PharMolix/UniProtQA huggingface dataset:
Protein: NOA1_MOUSE
Sequence: MLPARLACGLLCGLRRGPAPAAACYGPARWLLEGKCEVPIRQRASSLGRRVPPSSTATEDYAEGPDTEERFLFPEYVPERTPEEQVRELQELRELQQLQQEKERERLQQREERLQQKLRAGFRTLPVPEFPDASVPPSGIYCSGCGAELHCQHPGLPGYLPEEKFRDAAQAEGGPARTVCQRCWLLVHHGRALRLQVSRDQYLELVSAALRRPGPALVLYMVNLLDLPDALLPDLPKLVGPKQLIVLGNKVDLLPQDAPGYLKRLRKRLWDDCIRAGLVVAPGHQGPQYPAGDEPLEEIKNQNPSSRSRTVVKDVRLISAKTGYGVEEMISALQRSWRYRGDVYLVGTTNAGKSTLFNTLLESDYCTAKGSEAIDRATISPWPGTTLNLLKFPICNPTPYRMFKRQRRLQEDATKAEEDLSEEEQSQLNQLKKHGYIVGRVGRTFSYSREQDEVPFEFDADSLAFDMGSEPVVSVCKSTKQIELTPEDVKDAHWFYDTPGITKESCILNLLTEKEINTVLPTHSIIPRTFVLKPGMVLFLGGIARIDFLQGNQSAWFTVVASNFLPVHITSLDKADALYEKHAGHELLLVPMGGKERMAQFPPLVAEDITLKGGGKFEAVADIKFSSAGWVAVTPYSEGTLHLRGHTPEGTALTVHPPVLPYIVNVKGQRMKKSVAYKTKKPPSLVHNLKKHR
What is the function of this protein?
Involved in regulation of mitochondrial protein translation and respiration.  Plays a role in mitochondria-mediated cell death.  May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes.  Binds GTP.
What are the official names of this protein?
Nitric oxide-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. NOA1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: HSPB3_HUMAN
Sequence: MAKIILRHLIEIPVRYQEEFEARGLEDCRLDHALYALPGPTIVDLRKTRAAQSPPVDSAAETPPREGKSHFQILLDVVQFLPEDIIIQTFEGWLLIKAQHGTRMDEHGFISRSFTRQYKLPDGVEIKDLSAVLCHDGILVVEVKDPVGTK
What is the function of this protein?
Inhibitor of actin polymerization.
What are the official names of this protein?
Heat shock protein beta-3, HspB3, Heat shock 17 kDa protein, HSP 17, Protein 3.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to nuclear foci during heat shock.
Protein: SECY_PSEAE
Sequence: MAKQGALSALSNGGLSELWARLRFLFLAIIVYRIGAHIPVPGINPDRLAALFRQNEGTILSLFNMFSGGALERMSIFALGIMPYISASIIMQLMTAISPQLEQLKKEGESGRRKISQYTRYGTVVLALVQAIGMSVGLGSQGVAFSNDFGFYFVAVTTFVAGAMFMMWLGEQITERGVGNGISMLIFAGIVAGLPRAIGQSFESARQGDINIFALIGVGLLAVAIIAFVVFIERGQRRIAVHYAKRQQGRKVFAAQTSHLPLKVNMAGVIPAIFASSILLFPASLGSWFGQSEGLGWLQDVAQAIAPGQPLNILLFTAGIVFFCFFYTALMFNPKDVAENLKKSGAFIPGIRPGEQSARYIDGVLTRLTMFGALYMTAVCLLPQFLVVAAHVPFYLGGTSLLIVVVVVMDFMAQVQSHLVSHQYESLMKKANLKGYGSGMLR
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TERPB_PSESP
Sequence: MPRVVFIDEQSGEYAVDAQDGQSLMEVATQNGVPGIVAECGGSCVCATCRIEIEDAWVEIVGEANPDENDLLQSTGEPMTAGTRLSCQVFIDPSMDGLIVRVPLPA
What is the function of this protein?
The oxidation of alpha-terpineol by cytochrome p450-TERP requires the participation of a flavoprotein, terpredoxin reductase, and an iron-sulfur protein, terpredoxin, to mediate the transfer of electrons from NADH to P450 for oxygen activation.
What are the official names of this protein?
Terpredoxin, TDX.
What is the protein family that this protein belongs to?
Belongs to the adrenodoxin/putidaredoxin family.
Protein: HIS7_SODGM
Sequence: MNQKVLFIDRDGTLINEPPADFQVDRMDKLALEPGVIPVLLALQKAGFRLVMITNQDGLGTTSFPQADFDGPHDLMMAIFTSQGIVFDEVLICPHLPTDGCACRKPQTGIVTPWLKEHALDSAHSYVIGDRETDMALAANMGITGLRYQRASLNWPAIGEQLTRSDRHARVNRVTRETAIDVEVWLDREGDSRINTGIGFFDHMLDQIATHGGLRINIAVKGDLHIDDHHTVEDTALALGEALNKALGDKRGIGRFGFVLPMDECLARCALDISGRPHLEYKAKYSFQRVGDLSTEMVEHFFRSLSYAMACTLHLRTKGKNDHHRVESLFKAFGRTLRQAIRVEGDTLPSSKGVL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_BURO1
Sequence: MALAKRIIPCLDVTAGRVVKGVNFVELRDAGDPVEIARRYDDQGADELTFLDITATSDQRDLILPIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVSMNSSAVANPQLVRDAADKYGSQCIVVAIDAKRVSADGETPRWEVFTHGGRKNTGLDAIEWARKMAELGAGEILLTSMDRDGTKSGFDLALTRGVSDAVPVPVIASGGVGSLQHLADGIKDGRADAVLAASIFHYGEHTVGEAKRFMSDQGIPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
Protein: LPSB_RHIME
Sequence: MVDIRDVEVIAPNFKQRLSGVTSTIIQLVPVQRALGQKIAVLGPGLPKSLPSVRFRDLIHLWKRPEGRPCRVWHARRNVEMLPAILLRDLLRMKLRIVFTSASQRRHTGWSKFLIRRMDAVIATSGRTAAYLDVPNTVILHGIDTKRFQPPFDKTEAKKALGLDPAKKFVGCFGRVRHQKGTDLFVDSMIALLPCRPDWGAIVAGRATGPHLAFESELKERVAKAGLADRILFVGEHTNIPDWYRALDLFVAPQRWEGFGLTPLEAMATGVPVVATDVGAFSELVTGGSEETGLIIAADDLKAMVDAAAAFMDDRPRLAAASANGLARTSKNFAIEQEARAIAAVYESLMR
What is the function of this protein?
Acts at transfer of mannose group to a 3-deoxy-D-mono octulonic acid (KDO) via an alpha-1,5 linkage.
What are the official names of this protein?
Lipopolysaccharide core biosynthesis mannosyltransferase LpsB.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: RSMC_ECO55
Sequence: MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRAHTQQFHHWQVLSRQMGDNARFSLVATVDDVADCDTLIYYWPKNKPEAQFQLMNLLSLLPVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDADKFWGEYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLAANGVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQTSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRAIMTRQAKKG
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLD_BACC0
Sequence: MQTVRMTTAQALVKFLNQQYVEFDGKQQKFVKGIFTIFGHGNVVGLGQALEEDAGELEVYQGRNEQGMANAAMAFAKQKHRKQIMACTSSVGPGSANMITSAATASANNIPVLLLPGDVFATRQPDPVLQQIEQTHDLSISTNDAFRAVSKYWDRINRPEQLMTAMIQAMRVLTNPADTGAVTICLPQDVQGEAWDFPSYFFQKRVHRIERRLPTKASLADAVEMIKRKKKPVMICGGGVRYAEAAEELKQFAETFHIPFGETQAGKSAIESSHPYNLGGIGVTGNVAANTIAKEADLVIGIGTRFTDFTTASKQLFQNEEVEFLNINISEFHANKLDALKVIADAKEALLALIDELQEIDYQSSYTVEIADAKDAWETELSRLHNIRFTCQDFTPEVEGHFDENLNEYVDALGTQLTQTAVIGQINTLLDEDAIIVGAAGSLPGDLQRMWASRKPNTYHMEYGYSCMGYEVAGALGAKLAEPSKEVYAMVGDGSYQMLHSELVTSLQENKKINVLLFDNSGFGCINNLQMGNGMGSFGTEFRYRNQETRKLDGAIMKIDFAASAAGYGVKTYHVTSLEQLQEALIDAKKQTVSTLIDIKVLPKTMTNGYESWWHVGVAEVSKNQSVQAAYESKVSNLQQARSY
What is the function of this protein?
Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).
What are the official names of this protein?
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase, THcHDO hydrolase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: Y2518_STAA3
Sequence: METLELQGAKLRYHQVGQGPVLIFIPGANGTGDIFLPLAEQLKDHFTVVAVDRRDYGESELTEPLPDSASNPDSDYRVKRDAQDIAELAKSLSDEPVYILGSSSGSIVAMHVLKDYPEVVKKIAFHEPPINTFLPDSTYWKDKNDDIVHQILTEGLEKGMKTFGETLNIAPIDAKMMSQPADTEEGRIEQYKRTMFWLEFEIRQYTHSNITLDDFTKYSDKITLLNGTDSRGSFPQDVNFYINKETGIPIVDIPGGHLGYIQKPEGFADVLLNMWG
What are the official names of this protein?
Uncharacterized hydrolase SAUSA300_2518.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: YYAC_BACSU
Sequence: MNRKGGLFSSQERVKQYVSHTDAAAAKQIQTILSSSLRKAAGKPIVVVCIGTDRSTGDSLGPLVGMKLKQMQLTRFHVYGTLSDPVHAVNMKDKINDIHKLHKNPFVIAVDACLGRVKSVGSFQIGDGPLKPGAGVQKDLPEVGDLHINGIVNVSGFMEYFVLQNTRLNLVMNMANVLAEGLSLTDRTEWRQERLNPLQRLTGRI
What are the official names of this protein?
Uncharacterized protein YyaC.
Protein: GPI10_TRYBB
Sequence: MPWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAVVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVRDGPRINRLDVIATCYTVPGYSYMHKKVNHLGFVDCSIDLDEKTGLPKVTEDIMFRRYPKEYVLWRYDGKHSFNMSDLEESRKASELQSVVMPKSAPHPDAMVMTRAVAKEIEEPFLKRHGYRLYRTFLHSPLTLAPYEDIYIQMWVKVTK
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
What are the official names of this protein?
GPI mannosyltransferase 3, GPI mannosyltransferase III, GPI-MT-III, Glycosylphosphatidylinositol-anchor biosynthesis protein 10, TbGPI10.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family. PIGB subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CC14B_HUMAN
Sequence: MKRKSERRSSWAAAPPCSRRCSSTSPGVKKIRSSTQQDPRRRDPQDDVYLDITDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETSYIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSGVDDISINGVENQDQQEPEPYSDDDEINGVTQGDRLRALKSRRQSKTNAIPLTVILQSSVQSCKTSEPNISGSAGITKRTTRSASRKSSVKSLSISRTKTVLR
What is the function of this protein?
Dual-specificity phosphatase involved in DNA damage response.  Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C).  Dephosphorylates SIRT2 around early anaphase.  Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis.  Preferentially dephosphorylates proteins modified by proline-directed kinases.
What are the official names of this protein?
Dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Following DNA damage, translocates from the nucleolus to the nucleoplasm and interacts with FZR1/CDH1.
Protein: RH24_ARATH
Sequence: MSNRKFGMEGFGINRQTSYSFERSQAPQRLYVPPSSRGGDNSEDADLDNIDYMENEEAEEDIEEGGSAAASGGEVDEIDPLDAFMEGIHQEMKSAPPPKPKEKLERYKDDDDDPVESYLKAKKDLGLTLAADALNAGYNSDEEVYAAAKAVDAGMLDYDSDDNPIVVDKRKIEPITALDHSSIDYEPINKDFYEELESISGMTEQETTDYRQRLGIRVSGFDVHRPVKTFEDCGFSSQIMSAIKKQAYEKPTAIQCQALPIVLSGRDVIGIAKTGSGKTAAFVLPMIVHIMDQPELQRDEGPIGVICAPTRELAHQIFLEAKKFSKAYGLRVSAVYGGMSKHEQFKELKAGCEIVVATPGRLIDMLKMKALTMMRASYLVLDEADRMFDLGFEPQVRSIVGQIRPDRQTLLFSATMPWKVEKLAREILSDPIRVTVGEVGMANEDITQVVNVIPSDAEKLPWLLEKLPGMIDEGDVLVFASKKATVDEIEAQLTLNSFKVAALHGDKDQASRMETLQKFKSGVHHVLIATDVAARGLDIKSLKTVVNYDIAKDMDMHVHRIGRTGRAGDRDGVAYTLVTQREARFAGELVNSLVAAGQNVPPELTDLAMKDGRFKSKRDGRKGGKKGRGGGGGNKGVRGVDFGLGIGFSSESSRTPSSKAAPSRSGAINSVRTGVMAQFKNSFVAATPSNPQNQAYPNKRPSLMGFVSGGTIGGDMGRTQSQAPPVAPTQNASSHNSSQNHSQSSENRPRERKRRSGWDN
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 24.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
Protein: PAGR_ARATH
Sequence: MAELRHSSSLGSRSSSSPLRAAGDEDSSSPHVHDHSPNGGDDEDGRPRHPSRDRDRPIWFHSLFPFFGDDPRVSPQKNKISLLLILILAIASLISVYGIINHLNAPYLCKKDGIVLNCPHVKESPSPWENPLSATTSWKPCAERRIGGISDLPPENETNGYVFIHAEGGLNQQRIAICNAVAVAKIMNATLILPVLKQDQIWKDTTKFEDIFDVDHFIDYLKDDVRIVRDIPDWFTDKAELFSSIRRTVKNIPKYAAAQFYIDNVLPRIKEKKIMALKPFVDRLGYDNVPQEINRLRCRVNYHALKFLPEIEQMADSLVSRMRNRTGNPNPYMALHLRFEKGMVGLSFCDFVGTREEKVKMAEYRQKEWPRRFKNGSHLWQLALQKRKEGRCPLEPGEVAVILRAMGYPKETQIYVASGQVYGGQNRMAPLRNMFPNLVTKEDLAGKEELTTFRKHVTSLAALDFLVCLKSDVFVMTHGGNFAKLIIGARRYMGHRQKSIKPDKGLMSKSFGDPYMGWATFVEDVVVTHQTRTGLPEETFPNYDLWENPLTPCMCKA
What is the function of this protein?
Glycosyltransferase involved in the biosynthesis of pectic type-II arabinogalactans.
What are the official names of this protein?
Protein PECTIC ARABINOGALACTAN SYNTHESIS-RELATED, O-fucosyltransferase 26, O-FucT-26, O-fucosyltransferase family protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase GT106 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: DOHH_CANAL
Sequence: MSADEVNIDTASLEELRDILINKTGNTKLANRFRALFNLKSVGSEDSDKERAHKAIKYIAECFNDDSELLKHEVAYVLGQTKDLYAAPYLREVLENDNQQCMVRHEAAEALGALGDKESLPLLEKYFKEDPLLEIRQTCELAIERIHWENSEKAKNEVLEKSLYTSIDPAPPLATNDSTSKVEKLKEILNDQDKPLFERYRAMFRLRDIGTDEACLALASGFDDPSALFKHEIAYVFGQMCNPVTVPSLIKVLKDESEAGMVRHEAAEALGSIATDECLPVLQSFLNDSEPVVRDSAIVALDMYEYENSNELEYATVK
What is the function of this protein?
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
What are the official names of this protein?
Deoxyhypusine hydroxylase, DOHH, Deoxyhypusine dioxygenase, Deoxyhypusine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine hydroxylase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HSP1_DASHA
Sequence: MARYRRRSRSRSRSRYRRRRRRRSRGRRRRTYRRSRRHSRRRRGRRRGYSRRRYSRRGRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DPOL_DHBV3
Sequence: MPQPLKQSLDQSKWLREAEKQLRVLENLVDSNLEEEKLKPQLSMGEDVQSPGKGEPLHPNVRAPLSHVVRAVTTDLPRLGNKLPARHHLGKLSGLYQMKGCTFNPEWKVPDISDTHFDLEVINECPSRNWKYLTPAKFWPKSISYFPVQAGVKPKYPDNVMQHESIVGKYLTRLYEAGILYKRISKHLVTFKGQPYNWEQQHLVNQHQIPDGATSSKINGRQENRRRRTPIKSTCRQNDTKRDSDMVGQVSNNRSRIRPCANNGGDKHPPATGSLACWGRKASRVIKSGSSRDSSASVDSRRRSKGPRGFSTLPRRETTGNDHHSSDISNSVEATTRRRSTPGESITLGDSSIIPDGTSCASDKDSSPKEENVWYLRGNTSWPNRITGKLFLVDKNSRNTTEARLVVDFSQFSKGKNAMRFPRYWSPNLSTLRRILPVGMPRISLDLSQAFYHLPLNPASSSRLAVSDGQWVYYFRKAPMGVGLSPFLLHLFTTALGSEISRRFNVWTFTYMDDFLLCHPNARHLNSISHAVCSFLQELGIRINFDKTTPSPVTEIRFLGYQIDEHFMKIEESRWKELRTVIKKIKVGEWYDWKCIQRFVGHLNFVLPFTKGNIEMLKPMYAAITNQVNFSFSSAYRTLLYKLTMGVCKLRINPKSSVPLPRVATDATPTHGAISHITGGSAVFAFSKVRDIHIQELLMTCLARIMIKPRCLLSDSTFVCHKRYQTLPWHFAVLAKQLLKPIQLYFVPSKYNPADGPSRHRPPDWTAFPYTPLSKAIYIPHRLCGT
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery (By similarity).
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: ARGA_ACTP2
Sequence: MRNTELVQWFRQSTPYVNMHREKTFVIMLDGNAIAHPNFINITNDIGLLHSLGIKLVIVFGARCQIDELLAKNQMSSTYHKHIRITDSKTLEVVKQAVGGLHYDIFSRLSLRLPNSPVLNVVSSNAVLAQPLGVIDGVDYGLSGKIRRINIEGIQQQLAQDAIVVIGPIAPSVTGEMFNLPFEEIATQIAIKLKADKLIGFCDQQGILDSEGNVLSDLHPREAKRYLTQFIESGQYHHSAARFLQAAIEACHAGIKRSHLLSYKEDGSLLQELFSRDGIGTQLSEESSENIRLATSFDIPGLLNLIRPLEEQGILVKRSREQLEMEISNYTIIERDGIVIACAALNHYPQEKMAEMACVAVHPDYRDSSRGDVLLEAIKRRAYKLQVEKLFVLTTRTTQWFQERGFVLSTTDDLPKEKREHYNYQRMSKILILDLGQ
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP14_YEAST
Sequence: MAEAVLENVNVPAVVSKDECIYCFESPYNEPLALNASPKHSLNICLNCFQATCNRHVPLHIRVTEYACDTIHSNYLTIAKVEKPKQENVEENNNNKKIKLQVIETSEDDTHNTIWSLQRFNGENVPRTVLSKSTDSDISSTALEKIEKILKAKSQDFEDKKNSWVLEISTCPHTENFQIPSKPENTVNLNQCSSCDLTQNLWLCLHCGNIGCGREQIGIDGHSHALDHYRSNNNHPLAIKLGSLSSSTYDLYCYACDDETRFPDNVNLGSALQIYGINIQEKIADEKTLVQLQVEQNENWQFRMVDSSGKEFEKLSASKNYGCGLINLGNSCYLNSVIQSLVNGGVPNWSLDFLGSKFPLDVVYPDNNLKCQWIKLLNAMKCEPELYPNGIKPTTFKKCIGQNHQEFSSNRQQDAMEFLTFLLDLLDKKFFSSSSSGIPNPNDLVRFMMEDRLQCNICGKVKYSYEPTEAIQIPLEENDEPQDMLERIKAYFEGQTIEFKCANCKEKVTANKKPGFKSLPQTLILNPIRIRLQNWIPVKTSNELSLPGLIDRDDMLDVSSYLSQGFDPQTENLLPDEDENRSSFTPNQCSISQLIEMGFTQNASVRALFNTGNQDAESAMNWLFQHMDDPDLNDPFVPPPNVPKKDKREVDEVSLTSMLSMGLNPNLCRKALILNNGDVNRSVEWVFNNMDDDGTFPEPEVPNEEQQQKKDLGYSTAKPYALTAVICHKGNSVHSGHYVVFIRKLVADKWKWVLYNDEKLVAADSIEDMKKNGYIYFYTRC
What is the function of this protein?
Required for the adaptation to the presence of glucose in the growth medium; mediates the degradation of enzymes involved in gluconeogenesis when cells are shifted to glucose-containing medium (PubMed:12686616).  Required for proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBP1) (PubMed:12686616).  Accelerates proteasomal breakdown of ubiquitinated proteins as it disassembles free ubiquitin chains that would compete with ubiquitinated proteins to bind to the proteasome (PubMed:9305625).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Glucose-induced degradation protein 6, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease 14.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPF_AROAE
Sequence: MNLNATLIAQLVVFFILAWVTMKFVWPPIVKALDERAKKIADGLAAADKAKADLSLAEKKVVDELRKARESAGDVRASAEKQAAKFLDDARAEAARIIAQAREAAEAEAGTAAQRAKEALRDQVAHLAVAGAEKILRREINAQVHADLLANLKTELQ
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PURA_PSEAE
Sequence: MGKNVVVLGTQWGDEGKGKIVDLLTEQAAAVVRYQGGHNAGHTLVIDGEKTVLHLIPSGILREGVQCLIGNGVVLAPDALLREITKLEEKGVPVRERLRISPSCPLILSYHVALDQAREKARGEAKIGTTGRGIGPAYEDKVARRGLRVGDLFHRERFAAKLGELLDYHNFVLQHYYKEPAIDFQKTLDEAMEYAELLKPMMADVAATLHDLRKHGKDIMFEGAQGSLLDIDHGTYPYVTSSNTTAGGTATGSGFGPLYLDYVLGITKAYTTRVGSGPFPTELFDDVGAYLAKRGHEFGATTGRARRCGWFDAVILRRAIEINSISGLCLTKLDVLDGLDVVRLCVGYKNADGDVLEAPTDADSYIGLQPVYEEMPGWSESTVGAKTLEELPANARAYIKRVEELVGAPIDIISTGPDRNETIILRHPFA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CU1A_CONPB
Sequence: DECCAIPFCAKIFPGRCP
What are the official names of this protein?
Conotoxin pc1A.
What are the subcellular locations of this protein?
Secreted.
Protein: FTSZ_ECOL6
Sequence: MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNTDAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAAGMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSLITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMSEMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFETVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQPVMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: ATPE_STRPJ
Sequence: MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAVLAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLRAERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: UBIA_METFK
Sequence: MKNPSLRQKLEAYYRLTRLDKPIGILLLLWPTLWGIWLASPGWPDGLVLFVFIAGTVLMRSAGCVMNDLADRNFDGHVERTRQRPLVTGDVTTKEAVLLALALSLVAFILVLQLNPLVVALSFPALFLAASYPLTKRFLSIPQAYLGIAFGFGIPMAFAAITGQLPLEAWILLLANVFWAIAYDTEYAMVDRNDDLNIGIRSSAIFFGRLDVFAVMACYGAFLILMAWVGVRLQQSWPYFAGLGVAALVALYHYALIRDRDRQSCFKAFLHNNWLGAAIFVGVLASDYFRSSILSI
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.