PharMolix/UniProtQA huggingface dataset:
Protein: FLIV_SALMU
Sequence: MNIAPDSKVKTSLVLQMQNYFRSLPLNRGSVILDHYIQCLLRVLTAEEGVSMEQKVSDIESSLARCLQADEQQKNWAFRNLILYKIWENNLGNQPNVDPLRALYIIVAEYAFIKLLTAASVHERGRLEWDDVTNIVYSFHSRSQHNSEVAKNFHRHIETVRTGDDLSMIHLLT
What is the function of this protein?
Required for the secretion of flagellin and expression of motility.
What are the official names of this protein?
Flagellar biosynthetic protein FliV.
What is the protein family that this protein belongs to?
Belongs to the FliB family.
Protein: TRMD_ANAD2
Sequence: MARLEVDILTLFPRMCAGYLGESILGKAQEAGLLAATITDIRDHATGKHRVCDDAPYGGGAGMVMKPEPLVEAIEAARARLPGAWVVLTSPRGARLDQALARRFAEHGRLILACGRYEGVDERVMTAVDMQVSIGDFVLTGGELAALCVVDAAARLVPGVLGNAASADAESFAGVEGLLEHPQYTRPPEFRGMKVPEVLLSGDHRRIERWRRREALRATRERRPDLFARLSLPESDLRLIEAGDDEL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_STRPD
Sequence: MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGPDIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVAAYQAIKAEWAG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RECA_LISW6
Sequence: MNDRQAALDQALKQIEKQFGKGSIMKLGEHSDQNISTISSGSLALDIALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQAQGGTAAFIDAEHALDPAYAKNLGVNIDELLLSQPDTGEQALEIAEALVRSGAVDMLVIDSVAALVPRAEIEGEMGDAHVGLQARLMSQALRKLSGAINKSKTIAIFINQIREKVGVMFGNPEITPGGRALKFYSTVRLEVRRAEQLKQGTDVMGNKTKIKVVKNKVAPPFRIAEVDIMYGEGISREGELVDMAAEVDVINKSGSWYSYKEERIGQGRENAKQYLKEHTDIRDEISQRVREEYEIDGANKEPLEETEETLSLLDDE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREF_ECO57
Sequence: MPTPEKRLRLMQLASNSLPVGGYSWSQGLEWAVEAGWVEDSAAFEHWQQLQMEQSFFAVDLPLLARLYRACEAGDPDSAGRWTAYLLACRETRELRDEERNRGAAFTRLLVDWQPDCPAEWRKLCQQSQLTGMAWLGVRWQISVSDLALSLGYSWIESAVMAGVRLVPYGQLAAQQLIMRLCARYAANMDSALATPDHAIGSATPLASIASARHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IAH1_MOUSE
Sequence: MSLCERAASGSALLWPRVLLFGDSITQFSFQQGGWGSLLADRLVRKCDVLNRGFSGYNTRWAKIILPRLIRKGPGMENPVAVTIFFGANDSSLKDENPKQHVPLDEYSANLRDMVQYLRSVDVPRERVILITPPPLCEAAWEKECVLKGCKLNRLNSVVGEYANACLQVARDCGTDVLDLWTLMQKDSQDFSSYLSDGLHLSPMGNEFLFLNLCPLLDKKVSSLPWLLPYWKDVEEAKPELSLLGDGDY
What is the function of this protein?
Probable lipase.
What are the official names of this protein?
Isoamyl acetate-hydrolyzing esterase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
Protein: DEND_HAEIN
Sequence: MKVVITGGQGFLGQRLAKTLLAQNNVHIDDLILIDVVKPIAPNNDPRVRCYEMNLRYPTGLDELITEETDAIFHLAAIVSSHAEQDPDLGYETNFLATRNILEICRKNNPKVRFIFSSSLAIFGGELPETILDSTAFTPQSTYGTQKAMCELLINDYSRKGFVDGIVVRLPTICIRPGKPNKAASSFVSSIMREPLHGEDAVCPVSEELRLWLSSPNTVVANFIHALQLPSLPLRSWHTINLPGFSVTVKQMLSDLTQVKGEAILEHIKFEFDESINNIVASWPSRIDNTQALALGFKVDSNFQNVIQQFIEYDM
What is the function of this protein?
Catalyzes oxidation of D-erythronate to 2-oxo-tetronate.  Can use either NAD(+) or NADP(+) as cosubstrate, with a preference for NAD(+).
What are the official names of this protein?
D-erythronate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: ARLY_NEIM0
Sequence: MHDKTWSGRFNEPVSELVKQYTASIGFDRRLAEWDIQGSLAHAQMLKETGVLDEGDLADIRRGMAEILEEIRSGKIEWSSDLEDVHMNIERRLTDKIGDAGKRLHTGRSRNDQVATDIRLWLRDQITVIQSLIQSLQTALLDLAEQNAETVMPGFTHLQVAQPVSFGHHMLAYVEMLGRDNERMADCRCRVNRMPLGAAALAGTTYPIQREITAELLGFEQICQNSLDAVSDRDFAIEFTAAASLVMVHLSRLSEELILWMSPRFGFIDIADRFCTGSSIMPQKKNPDVPELVRGKSGRVIGHLIGLITLMKSQPLAYNKDNQEDKEPLFDTADTLIDTLRIYADMMRGVTVKPDNMRAAVMQGFATATDLADYLVKKGMPFRDAHEVVAQAVRHADQAGVDLSELPLEVLQGFSDLIADDVYGVLTPEGSLNARNHLGGTAPEQVRFQVKRWREMLA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_ENTFA
Sequence: MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGPIDDNVANSVIAQLLFLDAQDSEKDIYLYINSPGGSVSAGLAIFDTMNFVKADVQTIVLGMAASMGSFLLTAGQKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILDTRQRLNSILAERTGQPIEVIERDTDRDNYMTAEQAKEYGLIDEVMENSSALN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHIC1_HUMAN
Sequence: MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD
What are the official names of this protein?
Cysteine-rich hydrophobic domain-containing protein 1, Brain X-linked protein.
What is the protein family that this protein belongs to?
Belongs to the CHIC family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasmic vesicle. Note=Also present at a Golgi-like vesicular compartment and at scattered vesicles.
Protein: MRAZ_FRAAA
Sequence: MFLGSHTPRLDDKGRLTLPAKFRDELEGGLVITKGQERCLYVFPMAEFTRISESLRTAPVTAKALRDYSRVFFSSAADDAPDRQGRITIPAPLRTYAGLTRDCVVNGANTRVEIWDAQRWQAYLESQEESFAELSEEVLPGVI
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MURA_ACIF2
Sequence: MDKLLLRGNGPLRGELRISGAKNAALPCLAATLLAREPVRLCNIPHLRDITTTLELLSTLGARVLVDGQLGIEVDPRPVHSVVAPYELVKTMRASILVLGPLLARHGSAEVSLPGGCAIGSRPVSVHLSGLQALGAEITVEDGFVKAQAARLRGTRIVMEMVSVTGTENLLMAATLAEGRTILENAAREPEIVDLARCLSAMGARISGAGTSVIEIEGVAELHGAEHSVVPDRIETGTYLVAAAMTGGDICLKRTDAGLLESVLLKLKEAGAEVTTGADTIRIRMKRRPRAVDVRTAPFPAFPTDMQAQFMAMNCIAEGSSVVTETIFENRFMHVSELQRLGADINADGKTAVVRGVQRLRGAPVMATDLRASASLVLAGLVAEGETLIDRIYHLDRGYEVIEEKLSALGADIRRISNTRSVA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_PSEE4
Sequence: MADVKKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKAQAMGVKEIYIDDLREEFVRDFVFPMFRANTVYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDYAEKHGIPIERHGKKKSPYSMDANLLHISYEGGVLEDTWTEHEEDMWRWSVSPENAPDQATYIELTYRNGDIVAIDGVEKSPATVLADLNRIGGANGIGRLDIVENRYVGMKSRGCYETPGGTIMLKAHRAIESITLDREVAHLKDELMPKYASLIYTGYWWSPERLMLQQMIDASQVNVNGVVRLKLYKGNVTVVGRKSDDSLFDANIATFEEDGGAYNQADAAGFIKLNALRMRIAANKGRSLL
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYME_SALPA
Sequence: MTTVHSIADPCDPEVSPTNNRHLTVSYASRYPDYTRIPALTMKGQWLEAAGFATGTEVDVRVMNGCIVLTAQQPQPEESELMQSLRQVSKLSARKQKQVQAFIDVMAGSK
What is the function of this protein?
Involved in the degradation and recycling of damaged RNA.  It is itself a target for degradation by the ATP-dependent protease Lon.
What are the official names of this protein?
Endoribonuclease SymE.
What is the protein family that this protein belongs to?
Belongs to the SymE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGH_PSE14
Sequence: MNRISVPRFSVLIASLCGITLLSGCVAPTAKPNDPYYAPVLPRTPMSAAANNGAIYQAGFEQNLYGDRKAFRIGDIITITLSERMAASKAATSAMTKDSTNSIGLTSLFGSGLTTNNPIGGNDLSLNAGYNGARTTKGDGKAAQSNSLTGSVTVTVADVLPNGILAVRGEKWMTLNTGDELVRIAGLVRADDIATDNTVSSTRIADARITYSGTGAFADTSQPGWFDRFFLSPLFPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: TRPF_NEIMB
Sequence: MRKIRTKICGITTPEDAAAAAAAGADAVGLVFFQGSSRAVDIARAKKITAALPPFVSVVALFVNESAQNIRRILAEVPIHIIQFHGDEDDAFCRQFHRPYIKAIRVQTASDIRNAATRFPDAQALLFDAYHPSEYGGTGNRFDWTLLAEYSGKPWVLAGGLTPENVGEAVRITGAESVDVSGGVEASKGKKDAAKVAAFIATANRLSR
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RBPJL_MOUSE
Sequence: MDPRETTDPSLPPGPLTHLSLPDSSEVRLQSDGPSLLGSWTRSPPEHAIILREGVRTCLQQRCEQTVWILHAKVAQKSYGNEKRFFCPPPCVYLAGPGWRVKPMQDQALQSAETGPTVCGYMGLDGASGSAPETQKLNFEEQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGQELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHCSQGDFPPQEGYIRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPSDTPGGAGTYLCLATEKVVRFQASLCPKEANRALLNDSSCWTIIGTESVEFTFSTSLACTREPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFGSDWRWLRTPITVPVSLLRADALFYPSPFSFTYTPEYSALPRLPNAQEPAPDADTLLESIHHEFTRTNFHLFCPT
What is the function of this protein?
Putative transcription factor, which cooperates with EBNA2 to activate transcription.
What are the official names of this protein?
Recombining binding protein suppressor of hairless-like protein, Transcription factor RBP-L.
What is the protein family that this protein belongs to?
Belongs to the Su(H) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPD_LEPIC
Sequence: MEPRAAVLKLIEHKHLTALEAESFMNHVMKGEVSEILLSSFLTAMRFNGESVEEVLGCTLALRKNALRPKTVFPFDLLDTCGTGGDGQGTINISTLSAIVLASLGIKVAKHGNRSVSSHTGSSDILTRLGYQTETTQEEVEAHLVNRGFTFLFAPMWHPSMKHAGPVRKELGFRTVFNMIGPLSNPFSPQFQIIGVYQPELMELFIKVLQSLGLKRALVCHSRDGLDEFSIFQITDYTFLENGVISRHSFDPKILGLSSLNKEEVYASSSDHAEVLARKVLNSESIAGTHAVALNAGAGLFVMGKIDTIEQGYQIAKEAILSGKTKKYFEDLISKE
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: Y2059_PSEPK
Sequence: MKREQIEGVAEDLAGKAQSAVGRLVEDPALEAEGDARQAAGQVTKTYGDTLDTVSSFVKEKPFAALAITAAVTLVVSRLLRR
What are the official names of this protein?
UPF0337 protein PP_2059.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: SMOS1_ORYSJ
Sequence: MASPGPAAGMQQKLEAAAAAAGGGDGAEWGRGMQKMEAVGAGGEGVGAGAEQVAPPPRRPVAARKERVCTAKERISRMPPCAAGKRSSIYRGVTRHRWTGRYEAHLWDKSTWNQNQNKKGKQVYLGAYDDEEAAARAYDLAALKYWGAGTQINFPVSDYARDLEEMQMISKEDYLVSLRRKSSAFSRGLPKYRGLPRQLHNSRWDASLGHLLGNDYMSLGKDITLDGKFAGTFGLERKIDLTNYIRWWLPKKTRQSDTSKMEEVTDEIRAIESSMQRTEPYKFPSLGLHSNSKPSSVVLSACDILSQSDAFKSFSEKSTKLSEECTFSKEMDEGKTVTPVPATGHDTTAVNMNVNGLLVQRAPYTLPSVTAQMKNTWNPADPSADPLFWTNFILPASQPVTMATIATTTFAKNEVSSSDPFHGQE
What is the function of this protein?
Transcription activator involved in the control of organ size (PubMed:24486766).  Acts as an auxin-dependent regulator for cell expansion during organ size control (PubMed:24486766).  Binds to the promoter of PHI-1, a gene that regulates cell expansion, and positively regulates its expression (PubMed:24486766).  Cooperatively functions in a transactivating complex with DLT to enhance the transcription of the SMOS1 target PHI-1, and to regulate plant organ size (PubMed:28069545).  Interaction between SMOS1 and DLT is a crosstalk point for auxin and brassinosteroid (BR) signaling (PubMed:28069545).  Acts as positive regulator of BR signaling (PubMed:28100707).  Cooperatively functions in a transactivating complex with BZR1 to enhance the transcription of BR biosynthetic genes (PubMed:28100707).
What are the official names of this protein?
AP2-like ethylene-responsive transcription factor SMOS1, Protein REDUCED LEAF ANGLE 1, Protein SMALL ORGAN SIZE 1.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. AP2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes mostly in the nucleus.
Protein: LV1B_MOUSE
Sequence: MAWISLILSLLALSSGAISQAVVTQESALTTSPGETVTLTCRSSTGAVTTSNYANWVQQKPDHLFTGLIGGTNNRAPGVPARFSGSLIGNKAALTITGAQTEDEAIYFCALWYSNHWVFGGGTKLTVLG
What are the official names of this protein?
Ig lambda-1 chain V regions MOPC 104E/RPC20/J558/S104.
Protein: NFYA_DICDI
Sequence: MNQINYLTSERNFLPPTDRDILNLGNNSSNSNNNSSSSNNNNNNNNNNNNNNNNNNNNSNSNSNSNNNNNNNSNNNNSSSSPDHMSLHSNGMDIHHNQQNHHYQNIQHQPHHFQQNYDERRIDYGNNNNNNNTNSMNNSNNNSNNNSNNNSNNNNNNNNNNNNNNNNNNSNNNNNSNNNNFNYNIKQQPQQTLQNQIVNMNGNIITSNGNHHYPTPHMLYARMAEIVEEPLYVNAKQYNRILKRRAARAKLESENKLPKTRKAYQHESRHQHAIRRQRGCGGRFLTKADQAKLDAQNAANAAAAAANPNASSTSTTTSNITNNNNNNNNNNNTNNNNNNNNTNVNGSGGSGGSNKIASSDDDIENDVENDSDSANIKNNSNSPNQSSSSPPPSKSKVVKKSNTINKRNNNINNNNNNNNNNNNEKTQPISSSSSSSSPLLNNGHIQAQQNQSPSSSPSQNLPPLNFSNNINNNINNNGNPTNFNNNNPNNNPNNNNNNNPNNNSFLPPLSNFSNNRS
What is the function of this protein?
Component of the NF-Y/HAP transcription factor complex.  The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters (By similarity).
What are the official names of this protein?
Nuclear transcription factor Y subunit alpha, CAAT box DNA-binding protein subunit A, Nuclear transcription factor Y subunit A, NF-YA.
What is the protein family that this protein belongs to?
Belongs to the NFYA/HAP2 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBL13_ARATH
Sequence: MGRPLFYDIIEKPATSCIVTLCSVIWFVIQKKSIGYSQVGLSYETAIEGHYWRMITSALSHISVLHLVFNMSALWSLGVVEQLGHVGLGTAYYLHYTLVLVVFSGVLVIGIYHLLIARFKIDYFRRVTAVGYSCVVFGWMTILSVKQPSSKLNLFGLLSLPISFAPFESLIFTSIIVPQASFLGHLSGILVGYAISWGLIGGMNNYWALTMLGWIVVVFVFSLKKSGAYDFSFLEIESLTDASLPSVRFIGNGRTLQASAVPLSGVEVV
What is the function of this protein?
Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
RHOMBOID-like protein 13, AtRBL13.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NOVA2_MOUSE
Sequence: MEPEAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLSLGLNSAAASGVLAAVAAGANPAAAAAANLLASYAGDAGAGPGAGAAPPPPPPPGALGSFALAAAANGYLGAGAGGAAGAGGAPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYEQGVRASNPQKVG
What is the function of this protein?
Functions to regulate alternative splicing in neurons by binding pre-mRNA in a sequence-specific manner to activate exon inclusion or exclusion.  It binds specifically to the sequences 5'-YCAY-3' and regulates splicing in only a subset of regulated exons (PubMed:14615540).  Binding to an exonic 5'-YCAY-3' cluster changes the protein complexes assembled on pre-mRNA, blocking U1 snRNP binding and exon inclusion, whereas binding to an intronic 5'-YCAY-3' cluster enhances spliceosome assembly and exon inclusion (PubMed:16041372).  With NOVA1, they perform unique biological functions in different brain areas and cell types.  Uniquely regulates alternative splicing events of a series of axon guidance related genes during cortical development, being essential for central nervous system development by regulating neural networks wiring (PubMed:27223325, PubMed:16041372).  Regulates differentially alternative splicing on the same transcripts expressed in different neurons.  This includes functional differences in transcripts expressed in cortical and cerebellar excitatory versus inhibitory neurons where is required for, respectively, development of laminar structure and motor coordination and synapse formation.  Also the regulation the regulation of intron retention can sequester the trans-acting splicing factor PTBP2, acting as a variable cis-acting scaffolding platform for PTBP2 across various natural conditions (PubMed:30638744).
What are the official names of this protein?
RNA-binding protein Nova-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: FORD1_AQUAE
Sequence: MYYVAQVIKDECSKYNCKQCTLFCPEPNTLMYTDEGHHAYVNTLRCKGCALCVYVCSELLKRDSIEMVYAENRDVAGVR
What are the official names of this protein?
Ferredoxin oxidoreductase 1 subunit ForD, Ferredoxin oxidoreductase 1 subunit delta.
Protein: PURA_RHOPS
Sequence: MANVVVVGAQWGDEGKGKIVDWLSEQADIVARFQGGHNAGHTLVINGETYKLALLPSGVLRPSKLAVIGNGVVFDPQAFLDEVERLTKQGVAISPENLRVAENVTLILPLHRELDALRENASKATSIGTTQRGIGPAYEDKVGRRAIRLMDLADIDTLPHKIERLLTHHNALRRGLGLSEFEAGAILKELTALAPRLLPYAETVWRLLDIKRREGKRILFEGAQGALLDVDHGTYPYVTSSNTVAAQAATGTGMGPGSVGYVLGICKAYTTRVGQGPFPTELDNEIGRKIGERGREFGTNTGRPRRCGWFDAVLVRQTVRTCGIHGLALTKLDILDGFDSIEVCVGYMLDGKEIDHLPAGEGAQARVVPIYETIEGWKEPTANARSWADLPAQAVKYVRRVEELVGCPIALLSTSPEREDTILVQNPFEA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_STRA3
Sequence: MAKYEILYIIRPNIEEEAKNALVARFDSILSDNGATVVESKDWEKRRLAYEIQDFTEGLYHIVNVEAEDAVALNEFDRLSKINGDILRHMIVKVD
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: HCP_ECODH
Sequence: MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGDDFSAVITQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_PARXL
Sequence: MKTAQELRTGNVVMIGADAMVVQKAEYNKSGRNSAVVKMKFKNLLTGAGMESVYKADDKFDVVVLERKEVTYSYFADPMYVFMDADYNQFEVESEMMGDALHYLEDGMACEVVFYNDKAISVELPTTLVREIIYTEPAVKGDTSSGKVLKNAKLNTGFELQVPLFCNIGDKIEIDTRTHEYRSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_CERSK
Sequence: MSYNTFGHIFRVTTWGESHGPALGATVDGCPPGVAIEAEAIQHWLDRRKPGQNRFTTQRQEPDAVRILSGTFEGRSTGTPIQLMIENTDQRSKDYGEIARSFRPGHADIAYHWKYGLRDYRGGGRSSARETAARVAAGGVARAALAALVPGLRIEGYMVQIGPHAIDRARFDADEIERNPFWCPDPDTAALWADYLDGLRKAHDSVGAIVEVRASGVPAGLGAPIYGKLDSDLAAAMMTINAVKGVEIGEGMAAACLTGSANADEIRMGPEGPEFLTNHAGGILGGISTGQDVVVRFAVKPTSSILTPRRSVTTDGREVEVVTKGRHDPCVGIRAVPVGEAMMACVLLDHLLLDRGQTGGLRGTIG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: NUOE_BUCAI
Sequence: MQEISIKFKLTNEEINAIENQKKYYEDFRAISIEALKIVQKKRGWVSDQAIYAIAEILHINPSDVEGVATFYSQIFRKPVGRNIIRYCDSVVCFLTGYKRIQIALENYLKIKIGETTKDDRFTLLPVCCLGNCDKGPTIMINEDTYSVLTPESIPSLLESYK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit E, NADH dehydrogenase I subunit E, NDH-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the complex I 24 kDa subunit family.
Protein: HIS1_AQUAE
Sequence: MIKVALPKGRLFEETVDLLLKRGIIEKRIEEGRKLILEEGGITFFLVKPSDVPVYVESGVSDLGVCGYDVYLEKKPSVYRLMDLGIGFCRIAVAGKPESEEKYFSSTHISVATKYPNIAYEFFKKKGVKADIYYLNGSVELAPLVGLSDFILDLVQTGRTLKENGLIVIEEVGKSTAWLIANKDSFRIKNGQIMEFLSRLVQHNKDGLQVQGSS
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.