PharMolix/UniProtQA huggingface dataset:
Protein: SIAT6_HUMAN
Sequence: MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI
What is the function of this protein?
Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids.  The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc.
What are the official names of this protein?
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase, Beta-galactoside alpha-2,3-sialyltransferase 3, Alpha 2,3-ST 3, Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase, N-acetyllactosaminide alpha-2,3-sialyltransferase, ST3Gal III, ST3GalIII, ST3N, Sialyltransferase 6.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single- pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
Protein: PRMA_STRP7
Sequence: METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNVDRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEVDLQARISELTDFMDLGEVKMGTTALAEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMSLFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPGMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKWDMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_SHEB5
Sequence: MPADDYPVTELTKALIARPSVTPLDEGCQTLMAERLSAIGFNIEPMVFEDTTNMWARRGNEGPVFCFAGHTDVVPTGDVSRWHTPPFVPTIIDGYLYGRGAADMKGSLAAMVIATECFVAKHPDHNGSIAFLITSDEEGPFINGTTRVIDTLEARNEKITWALVGEPSSTLKLGDVVKNGRRGSLTGNLTVKGIQGHVAYPHLADNPIHKAAPFLAELSQMHWDNGNEFFPPTSFQIANINGGTGASNVIPGALDVMFNFRYSTEVTADILIERVEALLKAHELDYDISWIFNGLPFLTGDGPLLDATRIAIRQVTGYETDPQTTGGTSDGRFIAPTGAKVLELGPVNATIHKVNECVKVDDLEQLALCYEVILEQLLC
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: SYFB_LEGPH
Sequence: MKVSKLWLREWVNFSLTEQELAEQLTMAGLEVDAVNPVAGQFTHVIVAEVLDTKPHPDADKLTLCEVNINKDKPLKIVCGAANVRPGLRVALAMIGAHLPGGLQIKESKLRGELSQGMLCSATELGLAEHSEGIMELSDEAPIGMDLREYLALDDHVFDIDLTPNRADCFSILGVAREVAVLNKLPLIEQPIVTVPPAIDDGLRVNLIHSEACPRYCGRIIRNLNLEAKTPLWMAERLRRGGIRTLHPVVDVMNYVMLELGQPMHAFDLAKINGEINVRYGVSGEQLELLDGQEVVLNDNVLVIADKEKPLAMAGIMGGANSAVQEQTQHVFLESAYFNPVTIAGVARKYGLFSDSSQRFERGVDPCLQSKALERATELILSISGGEAGPVIESFDKKFLPGTVSFLFDTTKVKKLTGLSIPLNEMKNLLEGLGVVIIKETNHFFEVTIPSHRVDLQQDADLVEEIIRLYGYDKLQAQPMQTSVQAGLISAKEKIATHVSSWFSAKGYHETISYSFVDPELQEALYPQKEFMELLNPISSELSQMRAGMWPGLIASMIYNSHRQQTAVKFFEIGVVFDLDGGQLKERSCIAGLLMGEQGNLNWSESARLFDFYDLKGDLQSLFASLKLDDVEFIQSSHHALHPGQSAQIVINGKHSGWIGVLHPRLSDAFDLDQDVVLFELNLESLINPTIPLYKPISKYPQIRRDLSFLVDRQISAMQIERVIRNTVKEDWLKSFDVFDVYMGKGIPEDKKSIAVAMTLQDDTRTLVDAEINLTISAIIKKLENEFSILLRE
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_BORPA
Sequence: MSTFPAPVLGTPLSPTATRVMLLGAGELGKEVVIALQRLGVEVIAVDRYADAPGHQVAHRAHVVSMTDPQALRQVIEQERPHVVVPEIEAIATDLLVALEDEGAVRVTPTARAAHLTMNREGIHRLAAETLGLPTSPYRFVDTEQALREAIDGGIGYPCVIKPVMSSSGKGQSIIRSADDIAAAWRYAQEGGRVGAGRVIVEGFIEFDYEITLLTVRARGADGQIVTQFCEPIGHRQVDGDYVESWQPHPMSPAALQRSREIALAVTGDLGGLGIFGVELFVAGDQVWFSEVSPRPHDTGMVTLISQVQNEFELHARALLGLPVDTRLRQPGASSVIYGGVEARGVAFEGVAQALAEPGTDIRLFGKPESFAKRRMGVGLAVADDVDQARAKAARVSQAVRVRAGA
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: ECTC_THEFY
Sequence: MIVRSLDDINGTDADVVTENWRSRRIVLARDGVGFSFHETVLYAGTETSMWYANHIELVHCIEGEAEVTNDETGETFLITPGTLYLLNGHERHTVRPKTDFRVLCVFTPPVTGREVHDENGSYPLLTEDATDTD
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: SCPA_STRMU
Sequence: MDIKLKDFEGPLDLLLHLVSKYEVDIYDVPIVDIIEQYLAYIATLQAMKLEVAGEYMVMASQLMLIKSRKLLPKVVETIEAEEDPELQLLHQIEEYRTYKLLGEELALKHNERAQRFSKPKLELIYDDITLKQDKTVLDVFLAFSKVMAEKQEEIKNSHTTIKSDDYRIEDIMTVVEEQVIRQKETNLSWFFKRAGSLNEIITIFLAALELIKVHRVYVKQEHNFDDIILRKESA
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: TACD2_RAT
Sequence: MARGLDLAPLLLLLLAMVAGFCTAQINCTCPTNKMTICNSNGPGGVCQCRAIGSQVLVDCSTLTSKCLLLKARMSARKSSRRLVNPSEHAILDNDGLYDPECDDKGRFKARQCNQTSVCWCVNSVGVRRTDKGDQSLRCDEVVRTHHILIELRHRPTDRAFNHSDLDSELRRLFKERYKLHPSFLAAVHYEEPTIQIELQQNASQKGLRDVDIADAAYYFERDIKGESLFVGRRGLDVQVRGEPLHVERTLIYYLDEKPPQFSMKRLTTGLIAVIAVVAVALVAGVVVLVVTNRRKSGKYKKVELKELGEMRSEPSL
What is the function of this protein?
May function as a growth factor receptor.
What are the official names of this protein?
Tumor-associated calcium signal transducer 2, Parturition-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the EPCAM family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NKP1_SCHPO
Sequence: MDIYEHKKSFMERQIRLLNRPMRPPKDWKLPLKSGQLSESVVETVFQRLQLRIQKHAKLNYSHQATQHVAAQIRKLYEQNSAIEDITFLNPLFYGEIDLSNLDSVKSLPHPWPFQKESRPVEKDEEQEKFNRLTGELLGLLTTLSELEQERSELEQIEKMLEPFEDGPSSIHTNMWKKNPELISTLNSTNTMVAKINSLLRGVSFPSLNNDNQEASLEDEIRSQLFEKTISDD
What is the function of this protein?
Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis.  Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly (PubMed:16079914).  Fta2, fta3 and fta4 associate with the central core (cnt) and inner repeat (inr) region of the centromere (PubMed:16079914).
What are the official names of this protein?
Inner kinetochore subunit fta4, Constitutive centromere-associated network protein fta4, Sim4 complex subunit fta4, Sim4-mal2-associated protein 4.
What is the protein family that this protein belongs to?
Belongs to the NKP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore.
Protein: PTH_RHORT
Sequence: MKLVVGLGNPGPRYAGNRHNVGFMAVAALARRHGIGPFRRKFQAQVADGQIAGARLLLLAPETFMNASGQAVGEAARFHKIAPEDIIVLHDELDLAPGKIKVKQGGGAGGHNGIRDIEAHLGPAFWRVRLGIGHPGHKDRVLTYVLGDFAKAEEDWLAPMLDAVADHFALMLEGRPADFMSKVAAQTRPAEKAKPLATAKPKEGEARTSGGSVAEVGAPPPSPTGLAAALAEALDRKSQKGNG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAX3B_XENLA
Sequence: MTSLAGAVPRMMRPCPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKVTTPEVEKKIEEFKRDNPGMFSWEIRDKLLKDGVCDRNTVPSVSSISRILRSKFGKGDEEDMELDRKEQEESEKRAKHSIDGILRERAPASPESEEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGAFPPTAMPALPTYQLSETSYQPTSIPQAVSDPSNTVHRPQPLPPSSVHQSLPSNPDSSSAYCLPSSRHGFSSYTDSFVPPSGPSNPMNPAIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPPTAVSASCSQRLEHMKSLDSLSTSQSYCPPTYSTSGYSMEPMTGYQYPQYGQSAFHYLKPDIA
What is the function of this protein?
Probable transcription factor.  Promotes both hatching gland and neural crest cell fates, two of the cell populations that arise from the neural plate border.  Acts downstream of msx1 to induce the neural crest, cooperating with zic1 and mediating signals from both the wnt and fgf8 signaling pathways.  Induction of hatching gland cell fate is independent of zic1.
What are the official names of this protein?
Paired box protein Pax-3-B, xPax3-B, Paired-domain transcription factor Pax3-B.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSLU_PECAS
Sequence: MSEMTPREIVSELDSYIIGQHKAKRAVSIALRNRWRRMQLDEALRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDSAIKMVRHQSIEKNRFRAEEMAEDRILDVLIPPAKNNWGQAEGTQEPSATRQAFRKKLREGQLDDKEIEIDLAASPVGVEIMAPPGMEEMTNQLQSMFQNLAGQKQKAHKVKIKDAFKLLIEEEAAKLVNPEELKQQAIEAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVASPSDLIPELQGRLPIRVELQALTTEDFERILTEPSASLTEQYKALMATEGVDISFTADGIRRIAEAAWQVNESTENIGARRLHTVMERLIEDVSYDASEMNGQSVIIDADYVRSHLDELVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_CORA7
Sequence: MAAIVIVGAQWGDEGKGKATDILGGKVDYVVKPNGGNNAGHTVVVGGEKYELKLLPAGILSENATPVLGNGVVINLEALFDEIDGLEARGANASRLKISANAHLVAPYHQTLDRVQERFLGKRAIGTTGRGIGPAYADKVARIGIRVQDIFDESILRQKVESALDIKNQMLVKMYNRKAIEPEQVVEYFLSYRDRLRPMVIEAELELNQALDEGKHVLMEGGQATMLDVDHGTYPFVTSSNPTAGGAAVGSGIGPTRITTSLGIIKAYTTRVGAGPFPTELFDKWGEYLQTTGGEIGVNTGRKRRCGWYDSVIARYATRVNGFTDYFLTKLDVLTGIGEIPICVAYDVDGKRYDEMPLTQSEFHHAEPIFETMPAWDEDITGCQTFEELPQKAQDYVLRLEELSGCRISYIGVGPGRDQTIVRHDVMQDQ
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAO1_ARATH
Sequence: MDSSCFLVYRIFRFRKRNKNISSSLSSSSPPSSLSQNWLHPVFLSFRGEDVRKGLLSHIQKEFQRNGITPFIDNEMKRGGSIGPELLQAIRGSKIAIILLSRNYGSSKWCLDELVEIMKCREELGQTVMTVFYDVDPSDVRKQKGDFGKVFKKTCVGRPEEMVQRWKQALTSAANILGEDSRNWENEADMIIKISKDVSDVLSFTPSKDFDEFVGIEAHTTEITSLLQLDLEEVRMIGIWGPAGIGKTTISRVLYNKLFHQFQLGAIIDNIKVRYPRPCHDEYSAKLQLQKELLSQMINQKDMVVPHLGVAQERLKDKKVLLVLDDVDGLVQLDAMAKDVQWFGLGSRIIVVTQDLKLLKAHGIKYIYKVDFPTSDEALEIFCMYAFGEKSPKVGFEQIARTVTTLAGKLPLGLRVMGSYLRRMSKQEWAKSIPRLRTSLDDDIESVLKFSYNSLAEQEKDLFLHITCFFRRERIETLEVFLAKKSVDMRQGLQILADKSLLSLNLGNIEMHNLLVQLGLDIVRKQSIHKPGKRQFLVDTEDICEVLTDDTGTRTLIGIDLELSGVIEGVINISERAFERMCNLQFLRFHHPYGDRCHDILYLPQGLSHISRKLRLLHWERYPLTCLPPKFNPEFLVKINMRDSMLEKLWDGNEPIRNLKWMDLSFCVNLKELPDFSTATNLQELRLINCLSLVELPSSIGNATNLLELDLIDCSSLVKLPSSIGNLTNLKKLFLNRCSSLVKLPSSFGNVTSLKELNLSGCSSLLEIPSSIGNIVNLKKVYADGCSSLVQLPSSIGNNTNLKELHLLNCSSLMECPSSMLNLTRLEDLNLSGCLSLVKLPSIGNVINLQSLYLSDCSSLMELPFTIENATNLDTLYLDGCSNLLELPSSIWNITNLQSLYLNGCSSLKELPSLVENAINLQSLSLMKCSSLVELPSSIWRISNLSYLDVSNCSSLLELNLVSHPVVPDSLILDAGDCESLVQRLDCFFQNPKIVLNFANCFKLNQEARDLIIQTSACRNAILPGEKVPAYFTYRATGDSLTVKLNQKYLLQSLRFKACLLLVEGQNKWPNWGMNLVTSREPDGHIVLYTPSSHLQGPLLMENLYTFEFELVVTSSEFVLEFRADRYKCALGRFDKFGVHVVWCHLDQYESKSPSCKPFWRDFPIVISNGQNILDAILKTPMPSINQ
What is the function of this protein?
TIR-NB-LRR receptor-like protein that contributes to disease resistance induced by the Pseudomonas syringae type III effector AvrB.  Acts additively with RPM1 to generate a full disease resistance response to P. syringae expressing this type III effector.
What are the official names of this protein?
Disease resistance protein TAO1, Protein TARGET OF AVRB OPERATION 1.
Protein: HBHA_MYCBO
Sequence: MAENSNIDDIKAPLLAALGAADLALATVNELITNLRERAEETRTDTRSRVEESRARLTKLQEDLPEQLTELREKFTAEELRKAAEGYLEAATSRYNELVERGEAALERLRSQQSFEEVSARAEGYVDQAVELTQEALGTVASQTRAVGERAAKLVGIELPKKAAPAKKAAPAKKAAPAKKAAAKKAPAKKAAAKKVTQK
What is the function of this protein?
Required for extrapulmonary dissemination.  Mediates adherence to epithelial cells by binding to sulfated glycoconjugates present at the surface of these cells; binds heparin, dextran sulfate, fucoidan and chondroitin sulfate.  Promotes hemagglutination of erythrocytes of certain host species.  Induces mycobacterial aggregation.
What are the official names of this protein?
Heparin-binding hemagglutinin, Adhesin.
What is the protein family that this protein belongs to?
To M.leprae HbhA.
What are the subcellular locations of this protein?
Cell surface.
Protein: GLSA_BACCN
Sequence: MQCVETNNLKQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIYHKETEYVHAGSSQMLFTLQSISKVITLALALLDRGEEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGALAITSMLKGANNEEKIERILNFVREITDNPTIHYSAKVATSELETAYLNRSLCYYMKQNGIIDNDIEELMDLYTRQCAIEVNCIDLARIGLIFAMDGYDPYKQKQIIPKHITKICKTFMVTCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGEMGIGIFGPALDENGNSIAGFKILELLSAQEGWSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: RL19_FRATO
Sequence: MKNKFVELVEKSQLRNDLPEFNPGDSITVNLWIKEGDKQRIQAFKGFVLRKRNRGLHSAFTVRKMSSGMGVERTFQTHSPLIDSIIVEKRADVRRAKLYYMRGLTGKAARIKEKV
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: HGD_BURL3
Sequence: MTLDLSKPANAGYQSGFANEFATEALPGALPHGRNSPQRAPYGLYAEQLSGTAFTAPRGHNRRSWLYRIRPAAVHRPFEPYAGPQRLVSEFGDSADVPPTPPDQLRWDPLPMPVEPTDFVDGLVTMAGNGSAAAMNGCAIHLYAANRSMQDRFFYSADGELLIVPQQGRLFIATEFGRVEVEPFEIAVIPRGVRFSVTLPDGDARGYICENFGAQLRLPDLGPIGSNGLANPRDFLTPQAAYEDREGAFELIAKLNGRLWRADIGHSPLDVVAWHGNYAPYKYDLRLFNTIGSISFDHPDPSIFLVLQSQSDTPGVDTIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGAYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASASDTTKPHKVDATMAFMFETRTLIRPTRYALDTAQLQADYFECWQGIKKHFNPEQR
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: LSPA_BACCN
Sequence: MIYYLIALFVIAIDQLSKWFIVKNMELGASIPIIDNVLYITSHRNRGAAWGILENKMWFFYIITVVFVGFIVFYMKKYAKTDKLLGISLGLILGGAIGNFIDRVFRQEVVDFIHVYIFSYNYPVFNIADSALCIGVVLIIIQTLLEGKKMKE
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLGA_DEIDV
Sequence: MRVLHVTSEVFPFSRSGGLGDVLGALPAVQATLGAQVSVLSPWYGSLAGAPEQIWAGDVADVGPVRVGELRQDGVRFLFLGLPEFEREGLYHPDDVWRFCTYGRAVLPVLRALNEVPDVLHGHDWQAGLVVAHAHEAGWRTVYTVHNLQYQGRWNLAEASGWSGLGPAWLTHEGAEFYGDLNLMKAGLIAANHVTTVSPQYAREITTQQYGEGLQGVLLRLTLEGRLSGIINGLDQERWNPRTDPDVPAYSDLAGKAAATQALRTEFGLDKAPVLGVVSRLADQKGMDLLIEALPRLVHNWNVVVLGGGDPLLTAALEGWAQHPRVSFAQGMNEALAHQIYAGSDAFAMPSRFEPCGLSQMIAMRYGTLPVVRETGGLVDTVPPDVGFRFQPATPEALVEACQQARAAFEDQSDWEARVARAMALDFSWDGPAREYLALYERVVTG
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: ILVC_CAUVC
Sequence: MRVYYDRDADLARILDRKIAIVGYGSQGHAHALNLRDSGIKNVAVALRAGSPTAKKAEGEGLKVMTVAEAAAWADLIMILAPDEHQAAIYKNEIALNIRDGAALLFAHGLNVHFGLIEPKDTIDVLMVAPKGPGHTVRGEYQKGGGVPCLIAVHHNATGNALDLGLAYASAIGGGRSGIIETNFREECETDLFGEQAVLCGGTVELVRAGFETLVEAGYAPEMAYFECLHELKLIVDLMYEGGIANMNYSISNTAEYGEYVTGPRIITPETKAEMKRVLEDIQSGKFVRDFMLENAVGQPSFKATRRRSAEHQIEEVGARLRGMMPWIAKNKLVDQAKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: SYN_PORGI
Sequence: MDKKMKRTRIADALHGGLVGQEINIKGWVRTKRGNKAVNFIALNDGSTIHNMQIVADLASFDAAQMSQITTGACIGVIGTLVESQGAGQSVEVQASAIEIYGTADPATYPLQKKGHTLEFLREIAHLRPRTNTFGAIYRIRHHMAIAIHTFFHNKGYYYFHAPLITASDCEGAGQMFQVTTLNPDSLPRTEEGQVDYRKDFFGRHTSLTVSGQLEGEMAAMALGGIYTFGPTFRAENSNTPRHLAEFWMIEPEVAFLEIEDNMDLAEEFIKYCVQWALDNCMDDISFLSEHFDKELIDRLKFVLEKPFVRLAYTEGIRILEEAVKNGVKFEFPIYWGADLASEHERYLVEVHFKTPVIMTDYPKEIKSFYMKLNDDGKTVRGMDVLFPKIGEIIGGSEREADYDKLVARANEMGVPEKDIWWYLDSRRYGTAPHSGFGLGFERLLLFVTGMSNIRDVIPFPRTPNNAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCMP_SYNE7
Sequence: MGVELRSYVYLDNLQRQHASYIGTVATGFLTLPGDASVWIEISPGIEINRMMDIALKAAVVRPGVQFIERLYGLMEVHASNQGEVREAGRAVLSALGLTERDRLKPKIVSSQIIRNIDAHQAQLINRQRRGQMLLAGETLYVLEVQPAAYAALAANEAEKAALINILQVSAIGSFGRLFLGGEERDIIAGSRAAVAALENLSGREHPGDRSRE
What is the function of this protein?
Probably part of the carboxysome shell, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) is sequestered.  It is thought that this protein controls transport of RuBisCO reactants in and out of the carboxysome; residual densities in the 4 X-ray structures suggest that differing compounds bind in interior pockets, depending on the open or closed state of the pore.
What are the official names of this protein?
Carboxysome shell protein CcmP, Carbon dioxide concentrating mechanism protein CcmP.
What is the protein family that this protein belongs to?
Belongs to the EutL/PduB family.
What are the subcellular locations of this protein?
Carboxysome. Note=This cyanobacterium makes beta-type carboxysomes.
Protein: RRF_YERPP
Sequence: MINEIRKDAEVRMEKCLEAFQNHISKIRTGRASPSILDGIQVEYYGTATPLRQLANIVVEDSRTLALTVFDRSLSAAVEKAIMTSDLGLNPSSAGTVIRVPLPALTEERRKDLIKVVRAEAEQGRVSIRNVRRDANDKVKALLKDKEISEDEDRRSQDDVQKLTDAYIKKVDAALAVKEAELMDF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_TROW8
Sequence: MFAVVKASGFQRLVEVGSVISIDPTNVDSGGFVHLPVLLLVDGAEVVSDPDKLRLARVSAKFLRKLRGPKVRIHKFKNKTGYHKRQGHRQGVYVFSVTSIERGD
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: SDF2_BOVIN
Sequence: MAVVSLLLFGGLWSAVGSSNLAVVTCGSVVKLLNTRHNVRLHSHDVRYGSGSGQQSVTGVTSVDDSNSYWRIRGKTATVCERGTPIRCGQPIRLTHVNTGRNLHSHHFTSPLSGNQEVSAFGEEGEGDYLDDWTVLCNGPYWVRDGEVRFKHSSTEVLLSVTGEQYGRPISGQKEVHGMAQPSQNNYWKAMEGIFMKPSELLKAEGHHTEL
What are the official names of this protein?
Stromal cell-derived factor 2, SDF-2.
What are the subcellular locations of this protein?
Secreted.
Protein: NADHK_ARATH
Sequence: MAIRKLLLLLKPIDPYPFLQTEGASLIKNPQVLQYLESRCKVHKNAIKFCQEILSKKPVEWKPISRNDLSHPIRDVDMVITVGGDGTLLHASHFIDDSVPVLGVNSDPTQAHEVEELSDQFDASRSTGHLCAATVENFEQVLDDILFGRVVPAKVSRISLKLNSETLLSHALNDILIAQPCPAAVSRFSFKIKNKDGASSPKTVNCRSSGLRICTAAGSTAAMQSAGGFVMPMLSRDLQFMVREPISPGSTASLMHSTFKPDQFMDVNWYSDHGTIYIDGCQVQHSVQLGDTIEISSDAPVLNVFLSHGISQIRSRY
What is the function of this protein?
Phosphorylates specifically NADH.  Can phosphorylate NAD with a 100-fold decrease in efficiency compared to NADH.  Prefers ATP as nucleoside triphosphate substrate.  Can also utilize UTP, GTP and CTP.  Key source of the cellular reductant NADPH which is an important antioxidant factor.
What are the official names of this protein?
NADH kinase, AtNADK-3.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.