A dentifrice containing a siliceous polishing material and binding or gelling agent including resinous poly(ethylene oxide). The polishing agent flocculates in the presence of the resinous poly(ethylene oxide) and provides the dentifrice with desirable stain removal effectiveness without unduly raising dentin abrasion. Foaming character is also achieved when a polyoxyethylene-polyoxypropylene block copolymer and xanthan are present.

This invention relates to a dentifrice which provides effective stain 
removal. 
In ancestor applications, Ser. Nos. 277,774 and 299,684, dentifrices are 
described which provide excellent foaming with the use of the nonionic 
surface active agent block copolymer of polyoxyethylene-polyoxypropylene 
with xanthan as gelling or binding agent in which resinous poly(ethylene 
oxide) may also be present. The dentifrice thereof typically contains a 
dentally acceptable polishing agent such as a siliceous material; for 
instance, colloidal silica or synthetic alkali metal aluminosilicate 
complex, that is, material in which silica contains combined alumina. 
Based upon prior art considerations, as disclosed in U.S. Pat. No. 
3,020,230 to Smith, wherein silica material is stated to coagulate or 
flocculate in the presence of resinous poly(ethylene oxide) in order to 
precipitate it from a liquid suspension, one skilled in the dentifrice art 
would not have been led to use silica materials in a dentifrice containing 
resinous poly(ethylene oxide). Indeed, in U.S. Pat. No. 2,991,229 to 
Ivison, polishing agents or abrasives disclosed in a toothpaste containing 
poly(ethylene oxide) were "tricalcium phosphate, dicalcium phosphate and 
calcium carbonate and the like;" but not silica materials. 
It is an advantage of the present invention that a dentifrice is provided 
with improved stain removal which has acceptable cosmetic rheology and 
dentin abrasion characteristics. 
It is a further advantage that desirable foaming is achieved with inclusion 
of polyoxyethylene-poly oxypropylene block copolymer and xanthan in the 
dentifrice. 
Further advantages will be apparent from consideration of the following 
disclosure. 
In accordance with certain of its aspects, this invention relates to a 
dentifrice comprising about 20-80% by weight of a liquid humectant 
vehicle, about 5-50% by weight of a siliceous polishing material and about 
0.05-5% by weight of a resinous poly(ethylene oxide), said dentifrice 
containing flocculated particles of said siliceous polishing agent in the 
presence of said poly(ethylene oxide). 
The proportion of the siliceous polishing agent content is in the range 
from 5% to 50% by weight of the dentifrice, preferably from 10% to 30% 
such as from 10% to 25%. One such polishing agent is a complex alkali 
metal aluminosilicate having a refractive index of from 1.44 to 1.47 and 
containing at least 70% silica, up to 10% alumina, such as about 0.1-10% 
e.g. about 0.1-3%, preferably up to about 20% of moisture, such as about 
0.5-10%; and up to about 10% of alkali metal oxide. Typically, this 
material has a particle size in the range from 1 to 35 microns, preferably 
from 2 to 20 microns, e.g. 2 to 4 microns. The preferred moisture content 
is from 10% to 20% measured by ignition at 1000.degree. C. and the typical 
content of alkali metal oxide is from 5% to 10%. Generally, the polishing 
agent has a loose bulk density of up to 0.2 g/cc, such as from 0.07 to 
0.12 g/cc. Another suitable type of polishing agent is porous amorphous 
silicic anhydride having an average particle size preferably below 20 
microns and above 1 micron, a surface area of at least 200 m.sup.2 /g, 
preferably at least 300 m.sup.2 /g, and a bulk density of at least 0.15 
g/cm.sup.3, preferably at least 0.30 g/cm.sup.3, such as a dehydrated 
silica hydrogel (i.e. a xerogel), preferably of the well known regular 
density or intermediate density type. Examples of such amorphous silicic 
anhydride polishing agents are "Syloid 63", "Syloid 72", and "Syloid 74" 
(SYLOID is a trade mark) which are described in "The Davison Family of 
Syloid Silicas" published by their manufacturer, Grace, Davison Chemical 
Company. "Santocel 100" of Monsanto (SANTOCEL is a trade mark), is also a 
suitable dental abrasive. "Syloid 72" has an average particle size of 
about 4 microns, a surface area of about 340 m.sup.2 /g bulk density of 
about 1.77 g/cm.sup.3. For "Syloid 63" the corresponding figures are about 
9 microns, about 675 m.sup.2 /g and about 0.4 g/cm.sup.3. A grade of 
"Santocel 100" has a surface area of about 239 m.sup.2 /g and a bulk 
density of about 0.24 g/cm.sup.3. These amorphous silicic anhydrides may 
be used singly or in mixtures. 
Resinous poly(ethylene oxide) has been disclosed as a dentifrice gelling or 
binding agent in U.S. Pat. No. 2,991,229 to Ivison. Its presence smoothed 
the texture of the dentifrice; indeed, the dentrifrice of the present 
invention has a smooth texture even though flocculated particles from the 
siliceous polishing material are present. 
The poly(ethylene oxides) employed in this invention are solid, colorless, 
water-soluble resins. They appear to form homogeneous systems in water in 
all proportions, although the relatively higher molecular weight ethylene 
oxide polymers merely swell on the addition of small amounts of water. On 
the addition of greater amounts of water, the polymers pass into solution. 
The water solutions are viscous, the viscosity increasing both with the 
concentration of the polymer in the solution and the reduced viscosity of 
the polymer. The ethylene oxide polymers employed in this invention show 
little change in melting point with reduced viscosity (an indication of 
increased molecular weight) and the melting point, as measured by change 
in stiffness with temperature, was found to be about 
65.degree..+-.2.degree. C. throughout the range of reduced viscosities of 
from about 1.0 to about 10, and greater. These polymers, upon X-ray 
examination, disclose a crystalline structure similar to that exhibited by 
polyethylene. The crystallization temperature, as determined from 
measuring the break in the cooling curve, is about 55.degree. C. To 
facilitate the understanding of the instant invention, various terms will 
be defined. At the outset it should be noted that the word "poly(ethylene 
oxide)" as used throughout the specification and claims refers to ethylene 
oxide polymers which have a reduced viscosity in acetonitrile of at least 
0.5 and upwards to 75, and higher. 
Unless otherwise stated, by the term "reduced viscosity," as used herein, 
is meant a value obtained by dividing the specific viscosity of the 
concentration of the ethylene oxide polymer in the solution, the 
concentration being measured in grams of polymer per 100 milliliters of 
solvent at a given temperature, and is regarded as a measure of molecular 
weight. The specific viscosity is obtained by dividing the difference 
between the viscosity of the solution and the viscosity of the solvent by 
the viscosity of the solvent. The reduced viscosities herein referred to 
are measured at a concentration of 0.2 grams of poly(ethylene oxide) in 
100 milliliters of acetonitrile at 30.degree. C. (unless stated 
otherwise). 
Granular poly(ethylene oxide) results from the suspension polymerization of 
an agitated reaction mixture comprising ethylene oxide in contact with a 
polymerization catalyst therefor and in the presence of an inert organic 
diluent, e.g., heptane, in which ethylene oxide is soluble and the 
resulting poly(ethylene oxide) is insoluble. Granular poly(ethylene oxide) 
thus produced is obtained in a finely-divided solid particle state and 
resembles finely-divided sand in particle size. Unlike the granular 
poly(ethylene oxide) resulting from the suspension polymerization process, 
the bulk and solution polymerization processes yield a polymer which is a 
substantially homogeneous mass either conforming to the shape of the 
reaction vessel or, after driving off the organic medium, for example, by 
mechanical extrusion, e.g. Marshall Mill (under vaccum and at slightly 
elevated temperatures), resembles layers or sheets. This polymer 
subsequently can be reduced in particle size, for example, by dicing or 
the like. 
The term "granular" refers to the particle size of the ethylene oxide 
polymers prepared by suspension polymerization. A granular product is one 
which is in a free-flowing state and comprises particles averaging less 
than 5 mesh in size (U.S. Standard Size Sieve). 
The poly(ethylene oxide) comprises about 0.05-5% by weight of the 
dentifrice, preferably about 0.1-1.5%. 
In the dentifrice, the siliceous polishing agent flocculates in situ in the 
presence of the poly(ethylene oxide). The flocculated particles typically 
may agglomerate with each other and have apparent particle sizes up to 
about 250 microns or more, typically about 44 to 177 microns; in other 
words, the flocculated particles typically pass through a screen of U.S. 
Sieve No. 80 and are retained on a screen on U.S. Sieve No. 325. 
In spite of the presence of the flocculated particles the dentifrice is 
readily formulated to have a desirable appearance and a rheological 
texture without an undue "lumpy" appearance or "gritty" feel. 
The liquid vehicle of the dentifrice comprises water, humectant or mixtures 
thereof in amount of about 20-80%, preferably about 30-60%. When a 
substantially visually clear gel is desired, water is generally not 
present in amount above about 10% typically about 2-5%. When the 
dentifrice is opacified, greater amounts of water may be present. Typical 
humectants include sorbitol (as 70% aqueous solution), glycerine, 
maltitol, xylitol, polyethylene glycol 400 and polyethylene glycol 600. 
Most preferably the dentifrice contains about 25-50% maltitol. Maltitol 
may assist in improving stain removal when present in the dentifrice of 
the invention. It is noted that maltitol is disclosed as a dentifrice 
ingredient in Japanese Patent Publications 73/10241 and 65/15120. 
The liquid vehicle and gelling agent including resinous poly(ethylene 
oxide) and other components of the dentifrice are proportioned to form a 
cream or gel mass of desired consistency which is extrudible from an 
aerosol or pump container or a collapsible tube (for example aluminum, 
lead or plastic). 
In addition to the resinous poly(ethylene oxide), further gelling or 
binding agent such as sodium carboxymethyl cellulose, Irish moss, xanthan 
and the like may be present in amount of about 0.5-7%. Xanthan is 
preferred. The total amount of gelling or binding agent in the dentifrice 
can be about 0.1-12% by weight. 
Xanthan gum is a fermentation product prepared by action of the bacteria of 
the genus Xanthomonas upon carbohydrates. Four species of Xanthomonas, 
viz. X. campetris. X. phaseoli, X. malvocearum, and X. carotae are 
reported in the literature to be the most efficient gum producers. 
Although the exact chemical structure is not determined, it is generally 
accepted to be a heteropolysaccharide with a molecular weight of several 
million. It contains D-glucose, D-mannose and D-glucoronic acid in molar 
ratio of 2.8:3:2.0. The molecule contains 4.7% acetyl and about 3% 
pyruvate. The proposed chemical structure configuration can be found in 
McNeely and Kang, Industrial Gums, Ed. R. L. Whistler, Ch XXI, 2nd 
Edition, New York, 1973. The procedure for growing, isolating and 
purifying the xanthan gum is found in Manufacturing Chemist, May 1960, 
pages 206-208 (including mention at page 208 of potential use of gums 
therein described for formulating toothpastes). 
Use of special grades of xanthan gum, such as described in U.S. Pat. No. 
4,263,399 are within the scope of this invention. A grade described in 
U.S. Pat. No. 4,263,399 is a xanthan gum in which up to about 1.6% of the 
carboxyl groups are bound to calcium and the remaining carboxyl groups are 
bound to sodium, potassium, a mixture of sodium and potassium or other 
non-calcium cations. 
The dentifrice may contain an anionic, nonionic, cationic or amphoteric 
surface active agent to achieve increased prophylactic action, assist in 
achieving thorough and complete dispersion of the instant compositions in 
the oral cavity and render the instant compositions more cosmetically 
acceptable. 
A preferred surface active agent is a nonionic block copolymer containing 
polyoxyethylene and polyoxypropylene. Such block copolymers are available 
from Wyandotte Chemicals Corp. under the trade mark "Pluronic". They may 
be liquid, paste, or solid and are generally chemically defined in terms 
of the molecular weight of the polyoxypropylene hydrophobic moiety and the 
percent by weight of the polyoxyethylene hydrophilic moiety. 
The following block copolymers are available from Wyandotte: 
______________________________________ 
PLURONIC PHYSICAL HYDRO- MOL. WT. 
NUMBER CHARACTER PHIL HYDROPROBE 
______________________________________ 
L 121 LIQUID 10 4000 
L 101 LIQUID 10 3250 
L 81 LIQUID 10 2250 
L 61 LIQUID 10 1750 
L 31 LIQUID 10 950 
L 122 LIQUID 20 4000 
L 92 LIQUID 20 2750 
L 72 LIQUID 20 2050 
L 52 LIQUID 20 1750 
L 42 LIQUID 20 1200 
P 123 PASTE 30 4000 
P 103 PASTE 30 3250 
L 63 LIQUID 30 1750 
L 43 LIQUID 30 1200 
P 104 PASTE 40 3250 
P 94 PASTE 40 2750 
P 84 PASTE 40 2250 
L 64 LIQUID 40 1750 
L 44 LIQUID 40 1200 
P 105 PASTE 50 3250 
P 85 PASTE 50 2250 
P 75 PASTE 50 2050 
P 65 PASTE 50 1750 
L 35 LIQUID 50 950 
F 127 SOLID 70 4000 
F 87 SOLID 70 2250 
F 77 SOLID 70 2050 
F 108 SOLID 80 3250 
F 98 SOLID 80 2750 
F 88 SOLID 80 2250 
F 68 SOLID 80 1750 
F 38 SOLID 80 950 
______________________________________ 
The preferred nonionic block copolymers are solid (or flake) materials and 
the most preferred are Pluronic 108 (80% polyoxyethylene: 3250 molecular 
weight polyoxypropylene) and F 87 (70% polyoxyethylene: 2250 molecular 
weight polyoxypropylene). 
Other nonionic surface active agents which may be employed include 
condensates of sorbitan monosterate with approximately 20 moles of 
ethylene oxide. Amphoteric agents include quaternized imidazole 
derivatives which are available under the trademark "Miranol" such as 
Miranol C.sub.2 M. Suitable types of anionic detergents are water-soluble 
salts of higher fatty acid monoglyceride monosulphates, such as the sodium 
salt of the monosulphated monoglyceride of hydrogenated coconut oil fatty 
acids, higher alkyll sulphates, such as sodium lauryl sulphate, alkyl aryl 
sulphonates, such as sodium dodecyl benzene sulphonate, olefin 
sulphonates, such as sodium olefin sulphonate in which the olefin group 
contains 12-21 carbon atoms, higher alkyl sulphoacetates, higher fatty 
acid ester of 1,2-dihydroxy propane sulphonates, and the substantially 
saturated higher aliphatic acyl amides of lower aliphatic amino 
carboxyllic acid compounds, such as those having 12-16 carbons in the 
fatty acid, alkyl or acyl radicals, and the like. Examples of the last 
mentioned amides are N-lauroyl sarcosine and the sodium, potassium, and 
ethanolamine salts of N-lauroyl, N-myristoyl or N-palmitoyl sarcosine, 
which could be substantially free from soap or similar higher fatty acid 
material which tends to substantially reduce the effect of these 
compounds. The use of these sarcosine compounds in dentifrice compositions 
of the present invention is particularly advantageous since these 
materials exhibit a prolonged and marked effect in the inhibition of acid 
formation in the oral cavity due to carbohydrates breakdown in adition to 
exerting some reduction in the solubility of tooth enamel in acid 
solution. 
Cationic surface active germicides and antibacterial compounds such as 
di-isobutylphenoxyethoxyethyl dimethyl benzyl ammonium chloride, benzyl 
dimethyl stearyl ammonium chloride, tertiary amines having one fatty alkyl 
group (of from 12-18 carbon atoms) and two (poly)oxyethylene groups 
attached to the nitrogen (typically containing a total of from about 2 to 
50 ethanoxy groups per molecule) and salts thereof with acids, and 
compounds of the structure. 
##STR1## 
where R is a fatty alkyl group containing from about 12 to 18 carbon 
atoms, and x, y and z total 3 or higher, as well as salts thereof with 
mineral or organic acids, may also be used. It is preferred to use from 
about 0.05 to 5% by weight of the foregoing surface-active materials in 
the instant dentifrice. 
An alkali metal fluorine-providing compound may be employed in the 
dentifrice of the invention. The alkali metal fluorine-providing compound 
includes sodium fluoride, potassium, fluoride, lithium fluoride, ammonium 
fluoride and complex fluorides, particularly alkali metal 
monofluorophosphates. These compounds exhibit satisfactory retentions of 
soluble fluoride in dentifrices of the instant invention. In particular, 
the level of retention of monofluorophosphate ion as fluoride with the 
alkali metal monofluorophosphates is quite high. The fluorine-containing 
compound is employed in amount which provides an effective nontoxic amount 
of fluorine-containing ion to the dentifrice typically about 0.01-1% by 
weight preferably about 0.1% fluorine. Thus, sodium fluoride is typically 
employed in amount of about 0.02-2% by weight, preferably about 0.2%, and 
sodium monofluorophosphate, Na.sub.2 PO.sub.3 F, in amount of about 
0.1-7.6% by weight, preferably about 0.76%. 
The alkali metal monofluorophosphates which may be employed include sodium 
monofluorophosphate, lithium monofluorophosphate, potassium 
monofluorophosphate and ammonium monofluorophosphate. The preferred salt 
is sodium monofluorophosphate, Na.sub.2 PO.sub.3 F, which as commercially 
available, may vary considerably in purity. It may be used in any suitable 
purity provided that any impurities do not substantially adversely affect 
the desired properties. In general, the purity is desirably at least about 
80%. For best results, it should be at least 85%, and preferably at least 
90% by weight of sodium monofluorophosphate with the balance being 
primarily impurities or by-products of manufacture such as sodium 
fluoride, water-soluble sodium phosphate salt, and the like. Expressed in 
another way, the sodium monofluorophosphate employed should have a total 
fluoride content of above 12%, preferably 12.7%; a content of not more 
than 1.5%, preferably not more than 1.2% of free sodium fluoride; and a 
sodium monofluorophosphate content of at least 12%, preferably at least 
12.1%, all calculated as fluorine. 
Other monofluorophosphate salts which may be used in the instant invention 
include monofluoropolyphosphates such as Na.sub.4 P.sub.3 O.sub.9 F, 
K.sub.4 P.sub.3 O.sub.9 F, (NH.sub.4).sub.4 P.sub.3 O.sub.9 F, Na.sub.3 
KP.sub.3 O.sub.9 F, (NH.sub.4).sub.3 NaP.sub.3 O.sub.9 F and Li.sub.4 
P.sub.3 O.sub.9 F. 
Antibacterial agents may also be employed in the oral preparations of the 
instant invention to provide a total content of such agents of up to about 
5% by weight. Typical antibacterial agents include: 
N.sup.1 -(4-chlorobenzyl)-N.sup.5 -(2,4-dichlorobenzyl) biguanide; 
p-chlorophenyl biguanide; 
4-chlorobenzyhydryl biguanide; 
4-chlorobenzyhydrylguanylurea; 
N-3-lauroxypropyl-N.sup.5 -p-chlorobenzylbiguanide; 
1-(lauryldimethylammonium)-8-(p-chlorobenzyldimethylammonium) octane 
dichloride; 
5,6-dichloro-2-guanidinobenzimidazole; 
N.sup.1 -p-chlorophenyl biguanidohexane; 
1,6-bis(2-ethylhexyl biguanido) hexane; 
5-amino-1,3- bis(2-ethylhexyl)-5-methylhexahydropyrimidine; 
and their non-toxic acid addition salts. 
Synthetic finely divided pyrogenic silica such as those sold under the 
trademarks Cab-O-Sil M-5, Syloid 244, Syloid 266 and Aerosil D-200 may 
also be employed in amounts of about 1-5% by weight to promote thickening 
or gelling of the dentifrice. 
The taste of the new composition may be modified by employing suitable 
flavoring or sweetening materials. Examples of suitable flavoring 
constituents include the flavoring oils, e.g. oils of spearmint, 
peppermint, wintergreen, sassafras, clove, sage, eucalyptus, marjoram, 
cinnamon, lemon and orange as well as methylsalicylate. Suitable 
sweetening agents include sucrose, lactose, maltose, sorbitol, sodium 
cyclamate, perillartine, and saccharine. Suitable flavor agent may 
comprise from about 0.01 to 5% or more of the compositions particularly 
when anionic surface active agent is present in the instant invention. 
Various other materials may be incorporated in the dentifrice formulations 
of this invention. Examples thereof are coloring or whitening agents or 
dyestuffs, preservatives, silicones, chlorophyll compounds, ammoniated 
materials such as urea, diammoniumphosphate and mixtures thereof, and 
other constituents. These adjuvants are incorporated in the instant 
compositions in amounts which do not substantially adversely effect the 
properties and characteristics are desired and selected and used in proper 
amount depending upon the particular type of preparation involved. 
The dentifrices should have a pH practicable for use. A moderately acid to 
alkaline pH is preferred.

The following specific examples are further illustrative of the nature of 
the present invention but is understood that the invention is not limited 
thereto. Dentifrice formulations are prepared in the usual manner and 
provide in situ flocculation of the siliceous polishing material, and all 
amounts and proportions are by weight except as otherwise indicated. 
EXAMPLE 1 
The following opacified gel dentifrices are prepared: 
______________________________________ 
TS 
A B 
______________________________________ 
Maltitol (75% solution) 
40.00 40.00 
Sodium aluminosilicate (silica 
containing about 1% combined 
alumina - Zeo 49B-Huber) 
18.00 18.00 
Pluronic F 108 Block Copolymer 
3.00 3.00 
Xanthan 1.70 1.70 
Polyox WSR 301 (Union Carbide) 
0.20 -- 
Titanium dioxide 0.40 0.40 
Flavor 0.50 0.50 
Sodium saccharin 0.20 0.20 
Deionized water Q.S. TO 100 
Q.S. TO 100 
______________________________________ 
Polyox WSR-301 is available from Union Carbide Corp. as granules of water 
soluble poly (ethylene oxide) resin having a molecular weight of about 
4,000,000 and a Brookfield viscosity of 1650-3850 cps. (25.degree. C., 
spindle 1, speed 2 rpm) when in water at 1% by weight. Likewise, similar 
foam and feel is attained when other water-soluble poly (ethylene oxide) 
resins available from Union Carbide Corp. as Polyox WSR-N-10, WSR-N-80, 
WSR-N-750, WSR-N-3000, WSR-205 and WSR 1105 replace Polyox WSR-301, in 
different concentrations. 
Both dentifrices provide stable full-bodied foam with good mouth feel; the 
mouth feel of dentifrice A being particularly satisfactory. 
When compared for ability to remove dental stain and in dentin abrasion, 
dentifrice A containing the Polyox material removes more stain with less 
dentin abrasion than dentifrice B, without Polyox material. In dentifrice 
A, flocculated particles of sodium aluminosilicate form in situ. 
The results are as follows: 
______________________________________ 
PERCENT RADIOACTIVE 
DENTIFRICE 
STAIN REMOVAL DENTIN ABRASION 
______________________________________ 
A 35 14 
B 22 39 
______________________________________ 
In a stain removal test, sections of human dental enamel are etched with 
0.1 N HCl for 2 minutes, rinsed with water, then wet with a dilute 
solution of stannous fluoride, wiped dry, and finally exposed to a stream 
of hydrogen sulfide gas which results in the deposition of a brown deposit 
of stannous sulfide. The amount of stain on the surface is measured with a 
Gardner Automatic Color Difference meter. The surface is then brushed with 
a mechanical brushing machine for 500 reciprocal strokes with a slurry of 
a dentifrice and the residual stain measured with the meter. Finally, the 
stain which remains is completely removed with dental pumice and the 
reflectance of this surface is read. The ability of a dentifrice to remove 
the stain is expressed by the following equation. 
##EQU1## 
where .sup.Rd initial, .sup.Rd 500 strokes, and .sup.Rd pumiced are 
respectively the reflectance values measured on the initially stained 
surfaces, after brushing for 500 reciprocal strokes and after removing the 
residual stain by pumicing. 
The RDA values are obtained by a procedure based on a radioactive technique 
described in the literature; Stookey, C. K. and Muhler, J. C., J. Dental 
Research 47 524-538 (1968); Hefferren, J. J., J. Dental Research 55 
563-573 (1976). 
EXAMPLE 2 
The following dentifrices are prepared: 
______________________________________ 
TS 
A B 
______________________________________ 
Maltitol (75% solution) 
40.00 40.00 
Sodium aluminosilicate (silica con- 
taining combined about 1% combined 
alumina - Zeo 49B - Huber) 
18.00 18.00 
Calcined alumina 5.00 5.00 
Pluronic F-108 3.00 3.00 
Xanthan 1.70 1.70 
Polyox WSR 301 (Union Carbide) 
0.20 -- 
Titanium dioxide 0.40 0.40 
Flavor 0.50 0.50 
Sodium saccharin 0.10 0.10 
Deionized water Q.S. to 100 
Q.S. to 100 
______________________________________ 
Both dentifrices provide stable full-bodied foam with good mouth feel; the 
mouth feel of dentifrice A being particularly satisfactory. 
The following stain removal and radioactive dentin abrasion results were 
obtained with dentifrices A and B, evidencing superiority for dentifrice 
A, containing the Polyox material with regard to higher stain removal with 
similar dentin abrasion. 
______________________________________ 
DENTIFRICE PERCENT STAIN REMOVAL 
RDA 
______________________________________ 
A 65 44 
B 47 41 
______________________________________ 
EXAMPLES 3-4 
The following opacified gel dentifrices are prepared: 
______________________________________ 
EXAMPLES 
3 4 
______________________________________ 
Glycerine 10.0 10.0 
Maltitol 15.0 15.0 
Sodium aluminosilicate (silica 
combined with about 1% 
combined alumina) Zeo 49B 
(Huber) 18.0 18.0 
Pluronic 108 block copolymer 
-- 3.0 
Sodium lauryl sulfate 
1.0 -- 
Xanthan 2.0 2.0 
Polyox WSR 301 0.2 0.2 
Sodium monofluorophosphate 
0.76 0.76 
Titanium dioxide 0.4 0.4 
Low menthol flavor -- 0.5 
Peppermint oil flavor 
0.5 -- 
Sodium saccharin 0.2 -- 
Color solution (1%) 
0.05 0.05 
Water Q.S. to 100 Q.S. to 100 
______________________________________ 
The dentifrice of Example 3 with sodium lauryl sulfate has desirable foam 
character. The dentifrice of Example 4 also has very good stable 
full-bodied foam character even though no anionic surface active agent is 
employed. The foam remains throughout the oral cavity, with desirable 
mouth feel, when the dentifrice is brushed onto the teeth. Moreover, it 
has no bitter note even though low menthol flavor is present and no 
sweetener is added. The dentifrices have fine smooth texture and 
appearance, effectively remove stain and have acceptable dentin abrasion 
character. They contain flocculated particles of sodium aluminosilicate. 
Although this invention has been described with regard to illustrative 
examples, it will be apparent to one skilled in the art that various 
modifications may be made thereto which fall within its scope.