PharMolix/UniProtQA huggingface dataset:
Protein: FOXK2_MOUSE
Sequence: MAAAAALSGAGAPPAGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGHSAAAPEPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEAPESPVKPVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLSLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLVEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGASQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPPAIKPVTYTVATPVTTPTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVAGQAVVTQAAVLAPPNPEPQENGDHREVRVKVEPVPAISPATLGAASRIIQTSQGTPVQTVTIVQQAPLGQHQLPIKTVTQNGAHVVPMPTAVHSQVNNAAASPLHMLATHASASASLPTKRQNGDQAEQPELKRVKAEDGESIVIALSVDAPPAAVREKAIQN
What is the function of this protein?
Transcriptional regulator involved in different processes such as glucose metabolism, aerobic glycolysis and autophagy (PubMed:25402684, PubMed:29861159, PubMed:30700909).  Recognizes and binds the forkhead DNA sequence motif (5'-GTAAACA-3') and can both act as a transcription activator or repressor, depending on the context (PubMed:25402684, PubMed:29861159, PubMed:30700909).  Together with FOXK1, acts as a key regulator of metabolic reprogramming towards aerobic glycolysis, a process in which glucose is converted to lactate in the presence of oxygen (PubMed:30700909).  Acts by promoting expression of enzymes for glycolysis (such as hexokinase-2 (HK2), phosphofructokinase, pyruvate kinase (PKLR) and lactate dehydrogenase), while suppressing further oxidation of pyruvate in the mitochondria by up-regulating pyruvate dehydrogenase kinases PDK1 and PDK4 (PubMed:30700909).  Probably plays a role in gluconeogenesis during overnight fasting, when lactate from white adipose tissue and muscle is the main substrate (PubMed:30700909).  Together with FOXK1, acts as a negative regulator of autophagy in skeletal muscle: in response to starvation, enters the nucleus, binds the promoters of autophagy genes and represses their expression, preventing proteolysis of skeletal muscle proteins (PubMed:25402684).  In addition to the 5'-GTAAACA-3' DNA motif, also binds the 5'-TGANTCA-3' palindromic DNA motif, and co-associates with JUN/AP-1 to activate transcription (By similarity).  Also able to bind to a minimal DNA heteroduplex containing a G/T-mismatch with 5'-TRT[G/T]NB-3' sequence (By similarity).  Binds to NFAT-like motifs (purine-rich) in the IL2 promoter (By similarity).  Positively regulates WNT/beta-catenin signaling by translocating DVL proteins into the nucleus (By similarity).
What are the official names of this protein?
Forkhead box protein K2, Cellular transcription factor ILF-1, Interleukin enhancer-binding factor 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MURG_RHORT
Sequence: MNASMPRDGALLVNAPLHIALAAGGTGGHVFPAEALAGELIRRGHKLTLITDKRGHVYGGTLGLLDTKRILAGGVAGRGVIGRLRGMIELAMGSLQAYGLLRRLRPDVVVGFGGYASVPTMLAAIRLKLPTVVHEQNAVPGRANRLLAARVSRYAVSFARAERPRGARPVVVGMPVRPSVLALRGEGYDAPRPGLDFRLLITGGSQGARVFATLVPQALALLSPAHRARLRVTQQCRPEDIEAVRATYEAQGIDALLSAFFSDLPERLRDAHLVICRSGASTVGELAALGRPAILVPFPHAIDDHQTANARGLDEVGGGWLMPQAALTPQALAERLGELMDDPDVLVRAAQCARGAGVPDAAVRLADLVSATADHRVPEMPPKEISA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RNH_RHILO
Sequence: MSKQVEIFTDGACSGNPGPGGWGAILRFNGTTKELSGGEAETTNNRMELLAAISALNALKEPCTVELHTDSKYVMDGISKWIHGWKKNGWKTADKKPVKNGELWQALDEANRRHKVTWNWVKGHAGHTENERADELAREGMAPFKKGSFKPAASAPKPDAQLKQPVATKARRSTQSY
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_PELPB
Sequence: MLAKRIIPCLDVRDGRVVKGINFEGLRDAGSILEQARFYNNELADELVFLDISASLESRKTTLEEVLKVSGEIFIPLTVGGGINSVERAREVFLHGADKVSVNTAAVNDPFLITRIAERYGSQAVVVAIDIKKTGEDYLVFTHSGKKPTCYEALEWAHKVQELGAGEILLTSMDRDGTKEGYDNDILAKISTSVHIPVIASGGAGNLEHLYDGFTKGHADAALAASIFHFRQHSIREAKEYLRQRGITVRI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RXL7_STAAR
Sequence: MSKEKVARFNKQHFVVGLKETLKALKKDQVTSLIIAEDVEVYLMTRVLSQINQKNIPVSFFKSKHALGKHVGINVNATIVALIK
What are the official names of this protein?
Putative ribosomal protein L7Ae-like.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
Protein: OSBL3_MOUSE
Sequence: MSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMTYTQEPPVQKGFLLKKRKWPLKGWHKRFFCLEKGILKYAKSQADIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEELFDEWVSKLRHHRMYRQNEIAMFPRDVNHFFSGSSVTDSAPGVFESVSSRKRSSLSKQNSFPPGSNLSFSCGGDTRVPFWLQSSEDMEKCSKDMAHCHAYLLEMSQLLESMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKSYSDGSEASSEFSKMQEDLCHVAHKVYFALRSAFNSISVEREKLKQLMELDTSPSPSAQVVGLKHALSSALAQNTDLKERLRRIHAESLLLDPPAVPKPGDNLAEENSRDEGRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLESSGEARSKRRTSLPAPGPNTSSVSLWSILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKASRIPSPLERMVYVAAFAISAYASSYFRAGSKPFNPVLGETYECIRQDKGFQFFAEQVSHHPPISACHAESGNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPAFGDHFEWNKVTSCIHNILSGQRWIEHYGEIDIKNLNDDSCHCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGASSSTCVWRANPMPKGYEQYYGFTQFALELNEMDPLSRSLLPPTDTRFRPDQRLLEEGNIEEAEVQKQRIEKLQRERRRVLEENGVEHQPRFFRKSSDDAWVSNGTYLELRKDLGFSKLDHPVLW
What is the function of this protein?
Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes.  Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments.  The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface.  With VAPA, may regulate ER morphology.  Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion.  Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3.  Also binds 25-hydroxycholesterol and cholesterol.
What are the official names of this protein?
Oxysterol-binding protein-related protein 3, ORP-3, OSBP-related protein 3.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Cell projection, filopodium tip. Nucleus membrane; Peripheral membrane protein. Note=Co-localizes with OSBPL6 at contact sites between the plasma membrane and the endoplasmic reticulum.
Protein: HOX8_ORYSJ
Sequence: MKRPSCRGSSMAIIHDTSDQQEDNMRSYMDGGGAAAYEEEEEEVEDDDGGGGGGGGGGGGGLGEKKRRLAAEQVRALERSFEADNKLDPERKARIARDLRLHPRQVAVWFQNRRARWKTKQIERDFAALRSRHDALRLECDALRRDKDALAAEIADLRDRVDGQMSVKLEAVAADEHQPPPPPPPPPLAYNSKVVDGSTDSDSSAVFNEEASPYSGAAIDHHHHQTPASYDTAGFTSFFAPSTTLTSSLSFPSMFHASSHFDGHQELLVGGGGAGAVADADLGGAGFFAGDEHAGGLSWYGAEGW
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HOX8, HD-ZIP protein HOX8, Homeodomain transcription factor HOX8, OsHox8.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class I subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MCTB_MYCLE
Sequence: MISLRQHAFSLAAVFLALAVGVVLGSGFLSDTLLSSLRDEKRDLYTQISGLNDQKNMLNEKVSAANNFDNQLLGRIVHDVLGGTSVVVFRTPDAKDDDVAAVSKIVVQAGGTVTGTVSLTQEFVDANSTEKLRSVVNSSILPAGAQLSTKLVDQGSQAGDLLGITLLVNANPAVPNVGDAQRSTVLVALRDTGFITYQTYNRNDHLGAANAALVITGGLLPQDAGNQGVSVARFSAALAPHGSGTLLAGRDGSATGVAAVAVARADAGMAATISTVDNVDAEPGRITAILGLHDLLSGGHTGQYGVGHGATSITVPQ
What is the function of this protein?
Pore-forming protein, which is involved in efflux of copper across the outer membrane.  Essential for copper resistance and maintenance of a low intracellular copper concentration (By similarity).
What are the official names of this protein?
Copper transporter MctB.
What is the protein family that this protein belongs to?
Belongs to the MctB (TC 1.B.50) family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: FMT_MANSM
Sequence: MKPLKIIFAGTPDFAAQHLQALLNSHHQVIAVYTQPDKPAGRGKKLQASPVKQLAEQYNIPVYQPKSLRKEEAQAQFAQLQADVMVVVAYGLILPKAVLEMPRLGCLNVHGSILPRWRGAAPIQRAIWAGDKQTGVTIMQMDEGLDTGDMLHKVYCDITAEETSASLYHKLATLAPPALIDVLDELESGKFIAEKQEDSKSNYAEKLSKEEAKLDWSLSAAQLERNIRAFNPAPVAFLTVPVNEAEERIKVYRAEVLPHQNSAAGTVLAFDKKGLRIATAEGVLNIQQLQPSGKKPMSVQDFLNGRADWFVLGQVLN
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: GLGC_BACAN
Sequence: MAQKQKCVAMLLAGGKGSRLSALTKNLAKPAVPFGGKYRIIDFTLSNCANSGIETVGILTQYQPLELHNYIGIGNAWDLDRVSGGVTVLPPYAESSGVKWYTGTASAIYQNLNYLSQYEPEYVLILSGDHIYKMDYSKMLDYHIEKEADVSISVIEVPWDEASRFGIMNTNEEMEIVEFEEKPQFPRSNLASMGIYIFNWAILKEYLEMDARNPESSNDFGKDVLPLLLDEGKKLMAYPFEGYWKDVGTVKSLWEANMDLLRDETSLNLNDRDWRIYSVNPNEPPQYIAEKAKVEESLINEGCVIEGDVKHSVLFQGVTVEEGSMVIDSVVMPGAKIGKNVVIERAIVGSEMVIEDGTIIRPEKNVDDVVLIAEGK
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: GCST_YERPP
Sequence: MAKQTPLYDQHVACGARMVDFHGWMMPLHYGSQIDEHHFVRQDAGMFDVSHMTIVDLHGNRTREFLRYLLANDVAKLTQPGKALYTGMLNESGGVIDDLIVYFLSEDYFRLVVNSATRDKDLAWISQHAEPYQVEVTVRDDLALIAVQGPQAQQKVATLLTTEQQQAIAGMKPFFGIQTGDLFIATTGYTGEAGYEIALPKQQVVAFWQQLLAAGVKPAGLGARDTLRLEAGMNLYGQEMDEKTSPLAANMGWTVAWQPEDRQFIGRAALERQRMKGTEQLVGLIMTEKGVLRNELPVYFFDAAGNQHVGVITSGSFSPTLGFSIALARVPAGIGEHAVVQIRNREMPVRVTKPGFVRAGKAIVL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: KRE28_CANGA
Sequence: MEAQLHELQEEITRSSDLVLTEQDKRLQGTLREIDQSIRKLIETSDYLKLSGDADSLIDIKQLEVKSRELDSLMDLLRKLYWREESLDLFLKYTINSDAEQVPVFSDTDPKYQSLQDEVSHLRDDVMTVKNQEIDQITGEILQVAHEITEKQDQVNMLYLETTNELDKCWELLDEWQRLQDDQRITKNEDNSNRKDTELNAMEECYEEWKTLEELAVLNDNLQKQIDELEKVDNKAINSTQLAEESIVNTVQLNDLIDMWKRRIIASIHEDISEIVLYPYSRKLQLRVANRYTIIIQLDKHQTHDGKSTIHDIDLFTEQDSRIIPMRELRKQVLQECKGHSNILQALKNIINRVINNDN
What is the function of this protein?
Required for kinetochore binding by a discrete subset of kMAPs and motors.  Involved in kinetochore-microtubule binding and the spindle assembly checkpoint (By similarity).
What are the official names of this protein?
Spindle pole body component KRE28.
What is the protein family that this protein belongs to?
Belongs to the KRE28 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Chromosome, centromere, kinetochore. Note=Localizes to the nuclear side of the spindle pole body.
Protein: PETG_DRANE
Sequence: MIEVSLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: LPTD_YERPA
Sequence: MKKRFPTLLATLIWTALYSQHTLADLAEQCMLGVPTYDQPLVTGDPNQLPVRINADKTEANYPDNALFTGNVIVQQGNSTLTANQVELTQVQKPGEVIPLRTVTATGDVNYDDPQIKLKGPKGWSNLNTKDTDMDKGKYQMVGRQGRGDADLMKLRDQSRYTILKNGTFTSCLPGDNSWSVVGSEVIHDREEQVVEVWNARFKIGKVPVFYSPYMQLPVGDKRRSGFLIPNAKFTSNNGFEFLLPYYWNIAPNFDATITPHYMERRGLQWQNEFRYLLAPGSGTMALDWLPNDRIYTGPDGTDKNATRWLYYWGHSGVMDQVWRFNINYTRVSDPAYFTDLTSQYGSTTDGYATQIFTAGYANENWNATLSSKQFQVFTAAGNSNAYRAQPQLDMNYYKNDVGPFDMHVYGQAAKFTSVNPTNPEASRFHIEPTVNLPLSNSWGSINTEAKLLATHYQQDIPASFADNASNPKLKDSVNRVLPQFKVDGKVVFDRSMDWATGFTQTLEPRAQYLYVPYRNQDDIYIYDTTLMQSDYSGLFRDRTYSGLDRIASANQVSTGLTSRIYDDARVERFNVSVGQIYYFSRSRTGNTEAIDNSNATGSLVWAGDTFWRINDQLGLKGGAQYDTRLGSLTLGNAIMEYRKDADRMIQLNYRYASPKYIQAAVPKVYNPDYQQGISQVGTTASWPIADRWAIVGAYYYDTKAKQPASQLVGLQYNTCCWAVNLGYERKITGWNAQGQTSKYDNKIGFNIELRGLSGGHSLGTAQMLNSGILPYQSAF
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: Y6190_DICDI
Sequence: MDILNYIKKNLKIRIETTNQLNDALKNKNLCSVEFDNKETWLSNTPLEEPNAYKNITHPSQLDGLENGDYHISSNLVVSILKEKLKEIEQLKQIIKSKDYDINYISAYGERKYPNGSKNE
What are the official names of this protein?
Uncharacterized protein DDB_G0284781.
Protein: ALR_LISW6
Sequence: MVTGWHRPTWIEIDREAIRANIKNEQHRLPENVALWAVVKANAYGHGIIETAKTAKEAGAKGFCVAILDEALALREAGFRNDFILVLGATRQEDANLAAKNNISLTVFREDWLHNLTLEAPLRIHLKVDSGMGRLGIRSTEEAKQIEARIALDHQLILEGIYTHFATADQLETSYFEQQLDKFTTILTSFESRPTFVHTANSAASLLQPQMDFDAVRFGISMYGLTPSLEIKNSLPFELKPALALYTEMVHVKELAPGDSVSYGATYTATEKEWVATLPIGYADGLIRHYSGYHVLVDGELAPIIGRVCMDQTIIKLPREFQTGSKVTIIGTDHGNTITADDAADYLGTINYEVTCLLSDRIPRKYIN
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: 50511_ASFP4
Sequence: MFSLQKKALQHIYMTPENASELTKDLLQHLGLYWNGPIIKMDTVVYLHNKIFSNRSVLKYALAKQANITIIKTLVLWVEPEYALAQALKHNRKDVLECIFSYHLTTPKYHHIMHLTSSQELFEFFHLFICKSKNYNARMECLLYAATLYNFPNILEKNREYIIRHSIGNSLFAIACKERHIHLIAWFVTAGVLDTYDDSTLFNTAFKLGDYSLLEVACDLPIIYPDYLIISMMQTAIQKNYFRFFKKLLTHFNIYRQIIITDAAYYNRRKILLLLLNQNIFNNFAILCALSAAIKGHASKKTLNLLISQLDSQMTVVDSVYYSIIKYNNIDCIPLLMQIKTFKIETLISIAVHGNNINIIAACKAFLPKDTLYHLVLKMAIVSRNYKLFKLYTEKENPMYIFTTIKAIISNLVNYTVVQAVAIEYLRKFHQERQLPIVPLLMVLAEHNYITKFKKTCYAANMSDQNVKRALIKCLFIASQKNYCQIFKYCFGSLLKVLSKHERVKFFNSVVFAKKLASYYDHQNMIHLIDSLIERFRYLIKD
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 505-11L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
Protein: SELO_CERS5
Sequence: MTFRFDNSYARELEGFYVDWQAAPVPAPRLLRLNRGLAGELGLDADRLEAEGAAIFSGKRLPEGAHPLAQAYAGHQFGGFSPQLGDGRALLIGEVTDRSGRRRDLQLKGSGRTPFSRGADGKATLGPVLREYLVGEAMHGLGIPTTRALAAVATGEPVLRQAGELPGAILTRVAASHIRVGTFQFFAARSDMERVRRLADYAIARHYPALAEAPEPYLAFYEAVADAQADLVARWMLVGFIHGVMNTDNMAISGETIDYGPCAFMEGFDPGTVFSSIDLQGRYAYGNQPFILAWNLARLGEALLPLFDADAGRAAEKANAVLGTVGARYQARWLEGMRAKLGLAGAEEGDLSLAEDLLAAMQGARADWTLTFRRLADAVTEDAALRPVLQGPDTLQSWLSRWRRRLGPEAARRIRAVNPIYIARNHRVEEALAAAHAGDLGPFDRLIGALSDPFTERAGLEDLAQPAPAGFNEGYRTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: TBL1Y_HUMAN
Sequence: MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPSALISILQKGLQYVEAEISINKDGTVFDSRPIESLSLIVAVIPDVVQMRQQAFGEKLTQQQASAAATEASAMAKAATMTPAAISQQNPPKNREATVNGEENGAHEINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQGTGGIFEVCWNARGDKVGASASDGSVCVLDL
What is the function of this protein?
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units.  Plays an essential role in transcription activation mediated by nuclear receptors.  Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange (By similarity).
What are the official names of this protein?
F-box-like/WD repeat-containing protein TBL1Y, Transducin beta-like protein 1Y, Transducin-beta-like protein 1, Y-linked.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EBI family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS21_DROVI
Sequence: MENDAGENVDLYVPRKCSASNRIIHAKDHASVQLSIVVVDPETGRQTDGTKTYAICGEIRRMGESDDCIVRLAKKDGLITKNF
What is the function of this protein?
May be an associated component of the ribosome rather than a core structural subunit.  May act as a translation initiation factor.  Has a role in regulation of cell proliferation in the hematopoietic organs and the imaginal disks of larva (By similarity).
What are the official names of this protein?
40S ribosomal protein S21, Overgrown hematopoietic organs at 23B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: LPXH_PSYIN
Sequence: MRTLFIADLHLSEKHPQISHAFFEFLQNETENVDALYILGDLFEVWIGDDERTLLMNEVALKLSEYALKNNILLYYIHGNRDFMIGKKYAKQSSMQLLPEHCEINLYGKKILILHGDTLCLADKNYQKMRTLLHNPLIQLVFNLLPLFLRKKIGWKIRHASQSKKVYKNREVMDVTKDEVVRLMEKHHVQTLIHGHTHRVACHEMLVKGQAAQRYDVGDWRHNLSYVEVQKDKINLVIRPINFYN
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ULAB_MYCPN
Sequence: MENKNLHIIAACGNGMGTSMLIKIKVEKIMKELGYTAKVEALSMGQTKGMEHSADIIISSIHLTSEFNPNAKAKIVGVLNLMDENEIKQALSKVL
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II UlaABC PTS system is involved in ascorbate transport.
What are the official names of this protein?
Ascorbate-specific PTS system EIIB component, Ascorbate-specific phosphotransferase enzyme IIB component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCDH_MACFA
Sequence: MALRGVSVQLLSRVPGLRVFRTWVSSAAQTEKVGRTQSQLAKSSRPEFDWRDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISQMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSPLVMHPIYAYGSEEQRQKYLPRLAKGELLGCFGLTEPNSGSDPSSMETRARYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGRIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENMLPGASSLGGSFGCLNNGRYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAFTASK
What is the function of this protein?
Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism.  It uses electron transfer flavoprotein as its electron acceptor (By similarity).
What are the official names of this protein?
Glutaryl-CoA dehydrogenase, mitochondrial, GCD.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: KPRS_CORAM
Sequence: MSTQYLNSNLKVFSLNSNKELAEQIAKHIGVGLGKCSVDRFSDGEVQINIEESIRGCDVFIIQSTSFPVNEHIMELLIMIDALKRASAKTINIVIPYYGYARQDRKARSREPITSKLVANLLETAGATRVITLDLHAPQIQGFFDIPIDHLMGVPILSDYFETKGLKDIVIVSPDHGGVTRARKMADRLKAPIAIIDKRRPRPNVSEVMNIIGNIEGKTALLIDDIIDTAGTITLAANALVENGASEVYACCTHPVLSGPAIERIQNSNIKELVVTNSIVLPEEKKIDKVHELSVAPLIGEAIIRVYEEESVSVLFN
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_CLOB8
Sequence: MSDRSSRRERITKETSVRVEIDLDGNGNSEINTGIGFLDHMLTLFSFNSKVNLDVFAKGDSYVCDHHTIEDIGITLGEAFKESLGDKHGINRYGTFYVPMDETLALASIDVSNRPFLVFDCDFKREKVGEMSTEMVVEFFRAFAFNAGITLHLKVLYGENDHHKIEALFKAFGRAIKEAISRSSDNDIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.