    <td>1.145335329</td>
    <td>0.000139934</td>
    <td>0.002019223</td>
  </tr>
  <tr>
    <td>Foxp4</td>
    <td>0.780598962</td>
    <td>0.001353004</td>
    <td>0.011802372</td>
    <td>Spryl</td>
    <td>1.059339242</td>
    <td>9.77E-05</td>
    <td>0.001516573</td>
  </tr>
  <tr>
    <td>Foxred2</td>
    <td>1.245527059</td>
    <td>0.00013538</td>
    <td>0.001963994</td>
    <td>Spta1</td>
    <td>6.505306516</td>
    <td>3.35E-05</td>
    <td>0.000638044</td>
  </tr>
  <tr>
    <td>Frmd5</td>
    <td>0.69878293</td>
    <td>1.35E-05</td>
    <td>0.00030274</td>
    <td>Spty2d1</td>
    <td>0.771819893</td>
    <td>6.95E-05</td>
    <td>0.001150673</td>
  </tr>
  <tr>
    <td>Frrs1</td>
    <td>1.355507311</td>
    <td>0.004980487</td>
    <td>0.031122695</td>
    <td>Srcin1</td>
    <td>0.565573874</td>
    <td>0.007622267</td>
    <td>0.04261571</td>
  </tr>
  <tr>
    <td>Frs2</td>
    <td>0.874380797</td>
    <td>0.000128001</td>
    <td>0.001874202</td>
    <td>Srd5a1</td>
    <td>0.473487971</td>
    <td>0.008692278</td>
    <td>0.046945752</td>
  </tr>
  <tr>
    <td>Fryl</td>
    <td>0.60294156</td>
    <td>0.005507858</td>
    <td>0.03345599</td>
    <td>Srebf1</td>
    <td>0.505215798</td>
    <td>0.008341974</td>
    <td>0.045614211</td>
  </tr>
  <tr>
    <td>Frzb</td>
    <td>3.103439052</td>
    <td>5.03E-05</td>
    <td>0.000895121</td>
    <td>Srr</td>
    <td>0.82280894</td>
    <td>0.001766664</td>
    <td>0.014400709</td>
  </tr>
  <tr>
    <td>Fubp3</td>
    <td>0.57930863</td>
    <td>0.000440306</td>
    <td>0.004959766</td>
    <td>Ss18</td>
    <td>0.786481737</td>
    <td>0.001135458</td>
    <td>0.010378898</td>
  </tr>
  <tr>
    <td>Fuca2</td>
    <td>0.885231567</td>
    <td>4.57E-05</td>
    <td>0.000824144</td>
    <td>Ss18l1</td>
    <td>0.984665301</td>
    <td>0.000263436</td>
    <td>0.003317606</td>
  </tr>
  <tr>
    <td>Furin</td>
    <td>1.01746079</td>
    <td>0.002049884</td>
    <td>0.015992143</td>
    <td>Ssh1</td>
    <td>0.676812062</td>
    <td>0.000695167</td>
    <td>0.00706112</td>
  </tr>
  <tr>
    <td>Fut9</td>
    <td>1.300964889</td>
    <td>0.005699533</td>
    <td>0.034366274</td>
    <td>Sspn</td>
    <td>0.808622308</td>
    <td>0.000232768</td>
    <td>0.003009591</td>
  </tr>
  <tr>
    <td>Fxr2</td>
    <td>0.567573806</td>
    <td>0.000622739</td>
    <td>0.06478614</td>
    <td>Ssrp1</td>
    <td>0.4918462</td>
    <td>0.005590635</td>
    <td>0.033854486</td>
  </tr>
  <tr>
    <td>Gaa</td>
    <td>0.60679906</td>
    <td>0.003704482</td>
    <td>0.024875958</td>
    <td>St3gal3</td>
    <td>0.556592051</td>
    <td>0.003517669</td>
    <td>0.023875945</td>
  </tr>
  <tr>
    <td>Gab1</td>
    <td>0.858515081</td>
    <td>4.42E-06</td>
    <td>0.000121889</td>
    <td>St6galnac3</td>
    <td>0.518948494</td>
    <td>0.003806783</td>
    <td>0.02536469</td>
  </tr>
  <tr>
    <td>Gab2</td>
    <td>1.201973989</td>
    <td>8.67E-05</td>
    <td>0.001389936</td>
    <td>Stag1</td>
    <td>0.531193277</td>
    <td>0.006140929</td>
    <td>0.036355147</td>
  </tr>
  <tr>
    <td>Gabpa</td>
    <td>0.876996494</td>
    <td>0.000136039</td>
    <td>0.001970534</td>
    <td>Stag2</td>
    <td>1.134646535</td>
    <td>5.56E-08</td>
    <td>2.85E-06</td>
  </tr>
  <tr>
    <td>Gak</td>
    <td>0.750765925</td>
    <td>0.000212635</td>
    <td>0.002801005</td>
    <td>Stam2</td>
    <td>0.76323171</td>
    <td>0.00038946</td>
    <td>0.004478674</td>
  </tr>
  <tr>
    <td>Gal3st2b</td>
    <td>4.579710444</td>
    <td>0.001478581</td>
    <td>0.012578589</td>
    <td>Stat3</td>
    <td>0.486598417</td>
    <td>0.005713529</td>
    <td>0.034428702</td>
  </tr>
  <tr>
    <td>Galnt1</td>
    <td>0.57556155</td>
    <td>0.004827078</td>
    <td>0.030427369</td>
    <td>Stau1</td>
    <td>0.630531341</td>
    <td>0.001880374</td>
    <td>0.015023127</td>
  </tr>
  <tr>
    <td>Galnt10</td>
    <td>2.643612428</td>
    <td>2.20E-44</td>
    <td>2.77E-41</td>
    <td>Stk10</td>
    <td>2.309040108</td>
    <td>7.75E-12</td>
    <td>8.99E-10</td>
  </tr>
  <tr>
    <td>Galnt11</td>
    <td>0.494922826</td>
    <td>0.000831313</td>
    <td>0.008142124</td>
    <td>Stk35</td>
    <td>0.660378373</td>
    <td>0.001180505</td>
    <td>0.010692419</td>
  </tr>
  <tr>
    <td>Galnt16</td>
    <td>0.779752688</td>
    <td>2.00E-05</td>
    <td>0.000421587</td>
    <td>Stk4</td>
    <td>0.985083606</td>
    <td>1.69E-06</td>
    <td>5.46E-05</td>
  </tr>
  <tr>
    <td>Galnt6</td>
    <td>0.693400512</td>
    <td>9.09E-05</td>
    <td>0.001432656</td>
    <td>Strn</td>
    <td>0.84262973</td>
    <td>2.43E-05</td>
    <td>0.000492873</td>
  </tr>
  <tr>
    <td>Galnt7</td>
    <td>1.099085699</td>
    <td>1.65E-08</td>
    <td>9.95E-07</td>
    <td>Stt3b</td>
    <td>0.792306396</td>
    <td>0.000530597</td>
    <td>0.005731361</td>
  </tr>
  <tr>
    <td>Gapvd1</td>
    <td>0.550886019</td>
    <td>0.009300064</td>
    <td>0.049133345</td>
    <td>Stx17</td>
    <td>0.690525604</td>
    <td>5.53E-05</td>
    <td>0.000962477</td>
  </tr>
  <tr>
    <td>Garem1</td>
    <td>0.70388897</td>
    <td>0.000545625</td>
    <td>0.005856875</td>
    <td>Stx1b</td>
    <td>1.129980085</td>
    <td>3.27E-06</td>
    <td>9.54E-05</td>
  </tr>
  <tr>
    <td>Gas2</td>
    <td>0.484991204</td>
    <td>0.006684987</td>
    <td>0.038679617</td>
    <td>Stxbp1</td>
    <td>0.682466404</td>
    <td>0.001883769</td>
    <td>0.015037537</td>
  </tr>
  <tr>
    <td>Gcc1</td>
    <td>0.59160543</td>
    <td>0.008326029</td>
    <td>0.0455807</td>
    <td>Stxbp3</td>
    <td>0.45120046</td>
    <td>0.005261785</td>
    <td>0.032335344</td>
  </tr>
  <tr>
    <td>Gcn1</td>
    <td>0.777872293</td>
    <td>3.63E-05</td>
    <td>0.00068125</td>
    <td>Suclg2</td>
    <td>1.951945239</td>
    <td>1.22E-12</td>
    <td>1.57E-10</td>
  </tr>
  <tr>
    <td>Gcnt1</td>
    <td>1.885259267</td>
    <td>0.005424298</td>
    <td>0.033108009</td>
    <td>Suco</td>
    <td>0.920267333</td>
    <td>1.02E-08</td>
    <td>6.41E-07</td>
  </tr>
  <tr>
    <td>Gdap2</td>
    <td>0.486289099</td>
    <td>0.00260024</td>
    <td>0.019095699</td>
    <td>Sufu</td>
    <td>0.676941463</td>
    <td>0.008228642</td>
    <td>0.045203724</td>
  </tr>
  <tr>
    <td>Gdpd4</td>
    <td>4.218857779</td>
    <td>0.000705209</td>
    <td>0.007151587</td>
    <td>Sulf2</td>
    <td>0.731738706</td>
    <td>7.68E-05</td>
    <td>0.001247557</td>
  </tr>
  <tr>
    <td>Gfra1</td>
    <td>0.778824225</td>
    <td>0.000747818</td>
    <td>0.00749921</td>
    <td>Sun1</td>
    <td>0.807408506</td>
    <td>0.001424193</td>
    <td>0.012214843</td>
  </tr>
  <tr>
    <td>Gid4</td>
    <td>1.011076158</td>
    <td>0.000272117</td>
    <td>0.003408768</td>
    <td>Sun2</td>
    <td>1.134020539</td>
    <td>0.000681425</td>
    <td>0.00695142</td>
  </tr>
  <tr>
    <td>Gk</td>
    <td>0.708609893</td>
    <td>0.004942483</td>
    <td>0.030905641</td>
    <td>Surf6</td>
    <td>0.560040524</td>
    <td>0.003038107</td>
    <td>0.021488736</td>
  </tr>
  <tr>
    <td>Glg1</td>
    <td>0.608831936</td>
    <td>0.006280089</td>
    <td>0.036982094</td>
    <td>Susd6</td>
    <td>0.924606107</td>
    <td>5.39E-05</td>
    <td>0.000944762</td>
  </tr>
  <tr>
    <td>Gli2</td>
    <td>2.295886612</td>
    <td>0.003215639</td>
    <td>0.022396915</td>
    <td>Suv39h1</td>
    <td>0.502005487</td>
    <td>0.006521759</td>
    <td>0.03803056</td>
  </tr>
  <tr>
    <td>Glo1</td>
    <td>0.784818797</td>
    <td>0.006003218</td>
    <td>0.035809037</td>
    <td>Sv2a</td>
    <td>0.652211032</td>
    <td>0.004865946</td>
    <td>0.030607107</td>
  </tr>
  <tr>
    <td>Glyr1</td>
    <td>0.618064482</td>
    <td>0.000765385</td>
    <td>0.007627197</td>
    <td>Svip</td>
    <td>0.939546958</td>
    <td>4.05E-05</td>
    <td>0.000747472</td>
  </tr>
  <tr>
    <td>Gna12</td>
    <td>0.65912617</td>
    <td>0.007571359</td>
    <td>0.042370488</td>
    <td>Sybu</td>
    <td>0.777082905</td>
    <td>0.000440476</td>
    <td>0.004959766</td>
  </tr>
  <tr>
    <td>Gna01</td>
    <td>0.985244499</td>
    <td>0.001159425</td>
    <td>0.010557136</td>
    <td>Sycp1</td>
    <td>8.228601025</td>
    <td>4.11E-010</td>
    <td>3.51E-08</td>
  </tr>
  <tr>
    <td>Gnb1</td>
    <td>0.868964459</td>
    <td>0.000130806</td>
    <td>0.001909367</td>
    <td>Syde2</td>
    <td>0.882575968</td>
    <td>0.007293822</td>
    <td>0.041205951</td>
  </tr>
  <tr>
    <td>Gne</td>
    <td>0.609119663</td>
    <td>0.000760806</td>
    <td>0.007605242</td>
    <td>Sympk</td>
    <td>0.495160075</td>
    <td>0.000462684</td>
    <td>0.005147804</td>
  </tr>
  <tr>
    <td>Gng12</td>
    <td>0.97309639</td>
    <td>0.00014547</td>
    <td>0.002084777</td>
    <td>Syngr3</td>
    <td>1.263290022</td>
    <td>7.51E-05</td>
    <td>0.00122424</td>
  </tr>
  <tr>
    <td>Gng7</td>
    <td>0.611753906</td>
    <td>0.000118371</td>
    <td>0.00176187</td>
    <td>Synj1</td>
    <td>0.875539053</td>
    <td>0.001068997</td>
    <td>0.0099577</td>
  </tr>
  <tr>
    <td>Gnl3l</td>
    <td>0.778274529</td>
    <td>0.000259132</td>
    <td>0.003276509</td>
    <td>Synj2</td>
    <td>0.617662922</td>
    <td>0.000783978</td>
    <td>0.007758917</td>
  </tr>
  <tr>
    <td>Gnptab</td>
    <td>1.144703091</td>
    <td>0.000386206</td>
    <td>0.004454193</td>
    <td>Synm</td>
    <td>0.729106257</td>
    <td>0.000840798</td>
    <td>0.00820951</td>
  </tr>
  <tr>
    <td>Gns</td>
    <td>0.991199453</td>
    <td>6.37E-06</td>
    <td>0.000166146</td>
    <td>Synrg</td>
    <td>0.837810064</td>
    <td>0.000944241</td>
    <td>0.009037461</td>
  </tr>
  <tr>
    <td>Golga3</td>
    <td>1.024856523</td>
    <td>0.000187733</td>
    <td>0.002554873</td>
    <td>Tacc1</td>
    <td>0.890628871</td>
    <td>2.78E-07</td>
    <td>1.18E-05</td>
  </tr>
  <tr>
    <td>Golph3</td>
    <td>0.622243834</td>
    <td>0.001948299</td>
    <td>0.015454762</td>
    <td>Taf1</td>
    <td>0.777996287</td>
    <td>2.32E-05</td>
    <td>0.000475602</td>
  </tr>
  <tr>
    <td>Gosr1</td>
    <td>0.933207416</td>
    <td>6.57E-06</td>
    <td>0.000169969</td>
    <td>Taf1b</td>
    <td>0.811337774</td>
    <td>0.006738072</td>
    <td>0.038879663</td>
  </tr>
  <tr>
    <td>Gpalpp1</td>
    <td>1.00901314</td>
    <td>8.85E-07</td>
    <td>3.14E-05</td>
    <td>Taf2</td>
    <td>0.714777902</td>
    <td>0.003601381</td>
    <td>0.02431318</td>
  </tr>
  <tr>
    <td>Gpam</td>
    <td>1.081634304</td>
    <td>1.55E-07</td>
    <td>7.01E-06</td>
    <td>Tanc1</td>
    <td>1.04378181</td>
    <td>7.06E-06</td>
    <td>0.00017917</td>
  </tr>
  <tr>
    <td>Gpatch2l</td>
    <td>0.555389941</td>
    <td>0.006080862</td>
    <td>0.036083692</td>
    <td>Tarbp1</td>
    <td>0.735045144</td>
    <td>0.000548129</td>
    <td>0.005872173</td>
  </tr>
  <tr>
    <td>Gpatch8</td>
    <td>0.721424524</td>
    <td>0.00485623</td>
    <td>0.030578722</td>
    <td>Tax1bp1</td>
    <td>0.695148064</td>
    <td>6.88E-05</td>
    <td>0.001142558</td>
  </tr>
  <tr>
    <td>Gpdl1</td>
    <td>0.742892275</td>
    <td>0.002495377</td>
    <td>0.018457389</td>
    <td>Tbc1d14</td>
    <td>0.528886224</td>
    <td>0.002540125</td>
    <td>0.018726979</td>
  </tr>
  <tr>
    <td>Gpkow</td>
    <td>0.833812999</td>
    <td>9.93E-05</td>
    <td>0.001534374</td>
    <td>Tbc1d20</td>
    <td>0.540918876</td>
    <td>0.000140543</td>
    <td>0.002021829</td>
  </tr>
  <tr>
    <td>Gpr107</td>
    <td>0.600956613</td>
    <td>0.000719066</td>
    <td>0.007265985</td>
    <td>Tbc1d22a</td>
    <td>0.557154618</td>
    <td>0.005065278</td>
    <td>0.031480063</td>
  </tr>
  <tr>
    <td>Gpr146</td>
    <td>0.597977772</td>
    <td>0.00574834</td>
    <td>0.034594354</td>
    <td>Tbc1d24</td>
    <td>0.862085649</td>
    <td>0.006386348</td>
    <td>0.037432912</td>
  </tr>
  <tr>
    <td>Gpr75</td>
    <td>2.144192764</td>
    <td>2.14E-10</td>
    <td>2.00E-08</td>
    <td>Tbc1d30</td>
    <td>1.546155197</td>
    <td>5.19E-10</td>
    <td>4.36E-08</td>
  </tr>
</table>
<table>
  <tr>
    <td>Gprasp1</td>
    <td>1.260803884</td>
    <td>0.000222743</td>
    <td>0.002905063</td>
    <td>Tbc1d5</td>
    <td>0.71881237</td>
    <td>7.18E-06</td>
    <td>0.000180996</td>
  </tr>
  <tr>
    <td>Gprasp2</td>
    <td>1.337650952</td>
    <td>0.00174942</td>
    <td>0.014290963</td>
    <td>Tbc1d9b</td>
    <td>0.713112007</td>
    <td>0.001392733</td>
    <td>0.012010479</td>
  </tr>
  <tr>
    <td>Gramd4</td>
    <td>1.081638639</td>
    <td>0.000185412</td>
    <td>0.002525099</td>
    <td>Tbccd1</td>
    <td>0.544340668</td>
    <td>0.0026573</td>
    <td>0.019394186</td>
  </tr>
  <tr>
    <td>Grk5</td>
    <td>0.860516313</td>
    <td>0.006624137</td>
    <td>0.038468835</td>
    <td>Tbl1x</td>
    <td>0.482959807</td>
    <td>0.00236892</td>
    <td>0.017826308</td>
  </tr>
  <tr>
    <td>Grm3</td>
    <td>0.734008905</td>
    <td>0.000153812</td>
    <td>0.002182809</td>
    <td>Tbl1xr1</td>
    <td>0.822800589</td>
    <td>0.001950136</td>
    <td>0.015462837</td>
  </tr>
  <tr>
    <td>Grpel2</td>
    <td>0.460974888</td>
    <td>0.00438976</td>
    <td>0.02828024</td>
    <td>Tbl2</td>
    <td>0.600512124</td>
    <td>0.009516776</td>
    <td>0.049984891</td>
  </tr>
  <tr>
    <td>Gstcd</td>
    <td>2.435312042</td>
    <td>1.01E-28</td>
    <td>5.76E-26</td>
    <td>Tcaf1</td>
    <td>0.843645766</td>
    <td>0.001694652</td>
    <td>0.013964254</td>
  </tr>
  <tr>
    <td>Gstm1</td>
    <td>0.762528774</td>
    <td>1.55E-05</td>
    <td>0.000338997</td>
    <td>Tcof1</td>
    <td>0.679425051</td>
    <td>0.008921601</td>
    <td>0.047774796</td>
  </tr>
  <tr>
    <td>Gstm6</td>
    <td>0.675038322</td>
    <td>0.008092664</td>
    <td>0.044720316</td>
    <td>Tdrd6</td>
    <td>1.095711326</td>
    <td>0.007191322</td>
    <td>0.040760886</td>
  </tr>
  <tr>
    <td>Gtf2a1</td>
    <td>0.865255401</td>
    <td>4.61E-06</td>
    <td>0.000126157</td>
    <td>Tdrd7</td>
    <td>0.66525201</td>
    <td>0.000135116</td>
    <td>0.001961672</td>
  </tr>
  <tr>
    <td>Gtf2ird2</td>
    <td>0.90418922</td>
    <td>0.002533114</td>
    <td>0.018689871</td>
    <td>Tecpr1</td>
    <td>0.448770505</td>
    <td>0.003560236</td>
    <td>0.024087022</td>
  </tr>
  <tr>
    <td>Gtf3c1</td>
    <td>1.028886878</td>
    <td>0.000403188</td>
    <td>0.004616275</td>
    <td>Tecpr2</td>
    <td>1.014116083</td>
    <td>0.002405362</td>
    <td>0.018028772</td>
  </tr>
  <tr>
    <td>Gtf3c4</td>
    <td>1.064895044</td>
    <td>0.000126565</td>
    <td>0.001858939</td>
    <td>Tedc1</td>
    <td>0.738947376</td>
    <td>0.000882518</td>
    <td>0.008528748</td>
  </tr>
  <tr>
    <td>Gxylt1</td>
    <td>0.904403849</td>
    <td>0.005098253</td>
    <td>0.031576759</td>
    <td>Tef</td>
    <td>0.582145571</td>
    <td>0.000374386</td>
    <td>0.004339069</td>
  </tr>
  <tr>
    <td>Gzf1</td>
    <td>0.613848827</td>
    <td>0.000440995</td>
    <td>0.004959766</td>
    <td>Tent2</td>
    <td>0.56520728</td>
    <td>0.004532224</td>
    <td>0.02898262</td>
  </tr>
  <tr>
    <td>H2-Q1</td>
    <td>7.517110871</td>
    <td>8.97E-08</td>
    <td>4.32E-06</td>
    <td>Tent5c</td>
    <td>1.116649491</td>
    <td>0.008738244</td>
    <td>0.047125088</td>
  </tr>
  <tr>
    <td>H2-Q10</td>
    <td>5.276753046</td>
    <td>0.000767153</td>
    <td>0.007636386</td>
    <td>Terf2ip</td>
    <td>0.648533158</td>
    <td>0.003079944</td>
    <td>0.021707751</td>
  </tr>
  <tr>
    <td>H2-Q4</td>
    <td>2.536448671</td>
    <td>4.41E-06</td>
    <td>0.000121735</td>
    <td>Tescl</td>
    <td>5.829387401</td>
    <td>0.000171786</td>
    <td>0.00237547</td>
  </tr>
  <tr>
    <td>H2-Q5</td>
    <td>4.541820938</td>
    <td>0.001620323</td>
    <td>0.013492932</td>
    <td>Tex2</td>
    <td>0.934237023</td>
    <td>5.60E-07</td>
    <td>2.13E-05</td>
  </tr>
  <tr>
    <td>Hbs1l</td>
    <td>0.518369003</td>
    <td>0.001241649</td>
    <td>0.011102599</td>
    <td>Tfdp2</td>
    <td>0.649689117</td>
    <td>0.000566067</td>
    <td>0.006008062</td>
  </tr>
  <tr>
    <td>Hcfc1</td>
    <td>0.814793168</td>
    <td>0.000334326</td>
    <td>0.003992269</td>
    <td>Tfip11</td>
    <td>0.527557368</td>
    <td>0.00220318</td>
    <td>0.016898132</td>
  </tr>
  <tr>
    <td>Hdac11</td>
    <td>0.708275626</td>
    <td>0.001777888</td>
    <td>0.014454805</td>
    <td>Tgfa</td>
    <td>0.883705173</td>
    <td>2.26E-06</td>
    <td>6.96E-05</td>
  </tr>
  <tr>
    <td>Hddc3</td>
    <td>2.216521684</td>
    <td>5.74E-29</td>
    <td>3.39E-26</td>
    <td>Tgfbr1</td>
    <td>0.970650179</td>
    <td>2.86E-06</td>
    <td>8.46E-05</td>
  </tr>
  <tr>
    <td>HDhd2</td>
    <td>0.892203603</td>
    <td>2.42E-05</td>
    <td>0.00049094</td>
    <td>Tgfbrap1</td>
    <td>0.925813014</td>
    <td>3.30E-06</td>
    <td>9.59E-05</td>
  </tr>
  <tr>
    <td>HDibp</td>
    <td>0.928025292</td>
    <td>7.28E-05</td>
    <td>0.001193507</td>
    <td>Tgoln1</td>
    <td>0.64809368</td>
    <td>0.007628965</td>
    <td>0.042632926</td>
  </tr>
  <tr>
    <td>Heatr1</td>
    <td>0.799434954</td>
    <td>0.003985982</td>
    <td>0.026271621</td>
    <td>Thrap3</td>
    <td>0.951585777</td>
    <td>6.14E-07</td>
    <td>2.28E-05</td>
  </tr>
  <tr>
    <td>Heatr5a</td>
    <td>0.776236069</td>
    <td>0.000693274</td>
    <td>0.007049464</td>
    <td>Thrb</td>
    <td>1.483961096</td>
    <td>0.000311157</td>
    <td>0.003784945</td>
  </tr>
  <tr>
    <td>Heatr5b</td>
    <td>1.126323406</td>
    <td>0.000280602</td>
    <td>0.003491912</td>
    <td>Thsd1</td>
    <td>1.21396672</td>
    <td>7.20E-07</td>
    <td>2.62E-05</td>
  </tr>
  <tr>
    <td>Heca</td>
    <td>0.637462614</td>
    <td>0.004353789</td>
    <td>0.028117418</td>
    <td>Thtpa</td>
    <td>0.791754782</td>
    <td>9.80E-06</td>
    <td>0.000235598</td>
  </tr>
  <tr>
    <td>Hecw2</td>
    <td>0.908654723</td>
    <td>3.75E-05</td>
    <td>0.000700337</td>
    <td>Timm29</td>
    <td>0.696433353</td>
    <td>0.000127144</td>
    <td>0.001865995</td>
  </tr>
  <tr>
    <td>Heg1</td>
    <td>0.795899671</td>
    <td>0.002998645</td>
    <td>0.021269925</td>
    <td>Tjp1</td>
    <td>1.094745906</td>
    <td>1.85E-06</td>
    <td>5.93E-05</td>
  </tr>
  <tr>
    <td>Hgs</td>
    <td>0.617974581</td>
    <td>0.002515295</td>
    <td>0.018575777</td>
    <td>Tjp2</td>
    <td>1.010392469</td>
    <td>6.56E-07</td>
    <td>2.41E-05</td>
  </tr>
  <tr>
    <td>Hhip</td>
    <td>0.88732283</td>
    <td>5.36E-05</td>
    <td>0.000941569</td>
    <td>Tlk1</td>
    <td>0.774045474</td>
    <td>0.002136291</td>
    <td>0.016489307</td>
  </tr>
  <tr>
    <td>Hif1a</td>
    <td>0.866968476</td>
    <td>4.64E-07</td>
    <td>1.82E-05</td>
    <td>Tll2</td>
    <td>0.624327082</td>
    <td>0.000189602</td>
    <td>0.002567362</td>
  </tr>
  <tr>
    <td>Hif1an</td>
    <td>0.990525659</td>
    <td>7.59E-07</td>
    <td>2.75E-05</td>
    <td>Tln1</td>
    <td>1.173044324</td>
    <td>2.85E-07</td>
    <td>1.20E-05</td>
  </tr>
  <tr>
    <td>Hinfp</td>
    <td>0.612447636</td>
    <td>0.003403064</td>
    <td>0.023307292</td>
    <td>Tm9sf3</td>
    <td>0.815131864</td>
    <td>7.73E-05</td>
    <td>0.001253806</td>
  </tr>
  <tr>
    <td>Hipk1</td>
    <td>0.654374351</td>
    <td>0.001869382</td>
    <td>0.014966932</td>
    <td>Tm9sf4</td>
    <td>0.597282955</td>
    <td>0.001945065</td>
    <td>0.015435583</td>
  </tr>
  <tr>
    <td>Hipk3</td>
    <td>1.29498032</td>
    <td>1.05E-09</td>
    <td>8.17E-08</td>
    <td>Tmc7</td>
    <td>0.743021157</td>
    <td>3.32E-06</td>
    <td>9.60E-05</td>
  </tr>
  <tr>
    <td>Hk1</td>
    <td>0.723538027</td>
    <td>0.00459855</td>
    <td>0.029307616</td>
    <td>Tmcc2</td>
    <td>0.546920137</td>
    <td>0.002048468</td>
    <td>0.015992143</td>
  </tr>
  <tr>
    <td>Hmga1b</td>
    <td>3.988283118</td>
    <td>5.28E-07</td>
    <td>2.02E-05</td>
    <td>Tmed8</td>
    <td>1.016529658</td>
    <td>5.87E-07</td>
    <td>2.20E-05</td>
  </tr>
  <tr>
    <td>Hmgxb3</td>
    <td>1.006842019</td>
    <td>0.000282456</td>
    <td>0.003501158</td>
    <td>Tmem106b</td>
    <td>1.173853636</td>
    <td>1.31E-08</td>
    <td>8.10E-07</td>
  </tr>
  <tr>
    <td>Hmgxb4</td>
    <td>0.698227018</td>
    <td>0.000362093</td>
    <td>0.004227698</td>
    <td>Tmem123</td>
    <td>0.558287784</td>
    <td>0.000531864</td>
    <td>0.005741761</td>
  </tr>
  <tr>
    <td>Hnrmph2</td>
    <td>0.607140596</td>
    <td>0.008960503</td>
    <td>0.04795293</td>
    <td>Tmem127</td>
    <td>0.774901134</td>
    <td>0.002354639</td>
    <td>0.017747104</td>
  </tr>
  <tr>
    <td>Hnrmp1l</td>
    <td>0.564283003</td>
    <td>0.00851977</td>
    <td>0.04630512</td>
    <td>Tmem131</td>
    <td>1.003971453</td>
    <td>0.006982778</td>
    <td>0.03987778</td>
  </tr>
  <tr>
    <td>Hnrmpr</td>
    <td>0.482722487</td>
    <td>0.003487666</td>
    <td>0.023755907</td>
    <td>Tmem132b</td>
    <td>0.995776555</td>
    <td>4.32E-06</td>
    <td>0.000120035</td>
  </tr>
  <tr>
    <td>Hnrmpu</td>
    <td>0.609759246</td>
    <td>0.001344551</td>
    <td>0.011765922</td>
    <td>Tmem132c</td>
    <td>2.738708069</td>
    <td>1.07E-05</td>
    <td>0.000251136</td>
  </tr>
  <tr>
    <td>Hps5</td>
    <td>0.681208823</td>
    <td>0.001176614</td>
    <td>0.010672524</td>
    <td>Tmem144</td>
    <td>0.629689361</td>
    <td>0.004036427</td>
    <td>0.026520884</td>
  </tr>
  <tr>
    <td>Hr</td>
    <td>0.91795243</td>
    <td>3.42E-05</td>
    <td>0.000647543</td>
    <td>Tmem150c</td>
    <td>3.27866125</td>
    <td>2.65E-10</td>
    <td>2.35E-08</td>
  </tr>
  <tr>
    <td>HS2st1</td>
    <td>0.614098752</td>
    <td>0.004121148</td>
    <td>0.02696057</td>
    <td>Tmem151a</td>
    <td>0.534548512</td>
    <td>0.000836334</td>
    <td>0.008182827</td>
  </tr>
  <tr>
    <td>HS6st1</td>
    <td>1.006990862</td>
    <td>1.43E-06</td>
    <td>4.74E-05</td>
    <td>Tmem161a</td>
    <td>0.610563803</td>
    <td>0.003110114</td>
    <td>0.021855197</td>
  </tr>
  <tr>
    <td>Hsp90b1</td>
    <td>0.683479903</td>
    <td>0.000667368</td>
    <td>0.006837538</td>
    <td>Tmem167b</td>
    <td>0.64458639</td>
    <td>0.00179736</td>
    <td>0.014569249</td>
  </tr>
  <tr>
    <td>Hspa12a</td>
    <td>0.700012838</td>
    <td>0.003400743</td>
    <td>0.023299838</td>
    <td>Tmem168</td>
    <td>0.630058598</td>
    <td>0.006890731</td>
    <td>0.039531254</td>
  </tr>
  <tr>
    <td>Hspa4</td>
    <td>0.810325561</td>
    <td>4.11E-07</td>
    <td>1.64E-05</td>
    <td>Tmem170b</td>
    <td>1.013033798</td>
    <td>0.001247671</td>
    <td>0.011123488</td>
  </tr>
  <tr>
    <td>Hspa4l</td>
    <td>1.100340428</td>
    <td>6.59E-06</td>
    <td>0.000170092</td>
    <td>Tmem181a</td>
    <td>0.563310141</td>
    <td>0.005742368</td>
    <td>0.034569419</td>
  </tr>
  <tr>
    <td>Hspa8</td>
    <td>0.63026425</td>
    <td>0.003870439</td>
    <td>0.025689221</td>
    <td>Tmem184b</td>
    <td>0.899495383</td>
    <td>2.60E-06</td>
    <td>7.79E-05</td>
  </tr>
  <tr>
    <td>Hspa9</td>
    <td>0.807139571</td>
    <td>4.33E-05</td>
    <td>0.000784609</td>
    <td>Tmem201</td>
    <td>0.632482587</td>
    <td>0.000220214</td>
    <td>0.002880764</td>
  </tr>
  <tr>
    <td>Hspg2</td>
    <td>1.66080045</td>
    <td>7.95E-12</td>
    <td>9.17E-10</td>
    <td>Tmem229a</td>
    <td>0.931721029</td>
    <td>0.000307065</td>
    <td>0.003752068</td>
  </tr>
  <tr>
    <td>Hsph1</td>
    <td>0.705702554</td>
    <td>0.006285278</td>
    <td>0.037001127</td>
    <td>Tmem245</td>
    <td>0.636479667</td>
    <td>0.005486886</td>
    <td>0.0333593</td>
  </tr>
  <tr>
    <td>Htra1</td>
    <td>1.162565569</td>
    <td>0.001368876</td>
    <td>0.01185944</td>
    <td>Tmem263</td>
    <td>0.675422794</td>
    <td>0.000243154</td>
    <td>0.003114052</td>
  </tr>
  <tr>
    <td>Hunk</td>
    <td>0.910827508</td>
    <td>3.77E-07</td>
    <td>1.52E-05</td>
    <td>Tmem30a</td>
    <td>0.784042677</td>
    <td>0.000111526</td>
    <td>0.001681972</td>
  </tr>
  <tr>
    <td>Hus1</td>
    <td>0.854616374</td>
    <td>1.40E-05</td>
    <td>0.000312694</td>
    <td>Tmem56</td>
    <td>0.870891388</td>
    <td>0.000103746</td>
    <td>0.001593103</td>
  </tr>
  <tr>
    <td>Hyou1</td>
    <td>0.67358837</td>
    <td>0.002990313</td>
    <td>0.021234368</td>
    <td>Tmem8b</td>
    <td>0.742380337</td>
    <td>0.002296378</td>
    <td>0.017377275</td>
  </tr>
  <tr>
    <td>lars2</td>
    <td>0.510218881</td>
    <td>0.007023537</td>
    <td>0.040050053</td>
    <td>Tmem94</td>
    <td>0.897441966</td>
    <td>0.003172149</td>
    <td>0.022203686</td>
  </tr>
  <tr>
    <td>lbtk</td>
    <td>0.900721293</td>
    <td>2.30E-05</td>
    <td>0.000472639</td>
    <td>Tmod2</td>
    <td>0.632130572</td>
    <td>0.002770986</td>
    <td>0.020023848</td>
  </tr>
  <tr>
    <td>lcmt</td>
    <td>1.110577287</td>
    <td>1.62E-07</td>
    <td>7.29E-06</td>
    <td>Tmo</td>
    <td>6.009888195</td>
    <td>0.004191347</td>
    <td>0.27339701</td>
  </tr>
  <tr>
    <td>Ids</td>
    <td>0.629048911</td>
    <td>0.002809412</td>
    <td>0.020215574</td>
    <td>Tmtc2</td>
    <td>0.637172173</td>
    <td>0.001607505</td>
    <td>0.013412599</td>
  </tr>
  <tr>
    <td>lft2</td>
    <td>1.144835321</td>
    <td>1.15E-06</td>
    <td>3.96E-05</td>
    <td>Tmtc3</td>
    <td>1.195685743</td>
    <td>6.28E-05</td>
    <td>0.001067668</td>
  </tr>
  <tr>
    <td>Ifnar1</td>
    <td>0.704650652</td>
    <td>0.000281944</td>
    <td>0.003499316</td>
    <td>Tmx3</td>
    <td>0.618466409</td>
    <td>0.003918131</td>
    <td>0.025878558</td>
  </tr>
  <tr>
    <td>lft122</td>
    <td>0.7057515319</td>
    <td>0.003837617</td>
    <td>0.025507198</td>
    <td>Tmx4</td>
    <td>0.937114721</td>
    <td>1.25E-06</td>
    <td>4.23E-05</td>
  </tr>
  <tr>
    <td>lft140</td>
    <td>0.764998581</td>
    <td>0.000285613</td>
    <td>0.003533335</td>
    <td>Tnfrsf19</td>
    <td>1.190409752</td>
    <td>0.000386926</td>
    <td>0.004457076</td>
  </tr>
</table>
<table>
  <tr>
    <td>lft80</td>
    <td>0.877226091</td>
    <td>0.000149918</td>
    <td>0.002135573</td>
    <td>Tnfs9</td>
    <td>0.754135078</td>
    <td>0.001317804</td>
    <td>0.011590277</td>
  </tr>
  <tr>
    <td>Igf2r</td>
    <td>1.406735556</td>
    <td>1.16E-05</td>
    <td>0.000267929</td>
    <td>Tnks</td>
    <td>1.38266153</td>
    <td>2.92E-07</td>
    <td>1.22E-05</td>
  </tr>
  <tr>
    <td>Igsf11</td>
    <td>0.710842619</td>
    <td>0.001037448</td>
    <td>0.0097228</td>
    <td>Tnks1bp1</td>
    <td>1.309790374</td>
    <td>6.17E-08</td>
    <td>3.10E-06</td>
  </tr>
  <tr>
    <td>Ikbkg</td>
    <td>0.761784674</td>
    <td>0.000178831</td>
    <td>0.00245315</td>
    <td>Tnks2</td>
    <td>0.796068303</td>
    <td>0.002939049</td>
    <td>0.020956942</td>
  </tr>
  <tr>
    <td>Il12rb1</td>
    <td>1.184232065</td>
    <td>0.002160366</td>
    <td>0.016654728</td>
    <td>Tnn</td>
    <td>7.176997673</td>
    <td>8.17E-13</td>
    <td>1.07E-10</td>
  </tr>
  <tr>
    <td>Il13ra2</td>
    <td>2.188866577</td>
    <td>0.004618113</td>
    <td>0.029405713</td>
    <td>Tnpo1</td>
    <td>0.974748307</td>
    <td>2.83E-05</td>
    <td>0.000554563</td>
  </tr>
  <tr>
    <td>Il17rb</td>
    <td>0.92680207</td>
    <td>2.43E-06</td>
    <td>7.41E-05</td>
    <td>Tnpo2</td>
    <td>0.561267107</td>
    <td>0.001808391</td>
    <td>0.014633568</td>
  </tr>
  <tr>
    <td>Il1rap</td>
    <td>0.889898582</td>
    <td>3.05E-05</td>
    <td>0.000590902</td>
    <td>Tns1</td>
    <td>1.607693455</td>
    <td>1.72E-10</td>
    <td>1.62E-08</td>
  </tr>
  <tr>
    <td>Il3ra</td>
    <td>3.205091162</td>
    <td>2.89E-05</td>
    <td>0.000565521</td>
    <td>Tns3</td>
    <td>0.907804038</td>
    <td>0.001710902</td>
    <td>0.014049574</td>
  </tr>
  <tr>
    <td>Il6st</td>
    <td>1.006691938</td>
    <td>2.03E-05</td>
    <td>0.000427697</td>
    <td>Tollip</td>
    <td>0.721188049</td>
    <td>0.000140349</td>
    <td>0.002020732</td>
  </tr>
  <tr>
    <td>Ilf3</td>
    <td>0.589966154</td>
    <td>0.000270033</td>
    <td>0.0033849</td>
    <td>Tom1l2</td>
    <td>0.984396895</td>
    <td>2.77E-05</td>
    <td>0.000545228</td>
  </tr>
  <tr>
    <td>Immt</td>
    <td>0.378708781</td>
    <td>0.008551723</td>
    <td>0.046388347</td>
    <td>Tomm70a</td>
    <td>0.588115095</td>
    <td>0.001280248</td>
    <td>0.01135109</td>
  </tr>
  <tr>
    <td>Impact</td>
    <td>0.497257727</td>
    <td>0.000891569</td>
    <td>0.008603027</td>
    <td>Top2b</td>
    <td>1.019140502</td>
    <td>8.76E-05</td>
    <td>0.001401121</td>
  </tr>
  <tr>
    <td>Impg2</td>
    <td>3.442905162</td>
    <td>0.002495413</td>
    <td>0.018457389</td>
    <td>Topbp1</td>
    <td>0.832473176</td>
    <td>0.000553767</td>
    <td>0.005916811</td>
  </tr>
  <tr>
    <td>Inip</td>
    <td>0.481651673</td>
    <td>0.003427029</td>
    <td>0.023412047</td>
    <td>Tor1aip1</td>
    <td>0.708766027</td>
    <td>2.38E-05</td>
    <td>0.00048459</td>
  </tr>
  <tr>
    <td>Ints1</td>
    <td>0.803110646</td>
    <td>0.00031295</td>
    <td>0.003801855</td>
    <td>Tox3</td>
    <td>2.574174943</td>
    <td>5.06E-18</td>
    <td>1.21E-15</td>
  </tr>
  <tr>
    <td>Ip6k1</td>
    <td>0.749965446</td>
    <td>0.006930128</td>
    <td>0.039683879</td>
    <td>Tpd52</td>
    <td>0.366220868</td>
    <td>0.007816696</td>
    <td>0.043496909</td>
  </tr>
  <tr>
    <td>Ipmk</td>
    <td>0.899638037</td>
    <td>6.99E-07</td>
    <td>2.56E-05</td>
    <td>Tppp</td>
    <td>1.285705441</td>
    <td>7.68E-06</td>
    <td>0.000190584</td>
  </tr>
  <tr>
    <td>lpo13</td>
    <td>0.461863301</td>
    <td>0.001933697</td>
    <td>0.015358268</td>
    <td>Traf6</td>
    <td>0.993190212</td>
    <td>4.33E-06</td>
    <td>0.000120077</td>
  </tr>
  <tr>
    <td>lpo7</td>
    <td>0.667109501</td>
    <td>0.003237692</td>
    <td>0.022509041</td>
    <td>Trappc12</td>
    <td>0.586880017</td>
    <td>0.005526346</td>
    <td>0.033503695</td>
  </tr>
  <tr>
    <td>lpo9</td>
    <td>0.961121197</td>
    <td>8.15E-08</td>
    <td>3.96E-06</td>
    <td>Trappc8</td>
    <td>0.943731812</td>
    <td>7.80E-05</td>
    <td>0.001262747</td>
  </tr>
  <tr>
    <td>Iqcf3</td>
    <td>2.840437465</td>
    <td>1.18E-06</td>
    <td>4.03E-05</td>
    <td>Trim17</td>
    <td>0.942311457</td>
    <td>0.003759205</td>
    <td>0.025136276</td>
  </tr>
  <tr>
    <td>Iqub</td>
    <td>2.928871862</td>
    <td>0.00339437</td>
    <td>0.0232646</td>
    <td>Trim25</td>
    <td>0.747909817</td>
    <td>0.001108613</td>
    <td>0.010212528</td>
  </tr>
  <tr>
    <td>Ireb2</td>
    <td>0.775362663</td>
    <td>0.001243043</td>
    <td>0.011105096</td>
    <td>Trim28</td>
    <td>0.466717353</td>
    <td>0.000949958</td>
    <td>0.009087581</td>
  </tr>
  <tr>
    <td>Irgg</td>
    <td>0.7822097</td>
    <td>0.008185791</td>
    <td>0.04506599</td>
    <td>Trim36</td>
    <td>0.561631118</td>
    <td>0.001063664</td>
    <td>0.009924204</td>
  </tr>
  <tr>
    <td>lrsl</td>
    <td>1.00864874</td>
    <td>0.004230425</td>
    <td>0.027508679</td>
    <td>Trim44</td>
    <td>1.33604462</td>
    <td>3.39E-06</td>
    <td>9.74E-05</td>
  </tr>
  <tr>
    <td>Isoc1</td>
    <td>0.571783206</td>
    <td>0.004578163</td>
    <td>0.029197371</td>
    <td>Trip12</td>
    <td>0.683795444</td>
    <td>0.000362016</td>
    <td>0.004227698</td>
  </tr>
  <tr>
    <td>Itch</td>
    <td>0.980800717</td>
    <td>1.82E-06</td>
    <td>5.85E-05</td>
    <td>Tro</td>
    <td>1.151911664</td>
    <td>0.001360038</td>
    <td>0.011822659</td>
  </tr>
  <tr>
    <td>Itgav</td>
    <td>1.183741721</td>
    <td>1.07E-05</td>
    <td>0.000251136</td>
    <td>Trp53bp1</td>
    <td>0.84448203</td>
    <td>0.008965014</td>
    <td>0.04795293</td>
  </tr>
  <tr>
    <td>Itgb3</td>
    <td>0.800102615</td>
    <td>5.60E-05</td>
    <td>0.000973172</td>
    <td>Trp53inp1</td>
    <td>0.70639775</td>
    <td>0.000132439</td>
    <td>0.001927243</td>
  </tr>
  <tr>
    <td>Itgb4</td>
    <td>0.570495394</td>
    <td>0.000761701</td>
    <td>0.007606143</td>
    <td>Trpc1</td>
    <td>0.640834737</td>
    <td>0.003214848</td>
    <td>0.022396915</td>
  </tr>
  <tr>
    <td>Itgb8</td>
    <td>1.099831377</td>
    <td>2.03E-06</td>
    <td>6.41E-05</td>
    <td>Tsc2</td>
    <td>0.677649099</td>
    <td>0.0007877</td>
    <td>0.007791675</td>
  </tr>
  <tr>
    <td>Itih5</td>
    <td>1.901818138</td>
    <td>0.002217349</td>
    <td>0.016948866</td>
    <td>Tspan2</td>
    <td>0.577775437</td>
    <td>0.008209801</td>
    <td>0.045139577</td>
  </tr>
  <tr>
    <td>Itpk1</td>
    <td>0.630242437</td>
    <td>0.005982846</td>
    <td>0.035701792</td>
    <td>Tspyl4</td>
    <td>0.807801308</td>
    <td>7.10E-06</td>
    <td>0.000179995</td>
  </tr>
  <tr>
    <td>lvns1abp</td>
    <td>0.521989078</td>
    <td>0.004571342</td>
    <td>0.029163711</td>
    <td>Tsr1</td>
    <td>0.850062957</td>
    <td>0.001818877</td>
    <td>0.014686986</td>
  </tr>
  <tr>
    <td>Jarid2</td>
    <td>0.78429608</td>
    <td>0.000821868</td>
    <td>0.008070533</td>
    <td>Ttc17</td>
    <td>1.039946667</td>
    <td>0.001345086</td>
    <td>0.011765922</td>
  </tr>
  <tr>
    <td>Jmjd4</td>
    <td>0.803282549</td>
    <td>0.008803663</td>
    <td>0.0473175</td>
    <td>Ttc37</td>
    <td>0.961283372</td>
    <td>1.06E-05</td>
    <td>0.000249875</td>
  </tr>
  <tr>
    <td>Josd1</td>
    <td>0.562529013</td>
    <td>0.001454326</td>
    <td>0.012439423</td>
    <td>Ttc7</td>
    <td>0.618288221</td>
    <td>0.003044452</td>
    <td>0.021497674</td>
  </tr>
  <tr>
    <td>Jph1</td>
    <td>0.674905879</td>
    <td>0.000521457</td>
    <td>0.005661752</td>
    <td>Ttc9c</td>
    <td>0.529711703</td>
    <td>0.008185394</td>
    <td>0.04506599</td>
  </tr>
  <tr>
    <td>Jup</td>
    <td>0.635640909</td>
    <td>0.003561943</td>
    <td>0.024089952</td>
    <td>Ttll7</td>
    <td>0.705513305</td>
    <td>0.004595544</td>
    <td>0.029298334</td>
  </tr>
  <tr>
    <td>Kansl1</td>
    <td>0.71570517</td>
    <td>0.003284091</td>
    <td>0.02271545</td>
    <td>Tubgcp5</td>
    <td>0.58622094</td>
    <td>0.004730972</td>
    <td>0.029979743</td>
  </tr>
  <tr>
    <td>Kansl1l</td>
    <td>0.469072611</td>
    <td>0.004288676</td>
    <td>0.027810922</td>
    <td>Tubgcp6</td>
    <td>0.774740838</td>
    <td>0.008644596</td>
    <td>0.0467273</td>
  </tr>
  <tr>
    <td>Kantr</td>
    <td>1.196968772</td>
    <td>2.73E-05</td>
    <td>0.000539469</td>
    <td>Tug1</td>
    <td>0.626517402</td>
    <td>0.000309076</td>
    <td>0.003766902</td>
  </tr>
  <tr>
    <td>Kbtbd8</td>
    <td>0.860947273</td>
    <td>0.001865966</td>
    <td>0.014955827</td>
    <td>Tulp4</td>
    <td>0.525439258</td>
    <td>0.001634193</td>
    <td>0.013560642</td>
  </tr>
  <tr>
    <td>Kcna6</td>
    <td>1.005392478</td>
    <td>2.30E-05</td>
    <td>0.000472905</td>
    <td>Tut7</td>
    <td>0.578226453</td>
    <td>0.002989229</td>
    <td>0.021234368</td>
  </tr>
  <tr>
    <td>Kcnh7</td>
    <td>1.074243281</td>
    <td>1.63E-06</td>
    <td>5.29E-05</td>
    <td>Twsg1</td>
    <td>0.662237575</td>
    <td>0.00230079</td>
    <td>0.017396733</td>
  </tr>
  <tr>
    <td>Kcnj10</td>
    <td>3.06344049</td>
    <td>8.01E-48</td>
    <td>1.08E-44</td>
    <td>Txndc16</td>
    <td>0.610690969</td>
    <td>0.00052791</td>
    <td>0.00571867</td>
  </tr>
  <tr>
    <td>Kcnj2</td>
    <td>0.80808241</td>
    <td>0.008350428</td>
    <td>0.045620851</td>
    <td>Txnrd1</td>
    <td>0.792609017</td>
    <td>0.00047121</td>
    <td>0.005224208</td>
  </tr>
  <tr>
    <td>Kcnma1</td>
    <td>2.590728299</td>
    <td>0.000612355</td>
    <td>0.006381116</td>
    <td>Tyro3</td>
    <td>0.599391348</td>
    <td>0.000298037</td>
    <td>0.003667839</td>
  </tr>
  <tr>
    <td>Kctd20</td>
    <td>0.529402873</td>
    <td>0.001708789</td>
    <td>0.014049574</td>
    <td>Ubap2</td>
    <td>0.661983374</td>
    <td>0.00503856</td>
    <td>0.031371511</td>
  </tr>
  <tr>
    <td>Kdm2a</td>
    <td>0.429687163</td>
    <td>0.003316785</td>
    <td>0.022882182</td>
    <td>Ube2h</td>
    <td>0.578176607</td>
    <td>0.001448565</td>
    <td>0.012395759</td>
  </tr>
  <tr>
    <td>Kdm3a</td>
    <td>0.693312529</td>
    <td>0.006328984</td>
    <td>0.037142746</td>
    <td>Ube2o</td>
    <td>0.603077634</td>
    <td>0.000490784</td>
    <td>0.005409493</td>
  </tr>
  <tr>
    <td>Kdm4b</td>
    <td>0.714646385</td>
    <td>0.000989934</td>
    <td>0.009359735</td>
    <td>Ube3b</td>
    <td>0.855336232</td>
    <td>1.19E-05</td>
    <td>0.000272491</td>
  </tr>
  <tr>
    <td>Kdm4c</td>
    <td>0.703538267</td>
    <td>0.000440851</td>
    <td>0.004959766</td>
    <td>Ube4a</td>
    <td>0.881714153</td>
    <td>4.78E-06</td>
    <td>0.000130257</td>
  </tr>
  <tr>
    <td>Kdm7a</td>
    <td>0.769598845</td>
    <td>0.000252183</td>
    <td>0.003212279</td>
    <td>Ube4b</td>
    <td>0.445554466</td>
    <td>0.009520742</td>
    <td>0.049991832</td>
  </tr>
  <tr>
    <td>Keap1</td>
    <td>0.446664882</td>
    <td>0.007820885</td>
    <td>0.043507414</td>
    <td>Ubiad1</td>
    <td>0.696190609</td>
    <td>0.005831718</td>
    <td>0.035018095</td>
  </tr>
  <tr>
    <td>Khyn</td>
    <td>0.786798461</td>
    <td>1.19E-05</td>
    <td>0.000271706</td>
    <td>Ubqln1</td>
    <td>1.021365546</td>
    <td>5.86E-06</td>
    <td>0.000155043</td>
  </tr>
  <tr>
    <td>Khsrp</td>
    <td>0.871599274</td>
    <td>8.96E-05</td>
    <td>0.001423031</td>
    <td>Ubr2</td>
    <td>0.509910661</td>
    <td>0.004997041</td>
    <td>0.031183647</td>
  </tr>
  <tr>
    <td>Kidins220</td>
    <td>0.956640628</td>
    <td>0.000564607</td>
    <td>0.00599818</td>
    <td>Ubr3</td>
    <td>0.744729261</td>
    <td>0.000493803</td>
    <td>0.005430114</td>
  </tr>
  <tr>
    <td>Kif13a</td>
    <td>0.964831449</td>
    <td>9.12E-05</td>
    <td>0.001436071</td>
    <td>Uck2</td>
    <td>0.614384969</td>
    <td>0.00073527</td>
    <td>0.007408749</td>
  </tr>
  <tr>
    <td>Kif13b</td>
    <td>1.187257896</td>
    <td>6.97E-06</td>
    <td>0.000177033</td>
    <td>Ufl1</td>
    <td>0.491246457</td>
    <td>0.002261574</td>
    <td>0.017182286</td>
  </tr>
  <tr>
    <td>Kif16b</td>
    <td>0.837315243</td>
    <td>0.000548881</td>
    <td>0.005875143</td>
    <td>Ugcg</td>
    <td>0.820009764</td>
    <td>0.000749379</td>
    <td>0.007510876</td>
  </tr>
  <tr>
    <td>Kif1a</td>
    <td>0.867904856</td>
    <td>8.22E-06</td>
    <td>0.000201451</td>
    <td>Ugt8a</td>
    <td>0.779235511</td>
    <td>0.000414061</td>
    <td>0.004720742</td>
  </tr>
  <tr>
    <td>Kif1b</td>
    <td>1.199085285</td>
    <td>1.35E-06</td>
    <td>4.50E-05</td>
    <td>Uhmk1</td>
    <td>1.453758538</td>
    <td>2.75E-08</td>
    <td>1.55E-06</td>
  </tr>
  <tr>
    <td>Kif3c</td>
    <td>0.889282726</td>
    <td>2.30E-05</td>
    <td>0.00047327</td>
    <td>Uhrf1bp1</td>
    <td>1.386328404</td>
    <td>2.76E-08</td>
    <td>1.55E-06</td>
  </tr>
  <tr>
    <td>Kl</td>
    <td>1.496371842</td>
    <td>0.000634174</td>
    <td>0.006579472</td>
    <td>Uhrf1bp1l</td>
    <td>0.501780205</td>
    <td>0.003087</td>
    <td>0.021741268</td>
  </tr>
  <tr>
    <td>Klc3</td>
    <td>3.103024139</td>
    <td>0.000636028</td>
    <td>0.00659147</td>
    <td>Ulk1</td>
    <td>0.607329334</td>
    <td>0.004733351</td>
    <td>0.029984766</td>
  </tr>
  <tr>
    <td>Klhdc10</td>
    <td>0.833381436</td>
    <td>4.07E-05</td>
    <td>0.000749203</td>
    <td>Ulk2</td>
    <td>0.983371311</td>
    <td>0.000189507</td>
    <td>0.002567362</td>
  </tr>
  <tr>
    <td>Klhl11</td>
    <td>0.959973952</td>
    <td>0.001164249</td>
    <td>0.01059086</td>
    <td>Unc119b</td>
    <td>0.515560842</td>
    <td>0.009456699</td>
    <td>0.049780002</td>
  </tr>
  <tr>
    <td>Klhl2</td>
    <td>0.703742448</td>
    <td>0.001297196</td>
    <td>0.011451557</td>
    <td>Urb2</td>
    <td>0.962299444</td>
    <td>0.000823767</td>
    <td>0.008080779</td>
  </tr>
</table>
<table>
  <tr>
    <td>Klhl22</td>
    <td>0.57903702</td>
    <td>0.001872851</td>
    <td>0.014982015</td>
    <td>Uri1</td>
    <td>0.645663686</td>
    <td>0.000309849</td>
    <td>0.003773885</td>
  </tr>
  <tr>
    <td>Klhl24</td>
    <td>0.941100021</td>
    <td>2.93E-05</td>
    <td>0.000570976</td>
    <td>Uso1</td>
    <td>0.608058035</td>
    <td>0.007187901</td>
    <td>0.040756781</td>
  </tr>
  <tr>
    <td>Klhl33</td>
    <td>4.118835345</td>
    <td>1.99E-08</td>
    <td>1.17E-06</td>
    <td>Usp10</td>
    <td>0.801796893</td>
    <td>7.16E-06</td>
    <td>0.000180687</td>
  </tr>
  <tr>
    <td>Klhl4</td>
    <td>0.649664511</td>
    <td>0.001041368</td>
    <td>0.009754701</td>
    <td>Usp11</td>
    <td>0.544867529</td>
    <td>0.005910654</td>
    <td>0.035402122</td>
  </tr>
  <tr>
    <td>Klhl42</td>
    <td>0.869105899</td>
    <td>0.00709542</td>
    <td>0.040400828</td>
    <td>Usp22</td>
    <td>0.70101686</td>
    <td>1.71E-05</td>
    <td>0.000368643</td>
  </tr>
  <tr>
    <td>Klhl7</td>
    <td>0.474727398</td>
    <td>0.007492437</td>
    <td>0.042026568</td>
    <td>Usp25</td>
    <td>0.519166729</td>
    <td>0.006705247</td>
    <td>0.038784973</td>
  </tr>
  <tr>
    <td>Klrg2</td>
    <td>1.338366524</td>
    <td>1.78E-05</td>
    <td>0.000380861</td>
    <td>Usp30</td>
    <td>0.407321758</td>
    <td>0.00714732</td>
    <td>0.040633318</td>
  </tr>
  <tr>
    <td>Kpna1</td>
    <td>0.807578955</td>
    <td>0.001983584</td>
    <td>0.015626048</td>
    <td>Usp31</td>
    <td>0.900556412</td>
    <td>0.001247478</td>
    <td>0.011123488</td>
  </tr>
  <tr>
    <td>Kpna4</td>
    <td>0.442777058</td>
    <td>0.003886508</td>
    <td>0.025750672</td>
    <td>Usp32</td>
    <td>0.859396458</td>
    <td>0.000571434</td>
    <td>0.006046607</td>
  </tr>
  <tr>
    <td>Kpna6</td>
    <td>0.65469381</td>
    <td>0.00108291</td>
    <td>0.010034435</td>
    <td>Usp33</td>
    <td>1.040573429</td>
    <td>4.73E-05</td>
    <td>0.000848783</td>
  </tr>
  <tr>
    <td>Krr1</td>
    <td>0.601703081</td>
    <td>0.000202659</td>
    <td>0.020707323</td>
    <td>Usp38</td>
    <td>0.646736142</td>
    <td>0.003246678</td>
    <td>0.022530083</td>
  </tr>
  <tr>
    <td>Ktn1</td>
    <td>0.896716291</td>
    <td>3.25E-05</td>
    <td>0.000621051</td>
    <td>Usp42</td>
    <td>0.628331463</td>
    <td>0.000320623</td>
    <td>0.003867727</td>
  </tr>
  <tr>
    <td>L3mbtl2</td>
    <td>0.513870317</td>
    <td>0.008348413</td>
    <td>0.045620851</td>
    <td>Usp45</td>
    <td>0.920460901</td>
    <td>0.009446797</td>
    <td>0.049769453</td>
  </tr>
  <tr>
    <td>Lamc1</td>
    <td>1.018692793</td>
    <td>0.000105417</td>
    <td>0.001610918</td>
    <td>Usp46</td>
    <td>0.615559512</td>
    <td>0.002030961</td>
    <td>0.015897001</td>
  </tr>
  <tr>
    <td>Larp4b</td>
    <td>0.62421853</td>
    <td>0.001983945</td>
    <td>0.015626048</td>
    <td>Usp47</td>
    <td>1.006001315</td>
    <td>5.27E-06</td>
    <td>0.000141793</td>
  </tr>
  <tr>
    <td>Lars</td>
    <td>0.552723062</td>
    <td>0.000302089</td>
    <td>0.003705636</td>
    <td>Usp54</td>
    <td>1.259022932</td>
    <td>0.000659693</td>
    <td>0.006777265</td>
  </tr>
  <tr>
    <td>Lats1</td>
    <td>0.975327603</td>
    <td>3.53E-06</td>
    <td>0.000100698</td>
    <td>Usp6nl</td>
    <td>0.925346391</td>
    <td>2.88E-06</td>
    <td>8.50E-05</td>
  </tr>
  <tr>
    <td>Lats2</td>
    <td>1.057465727</td>
    <td>5.00E-05</td>
    <td>0.000891741</td>
    <td>Usp8</td>
    <td>0.877423726</td>
    <td>0.00172205</td>
    <td>0.01411618</td>
  </tr>
  <tr>
    <td>Lcorl</td>
    <td>0.617704749</td>
    <td>0.001867496</td>
    <td>0.014958171</td>
    <td>Usp9x</td>
    <td>1.316166515</td>
    <td>6.04E-08</td>
    <td>3.06E-06</td>
  </tr>
  <tr>
    <td>Ldlr</td>
    <td>0.995593503</td>
    <td>8.67E-05</td>
    <td>0.001389936</td>
    <td>Utp15</td>
    <td>0.558970347</td>
    <td>0.001626293</td>
    <td>0.0135167</td>
  </tr>
  <tr>
    <td>Ldlrad3</td>
    <td>0.686402012</td>
    <td>0.000825989</td>
    <td>0.008094179</td>
    <td>Vcpipl</td>
    <td>0.624356009</td>
    <td>0.003916951</td>
    <td>0.025878558</td>
  </tr>
  <tr>
    <td>Lemd3</td>
    <td>0.865362227</td>
    <td>1.67E-05</td>
    <td>0.000361932</td>
    <td>Vegfb</td>
    <td>0.444869321</td>
    <td>0.007095739</td>
    <td>0.040400828</td>
  </tr>
  <tr>
    <td>Lepr</td>
    <td>3.250941388</td>
    <td>0.009171298</td>
    <td>0.048739119</td>
    <td>Vezf1</td>
    <td>0.923330753</td>
    <td>1.03E-06</td>
    <td>3.60E-05</td>
  </tr>
  <tr>
    <td>Leprotl1</td>
    <td>1.300130278</td>
    <td>1.13E-18</td>
    <td>3.01E-16</td>
    <td>Vkorcl1</td>
    <td>0.785810849</td>
    <td>7.67E-05</td>
    <td>0.001246948</td>
  </tr>
  <tr>
    <td>Lgals8</td>
    <td>0.441064003</td>
    <td>0.004371975</td>
    <td>0.028205954</td>
    <td>Vps11</td>
    <td>0.592800688</td>
    <td>0.000300014</td>
    <td>0.003687362</td>
  </tr>
  <tr>
    <td>Lgalsl</td>
    <td>0.758039037</td>
    <td>0.002733351</td>
    <td>0.019826756</td>
    <td>Vps33a</td>
    <td>0.806642356</td>
    <td>2.27E-06</td>
    <td>6.99E-05</td>
  </tr>
  <tr>
    <td>Lgr4</td>
    <td>0.898636789</td>
    <td>0.003537157</td>
    <td>0.023973786</td>
    <td>Vps37a</td>
    <td>0.651839325</td>
    <td>0.001597198</td>
    <td>0.013363702</td>
  </tr>
  <tr>
    <td>Lhfpl4</td>
    <td>0.87800476</td>
    <td>0.000443615</td>
    <td>0.004979609</td>
    <td>Vps39</td>
    <td>0.707095821</td>
    <td>0.002799396</td>
    <td>0.020174224</td>
  </tr>
  <tr>
    <td>Lig3</td>
    <td>0.776170549</td>
    <td>0.000330733</td>
    <td>0.003954364</td>
    <td>Vps4b</td>
    <td>0.509050889</td>
    <td>0.003040414</td>
    <td>0.021490559</td>
  </tr>
  <tr>
    <td>Lin52</td>
    <td>0.593890497</td>
    <td>0.00181807</td>
    <td>0.014686739</td>
    <td>Vps8</td>
    <td>0.838855136</td>
    <td>0.004617192</td>
    <td>0.029405713</td>
  </tr>
  <tr>
    <td>Lin54</td>
    <td>0.692169883</td>
    <td>3.12E-05</td>
    <td>0.000599806</td>
    <td>Vwa1</td>
    <td>1.066275797</td>
    <td>0.000426451</td>
    <td>0.004844477</td>
  </tr>
  <tr>
    <td>Lin7c</td>
    <td>0.829852157</td>
    <td>3.34E-06</td>
    <td>9.64E-05</td>
    <td>Wac</td>
    <td>0.765881424</td>
    <td>5.14E-05</td>
    <td>0.000908932</td>
  </tr>
  <tr>
    <td>Lingo3</td>
    <td>1.266520204</td>
    <td>0.001243103</td>
    <td>0.011105096</td>
    <td>Wars</td>
    <td>0.601683811</td>
    <td>0.002923426</td>
    <td>0.02087704</td>
  </tr>
  <tr>
    <td>Ligl1</td>
    <td>0.473775624</td>
    <td>0.008622855</td>
    <td>0.046650781</td>
    <td>Wasf1</td>
    <td>0.478554971</td>
    <td>0.002126011</td>
    <td>0.016416661</td>
  </tr>
  <tr>
    <td>Lmbrd1</td>
    <td>0.71338414</td>
    <td>0.000351499</td>
    <td>0.004147773</td>
    <td>Wasf3</td>
    <td>0.875686474</td>
    <td>0.001892812</td>
    <td>0.015084246</td>
  </tr>
  <tr>
    <td>Lmtk2</td>
    <td>1.166359146</td>
    <td>3.07E-06</td>
    <td>9.01E-05</td>
    <td>Washc2</td>
    <td>0.607890686</td>
    <td>0.002468202</td>
    <td>0.18354216</td>
  </tr>
  <tr>
    <td>Lonrf1</td>
    <td>0.654580303</td>
    <td>0.009053167</td>
    <td>0.048274193</td>
    <td>Washc5</td>
    <td>0.67044008</td>
    <td>0.002457703</td>
    <td>0.018299539</td>
  </tr>
  <tr>
    <td>Lpgat1</td>
    <td>0.548722477</td>
    <td>0.0067259</td>
    <td>0.038833137</td>
    <td>Wbp1l</td>
    <td>0.784011782</td>
    <td>0.001240228</td>
    <td>0.011095141</td>
  </tr>
  <tr>
    <td>Lpin1</td>
    <td>0.667819625</td>
    <td>0.00034479</td>
    <td>0.004083688</td>
    <td>Wdfy1</td>
    <td>2.504503797</td>
    <td>2.40E-35</td>
    <td>2.16E-32</td>
  </tr>
  <tr>
    <td>Lpin2</td>
    <td>0.890027047</td>
    <td>0.000253241</td>
    <td>0.003220807</td>
    <td>Wdfy2</td>
    <td>1.13434275</td>
    <td>0.000646414</td>
    <td>0.006677136</td>
  </tr>
  <tr>
    <td>Lratd2</td>
    <td>1.979103448</td>
    <td>3.34E-10</td>
    <td>2.91E-08</td>
    <td>Wdr11</td>
    <td>0.790548511</td>
    <td>0.001401082</td>
    <td>0.012065897</td>
  </tr>
  <tr>
    <td>Lrch1</td>
    <td>0.986595853</td>
    <td>1.02E-05</td>
    <td>0.00024338</td>
    <td>Wdr19</td>
    <td>0.872828417</td>
    <td>0.008410657</td>
    <td>0.045876799</td>
  </tr>
  <tr>
    <td>Lrp6</td>
    <td>1.024756278</td>
    <td>9.44E-05</td>
    <td>0.001473248</td>
    <td>Wdr25</td>
    <td>0.623765327</td>
    <td>0.005112113</td>
    <td>0.031652235</td>
  </tr>
  <tr>
    <td>Lrpprc</td>
    <td>0.589721819</td>
    <td>0.003881135</td>
    <td>0.025733109</td>
    <td>Wdr37</td>
    <td>0.608513334</td>
    <td>0.000366727</td>
    <td>0.004265999</td>
  </tr>
  <tr>
    <td>Lrrc1</td>
    <td>0.642070631</td>
    <td>0.00220891</td>
    <td>0.01690487</td>
    <td>Wdr43</td>
    <td>0.443441707</td>
    <td>0.00513865</td>
    <td>0.031788944</td>
  </tr>
  <tr>
    <td>Lrrc47</td>
    <td>0.531149862</td>
    <td>0.00185902</td>
    <td>0.014917039</td>
    <td>Wdr46</td>
    <td>0.508761494</td>
    <td>0.008283929</td>
    <td>0.045401888</td>
  </tr>
  <tr>
    <td>Lrrc58</td>
    <td>0.701211473</td>
    <td>0.002887479</td>
    <td>0.02066718</td>
    <td>Wdr47</td>
    <td>0.604493843</td>
    <td>0.006798713</td>
    <td>0.039141318</td>
  </tr>
  <tr>
    <td>Lrrc59</td>
    <td>0.497510788</td>
    <td>0.003987536</td>
    <td>0.026272707</td>
    <td>Wdr48</td>
    <td>0.804004067</td>
    <td>9.97E-05</td>
    <td>0.001536168</td>
  </tr>
  <tr>
    <td>Lrrc66</td>
    <td>5.533913209</td>
    <td>4.64E-08</td>
    <td>2.46E-06</td>
    <td>Wdr7</td>
    <td>1.072312556</td>
    <td>7.41E-06</td>
    <td>0.000184843</td>
  </tr>
  <tr>
    <td>Lrrc8d</td>
    <td>0.878395021</td>
    <td>0.000768644</td>
    <td>0.007647201</td>
    <td>Wdr81</td>
    <td>0.76856601</td>
    <td>4.92E-05</td>
    <td>0.000877798</td>
  </tr>
  <tr>
    <td>Lrrn1</td>
    <td>0.841240621</td>
    <td>4.32E-05</td>
    <td>0.000783627</td>
    <td>Wipf1</td>
    <td>0.842791084</td>
    <td>0.003041171</td>
    <td>0.021490559</td>
  </tr>
  <tr>
    <td>Lrrn3</td>
    <td>1.193849338</td>
    <td>0.0004655</td>
    <td>0.005174879</td>
    <td>Wipi2</td>
    <td>0.538282061</td>
    <td>0.000384636</td>
    <td>0.004436107</td>
  </tr>
  <tr>
    <td>Lrtm2</td>
    <td>0.829794334</td>
    <td>0.001386104</td>
    <td>0.011964169</td>
    <td>Wiz</td>
    <td>0.525621891</td>
    <td>0.003299234</td>
    <td>0.022788388</td>
  </tr>
  <tr>
    <td>Lsm14a</td>
    <td>0.686872678</td>
    <td>2.47E-05</td>
    <td>0.000499516</td>
    <td>Wnk3</td>
    <td>1.31475849</td>
    <td>0.001129311</td>
    <td>0.010347733</td>
  </tr>
  <tr>
    <td>Lsm14b</td>
    <td>0.576118523</td>
    <td>0.001197357</td>
    <td>0.010782652</td>
    <td>Wwp2</td>
    <td>0.525015358</td>
    <td>0.007220856</td>
    <td>0.040879257</td>
  </tr>
  <tr>
    <td>Ltbp2</td>
    <td>3.990384793</td>
    <td>0.0048844</td>
    <td>0.030642912</td>
    <td>Xkr8</td>
    <td>1.077750664</td>
    <td>2.10E-07</td>
    <td>9.11E-06</td>
  </tr>
  <tr>
    <td>Ltn1</td>
    <td>0.522134716</td>
    <td>0.005300203</td>
    <td>0.032518575</td>
    <td>Xpo1</td>
    <td>0.860201119</td>
    <td>0.000381478</td>
    <td>0.004410447</td>
  </tr>
  <tr>
    <td>Lurap1</td>
    <td>0.778644324</td>
    <td>0.004384953</td>
    <td>0.028270383</td>
    <td>Xpo7</td>
    <td>1.069442598</td>
    <td>3.39E-06</td>
    <td>9.74E-05</td>
  </tr>
  <tr>
    <td>Luzp1</td>
    <td>0.831311802</td>
    <td>0.006541869</td>
    <td>0.038119897</td>
    <td>Xpot</td>
    <td>0.954004526</td>
    <td>1.45E-05</td>
    <td>0.000321373</td>
  </tr>
  <tr>
    <td>Luzp2</td>
    <td>1.792506622</td>
    <td>3.98E-12</td>
    <td>4.85E-10</td>
    <td>Yes1</td>
    <td>0.834424581</td>
    <td>0.000277293</td>
    <td>0.003461903</td>
  </tr>
  <tr>
    <td>Lysmd3</td>
    <td>0.674057812</td>
    <td>0.001830098</td>
    <td>0.014752384</td>
    <td>Yipf6</td>
    <td>1.086756882</td>
    <td>7.59E-06</td>
    <td>0.000188476</td>
  </tr>
  <tr>
    <td>Maco1</td>
    <td>0.606149565</td>
    <td>0.003177613</td>
    <td>0.022230357</td>
    <td>Ypel2</td>
    <td>0.435377506</td>
    <td>0.001231771</td>
    <td>0.011029923</td>
  </tr>
  <tr>
    <td>Magt1</td>
    <td>0.771589739</td>
    <td>0.00077332</td>
    <td>0.007689674</td>
    <td>Ythdf3</td>
    <td>0.961389388</td>
    <td>1.47E-05</td>
    <td>0.000325351</td>
  </tr>
  <tr>
    <td>Man2a2</td>
    <td>1.322806912</td>
    <td>2.78E-07</td>
    <td>1.18E-05</td>
    <td>Ywhag</td>
    <td>0.608394044</td>
    <td>0.002864927</td>
    <td>0.020529079</td>
  </tr>
  <tr>
    <td>Man2b1</td>
    <td>0.936193475</td>
    <td>5.53E-09</td>
    <td>3.78E-07</td>
    <td>Zbtb1</td>
    <td>0.532696926</td>
    <td>0.00504477</td>
    <td>0.031399832</td>
  </tr>
  <tr>
    <td>Manba</td>
    <td>0.671115863</td>
    <td>0.001075957</td>
    <td>0.009987248</td>
    <td>Zbtb11</td>
    <td>0.526965635</td>
    <td>0.00794135</td>
    <td>0.044022092</td>
  </tr>
  <tr>
    <td>Manea</td>
    <td>0.740496913</td>
    <td>0.001478569</td>
    <td>0.012578589</td>
    <td>Zbtb14</td>
    <td>0.590927799</td>
    <td>0.002046916</td>
    <td>0.015988784</td>
  </tr>
  <tr>
    <td>Map2k4</td>
    <td>0.481197303</td>
    <td>0.000657662</td>
    <td>0.006763758</td>
    <td>Zbtb18</td>
    <td>0.58008297</td>
    <td>0.003679</td>
    <td>0.024748802</td>
  </tr>
  <tr>
    <td>Map3k11</td>
    <td>0.665597804</td>
    <td>1.89E-05</td>
    <td>0.000403278</td>
    <td>Zbtb34</td>
    <td>1.038052307</td>
    <td>0.00023418</td>
    <td>0.003025766</td>
  </tr>
  <tr>
    <td>Map3k13</td>
    <td>1.133031947</td>
    <td>2.39E-06</td>
    <td>7.31E-05</td>
    <td>Zbtb38</td>
    <td>0.529405565</td>
    <td>0.000868578</td>
    <td>0.008424184</td>
  </tr>
</table>
<table>
  <tr>
    <td>Map3k4</td>
    <td>0.524022369</td>
    <td>0.001623258</td>
    <td>0.013505475</td>
    <td>Zbtb41</td>
    <td>1.349482376</td>
    <td>9.09E-10</td>
    <td>7.13E-08</td>
  </tr>
  <tr>
    <td>Map3k7</td>
    <td>0.859537666</td>
    <td>0.002409502</td>
    <td>0.018052645</td>
    <td>Zbtb44</td>
    <td>1.050390608</td>
    <td>2.51E-05</td>
    <td>0.000505917</td>
  </tr>
  <tr>
    <td>Map4k5</td>
    <td>0.825936615</td>
    <td>5.23E-05</td>
    <td>0.00092192</td>
    <td>Zbtb6</td>
    <td>0.820521618</td>
    <td>0.000674414</td>
    <td>0.006892398</td>
  </tr>
  <tr>
    <td>Map6d1</td>
    <td>0.706168698</td>
    <td>5.76E-05</td>
    <td>0.000994211</td>
    <td>Zcchc24</td>
    <td>1.066563028</td>
    <td>9.95E-06</td>
    <td>0.000238151</td>
  </tr>
  <tr>
    <td>Mapk14</td>
    <td>0.455377626</td>
    <td>0.002948412</td>
    <td>0.02099994</td>
    <td>Zdhhc17</td>
    <td>0.658544581</td>
    <td>0.001217051</td>
    <td>0.010913618</td>
  </tr>
  <tr>
    <td>Mapk8ip3</td>
    <td>0.924271033</td>
    <td>4.19E-05</td>
    <td>0.000766337</td>
    <td>Zdhhc18</td>
    <td>0.953559317</td>
    <td>0.001966335</td>
    <td>0.015561168</td>
  </tr>
  <tr>
    <td>Mapk9</td>
    <td>0.617022397</td>
    <td>0.008059717</td>
    <td>0.044573676</td>
    <td>Zdhhc2</td>
    <td>1.686208323</td>
    <td>6.97E-15</td>
    <td>1.19E-12</td>
  </tr>
  <tr>
    <td>Marchf8</td>
    <td>0.835803903</td>
    <td>4.52E-06</td>
    <td>0.000124212</td>
    <td>Zdhhc21</td>
    <td>0.673657273</td>
    <td>0.000473618</td>
    <td>0.005242273</td>
  </tr>
  <tr>
    <td>Marveld2</td>
    <td>2.091179646</td>
    <td>0.005628453</td>
    <td>0.034024512</td>
    <td>Zdhhc3</td>
    <td>0.835015915</td>
    <td>1.72E-05</td>
    <td>0.000369426</td>
  </tr>
  <tr>
    <td>Mast4</td>
    <td>0.59697851</td>
    <td>0.005091918</td>
    <td>0.031558203</td>
    <td>Zdhhc5</td>
    <td>0.749413036</td>
    <td>8.21E-05</td>
    <td>0.001322259</td>
  </tr>
  <tr>
    <td>Matn2</td>
    <td>0.725274331</td>
    <td>5.96E-05</td>
    <td>0.0010241</td>
    <td>Zdhhc8</td>
    <td>0.427311612</td>
    <td>0.003578131</td>
    <td>0.024190775</td>
  </tr>
  <tr>
    <td>Matr3</td>
    <td>0.613563034</td>
    <td>0.000156477</td>
    <td>0.002210675</td>
    <td>Zeb2</td>
    <td>0.797191646</td>
    <td>0.002392868</td>
    <td>0.017963613</td>
  </tr>
  <tr>
    <td>Max</td>
    <td>0.507811289</td>
    <td>0.000572493</td>
    <td>0.006052483</td>
    <td>Zer1</td>
    <td>0.615520764</td>
    <td>0.000669772</td>
    <td>0.006858455</td>
  </tr>
  <tr>
    <td>Mb21d2</td>
    <td>0.531913069</td>
    <td>0.006653876</td>
    <td>0.038594115</td>
    <td>Zfp105</td>
    <td>0.58799026</td>
    <td>0.00849935</td>
    <td>0.046242688</td>
  </tr>
  <tr>
    <td>Mbd5</td>
    <td>0.601227449</td>
    <td>0.008767314</td>
    <td>0.047229564</td>
    <td>Zfp106</td>
    <td>1.357994383</td>
    <td>3.83E-05</td>
    <td>0.000712099</td>
  </tr>
  <tr>
    <td>Mbni1</td>
    <td>0.686797243</td>
    <td>0.000710171</td>
    <td>0.007191402</td>
    <td>Zfp110</td>
    <td>0.478364045</td>
    <td>0.002235555</td>
    <td>0.017032931</td>
  </tr>
  <tr>
    <td>Mboat4</td>
    <td>5.648176288</td>
    <td>0.006718373</td>
    <td>0.038815083</td>
    <td>Zfp12</td>
    <td>0.608237802</td>
    <td>0.009108772</td>
    <td>0.048474976</td>
  </tr>
  <tr>
    <td>Mbtps1</td>
    <td>0.813472831</td>
    <td>7.43E-05</td>
    <td>0.001213504</td>
    <td>Zfp143</td>
    <td>0.705580888</td>
    <td>5.21E-05</td>
    <td>0.000918938</td>
  </tr>
  <tr>
    <td>Mcm3</td>
    <td>0.587867979</td>
    <td>0.005114782</td>
    <td>0.031658393</td>
    <td>Zfp146</td>
    <td>0.893548898</td>
    <td>1.41E-06</td>
    <td>4.69E-05</td>
  </tr>
  <tr>
    <td>Mcm4</td>
    <td>0.898068044</td>
    <td>0.000595939</td>
    <td>0.006251405</td>
    <td>Zfp148</td>
    <td>0.585552391</td>
    <td>0.001703672</td>
    <td>0.014017681</td>
  </tr>
  <tr>
    <td>Mcm7</td>
    <td>0.620575111</td>
    <td>0.001561713</td>
    <td>0.013161418</td>
    <td>Zfp174</td>
    <td>1.14817077</td>
    <td>0.007455005</td>
    <td>0.041878739</td>
  </tr>
  <tr>
    <td>Mcm9</td>
    <td>0.696788263</td>
    <td>0.002581062</td>
    <td>0.018969603</td>
    <td>Zfp180</td>
    <td>0.798789173</td>
    <td>0.002672434</td>
    <td>0.01948959</td>
  </tr>
  <tr>
    <td>Mdc1</td>
    <td>1.68917181</td>
    <td>3.81E-09</td>
    <td>2.70E-07</td>
    <td>Zfp189</td>
    <td>0.539163785</td>
    <td>0.007838683</td>
    <td>0.04356796</td>
  </tr>
  <tr>
    <td>Me1</td>
    <td>0.625260224</td>
    <td>0.009361239</td>
    <td>0.049373744</td>
    <td>Zfp2</td>
    <td>0.697995909</td>
    <td>1.22E-05</td>
    <td>0.000277637</td>
  </tr>
  <tr>
    <td>Mecp2</td>
    <td>0.478041933</td>
    <td>0.006904586</td>
    <td>0.039586711</td>
    <td>Zfp251</td>
    <td>0.679901355</td>
    <td>3.38E-05</td>
    <td>0.00064124</td>
  </tr>
  <tr>
    <td>Med14</td>
    <td>0.639493479</td>
    <td>0.000763627</td>
    <td>0.007621351</td>
    <td>Zfp26</td>
    <td>0.646035643</td>
    <td>0.003284765</td>
    <td>0.02271545</td>
  </tr>
  <tr>
    <td>Med20</td>
    <td>0.533495226</td>
    <td>0.00157181</td>
    <td>0.01322882</td>
    <td>Zfp260</td>
    <td>0.484115695</td>
    <td>0.003698507</td>
    <td>0.024844661</td>
  </tr>
  <tr>
    <td>Med24</td>
    <td>0.691316717</td>
    <td>0.005921125</td>
    <td>0.035453602</td>
    <td>Zfp275</td>
    <td>1.014304252</td>
    <td>6.28E-05</td>
    <td>0.001067668</td>
  </tr>
  <tr>
    <td>Mef2a</td>
    <td>0.650554261</td>
    <td>0.001286516</td>
    <td>0.011392293</td>
    <td>Zfp282</td>
    <td>0.424735359</td>
    <td>0.007835765</td>
    <td>0.04356796</td>
  </tr>
  <tr>
    <td>Mef2b</td>
    <td>2.106651093</td>
    <td>7.73E-07</td>
    <td>2.80E-05</td>
    <td>Zfp292</td>
    <td>0.881178453</td>
    <td>0.002314597</td>
    <td>0.017480154</td>
  </tr>
  <tr>
    <td>Megf10</td>
    <td>1.245268668</td>
    <td>6.73E-07</td>
    <td>2.47E-05</td>
    <td>Zfp316</td>
    <td>0.769459177</td>
    <td>0.000632016</td>
    <td>0.006560675</td>
  </tr>
  <tr>
    <td>Mex3c</td>
    <td>0.754376077</td>
    <td>0.001514843</td>
    <td>0.012846606</td>
    <td>Zfp317</td>
    <td>0.471625769</td>
    <td>0.003590735</td>
    <td>0.024258639</td>
  </tr>
  <tr>
    <td>Mfap1a</td>
    <td>0.596336015</td>
    <td>0.001986681</td>
    <td>0.015634564</td>
    <td>Zfp319</td>
    <td>0.860337673</td>
    <td>9.83E-06</td>
    <td>0.000235952</td>
  </tr>
  <tr>
    <td>Mfap3l</td>
    <td>1.382859886</td>
    <td>1.64E-06</td>
    <td>5.32E-05</td>
    <td>Zfp334</td>
    <td>1.052422169</td>
    <td>3.80E-07</td>
    <td>1.53E-05</td>
  </tr>
  <tr>
    <td>Mfhas1</td>
    <td>1.530074965</td>
    <td>2.59E-06</td>
    <td>7.76E-05</td>
    <td>Zfp354c</td>
    <td>0.775596402</td>
    <td>0.004987592</td>
    <td>0.031146496</td>
  </tr>
  <tr>
    <td>Mfn1</td>
    <td>0.391255165</td>
    <td>0.007447909</td>
    <td>0.041857353</td>
    <td>Zfp365</td>
    <td>0.789633692</td>
    <td>0.001744118</td>
    <td>0.014259975</td>
  </tr>
  <tr>
    <td>Mfn2</td>
    <td>0.552295316</td>
    <td>0.001182062</td>
    <td>0.010701394</td>
    <td>Zfp37</td>
    <td>0.666738706</td>
    <td>6.55E-05</td>
    <td>0.001095028</td>
  </tr>
  <tr>
    <td>Mfsd1</td>
    <td>0.432939083</td>
    <td>0.006716445</td>
    <td>0.038815083</td>
    <td>Zfp39</td>
    <td>1.373994034</td>
    <td>1.57E-08</td>
    <td>9.53E-07</td>
  </tr>
  <tr>
    <td>Mfsd2a</td>
    <td>0.674589004</td>
    <td>0.003891854</td>
    <td>0.025777059</td>
    <td>Zfp397</td>
    <td>0.627864282</td>
    <td>0.004774967</td>
    <td>0.030177603</td>
  </tr>
  <tr>
    <td>Mfsd4a</td>
    <td>1.315007109</td>
    <td>1.58E-05</td>
    <td>0.000343514</td>
    <td>Zfp398</td>
    <td>0.567703444</td>
    <td>0.009031349</td>
    <td>0.048225875</td>
  </tr>
  <tr>
    <td>Mfsd6</td>
    <td>1.170038641</td>
    <td>0.000500768</td>
    <td>0.005481193</td>
    <td>Zfp41</td>
    <td>0.586087187</td>
    <td>0.008594441</td>
    <td>0.046563689</td>
  </tr>
  <tr>
    <td>Mgat3</td>
    <td>0.833323665</td>
    <td>2.03E-05</td>
    <td>0.000427697</td>
    <td>Zfp422</td>
    <td>0.606420908</td>
    <td>0.00294641</td>
    <td>0.020993588</td>
  </tr>
  <tr>
    <td>Mgat4a</td>
    <td>0.942424178</td>
    <td>0.003253986</td>
    <td>0.022564232</td>
    <td>Zfp438</td>
    <td>0.621579596</td>
    <td>0.002853496</td>
    <td>0.020485999</td>
  </tr>
  <tr>
    <td>Mgrn1</td>
    <td>0.382211585</td>
    <td>0.009515236</td>
    <td>0.049984891</td>
    <td>Zfp449</td>
    <td>0.586761389</td>
    <td>0.005632317</td>
    <td>0.034036982</td>
  </tr>
  <tr>
    <td>Mib1</td>
    <td>0.969004458</td>
    <td>0.001096952</td>
    <td>0.010129793</td>
    <td>Zfp46</td>
    <td>0.503430343</td>
    <td>0.009494879</td>
    <td>0.049923324</td>
  </tr>
  <tr>
    <td>Mid1ip1</td>
    <td>0.743296657</td>
    <td>0.00016268</td>
    <td>0.002271159</td>
    <td>Zfp507</td>
    <td>0.723159891</td>
    <td>0.000273881</td>
    <td>0.003428591</td>
  </tr>
  <tr>
    <td>Mid2</td>
    <td>0.850410062</td>
    <td>0.009322417</td>
    <td>0.049223922</td>
    <td>Zfp51</td>
    <td>0.77574753</td>
    <td>0.003152409</td>
    <td>0.022103109</td>
  </tr>
  <tr>
    <td>Miga1</td>
    <td>0.75933645</td>
    <td>7.14E-06</td>
    <td>0.000180341</td>
    <td>Zfp516</td>
    <td>1.140962813</td>
    <td>0.001877043</td>
    <td>0.015002853</td>
  </tr>
  <tr>
    <td>Mkrn1</td>
    <td>0.481232616</td>
    <td>0.008505755</td>
    <td>0.046242688</td>
    <td>Zfp518a</td>
    <td>0.843957447</td>
    <td>9.81E-05</td>
    <td>0.001520618</td>
  </tr>
  <tr>
    <td>Mlec</td>
    <td>0.962925917</td>
    <td>1.47E-05</td>
    <td>0.00032511</td>
    <td>Zfp526</td>
    <td>1.528419049</td>
    <td>8.85E-10</td>
    <td>6.97E-08</td>
  </tr>
  <tr>
    <td>Mllt1</td>
    <td>0.61402085</td>
    <td>0.006290571</td>
    <td>0.037009232</td>
    <td>Zfp553</td>
    <td>0.611931017</td>
    <td>0.001050209</td>
    <td>0.00981805</td>
  </tr>
  <tr>
    <td>Mmp17</td>
    <td>2.105605854</td>
    <td>0.001248693</td>
    <td>0.011123488</td>
    <td>Zfp568</td>
    <td>1.040403778</td>
    <td>2.02E-06</td>
    <td>6.38E-05</td>
  </tr>
  <tr>
    <td>Mnt</td>
    <td>0.868402509</td>
    <td>0.000567705</td>
    <td>0.006015323</td>
    <td>Zfp592</td>
    <td>0.866753743</td>
    <td>0.000161435</td>
    <td>0.002257111</td>
  </tr>
  <tr>
    <td>Mob1a</td>
    <td>0.757388002</td>
    <td>1.44E-05</td>
    <td>0.00032014</td>
    <td>Zfp605</td>
    <td>0.701719287</td>
    <td>0.002989896</td>
    <td>0.021234368</td>
  </tr>
  <tr>
    <td>Mob1b</td>
    <td>0.985404631</td>
    <td>2.45E-05</td>
    <td>0.000496033</td>
    <td>Zfp619</td>
    <td>1.004012127</td>
    <td>0.001026775</td>
    <td>0.009646685</td>
  </tr>
  <tr>
    <td>Mon1b</td>
    <td>1.124150876</td>
    <td>2.94E-07</td>
    <td>1.22E-05</td>
    <td>Zfp629</td>
    <td>0.976079223</td>
    <td>0.00026983</td>
    <td>0.0033846</td>
  </tr>
  <tr>
    <td>Mon2</td>
    <td>0.785721626</td>
    <td>0.000730909</td>
    <td>0.007370445</td>
    <td>Zfp638</td>
    <td>0.908525041</td>
    <td>0.000292216</td>
    <td>0.003604625</td>
  </tr>
  <tr>
    <td>Morc2a</td>
    <td>0.720908134</td>
    <td>0.006735574</td>
    <td>0.038877116</td>
    <td>Zfp646</td>
    <td>0.963119433</td>
    <td>0.000312323</td>
    <td>0.003796688</td>
  </tr>
  <tr>
    <td>Morc4</td>
    <td>1.110349463</td>
    <td>8.98E-05</td>
    <td>0.001423031</td>
    <td>Zfp651</td>
    <td>0.779555478</td>
    <td>0.000308403</td>
    <td>0.003763553</td>
  </tr>
  <tr>
    <td>Mpp2</td>
    <td>0.698913754</td>
    <td>0.001210086</td>
    <td>0.010866629</td>
    <td>Zfp654</td>
    <td>0.946312429</td>
    <td>4.29E-05</td>
    <td>0.00077869</td>
  </tr>
  <tr>
    <td>Mpp5</td>
    <td>0.58665258</td>
    <td>0.002780451</td>
    <td>0.02007629</td>
    <td>Zfp658</td>
    <td>1.266045967</td>
    <td>4.15E-08</td>
    <td>2.22E-06</td>
  </tr>
  <tr>
    <td>Mras</td>
    <td>0.689407375</td>
    <td>0.003293759</td>
    <td>0.022764875</td>
    <td>Zfp664</td>
    <td>0.695538594</td>
    <td>0.000516702</td>
    <td>0.005626274</td>
  </tr>
  <tr>
    <td>Mrs2</td>
    <td>1.139726298</td>
    <td>0.00010497</td>
    <td>0.001605372</td>
    <td>Zfp667</td>
    <td>0.78024074</td>
    <td>0.003201036</td>
    <td>0.022319876</td>
  </tr>
  <tr>
    <td>Msh6</td>
    <td>0.782921017</td>
    <td>0.000289521</td>
    <td>0.003577001</td>
    <td>Zfp687</td>
    <td>0.517547308</td>
    <td>0.000535058</td>
    <td>0.005769657</td>
  </tr>
  <tr>
    <td>Msl2</td>
    <td>0.881385831</td>
    <td>4.19E-08</td>
    <td>2.23E-06</td>
    <td>Zfp709</td>
    <td>0.819952941</td>
    <td>0.002084098</td>
    <td>0.016195163</td>
  </tr>
  <tr>
    <td>Mtcl1</td>
    <td>1.12340402</td>
    <td>0.001421925</td>
    <td>0.012202314</td>
    <td>Zfp738</td>
    <td>0.590588095</td>
    <td>0.005228419</td>
    <td>0.032203588</td>
  </tr>
  <tr>
    <td>Mthfd1</td>
    <td>0.723569959</td>
    <td>0.000305069</td>
    <td>0.003734923</td>
    <td>Zfp74</td>
    <td>0.990248834</td>
    <td>0.000188055</td>
    <td>0.002555573</td>
  </tr>
  <tr>
    <td>Mtmr1</td>
    <td>0.693354655</td>
    <td>0.000519361</td>
    <td>0.005648723</td>
    <td>Zfp758</td>
    <td>0.747035253</td>
    <td>0.009220556</td>
    <td>0.048890929</td>
  </tr>
  <tr>
    <td>Mtmr10</td>
    <td>1.203395709</td>
    <td>8.70E-09</td>
    <td>5.57E-07</td>
    <td>Zfp84</td>
    <td>1.086191456</td>
    <td>1.49E-05</td>
    <td>0.000329049</td>
  </tr>
  <tr>
    <td>Mtmr3</td>
    <td>0.995533485</td>
    <td>2.99E-08</td>
    <td>1.66E-06</td>
    <td>Zfp874a</td>
    <td>0.602092461</td>
    <td>0.000203148</td>
    <td>0.002711935</td>
  </tr>
</table>
<table><caption>**Supplementary Table 1.** List of 1,726 gene transcripts upregulated in adult OLs compared to adult OPCs (log2Foldchange in aOLs compared to aOPCs reported the second column, cut-off pvalue < 0.01 and qvalue < 0.05) and with at least one hyper-hydroxymethylated CpG at the promoter or gene region. Solute carrier family members genes are highlighted (bold typo, grey background cell).</caption><tr><td>Mtmr4</td><td>0.812348998</td><td>0.001820032</td><td>0.014690033</td><td>Zfp91</td><td>0.625054636</td><td>0.000211932</td><td>0.002793689</td></tr><tr><td>Mtmr6</td><td>0.636966781</td><td>0.009186615</td><td>0.048806797</td><td>Zfp933</td><td>1.352761898</td><td>8.47E-10</td><td>6.73E-08</td></tr><tr><td>Mtmr9</td><td>0.62231432</td><td>0.006203515</td><td>0.036633876</td><td>Zfp943</td><td>0.527813954</td><td>0.002208215</td><td>0.01690487</td></tr><tr><td>Mtor</td><td>0.748592671</td><td>0.000655819</td><td>0.0067544</td><td>Zfp953</td><td>0.867619616</td><td>0.001906639</td><td>0.015181636</td></tr><tr><td>Mtrex</td><td>0.75981622</td><td>0.00139274</td><td>0.012010479</td><td>Zfp955b</td><td>0.560194647</td><td>0.002471652</td><td>0.018365425</td></tr><tr><td>Mturn</td><td>1.228648765</td><td>7.83E-06</td><td>0.000193456</td><td>Zfp960</td><td>1.574405535</td><td>0.000877611</td><td>0.008499731</td></tr><tr><td>Mtus1</td><td>0.832543119</td><td>0.002369998</td><td>0.017827326</td><td>Zfp979</td><td>1.622243211</td><td>0.001107061</td><td>0.010203202</td></tr><tr><td>Mxd1</td><td>0.486586727</td><td>0.000537955</td><td>0.005790984</td><td>Zfp992</td><td>3.974343692</td><td>2.81E-12</td><td>3.45E-10</td></tr><tr><td>Mxi1</td><td>0.516856898</td><td>0.003369209</td><td>0.023150913</td><td>Zfx</td><td>0.744334256</td><td>0.000641617</td><td>0.006634899</td></tr><tr><td>Myh14</td><td>0.778467727</td><td>0.00309463</td><td>0.021786885</td><td>Zfyve1</td><td>0.478671111</td><td>0.006830571</td><td>0.039269548</td></tr><tr><td>Myh3</td><td>2.269862668</td><td>0.000140678</td><td>0.002022237</td><td>Zfyve26</td><td>0.766179081</td><td>2.47E-05</td><td>0.000499516</td></tr><tr><td>Myh9</td><td>0.892953583</td><td>3.84E-05</td><td>0.000714159</td><td>Zfyve27</td><td>0.469254717</td><td>0.001432483</td><td>0.012280373</td></tr><tr><td>Myo18a</td><td>0.837037062</td><td>0.000453644</td><td>0.005075953</td><td>Zhx1</td><td>1.010792441</td><td>0.001353351</td><td>0.011802372</td></tr><tr><td>Myo1e</td><td>0.912610495</td><td>0.002909548</td><td>0.02079569</td><td>Zik1</td><td>0.954791517</td><td>0.002546946</td><td>0.018762638</td></tr><tr><td>Myo6</td><td>0.645779715</td><td>0.000154296</td><td>0.002186394</td><td>Zkscan1</td><td>1.110999075</td><td>2.74E-08</td><td>1.55E-06</td></tr><tr><td>Myorg</td><td>0.691042804</td><td>0.008093329</td><td>0.044720316</td><td>Zkscan17</td><td>0.626678843</td><td>0.00226243</td><td>0.017182286</td></tr><tr><td>Myrf</td><td>0.865370512</td><td>7.22E-06</td><td>0.000181667</td><td>Zkscan5</td><td>0.579790523</td><td>0.001668962</td><td>0.013788628</td></tr><tr><td>N4bp2</td><td>0.676485261</td><td>0.007532815</td><td>0.042215475</td><td>Zkscan8</td><td>1.037881533</td><td>1.33E-07</td><td>6.08E-06</td></tr><tr><td>Naa15</td><td>0.615593222</td><td>0.000525493</td><td>0.005696481</td><td>Zmiz1</td><td>0.788524659</td><td>0.007860986</td><td>0.043666243</td></tr><tr><td>Naa30</td><td>0.70811594</td><td>0.000194001</td><td>0.002617555</td><td>Zmym2</td><td>0.702016667</td><td>0.001534122</td><td>0.012980981</td></tr><tr><td>Nab1</td><td>0.924806095</td><td>0.000330547</td><td>0.003954364</td><td>Zmym4</td><td>0.708902681</td><td>0.000674546</td><td>0.006892398</td></tr><tr><td>Nacad</td><td>0.749871723</td><td>0.004398556</td><td>0.028309809</td><td>Znfx1</td><td>0.907479835</td><td>1.84E-05</td><td>0.000392443</td></tr><tr><td>Nacc1</td><td>0.855424148</td><td>6.52E-06</td><td>0.00016901</td><td>Zpld1</td><td>7.352414438</td><td>5.52E-06</td><td>0.000146844</td></tr><tr><td>Nacc2</td><td>0.621977738</td><td>0.003976657</td><td>0.026219307</td><td>Zranb3</td><td>0.736608283</td><td>0.004093057</td><td>0.026799812</td></tr><tr><td>Nadk</td><td>0.579630972</td><td>0.002668385</td><td>0.019467576</td><td>Zrsr1</td><td>3.008359648</td><td>4.42E-49</td><td>7.60E-46</td></tr><tr><td>Nalcn</td><td>0.734565348</td><td>0.004278798</td><td>0.027766067</td><td>Zswim4</td><td>0.553749786</td><td>0.009223506</td><td>0.048892858</td></tr><tr><td>Nbas</td><td>0.986273116</td><td>2.36E-10</td><td>2.14E-08</td><td>Zswim5</td><td>0.792789322</td><td>0.001975936</td><td>0.015595458</td></tr><tr><td>Nbr1</td><td>1.017684202</td><td>3.56E-07</td><td>1.45E-05</td><td>Zyg11b</td><td>1.017152454</td><td>4.65E-07</td><td>1.82E-05</td></tr><tr><td>Ncam1</td><td>0.655126993</td><td>0.000110482</td><td>0.001673425</td><td>Zzz3</td><td>0.965643376</td><td>0.003248626</td><td>0.022535331</td></tr></table>
<table><caption>Supplementary Table 2</caption><thead><tr><th>Gene</th><th>Forward primer</th><th>Reverse primer</th></tr></thead><tbody><tr><td>Abtb2</td><td>ACCGAGTCCATGGAAATCCC</td><td>CAGGGCATCTAGCTGGAACA</td></tr><tr><td>Adam17</td><td>CTGCTTCCAAAAGGGCTCATA</td><td>AGGTTCAGCTCGTCTCTTCA</td></tr><tr><td>App</td><td>GAACTTGCCCAAAGCTGACAA</td><td>ATTGGCTGCTTCCTGTTCCA</td></tr><tr><td>Celsr2</td><td>AGCAATGACTGGGACAGCTA</td><td>TGGGTTCAGGTCACACACA</td></tr><tr><td>Chd4</td><td>GCAGACAGCAGTCTTCCTCTA</td><td>GACAGAGGAGCGCTCACTAA</td></tr><tr><td>Clic5</td><td>ACGGACTCAGCGACAACTAA</td><td>ACAGTTGCCAATGCTTTCCC</td></tr><tr><td>Cpd</td><td>TGATAACCCAGGTGTCCATGAA</td><td>AGCTCTCTTCCAACCACTTCA</td></tr><tr><td>CSPG4</td><td>GCAGAGGAGGTCTTGGTGAA</td><td>GAGGACATCTCGTGCTCATACA</td></tr><tr><td>Dlg2</td><td>GGTCCCTTCGAACCAATCAGAA</td><td>CCACTGTCCTTGCTCTTGTCA</td></tr><tr><td>Dnmt1</td><td>AGCCATTGGCCTGGAGATTA</td><td>GCAGCCTCCTCTTTTGCTTTA</td></tr><tr><td>Dnmt3a</td><td>CGCCAGAAGTGCAGAAACA</td><td>AATGAAGAGTGGGTGCTCCA</td></tr><tr><td>Elf1</td><td>CCAGAGCAGCGCAAGAGAAA</td><td>TTGGTGTAGTCGTCGGGGAA</td></tr><tr><td>Enpp6</td><td>AGCCAGGAGGAAAGTCTACA</td><td>GGCAGTAAGTTGGTCTGACA</td></tr><tr><td>Ezh1</td><td>TCTGGGGACAAAGACATGCA</td><td>GCTCATCTGTTGGCAGCTTTA</td></tr><tr><td>Gapdh</td><td>CAAGGTCATCCCAGAGCTGAA</td><td>CAGATCCACGACGGACACA</td></tr><tr><td>Gnptab</td><td>AGAACACAACCGAACCGACAA</td><td>AGCATGGGCACCTTAATGCA</td></tr><tr><td>Gpr17</td><td>CCCAGTCTCCTGTCCTTTCC</td><td>GTAGGGCTGCCTCCAGAC</td></tr><tr><td>Gpr37</td><td>CCTGCAAGATCGTGCCCTATA</td><td>ACAGTGCACATAAGGTGAAGGTA</td></tr><tr><td>Hdac1</td><td>CCGAAGAGAGTGGGGATGAAG</td><td>TCACAGGCAATGCGTTTGTC</td></tr><tr><td>Heg1</td><td>GCCCGGTTATATCCGAACTACA</td><td>CAGGGCAAAGGTGGTTTTCA</td></tr><tr><td>Hes5</td><td>AAGAGCCTGCACCAGGACTA</td><td>GTGCAGGGTCAGGAACTGTAC</td></tr><tr><td>Hipk3</td><td>CGGTTGTGGAGATGCTTTTCA</td><td>GTTTACCATGTGCTGCAGGAA</td></tr><tr><td>Id2</td><td>ACCCTGAACACGGACATCA</td><td>TCGACATAAGCTCAGAAGGGAA</td></tr><tr><td>Id4</td><td>CACTCACCGCGCTCAAC</td><td>CGGCAGAGAATGCTGTCAC</td></tr><tr><td>Igf2r</td><td>TCAACGATTCTGCTCAAGGAC</td><td>CAGGCATTGCACCACAGATA</td></tr><tr><td>Il17rb</td><td>TGGCAGCTGGGATCTACCTAA</td><td>GGCAGGAGCATGGTGGAAATA</td></tr><tr><td>Kcna6</td><td>CTAGCATCCCAGAGGAGCAA</td><td>TCGGGTACTCTTTGGATGCA</td></tr><tr><td>Lpin1</td><td>CTCTCTTGCCAACGTCAGCTA</td><td>ATCATTGGGGCCGTTCTTCA</td></tr><tr><td>Mag</td><td>CAGAGAGCCACTGCCTTCAA</td><td>CTGCACAGTGTGACTCCAGAA</td></tr><tr><td>Mbp</td><td>CCCTCACAGCGATCCAAGTA</td><td>CTCTGTGCCTTGGGAGGAA</td></tr><tr><td>Mfsd6</td><td>TTCTCCTCTTTTGCCCTGATCC</td><td>TGGGATCCTTTCTGCCAACA</td></tr><tr><td>Mobp</td><td>CAGGCTCTCCAAGAACCAGAA</td><td>TCACGCTTGGAGTTGAGGAA</td></tr><tr><td>Mog</td><td>ACACCTGCTTCTTCAGAGACC</td><td>CCGGGGTTGACCCAATAGAA</td></tr><tr><td>Mtmr10</td><td>AAGTACCCGGTGGTTAGAGTAC</td><td>GAGACGCTGGCTTTCAAGAA</td></tr><tr><td>Myrf</td><td>GCTGGAGAATTCCATGCCTA</td><td>ACAGGGATGTGGTAGGTGAA</td></tr><tr><td>Ncoa2</td><td>GTGTCATCGACAAGGATGCA</td><td>CCTTCCAGGTTCACAACGAA</td></tr><tr><td>Ndrg1</td><td>ACATGAACCCGAGCAACCTA</td><td>CATTGGCCGCTCAATCTCC</td></tr><tr><td>Ndrg2</td><td>CAAGCTGACAGAGGCTTTCAA</td><td>ATAGGCGAGTCATGCAGGAA</td></tr><tr><td>NKX2-2</td><td>CCAGCCTCATCCGTCTCA</td><td>CGGGCACGTTTCATCTTGTA</td></tr><tr><td>Olig1</td><td>CTGTATGAGCTGGTGGGTTACA</td><td>GAGAAGGGATGCGGTGGAA</td></tr><tr><td>Olig2</td><td>CTGGCGCGAAACTACATCC</td><td>CCCCGTAGATCTCGCTCAC</td></tr></tbody></table>
<table>
  <tr>
    <td>Opalin</td>
    <td>GATCCAGCGAAGAAGAACCA</td>
    <td>TGGGATTGTCATAGAGTTCTGAAA</td>
  </tr>
  <tr>
    <td>Pcdh1</td>
    <td>GAAGCCGAGCTGTCTGAGAA</td>
    <td>GCACCTTGGTCTGAGTCGTTA</td>
  </tr>
  <tr>
    <td>Pcdh9</td>
    <td>TTAAGTTGGTGCCCCCTCTCA</td>
    <td>CTGCATTCATTCCGGTGTCA</td>
  </tr>
  <tr>
    <td>Pcdhb11</td>
    <td>TGGCCACCTGATGGATGTTA</td>
    <td>CTCACCAGTCCTAGAGTCTCC</td>
  </tr>
  <tr>
    <td>Pcdhb15</td>
    <td>TGCTGCTGTTCGTTGGAGTA</td>
    <td>GTGTTCTTCAGGCACAAAGCA</td>
  </tr>
  <tr>
    <td>Pcdhb2</td>
    <td>CAATGCCCCGGTGTTTTCAA</td>
    <td>AGTAGCAACCTGGGATCCAAC</td>
  </tr>
  <tr>
    <td>Pcdhb20</td>
    <td>GGTGTGTTTCACAGGAGGTAC</td>
    <td>ATCAGGGTCATGGAGCTGAA</td>
  </tr>
  <tr>
    <td>Pcdhb22</td>
    <td>TCGCTCACCAATCCAATCCC</td>
    <td>TCCAGAGTCTCGGTCTCGAA</td>
  </tr>
  <tr>
    <td>Pcdhga12</td>
    <td>GAATGACAACGTCCCCGAAA</td>
    <td>GTGCTAGCTCCACTCCAGTA</td>
  </tr>
  <tr>
    <td>Pcdhga4</td>
    <td>ATCCTGGCTGATCTGGTCAA</td>
    <td>ACAGCTACCACCAGGTACAA</td>
  </tr>
  <tr>
    <td>Pcdhga5</td>
    <td>AGCCACTGTCACACTCACTA</td>
    <td>CAGTGTGTTGTGGTTGCCTA</td>
  </tr>
  <tr>
    <td>Pcdhga8</td>
    <td>TGCAGACATGCTCATTAACCA</td>
    <td>CTTGAGAGAAACGCCAGTCA</td>
  </tr>
  <tr>
    <td>Pcdhgb1</td>
    <td>GTGTTCAGCCAGGACACTTAC</td>
    <td>GCTGTCACTTGCAGCACTAA</td>
  </tr>
  <tr>
    <td>Pcdhgb4</td>
    <td>TGAGCAGAACCCGGAATACA</td>
    <td>AGGTGACACTTGAGCTGGAA</td>
  </tr>
  <tr>
    <td>Pcdhgb8</td>
    <td>GTGAGTGTCGCTGAGGAGAA</td>
    <td>GGTCTCTGGGCTTGAGAGAAA</td>
  </tr>
  <tr>
    <td>Pdgefra</td>
    <td>CAAAGGGAGGACGTTCAAGAC</td>
    <td>TGCGTCCATCTCCAGATTCA</td>
  </tr>
  <tr>
    <td>Pja2</td>
    <td>TGGCACTAGAAGAGCGCTTA</td>
    <td>ATTGGCCACCTCAACGTCTA</td>
  </tr>
  <tr>
    <td>Plp1</td>
    <td>TGTGGACATGAAGCTCTCAC</td>
    <td>AGAGGCAGTTCCATAGATGACA</td>
  </tr>
  <tr>
    <td>Ptpre</td>
    <td>CGATCCGAAAGTTCTGCATCC</td>
    <td>GTGAAGTCAGCTGTGAGAC</td>
  </tr>
  <tr>
    <td>Scd1</td>
    <td>AGGCCTGTACGGGATCATAC</td>
    <td>AGCGCTGGTCATGTAGTAGAA</td>
  </tr>
  <tr>
    <td>Sft2d2</td>
    <td>GAAGCGCATGTTTGAGCCTA</td>
    <td>CAGAACACAGGGTAAGTGCAAA</td>
  </tr>
  <tr>
    <td>Shroom2</td>
    <td>AAGTCCCCTTACCCAGAGTCA</td>
    <td>AATTGGTGGCCAAGGACACA</td>
  </tr>
  <tr>
    <td>Slc12a2</td>
    <td>AGGAGCATTCAAGCACAGCTA</td>
    <td>CCATATACAGAGCACTGGACACA</td>
  </tr>
  <tr>
    <td>Slc12a6</td>
    <td>GCATATGCGGCTGTCCAAAA</td>
    <td>ATGCTGGTCAAGCGTAGCA</td>
  </tr>
  <tr>
    <td>Slc22a23</td>
    <td>CGCACTGGTCTCATCCAAAA</td>
    <td>AGCGATATGGACTTTCCAGGTA</td>
  </tr>
  <tr>
    <td>Slc27a1</td>
    <td>GACCACCGGGCTTCCTA</td>
    <td>CTGTAGGAATGGTGGCCAAA</td>
  </tr>
  <tr>
    <td>Slc30a2</td>
    <td>ACTGGTGGCAGCCTATATCA</td>
    <td>CCCAAGACCAGGATGGAGAA</td>
  </tr>
  <tr>
    <td>Slc30a7</td>
    <td>CGGATTGGCAGCTTCTGTTA</td>
    <td>AGCCAGGACTTCTGCTCTAA</td>
  </tr>
  <tr>
    <td>Slc35e1</td>
    <td>CCATTCTGGGTGTCTTCCTGTA</td>
    <td>GTCTGACGTGGAGATGGGAA</td>
  </tr>
  <tr>
    <td>Slc38a2</td>
    <td>TTGCAGGCCACGCTATTTCA</td>
    <td>CGGGATGGCAGACAAAGGAA</td>
  </tr>
  <tr>
    <td>Slc39a9</td>
    <td>GCCCAGCAGTTCCAAAATCA</td>
    <td>TGCTGCTCCCAAAGCTACA</td>
  </tr>
  <tr>
    <td>Slc5a3</td>
    <td>CGCTACGAGTTGGCTTTGATT</td>
    <td>GTTGCAGCTAAGTCTAGTGAAGC</td>
  </tr>
  <tr>
    <td>Slc6a1</td>
    <td>CTACCTGATTGGCCTGTCTAACA</td>
    <td>TGCCGCTGGCAGAGTAATAA</td>
  </tr>
  <tr>
    <td>Slc9a6</td>
    <td>ACGCTGTTCACCTTCCAGAA</td>
    <td>TGGCAGCTCTTCCCAAGAAA</td>
  </tr>
  <tr>
    <td>Sox10</td>
    <td>ACCAGTACCCTCACCTCCA</td>
    <td>GCGCTTGTCACTTTCGTTCA</td>
  </tr>
  <tr>
    <td>Sox5</td>
    <td>CTCTGTCCCGGCAGCATTA</td>
    <td>TCTTGGATTGCCTTGGTGACA</td>
  </tr>
  <tr>
    <td>Sox6</td>
    <td>TCTGGACTCAGCCCTTTACA</td>
    <td>CATCTTTGCTCCAGGTGACA</td>
  </tr>
  <tr>
    <td>Tcf7l2</td>
    <td>GCACCGTAGGACAAATCCC</td>
    <td>TCCTGTCGTGATTGGGTACA</td>
  </tr>
  <tr>
    <td>Tet1</td>
    <td>AGATGGCTCCAGTTGCTTATCA</td>
    <td>ACGCCCCTCTTCATTTCCAA</td>
  </tr>
  <tr>
    <td>Tet2</td>
    <td>CTACATGGAGCTGAGCCAAA</td>
    <td>TTGGAGCAATGACAGTAGCC</td>
  </tr>
  <tr>
    <td>Tet3</td>
    <td>ACGCCAGAGAAGATCAAGCA</td>
    <td>GACAATCCACCCTTCAGAGACA</td>
  </tr>
  <tr>
    <td>Thrap3</td>
    <td>GAGGAAATGAACAAGAAGCAGCTAA</td>
    <td>AGGTTCCCGTGGACTTTTCA</td>
  </tr>
  <tr>
    <td>Tmed8</td>
    <td>TGGCTTCTGCTTCTGATCCA</td>
    <td>CCTTACTCGCTGGAGATACCA</td>
  </tr>
  <tr>
    <td>Uhrf1bp1</td>
    <td>TGGGACTCTGGCAGTTTCTAC</td>
    <td>CCTGATGGGGTTGGTCTTCA</td>
  </tr>
</table>
<table><caption>**Supplementary Table 2.** List of primers used for the Biomark study.</caption><tr><td>Usp6nl</td><td>TGGGCTCTTCTTCTTGAGATCC</td><td>ACCCCGTGCTCTGTGTTTTA</td></tr><tr><td>Wdr33</td><td>CAGGCACATAAGGAGGCGATTA</td><td>CCGTCATCAGAGCATGTAGCA</td></tr><tr><td>Wdr81</td><td>CGCCTGCTGACATCTTGTTA</td><td>CATTCAGTGGAGGGGTGTCA</td></tr><tr><td>Yipf6</td><td>CCTGTGGGGCCCATTGATAC</td><td>CCGCCATCATTCTTCCCATCA</td></tr><tr><td>Yy1</td><td>CAAGAACAATAGCTTGCCCTCA</td><td>GGTGTGCAGATGCTTTCTCA</td></tr><tr><td>Zbtb41</td><td>ATCCCGGTTTGCACGGTTA</td><td>TGAACTGACGACCACATATATCACA</td></tr><tr><td>Zdhhc2</td><td>CTGCCTTTTCATTGCTGCTACC</td><td>TTGGCTTGAGTATCAGGCAGAC</td></tr><tr><td>Zfp319</td><td>GGAATAAAGAGGCGGCAGAGAA</td><td>CAGGGTCCTGGCAATGCTAA</td></tr><tr><td>Zfp507</td><td>GGAACCACAGACGAGTCCATAA</td><td>GCTGCACACATACCCACAC</td></tr><tr><td>Zfp84</td><td>CCTGGATAGTGGAGCAAGCA</td><td>AGGCAAGAACTACCAACTCTTTCTA</td></tr><tr><td>Znfx1</td><td>CGGCTGGTAAAAGTGAACATCC</td><td>CAAAAGGCGGGCGATTTCA</td></tr></table>

<table><caption>**Supplementary Table 3**</caption><thead><tr><td>Gene</td><td>Forward primer</td><td>Reverse primer</td></tr></thead><tbody><tr><td>Gapdh</td><td>ACCCAGAAGACTGTGGATGG</td><td>CACATTGGGGGTAGGAACAC</td></tr><tr><td>Pja2</td><td>GCCTTGCCATCACTTCTTTC</td><td>GCAGATGCGTCAATAACTGC</td></tr><tr><td>Slc12a2</td><td>TTCCGCGTGAACTTCGTGG</td><td>TTGGTGTGGGTGTCATAGTAGT</td></tr><tr><td>Tet1</td><td>GAAGATAGTGTTCAGGGGGAAG</td><td>TACACGCTCACGAACCAAAC</td></tr><tr><td>Wdr33</td><td>TGATCTGGTCCCACCAATAG</td><td>TGACCAATCGTCTTCCTTCC</td></tr></tbody></table>

<caption>**Supplementary Table 3.** List of primers used for qRT-PCR.</caption>
Supplementary Figures:

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<figure><img src="image_72.png" /></figure>

**Supplementary Figure 1. Age-dependent decline of myelin repair after lesion.**

(a) Representative confocal image of coronal spinal cord sections from young adult (P60) mice stained for Fluoromyelin (green) and DAPI (blue) as nuclear counterstain. Unlesioned normal white matter (NWM) is shown as comparison for the 21 days post lesion (21dpl) recovery after lysolecithin injection. The white dotted line indicates the average lesion size after lysolecithin injection. Scale bar = 100µm. (b) Quantification of Fluoromyelin intensity measured at the lesion side at several time points after injection (7dpl, 14dpl and 21dpl). Measurements are expressed as percentage, relative to the levels of intensity detected in the unlesioned white matter (NWM). Data represent average Fluoromyelin intensity measures in at least 4 sections/mouse in n=4 mice. Error bars represent SEM (***p < 0.001, One-way ANOVA for time). (c) Representative confocal image of coronal spinal cord sections from older mice (P540) mice stained for Fluoromyelin (green) and DAPI (blue) as nuclear counterstain. White dotted line identifies lesion site. Scale bar = 100µm. (d) Quantification of Fluoromyelin intensity measured at the lesion side in at least 4 sections/mouse in n=5 mice, at the indicated time points after injection. Values expressed as percentage, relative to the levels of intensity detected in the unlesioned white matter (NWM). Error bars represent SEM (ns, One-way ANOVA for time). (e) Confocal images of coronal spinal cord sections from young and old mice stained for 5hmC (green) in OLIG2+ (red). Representative stainings in unlesioned (NWM) and lesioned areas after 14 days from injection (14dpl) are shown. White arrowheads indicate OLIG2+ cells with high 5hmC immunoreactivity. Scale bar = 50µm. (f) Quantification of the density of OLIG2+ cells per mm² in unlesioned and lesioned areas of the spinal cord of young and old mice. Data represent average number of OLIG2+ cells per mm² ± SEM for n=4 young and n=5 old mice (ns, Two-way ANOVA, for age and time after lesion). (g) Quantification of the number of proliferating OLIG2+ cells identified by Ki67 immunoreactivity at the indicated time points after lesion. Data are expressed as percentages in lesioned areas, compared to levels in NWM in young and old mice. The dotted line refers to the percentage of proliferating cells in unlesioned white matter at each age and serves as reference. Error bars represent SEM and values represent the average of 3 sections/mouse for n=4 young and n=5 old mice (**p < 0.01 and ***p < 0.001, One-way ANOVA, factor time).
a

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b

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c

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d

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e

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f

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g

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h

<figure><img src="image_80.png" /><figcaption>Supplementary Figure 2. Age-dependent decline of TET1 expression in OLIG2+ cells in the adult spinal cord during myelin repair after lysolecithin-induced demyelination.</figcaption></figure>

(a) Representative confocal image of coronal spinal cord sections from young adult (P60) mice stained for TET1 (green) and OLIG2 (red). White arrowheads indicate co-labeled cells. Scale bar = 50µm. (b) Data represent the average percentage of TET1 expressing OLIG2+ cells relative to the total population of OLIG2+ cells, in lesioned areas of the spinal cord at 7dpl, 14dpl and 21dpl in young mice. Dotted line refers to the percentage of OLIG2+ cells expressing TET1 in unlesioned tracts. Error bars represent SEM, 3 sections/mouse, n=4 mice (ns, One-way ANOVA, factor time after lesion). (c) Representative confocal image of coronal spinal cord sections from old adult (P540) mice stained for TET1 (green) and OLIG2 (red). White arrowheads indicate co-labeled cells in unlesioned (NWM) and lesioned (14dpl) spinal cord. Scale bar = 50µm. (d) Data represent the average percentage of TET1 expressing OLIG2+ cells relative to the total population of OLIG2+ cells at the indicated time points in old mice. Dotted line refers to the percentage of OLIG2+ cells expressing TET1 in unlesioned tracts. The average was calculated by counting 3 sections/mouse in n=5 mice. Error bar represent SEM (ns, One-way ANOVA, factor time after lesion). (e) Representative confocal image of coronal spinal cord sections from young adult (P60) mice stained for TET2 (green) and OLIG2 (red). White arrowheads indicate co-labeled cells. Scale bar = 50µm. (f) Data represent the average percentage of TET2 expressing OLIG2+ cells relative to the total population of OLIG2+ cells, in lesioned areas of the spinal cord at 7dpl, 14dpl and 21dpl in young mice. Dotted line refers to the percentage of OLIG2+ cells expressing TET2 in unlesioned tracts. Error bars represent SEM, 3 sections/mouse, n=4 mice (ns, One-way ANOVA, factor time after lesion). (g) Representative confocal image of coronal spinal cord sections from old mice (P540) stained for TET2 (green) and OLIG2 (red). Scale bar = 50µm. (h) Data represent the average percentage of TET2 expressing OLIG2+ cells relative to the total population of OLIG2+ cells, in lesioned areas of the spinal cord at 7dpl, 14dpl and 21dpl in old mice. Dotted line refers to the percentage of OLIG2+ cells expressing TET2 in unlesioned tracts. The average was calculated by counting 3 sections/mouse in n=5 mice. Error bar represent SEM (ns, One-way ANOVA, factor time after lesion).
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<figure><img src="image_84.png" /></figure>

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<figure><img src="image_90.png" /><figcaption>Supplementary Figure 3. Ablation of *Tet2* during development is compatible with normal myelination in the adult central nervous system.</figcaption></figure>

(a) Photograph of young adult wild type (*Olig1<sup>+/+</sup>;*Tet2<sup>fl/fl</sup>) and Tet2 mutant (*Olig1<sup>cre/+</sup>;*Tet2<sup>fl/fl</sup>) mice at P60 reveals no difference in body size. (b) Kaplan-Meier survival curve and (c) body weight for *Olig1<sup>+/+</sup>;*Tet2<sup>fl/fl</sup> (n=16) and *Olig1<sup>cre/+</sup>;*Tet2<sup>fl/fl</sup> (n=10) mice. Error bars represent SEM. (d) Quantification of the percentage of OLIG2+ cells expressing TET1, TET2 or TET3 in the corpus callosum of P60 controls (*Olig1<sup>+/+</sup>;*Tet2<sup>fl/fl</sup>) and mutant (*Olig1<sup>cre/+</sup>;*Tet2<sup>fl/fl</sup>) mice. TET2 in oligodendroglial cells, without increased expression of TET1 or TET3. Data represent the percentage of TET-expressing OLIG2+ cells quantified in 3 sections/mouse in n=7 control mice and n=5 Tet2 mutants. Error bars represent SEM (p=0.5762 for TET1, ***p=0.0004 for TET2, p=0.9300 for TET3, Student's t-test two-tailed). (e) Representative confocal images of P60 coronal spinal cord sections from controls and mutant mice stained for OLIG2 (green), CC1 (red), MBP (white), DAPI (blue) as nuclear counterstain. Scale bar = 500µm. (f) Quantification of OLIG2+ and CC1+ cell density in the white matter spinal cord of controls and mutant mice at P60. Data represent average numbers of OLIG2+ and CC1+ cells per mm² quantified in n=3 control mice and n=5 Tet2 mutants. Error bars represent SEM. (p=0.3788 for OLIG2 and p=0.5677 for CC1, Student's t-test two-tailed). (g) Quantification of the average MBP+ area, relative to the total white matter area of coronal spinal cord sections. Error bars represent SEM for n=3 control mice and n=5 Tet2 mutants (p=0.5512, Student's t-test two-tailed). (h) Representative confocal images of P60 corpus callosum in coronal brain sections from mice of the two genotypes, stained for OLIG2 (green), CC1 (red) and MBP (white). DAPI (blue) as nuclear counterstain. Scale bar = 500µm. (i) Quantification of OLIG2+ and CC1+ cell density in the corpus callosum of controls and mutant mice at P60. Data represent average numbers of OLIG2+ and CC1+ cells per mm² quantified in n=3 control mice and n=5 Tet2 mutants. Error bars represent SEM (p=0.2043 for OLIG2, p=0.1082 for CC1, Student's t-test two-tailed). (j) Quantification of the average MBP+ stained area in the corpus callosum relative to the entire extent of the corpus callosum in each section. Error bars represent SEM for n=3 control mice and n=5 Tet2 mutants (p=0.7161, Student's t-test two-tailed).
<figure><img src="image_91.png" /><figcaption>**Supplementary Figure 4. Cell-specificity of *Tet1* ablation in *Olig1<sup>cre</sup>;*Tet1<sup>fl/fl</sup> adult mice.**</figcaption></figure>

(a) Representative confocal images of P60 coronal spinal cord sections from control (Olig1<sup>+/+</sup>; Tet1<sup>fl/fl</sup>) or Tet1 mutant (Olig1<sup>cre/+</sup>; Tet1<sup>fl/fl</sup>) mice, stained for TET1 (green) and OLIG2 (red). DAPI (blue) as nuclear counterstain. White arrowheads indicate co-labeled cells. Scale bar = 50µm. (b) Representative confocal images of P60 coronal spinal cord sections from control (Olig1<sup>+/+</sup>; Tet2<sup>fl/fl</sup>) or Tet2 mutant (Olig1<sup>cre/+</sup>; Tet2<sup>fl/fl</sup>) mice, stained for TET2 (green), OLIG2 (red) and DAPI (blue). White arrowheads indicate co-labeled cells. Scale bar = 50µm. (c) Representative confocal images of P60 coronal spinal cord sections from control (Olig1<sup>+/+</sup>; Tet1<sup>fl/fl</sup>) or Tet1 mutant (Olig1<sup>cre/+</sup>; Tet1<sup>fl/fl</sup>) mice, stained for TET1 (green) and the neuronal marker ISLET1 (red). White arrowheads indicate co-labeled cells. Scale bar = 50µm. (d) Bar graphs representing the percentage of ISLET1+ cells relative to total number of DAPI+ nuclei (left) and the percentage of TET1 expressing ISLET1+ cells in mice of the two genotypes (right). Error bar represent SEM for n=4 control mice and n=3 *Tet1* mutants (p=0.7223, p=0.6685, Student's t-test two-tailed). (e) Representative confocal images of P60 coronal sections from control (Olig1<sup>+/+</sup>; Tet1<sup>fl/fl</sup>) or Tet1 mutant (Olig1<sup>cre/+</sup>; Tet1<sup>fl/fl</sup>) mice, stained for TET1 (green), GFAP (red) and DAPI (blue). White arrowheads indicate co-labeled cells. Scale bar = 50µm. (f) Bar graphs represent the average intensity of GFAP+ per area in mice of the two genotypes (left) and the number of TET1 expressing cells per given GFAP+ area in controls and mutants (right). Error bar represent SEM for n=3 control mice and n=4 *Tet1* mutants (p=0.4448, p>0.9999, Student's t-test two-tailed).
<figure><img src="image_92.png" /><figcaption>Supplementary Figure 5. Ablation of *Tet1* during development is compatible with normal myelination in the adult central nervous system.</figcaption></figure>

(a) Representative high-magnification confocal micrograph of the ventral portion of the spinal cord in coronal sections from postnatal day 14 (P14) controls (*Olig1⁺/⁺;Tet1fl/fl*) and *Tet1* mutant (*Olig1cre/⁺;Tet1fl/fl*) mice stained for OLIG2 (green), CC1 (red), MBP (white), DAPI (blue). Scale bar = 100µm. (b) Quantification of OLIG2+ and CC1+ cell density in mice of the indicated genotypes at the P14 developmental time point. Data represent average numbers of OLIG2+ or CC1+ cells per mm². Error bars represent SEM for n=4 mice (p=0.4507 for OLIG2, p=0.9815 for CC1, Student's t-test two-tailed).

(c) Quantification of MBP+ area in the same section, referred as percentage of the total white matter (WM) region in the spinal cord. Error bar represent SEM for n=4 mice (p=0.0596, Student's t-test two-tailed). (d) Representative electron micrographs of myelinated axons in the P14 ventral white matter spinal cord from *Olig1⁺/⁺;Tet1fl/fl* and *Olig1cre/⁺;Tet1fl/fl*. Scale bar = 5µm. (e) Percentage of myelinated axons referred to the total number of axons per measured area. Error bars represent SEM for n=4 mice (p=0.2680, Student's t-test two-tailed). (f) Scatter plot of the g-ratio calculated in the spinal cord of P14 control (black circles) and *Tet1* mutants (red circles) and referred by axonal diameter. Quantification in 80-195 axons per mouse, for n=4 mice (non-linear regression, p=0.0662, comparison of slopes with sum-of-squares F Test). (g) Representative electron micrographs of myelinated axons in the P14 optic nerve from mice of the indicated genotype. Scale bar = 5µm. (h) Percentage of myelinated axons referred to the total number of axons per measured area. Error bars represent SEM for n=4 control mice and n=3 *Tet1* mutants (p=0.4832, Student's t-test two-tailed). (i) Scatter plot of the g-ratio calculated in the optic nerve of control (black circles) and *Tet1* mutant (red circles) mice and referred by axonal diameter. Quantification in 93-170 axons for mouse and n=4 control mice and n=3 *Tet1* mutants (non-linear regression, p=0.4335, comparison of slopes with sum-of-squares F Test).
<figure><img src="image_93.png" /><figcaption>Supplementary Figure 6. Defective myelin repair in the spinal cord of adult mice with either constitutive or inducible ablation of *Tet1* in the oligodendrocyte lineage.</figcaption></figure>

(a) Quantification of MBP⁺ areas in the spinal cord of control (Olig1⁺/⁺;Tet1fl/fl and Olig1⁺/⁺;Tet2fl/fl), Tet1 (Olig1cre/⁺;Tet1fl/fl) and Tet2 mutant (Olig1cre/⁺;Tet2fl/fl) mice at 14 days post lesion. Data expressed as percentage of MBP⁺ area relative to the unlesioned white matter (NWM) area. Error bars represent SEM for n=3 control mice, n=4 Tet1 mutants and n=5 control and Tet2 mutants (\*\*p=0.0075 for Tet1 mutants, p=0.9388 for Tet2 mutants, Student's t-test two-tailed). (b) Quantification of the percentage of proliferating OLIG2⁺ cells identified by KI67 immunoreactivity in an average of 3 spinal cord sections/mouse from 3 mice for each of the indicated genotypes at 4dpl and 14dpl. Dotted line refers to the percentage of proliferating OLIG2⁺ cells in unlesioned tracts (normal white matter, NWM). Error bars represent SEM for n=3 control mice and n=4 Tet1 mutants (ns, Two-way ANOVA, for age and time after lesion). (c) Quantification of the percentage of OLIG2⁺ cells relative to total DAPI⁺ nuclei (left) and of the percentage of CC1⁺ cells relative to total OLIG2⁺ cells (right) in sections of the spinal cord from mice of the indicated genotypes, stained 14 days after lesion. Error bars represent SEM for n=3 control mice and n=4 Tet1 mutants (p=0.9931 for OLIG2, p=0.9405 for CC1, Student's t-test two-tailed). (d) Quantification of TET1 expressing OLIG2⁺ cells in unlesioned controls (Pdgfra-creER(T)⁺/⁺;Tet1fl/fl) and inducible (Pdgfra-creER(T)⁺/⁺;Tet1fl/fl) mutant spinal cords, after tamoxifen induction. Data represent the average percentage of TET1 expressing cells relative to total OLIG2⁺ cells (left) and to DAPI⁺ nuclei (right). Error bars represent SEM for n=3 control mice and n=5 inducible Tet1 mutants (\*\*\*p < 0.0001 for OLIG2⁺ cells, p=0.1845 for DAPI⁺ cells, Student's t-test two-tailed). (e) Quantification of TET1 expressing OLIG2⁺ cells in lesioned controls (Pdgfra-creER(T)⁺/⁺;Tet1fl/fl) and inducible mutant (Pdgfra-creER(T)⁺/⁺;Tet1fl/fl) spinal cords, stained 14 days post lesion. Data represent average percentage of OLIG2⁺ cells relative to total DAPI⁺ nuclei (left) and of CC1⁺ cells relative to total OLIG2⁺ cells. Error bars represent SEM for n=3 control mice and n=5 inducible Tet1 mutants (p=0.5478 for OLIG2, p=0.7003 for CC1, Student's t-test two-tailed). (f) Percentage of MBP⁺ area relative to total white matter (WM) in lesioned spinal cord assessed at 14dpl in mice of the indicated genotype, after tamoxifen induction. Error bars represent SEM for n=3 control mice and n=5 inducible Tet1 mutants (\*\*\*p < 0.0001, Student's t-test two-tailed). (g) Quantification of OLIG2⁺ cells also expressing SLC12A2 in lesioned spinal cord at the 14dpl time point in controls and inducible knockout mice, after tamoxifen gavage. Dotted line refers to the percentage of SLC12A2 expressing OLIG2⁺ cells in unlesioned tracts (NWM). Error bars: SEM for n=3 control mice and n=5 inducible Tet1 mutants (\*\*\*p=0.0001, Student's t-test two-tailed).
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<figure><img src="image_99.png" /><figcaption>Supplementary Figure 7. Characterization of cells sorted from adult reporter mice.</figcaption></figure>

(a) Adult (P60) *Pdgfra-H2BEGFP* reporter mice were used to perform a Percoll gradient isolation, in order to discard blood vessels and meninges and enrich for oligodendroglial lineage cells prior to fluorescence activated cell-sorting. (b) Immunofluorescence of sorted P60 *Pdgfra-H2BEGFP* cells (green), stained for the progenitor markers PDGFRα (red) or NG2 (red) 12 hours after plating. DAPI (blue) as nuclear counterstain. Scale bar = 100μm. Quantification from three independent experiments confirms that the majority of the sorted cells express the PDGFRα and NG2 markers. (c) Heatmap of the relative expression levels of the indicated cell-specific transcripts in three independent preparation of cells sorted from young adults (aOPC) or from P540 old mice (oOPC). Note the high expression of oligodendroglial lineage markers. (d) Adult (P60) *Plp-EGFP* reporter mice were used to perform a Percoll gradient isolation, in order to discard blood vessels and meninges and enrich for oligodendroglial lineage cells prior to fluorescence activated cell-sorting. (e) Immunocytochemistry of sorted P60 *Plp-EGFP* cells (green), stained for the mature markers MBP (red) and MOG (red). DAPI (blue) as nuclear counterstain. Scale bar = 100μm. Quantification from three independent experiments confirms that the majority of the *Plp-EGFP* sorted cells are mature OL, with high levels of MBP and MOG, and lacking the progenitor markers PDGFRα and NG2. (f) Heatmap of the relative expression levels of the indicated cell-specific transcripts in three independent preparation of P60 OL sorted from adult *Plp-EGFP* mice (aOL), identifying the enriched expression of myelin markers.
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<figure><img src="image_105.png" /><figcaption>Supplementary Figure 8. Quality control of Reduced Representation Hydroxymethylation Profiling of adult progenitors and oligodendrocytes sorted from reporter mice.</figcaption></figure>

(a) Average number of CpGs detected in each of the 6 independent biological samples identified by the RRHP analysis. White bar graph refers to the number of CpGs in the aOPC samples prepared from sorted *Pdgfra-H2BEGFP* cells. Gray bar graph refers to number of CpGs in aOL sorted from *Plp-EGFP* mice. Error bars represent SEM for n=3 *Pdgfra-H2BEGFP* and n=3 *Plp-EGFP* replicates (p=0.0576, Student's t-test two-tailed). (b) Histograms showing the overall CpG hydroxymethylation coverage in each sample of aOPCs (pdgfra2mn1, mn2, mn3) and aOLs (plp2mn1, mn2, mn3). As expected, the shape of the curve reflecting the overall distribution differs between aOPCs and aOLs, with the latter showing higher levels of DNA hydroxymethylation. (c) Correlation plot between gene size and number of hyper-hydroxymethylated CpGs at gene body regions. All the differentially expressed genes (up- and down-regulated) are shown (gray). Three examples of TET1-target genes are shown: *Slc12a2* (red), *Slc9a6* (pink) and *Slc22a23* (orange) in the enlargement of hyper-hydroxymethylated CpGs for genes under 200,000bp. Linear regression curve is in grey.
a

P60 spinal cord

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b

P60 spinal cord

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c

P60 spinal cord

<figure><img src="image_108.png" /><figcaption>**Supplementary Figure 9. Uncropped western blot gels.**</figcaption></figure>

(a-c) Full western blot of protein extract from P60 spinal cord of control (n=3) and *Tet1* mutants (n=3) stained for CNPase (a), GAPDH (b) and MBP (c). Molecular weight indicated on the left.