PharMolix/UniProtQA huggingface dataset:
Protein: ZN711_MOUSE
Sequence: MESGGGSLGLHTSDARMAHTMIMQDFVAGMAGTAHIDGDHIVVSVPEAVLVSDVVTDDGITLDHGLAAEVVHGPDIITETDVVTEGVIVPEAVLEADVAIEEDLEEDDGDHILTSELITETVRVPEQVFVADLVSGPDGHLEHVVQDCVSGVDSPTMVSEEVLVTNSDTETVIQAGGGVPGSTVTIKTEEDDDDDVKSTSEDYLMISLDDVGEKLEHMGNTPLKIASDGSQEDVKEDAFGSEVIKVYIFKAEAEDDVEIGGTEIVTESEYSSGHSVAGVLDQSRMQREKMVYMAVKDSSQEQDDIRDERRVSRRYEECQAPGNTFDSALENRNTTAAQYLQICDSMNTNKVLKQKIKKRRRGETRQWQTAVIIGPDGQPLTVYPCHICTKKFKSRGFLKRHMKNHPDHLMRKKYQCTDCDFTTNKKVSFHNHLESHKLINKVDKTHEFTEYTRRYREASPLSSNKLILRDKEPKMHKCKYCDYETAEQGLLNRHLLAVHSKSFPHVCVECGKGFRHPSELKKHMRTHTGEKPYQCQYCAFRCADQSNLKTHIKSKHGSNLPYKCEHCPQAFGDERELQRHLDLFQGHKTHQCPHCDHKSTNSSDLKRHIISVHTKDFPHKCEVCDKGFHRPSELKKHSDIHKGRKIHQCRHCDFKTSDPFILSGHILSVHTKDQSLKCKRCKRGFRQQNELKKHMKTHTGRKIYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEFCKKGFRRPSEKKQHIMRHHKETLM
What is the function of this protein?
Transcription regulator required for brain development.  Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activated expression of genes involved in neuron development, such as KDM5C.  May compete with transcription factor ARX for activation of expression of KDM5C.
What are the official names of this protein?
Zinc finger protein 711.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YRO7_CAEEL
Sequence: MASSKKQKKKMHRPHNRKLMIRDLPVGAAYLLHPSLRGILLSRPKRWNSGSPSHRIAVNLVRKYKKQLKPRVLPFFCDHCRLASRTLLHIKEHVCDKEEKRKAARKEESRKFADYDVTNEIKLATNSEKQWRFNAMAVLEQTLRPNKVAPKKVEIEEDPGIDQLLDSEPDQEFYDAQEQEFEDDTPHYPIKDVLVPSSQPPRPKVTLKSSECLGHNDAGVFCFNCKGSFDSYNQFQLHLNEDYNDGKCNRALPEYYYVQRHDRTHMFDKRYKHSVQHHKPIKRDISHIQCTLCKAVNFASTGDLYAHMVKCASSTTNEDKESAIDCPTAFGYGMPPSFNACQYVFPDPAKERYSRNSRGSKEPVES
What are the official names of this protein?
Uncharacterized protein R07G3.7.
Protein: MICA2_MOUSE
Sequence: MGENEDEKQAQASQVFENFVQATTCKGTLQAFNILTCLLDLDPLDHRNFYSQLKSKVNTWKAKALWHKLDKRGSHKEYKRGKACSNTKCLIVGGGPCGLRTAIELAYLGAKVVVVEKRDTFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILFKVALMLGVEVHVNVEFVRVLEPPEDQENQKVGWRAEFLPADHALSDFEFDVIIGADGHRNTLEGFRRKEFRGKLAIAITANFINRNSTAEAKVEEISGVAFIFNQKFFQDLKEETGIDLENIVYYKDSTHYFVMTAKKQSLLDKGVILNDYIDTEMLLCSENVNQDNLLSYAREAADFATNYQLPSLDFAINHNGQPDVAMFDFTSMYASENAALMRERQAHQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMVKSWDQGTPPLEVLAERESLYRLLPQTTPENINKNFEQYTLDPATRYPNLNLHCVRPHQVKHLYITKEMDRFPLERWGSVRRSVSLSRRESDIRPNKLLTWCQQQTKGYQHVRVTDLTTSWRSGLALCAIIHSFRPELINFDSLNEDDAVENNQLAFDVAKREFGILPVTTGKEMASTQEPDKLSMVMYLSKFYELFRGTPLRPMDSWRKNYGENADFGLGKTFIQNNYLNLTLPRKRTPRVDTQTEENDMNKRRRQGFNHLEELPSFSSRSLGSSQEYAKESGSQNKVKHMANQLLAKFEENTRNPSVVKQDCRRVSGIGKPVLCSASRPPGTSCCPKLEESTPRLPPPLKRQFSSTVATGQVLRELNQVPASGECPSRPWRARAKSDLQLGGVENLATLPRTCQGALALSGVLRRLQQVEEKVLQKRAQNLANREFHTKNIKEKAAHLASMFGHGDLPQDKLLSKRVPHAHPPSPPSCLPSPHPAAASSPPAADSVSPARKVVALNHRLPPPLHLTVGKVSSGIGAAAEVLVNLYLNDHRPKTQATSPDLESPRKAFPLSLGGRDTCYFCKKRVYMIERLSAEGHFFHQECFRCSVCSATLRLAAYAFDCDEGKFYCKPHFVHCKTSSKQRKRRAELNQQREEEGTWQEQEAPRRDVPTESSCAVAAISTPEGSPPDEPISPKKPKSVPEPNPRDVEAEATSPRPSEWTSVRISPGEDTVRQDVLAVRVLVTSEDSSSDTESDYGSITAPCAGAYEERPQLPESPPLSKPLTRHISLRENLTQPVSLLHEEPQALPALQRAHSLQSPTPSKYQNWRRRFQSNSTPMNQRAPSPPKEPPPPPSLSSSSSLPSSFSSASVPGHTADDSSSPQVTYNLHSPQISRGDVSPTPIYLRRARAQGIVKEIPLYLPHSPMLESTEDCLVEPGRESLRSPEEISSSEGCQEARALGNTRSIQHPILGKDQYLPNQNLALGAAGNPGDPREESRMGQPGGPELSKERKLGLKKLVLTEEQKNKLLDWSDCTQEHKTGEQLSQESAENIRGGSLKPTCSSTLSQAVKEKLLSQKKALGGMRTPAVKAPQEREVPPPKSPLKLIANAILRSLLHNSEAGKKTSPKPESKTLPRGQPHARSFSLRKLGSSKDGDQQSPGRHMAKKASAFFSLASPTSKVAQASDLSLPNSILRSRSLPSRPSKMFFSTTPHSKVEDVPTLLEKVSLQDATHSPKTGASHISSLGLKDKSFESFLQECKQRKDIGDFFNSPKEEGPPGNRVPSLEKLVQPVGSTSMGQVAHPSSTGQDARKLEGGEGGSSLVSSLVLVSDPVAPVTEATSSPTSSSAEEEADSQLSLRIKEKILRRRRKLEKQSAKQEELKRLHKAQAIQRQLEEVEERQRTLAIQGVKLEKVLRGEAADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLRQKMLKDEGQKDENDLKEEQEIFEEMMQVIEQRNKLVDSLEEQRVKERTQDQHFENFVLSRGCQLSRT
What is the function of this protein?
Methionine monooxygenase that promotes depolymerization of F-actin by mediating oxidation of residues 'Met-44' and 'Met-47' on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization (PubMed:23911929, PubMed:23927065).  Regulates the disassembly of branched actin networks also by oxidizing ARP3B-containing ARP2/3 complexes leading to ARP3B dissociation from the network.  Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription.  Does not activate SRF:MKL1/MRTF-A through RhoA (By similarity).
What are the official names of this protein?
[F-actin]-monooxygenase MICAL2, ERK2-binding testicular protein 1, MICAL C-terminal-like protein, Mical-cL, Molecule interacting with CasL protein 2, MICAL-2, mMical2.
What is the protein family that this protein belongs to?
Belongs to the Mical family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KAX69_OPICA
Sequence: MNAKFILLLLVVTTTTLLPDAKGAEIIRCSGTRECYAPCQKLTGCLNAKCMNKACKCYGCV
What is the function of this protein?
Inhibits Kv1. 2/KCNA2 and Kv1. 3/KCNA3 voltage-gated potassium channels (PubMed:29483648).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 6.9, OcKTx4.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 06 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y104_ADE07
Sequence: MSEGKSVPDHDFEELILEVDVITGPLFPELEVRPLLVGGIGQSESNIIEEDLTGPGHEISGDFKRLRDLCSVIDNLSGQDDLIKAIDVVPHYVQF
What are the official names of this protein?
Uncharacterized 10.4 kDa early protein.
Protein: OPUBB_BACSU
Sequence: MHHIVQFLQTNGGELLYKTYEHITISLIAVILGVLVAVPLGVVLTRMKKGAGTIIGIVNIIQTLPSLAILAFFIPLLGVGKVPAIVALFFYSVLPILRNTYTGIRGVNKNLLESGKGIGMTPAEQVRLVELPLAAPVIMAGIRTSTIYLIGWATLASFIGGGGLGDYIFIGLNLYQPEYIIGGAVPVTILAIVIDYVLAVAERKLTPAGMQRLKELS
What is the function of this protein?
Involved in a high affinity multicomponent binding-protein-dependent transport system for choline; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Choline transport system permease protein OpuBB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASTD_LEGPC
Sequence: MSKLQIIQSKGQYINGEWIKGNGLILESTNPASGTLLWQGNNATDEEIANACYVAHRALKSWANTSFEERARYTKAFVEQVEKNREQLARLISLETGKPLWESQTEVSSVIGKVNLSIQAYQERTWPKQTETAEANACLRFKPHGIVVVLGAFNFPAHLSNGHIVPALLAGNTVLYKPSEHTPAVAELIIQCWHDSGLPPGVINCLQGNANCGNTLLSQDIQGVYFTGSYATGLRIHQQFCNRPEVILALEMGGNNPLVIDEVKDIDAAVYHTILSTMITAGQRCTCARRIIIPDSQTGDLFLERFAKACKLMRIGSFDSQPEPFIGPVISHVQALKHLHAQKQLIEMGGEIILPMSLLLEYTGLVSPGIIDMTRAKNPPDEEIFAPFAQIYRYNHFDEAIQLANQTRYGLSAGLLSDNKDHYQQFYQNIRAGLINWNRPTTGAASSLPFGGVGCSGNHRPSAYFAADYCAYPVASMEQPLLTTPVQRLPGLVLE
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: GSPE_VIBCH
Sequence: MTEMVISPAERQSIRRLPFSFANRFKLVLDWNEDFSQASIYYLAPLSMEALVETKRVVKHAFQLIELSQAEFESKLTQVYQRDSSEARQLMEDIGADSDDFFSLAEELPQNEDLLESEDDAPIIKLINAMLGEAIKEGASDIHIETFEKTLSIRFRVDGVLREVLAPSRKLSSLLVSRVKVMAKLDIAEKRVPQDGRISLRIGGRAVDVRVSTMPSSHGERVVMRLLDKNATRLDLHSLGMTAHNHDNFRRLIKRPHGIILVTGPTGSGKSTTLYAGLQELNSSERNILTVEDPIEFDIDGIGQTQVNPRVDMTFARGLRAILRQDPDVVMVGEIRDLETAQIAVQASLTGHLVMSTLHTNTAVGAVTRLRDMGIEPFLISSSLLGVLAQRLVRTLCPDCKEPYEADKEQRKLFDSKKKEPLILYRATGCPKCNHKGYRGRTGIHELLLVDDALQELIHSEAGEQAMEKHIRATTPSIRDDGLDKVRQGITSLEEVMRVTKES
What is the function of this protein?
ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.  Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
What are the official names of this protein?
Type II secretion system ATPase E, T2SS protein E, Cholera toxin secretion protein EpsE, General secretion pathway protein E, Type II traffic warden ATPase.
What is the protein family that this protein belongs to?
Belongs to the GSP E family.
What are the subcellular locations of this protein?
Cell inner membrane. Note=Membrane association is not an intrinsic property but requires the EpsL/GspL gene product.
Protein: STE11_YEAST
Sequence: MEQTQTAEGTDLLIGDEKTNDLPFVQLFLEEIGCTQYLDSFIQCNLVTEEEIKYLDKDILIALGVNKIGDRLKILRKSKSFQRDKRIEQVNRLKNLMEKVSSLSTATLSMNSELIPEKHCVIFILNDGSAKKVNVNGCFNADSIKKRLIRRLPHELLATNSNGEVTKMVQDYDVFVLDYTKNVLHLLYDVELVTICHANDRVEKNRLIFVSKDQTPSDKAISTSKKLYLRTLSALSQVGPSSSNLLAQNKGISHNNAEGKLRIDNTEKDRIRQIFNQRPPSEFISTNLAGYFPHTDMKRLQKTMRESFRHSARLSIAQRRPLSAESNNIGDILLKHSNAVDMALLQGLDQTRLSSKLDTTKIPKLAHKRPEDNDAISNQLELLSVESGEEEDHDFFGEDSDIVSLPTKIATPKNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYRPSALELLQHPWLDAHII
What is the function of this protein?
Serine/threonine protein kinase required for cell-type-specific transcription and signal transduction in yeast.  It is thought that it phosphorylates the STE7 protein kinase which itself, phosphorylates the FUS3 and or KSS1 kinases.
What are the official names of this protein?
Serine/threonine-protein kinase STE11.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Protein: MPCP1_ARATH
Sequence: MTRVKSKLDEELSSPWFYTVCTMGGMLSAGTTHLAITPLDVLKVNMQVNPVKYNSIPSGFSTLLREHGHSYLWRGWSGKLLGYGVQGGCRFGLYEYFKTLYSDVLPNHNRTSIYFLSSASAQIFADMALCPFEAIKVRVQTQPMFAKGLLDGFPRVYRSEGLAGFHRGLFPLWCRNLPFSMVMFSTFEQSVEFIYQKIIQKRKQDCSKAQQLGVTCLAGYTAGAVGTIISNPADVVLSSLYNNKAKNVLQAVRNIGFVGLFTRSLPVRITIVGPVITLQWFFYDAIKVLSGFPTSGGVKKPVDAAKLSV
What is the function of this protein?
Transport of phosphate groups from the cytosol to the mitochondrial matrix.  Mediates salt stress tolerance through an ATP-dependent pathway and via modulation of the gibberellin metabolism.
What are the official names of this protein?
Mitochondrial phosphate carrier protein 1, mitochondrial, Mitochondrial phosphate transporter 1, MPT1, Phosphate transporter 3;3.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ACOT8_RAT
Sequence: MSKPEDLGDANGDADRGDLSGDLRSVLVTSVLNLEPLDEDLYRGRHYWVPTSQRLFGGQIVGQALVAAAKSVSEDVHVHSLHCYFVRAGDPKVPVLYHVERTRTGASFSVRAVKAVQHGKAIFICQASFQQMQPSPLQHQFSMPTVPPPEELLDHEALIDQYLRDPNLHEKYRVGLNRIAAREVPIEIKLVNPPALNQLQTLEPKQMFWVRARGYIGEGDIKMHCCVAAYISDYAFLGTALLPHQSKYKVNFMVSLDHSMWFHAPFRADHWMLYECESPWAGGSRGLVHGRLWRRDGVLAVTCAQEGVIRSKPRVSESKL
What is the function of this protein?
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:11785945).  Displays no strong substrate specificity with respect to the carboxylic acid moiety of Acyl-CoAs (By similarity).  Hydrolyzes medium length (C2 to C20) straight-chain, saturated and unsaturated acyl-CoAS but is inactive towards substrates with longer aliphatic chains (PubMed:11785945).  Moreover, it catalyzes the hydrolysis of CoA esters of bile acids, such as choloyl-CoA and chenodeoxycholoyl-CoA and competes with bile acid CoA:amino acid N-acyltransferase (BAAT) (By similarity).  Is also able to hydrolyze CoA esters of dicarboxylic acids (By similarity).  It is involved in the metabolic regulation of peroxisome proliferation (By similarity).
What are the official names of this protein?
Acyl-coenzyme A thioesterase 8, Acyl-CoA thioesterase 8, Choloyl-coenzyme A thioesterase, Peroxisomal acyl-coenzyme A thioester hydrolase 1, PTE-1, Peroxisomal long-chain acyl-CoA thioesterase 1.
What is the protein family that this protein belongs to?
Belongs to the C/M/P thioester hydrolase family.
What are the subcellular locations of this protein?
Peroxisome matrix. Note=Predominantly localized in the peroxisome but a localization to the cytosol cannot be excluded.
Protein: SCS3_YEAST
Sequence: MSSKWFNAIHLLVCPLTVLVGYLMNAYGYGAALQATLNKDGLVNAMLVKKGWFWTSLVGWWCIIRYRAVPGATGRDRRHIVQSFKRYAILTVWWYVFTQGIWFGVGPIMDLVFVYTGGHCHYDVFDDAGHVNEDFQGSVTRTNRALALIHNVLTLHGHHQEHRQQQLWDRSIGSIQGALQATQPKTPKNVTASAAAAINTFIHDQMHRWQGPLTTSAQCRRFGGHWAGGHDPSGHVFLATLMCMFLLGELRVFGRRALAHLYAQKWQLVRLVTRLFDTGPLWTWRRCGGGSMTCGARLWRAIVEPPVTCAAALLRLTRCIACDHPVIILLTLLVTWLWQLLLTAVASRFHTVREHMSGLLAAYIVTGLVYARDAAALRPV
What is the function of this protein?
Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate.  Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen (By similarity).  This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis (PubMed:26504167, PubMed:29526591, PubMed:32915949) (By similarity).  May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis (By similarity).  May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation (PubMed:29526591) (By similarity).  May play a role in the regulation of cell morphology and cytoskeletal organization (By similarity).  Involved in phospholipid biosynthesis (PubMed:7706223, PubMed:29417057, PubMed:32915949) (By similarity).
What are the official names of this protein?
Acyl-coenzyme A diphosphatase SCS3, FIT family protein SCS3.
What is the protein family that this protein belongs to?
Belongs to the FIT family. Fungal FIT2B/SCS3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched at sites of lipid droplet (LD) biogenesis.
Protein: RPAL2_PELHO
Sequence: MSNPNNGAEWQQVEADQLDSGLYYGRFALSPLTAKQASLLKKGLPEALLTEILCLRFTHAKIQNECVNLMNIVGIQESLDEILKNFGKIILTGKLEEFVGKGPFVAILDVRGPLNAMAVDIELPPGIKVEIETQHIATITEPIPFVVELKIELVSSTSKGETGITDEEGFSIDPNPPIQKVDTSIQCYDYQGEPFQTLFLDIWTDRTIHPHEALAQASRKIFGLLSLVFQAEYFQYNELENGLRYGKFCLYPMTKEQFQWIQTALNEALALDMSGESKHEGPVTDEEGDSIDPTFTPVQKWDITMNSYQYSGETFQGLLSRF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
Putative DNA-directed RNA polymerase subunit alpha-like 2, Putative PEP 2, Putative plastid-encoded RNA polymerase subunit alpha 2, Putative RNA polymerase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLAA_PETGR
Sequence: MGTATAQPALRPQTSTVIGGLHGAAVLDNTGRTVIDVTDFGADPSGKADSAAAVSAAMAHAKTVGGPTTLHFPTGTYHIWPERTPKRELYVSNTVGSDQAFRTKNIGILVEDMRDVVVDGGGSRIVNHGFQTVFAAIRSSDVRFTNFSQTWVAPKTVDITVADAGVVSGQAYRIIDIPETYDYAVEGTSVRWNGERGPATGQPYWTGTNSFDYSQVHDPATNRTWRTSNPVFPERHEDHRPRRRQVRITYGDSTAPGDRGYVYQMREVTRDTPGALFWESSRVTVDHLRLGYLHGFGIVGQLSEDIGIDSVTFKADRGSGRVTSGFADHIQMSGVKGTVRITNSVFDNPQDDPINIHGTYLQATAAERETLQLRYMHNETSGFPQFYPGDTIELVDKRTMLAAPGATAKVVSVTGPTGSGVPAGTDPDTYLRTMTVVLDRTLPAAVLAAPGDYVAENTTYTPTVEITGNTFQAVPTRGILVTTRRPVRIENNRFDGMSMASIYISSDARSWYESGPVRNVTIRGNVFDRPASPVIFFDPTNQDFVAGQPVHRNVLIEDNDFNLTGGTILSGRGVGGLTFRDNRVERYPHLRLTGPSRALRVGDTTTVTTDAPPPSHTSPLFTFDGADDITLANNTYGNGFNKRVNTANMDVSEITVTADGLALNADSISSAPVAVSYSSSRPKVATVDSEGVVKALSGGTTSITARATIGGVRVTSNPVKVVVATER
What is the function of this protein?
Alpha-galactosidase that specifically removes branched alpha-1,3-linked galactose residues present in blood group B antigens.  Has no activity toward linear alpha-1,3-linked galactose residues.
What are the official names of this protein?
Alpha-1,3-galactosidase A, Exo-alpha-galactosidase A, SgGal110A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 110 family. A subfamily.
Protein: 6PGL_SYNY3
Sequence: MAPQVDVLINKQILIERALVCVTTRITKAIAERGQGTIALSGGNTPKPLYEALARQALPWEKIHVFWGDERYVSVDHPDSNQRMARLAWLDQVDIPEANIHPMPTAAADPEQDAQTYENELATFFQVEAGHFPAFDLILLGLGDDGHTASLFPHTPALTVGDRLITVGNKDGQPRLTFTIPLINRARSVVFLVAGASKQHALGEIFAPEADPQQYPARFIQPQGELIWLLDQQAGENLRP
What is the function of this protein?
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6PGL.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
Protein: TIG_XANC8
Sequence: MQASIESTGNLERRLTFTLPQERLETHVGGRLRELARTTRIKGFRPGKVPTKVIEQRFGQQVRAEAMEGLLRETFDSAVREHSLRLAGNPRIDQGESDFDFVATFEVVPDFGDIDVTNLSVVRHTAEVTDADIDQMIENLRLQRRTWNPVERGAQVGDLVALETWSQAGNERLPAEGVETGSSVLGSGVMFDQIEKGLEGLSKGEDKALSIDFPADWRVPQLAGKTVQVHVKAVEVSEPVLPEVNKEFIKSFGVKSGDAEQFRADIRTNLERELKGALMNRLRREVGEQLIAAYAHVEMPPRLVENEARSMLAQQVDQMRRSGRNPGEIPADAHQGFMDAAAKRVLVGLLVGEVARRNELRLESKRVSETLRLIASTYEEPEQVIEMYRNDPQLMSGLQSRVMEEQVIDWIAERAKHTEQSLSFQDAIRV
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ATPF_PECAS
Sequence: MNINATILGQAIAFVLFVWFCMKYVWPPMMAAIEKRQKEIADGLASAERAKKDLNLAQANATDQLKKAKADAQVIIEQANKRRAQILDEAKAEAEAERNKIVAQAQAEIEAERKRAREELRKQVAVLAIAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: LBX1_RAT
Sequence: MTSKEDGKAAPGEERRRSPLDHLPPPANSNKPLTPFSIEDILNKPSVRRSYSLCGAAHLLAAADKHAPGGLPLAGRALLSQTSPLCALEELASKTFKGLEVSVLQAAEGRDGMTIFGQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEASGGGGGGGGGGCGRAKSRPGSPALPPGAPQAPGGGPLQLSPASPLTDQRASSQDCSEDEEDEEIDVDD
What is the function of this protein?
Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord.
What are the official names of this protein?
Transcription factor LBX1, Ladybird homeobox protein homolog 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: GREA_MYCGE
Sequence: MELNKNYLTQEGFKQLEKELENLIQVKRPEIIRLLQEARDQGDLSENADYDAAKAQQGEIETRIAEIQDILANAKLISDHQAKTKVTKVSLGSTVEIYDYSSKSNEKYTIVGTLEANPEEHKISNESPLALAIYGRLIGDECDVVGIEVPYRVKILKISNR
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: ACCD_LACLM
Sequence: MALFQKKKYIKINPNRSIIEKQAEQPEVPDELFAKCPACKHTIYQKDLGKNKVCPNCDYNFRITAKERLAIVADKDSFIEMFTGIESKNPLDFPGYPEKLAATKARTGLDEAVMTGTATIKGQKTALAIMDSTFIMASMGTVVGEKLTRLFEYATTEKLPIIVFTASGGARMQEGIMSLMQMAKTSAAVKRHSNAGLFYITVLTDPTTGGVTASFASLGDIILAEPQSLIGFAGRRVIEQTVRQTLPDDFQKAEFLLNHGFVDAIVKRTELRQKLALLLELHTEVENV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_ISAV8
Sequence: MADKGMTYSFDVRDNTLVVRRSTATKSGIKISYREDRGTSLLQKAFAGTEDEFWVELDQDVYVDKKIREFLVEEKMKDMSTRVSGAVAAAIERSVEFDNFSKEAAANIEMAGVDDEEAGGSGLVDNRRKNKGVSNMAYNLSLFIGMVFPALTTFFSAILSEGEMSIWQNGQAIMRILALADEDGKRQTRTGGQRVDMADVTKLNVVTANGKVKQVEVNLNDLKAAFRQSRPKRSDYRKGQGSKATESSISNQCMALIMKSVLSADQLFAPGVKMMRTNGFNASYTTLAEGANIPSKYLRHMRNCGGVALDLMGMKRIKNSPEGAKSKIFSIIQKKVRGRCRTEEQRLLTSALKISDGENKFQRIMDTLCTSFLIDPPRTTKCFIPPISSLMMYIQEGNSVLAMDFMKNGEDACKICREAKLKVGVNSTFTMSVARTCVAVSMVATAFCSADIIENAVPGSERYRSNIKANTTKPKKDSTYTIQGLRLSNVRYEARPETSQSNTDRSWQVNVTDSFGGLAVFNQGAIREMLGDGTSETTSVNVRALVKRILKSASERSARAVKTFMVGEQGKSAIVISGVGLFSIDFEGVEEAERITDMTPEIEFDEDDEEEEDIDI
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases (Probable).  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication (PubMed:15522447).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N, vp66.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host nucleus, host nucleolus.
Protein: RBL_CALHE
Sequence: DILAAFRVSPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYQIEPVPGEPDQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIIMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDYIEKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAVEGNTIIREACKWSPELAAACEVWKEIKFEFAAMDTLDK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.