Skin treatment compositions comprising unoxidized nerve tissue

Method for retexturizing and smoothening the skin comprising topically applying to the skin a composition comprising from about 1.5 to about 2.5 parts by weight of a powdery, cosmetically acceptable inorganic material, such as calcium carbonate, and about 1 part by weight of nerve tissue such as the spinal cord.

BACKGROUND OF THE INVENTION 
Although adequate washing with soap and water will remove surface grime, 
facial makeup and oils from the face, it is well recognized that for this 
purpose the use of specially formulated cleansing creams and lotions has 
certain advantages. For example, the special chemical nature of facial 
makeup leads to the use of specific formulations for dissolving or lifting 
the oily binding materials in the makeup which hold the pigments therein, 
as well as the grime settling thereon, from the skin. 
Natural skin oil, sebum, is a product of normal metabolism and is excreted 
from sebaceous glands in the skin. These oils tend to solidify over the 
sebaceous orifice to form hardened plaques which are difficult to remove 
by washing with only soap and water. Even scrubbing with soap and water 
fails to remove these plaques. Furthermore, although the plaques are 
formed from fatty materials they are surprisingly resistant to dissolution 
in the usual solvents for fats such as acetone, chloroform, glycerine, 
kerosene, hexane, dioxane, trichloroethylene, ethanol, and the like, which 
readily remove surface oils on the skin but are inefficient in dissolving 
the solid plaques. 
The formation of these plaques gives the skin a rough and aged appearance, 
and the appearance is further marred by the constant drying of the 
outermost epidermal cells. These dead dry cells remain on the skin adding 
to the rough appearance. 
Preparations such as skin lotions, creams and the like are available for 
cleaning the skin and removing plaques. Some of these preparations contain 
abrasive materials such as borax particles which aid in the removal of 
plaques as well as the rough dead skin. However, although these 
compositions may be effective in removing the plaques and cell debris, 
they do not leave the skin with a smooth appearance and feel. 
DESCRIPTION OF THE INVENTION 
It is an object of this invention to provide a composition and a method by 
which undesirable material adhering to the skin may be removed. 
It is another object of this invention to provide a composition and a 
method by which undesirable material adhering to the skin may be removed 
and the skin left with a smooth appearance and feel. 
It is a further object of this invention to provide compositions for 
removing undesirable matter from the skin which can be conveniently 
applied to the skin. 
Other objects will appear from the discussion which follows. 
In accordance with this invention there are provided compositions comprised 
of a cosmetically acceptable inorganic material and nerve tissue. 
Cosmetically acceptable materials, such as the cosmetically acceptable 
inorganic materials used in the practice of this invention, are 
pharmaceutically inert with respect to the skin. 
Cosmetically acceptable inorganic materials suitable for the practice of 
this invention include calcium salts such as the acetate, carbonate, 
formate, gluconate, lactate, oxalate, phosphate, and stannate, calcium 
carbonate, magnesium carbonate, zinc carbonate, magnesium aluminum 
silicate, silica, zinc aluminum silicate, talc and the like. These 
materials, or mixtures thereof, are used in finely powdered form. Calcium 
carbonate (USP grade) is preferred. 
The nerve tissue may be obtained from nerves per se, spinal cords, and 
brains. Spinal cords are preferred. 
In preparing the compositions of this invention from about 1.5 to about 2.5 
parts by weight of the powdery cosmetically acceptable inorganic material 
was mixed with about 1 part by weight of unoxidized nerve tissue by 
grinding at a temperature from about 20.degree. to about 70.degree. C. 
until a doughy mix was obtained. The doughy mix may be formed into tablets 
having a disc-like shape and a thickness from about 1/8 to about 3/8" and 
a diameter from about 1/2 to about 1", or dried at a temperature from 
about 20.degree. to about 70.degree. C. for about 3 to 24 hours. A solid, 
whitish material was obtained on drying. This material may, when desired, 
be ground to a powder which can be used directly or put into tablets, 
creams or lotions.

The invention will become clearer from the examples which follow. These 
examples are given only by way of illustration and are not to be 
considered as limiting. 
EXAMPLE 1 
To 30 g calcium carbonate powder (USP) was added 15 g of cattle spinal cord 
from which the lamina had been removed and which had been washed well with 
water to remove any adhering tissue and blood stains. This mixture of 
calcium carbonate and the spinal cord was ground at about 70.degree. C. 
until a substantially uniform doughy mixture was obtained. The ground 
mixture was air dried at ambient temperatures (about 20.degree. to 
25.degree. C.) for about 24 hours to form a solid white material. 
EXAMPLE 2 
The procedure of example 1 was repeated, except that the drying operation 
was carried out by heating in a vacuum oven at about 45.degree. C. for 
about 8 hours. 
EXAMPLE 3 
The procedure of example 1 was repeated, except that the grinding operation 
was carried out at about 50.degree. C. 
EXAMPLE 4 
The procedure of example 1 was repeated through the grinding stage. The 
doughy mixture was then shaped into tablets of disc-like shape having a 
thickness of about 1/4" and a diameter of about 3/4". The tablets were 
then dried by heating at about 70.degree. C. for about 3 hours. 
EXAMPLE 5 
The procedure of example 4 was repeated, except that the tablets had a 
thickness of about 1/8" and a diameter of about 3/4". 
EXAMPLE 6 
The solid white material of example 1 was ground to a powder and 
incorporated in a lotion of the following composition using standard 
techniques for the preparation of lotions: 
______________________________________ 
Material Parts by Weight 
______________________________________ 
Triethanolaminelauryl sulfate 
5 
Mineral oil 65/75 20 
Beeswax 2 
Calcium carbonate-spinal cord mixture 
20 
Preservative 0.1 
Water q.s. 100 
______________________________________ 
A suitable preservative for use in this composition and in the composition 
of example 7 below is ethyl hydroxy-benzoate. 
EXAMPLE 7 
A cream of the following composition containing the powdered product of 
example 1 was prepared using standard techniques. The composition was as 
follows: 
______________________________________ 
Material Parts by Weight 
______________________________________ 
Beeswax 10 
Mineral oil 40 
Paraffin 10 
Ozokerite 5 
Calcium carbonate-spinal cord mixture 
10 
Preservative 0.1 
Water q.s. 100 
______________________________________ 
The tablets, powder, lotion and cream remained stable, showing no signs of 
disintegration or spoilage, after standing at ambient temperature (about 
20.degree. to 25.degree. C.) for 6 months. 
When using the compositions of this invention, the skin is first rinsed 
with warm water and the cmposition in the form of a powder, tablet, cream 
or lotion is rubbed into the wet skin and the skin is then gently 
massaged. The material is then rinsed off with warm water and the skin 
dried. The product may be applied from one to seven times weekly. It has 
been found that after the treatment with the composition of the present 
invention the skin has a clean smooth appearance and feel.