PharMolix/UniProtQA huggingface dataset:
Protein: STS_HUMAN
Sequence: MPLRKMKIPFLLLFFLWEAESHAASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTPSRAAFMTGRYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGKWHLGMSCHSKTDFCHHPLHHGFNYFYGISLTNLRDCKPGEGSVFTTGFKRLVFLPLQIVGVTLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLFLGFLHYFRPLNCFMMRNYEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFAGKSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRIIDGRDLMPLLEGKSQRSDHEFLFHYCNAYLNAVRWHPQNSTSIWKAFFFTPNFNPVGSNGCFATHVCFCFGSYVTHHDPPLLFDISKDPRERNPLTPASEPRFYEILKVMQEAADRHTQTLPEVPDQFSWNNFLWKPWLQLCCPSTGLSCQCDREKQDKRLSR
What is the function of this protein?
Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid.
What are the official names of this protein?
Steryl-sulfatase, Arylsulfatase C, ASC, Estrone sulfatase, Steroid sulfatase, Steryl-sulfate sulfohydrolase.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, microneme membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MNMC_HAES1
Sequence: MFTVTPAKIYLNQEKTPVSEQFNDVYFSNQDGLAESEYVFQQGNHLWERWIVYQEKHFVIAETGFGTGLNFLAVTSLFRQFRQQYPDFPLKRLFFISFEKYPLPKDQLQQIHRLYPQFSALSQQLCDYCLDAIQGCQRFHFAETTLDLWFGDIADNLPQLGDYMQNRIDAWFLDGFSPSKNPQMWNDKLYQQIFYYSKPQGTFATFTAASAVRKGLISAGFEVQKRKGYGKKRECLCGIKNSTQQQNAKFPWYLNQPASLLSEDIAIIGGGIASLFTALSLLKRGAKVTLYCEDEQLALNASGNKQGAFYPQLSDDDDRNIRFYVHAFFYALQQLQWAIKQGIEFEHEFCGVALCAYDHKSAVKLAKISSYQWSKSLYQNLNKEQLSEKIGLPLDCAGGFIPQGAWLAPRQFVQNAFSYLQQLGLEIKTSQKITALDYRNLQWVLTNEQNETFNHQVVVLANGYQITDFVQTAKLPLYPVRGQVSQIPTSANLLKLKSVLCYDGYLTPADKMKQSHCLGASHIRNNKDRHFSHQEQRENQQKIQQNLASTDTDKNMDWLQDIDISANIARIGVRCSVRDRVPIMGNVPHFEQQCLDYRNIFNLRRRKQPIPDAAQWKNLYLIGALGSRGLTSAALLGETLASLIYAEPLPLSEDILHNLSPNRSWIRKLLKGTEIK
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_KLEP7
Sequence: MTTRTPSSGWLSRLAQGSLVKQILIGLVLGVLLALVSKPAAIAVGLLGTLFVGALKAVAPVLVLMLVMASIANHQHGQKTSIRPILFLYLLGTFSAALTAVLFSFLFPSTLHLTTAADSITPPSGIVEVLRGLLMSMVSNPIDALLNANYIGILVWAVGLGFALRHGNDTTKNLINDVSHAVTFIVKVVIRFAPLGIFGLVSSTLATTGFETLWGYAQLLLVLVGCMLLVALVINPLLVFWKIRRNPYPLVLTCLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVHTLNIPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGIPNDVAMQVVAVGFIIGVLQDSCETALNSSTDALFTAAACMAEDDQLAKNALRG
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CO6A6_HUMAN
Sequence: MMLLILFLVIICSHISVNQDSGPEYADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDNVEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQNMTHIIKDVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALKDIRNQVVQEICTEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQYFSPTKGARPNIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIEDDLVFGICSPREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFSDHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDCEIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFGNTHIGAALREVEHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTAGESNCFVDVVVGFDVSTQEKGQTLLEGQPWMETYLQDILRAISSLNGVSCEVGTETQVSVAFQVTNAMEKYSPKFEIYSENILNSLKDITVKGPSLLNANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVEKLEQKSDELRKEGLNALITVALDGPADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLSKQLVNVAERTCCCLFCKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHGKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHLVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPGAHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHPLDHHLVQLGRIHKPDHSYGVKFVKSFINSIRRAINKYPPINLKIKCNRLNSIDPKQPPRPFRSFVPGPLKATLKEDVLQKAKFFQDKKYLSRVARSGRDDAIQNFMRSTSHTFKNGRMIESAPKQHD
What is the function of this protein?
Collagen VI acts as a cell-binding protein.
What are the official names of this protein?
Collagen alpha-6(VI) chain.
What is the protein family that this protein belongs to?
Belongs to the type VI collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Deposed in the extracellular matrix of skeletal muscle.
Protein: RK14_GRATL
Sequence: MIQIQSYLNIADNSGARKIMCIQVLGSNNPHYANIGDIIIGVVKDALPNMPIKKSDIIRAVIVRTKKTIRRNDGMSIRFDDNAAVIINQENNPRGTRVFGPIAKELRDKNFSKIISLAAEVV
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FA50A_XENTR
Sequence: MAQYKGAASEAGRAMQLMKKREKQREQLEQMKQKIAEENVVKANINKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQFKDLQLKLEKQRERERKKEQKRKIASLSFNLEEDEECEDEEADDDYDDEEDDDDEDDDDDDAEKEELPKKKKKLGKNPDVDTSFLPDRDREEEENRLREELRQEWERKQEKIKSEEIEITFSYWDGSGHRRTVKMKKGNSIQQFLQKALEILRKDFSELRSAGVEQLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHEDVRLLSDATVEKDESHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDKYTIR
What is the function of this protein?
Probably involved in the regulation of pre-mRNA splicing.
What are the official names of this protein?
Protein FAM50A.
What is the protein family that this protein belongs to?
Belongs to the FAM50 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISCU1_ARCFU
Sequence: MYSDKVFDHFQNPRNVGKIEDADGVGTVGNPVCGDLMTIYIKVKDNRIEDIKFQTFGCAAAIATSSMATEMAKGKTIEEALKITRDAVAEALGGLPKQKMHCSNLAADALRRAIVDYFRKNGKIDKIKELGLEKELEKMEKGEMDDHGEYCEA
What is the function of this protein?
A scaffold on which IscS assembles Fe-S clusters.  Subsequently gives the nascent cluster to other proteins.  It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity).
What are the official names of this protein?
Iron-sulfur cluster assembly scaffold protein IscU 1, Sulfur acceptor protein IscU 1.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
Protein: RL3_MYXXD
Sequence: MKGLIGKKIGMTQVFNDEGNLVPVTVIDVGTCQVVGKRTPEKDNYSAVTIGFGEIREKILNLAERGFFKKANAPYRRHLKEFRVTPEEAASFNVGDAVKADMFAKGELVDVTGITKGRGFSGVMRRWNFKGSQTKTHGTHEYQRHPGAIGQRKTPGRVYPNKKMPGHYGVDQVTTQNLTVVDVDVEKGLVLVKGAVAGHNNGVVYIRPSIKAAMRAQHKAARGA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RUVC_MYCPA
Sequence: MRVMGVDPGLTRCGLSVVESGRGRTVVALDVDVVRTPSDAPLAERLLSISDAVEHWLATHQPDVVAIERVFSQLNVTTVMGTAQAGGVVALAAAKRGIGVHFHTPSEVKAAVTGNGAANKAQVTAMVTRILALQAKPTPADAADALALAICHCWRAPMIARMARAEALAAQQRQKYKDKVDATLRAAR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: HEMH_NOSP7
Sequence: MGRVGVLLLNLGGPDKLEDVGPFLYNLFSDPEIIRLPFRWLQKPLAWFIASRRTRTSQQNYKQIGGGSPLRRITEAQGEALKKQLGYLGQEANIYVGMRYWHPYTEEAIAQITQDNIEHLVILPLYPQFSISTSGSSFRLLDKLWQEEPKLQPIEYTVIPSWYKQPGYLQAMAELIAQELEQFPNPDEVHIFFSAHGVPKSYVEEAGDPYQQEIEECTALIMQTLNRPNAHTLAYQSRVGPVEWLQPYTEDALKELGAQGVKDLVVVPISFVSEHIETLQEIDIEYREVAEESGIHNFRRVPAPNTHPVFINALAELVIDALKNPSFKLSQAAQMKKMVKMYPQERWEWGLTTSAEVWNGRIAMLGFIALIIELITGHGFLHMIGLLQ
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKQ7_SCHPO
Sequence: MEENTAQKQSNATGLQRHVSGRWISNVPSYEGNEWSSEESESEDKESNLTSSENIGKNPERELNSDGTDRIIEEEEEEDDIENEASSFSEQSENENYDFSYPGTFVYRKAASSSHETLATKVVSADESARLWAEKRRFLLQKLGKDPNSKPIDYKSSMASSSTRSSQSSQVSAIQPQSQDDNRVSDIRQMENRRELNVKRRSVSSPAEDLAIRPLSFSRYKKAEEIPESLPPIKGRDSFSSVRELNESNVFARAPNKNRFSFASVAETGSGSNFSRATSSRSSKTRSVVYEPNHRHTSFFGDTLSNLSSSLNDKKSPNDDHAVLDSELMEQTLPDSAEAVEIANNVKEDIVSTANDDANELDNTSEKATLETSSKPVTEQAIEQSEVVQEVEEGDTNMTTNTILKPTDEIINKGYAYSITSSHSNHSNEKFEQIPSPDEKLSRTDIDTHVKQLQTTKSTDSLSIPFVESPQQNPEEELSDSLSNDFGIDAEKEKDENLSKPEHHPSITSVNSPFLYSPSKQPSGELDEENLKLRLQDSDVDDEVATIRSLKQNNATNSEVETVTNDPSFSQQPGTHSRILRNFDAISSIDSIPDSFSDSAVDLPVDSSKYTLVGKTQSNSNLLQDNAEKHISKSNLEKVDVKGDTSPNSVEQGIEPQAASVVGSPRSSLVSNNSLEEGALLKNSESLESIYGYLSEEPDPALTKLNTEDPFWTKGSSDDEHTIASVEQDVYPYKTSLPTIVEATTSHTESSNSKAPAIEETTTTKVEVVAAHDAVSISSNSSTHKSHSEPLNRDELEVAALSRGSLPEPPKPNKQIVVQEEDQRDTLSLKTSTTGLSSHSKSAENNSTQQSTTSPSINSGASADAVSSGISKKADNSETNLNYFATLDAFVKSPLMSFDGLGELGSTDQRYNFFNQKIQEYSAYDSGLDNWIQFCLEKDGEAPKEAPPPPRSEPVSTTTKLAKRITQPSLSPARSTVTITHNIATEAKKKSKSAANDILHLFKKKAKSEQSNAKSSSSSIKESKKMKTLFGKKLGFKS
What are the official names of this protein?
Uncharacterized protein C688.07c.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at the cell tip and the barrier septum.
Protein: HIS6_PSECP
Sequence: MAVAVRVIPCLDVDAGRVVKGVNFEGLRDAGDPVELAHRYDNAGADELTFLDVTASSGNRETTFDVVRRTAEEVFIPLCVGGGVRGVAEVDKLLRFGADKAAINTAAVARPDVIDEITRHFGSQVLVLSVDARRTRPGSKPTPSGFEVTTHGGRTGTGIDAIEWAKEAADRGVGEILLNSIDADGTKDGFDLEMIRMVRAAVKVPLIASGGAGEPAHFPPAVAAGADAVLAASIFHWGPNDMMHQVKDAIRNAGFEVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADH4_RAT
Sequence: MGTQGKVITCKAAIAWKTDSPLCIEEIEVSPPKAHEVRIKVIATCVCPTDINATNPKKKALFPVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKKCKLCLSPLTNLCGKLRNFKYPTIDQELMEDRTSRFTSKERSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGFTSGYGAAINTAKVTPGSACAVFGLGCVGLSAVIGCKIAGASRIIAIDINSEKFPKAKALGATDCLNPRDLDKPVQDVITELTGGGVDFSLDCAGTAQTLKAAVDCTVVGWGSCTVVGAKVDEMNISTVDMILGRSVKGTFFGGWKSVDSVPNLVTDYKNKKFDLDLLVTHALPFDKINDAIDLMNQGKSIRTILTF
What is the function of this protein?
Catalyzes the NAD-dependent oxidation of either all-trans-retinol or 9-cis-retinol (PubMed:17279314).  Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate (By similarity).  Also catalyzes the reduction of benzoquinones (By similarity).
What are the official names of this protein?
All-trans-retinol dehydrogenase [NAD(+)] ADH4, Alcohol dehydrogenase 2, Alcohol dehydrogenase 4, Alcohol dehydrogenase class II, Alcohol dehydrogenase II.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYR_SHV21
Sequence: MVQALNCIVAVAQNMGIGKQGNLPWPRLMNDFKHFQRMTTTSSVPDKQNLVIMGKKTWFSIPEKNRPLKGRINVVLSKELKELPHRAHFLAKSLDDALKLTEQPELANKVDMVWIIGGSSVYKEAMSYPCDLKLFVTRIMQDFECDTFFPEFDLEKYKLLIEYPSVLSNVQEEKSIKYKFEVYEKNH
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Viral dihydrofolate reductase, vDHFR.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: ATPD_COXBR
Sequence: MALHLTLARPYAKAAFADGQKANQLEAWLAVFTAFSKIIKNKEVARQIINPKFSDKEIKTLLFDLIQTIEPESTKQLKDKIDHFLQLLIDEKRLMILPDIALVYQQLLNKYQGIIEASVTYVFPLNDEHRQQIQKQLEKRFNAEVKLKMIKDESLLGGVIIRAGNWVMDGSIKGKLTRLAENLKG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FDHD_SALPC
Sequence: MNNILFEEVLNVTDFTTSRQLTLWKREDLQSPQLDDVAEEVPVALVYNGISHVVMMASPKDLTHFAMGFSLSEGIIDSPREIYGMDVVPSCNGLEVQIDLSSRRFMGLKARRRALAGRTGCGVCGVEQLNDIGKPVQPLPFSQTFNLGNLDRALKHLNDFQPTGKLTGCTHAAAWVMPSGELAGGHEDVGRHVALDKLLGRRATEGEEWRQGAALVSSRASYEMVQKSAMCGVEILFAVSAATTLAVDVAERCNLTLVGFCKPGRATIYTHPQRLIAD
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF123_ASFB7
Sequence: MPSTGTLVIIFAIVLILCIMLLFFYKTVEAEKPGVLPPPIPPPTPPPSKKKYDHNEYMEKTDLEPEVKKNHRKWANEAEHLISSSVKGLENLDETAFLANHKGHGFRTFEHAKSLFKEFLKKY
What are the official names of this protein?
Uncharacterized protein CP123L, pCP123L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus CP123L family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein. Virion.
Protein: THIG_NITWN
Sequence: MVSFYDREFSSRLLIGTALYPSPKIMQDAIRAAGSQIVTVSLRRETAGGKTGDAFWSLIRELDVTVLPNTAGCKTVREAVTTAKLARELFGTSWIKLEVIADNDTLQPDVVGLVEAAAILIRDGFDVFPYCTEDLGVAMRLVEAGCKVVMPWAAPIGSAKGITNRDALKLLRERLPDVTLVVDAGLGAPSHAAQACELGYDAVLLNTAVAKAADPVVMAGAFRLAVEAGRNAYEAGLMEARDFASPSTPVVGTPFWHAVS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AA2BR_RABIT
Sequence: MQLETQDALYVALELAIAALSVAGNVLVCAAVGTSSALQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAILVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATANCTEPRDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLAIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCVTLFQPAQAKDKPKWAMNTAILLSHANSVVNPIVYAYRNRDFRETFHKIISRYVLCQTDVKSGNGQSGAQPVLSMGL
What is the function of this protein?
Receptor for adenosine.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity).
What are the official names of this protein?
Adenosine receptor A2b.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RR2_PELHO
Sequence: MTKRSWNIRLEDMVAARVHLGHDIKKRNPRMAPYISAKLKDTDITNLKKTARFLSETCDLVFEAASKGKKFLIVGTKKEVANSVAQAARTAGCHYVNQKWLGGMLTNWSTTKKRLHKFRDLIRQQGRLNRLPKRDAAILKRQLFHLQKSLGGVKYMKELPDIVIILDQHGEFTALRECISLRIPTIGLIDTNCDPDLVDLPIPANDDSIPSIRFILNKLILAICKGRSRRTITSRPSHIKKKEKNR
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PUR7_FINM2
Sequence: MEKLYEGKAKEVYSTEKADEYIIRYKDDATAGNGEKKATIAGKGELNLAITTMIFEMLEKNGIKTHYIETINNTDMRVKKVTIMPLEVIVRNITAGSFAKRYGVEEGRVLNQPTFELSYKDDDLGDPLMCEDHAIALGVITKEEYDYLRKETLKINELLKEFFLKINLKLVDFKIEFGKTDDGQILLADEISPDTCRLWDKDTNKKLDKDIFRRDLGDLTEGYKEVLNRMRG
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: HUPG_BRADU
Sequence: MEFQVGKHDLTRHGLNEVDAATVDHFLGAADEAGAIAVLLSAGDPNRFPEATDVAVVLPELIAAFGGRLRGAVIARGDESALGQRFGVRVQPTLIFVAKGETLGLIAKIQDWSVYVDRITKLIDRPRGQSAAVAVTIVPQHRTQGVEL
What are the official names of this protein?
Hydrogenase expression/formation protein HupG.
What is the protein family that this protein belongs to?
Belongs to the HupG/HyaE family.
Protein: LEU1_METI4
Sequence: MEMTANRLIVFDTTLRDGEQCPGASMTSRQKLEVAKQLARLGVDVIEAGFPVISQGDFESVSEIAAQVKGPKICGLARCLPKDIEAAAEALKAAADAARIHVFLATSQIHRRFKLAKDEEEIVRIAVEGVRLAKRYVQDVEFSAEDASRTEPEFLAKIIQKVIEAGATTVNIPDTVGYAVPEEFASLIRYLFDHVQDIDKVVVSVHCHNDLGLAVSNSLAAIKAGARQVEGTINGIGERAGNAALEEIIMALHTRPDAFGKIETGIQLKEILRTSRLVSRMSGLAVQRNKAVVGENAFAHAAGIHQDGILKKRETYEIIDPKIIGWEQSELPLTKHSGRAALENRLKILGFELEKEEIDNIFSQFKQIGDKKKFIYDDDLVSLVEGQISRIKETYELEYVAVTVCSGGIPMATIKLRHGEEVLVDASTGDGAVDAAMKAVDRITGQHGHLVEYEVKSVTEGKDAIGEVTVKVNFDSKKLVTAKAASTDVIEASIKAYLNAVNKALL
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: RL10_STRZP
Sequence: MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRRELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSKNAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAESKEDAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: DPCKG_SULIY
Sequence: MEIRDNNKVNLCFAFDNLRKELSRPYGILFTNNKLFLDFVSKSIQQGFKVITVGDYVSRVLEENGIIPFLEVIDGKTKRSIPQRTIVKNKEYKVTNEAGKIRFEIFEIMENILKDRDGGVVFVNGEEDLLVIPVTLSADNGDIVIYGQPNAGAVVIIVNEMIRWRVRDILEKAVVKEC
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: 3S11_NAJHH
Sequence: LECHNQQSSQPPTTKTCPGETNCYKKRWRDHRGSITERGCGCPSVKKGIEINCCTTDKCNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin 1, Toxin CM-6.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPF_BACAN
Sequence: MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: HIS6_METAR
Sequence: MLTRRIIPCLDVTLGPNGGCVVKGVEFVNLRSAGDPVELAKRYNDQGADELVFLDITASHEGRATMIDVIERTASEVFIPMTVGGGIKTIEEIRALLRAGADKITINTTAVKDPEFIRKASDIFGSQCIVTAIDCRSNTNIDDPNARNIVRRRDGTPAWYEVVIYGGRKATGIDAIEWAKTIEELGSGEIMLTSMDADGTKDGYDLYITKAIGEAVRIPVIASGGAGTIEHMYDAFKIANADAALAASIFHFGEYTIGQAKDYLRQRGIPVRP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.