# NEURL1 wt Allele

National Cancer Institute

## Source

National Cancer Institute. NEURL1 wt Allele. NCI Thesaurus. Code C52088.

Human NEURL1 wild-type allele is located in the vicinity of 10q24.33 and is approximately 98 kb in length. This allele, which encodes E3 ubiquitin-protein ligase NEURL1 protein, plays a role in the regulation of proteasome-mediated protein degradation. The gene exhibits loss of heterozygosity in astrocytomas.