PharMolix/UniProtQA huggingface dataset:
Protein: ARP2_BOVIN
Sequence: MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKDLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR
What is the function of this protein?
ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility.  Seems to contact the pointed end of the daughter actin filament.  In podocytes, required for the formation of lamellipodia downstream of AVIL and PLCE1 regulation.  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
What are the official names of this protein?
Actin-related protein 2, Actin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection. Nucleus.
Protein: BLI4_NEUCR
Sequence: MSTKLCQRIARTATLSPTSLVPRSSRLIPIVSSAAVRPSSAIPTRRPFSTTESRYLANVQAGMDKIRDAIAENFGGPAHNIGTTSFSLDDTPDLSGKVAVITGGSEGIGYGVAYTLIKHNLSKLFILSRKREVFDGALASIASELGQDKADRVHWIQCNLEDWAQTAVVAEQIKKDTDRLDILVNNSGRGIMTAGLTSYGVDKHMATNHMGHVVLTSHLLPLLQKTAEETGETVRISNQSSNLHSAAPKGTQFKSLEEINEDVGPNGQYGRSKLAGILYARYFDREVTRKMEGSKGRVVMNATHPGFVSTKQSVKDIHEPYPISGFAISHLAEPFKKDQFEGAVPTVYAVTMANEGGQWICAPAKAEAGTDLAQSDELADNLMELTRKIISEKTWPKSVAKGCPMDDVVVHV
What is the function of this protein?
May play a role as an NAD-dependent dehydrogenase in the mitochondria.
What are the official names of this protein?
Putative oxidoreductase bli-4, mitochondrial, Blue light-induced protein 4.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HIS5_EMENI
Sequence: MPTVHLLDYVAGNVRSLVNAINKVGYEVEWVRSPSDLKDVEKLILPGVGHFGHCLSQLSSGGYLQPIREHIASGKPFMGICVGLQSLFESSEEDPNIPGLGTIPARLRKFDAKTKSVPHIGWNSATDTRIDSTGGQTFYGLSPSSKYYYVHSYAAPYEPGILEKDGWLVATASYGEEKFIGAIARDNIFATQFHPEKSGQAGLRTLRAFLDGAQLHSVTLEDSILTGEKNGLTRRIIACLDVRTNDVGDLVVTKGDQYDVREKDGADAGGQVRNLGKPVDMAKKYYEQGADEVTFLNITSFRNCPLADLPMLEILRRTSETVFVPLTIGGGIRDTVDTDGTHIPALDVASMYFKSGADKVSIGSDAVVAAEDYYAAGKVLSGKTAIETISKAYGNQAVVVSVDPKRVYVSQPEDTKHRTIETKFPNAAGQNFCWYQCTIKGGRETRDLDVCQLVQAVEAMGAGEILLNCIDKDGSNSGFDLELINHVKAAVKIPVIASSGAGMPKHFEEVFDQTTTDAALGAGMFHRGEYTVGEVKQYLEDRGFLVRRFEPDV
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR.  The ammonia is channeled to the active site of the cyclase domain.
What are the official names of this protein?
Imidazole glycerol phosphate synthase hisHF, IGP synthase, IGPS, ImGP synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HisA/HisF family.
Protein: CLPP2_PARXL
Sequence: MTFRAQMLDTLTSQSSRDLEAQALGLVPIVVETSGRGERSYDIYSRLLKERIVFLVGEVNDQTANLVVAQMLFLESENPDKDISFYINSPGGSVSAGMAIYDTMQFIKPDVSTLCMGLAASMGAFLLAAGAKGKRFALPNSRVMIHQPLGGARGQASDIEIQAREILYLKERLNHLLAHHTGQPVERIARDTDRDNFMSGDDAQAYGLVDQVAHKRP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLR_ECO57
Sequence: MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVVEKDRLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
What are the official names of this protein?
Tol-Pal system protein TolR.
What is the protein family that this protein belongs to?
Belongs to the ExbD/TolR family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL5_STRP6
Sequence: MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDAVSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTTANTDEESRELLKGLGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PSBN_CHLRE
Sequence: MESPAFFFTFFLWFLLLSVTGYSVYVSFGPPSKKLRDPFEEHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HPF1_MOUSE
Sequence: MVGGGGKRRTAGAGPQCEKTVEVKKSKFSEADVSSDLRKEVENLYKLSLPEDFYHFWKFCEELDPEKPADALATSLGLRLVGPYDILAGKHKMKKKPTGLNCNLHWRFYYDPPEFQTIIIGDNKTQYHMGYFRDSPDELPVYVGTNEAKKNCIIIQNGDNVFAAIKLFLMKKLKEVTDRKKISILKNIDEKLTEAARKLGYSLEQRTVKMRQRDKKVVTKTFHGAGLVVPVDKNDVGYRELPETDADLKRICKAVVDAASDEERLKAFAPIQEMMTFVQFANDECDYGMGLELGMDLFCYGSHYFHKVAGQLLPLAYNLLKRDLFAKIIEDHLASRSEENIDQLAG
What is the function of this protein?
Cofactor for serine ADP-ribosylation that confers serine specificity on PARP1 and PARP2 and plays a key role in DNA damage response.  Initiates the repair of double-strand DNA breaks: recruited to DNA damage sites by PARP1 and PARP2 and switches the amino acid specificity of PARP1 and PARP2 from aspartate or glutamate to serine residues, licensing serine ADP-ribosylation of target proteins.  Serine ADP-ribosylation of target proteins, such as histones, promotes decompaction of chromatin and the recruitment of repair factors leading to the reparation of DNA strand breaks.  Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage.  HPF1 acts by completing the active site of PARP1 and PARP2: forms a composite active site composed of residues from HPF1 and PARP1 or PARP2.  While HPF1 promotes the initiation of serine ADP-ribosylation, it restricts the polymerase activity of PARP1 and PARP2 in order to limit the length of poly-ADP-ribose chains.  HPF1 also promotes tyrosine ADP-ribosylation, probably by conferring tyrosine specificity on PARP1.
What are the official names of this protein?
Histone PARylation factor 1.
What is the protein family that this protein belongs to?
Belongs to the HPF1 family.
What are the subcellular locations of this protein?
Chromosome. Nucleus. Note=Localizes to DNA damage sites; chromatin localization is dependent on PARP1 and PARP2.
Protein: NDUA7_HUMAN
Sequence: MASATRLIQRLRNWASGHDLQGKLQLRYQEISKRTQPPPKLPVGPSHKLSNNYYCTRDGRRESVPPSIIMSSQKALVSGKPAESSAVAATEKKAVTPAPPIKRWELSSDQPYL
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7, Complex I-B14.5a, CI-B14.5a, NADH-ubiquinone oxidoreductase subunit B14.5a.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA7 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: NU4M_ZAGBR
Sequence: MLKILLPTVMLLPLISFSKKEWMWINSSAYSILISSLSLLTLNQHMDLGLNFNLNFFTDPLSSPLLVLSCWLLPLMILASQFHLMNESINHKRMYLILLVSLQIALLMAFSAVEFMMYYILFETTLIPTLIIIARWGNQTERLNAGLYFLFYTLLGSLPLLVALIFTQAQMGSLHILLLTLTPNPLLNSWSNDILWLACMMAFLVKMPLYGFHLWLPKAHVEAPIAGSMVLAAILLKLGGYGILRIIIILEPISKFMAYPFIILATWGMIMTSSICLRQTDLKSLIAYSSISHMGLVVAASLIQTPWGFMGATAMMIAHGLTSSMLFCLANTNYERAHSRTMVLIRGLQMVLPLMSSWWLLASLTNLGLPPTINLISELMIIVSTFSWSNFTLILLGLNTVITAIYSLYMLISVQRGKMTTHSLSINPTFTREHMIMALHLLPLILLTLNPKLILGVAY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: Y3475_LEPIC
Sequence: MFDKIKNFSEILSNMGSFREKMEEVKKRIASIRVVGDAGAGMVTVTASGEGQITNVFINKQLFDADDNKMLEDLVMAATNDALKKAKEATAYEFQSASGGLDFSEISKMFGGKFG
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein LIC_13475.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS6E_THEKO
Sequence: MATFKLVISNPKNGVAKQVEISGPEADKLIGRRIGEEIPASELGLNLSEIFGEEIPADAKLKITGGTDKDGFPMRPDVHGPRRVKILLSRGPGFRPRERGERRKKTVHGNTISPNIVQVNMKIVF
What are the official names of this protein?
30S ribosomal protein S6e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: PRFB2_ARATH
Sequence: MLSLIIRRSRSRFIIHGIKISCNSLSAVDSSSSVLVSRRTFSSTPALSYFGFNYGKISNLNQRFGNYAYSGSSFASSTRSLSSEAVAVAATCDGLTVERIIANQWPILDENEGDWKSHAAAIAQSIQVIKRRLQWKKLLVRLKVLSAELNKSDLWDDPTHAGKISREHGSLTGKMKGVMTFERELLEHIDMLKLAKEENDSELESETLKALIDMRRVSKEKELEALLSADNDPCSCYIEVQAGAGGTESNDWAAMVMEMYKTWAQRRKFSVTVVDEAPGEIAGIKRATIKVNGEYAYGYAKAEVGVHRLVRISPFDSGKRRHTSFAAVAVIPILGDGSTRVEINDSDLRIERFRSGGAGGQHANTTDSAVRIVHIPTGITATCQNERSQHSNKASAMAVLQSRLDQLEMARQTAMNAQHTQSLTEISWGNQIRTYVLHPYRMVKDLRTNYEVSDPDSVLEGDLDGFILSFLSSSLDKDDPEH
What is the function of this protein?
Directs the termination of translation in response to the peptide chain termination codon UGA.  Required for the proper translation, stability and normal processing of UGA-containing polycistronic transcripts in chloroplasts.
What are the official names of this protein?
Peptide chain release factor PrfB2, chloroplastic, AtPrfB2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RPOY_STRPB
Sequence: MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVEDNTYYNVEFIELLSDKHLDYEKETGVFELTEF
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: RL22_AERS4
Sequence: MEAIAKHRYARTSAQKARLVADQVRGLSVDKALNILTFSPKKAAVLVKKVLESAIANAEHNEGADIDALRVATIMVDEGPSMKRIRPRAKGRADRILKRTAHITVVVSDAKAGR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PROA_SHISS
Sequence: MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILNANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSGLRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQDALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDESVEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQMAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIREHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGIGDYTIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_LEPIN
Sequence: MSETQKENPYSSTVLLPKTDFPMKADLAKREPAQIQSWKSGQIFRKMKEQRKGKKEFVLHDGPPYANGNFHLGHSLNKIVKDIIIKSKSLAGFYADMIPGWDCHGLPIEVQVLKNLGKKARETGPEELRRLCRNYAEEFVGKQGEDLSRFLCFWEEDRIYKTMSPGFEAKIVEVFGELFQNGYVYRGKKPVYWSIDLATAHAEAEIEYYPHVSPSIYVKFPIVGEQKKFCLIWTTTPWTLPANLGICFNRKIEYSFFKTESGEELILADGLAESVTSTTGVSLNKVKSISSDELSVLKFQHPFMDRISISLFGDHVTLDAGTGCVHTAPGHGQDDYKVGLAAGLEPFSPVDDYGKYTDEFPLMQGKKVFDANPEIIQLLKDKGLLLHHSEFEHSYPHSWRSKKPLIFRATPQWFFKMDFNELREKSLSAIDGVQWIPSWGITRIRSMVETRPDWCLSRQRNWGVPIPAFTCESCGQTHIDDVSIQFFTKMVREKGIEIWYSEKAADLLPPGTKCGKCGSDSFKKGNDILDVWFDSGVSSFAVLGERKDEPPADLYFEGSDQHRGWFQSSLWPSMALRGIPPYKTVLTHGYVLDEKGHPMSKSLGNGIDPTADVIQIYGADILRLWVSSLDFRDDIKVGKESLKIVSEQYRKIRNTFRYLLGNLDGHTSEQNLPFEELEELDLFYLSKLSQFAEDVIANYEAYQFHQIYQKLILFCTVTLSQDYFDMIRDRMYCDARNSKTRKSSATALQYILETLCILTAPILSFTAEEVWVSNGKKDSVFLQNFPDLKFWKNQNLEEKFESVLQVREVVQKALEIARQENKLGKSLEAGLEIVSKNGTNLTKILPKETLEILFVVSQVHEKNPGLDVLSFYENEKFSVKVLKPVQVECPRCWRHTEDISKEGDLCGRCKSVVG
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMER2_CHICK
Sequence: MDSHCDCAEPPAAEQPSGKINKTAFKLFKRRKSGGTMPSIFGVRSKGGEGKGASKTGMVRSRTHDGLADAVLESGKKEDAGGGEAQGKDAPSRAAGGLGGSASSSVAKSHSFFSLLRKNGRPENGKAAENAEQRAGGRQKKGLKGIFSSMRWHRKDKIGKEERGEASEIPSGLIMPGSLTASLECIKEETPKPLSETPNGAGDTGVESQQEKRGGDACVSAEEPQAGGGESRDSKTPPGEDPAAAARRLEELCGERPDPGAGEVGTAKDAAITGDIPITTIPPVEPHCDSGQETAAAPDPSSVDPPSEQSIDRICLMFADVTSLKSFDSLTGCGDIIADQEEDVGGGSGGCEKSTPGAGKLGAPKKHPTMVAYQGGGEEMASPDQVDDTYLQEFWDMLSQTEETETGGGGGGGGGTKTPEGLKENRGTEGAQNRVAVKRGGLNQIPIHLNNKEEQKGREKEQHEGVPNSDEGYWDSTTPGPEEDSTTSIQKETLPRDSYSGDALYDLYAEPDENPPGGPPEEEVTCMPRSKPVSPITTTCSLKTPSSTVKDSKIPISIKHLASHPASHGTDTSNSHHVAHHHLAKSEMHRTKIPVSKVLVRRVSNRGLAGTTVKAATHQDSAKK
What is the function of this protein?
Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning.  Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex (By similarity).
What are the official names of this protein?
APC membrane recruitment protein 2, Amer2, Protein FAM123A.
What is the protein family that this protein belongs to?
Belongs to the Amer family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Translocates to the cell membrane following binding to PtdIns(4,5)P2.
Protein: HSP1_ANTSW
Sequence: MARYRRHSRSRSRSRYRRRRRRRSRHHNRRRTYRRSRRHSRRRRGRRRGYSRRRYSRRGRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YHBQ_SALPB
Sequence: MTPWYLYLIRTADNALYTGITTDVARRYRQHQTGKGAKALRGKGELTLAFAAQVGDRSLALRIEYRIKQLTKRQKERLVTEREAFEALLSSLQTPVLKND
What are the official names of this protein?
UPF0213 protein YhbQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: RLMKL_XANOR
Sequence: MKFFASCAKGLEYLLADELLALGASKATATISGVNVEGELRDAQRAVLWSRLASRVLWPLSEFDCPDEDALYAGVAELPWDAHLSVGHTLSVDAHVSGTAITHARYAAQRIKDAVVDTMRRQGLERPSVDVESPDLRLNLSLRKGRATISVDLGGGPLHRRGWRMAQNEAPLKENLAAAVLMRGGWPRAYADGGGLLDPMCGSGTLLIEGALMAADVAPGLQRYGSDLPSRWRGFDRNGWQQLVSEARERDSVGRAALKQVIHGSDMDPHAIRAAKENAQVAGVAEAIWFGVCEVGELQTPPQATGVVVCNPPYDERLAADAALYRRLGDTLQCAVPQWRASLLCGNAELAYATGLRAGKKYQLFNGAIECALIVCDPIAVPRRTPLAAPTALSEGAQMVANRLRKNLQKFKKWRAREGVECFRAYDADLPEYSAAIDVYQQADGDRRIFLHVQEYAAPATIPEADVRRRLNELLAAAREVFEVPAERVALKSRERGKGGSKYGRFEQRNEIVHVREHGALLRVNLFDYLDTGLFLDHRPLRGTMAQQSRGRRFLNLFCYTGVASVEAAVAGAASTTSVDLSGTYLQWCADNLALNGLAGSKHKLVQADALAWLEAERAHFDVIFCDPPTFSNSARAEDFDIQRAHVRLLRAAVARLAPGGVLYFSNNFRRFKLDEEGVAEFAQCEDISPSTIDPDFERHARIHRAWRLTA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTN9_MOUSE
Sequence: MEPATAPRPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAVELFHCYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSAQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYVKIDLATWNFQFLPQVNGHPDPFDEIILSSLPPALDWDSVHVPGPHAMTIQELVDYVNTRQKRGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSMAVGNLGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVPSGHSLLAMDGQ
What is the function of this protein?
Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus.
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 9, Protein-tyrosine phosphatase MEG2, PTPase MEG2.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_NITMU
Sequence: MPSRPDKNLETFPNPTQERDYHIHMEIPEFTCLCPKTGQPDFATLILDYIPDKKCVELKSLKLYIWSFRDENAFHEAVTNRIVDDLATALQPRYLRLTAKFYVRGGIFTTVVAEHRHSGWTPLPSVDLFHFDSQPSTRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_SHEPC
Sequence: MQPFTTHTGLAVMIDSTNIDTDQIIPKQFLSKVTRDGFGVHLFHDWRYLDDAGDVPNPEFSLNQPRYKGASILVSQENFGCGSSREHAPWALADFGLRAIIAPSFADIFYGNSINNGLLPVALTHAQVRQLMDEVAAEEGAQITVDLTSCKVISPSGAEFSFTLAESARHKLLNGLDAIGLTLSHAAQISQYETQIQGWRS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: SECB_RICAH
Sequence: MSTINTDTNEAMPHISVNAQYIKDLSLENPSAPSSLAALDQRPQIDLSLDINITNLSEENFYEVELNIEATARNEKYKLFHIELKYAGVFNLINIDSEQHPILLSVHCPAMIFPFARKIISSCTQDAGFQPLMIDPIDFGALYHKKMSEHQN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_STRP8
Sequence: MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATIYLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQTKINQKPKQQALNSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHLLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQSLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNITPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQIDTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQNIVLARQVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKIK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.