PharMolix/UniProtQA huggingface dataset:
Protein: YEAH_ECO5E
Sequence: MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGVPANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAELRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNPAQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHLQSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKD
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: PRDM2_RAT
Sequence: MHQNTESVAATETLAEVPEHVLRGLPEEVRLFPSAVDKTRIGVWATKPILKGKKFGPFVGDKKKRSQVRNNVYMWEVYYPNLGWMCIDATDPEKGNWLRYVNWACSGEEQNLFPLEINRAIYYKTLKPIAPGEELLVWYNGEDNPEIAAAIEEERASARSKRSSPKSRRGKKKSHENKNKGIRTHPTQLKASELDSTFANMRGSAEGPKEEDERPLASAPEQPAPLPEVGNQDAVPQVAIPLPACEPQPEVDGKQEVTDCEVNDVEEEELEEEEELEEEEEEELGEDGVEEADMPNESSAKEPEIRCEEKPEDLLEEPQSMSNEAREDSPDVTPPPHTPRAREEANGDVLETFMFPCQHCERKFATKQGLERHMHIHISTINHAFKCKYCGKRFGTQINRRRHERRHETGLKRRPSMTLQSSEDPDDGKGENVTSKDESSPPQLGQDCLILNSEKTSQEVLNSSFVEENGEVKELHPCKYCKKVFGTHTNMRRHQRRVHERHLIPKGVRRKGGLLEEPQPPAEQAPPSQNVYVPSTEPEEEGETDDVYIMDISSNISENLNYYIDGKIQTNSSTSNCDVIEMESNSAHLYGIDCLLTPVTVEITQNIKSTQVSVTDDLLKDSPSSTNCESKKRRTASPPVLPKIKTETESDSTAPSCSLSLPLSISTAEVVSFHKEKGVYLSSKLKQLLQTQDKLTLPAGFSAAEIPKLGPVCASAPASMLPVTSSRFKRRTSSPPSSPQHSPALRDFGKPNDGKAAWTDTVLTSKKPKLESRSDSPAWSLSGRDERETGSPPCFDEYKISKEWAASSTFSSVCNQQPLDLSSGVKQKSEGTGKTPVPWESVLDLSVHKKPCDSEGKEFKENHLAQPAAKKKKPTTCMLQKVLLNEYNGVSLPTETTPEVTRSPSPCKSPDTQPDPELGPDSSCSVPTAESPPEVVGPSSPPLQTASLSSGQLPPLLTPTEPSSPPPCPPVLTVATPPPPLLPTVPLSHPSSDASPQQCPSPFSNTTAQSPLPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSFPSSSCSSTSPSPPPLSAVSSVVSSGDNLEASLPAVTFKQEESESEGLKPKEEAPPAGGQSVVQETFSKNFICNVCESPFLSIKDLTKHLSVHAEEWPFKCEFCVQLFKVKTDLSEHRFLLHGVGNIFVCSVCKKEFAFLCNLQQHQRDLHPDEVCTHHEFESGTLRPQNFTDPSKANVEHMPSLPEEPLETSREEELNDSSEELYTTIKIMASGIKTKDPDVRLGLNQHYPSFKPPPFQYHHRNPMGIGVTATNFTTHNIPQTFTTAIRCTKCGKGVDNMPELHKHILACASASDKKRYTPKKNPVPLKQTVQPKNGVVVLDNSGKNAFRRMGQPKRLSFNVELGKMSPNKLKLSALKKKNQLVQKAILQKNRAAKQKADLRDTSEASSHICPYCDREFTYIGSLNKHAAFSCPKKPLSPSKRKVSHSSKKGGHASSSSSDRNSSCHPRRRTADTEIKMQSTQAPLGKTRARSTGPAQASLPSSSFRSRQNVKFAASVKSKKASSSSLRNSSPIRMAKITHVEGKKPKAVAKSHSAQLSSKSSRGLHVRVQKSKAVIQSKTALASKRRTDRFIVKSRERSGGPITRSLQLAAAADLSESRREDSSARHELKDFSYSLRLASRCGSSTASYITRQCRKVKAAAATPFQGPFLKE
What is the function of this protein?
S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3.  May function as a DNA-binding transcription factor.  Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene (By similarity).
What are the official names of this protein?
PR domain zinc finger protein 2, PR domain-containing protein 2, Retinoblastoma protein-interacting zinc finger protein, Zinc finger protein RIZ.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS6_STRAW
Sequence: MRHYEVMVILDPDLEERAVSPLIENFLSVVREGNGKVEKVDTWGRRRLSYEIKKKPEGIYSVIDLQAEPAVVKELDRQMNLNESVLRTKVLRPETH
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: Y2512_CERS1
Sequence: MTDLYIDADACPVKAEAERVAVRHGVRMFLVSNGGIRPPAHPLVESIFVPEGPDVADMWIADRARTGDVVVTSDIPLAAKVVAAGALVVKPNGETLTTANIGNALATRDLMADLRSADPFRQGGGRTFSKADRSRFLDALERAMRKAQEAGRSASGGSEAGS
What are the official names of this protein?
UPF0178 protein Rsph17029_2512.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: Y748_THEPD
Sequence: MGRLSAEEGALLVRLARRAVEEYLENARVIEPPRDTPPSLREKSGVFVTIEKILVDPLARRARRELRGCIGYPEPVLPLAEATIHAAIAAATEDPRFPPMTPRELDTVVFEVSVLTKPEPVDYRSPEELPDKIKVGRDGLIVEYGAARGLLLPQVAVDEGWDPEEFLSYACLKAGLRDDAWRHGGLKVYRFQAQIFVETTPKGDVVERFLEVV
What are the official names of this protein?
Protein Tpen_0748.
Protein: PEPVL_STAA8
Sequence: MWKEKVQQYEDQIINDLKGLLAIESVRDDAKASEDAPVGPGPRKALDYMYEIAHRDGFTTHDVDHIAGRIEAGKGNDVLGILCHVDVVPAGDGWDSNPFEPVVTEDAIIARGTLDDKGPTIAAYYAIKILEDMNVDWKKRIHMIIGTDEESDWKCTDRYFKTEEMPTLGFAPDAEFPCIHGEKGITTFDLVQNKLTEDQDEPDYELITFKSGERYNMVPDHAEARVLVKENMTDVIQDFEYFLEQNHLQGDSTVDSGILVLTVEGKAVHGMDPSIGVNAGLYLLKFLASLNLDNNAQAFVAFSNRYLFNSDFGEKMGMKFHTDVMGDVTTNIGVITYDNENAGLFGINLRYPEGFEFEKAMDRFANEIQQYGFEVKLGKVQPPHYVDKNDPFVQKLVTAYRNQTNDMTEPYTIGGGTYARNLDKGVAFGAMFSDSEDLMHQKNEYITKKQLFNATSIYLEAIYSLCVEE
What are the official names of this protein?
Putative dipeptidase SAOUHSC_01868.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
Protein: RL14_CLOTE
Sequence: MIQQQTTLKVADNSGARGIMCIKVLGGSNRRYANIGDIIVASVKSATPGGVVKKGEVVKAVVVRSKKGVRRADGSYIKFDENAAVIIKDDKQPKGTRIFGPVARELRDKEFNKILSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RL20_BURCH
Sequence: MPRVKRGVTARARHKKIINLAKGYRGRRNNVYRIAKQAVMRAGQYAYRDRRNKKRVFRALWITRINAAVRQHDMTYSVFINGLKKASIELDRKVLADMAVFDKAAFAAIVKQVKAAVAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: XYL2_PICST
Sequence: MTANPSLVLNKIDDISFETYDAPEISEPTDVLVQVKKTGICGSDIHFYAHGRIGNFVLTKPMVLGHESAGTVVQVGKGVTSLKVGDNVAIEPGIPSRFSDEYKSGHYNLCPHMAFAATPNSKEGEPNPPGTLCKYFKSPEDFLVKLPDHVSLELGALVEPLSVGVHASKLGSVAFGDYVAVFGAGPVGLLAAAVAKTFGAKGVIVVDIFDNKLKMAKDIGAATHTFNSKTGGSEELIKAFGGNVPNVVLECTGAEPCIKLGVDAIAPGGRFVQVGNAAGPVSFPITVFAMKELTLFGSFRYGFNDYKTAVGIFDTNYQNGRENAPIDFEQLITHRYKFKDAIEAYDLVRAGKGAVKCLIDGPE
What are the official names of this protein?
D-xylulose reductase, Xylitol dehydrogenase, XDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: GABP1_BOVIN
Sequence: MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVTIHAATPQFIIGPGGVVNLTDETGVSAVQFGNSSTSVLATLAALAEASAPLSNSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLHSIPTSGIGQPIIVTMPDGQQVLTVPATDIAEETVISEEPPAKRQCIEIIENRVESAEIEEREALQKQLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV
What is the function of this protein?
Transcription factor capable of interacting with purine rich repeats (GA repeats).  Acts as a a master regulator of nuclear-encoded mitochondrial genes.
What are the official names of this protein?
GA-binding protein subunit beta-1, GABP subunit beta-1, GABPB-1, GABP subunit beta-2, GABPB-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: NRFA_BACFR
Sequence: MEKKLKSWQGWLLFCGAMAVVFVLGLVVSSLMERRAETVSVFNNKRVEITGIEARNEVFGENYPRQYETWKETAKTDFKSEFNGNEAVDVLEQRPEMVVLWAGYAFSKDYSTPRGHMHAIEDITHSLRTGAPMDDKSGPQPSTCWTCKSPDVPRMMEAIGVDSFYNNKWGAFGSEIVNPIGCADCHEPTNMKLHISRPALREAFARQGKDIDKATPQEMRSLVCAQCHVEYYFKGDGKYLTFPWDKGFSVEDMEAYYDEADFADYTHALSKARILKAQHPDYEISQMGIHAQRGVSCADCHMPYKSEGGMKFSDHHIQSPLAMIDRTCQVCHRESEETLRNNVYDRQRKANEIRGRLEQELAKAHIEAEFAWDKGATDVQMAEALKLIRQAQWRWDFGVASHGGAFHAPQEIQRILGHGLDKALQARLAISKVLAQHGYTADVPMPDISTKEKAQEYIGLDMEKERKAKGKFLKTIVPEWLEKARANGRLAKL
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TIG_FRACC
Sequence: MKATKETLSPTRVKLTVEVPFDELKPSLEATYRKLARQVRVSGFRPGKVPPRILDQRLGRGVILDEAVQEALPQLYSEAVQAEEVDVLSRPEVDITEFADGGQLVFTAEVDVRPEVTLPEFSELEITVDAVEVTDEQVEEQLGALRDRFAVLTPVERAVQAGDYVSLDLSAEADGTPIDGAEATGLSYEVGSGNLVEGLDDAIIGATDGETRTFTTELLSGEQAGQPAQVTATVRGVKEKELPALDDDFATTASEFDTLDELRADIRTRLEQSRRTEQVGQAREKLLESLLERVEVPVPGSLLAGEIEAREHRLSRELEYIGTDRPSYLETLGQTEEEFDAEVRESAGKAIRSQFILDAVIDAESIGIDQGELMEQLILRAQRSGVQPDVYAQQLAQGEGLTALMADVLRTKALFLLLENAKVVDGAGTPVELALPARSQPDTDADADHDRDVTVAAEAVAPGDGDATVEPVEPVEAETDGNG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PSAI_SPIOL
Sequence: MNFPSIFVPLVGLVFPAIAMASLFLYVQKNKIV
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ECM14_YEAST
Sequence: MLHMNSLWGCFLFVLLAVTGAVQGLQEDYSEYAVYRFTSDNYSTLVRDVIAPLTDDYDVWTRSNNFIDIKLPKEIGEQINDGQVIIDNMNELIQNTLPTSQMMAREQAVFENDYDFFFNEYRDLDTIYMWLDLLERSFPSLVAVEHLGRTFEGRELKALHISGNKPESNPEKKTIVITGGIHAREWISVSTVCWALYQLLNRYGSSKKETKYLDDLDFLVIPVFNPDGYAYTWSHDRLWRKNRQRTHVPQCLGIDIDHSFGFQWEKAHTHACSEEYSGETPFEAWEASAWYKYINETKGDYKIYGYIDMHSYSQEILYPYAYSCDALPRDLENLLELSYGLSKAIRSKSGRNYDVISACKDRGSDIFPGLGAGSALDFMYHHRAHWAFQLKLRDTGNHGFLLPPENIKPVGKETYAALKYFCDFLLDPEI
What is the function of this protein?
Inactive carboxypeptidase that may play a role in cell wall organization and biogenesis.
What are the official names of this protein?
Inactive metallocarboxypeptidase ECM14, Extracellular mutant protein 14.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Vacuole. Secreted.
Protein: SYV_STAAW
Sequence: MEMKPKYDPREVEAGRYEEWVKNGYFKPSEDKSKETYTIVIPPPNVTGKLHLGHAWDTTLQDIITRMKRMQGYDTLYLPGMDHAGIATQAKVEAKLNEQGITRYDLGREKFLEQAWDWKEEYASFIRAQWAKLGLGLDYSRERFTLDEGLSKAVKKVFVDLYNKGIIYRGERIINWDPKARTALSDIEVIHEDVQGAFYHFKYPYADGEGFIEIATTRPETMLGDTAIVVNPNDERYKDVIGKTVILPIVGRELPILADEYVDIDFGSGAMKVTPAHDPNDFEIGQRHQLENIIVMDENGKMNDKAGKYEGMDRFDCRKQLVKDLKEQDLVIKIEDHVHSVGHSERSGAVVEPYLSTQWFVRMEDLAKRSLDNQKTDDRIDFYPQRFEHTFNQWMENIRDWTISRQLWWGHQIPAWYHKETGEIYVGEEAPTDIENWQQDEDVLDTWFSSALWPFSTLGWPDLESEDFKRYYPTNALVTGYDIIFFWVARMIFQGLEFTDRRPFNDVLLHGLVRAEDGRKMSKSLGNGVDPMDVIDEYGADSLRYFLATGSSPGHDLRYSTEKVESVWNFINKIWNGARFSLMNIGEDFKVEDIDLSGNLSLADKWILTRLNETIATVTDLSDKYEFGEVGRALYNFIWDDFCDWYIEMSKIPMNSNDEEQKQVTRSVLSYTLDNIMRMLHPFMPFVTEKIWQSLPHEGDTIVKASWPEVRESLIFEESKQTMQQLVEIIKSVRQSRVEVNTPLSKEIPILIQAKDKEIETTLSQNKDYLIKFCNPSTLNISTDVEIPEKAMTSVVIAGKVVLPLEGLIDMDKEISRLEKELAKLQSELDRVDKKLSNENFVSKAPEKVINEEKRKKQDYQEKYDGVKARIEQLKA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_STAAT
Sequence: MLNYNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVIDGVSERGGHPVYRKPMKQWVLKITEYADQLLADLDDLDWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKSGVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPIIEVIEGGNVEEAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQRYWGEPIPVIHWEDGTMTTVPEEELPLLLPETDEIKPSGTGESPLANIDSFVNVVDEKTGMKGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLAIVPTKEPFQKLFNQGMILGEGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKLGHEESITYQPWPTYDEALLVDDEVEIVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRDB_BACMK
Sequence: MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLSVLGSIMIKATTEQPRYGNPTPRVAETPGGMLNAIGLQNPGLEKVMNSELPFLEQFDLPIIANVAGSQAEDYVAVAKAISKAPNVHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEVPVYVKLSPNVANIVEIAKAIENAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVALRMVHEVSQAVNIPIIGMGGIETAEDVIEFFYAGASAVAVGTANFIDPFVCPTIIEELPALLDELGFDHISECQGRSWKQTCHSR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCL3_KLULA
Sequence: MTEQRTVTNNATHYFYPTVLLFSILLTGGVLTATSFYNKHLRQYKSAKDIPEAIFKKQWLYGKVTSVGDGDNFHFFHTPSGIFGGWGWLRSIPELQTVAFDASVEVPQSVRWWNKLFSAKVANYKSHFMSLHVPYKGRRNLPTISVRLCGVDAPERSHFGKTAQPFSDEALNWLRYKILGQYVWVKPLAVDQYGRCVARVELWSWLKGWQNISIEMLKEGVGVVYEGKVGAEFDNQEDIYLYEELNSKKAKRGLWSQRKFETPGAYKKRT
What are the official names of this protein?
Probable endonuclease LCL3.
What is the protein family that this protein belongs to?
Belongs to the LCL3 family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Single- pass membrane protein.
Protein: DNLJ_MYCSJ
Sequence: MSAKSTPDAGPQEQATEAEAELRHRWQALADEVRDHQFRYYVRDAPVISDADFDKLFQQLEALEAEHPELRAPDSPTQLVGGAGFATDFTPAEHLERMLSLDDVFNVDELTAWSSRVRAEVGDDAAYLCELKVDGLALALVYRDGRLERAATRGDGRVGEDVTLNARTLDDVPERLTPSDEFPHPAVLEVRGEVFFRVADFEALNAGLVAEGKPPFANPRNSAAGSLRQKNPAVTARRPLRMVCHGIGYTEGFSPTSLHEAYGALRAWGLPVSDHTTRVQGMDAVRERIAYWGEHRHDIEHEIDGVVVKLDQIALQRRLGATSRAPRWAVAYKYPPEEAQTKLLDIRVNVGRTGRVTPFAYMEPVKVAGSTVGLATLHNASEVKRKGVLIGDTVVIRKAGDVIPEVLGPVVDLRDGTEREFVMPTHCPECGTELAPAKEGDADIRCPNSRTCPAQLRERVFHVAGRGAFDIEGLGYEAAIALLQAGVITDEGDLFTLTEDDLLRTELFTTKGGAVSANGRRLLANLGKAKAQPLWRVLVALSIRHVGPTAARALATEFGSLDAIIEASEDQLAAVEGVGPTIAAAVKEWFTVDWHCAIVEKWRAAGVRMADERDASIARTLEGLSIVVTGSLAGFSRDEAKEAIIARGGKAAGSVSKKTAYVVAGDSPGSKYDKAIDLGVPVLDEDGFRNLLENGPQAPEG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: GLMM_BACAC
Sequence: MGKYFGTDGVRGVANKELTPELAFKIGRFGGYVLTKDTDRPKVIIGRDTRISGHMLEGALVAGLLSTGAEVMRLGVISTPGVAYLTKALDAQAGVMISASHNPVQDNGIKFFGSDGFKLTDEQEAEIEALLDKEVDELPRPTGTNLGQVSDYFEGGQKYLQYIKQTVEEDFSGLHIALDCAHGATSSLAPYLFADLEADISTMGTSPNGMNINDGVGSTHPEVLAELVKEKGADIGLAFDGDGDRLIAVDEKGNIVDGDQIMFICAKYMKETGQLKHNTVVSTVMSNLGFYKALEANGITSDKTAVGDRYVMEEMKRGGYNLGGEQSGHIILLDYITTGDGMLSALQLVNIMKMTKKPLSELAGEMTKFPQLLVNVRVTDKKLALENEKIKEIIRVVEEEMNGDGRILVRPSGTEPLIRVMAEAPTQEVCDAYVHRIVEVVKAEVGAE
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RL31B_YERPN
Sequence: MKPNIHPPYRTVVFHDTSADAYFTVGSTIATERTIERDGQTYPYVTLDISSASHPYYTGKQKEFAKEGSTARFHQRFGSFLTKKTN
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: RS15_PSEE4
Sequence: MALSVEEKAQIVAEYQQAAGDTGSPEVQVALLTANINKLQGHFKANEKDHHSRRGLIRMVNQRRKLLDYLKGKDTTRYSALIGRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RAC1_CAEEL
Sequence: MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLGLWDTAGQEDYDRLRPLSYPQTDVFLVCFALNNPASFENVRAKWYPEVSHHCPNTPIILVGTKADLREDRDTVERLRERRLQPVSQTQGYVMAKEIKAVKYLECSALTQRGLKQVFDEAIRAVLTPPQRAKKSKCTVL
What is the function of this protein?
Required in engulfing to control the phagocytosis of apoptotic cell corpses (PubMed:10707082, PubMed:20126385).  Required in embryonic development for the correct positioning and orientation of the mitotic spindles and division planes in blastomere cells (PubMed:20126385).  Involved in hypodermal cell fusion, together with pak-1 and cdc-42, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization (PubMed:8824291).  ced-2 and ced-5 function to activate ced-10 in a GTPase signaling pathway that controls the polarized extension of cell surfaces (PubMed:10707082).  Plays a redundant role with mig-2 in dorsal axonal guidance in ventral cord commissural motoneurons and in P neuroblast migration.  May regulate these 2 processes by activating pak-1 and/or max-2 (PubMed:17050621).  Plays a role, probably via mig-10, in orientating axonal growth of HSN and AVM neurons in response to guidance cues such as slt-1.  Regulates mig-10 asymmetric distribution in HSN neurons (PubMed:18499456).  During the dorso-ventral axonal guidance and outgrowth of VD neurons, required together with mig-2 to inhibit growth cone filopodial protrusion mediated by netrin guidance cue unc-6 and its receptors unc-5 and unc-40 (PubMed:25371370, PubMed:30045855).  Specifically, regulates growth cone filopodial protrusion polarity, and thus migration, by promoting F-actin polarization and, together with mig-2, by restricting plus-end microtubule accumulation in the growth cone (PubMed:30045855).  Plays a role in protecting dopaminergic neurons from oxidative stress-induced degeneration (PubMed:29346382).  During gonad morphogenesis, plays a role in distal tip cell (DTC)-mediated guidance of gonad elongation, probably by activating max-2 (PubMed:19797046, PubMed:19023419).  Furthermore, plays a role in distal tip cell polarity and migration by negatively regulating the unc-6/Netrin receptor unc-5 (PubMed:26292279).  May be involved in signal transduction during cell migration (PubMed:10707082).  May be involved in the positioning of ray 1, the most anterior ray sensilium, in the male tail (PubMed:24004945).
What are the official names of this protein?
Ras-related protein ced-10, CErac1, Cell death protein 10, Cell-corpse engulfment protein ced-10, Ras-related protein rac-1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Note=Co-localizes with pak-1 and cdc-42 at hypodermal cell boundaries during embryo elongation.
Protein: MPH1_YEAS7
Sequence: MASADDYFSDFEDDELDKLYEKAINKSVKETITRRAVPVQKDLHDNVLPGQKTVYEEIQRDVSFGPTHHELDYDALSFYVYPTNYEVRDYQYTIVHKSLFQNTLCAIPTGMGKTFIASTVMLNYFRWTKKAKIIFTAPTRPLVAQQIKACLGITGIPSDQTAILLDKSRKNREEIWANKRVFFATPQVVENDLKRGVLDPKDIVCLVIDEAHRATGSYAYTNVVKFIDRFNSSYRLLALTATPASDLEGVQEVVNNLDISKIEIRTEESMDIVKYMKKRKKEKIEVPLLLEIEDIIEQLGIAVKPVLQQAIELGIYEECDPSQINAFKAMQQSQKIIANPTIPEGIKWRNFFILQLLNNVGQMLKRLKIYGIRTFFNYFQNKCTEFTTKYNLKKSTNKIAAEFYYHPILKNIKNQCENYLSDPKFVGHGKLQCVRDELMEFFQKRGSDSRVIIFTELRESALEIVKFIDSVANDQIRPHIFIGQARAKEGFDEVKYTRKHAPKGRKKVERLHRQEQEKFLEAERTKRAANDKLERSARRTGSSEEAQISGMNQKMQKEVIHNFKKGEYNVLVCTSIGEEGLDIGEVDLIICYDTTSSPIKNIQRMGRTGRKRDGKIVLLFSSNESYKFERAMEDYSTLQALISKQCIDYKKSDRIIPEDIIPECHETLITINDENEIINEMEDVDEVIRYATQCMMGKKVKPKKAITKKKRVQENKKPKKFFMPDNVETSIVSASTLINKFLVNESGGKQLVTSNENPSKKRKIFKALDNLENDSTEEASSSLETEDEEFSDDNNVFIAEGQNGCQKDLETAIIRTGESLTTLKPLHNFERPNMALFVNDCGLPTKIEKNVKDIRGNQHNLEKEKNCTVDKNNMVLSLDDWNFFRDRYIPEGVSFDVEPNFVQYTKGVKVPHCHKVSKIITLFNDESNDNKKRTIDMNYTKCLARGMLRDEKKFVKVNDKSQVDNNSVNHDSSQSFTLSNAELDDILGSDSDF
What is the function of this protein?
ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance.  Capable of unwinding D-loops.  Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair.  Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
What are the official names of this protein?
ATP-dependent DNA helicase MPH1, FANCM-like protein 1, Mutator phenotype protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVB_CELJU
Sequence: MIETDRLIAPTAKEREDQLDRAVRPKVLADYVGQPAVREQMEIFICAAKKRREALDHTLVFGPPGLGKTTLANIIANEMGVSLKSTSGPVLEKAGDLAAMLTNLEAGDVLFIDEIHRLSPVVEEILYPAMEDFQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGLLTSPLRDRFGIVQRLEFYNVKDLTHIVARSAALLGVSMEELGAAEIAKRSRGTPRIANRLLRRVRDFAEVKGDGRITSELADKALNMLNVDERGFDHMDRRLLLAMINNFDGGPVGVESLAAAISEDRGTIEDVIEPYLIQQGFMARTPRGRVLTTNAYLHFGLSMPKRLQESQGGEGIA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.