PharMolix/UniProtQA huggingface dataset:
Protein: RS16_BRUAB
Sequence: MALKIRLARAGSKKRPYYHVVVADVRAPRDGRFIETVGSWNPVLPKDAERVKLDAERIQHWIAQGAQPTDRVLRFLDQAGIAKRPSRNNPTKGEPGKKAQERLALAKQAEEEASAKAAEAAAAAAAPAEEAASE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: G6PI2_GEOSE
Sequence: MAISFDYSNALPFMQENELDYLSEFVKAAHHMLHERKGPGSDFLGWVDWPIRYDKNEFSRIKQAAERIRNHSDALVVIGIGGSYLGARAAIEALSHTFHNQMNDTTQIYFAGQNISSTYISHLLDVLEGKDLSINVISKSGTTTEPAIAFRIFRDYMEKKYGKEEARKRIYVTTDRTKGALKKLADQEGYETFVIPDNIGGRYSVLTAVGLLPIAVAGLNIDRMMEGAASAYHKYNNPDLLTNESYQYAAVRNILYRKGKAIELLVNYEPSLHYVSEWWKQLFGESEGKDQKGLFPASVDFTTDLHSMGQYVQEGRRNLIETVLHVKKPQIELTIQEDPENIDGLNFLAGKTLDEVNKKAFQGTLLAHVDGGVPNLIVELDEMNEYTFGEMVYFFEKACGISGHLLGVNPFDQPGVEAYKKNMFALLGKPGFEDEKAALMKRLSK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase 2, GPI 2, Phosphoglucose isomerase 2, PGI 2, Phosphohexose isomerase 2, PHI 2.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_LISMC
Sequence: MGDKIAVIPGTFDPITNGHLDIIERAAKIFDVLYVSVLNNSSKKPLFTIEERMEMIRQVTAHLPNVQVESASGLTVDYAATRGATAIVRGLRAVSDFEYEMQIASMNRTLNAEIETFFIMTNTKYSFLSSSMVKEVAQYQGDISELVPEIVNEQVQAKFK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_LACGA
Sequence: MTKGILGRKVGMTQIFTKNGILVPVTVIEATPNVVLQVKTNESDGYEAVQVGYQDMREVLSNKPAKGHAAKAKTSPKRFIREIRDVELKDYEVGSEITVDSFSEGDVVDVTGTTRGHGTQGNIKRWGQSRGPETHGSRYHRIPGSMGSIINRVPKGKKLPGHMGGKKVTVQNLVIEKVVPEKNVLLVKGNVPGAKNSLIFVKSAAKAAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: HM19_XENLA
Sequence: QADVGLALGTLYGNVFSQTTICRFEALQLSFKYMCKLKPLLNKWLEETDSTTESPINLDKIAAQGRKRKKRTSIEVGVKGALENHFLKCPKPSAHEITSLADSLQ
What are the official names of this protein?
Homeotic protein NRL-19, XlNRL-19.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SLYX_PSEE4
Sequence: MSLEMRIVELETRQAFQDDTIQALNDEVVEQSRVIERLQLQVAELIKRYEEMVGQYAGGGEEPPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: NU1C_ATRBE
Sequence: MIIDTTEIETINSFSKLESLKEVYGIIWMLVPILTLVLGITIGVLVIVWLEREISAGIQQRIGPEYAGPLGILQALADGTKLLFKENLIPSTGDPRLFSIGPSIAVISIFLSYSVIPFGDHLVLADLSIGVFLWIAISSVAPVGLLMSGYGSNNKYSFLGGLRAAAQSISYEIPLALCVLSISLLSNSSSTVDIVEAQSKYGFLGWNLWRQPIGFIVFLISSLAECERLPFDLPEAEEELVAGYQTEYSGIKFGLFYIASYLNLLVSSLFVTVLYLGGWNLSIPYIFVPELFGINKRGKVFGTLIGIFITLAKTYLFLFIPIATRWTLPRLRMDQLLNLGWKFLLPISLGNLLLTTSSQLLSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: IF2_SALTO
Sequence: MAGKARVHELAKELGVESKTVLAKLKEMGEFVKSASSTVEAPVARRLRNAFVNNTGSPAPAAPPAATPPTPTPTPTPPRTPTPAPPPGGPRVTAKPMPPRRPGAPTPGPKPKGPVPGPPQSATPAAKPASAHDIEVAAAEARAAALKAEQEAAVKAAQAARQQQRDNVRREPPTEGGPRPGPRPGPGAMPPRPGSPAAGRSGGPTPGPGPRSGGRPPARGAGNNPFGIQGGQQRPPAAGAGGPRPSPASMPPRPSPASMPPRPSPASMPSQRPGRPGGPGSGRPGAGAGRPGGGGGGGGGYRGGGGGGGGGYRGGPGGGGGGGGGGGYRGGPGGGGGGFRGGPGGGRPGGGGRGRGGGAAGAFGRPGGRPTRGRKSKKQRRQEFDNLSAPTMSSGAPRGQGQTVRLSRGASLSDFADKINANPGSLVQEMFNLGEMVTATQSCSDDTLLLLGEHLGFVVQIVSPEDEDRELLAQFNIDLDAEVAEDRLVSRPPVVTVMGHVDHGKTKLLDAIRKANVVAGEAGGITQHIGAYQVHVPHDDQDRAITFIDTPGHEAFTAMRARGAQVTDIVILVVAADDGVMPQTIEALNHAKAADVPIVVAVNKIDKPDANPDKVRQQLTEYGLVAEEYGGDTMFVNVAAKPGTGIDSLLEAVLLTADASLELTAPTDGPAQGVAIEAHLDKGRGAVATVLVQKGTLRAGDSIVAGGAHGRVRAMLDENGNQVAEAGPSRPVLVLGLTAVPGAGDTFLAAEDDRTVRQIAEQRQARRRAAAFANSRGRATLETLMEQLKAGEKTSLNLVLKGDVSGSVEALEDALFNLDIPEEVQLRIIHRGVGSITESDVMLASASSEAVTIIGFNVRAANKVREMADREGVEIRYYTVIYQAIEEIEAALKGLLKPEYEEVELGTAEVREVFRSSKVGNISGCIVRSGLLRRNAKARLLRDGAVVADNLTIGSLKRFKDDATEVREGFECGLTLAGYNNVQVGDVIETFEMREKARV
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPPF_ECOLI
Sequence: MSTQEATLQQPLLQAIDLKKHYPVKKGMFAPERLVKALDGVSFNLERGKTLAVVGESGCGKSTLGRLLTMIEMPTGGELYYQGQDLLKHDPQAQKLRRQKIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSKEQRREKALSMMAKVGLKTEHYDRYPHMFSGGQRQRIAIARGLMLDPDVVIADEPVSALDVSVRAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKDQIFNNPRHPYTQALLSATPRLNPDDRRERIKLSGELPSPLNPPPGCAFNARCRRRFGPCTQLQPQLKDYGGQLVACFAVDQDENPQR
What is the function of this protein?
When a foreign outer membrane heme receptor is expressed in E. coli, DppABCDF can also transport heme and its precursor, 5-aminolevulinic acid (ALA), from the periplasm into the cytoplasm.
What are the official names of this protein?
Dipeptide transport ATP-binding protein DppF.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y4OB_SINFN
Sequence: MTEPVRGSSPSSDSARVPAELEAFFRIADRWRLSADDQIKLLGSPGRSTFFKWKKAGGTLPADTVERLSHILSIWKALRILFTIEERADDWIRRPNDFFDGASALDTMLQGRVVDIYRVRQYLDAQRGG
What are the official names of this protein?
Uncharacterized protein y4oB.
Protein: SYS_PECAS
Sequence: MLDPNLLRNELDAVAEKLLARRGFKLDVETLRKQEERRKVLQVETESLQAERNSRSKEIGAAKARGEDIEPLRREVNTLGEKLDTAKAELDQLQNEIRDLALTIPNLPDDSVPLGKDESQNKEVTRWGEPRKYDFAVRDHVELGEMAGGLDFAAAVKLTGARFVVMKGQIARLHRALAQFMLDLHTQQHGYQEAYVPYLVNHATLYGTGQLPKFGEDLFHTNPLSEEAESSQYALIPTAEVPLTNLVRDEILDEESLPLKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVELVQIVRPEDSMQALEELTTHAETVLQLLKLPYRKVLLCTGDMGFGSTKTYDLEVWLPAQDTYREISSCSNMWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVLENYQQADGRIEIPEVLRPYMGGLEFIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOE_PTEPE
Sequence: MKFLWAALVVTLLAGCRADVEEEVKLGQEPDRWQAKQPWEQALGRFWEYLRWVQTLSNKVKEELLNSQVTEELKLLIEETMKEVKAYKEELEKQVGPIAQETQARLSKELQAAQARLESDMEDVRTRLAQYRSEAQAALGQNTDDLQGRLASHLRKLRKRLLRDAEDLQKRLAVYQAGTHEAAERGVSAIHERLGPLMMEGPLQAIPPSQQLRERAEAWGQKVRGRLESVGSQARDRLDDMRDQMEELKAKVEEQASQVRLQAEAFQTRLKSWFEPLVQDMQRQWASLVEKVQSTLGISPSTKPSKTK
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: A1AT_NOTEU
Sequence: EELPDSKDRAXPLSASKXISPYMKEAIPMSIPPVIDFNKPFLIIXY
What are the official names of this protein?
Alpha-1-antiproteinase, Alpha-1-antitrypsin, Alpha-1-proteinase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECR_LACP7
Sequence: MDYYSTQISKLIEELGRLPGIGAKSAQRLAFHIINMPKEQVEHLAKTMLDARSNVKYCKVCQTLTDKEICPICSSEKRDQKVIMVVENTRDLAAYEKTGKFDGVYHVLHGAISPMLGIGPQDIKLKELMLRLQGDVDEVIIATNSSLEGEATAMYISKLIKPAGIKVSRIASGVPVGGDLEYIDEVTLLRALDGRIQL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PPAC_STACT
Sequence: MESTYIFGHKSPDTDAINSAIIMAEFEKLNGNDSAKAYRLGKVNPETQYALDYFKAEAPELLTEDLTDKDVILVDHNEFQQSADTIESAKIRHVVDHHRIANFHTAAPLYYRAEPLGCTATILYKMFKEQGFEIKPQIASLMLSAIISDSLLFKSPTCTEQDKAAAQALENIAGVDAQEYGLEMLKAGASTVDKSPVEIINADAKTFNMGDYSVRIGQVNTVDVNEILARQAELEQAITETLSGAEYDIFVLVATDILNSDSTILVLGKDKDKIAKAFDVELDNNTAFLPGVVSRKKQIVPPITAALS
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR16_PIPCE
Sequence: MVKLRLKRCGRKQRAVYRIVAIDVRSRREGRDLQKVGFYDPIKNQTYLNVPAVLYFLGKGAQPTGTVHDISKKAEIFKELRVNQTIRVNQTKGGLHI
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYC6_CYACA
Sequence: MFKNIIIVVAVTLCALFTNEHVVYSANLEHGEQIFSANCAACHAGGNNVIMPEKTLKAEALEANNIKNISAIANQVKNGKNAMPSFSRLSDSDIEDVANYVLSKADKGW
What is the function of this protein?
Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
What are the official names of this protein?
Cytochrome c6, Cytochrome c-553, Cytochrome c553, Soluble cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: RBFA_SALPC
Sequence: MAKEFGRPQRVAQEMQKEIALILQREIKDPRVGMMTTVSGVEMSRDLAYAKVFVTFLNDQDEAAVKNGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTNVVKHDEERRVNPDDSKED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_SINFN
Sequence: MFAVIKTGGKQYRVAADDVITIEKLEGVAGDKIEFTEILMVGVGADATIGAPFVEGAVVSAEVVDQGRAKKVIAFKKRRRQNSKRSRGHRQHQTVVRILDIAAAGGKAKKASKKTEAAAEAAN
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: IOD3_CHICK
Sequence: AACILLFPRFLLTAVMLWLLDFLCIRKKMLTMPTAEEAAGAGEGPPPDDPPVCVSDSNRMFTLESLKAVWHGQKLDFFKSAHVGSPAPNPEVIQLDGQKRLRILDFARGKRPLILNFGSCTUPPFMARLRSFRRLAADFVDIADFLLVYIEEAHPSDGWVSSDAAYSIPKHQCLQDRLRAAQLMREGAPDCPLAVDTMDNASSAAYGAYFERLYVIQEEKVMYQGGRGPEGYKISELRTWLDQYKTRLQSPGAVVIQV
What is the function of this protein?
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine).
What are the official names of this protein?
Thyroxine 5-deiodinase, 5DIII, DIOIII, Type 3 DI, Type III iodothyronine deiodinase.
What is the protein family that this protein belongs to?
Belongs to the iodothyronine deiodinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein.
Protein: PHOSP_MEASI
Sequence: MAEEQARHVKNGLECIRALKAEPIGSLAIGEAMAAWSEISDNPGQEQATCKEEEAGASGLSKPCLSAIGSTEGGAPRIRGQGSGESDDDTETLGFPSRNLQASSTGLQCYYVYDHSGEAVKGIQDADSIMVQSGLDGDSTLSGGDNESENSDVDIGEPDTEGYAITDRGPAPISMGFRASDVETAEGGEIHELLRLQSRGNNFPKLGKTLNVPPPPDPGRASTSETPIKKGTDARLASFGTEIASLLTDGATQCARKSPSEPSGPGAPAGNVPECVSNAALTQEWTPESGTTISPRSQNKGKGGDYYDDELFSDVQDIKTALAKIHEDNQKVISKLESLLLLKGEVESIKKQINKQNISISTLEGHLSSIMIAIPGLGKDPNDPTADVEINPDLKPIIGRDSGRALAEVLKKPVASRQLQGMTNGRTSSRGQLLKEFQLKPIGKKMSSAVGFVPDTGPASRSVIRSIIKSSRIEEDRKRYLMTLLDDIKGANDLAKFHQMLMKIIMK
What is the function of this protein?
Essential component of the RNA polymerase and the nascent chain assembly complex.  Also required during RNA synthesis.
What are the official names of this protein?
Phosphoprotein, Protein P.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus P protein family.
Protein: MNHE2_STAAN
Sequence: MNQIVLNIIIAFLWVLFQDEDHFKFSTFFSGYLIGLIVIYILHRFFSDDFYVRKIWVAIKFLGVYLYQLITSSISTINYILFKTKDMNPGLLSYETRLTSDWAITFLTILIIITPGSTVIRISQDSKKFFIHSIDVSEKEKDSLLRSIKHYEDLILEVSR
What are the official names of this protein?
Putative antiporter subunit mnhE2, Mrp complex subunit E2, Putative NADH-ubiquinone oxidoreductase subunit mnhE2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL17_GLUOX
Sequence: MRHGVSGRKLNVTSSHRAAMFRNMAVALIKHEQITTTLPKAKELRPVVEKLITLGKRGDLHARRQAFAQLRDDAVVTKLFSAVAERYKGRAGGYSRVLKAGVRYGDNADMAVIELVDRDVAAKGQDSGPKQNVAEEQEAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SYD_ECO24
Sequence: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEAILDRTAAQDGDMIFFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPTALAELSIQVVKKAENN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_BUCCC
Sequence: MSITRKEILDAISEMSIKNIMKLISNIEKKFNISSNISLNSTQTIQEKVPEEKTAFTVKLNAIGPNKVAIIKIIRSTTGLGLKESKDLVESAPTIIKENINKQDAESLKKNLIDSGAEAEIT
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ORN_PSEAB
Sequence: MQNPQNLIWIDLEMTGLDPDRDVIIEMATIVTDSDLNTLAEGPVIAIHQPEEILAGMDEWNTRQHGQSGLTQRVRESTVSMAEAEAQTLAFLEQWVPKRSSPICGNSICQDRRFLYRHMPRLEGYFHYRNLDVSTLKELAARWAPQVRESFKKGNTHLALDDIRESIAELRHYRDHFIKL
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATRX_NOTEU
Sequence: KDDFKGPEFRSRSKMKTENLKKRGEGLHGIVSCTACGQQVNHFQKDSIYRHPTLKVLICKNCYKYYMSDDISRDADGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSAIMDENSQWYCYICRPEPLLDLVTACHSVFKNLEQLLQQNKKKIKVESEKSNKLFEHTHRFSPKKNVSSCNGEEKKSDDAYSGSVTYSFTALMVPKDIVKKTKKLVETTASMNTSFVRFLKQASENPEVSPVTKLRQLKAFKSVLNDVKKVHLALEGSLNVEIRTLEALNKETVTKEHKAEGVKPDTEVTKVEVYCAPKKKDFSKCATKLSVKQVDSEINGQSLPVVGQPVHKTTSAEDKKSSRKDPHFEPANTSEALDMDFSLLIFPLIFIFFELSSCYFLLSSSFLFQSCFSLTSIFLLQIVDLLFFKFYFFFKISLISIFLLQIVHLLFSLNLFSSKLFFLFLNFFSFFKLSTFQIPNFSSKMLFPDFYLPLPILLFL
What is the function of this protein?
Involved in transcriptional regulation and chromatin remodeling.  Facilitates DNA replication in multiple cellular environments and is required for efficient replication of a subset of genomic loci.  Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures.  May help stabilizing G-rich regions into regular chromatin structures by remodeling G4 DNA and incorporating H3. 3-containing nucleosomes.  Catalytic component of the chromatin remodeling complex ATRX:DAXX which has ATP-dependent DNA translocase activity and catalyzes the replication-independent deposition of histone H3. 3 in pericentric DNA repeats outside S-phase and telomeres, and the in vitro remodeling of H3. 3-containing nucleosomes.  Its heterochromatin targeting is proposed to involve a combinatorial readout of histone H3 modifications (specifically methylation states of H3K9 and H3K4) and association with CBX5.  May be involved in transcriptional regulation of telomeric repeat-containing RNA (TERRA).  Acts as negative regulator of chromatin incorporation of transcriptionally repressive histone MACROH2A1, particularily at telomeres.  Binds to zinc-finger coding genes with atypical chromatin signatures and regulates its H3K9me3 levels.  Forms a complex with ZNF274, TRIM28 and SETDB1 to facilitate the deposition and maintenance of H3K9me3 at the 3' exons of zinc-finger genes (By similarity).
What are the official names of this protein?
Transcriptional regulator ATRX, ATP-dependent helicase ATRX, X-linked nuclear protein.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere. Nucleus, PML body. Note=Associated with pericentromeric heterochromatin during interphase and mitosis, probably by interacting with CBX5/HP1 alpha. Colocalizes with histone H3.3, DAXX, HIRA and ASF1A at PML-nuclear bodies (By similarity).
Protein: FHL1_HUMAN
Sequence: MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVSHPVSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPGLVKAPVWWPMKDNPGTTTASTAKNAP
What is the function of this protein?
May have an involvement in muscle development or hypertrophy.
What are the official names of this protein?
Four and a half LIM domains protein 1, FHL-1, Skeletal muscle LIM-protein 1, SLIM, SLIM-1.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. Cytoplasm, cytosol. Note=Predominantly nuclear in myoblasts but is cytosolic in differentiated myotubes.
Protein: RPOT1_ARATH
Sequence: MWRNILGRASLRKVKFLSDSSSSGTHYPVNRVRGILSSVNLSGVRNGLSINPVNEMGGLSSFRHGQCYVFEGYATAAQAIDSTDPEDESSGSDEVNELITEMEKETERIRKKARLAAIPPKRVIAGMGAQKFYMLKQRQVKMETEEWERAARECREILADMCEQKLAPNLPYMKSLFLGWFEPVRNAIQDDLDTFKIKKGKIPYAPFMEQLPADKMAVITMHKMMGLLMTNAEGVGIVKLVNAATQIGEAVEQEVRINSFLQKKNKKNATDKTINTEAENVSEEIVAKETEKARKQVTVLMEKNKLRQVKALVRKHDSFKPWGQEAQVKVGARLIQLLMENAYIQPPAEQFDDGPPDIRPAFKQNFRTVTLENTKTSRRYGCIECDPLVLKGLDKSARHMVIPYLPMLIPPQNWTGYDQGAHFFLPSYVMRTHGAKQQRTVMKRTPKEQLEPVYEALDTLGNTKWKINKKVLSLVDRIWANGGRIGGLVDREDVPIPEEPEREDQEKFKNWRWESKKAIKQNNERHSQRCDIELKLEVARKMKDEEGFYYPHNVDFRGRAYPIHPYLNHLGSDLCRGILEFCEGKPLGKSGLRWLKIHIANLYAGGVDKLAYEDRIAFTESHLEDIFDSSDRPLEGKRWWLNAEDPFQCLAACINLSEALRSPFPEAAISHIPIHQDGSCNGLQHYAALGRDKLGADAVNLVTGEKPADVYTEIAARVLKIMQQDAEEDPETFPNATYAKLMLDQVDRKLVKQTVMTSVYGVTYSGARDQIKKRLKERGTFEDDSLTFHASCYAAKITLKALEEMFEAARAIKSWFGDCAKIIASENNAVCWTTPLGLPVVQPYRKPGRHLVKTTLQVLTLSRETDKVMARRQMTAFAPNFIHSLDGSHMMMTAVACNRAGLSFAGVHDSFWTHACDVDVMNTILREKFVELYEKPILENLLESFQKSFPDISFPPLPERGDFDLRKVLESTYFFN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the phage and mitochondrial RNA polymerase family.
What are the subcellular locations of this protein?
Mitochondrion.