PharMolix/UniProtQA huggingface dataset:
Protein: HV551_HUMAN
Sequence: MGSTAILALLLAVLQGVCAEVQLVQSGAEVKKPGESLKISCKGSGYSFTSYWIGWVRQMPGKGLEWMGIIYPGDSDTRYSPSFQGQVTISADKSISTAYLQWSSLKASDTAMYYCAR
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 5-51.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: NIKR_HELPG
Sequence: MDTPNKDDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGGLRGVKFAKLTKASSFEHNE
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: LON_MESM1
Sequence: MKYPFMATRGVITFIGNSSTIEVGRPLSLAAIDLAKSDFENKLVLIPQKNIKQNEIEFEKDLENVGILTKIKSIKILSNGNRKIIVEGVERIKLDSIEKDKNNNDIIANLSLYPVLKNENGSSETIIEKMQTSLNNIIESNLPLVANQELSKHESSERYTYILAHYLTMPFEKKFEIFAKKSLTEMLELIFSFLVELKNIQKLDVDLDKDIKKNLDSQQREYLLRERLKVIQKKLGDDENDEEEIEEKLNSKYGKEQYPEEVIKTIKNEKRRLKNMMSSSPEANTSRTYIEWLTNLPWRKVSVDKTNLVKSKEILDSYHYGLKEVKERIIEFLAVMINNNKKHPEDEKTKIQIPNSDYEINKNLFTKKNASDDTYSYKSSNNVPILALVGPPGTGKTSLAKAIAETLDRKFIKISLGGVKDEAEIRGHRRTYVGALPGKIIQAIKKAGVSNPVILLDEIDKMSSDYKGDPTSAMLEVLDPEQNVNFQDHYIELEYDLSKVLFIATANYYQNISAPLLDRVEIIELSSYTSLEKIRIARDYLIKKVLEQNSLEESQFKISDESLDFLIKHYTLEAGVRNLQRALDKLARKIVVKSLENKLEKDFVITSEEIVNLLGVIKYTDDFKENYERIGAVNGLAYTQYGGSTLSIEVTTFPNSKGGIKLTGQLKEVMQESAQIALAFVRSNAKKYEIDFNFEANQIHIHVPEGAVPKDGPSAGVTFTTAIISALKQIPVSHKVGMTGEITLRGKVLPIGGLKEKSLAAHKLGIKTVFIPNENNRNLVEVADEVKESIEFISVSDYDEIFENLFGKLSDNKKITSNSKIPKKDISKANPTH
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
Protein: YQGF_KLEP3
Sequence: MSGTFLGFDFGTKSIGVAVGQRITATARPLPALKAQDGKPDWNVIEKLLKEWQPEAVIVGLPLNMDGTEQPLTARARNFANKIHGRFGVAIVLHDERLSTVEARAGLFEHGGYRALNKGSVDSASAVVILESYFEQSF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAGR1_BOVIN
Sequence: MSLVRGHGDIAATTAAPLSEEGEVTSGLQALAVEDTGGPSASADQAEEEGEGGREEAEHEGSGAEEVQGEAPSPEGEERAKGESEDWCVPCSDEEVELPADGQSWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPTTPKDSLIDRRRTPGSSARSQKREARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEDASPASPPLRSSGSLFPRQRKY
What is the function of this protein?
Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation.  However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex.  Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1:PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex.  However, its function in DNA damage has been questioned.  During immunoglobulin class switching in activated B-cells is involved in transcription regulation of downstream switch regions at the immunoglobulin heavy-chain (Igh) locus independently of the MLL2/MLL3 complex.  Involved in both estrogen receptor-regulated gene transcription and estrogen-stimulated G1/S cell-cycle transition.  Acts as transcriptional cofactor for nuclear hormone receptors.  Inhibits the induction properties of several steroid receptors such as NR3C1, AR and PPARG; the mechanism of inhibition appears to be gene-dependent.
What are the official names of this protein?
PAXIP1-associated glutamate-rich protein 1, PAXIP1-associated protein 1, PTIP-associated protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1265_RICBR
Sequence: MKLFPRTLLKILVVSFILNFGVTSKSYADDTLDTIVNTLQNLTCETQGVGDLLRTEFSQTCIVAPFFTFAIMNLVSPVLYMNTFLKLRINDNELFGTQFPGGQCTRENRADPNDLKLTFGLCSNLKLAGVRAKAVVDSALAIAKAVLTGNDPWDDIKEAWKNNKADYYNIYTQKPEDSGTMWDLGVPIFWKVVQDNDRICVGTYGFTGVVPVGCKYIKEPFPKSMYNSFMDVNDTNFIDDPNNKAVDPLALVSCSAAGGGCYQKAYNASRTAVVMTSPLIECIRQMIARLLISEDVCSFDDVNAVVNSASRQTSALFQFQVGMYRIVTAFLTLYVMLFGAKILLAGQVPPKNEYINFILKIIFVTYFSIGLNITPGSTSPYDRMDGMIQWAFPFLLNGINGLASWVMNAAPSGLCKFNGPDISYDNSVAYIALWDALDCRVAHYLGLDMLSTLLVENTYKSHNFANFDFFSFSAPPYIYLLIPAIISGNMMLVSLALAYPLLVISVAAFMVNATVMCMVSIVILGILAPLFVPMFLFDYTRGYFDSWVKLMISFLLQPMVVVTFMITMFSVYDFGFYGKCQYQSKLIHNSIEGALQGQTFKRDVLVFFVDNDWTKYSKEDAESCQNSLGYMLNNPISTAFNFAKDSVEQIVGSKPNQTCDPKAADADTKCNPKPGDSSTSSFLSKFQFLSGVILGPGMFFVSPKLLFEKIKDILLALVTACFTLYLMYNFSSQLANFAADMTEGVALSSVAIKPQAVFKAAMAALAAAGNATKGLDQFATKGGGGGDLLSTKGGRAGDLVKGSGGGGGSEGGDSFTSGGLRETSSTAATPSSALSSVGKSVGGTATPSSASEEMLDTSFSNRKPIEAPVSQPTTVSTQIDTAIKTEPPKVSAAEVVRNTAEDKLEDLSSKLNVTKEIKEAVPESQKEEPKEPRVKHTTEVEPELNLDENLGVTRTIRGLDKDRKFTEQESHELKIGEAGYVKQEMRNAQIRDRRAAFEKETEELYRSVGGRAKDKATERNDGTIENRSKKIDSGSDENP
What are the official names of this protein?
Uncharacterized protein RBE_1265.
What is the protein family that this protein belongs to?
Belongs to the TrbL/VirB6 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NEOK_STRFR
Sequence: MAEAPAGRALFEIYDEGFDSPSWGGVETALWHLSRSLREAGTEAEFYRSSEGADLDALAARVERDRVDAVFPLVESDLFEGAAWRRLPALHARTVRVWHDVSRLSADLSAPPPCPVHARVPALPGAPVAEGCPARGAHPEGPMREVFLGEWPWTRCFPRRSVIPWAADHVPAKDLCDPSGPVVLQLGKIDTVDAERCLRRLTGAGVALRVVFATWSRRGREARELVRAHQGAGRRVEVLDAYDIRTDWERVFGGASLFLLPSVFHETYNFAAAEAVQLGVPVAALGEGGNLPRFASLTAPTPDALVDRLLAGGGAVAPRPRPAAGWRDVAARYAEVIREHPAAGAGPAVPAGAGEGRGGREEEHGG
What is the function of this protein?
Glycosyltransferase involved in the biosynthesis of neomycin by mediating glycosylation of ribostamycin with UDP-GlcNAc as a sugar donor to generate 2'''-acetyl-6'''-hydroxyneomycin C.
What are the official names of this protein?
UDP-GlcNAc:ribostamycin N-acetylglucosaminyltransferase, Neomycin biosynthesis protein 15, Neo-15, Neomycin biosynthesis protein K.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: SYI_SHEHH
Sequence: MSDYKSTLNLPETEFPMRGNLANREPEMLKSWNENGLYQQIRESRKDAKPFILHDGPPYANGDIHIGHSVNKILKDIIIKSKTMSGFDAPYIPGWDCHGLPIELKVEQKVGKPGHKVTAAEFRQKCREYAAKQVDGQREDFIRLGVFADWQNPYLTMDFSTEANIVRSLSKVIENGHLHKGVKPVHWCTDCGSALAEAEVEYEDKMSPAIDVAFTAVDKSALLAKFGLADYAHNISMVIWTTTPWTLPANRALAVAANVEYTLVEMVKDGQTQALVLATDLYESCIERFGAESHTVLGTVAGSDLELLRFNHPFYDFDVPVILGDHVTVDSGTGVVHTAPGHGQDDFVVGQKYGLEVANPVGDNGVYKPDTEIFAGLHVFKANKNVVELLEEKGALLSHVQIKHSYPHCWRHKTPIIFRATPQWFISMDQKGLRTQAISEIEQTKWIPDWGQSRIEKMVENRPDWCISRQRTWGVPITLFVHRETEELHPDSVSLMERVAARIEQQGIQAWWDLDASELLGDEADQYRKVTDTLDVWYDSGSTFSTVVAARPEFHGHDIDLYLEGSDQHRGWFMSSLMISTAMNGKAPYKQVLTHGFTVDGQGRKMSKSVGNVISPQHVTNKLGADILRLWVAATDYSGEMTVSDQILNRSADAYRRIRNTARFLLANINGFDPVSDMVAIEDMVALDRWVVRRAAALQQELLEAYDEYNFHLVTQKLMQFCSVELGSFYLDIIKDRQYTAKGDSNARRSCQSALYLISEAMVRWIAPILSFTADEIWKLLPGERGEYVFTETWYEGLKSITLESDLSDEYWDQLLAVRAEVNKVIENARREKQIGGSLEAEVTLFADDALSAVLEKLGDELRFVLLTSKTEVVALAAAPSDAIGTELASLKLSLKKSEAEKCERCWHHREDVGTVTEHPTLCVRCVTNIEGDGEVRQFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUB24_ARATH
Sequence: MDQEEEEIEIPNYFICPISLEIMKDPVTTVSGITYDRQNIVKWLEKVPSCPVTKQPLPLDSDLTPNHMLRRLIQHWCVENETRGVVRISTPRVPPGKLNVVEEIKNLKKFGQEALGREETLQKLEVLAMDGNNRRLMCECGVHKSLILFVVKCTSEDEDGRRRIKGLDESLRLLHLIGIPSNDAKTILMENDRVMESLTWVLHQEDFLSKAYTIVLLRNLTEYTSSHIVERLNPEIFKGIIGFLKDVVNSVNRTSPTVRETVQSSSRPSLGKTEPSKLDHSLVIKQAVTAALMILLETSSWSRNRSLLVDLGAVSELIELEISYTGEKRITELMLGVLSRLCCCANGRAEILAHRGGIAVVTKRLLRVSPAADDRAISILTTVSKFSPENMVVEEMVNVGTVEKLCSVLGMDCGLNLKEKAKEILKDHFDEWKKFPCIDITLLTKLLSISPKGPKI
What is the function of this protein?
E3 ubiquitin-protein ligase that acts as negative regulator of the immunity triggered by the pathogen-associated molecular patterns (PAMPs), in association with PUB22 and PUB23.
What are the official names of this protein?
E3 ubiquitin-protein ligase PUB24, Plant U-box protein 24, RING-type E3 ubiquitin transferase PUB24, U-box domain-containing protein 24.
Protein: NOEC_AZOC5
Sequence: MWNKEWAAKIPFMTYCEACRPHHWLKNGLLFVPVLICGRAEDLLQAPLWLAFMTFCSVASGIYVLNDLMDRAHDRRHPSKRHRPFASRKLSGLTGVWMCLVLIALGGVCAINCGERLFAITASYVALSVIYVGKVRGEYVLDLFVLSALYTTRILAGATAANIPVPASFLAFSAMAFVSLASIKRLNELTQLRRDGAPDLYGRGYELSDHSIVALICVSAGYAAVVFLELFVQMSSVAQGPAPIFVSNAMCVVVAYWISRAVVQAHRGDMRSDTLCYAVTDGSSLVCILGLALGLVFLMYCRSQSIG
What are the official names of this protein?
Nodulation protein NoeC.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COPA_ARCFU
Sequence: MVKDTYISSASKTPPMERTVRVTGMTCAMCVKSIETAVGSLEGVEEVRVNLATETAFIRFDEKRIDFETIKRVIEDLGYGVVDEQAAVSAEVEHLSRMKRKLYVAAFAGVLLLFLAHFISLPYEDFVQLLIALPAIFYSGSSIFKAAFSALRRRTLNMDVMYSMGVGAAFLASVLSTAGVLPREYSFYETSVLLLAFLLLGRTLEARAKSRTGEAIKKLVGLQAKTAVVIRDGKEIAVPVEEVAVGDIVIVRPGEKIPVDGVVVEGESYVDESMISGEPVPVLKSKGDEVFGATINNTGVLKIRATRVGGETLLAQIVKLVEDAMGSKPPIQRLADKVVAYFIPTVLLVAISAFIYWYFIAHAPLLFAFTTLIAVLVVACPCAFGLATPTALTVGMGKGAELGILIKNADALEVAEKVTAVIFDKTGTLTKGKPEVTDLVPLNGDERELLRLAAIAERRSEHPIAEAIVKKALEHGIELGEPEKVEVIAGEGVVADGILVGNKRLMEDFGVAVSNEVELALEKLEREAKTAVIVARNGRVEGIIAVSDTLKESAKPAVQELKRMGIKVGMITGDNWRSAEAISRELNLDLVIAEVLPHQKSEEVKKLQAKEVVAFVGDGINDAPALAQADLGIAVGSGSDVAVESGDIVLIRDDLRDVVAAIQLSRKTMSKIKQNIFWALIYNVILIPAAAGLLYPIFGVVFRPEFAGLAMAMSSVSVVANSLLLRNYVPPIRRGGDSVEKIVLELSGLSCHHCVARVKKALEEAGAKVEKVDLNEAVVAGNKEDVDKYIKAVEAAGYQAKLRS
What is the function of this protein?
Probably involved in copper and silver export.
What are the official names of this protein?
Probable copper-exporting P-type ATPase, Copper-exporting P-type ATPase A, Cu(+)-exporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1513_BACC1
Sequence: MAKIGVENSLTDVQQALQQQGHEVVTINSEHDAQGCDCCVVTGQDSNMMGIADTSIKGSVINAHGLTTDEICQQVESRI
What are the official names of this protein?
UPF0180 protein BCE_1513.
What is the protein family that this protein belongs to?
Belongs to the UPF0180 family.
Protein: NU5C_DAUCA
Sequence: MEQTYQYAWIIPFLPLPVPMLIGAGLLLFPSATKSLRRMWAFQSVFLLSIVMLFSINLSIQQINGSSIYQYVWSWIINNDFSLEFGYLIDPLTSIMSILITTIGIMVLIYSDNYMSYDQGYLRFFAYMSFFSTSMLGLVTSSNLIQIYIFWELVGMCSYLLIGFWFTRPVAANACQKAFVTNRVGDFGLLLGILGFYWITGSFEFRDLFKILNNLISNNEVNFLFVTFCAVLLFAGAVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLIPLFIVIPHIMNFISLVGVITILFGATFALAQKDIKRGLAYSTMSQLGYMMLALGMGSYRSALFHLITHAYSKALLFLGSGSVIHSMETLVGYSPNKSQNMVFMGGLTKHVPITKTSFLLGTLSLCGIPPLACFWSKDEILNDTWLYSPIFAIIAWFTAGLTAFYMFRIYLLTFEGHLNVHFQNYSGKKNTPFYSISLWGKENSKRINKNFSLLTMKNPEIFSFFSKKTYQIDQNARNITQPFITITRFGNKKFFLYPYESDNTMLFPILVLVLFTLFVGSLGIPFNHEGVRLDILSKWLTPSINLLHKNLNNSIGWYEFLKDALFSVSIAIFGIFIAFFLYKPVYSSLQNWDLINSFVKTGPKRILLDKIINGIYDWSYNRGYIDAFYARFFIGGIRGLAKLTSFFDRRVIDGITNGVGVLSFFLGEGIKSIGGGRISSYLFLYFFFVAILLLIINFLLI
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y7147_DICDI
Sequence: MFTLKENNPSLITIFFFFFSNNATTTTTTTTTTTTTTTTTTTTTTTTTATTTTTTF
What are the official names of this protein?
Putative uncharacterized protein DDB_G0275629.
What are the subcellular locations of this protein?
Secreted.
Protein: TAL_BORPE
Sequence: MPSQLEALRRHTVVVADTGDFEAMRALRPTDATTNPSLILKAVQQEAYRPLLVQTARAHQGASPAEITDRLLVAFGRQILDIVPGRVSTEVDARLSFDTRATVERARGLIALYQAAGVPRERVLIKIASTWEGIQAARVLQAEGIRCNLTLLFCLPQAAACADAGVQLISPFVGRIYDWHKKNAGAEWVEDARRGANDPGVQSVSRIYRYYKRFGIETEIMGASFRNVDQILALAGCDLLTISPELLTRLAQTEGEVPAALSPQAGHDDADAVRLDGGEVAFRTQLNEDAMASEKLSEGIRLFVADARKLDALIESHGAA
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCA_HYPBU
Sequence: MIVIDGSIGEGGGQILRTTLALAALLGKPVRIVNIRAKRPRPGLQRQHLTSVKAVAELASARVEGLELGSTTLVFIPRGLRSGRFYFNIGTAGSITLVLQALLPVTAFAPGPVEVEIVGGTDVPWSPPIDYVRFVLRKLLAMFGFEFEIIVKRRGHYPRGGGRVVLRVTQPPHVLKPVKLEERGKVLRVEGLSHAVRLPRHVAERQARSAEAVLRSKLPGVPISIDLEWYEPSRDPHLGPGSGVVVWAVAEHSVLGSDSLGAKGKPAEAVGREAAEKLLEDLATGTALDRHASDMLIPYAALACGESILGGARLTMHAWTNIEVVKMLVPGAEMEFIEGGKLNEKFKLRVKGICYKPSS
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADH1A_PONAB
Sequence: MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAQEVRIKMVAVGICGTDDHVVSGTMVTPLPAILGHEAAGIVESVGEGVTTVKPGDKVIPLAVPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRGKPIHHFLGISTFSQYTVVDENAVAKIDAASPLAKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYNKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAVLGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINDGFDLLHSGKSIRTILMF
What is the function of this protein?
Alcohol dehydrogenase.  Oxidizes primary as well as secondary alcohols.  Ethanol is a very poor substrate.
What are the official names of this protein?
Alcohol dehydrogenase 1A, Alcohol dehydrogenase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_CLOTE
Sequence: MKVILLKDVKKLGKKDDVVNVSDGYARNFLFPRKLALEAKESNLNLLNNKKEAERKQKLAELEEAQKLAEELKNQELILKVKSGDNGKLFGSITGKDISDELKKKFKLDIDRRKINVENIRQLGVYDVEIKLYPEVSTKIKVKIEDI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: UREG_NATPD
Sequence: MGHRDVATVGLGGPVGSGKTAMVKRLVPRLDAAGYNVGVIANDIMTQEDADRLRESFEGILPPDLVEGVETGACPHTGIREDPSMNIAAIDEFTESYPDLDVVLLESGGDNLAATFNPELADYFIFVISVAEGDDIPRKRGPGVTQADLLVVNKTDLAPHVDADLEVMRRDAETVRGDAPTCFTDCKAEEGIDGVVDHIEEGVLFA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METXS_BURMA
Sequence: MESIGVVAPHTMHFAEPLRLQSGSVLGNYQLVVETYGELNAARSNAVLVCHALNASHHVAGVYADDPRSTGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPMSIDPATGTPYGARFPVVTVEDWVHAQARVADAFGIERFAAVMGGSLGGMQALAWSLLYPERVAHCIDIASTPKLSAQNIAFNEVARSAILSDPDFHGGDYYAHGVKPRRGLRVARMIGHITYLSDDDMAEKFGRALRRADGALDAYNFNFDVEFEVESYLRYQGDKFADYFDANTYLLITRALDYFDPAKAFNGDLSAALAHTKAKYLIASFMTDWRFAPARSREIVKALLDNRRSVSYAEIDAPHGHDAFLLDDARYHNLVRAYYERIAEEVGA
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSTU2_ARATH
Sequence: MAKKEESVKLLGFWISPFSRRVEMALKLKGVPYEYLEEDLPKKSTLLLELNPVHKKVPVLVHNDKLLSESHVILEYIDQTWNNNPILPHDPYEKAMVRFWAKFVDEQILPVGFMPLVKAEKGIDVAIEEIREMLMFLEKEVTGKDFFGGKTIGFLDMVAGSMIPFCLARAWECLGIDMTPEDTFPELNRWIKNLNEVEIVRECIPPKEKHIERMKKIIERAKSTF
What is the function of this protein?
May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase U2, AtGSTU2, GST class-tau member 2, Glutathione S-transferase 20.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Tau family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RS5_ALKMQ
Sequence: MQFNKRIDANQLDMKEQVVDIRRVTKVVKGGRNFRFAALVVVGDENGHVGVGTGKAMEIPDAIRKGIQAAKKNLLLVPTVGTTVPHEVIGHFGAGNVLIMPAKEGTGIIAGGPVRAVLELAGIKDVRAKSLGTNNSRNMVSATMDGLRQLKRAEDVAKLRGKSVEELLG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RLMI_SHESA
Sequence: MAVRIKLKPGREKSLERRHPWVFSNGIHNVKGKPEAGETVDVVAHDGHWLGRGAWSPESQIQVRIWTFDREEEIDREFFKRRILRAQAGRDDLIREQGLTGYRLIAAESDGLPGITIDKYANVLVCQLLSMGADVWRDTIVDVLAELYPDCAIYERSDVDSRKKEGLASTMGLLHGTLPEMPVIIEENGIKIAVDVTKGHKTGFYLDQRDNRAMAARFVKGKSVLNCFCYTGTFGLYAANAGAASIENVDVSALALDTARLNMRVNGLNDDNVHYNEADVFKLLRQYRDEGKTFDVIVLDPPKFADNKSQLNGACRGYKDINMIALQLLNPGGVLLTFSCSGLMPADLFQKIVADAALDAKREIQFIERLSQASDHPIGSAFPEGFYLKGLVARVW
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_SHEFN
Sequence: MAITAAQVKELRDRTGAGMMDCKNALTETDGDIELAIDNMRKSGAAKAAKKAGNIAADGTILIKNGEGFAALLEVNCQTDFVAKDSNFLAFANAVLDVAAASKVSIEDLKAQFEETRVALVTKIGENINVRRVEYIDGANLASYRHGDRIGVVVAGEADEETLKHIAMHVAASKPDFVNPEDVPAELVEREQALQIEIAMNEGKPAEIAEKMVVGRMKKFTGEISLTGQAFIMEPKKTVGEVLKSKGATVTSFIRLEVGEGIEKKAEDFAAEVAAQIAATKKA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFCL_METVS
Sequence: MEEWVEKYRPKSLNDVAGHSKTKEALCYWIESFIRGNKQKPVLLFGPPGSGKTTMAHAIANDYNFDVIELNASDKRNKDVISQVVGTAATSKSLTGKRTLIVLDEVDGLSGNDDRGGVSEIIKVLKNAENPVILTANDVYKPALSSLRNSVTMVDAGSVHTNSIPPVLRKIALKEGFEIDEKVIKLISSHAGGDLRAAINDLQALLTGGSIEIEDAKNLPDRDSEKSIFDAIRIIMKTTHYDIATSATVDLKEELGTVSEWISENLPKEYLKYGDLAKGYDYLSKSDVFLGRVYRRQYFGLWRYASALMTAGTALSKEDKYRGFTRYSPPTVFTKLSRTKVAREKLKEILKKIGIKTHTSIKGARSTLDFLYVIFESNLQMATDLTLYYEFTKEEVEFLTNKKISKDIFSIIECEKTKKTDDKNLMKKDLEEDTFKEKTNEIMPVIPKRPKISDNQISEILTKDNNPKDDVKKASKKPESTSKKQATLDKFF
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: RS15_CITK8
Sequence: MSLSVEAKAKIVSEFGRGTNDSGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTALIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RNC2_ASPCL
Sequence: MLYNKLITIAALLVPALAAPQGLDVRDCDYTCGSHCYSASAVSDAQSAGYQLYSAGQSVGRSRYPHQYRNYEGFNFPVSGNYYEWPILSSGSTYNGGSPGADRVVFNDNDELAGLITHTGASGNGFVACSGW
What are the official names of this protein?
Guanyl-specific ribonuclease C2, RNase C-2.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease N1/T1 family.
What are the subcellular locations of this protein?
Secreted.