PharMolix/UniProtQA huggingface dataset:
Protein: IF2_RICB8
Sequence: MTDNQENKPKKLTLSNTKLSLNKSFDSLASTQSFVNAKSKTLVEVRKSYSGSTTTLSLNKEKGSLETGSSSGSEEFNRRLSILKKAAEQSKLNDNSQISTLSKLASINQSIASQEDPIEVEQEESSDTNKVKEEPKIEEVKDIEESTLQTPKKKEDIFVKSPLVGTRTRYGIESEKTVDKVTENKVIAPKPKVEESRKFKKTDLFNMVGDDENDNRNRTRSLASIKRAREKEKRKSLVQVPEKVYREITLPEVIGVGDFANAMSERVSDVIKELMKLGILANASQTIDADTAELVATHLGHAVKRVQESDVENILITNDKEEDLRSRAPVVTVMGHVDHGKTSLLDALKSTDVASGETGGITQHIGAYRVTLADGRAITFIDTPGHEAFSEMRSRGAGVTDIVIIVVAADDGIKPQTVEAINHAKAANVPIIVAINKIDKPDIDIERIKNELYMYEIIGEEAGGDVMVIPISALKKINLDKLEEAILLIAEMQNLKASPFGSASGVVIESKIEKGRGALTTMLVQRGTLKSGDIIIAGTAYGKVKKMTNDKGIEVLEATPSVPIEIQGLSHVPHAGDMFNVVQTEKQAKDIAEYRERVAKEKKISIAPRSSLEDLFLKASGSSKIKELPLIIKGDVHGSVEAIAGSLLKLPNDEVKLRILHSGVGPITESDVSLAHASSAIIVGFNVRAGANAKTAAEKEKVEIRYYSIIYDLLDDVKAIMSGMLDPIIREQYIGSVEIRQIFNITKIGKIAGSYVTRGIIKKGAGVRLLRDNIVIHEGKLKTLKRFKEEVKEVREGYECGIAFENYEDIREGDTVEVFELIQEKKQL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEYC_CAEEL
Sequence: MGNFSFTMFQILNLKMNLSLPYCNRSTGRICSKIRLYHRSFRSNPSLQMCFIIVFLLFIFSLIMFMKLNQNSYSGKEILGYLYETAIDQLTYNHTHAFITSAYYYRNSKSLGENAVAMIVAMSQRTFKHLENHEITIVGSRGYQNLKTKASITVETAEQMSCEYVMALIQGITLEIPQKLEIESAGTRVQIPFREPRKNSHSPVIICISPQFVAEKWQLFLMNIHVIRRYGGHMHIYITSMVEKLFNVLKIYEDMEALTIDYWIRMKLKKTSSPVADIMKNVEWRHQAGAQTDCLLQYKEVAEFIAFFDIDDILVPNFSHNYHQEFSSHFNAYPSYHSIFYGKRDVFVEKISSIEDFSFRHLFSNMKIQEETGYGKSIVNPLKYNSTWIHHSMKLPRNKMLKIMNTEIIHIKNILDSELNKDAPIHLPIIYGTETESVIREMDLKTLDFDFQTVYQNPIYREAALKMIDYNFYTPIVFNCYNESFYHPYFVEKKDFSQICPNADNCQLPQREDIKCIHSDGEYVSGPEMYPITFHYAVHPFWSNDIGCYQ
What are the official names of this protein?
Glycosyltransferase family 92 protein R07B7.12.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 92 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS20_RUEST
Sequence: MANSPQAKKRARQNEKRFAINKARRSRIRTFLRKVEEAIASGDKEAATAALRAAQPELMRGVTRGVYHKNTASRKISRLAARVKALG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PTFC_HALVD
Sequence: MANDAEDAVRSYLTSVKEDLMTGVSFMIPFVTIGGIFLALGYAVASLSNNVQDVFNSTGTAGWFLAQIGVAGLTLMVPVLGAYIAYAIADRPGLAPGFILSYIIQQGNVLQAAGDVIGLQGGSAGAGYLGAIVAGFLAGIVARWFKQRDVPEFIAPMMPVLLIPVATTAVLTPVMLFVLGVPISIANAGLTEFLSNMQGGGQAILLGGILGAMMAADMGGPINKVAYVFSVGLISEGVTAPMAAVMIAGMVPPIGLALSNFIAPQKYAAEMYENAKSGVLLGFSFITEGAIPYAAADPARVIPSVVAGSAVAGAASMALGVNMPAPHGGIFVVPLSNQPFMFIACILLGSIVTAVIATAIKPNFDAKMAAQSSDD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II PtfABC PTS system is involved in fructose transport.
What are the official names of this protein?
PTS system fructose-specific EIIC component, EIIC-Fru, Fructose permease IIC.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FOXN3_MOUSE
Sequence: MGPVMPASKKAESSGISVSSGLSQRYRGSGFSKALQEDDDLDFPLPDIRLEEGAMEDEELTNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPPPTPQAYQSTSGPPIWPGSTFFKRNGALLQVSPGVIQNGARVLSRGLFPGVRPLPITPIGMTAAIRNSITSCRMRTESEPPCGSPVVSGDPKEDHNYSSAKSSTARSTSPTSDSISSSSSSADDHYEFATKGSQEGSEGSFQSHESHSEPEEEDRKPSPKEGKDALGDSGYASQHKKRQHFAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKETAKN
What is the function of this protein?
Acts as a transcriptional repressor.  May be involved in DNA damage-inducible cell cycle arrests (checkpoints) (By similarity).
What are the official names of this protein?
Forkhead box protein N3, Checkpoint suppressor 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOB_RHIWR
Sequence: MATQAVPATAKKRIRKVFGNIHEVVQMPNLIEVQRESYEQFLRSRPADGYVSGLEKTLRSVFPIRDFAGTAELDFVQYELEDPKYDTDECRQRGMTYAAPMRVTLRLIVFEVDPDTETRSVLDIKEQDVYMGDMPLMTENGTFLINGTERVIVSQMHRSPGVLFDHDRGKTHASGKYLFAARVIPYRGSWLDFEFDAKDIVNVRIDRKRKLPVTSLLRALGDAVIEVNPDKGKFEAGDIVAISGVNRACRVKAVAGRLVTVEDPTGAIIPGGLIQTAEGEKIGHVARIRLQGMSGEDILNYFYRTQRFVRGENGWKVPFVAENWRGQKPAFDVVNADTGEVVFPAGTKISPRAANKAGKDGLETLLIPTDQIFGRYSAYDLIDESTGRIYIEAGDEVTPENLEALDKAGFDHVDLLDIDHVSTGPWIRNTLKADKVEDRDHALSEIYRVMRPGEPPTKETAEALFAGLFFDSERYDLSAVGRVKLNMRLELDAEDTVTTLRSEDILAVVKTLVDLKDGKGEIDDIDNLGNRRVRSVGELLENQYRVGLLRMERAVKERMSSVDVSTAMPNDLINAKPAVAAVREFFGSSQLSQFMDQTNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLASFSRVNKYGFIETPYRKIVDGKVTNEVVYLSAMEEAKHTIAQANAELDSEGRFVEDLISAREAGEFLMAPRDHVTLMDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLVRAEAPFVGTGMEETVARDSGAAIAAKRSGIVDQVDATRIVVRATGAVDAGKSGVDIYTLMKFQRSNQSTCINQRPLVKVGDVVNAGDIIADGPSTEFGELALGRNVLVAFMPWNGYNYEDSILISERIVKDDVFTSIHIDEFEVMARDTKLGPEDITRDIPNVGEEALRNLDEAGIVYIGAEVEPGDILCGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRLPPGVSGTVVDVRVFNRHGIDKDERAMAIEREEIDRLTKDREDERAILNRANYARLKEMLLGQIATAAPKGIKKGSEINEELLAEVEKREWWKFAVQDDARQADLEAVKAQYDDAVGLIVKKFEDRVEKLQRGDELPPGVLKMVKVFVAVKRKLQPGDKMAGRHGNKGVISRILPQEDMPFLEDGTPVDIVLNPLGVPSRMNVGQIFETHLGWAARGLGKQVTSALEAWREANPDAQAATPPAAVVDRLKEVYGKEYHADIEGRSTDQIVEMAGLLKNGVPMATPVFDGAREADVAEMLRRAGLDESGQVELFDGRTGDQFDRKVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALQAYGAAYTLQEMLTVKSDDVVGRTKVYEAIVKGDDTFEAGIPESFNVLVKEMRSLGLNVELSSIEDQSDDDDGLAEAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ASB15_BOVIN
Sequence: MDANDDPDEDHLTSYDVQLSIQESIEAGKTVFYPERFVPLSDQNRKLVEAIQQGHILELQEYVKYKYALDEADEKGWFPLHEAVVQPIQQILEVVLDASYKTLWEFKTSDGETPLTLAVKAGLVENVRTLLEKGVWPNTKNDKGETPLLLAIKRGSYDMVSALLKHNTSLDQPCVKRWSAMHEAAKQGHKDIIALLLNNGGNVHLKDGFGVTPLGVAAEYGHCDVLEHLIHKGGDVLALADDGASVLFEAAGGGNPDCISLLLEYGGSGNIPNRAGHLPIHRAAYEGHYLALKYLIPVTSKHAIQKSGLTPIHSAADGQNAQCLELLIENGFDVNSLLADHISESYDDERKTALYFAVCNNDILCTEILLAAGADPNLDPLNCLLVAVRANNHEIVRLLLAHGANVNCYFMHVNDTRFPSAIQYALNDEVMLRLLLNNGYQVEMCFECMHGDIFGNSFVWSEIEEEVLPGWTSCVIKDNPFCEFITVPWMKHLVGSVIRVLIDYMDYIPLCAKLKSALEVQREWPEIRQILENPCSLKHLCRLKIRRLMGLQRLCQPTLMEKLSLPPTIQRYILFKEYDLYGQELNLP
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 15, ASB-15.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
Protein: ADE_AGRVS
Sequence: MTASLLKAELHCHIEGAAPPALVAAQAEKYGIDASSFIRNGSYVWEDFTSFIAAYDFVASVFRTEEDFAALAEAYLIELAGVNTIYSELFVSPDHGEAVGLSAEAYIEGLAEGIVAARIKTGIECRMVIIGERHLGPENVLRRAKWLADYHHPLITGFNMAGEERMNRVADYAPAFDIAREAGYGITIHAGELCGAFSVRDALDLVRPSRIGHGVRAIEDADLVQRLADEGVVLEVCPASNIALKVFEDYASHPMRDLTDAGVRVCINSDDPPFFATSLANDYAIAASMGFSDVEIDAMTRTAIEAAFVDEATRQNLLQRLQAAGSGDEAAI
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: HSLO_STAAW
Sequence: MTHDYIVKALAFDGEIRAYAALTTETVQEAQTRHYTWPTASAAMGRTMTATAMMGAMLKGDQKLTVTVDGQGPIGRIIADANAKGEVRAYVDHPQTHFPLNEQGKLDVRRAVGTNGSIMVVKDVGMKDYFSGASPIVSGELGEDFTYYYATSEQTPSSVGLGVLVNPDNTIKAAGGFIIQVMPGAKDETISKLEKAISEMTPVSKLIEQGLTPEGLLNEILGEDHVQILEKMPVQFECNCSHEKFLNAIKGLGEAEIQNMIKEDHGAEAVCHFCGNKYKYTEEELNVLLESLA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_LEPBP
Sequence: MKEQKLTTENYKGTRDFYPEDMRLRNYLFSVMKDVVRSYGYEEYDGPMVESLDLYRAKTGEEIVGKQIYNFIDKGDREVAIRPEMTPTVARMVAKKLRELPRPIRWFSIPNLWRYEQPGHGRLREHWQLNVDMFGVTSSRAELEILSLACDILFAFGAPKNSFKVTISHRSLLDEFLLDGLKVSPNQAHEVSKILDKKNKITQDEYVALVTKTIPNDSSAVSKIDLFLNATVNSLNQIPGIKEETLAAIKGLFEDIKTIGLSDIIHFDPSVVRGFDYYTGFIFEIFDTSPQNKRSLYGGGRYDNLIGLFSNEELTGIGFGLGDVTLQNFLTAHNLLPNFASDTTVFIPLLDDSSFAENHNFAKELRKEKISAEVSLVSQKMGKQLSYAEKKGYRWILLRGEDEIKTNTVTLKDMASRNQFTFSFSEALQKIKEELSK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_CARHZ
Sequence: MKYTPHTPDEVREMLSSLGLSSIEELFSDIPEEVKLKRPLNLPSGMSELEVKKHLANLAAKNGSADKYTVFLGAGVYDHYVPAVVNHILLRSEFYTAYTPYQAEMSQGVLQSIFEYQTMICELTGLDITNASMYDGGSALAEAALMAVSQTRRDKVLVLATVHPEYRSVVKTYTWGPEIEVVEVPYKSGTVDLEKLEELIDDKTAAVLVQHPNFFGQLEPVEEISRLIHAQKGLLVVAVDPISLGILKPPAEYGADIAVGDGQALGNGLAFGGPHLGFFAARKDLARRMPGRLVGLTTDKEGNRGFVLTLQAREQHIRREKATSNICSNQALNALAATVYLATVGKKGLKEIALQSLQKAHYAFERLIGEGYEPLFSGPFFKEFVVKVKNEEEITQKLLKHHILAGPGISRFYPELAPALMIAVTEKRTREEIDNLVEVLGGDR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: FLS2_ORYSJ
Sequence: MERNKFASKMSQHYTKTICIAVVLVAVLFSLSSAAAAGSGAAVSVQLEALLEFKNGVADDPLGVLAGWRVGKSGDGAVRGGALPRHCNWTGVACDGAGQVTSIQLPESKLRGALSPFLGNISTLQVIDLTSNAFAGGIPPQLGRLGELEQLVVSSNYFAGGIPSSLCNCSAMWALALNVNNLTGAIPSCIGDLSNLEIFEAYLNNLDGELPPSMAKLKGIMVVDLSCNQLSGSIPPEIGDLSNLQILQLYENRFSGHIPRELGRCKNLTLLNIFSNGFTGEIPGELGELTNLEVMRLYKNALTSEIPRSLRRCVSLLNLDLSMNQLAGPIPPELGELPSLQRLSLHANRLAGTVPASLTNLVNLTILELSENHLSGPLPASIGSLRNLRRLIVQNNSLSGQIPASISNCTQLANASMSFNLFSGPLPAGLGRLQSLMFLSLGQNSLAGDIPDDLFDCGQLQKLDLSENSFTGGLSRLVGQLGNLTVLQLQGNALSGEIPEEIGNMTKLISLKLGRNRFAGHVPASISNMSSLQLLDLGHNRLDGVFPAEVFELRQLTILGAGSNRFAGPIPDAVANLRSLSFLDLSSNMLNGTVPAALGRLDQLLTLDLSHNRLAGAIPGAVIASMSNVQMYLNLSNNAFTGAIPAEIGGLVMVQTIDLSNNQLSGGVPATLAGCKNLYSLDLSGNSLTGELPANLFPQLDLLTTLNISGNDLDGEIPADIAALKHIQTLDVSRNAFAGAIPPALANLTALRSLNLSSNTFEGPVPDGGVFRNLTMSSLQGNAGLCGGKLLAPCHGHAAGKKRVFSRTGLVILVVLIALSTLLLLMVATILLVSYRRYRRKRRAADIAGDSPEAAVVVPELRRFSYGQLAAATNSFDQGNVIGSSNLSTVYKGVLAGDADGGMVVAVKRLNLEQFPSKSDKCFLTELATLSRLRHKNLARVVGYAWEAGKIKALVLDYMVNGDLDGAIHGGAAAPPPAPSRWTVRERLRVCVSVAHGLVYLHSGYDFPVVHCDVKPSNVLLDGDWEARVSDFGTARMLGVHLPAAANAAAQSTATSSAFRGTVGYMAPEFAYMRTVSTKVDVFSFGVLAMELFTGRRPTGTIEEDGVPLTLQQLVDNAVSRGLDGVHAVLDPRMKVATEADLSTAADVLAVALSCAAFEPADRPDMGAVLSSLLKMSKLVGED
What is the function of this protein?
Constitutes the pattern-recognition receptor (PPR) that determines the specific perception of flagellin (flg22), a potent elicitor of the defense response to pathogen-associated molecular patterns (PAMPs).  Recognizes flg22 from Pseudomonas aeruginosa and Acidovorax avenae.  flg22 is a peptide derived from the bacterial flagellin N-terminus sequence (PubMed:18986259, PubMed:25617720).  Does not recognize flg22 from Xanthomonas oryzae pv.  oryzae (Xoo) or Xanthomonas oryzae pv.  oryzicola (Xoc) (PubMed:25617720).
What are the official names of this protein?
LRR receptor-like serine/threonine-protein kinase FLS2, Protein FLAGELLIN-SENSING 2 homolog, OsFLS2, Protein FLAGELLIN-SENSITIVE 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: K1143_CHICK
Sequence: MSKRNQVSYVRPAEPAFLSRFKRQVGYREGPTVETKREQLPLADSDSENGSDNEDEQPQVVTLKKGDLTAEEAMKIKQQIKEALKSSEQDGEPESADGKIMFRKPAKRSSEKVLDFNVSSSKKMKKTKKTDREATSSQSTAKQVKNSSLLSFDDEENDD
What are the official names of this protein?
Uncharacterized protein KIAA1143 homolog.
Protein: WHIA_CLAM3
Sequence: MPLTSDVKEELSRVEVSKTTVRAAELATILRFSGGLHLISNRIAVESELDTPLLARRVRKDLAELYGVRSDISVIPASGMRRATHYLVRVMEGGETLARQTGLLDARRRPIRGLPNRLTTGSREEIAAVWRGAFLAAGTLTDPGRSAALEVTCPGNEAAMALVGAAGRLDVSAKAREVRGVHRVVIRDGDAIGQMLRVMGAQGTVVNWEEMRQRREVRATANRLVNFDDANLRRSAQAAVAACARVERAMEILGPDIPEHLKYAGDLRLRFRDSSLDELGHHADPPMTKDAVAGRIRRLLAMADKKAVDEGLPGTDANLPADLDDV
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: RLME_CUPPJ
Sequence: MAKGKSKNKFNQSWLHDHINDPYVKMAQREGYRARAAYKLKEIDEQDKLIQPGQVIVDLGAAPGSWSQYARNKLAASPRATGGKPDGAVVAIDILPMEPVADVTFIQGDFREEDVFRQLEEVVMAASGGAKIDLVLSDMAPNLSGVASADSARIEYLCDLALDFAQTHLKPDGALLVKCFHGSGYSQIVEKFKRQFKVVAPRKPKASRDKSSETFILGRYLKVVN
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHKL_DICDI
Sequence: MEGSKRDIIENSNNGNNKGVVIEELGETYYTNSKPSTSADCKYFRDSFEFGSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEKSNNETEKTLESNGDTTTTTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNSSNDIYMNSPSSTLSSPGNAGNNLPIGCTKPNVPKSPYSPSPPHLYKSNSTSYLKSSFFSGNGSSSSSSSTTTTNINSNNSNTNTYSTSTNVKKNNSNTNSNTNNNTNGNTNTNSNSNKKNINSNSSDNIIINDTADIMNRRRDRFKSFSWTIGESNSNSKFSELSMISSKCKSIKSEFTPLFETLTVFDESDKIRHSLIQNHYKTLLIQNPASPNRTLLTNLLQRRGHNLTTCPIDINHVLQLLQKESFSLFIFDPNESIINNTSNSISSNEPISLSSSSSYYNNNNSNNNSVNNNNNNNSGNSTNNNSPSSHTPNSPMIFQPIVSNICSNSGGSGNNSPHHIDNNNNSNQQQQQQQQQQQQQQQHQHQQQQQQSSSTTATTNNSCTLNQQQQQQQQQQQQQQQQQQQQQQSQPTTPTQSTQSPTTSISFSKKKNLTINTSFKTSPMSSPKSFNKPSQSPQNIFNNFSNTYNPNNIEFCKILKSKLTEFETVIVLTESTDPSEFCQYIDAGATDYIPQPISPILLDLRLTTCQKLVNNNLHLKKAESLKDATRKMVTCIENSPDCVEIWDPSGHIQYLNLAFSEMTGFARWELLGKEFSNLIDNTEIIPNMWATLTDKKTWNGFIRTRHNNNTLIYFEASISPVLDQFQQILYYNCTKRDVTQKRIDEESKTLEQNKIIEKSRLRLSMMSHDIRTPMSNIIGMADLLLDTSLSQHQHHYLEIIKNSSNTLLTIINDILDISKIEAGKLDIDYESFDFNATVSQVVESMAQRVQSKGLELLSYVDPKIPNILIGPSSRLNQILTNLLGNSLKFTDKGEISICCLLNDETDSEYEIKVDVRDTGIGIKKEALPLLFKAFTQAEGTITRQYGGSGLGLAICKELVHLAFNGEISVESQYGHGSTFTCILKFKKFLPSDSQNLLPASSPLQQQQQQQQHQQQTQFHQHQQQTQFHQHQQQQLQHQQHQQHQQLQQQQQQQQQLQQQLQQHQQHQLQQRQHHQQQLQQQQHHHHQQVHLQQQQQHEHDAQHNQHIQQQQQQQQQQQQQQQQHEHNNNGHHNSHGHNHHGSHHNHNHQHNNNNNNITINKLQHQEKKQKSNEQQLESITENSFSPIVEPMVISDPDTPEALNISQSPSPQSIHNGTTINQQPTSPLNTLGSKFDFSGAKMLFIERNDTSRGNLFKQLLAWNIQLELVEDGESGFRKWKQSIESNSPYSIIIMDLNTPGVDGASLPMRIKKELELMQQHLQQQQEQEQQQQQEQQQSELQKQPDVENKNSSQNNDNNNNNNKSNSSGGNQCIYRSPIIMLMPIQFLNSQLEDNLKDAGVCAILSKPIRMSQLADVFMMYLGPNSEHNNNNNYNNNNGNGYLNGGGGGGGSVNGTGNGTLQVGMSNDGGNGCGVVSFWNKQRRASAEEQEQDPSKLLGKVLVVDDNHINIQILSKMLQTVGCEVDSVLSGADALAKINQSSGDSYDAIFLDIQMPDMDGFQVSRKIREREKKFSLPRVAIIATTANVFKEDQLKCFDAGMDDFISKPIKRAEIKEIIKKYGKNGNHQSGSAYSLYKLS
What is the function of this protein?
Acts as a receptor histidine kinase for a signal transduction pathway.  This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity).
What are the official names of this protein?
Hybrid signal transduction histidine kinase L.
Protein: MGLB_ECOLI
Sequence: MNKKVLTLSAVMASMLFGAAAHAADTRIGVTIYKYDDNFMSVVRKAIEQDAKAAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVKALAINLVDPAAAGTVIEKARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGIIQGDLIAKHWAANQGWDLNKDGQIQFVLLKGEPGHPDAEARTTYVIKELNDKGIKTEQLQLDTAMWDTAQAKDKMDAWLSGPNANKIEVVIANNDAMAMGAVEALKAHNKSSIPVFGVDALPEALALVKSGALAGTVLNDANNQAKATFDLAKNLADGKGAADGTNWKIDNKVVRVPYVGVDKDNLAEFSKK
What is the function of this protein?
Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import (Probable).  In addition, binds D-galactose and D-glucose and plays a role in the chemotaxis towards these two sugars by interacting with the Trg chemoreceptor (PubMed:3057628, PubMed:4927373).  Chemotaxis requires MglB, but not MglA or MglC (PubMed:6294056).
What are the official names of this protein?
D-galactose/methyl-galactoside binding periplasmic protein MglB, D-galactose-binding periplasmic protein, GBP, D-galactose/D-glucose-binding protein, GGBP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
Protein: FLIW_DESHY
Sequence: MKIESTRFGTLDVAPEQIIHFPHGIPGFLGEKAFVHLPHDENSPFSFLQSTAEADLSFLLIDPFSFIPEYEFVLSDEMAGELELSEENPPQVFLIGTVREKITDMTVNLLAPIVVNRNKSIGRQIILDKTEYSIRHKLFSEAKASETPEGGK
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFF1_CHAGB
Sequence: MVKNPFSFRSAPVTFWTTVTYLALLIPIIIINEGTPPAPSEESPIRGTNLTQAWLDLSTLTRGYHPYNSHYNDDLRGSGSDNSEAAVTVFDDLSSNCTFLMSSGVAPAPNTPQVAAYFEGTNILVYIRGKSDDQGRWWDTAAVHDSKQNEKGLTLYFTRSENQPERGIVVMLNNGEEDYLYGARALGQHPLNPYIHTFLNLEGAGAGGRAILFRTTDREVTAAYAGSPDPFGTVIGSDAFGLGFIRSGTDYSVLYDVFGQRGLDLAFFKPRARYHTDQDDARHASKGSLWHMLSASIHTATRLSSDTGDTFIGPRSDGASGKVHNGSPSDGVWFDLFGKGFVLFGLRGMFAWSLTVLIATPLILMLLSYLLHRADKYYLFSSSVKPGDQPDDEALPVGGWKGFFRFPFALVVAGSLTIGAAFLMRKVNPFIIYSSRYSVLAMMVSLFYFSFWAIMRGANFARPSALHRVYVQIWLFILGWAMLVAVTVAEDRLRIGAEYMFVFLESSVFLSLFIALCELFALPKKNAWAQKMRDEQEERDFHRGRLHSPLSSSQIPPPVPNQESTPPGTRHSNHTASTPTIRNEDEDDDAAPTERTPLVGGNADPTRTTFATTYRRSISALVTRARRYSDSDGAGLHHDPFEREQAWSGRLPSWTWFLQFLLLGPFTITLAAQTALMLVDAVHQTGADGSSLLMPYLIAALGVVLLLLPLAPFVHRVSHHVPVFLAAVFAATLVYNLVAFPFSAAARYKVYFVQAVDLETDANRVCYHGVEEYVRAVVDSLPSASGRDVDCAGGSKKAGLVSCCFDGVATPPRLTAGASGGSGKHEEEGYGHLVAVNASRTGEHAARIEIVANNTKACFLEFEKPVSGLSVHGSSGWDERFGQYPDAGVKNVRLWHRRWDEKWVADVQWKDAEGEAASSSSSSSSFSDGDWEVLGDEDLRKRAEGLKGTVVCMWSDANVPGTIPALDEALRFVPAWVAVTKLSEGLVEGRRRFEV
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: SYI_RICPU
Sequence: MTNTKYYPEVSSNADFAGLEREILKFWQDNNIFQKSIDDRNGESEFIFYDGPPFANGLPHYGHLLTGFIKDVYARYQTVKGKKVERRFGWDCHGLPAEMQSEKELGISGRLAIANFGIEKFNAHCRASVMKYANDWEEYVTRQARWVDFKNSYKTMDKNFMESVLWAFKELYNKGLLYESMRVMPYSWACETPLSNFETRLDNSYRERADKAVTVSFVLSHPVATTTGSFKEYRILAWTTTPWTLPSNLALAVGSDIDYALVPKNDVCYIIAAYSVSKYAKELGLSGEENFEIIKGSELQGLHYKSLFDYFENHPNSFKIFAGDFVVEGDGTGVVHMAPGFGEDDQILCESKGIELVCPVDNSGKFTKEIPNLEGLQVFDANDKIIIKLKEQGNWLKTEQYIHNYPHCWRTDTPLIYKAVPSWYVKVTQFKDRMVELNQQINWIPFHVKDNLFGKWLENARDWSISRNRFWGTPLPVWKSDDPKYPRIDVYGSIEELEKDFGVKVTDLHRPFIDELTRPNPDDPTGKSTMRRIEDVFDCWFESGSMPYGQAHYPFENKEWFEDHFPADFIVEYSAQTRGWFYTLMVLSTALFDRPPFLNCICHGVILDSTGQKLSKRLNNYADPLELFDKYGSDALRVTMLSSNVVKGQELLIDKDGKMVFDTLRLFIKPIWNAYHFFTMYANADSLKGKLNFSSKNVLDVYILSKLKIAVQKIEESLDNFDTQTAYHAVSEFFEVLNNWYIRRSRARFWKSEKDTDKQNAYNTLYSCLDTMAIAMSALVPMISEAIYKGLRHCEERNDTALSGKSNVIARQDTSLDKAISGVSHKIATALSVPRNDAISVHLCNYPTLSDFEINHELVATMDNVLDICSNSLFIRSTENIRVRQPLASIAIISKHNNNLKDFEDLIKDEINVKAVIYRDDLENYTSKKLSINFPMLGKRLPHKMKEIIVASKKGEWEAITGGLAICGETLNSDEYKLVLEPYSHIKGAASFENNSSLLILDLELTPELIEEGYARDIVRFIQQARKDADFSITDRILIEIISEFNLSKIIDNYGDFIKEQTLGEFAKNFTPDYVSKVELENYQIQLKVKKS
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COMD6_HUMAN
Sequence: MEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQNFYRQFKEIAAVIETV
What is the function of this protein?
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237).  Down-regulates activation of NF-kappa-B.  Inhibits TNF-induced NFKB1 activation.
What are the official names of this protein?
COMM domain-containing protein 6.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GL1AD_HUMAN
Sequence: MATPARAPESPPSADPALVAGPAEEAECPPPRQPQPAQNVLAAPRLRAPSSRGLGAAEFGGAAGNVEAPGETFAQRVSWGPAESPPGSFSSSSLGAPLPSRTLFPSLEGDFDSVTFASVLRASGRRACCGRAVPLPGQKIHLQIARQR
What are the official names of this protein?
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5, DNA-directed RNA polymerase II subunit M, isoforms 4/5.
Protein: GLPK_STAS1
Sequence: MEKYILSIDQGTTSSRAILFDKEGKIKGIAQREFKQFFPKSGWVEHDANEIWTSVLAVMAEVLNESNVGAEQIASIGITNQRETTVVWDKHTSRPIYHAIVWQSRQTQGICQDLKEQGLEDKFRNKTGLLLDPYFAGTKVKWILDNVEGAREKADNGDLLFGTIDSWLVWKLSGGQAHITDYTNASRTLIYNIYDLEWDQELLDILEIPNTMLPEVKASSEVYAHTIDYHFFGEEVPISGIAGDQQAALFGQACFDRGDVKNTYGTGGFMLMNTGEEAVSSKSGLLTTIAYGLDGKVNYALEGSIFVSGSAIQWLRDGLRMINSAPQSENYAERVESTEGVYVVPAFVGLGTPYWDANARGAIFGLTRGTEKEHFIRATLESLCYQTRDVLEAMEKDSGIKVNNLRVDGGAVKNNFIMQFQADLLNLGVERPEINETTALGAAYLAGLAVGFWDSKDEIANRWNLEKEFQPDMIEKDRERLYKGWKKAVEATQVFKLEDE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.