PharMolix/UniProtQA huggingface dataset:
Protein: SPPA_ECOLI
Sequence: MRTLWRFIAGFFKWTWRLLNFVREMVLNLFFIFLVLVGVGIWMQVSGGDSKETASRGALLLDISGVIVDKPDSSQRFSKLSRQLLGASSDRLQENSLFDIVNTIRQAKDDRNITGIVMDLKNFAGGDQPSMQYIGKALKEFRDSGKPVYAVGENYSQGQYYLASFANKIWLSPQGVVDLHGFATNGLYYKSLLDKLKVSTHVFRVGTYKSAVEPFIRDDMSPAAREADSRWIGELWQNYLNTVAANRQIPAEQVFPGAQGLLEGLTKTGGDTAKYALENKLVDALASSAEIEKALTKEFGWSKTDKNYRAISYYDYALKTPADTGDSIGVVFANGAIMDGEETQGNVGGDTTAAQIRDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAARAAGKPVVVSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGVHTDGVSTSPLADVSITRALPPEAQLMMQLSIENGYKRFITLVADARHSTPEQIDKIAQGHVWTGQDAKANGLVDSLGDFDDAVAKAAELAKVKQWHLEYYVDEPTFFDKVMDNMSGSVRAMLPDAFQAMLPAPLASVASTVKSESDKLAAFNDPQNRYAFCLTCANMR
What is the function of this protein?
Digests cleaved signal peptides in vitro, its in vivo function is unknown.  This activity is necessary to maintain proper secretion of mature proteins across the membrane.
What are the official names of this protein?
Protease 4, Endopeptidase IV, Protease IV, Signal peptide peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S49 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HEMA_I78A8
Sequence: MKTIIALSYIFCQVFAQNLPGNDNSTATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGRICDNPHRILDGKNCTLIDALLGDPHCDGFQNEKWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFFNEGFNWTGVTQNGGSYACKKGPDNSFFSRLNWLYKSESTYPVLNVTMPNNDNFDKLYIWGVHHPSTDKEQTNLYVQASGRVTVSTKRSQQTIIPNVGSRPWVRGLSSRISIYWTIVKPGDVLLINSNGNLIAPRGYFKIRTGKSSIMRSDAPIGTCSSECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGIFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIGSIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQKGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: YBFE_ECO57
Sequence: MAKEQTDRTTLDLFAHERRPGRPKTNPLSRDEQLRINKRNQLKRDKVRGLKRVELKLNAEAVEALNELAESRNMSRSELIEEMLMQQLAALRSQGIV
What are the official names of this protein?
Uncharacterized protein YbfE.
Protein: XRCC1_CRIGR
Sequence: MPEISLRHVVSGSSQDSTHCAENLLKADTYRKWRAATAGEKTISVVLQLEKEEQIHSIDIGNDGSAFVEVLVTRSAGGGGATAIEQDYEVLLVTSSFMSPSESRSGSNPNRVRMFGPDKLVRAAAEKRWDRVKIVCSQPYSKDSPYGLSFVRFHSPPDKDEAETPSQKGTVTKLGQFRVKEEDDGASSLKPGALFFSRINKTSSASARGPAGPSYAAATLQASNATSSASSVSKALGSSCKPQESPKGKRKLDLNLEDRRPASKPSAGPPTLKRPKLTVPSRSPAAAAASTPAQKAAPGKPREGTEPRGARAGPQELGKILQGVVVVLSGFQNPFRSELRDKALELGAKYRPDWTPDSTHLICAFANTPKYSQVLGLGGRIVRKEWVLDCYRLRRRLPSRRYLMAGLGSSSEDEEDDSPGESGEDEAPKLSRKRPQAKAKTQAAGPSSPQRPPTPKETKSPSPEPQDNSDTEGEQSEGQDNGAEDSGDTEDELRRVAEQREQRQPPAPGENGEDPYAGSTDENTDNEASTEADLPIPELPDFFQGKHFFLYGEFPGDERRKLIRYVTAFNGELEDYMSERVQFVITAQEWDPIFEEALMENPSLAFVRPRWIYSCNEKQKLLPHQLYGVVPQA
What is the function of this protein?
Scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes.  Negatively regulates ADP-ribosyltransferase activity of PARP1 during base-excision repair in order to prevent excessive PARP1 activity.  Recognizes and binds poly-ADP-ribose chains: specifically binds auto-poly-ADP-ribosylated PARP1, limiting its activity.
What are the official names of this protein?
DNA repair protein XRCC1, X-ray repair cross-complementing protein 1.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Moves from the nucleoli to the global nuclear chromatin upon DNA damage.
Protein: UXAC_ECO5E
Sequence: MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDPIDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGETLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMSGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLGEMVKNICFNNARDYFAIELN
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: RL30_LISIN
Sequence: MAKLEITLKRSLIGRPQPQRKTVQALGLGKTNSVVVKEDNPAIRGMITKVSHLVDVKEV
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: POT8_ARATH
Sequence: MDLERLSPRNPVKKESWWTVLTLAYQSLGVVYGDLATSPLYVYKSTFAEDITHSETNEEIFGVLSLIFWTLTLIPLVKYVFIVLRADDNGEGGTFALYSLLCRHARISSLPNFQLADEDLSEYKKNSGENPMRLKVPGWSLKNTLEKHKFLQNMLLVLALIGTCMVIGDGVLTPAISVFSAVSGLELSMSKQQHQYVEVPVVCAILILLFSLQHYGTHRLGFVFAPIVLAWLLCISTIGVYNIFHWNPHVYKALSPYYIYKFLKKTRKRGWMSLGGILLCITGSEAMFADLGHFTQLSIQIAFTFAVYPSLILAYMGQAAYLSKHHVLQSDYRIGFYVSVPEQIRWPVLAIAILAAVVGSQAIITGTFSIIKQCTSLGCFPKVKIVHTSSRMHGQIYIPEINWTLMLLCLAVTVGFRDTKHISNASGLAVITVMLVTTCLMSLVIVLCWRKSSLYALAFIFFFGTIEVLYFSASLIKFLEGAWVPVALSFIFLLIMYVWHYGTLKRYEFDVQNKVSINWLLTLFGSSNLGIVRVHGIGVINTELVSGIPAIFSHFITNLPAFHQVVVFLCVKSVPVPHVKPEERFLVGRVGPKEYRLYRCIARYGYRDVHKDDVEFENDLICSIAEFIRSDKPLNYSPDPENESGINERLTVVAASSSNLEGVQIYEDDGSDKQEPSSSSEVIMVAPSPRFKKRVRFVLPESARIDRSAEEELTELTEAREAGMAFIMGHSYVRAKSGSSVMKKIAINFGYDFLRRNSRGPCYGLSTPHASTLEVGMVYIV
What is the function of this protein?
Probable potassium transporter.
What are the official names of this protein?
Potassium transporter 8, AtHAK8, AtPOT8.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLGPB_MOUSE
Sequence: MYSEWRSLHLVIQSDQGHTSVLHSYPESVGREVANAVVRPLGQALGTSSVAGSESLLKTDKEVKWTMEVICYGLTLPLDGETVKYCVDVYTDWIMALVLPKDSIPLPIIKEPNLYVQSILKHLQNLFVPRQEQGSSQIRLCLQVLRAIQKLARESSIMARETWEVLLLFLLQINDILLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAVISSTPKFQEQFLNVSGMPQELSQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQSAAVNTTPPHNRRHRAVTVNKATMKTSTVTTAHTSKVQHQASSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDNSMTASFIQILLSYKSSIATQASMEFRRKGSQMSTDTMVSNPVFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSSVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVRSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIGCQMEMGGGENNLKSHSRTNSGISSASGGSTEPTTPDSERPAQALLRDYGSTDSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVMVDSGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNSEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEERHEKLRSGMAQQIAYEMHLEQQSEGELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNVESSRNVQPHFLEFLLSLGWSVDVGKHPGWTGHVSTSWSINSCDDGEGSEPDEITSSEDVGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNISDQDSDSNMDLMPGILKQPPLTLELVPNHTDSLNSSQRLSPSSRMKKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQEVGLKNCSS
What is the function of this protein?
Non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators for the Ras-like small GTPases RALA and RALB.
What are the official names of this protein?
Ral GTPase-activating protein subunit beta, p170.
Protein: RL5_BART1
Sequence: MAEERQIPRMKTHYFEVIRKALQEKFNYKNAMQIPRIDKIVINMGIGEATADSKKPSLAAEDLGLITGQKAVVTRARNSIATFKVREGMPLGAKVTLRKDRMFEFLDRLVTIALPRVRDFRGLNPKSFDGRGNFAMGIKEHIVFPEINYDKVDQIWGMDIIVCTTAKTDDEARELLRAFNFPFRS
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: AF10_MOUSE
Sequence: MVSSDRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHFSKLKKSKRGSNRSYEQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTAARFTNANFQEVSAHTSSGKDVSEARGSEGKGKKSSAHSSGQRGRKPGAGRNPGTAVSASSPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLRSDSYTHTQQPSSTKDVHKGESGSQEAAVNSFSSLVGHPVTSTVISQPKSFDNSPGELGSSSLPTAGYKRAQTSGIEEEAVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSVTSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHIPQQSSGHLQQVGALSPSAASSVTPAAATTQANTVSGSSLSQAPAHMYGSRLNQNPSMAVLIAQSESSQTDQDLGDNARSLGGRGSSPRGSLSPRSPVSNLQLRYDQPSNSSLETVPPVAASIEQLLERQWSEGQQFLLEQGTPGDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPAITTNPSPSHQMHTYTAQTAPPPDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQSSGVSGVQQVNGVTVGALASGMQTVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVIQTPVTISQNPAPLTHTSVPPNAAHPMPAAALTNSASGLGLLSDQQRQMFIQQQQFQQLLNSQQLTPEQHQAFLYQLMQQQHHPPELQQLQLPGPTQIPINNLLAGAQAPPLHTATTNPFLTIHGDSTSQKVTRLSDKTGPVAQEKS
What is the function of this protein?
Probably involved in transcriptional regulation.  Binds to cruciform DNA (By similarity).  In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (By similarity).
What are the official names of this protein?
Protein AF-10.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNT3_YEAST
Sequence: MLKSLKSRRLILKRLVTLLLSLFFSYLIFSASRNVTSSNKLNNHASERTAVESSAFNWIEKRQHQVRSENLMNRLSAYFLPFLSRSSHKERVLLRQLGNNEIAKSDKCRYIFEVLYKIDPDWDNAQTAKFYNVDGVDNTLASLLGERLRSYDYCFLSGQLDPTAIFANSTVNPHDLQNRMFPFLKKINEESKTVMWPIITDMTTGEAVPAPEVDMESSNFNGNFWSNWNRLSKGRGFVLTIAEKDVPLFLKQLKVMEFSKNELPFQIVSTGNELSAESIAKISETAKETEQRVYLVDCSTVLDTNFANTYISFFQNKWVATLFNTFEEYILLDADVVPFVGSDYFFDSPSYRESGILLFKDRVMENEQTFQYCIEMLNEVEPSAQERRFIGSRLVFDSSLPFSSETSEEASVYYNFFKKLRLHHVDSGLVVVNKLEKLNGLLMSFMLNLDGKLQRCVYGDKEIFWLGQLYAGQDYSINPVDGSIIGPVNEEPENDDGHKSGMYYICSTQIAHSDSKNRLLWVNGGLKTCKISNSAEDDFGREPEYFKSRYGDISKLKRIYDASLNVEGLIVPDVSVHPWMQIKECSNYMYCAYATGDGHTNSELDEGRLITFTEKELRYINDISRTWNAN
What is the function of this protein?
Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans.
What are the official names of this protein?
Alpha-1,3-mannosyltransferase MNT3.
What is the protein family that this protein belongs to?
Belongs to the MNN1/MNT family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: VISTA_MOUSE
Sequence: MGVPAVPEASSPRWGTLLLAIFLAASRGLVAAFKVTTPYSLYVCPEGQNATLTCRILGPVSKGHDVTIYKTWYLSSRGEVQMCKEHRPIRNFTLQHLQHHGSHLKANASHDQPQKHGLELASDHHGNFSITLRNVTPRDSGLYCCLVIELKNHHPEQRFYGSMELQVQAGKGSGSTCMASNEQDSDSITAAALATGACIVGILCLPLILLLVYKQRQVASHRRAQELVRMDSNTQGIENPGFETTPPFQGMPEAKTRPPLSYVAQRQPSESGRYLLSDPSTPLSPPGPGDVFFPSLDPVPDSPNSEAI
What is the function of this protein?
Immunoregulatory receptor which inhibits the T-cell response (PubMed:21383057, PubMed:24743150, PubMed:25267631).  May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (PubMed:20042595).  May stimulate MMP14-mediated MMP2 activation (By similarity).
What are the official names of this protein?
V-type immunoglobulin domain-containing suppressor of T-cell activation, Platelet receptor Gi24, V-set domain-containing immunoregulatory receptor, V-set immunoregulatory receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GCSPA_BACAC
Sequence: MLHRYLPMTEEDKKEMLQTIGVQTIDELFSDIPESVRFKGDLKIKEAKSEPELLKELSQMASKNANLKEYASFLGAGVYDHYAPVIVDHVISRSEFYTAYTPYQPEISQGELQAIFEFQTMICELTGMDVANSSMYDGGTALAEAAMLAAGHTRKKKILVSSAVHPESRAVLETYAKGQHLEVVEINHKDGVTDLDVLQSEVDDTVACVIVQYPNFFGQVEKLADIEKIVHQQKSLFIVSSNPLSLGALTPPGKFGADIVIGDAQPFGIPTQFGGPHCGYFATTKAFMRKIPGRLVGQTVDSDGKRGFVLTLQAREQHIRRDKATSNICSNQALNALAASVAMTALGKQGVKEMARQNISKAQYAKRQFEAKGFTVTFAGPFFNEFVVDCKRPVKEVNDALLQKNIIGGYDLGRDYKEHENHMLVAVTELRTKEEIDTLVNEMGAIQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: CYB_MONRE
Sequence: MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLAVQILTGLFLAMHYTSDTATAFNSVAHICRDVNYGWTLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVAALVMVHLLFLHETGSNNPTGIPSDPDMIPFHPYYTIKDILGFLIMLTALSALVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAVVPILHTSKQRSMMFRPLSQFLFWLLVAVLFTLTWIGGQPVEYPYVIIGQVASILYFMILLVLMPLVSIVENRLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COPE_SCHPO
Sequence: MFSWEASLSNELYFVRQYFYSGNYTKLFEIDTTSMSEKGLELTEIYMARAKLALGESLESIQSILTQKTPGSAAILALAGEGNMELIIDQHGNSDSVVQTLGAIFQIKNGSFDDAMDLLKKSVENLEAVALQVYIHLREHKIEAAEQTLKQALDWADEEIVLQLAQSWIKIVSGGVESYNDAFYVFEELNGTDSNPMTLTGMACADICLLRPEEALSSLKTALDSQPNYEEALSNMTTAITDLGPDAPSQAKNILSSFTNSSTLKLNDHLNEKAQEFDTFSTQFLSTA
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Probable coatomer subunit epsilon, Epsilon-coat protein, Epsilon-COP.
What is the protein family that this protein belongs to?
Belongs to the COPE family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: TRPG_THET8
Sequence: MAANGAKGRKVMRVLVVDNYDSFTYNLVQYLGELGAEPIVWRNDRFRLEEVEALDPDRILISPGPCTPFEAGLSVPLVQRYAPRYPILGVCLGHQAIGAAFGGKVVPAPVLMHGKVSPIHHDGTGVFRGLDSPFPATRYHSLAVVEVPEALVVNAWAEEAGGRTVMGFRHRDYPTHGVQFHPESYLTEAGKLILKNFLEDPWTR
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 2, AS, ASII, Anthranilate synthase, GATase component, Anthranilate synthase, glutamine amidotransferase component.
Protein: DXR_CLOBL
Sequence: MKNITILGATGSIGTQTLDVIRREKEELKLVAISANKSYKKVIEIIKEFKPKYTVLMEENAFKIVEDFCIDNKIDTKVLKGMEGMIYISTLEEVNTVVTSVVGMIGLVPTIKAIESGKDIALANKETLVVAGELVISKAKEHNVNILPVDSEHGAIFQCLRGNKKEEVKNIIVTASGGPFRGKKKEELIDVKPEHALKHPKWNMGRKISIDSATLMNKGLEVIEAHFLFGVDYENIKVVVHPQSIVHSMVEYKDGSVIAQMATPDMKLPIQYALNYPNRKESQIEPLDFYKISNLTFEKPDMDTFLPLKLAYEAGKKGGVMPAILNGANEVAVDLFLKGKIEFLQIGDLLQECMNKFYKSMEATLENVISVDKEVREYLGKKYDI
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: PWP1_HUMAN
Sequence: MNRSRQVTCVAWVRCGVAKETPDKVELSKEEVKRLIAEAKEKLQEEGGGSDEEETGSPSEDGMQSARTQARPREPLEDGDPEDDRTLDDDELAEYDLDKYDEEGDPDAETLGESLLGLTVYGSNDQDPYVTLKDTEQYEREDFLIKPSDNLIVCGRAEQDQCNLEVHVYNQEEDSFYVHHDILLSAYPLSVEWLNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVWDISTVSSVNEAFGRRERLVLGSARNSSISGPFGSRSSDTPMES
What is the function of this protein?
Chromatin-associated factor that regulates transcription (PubMed:29065309).  Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription (PubMed:29065309).  Regulates the epigenetic status of rDNA (PubMed:29065309).
What are the official names of this protein?
Periodic tryptophan protein 1 homolog, Keratinocyte protein IEF SSP 9502.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PWP1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Chromosome. Note=Associates with chromatin regions of rDNA.
Protein: BAMA_HELPY
Sequence: MKKLILSSLVFACINTSVEALENDGSKPNDLTSPKEASQESQKNEAPKNEVQRNEAQKETPQSNQTPKEMKVKSISYVGLSYMSDMLANEIVKIRVGDIVDSKKIDTAVLALFNQGYFKDVYATFEGGILEFHFDEKARIAGVEIKGYGTEKEKDGLKSQMGIKKGDTFDEQKLEHAKTALKTALEGQGYYGSVVEVRTEKVSEGALLIVFDVNRGDSIYIKQSIYEGSAKLKRRMIESLSANKQRDFMGWMWGLNDGKLRLDQLEYDSMRIQDVYMRRGYLDAHISSPFLKTDFSTHDAKLHYKVKEGIQYRISDILIEIDNPVVPLKTLEKALKVKRKDVFNIEHLRADAQILKTEIADKGYAFAVVKPDLDKDEKNGLVKVIYRIEVGDMVYINDVIISGNQRTSDRIIRRELLLGPKDKYNLTKLRNSENSLRRLGFFSKVKIEEKRVNSSLMDLLVSVEEGRTGQLQFGLGYGSYGGLMLNGSVSERNLFGTGQSMSLYANIATGGGRSYPGMPKGAGRMFAGNLSLTNPRIFDSWYSSTINLYADYRISYQYIQQGGGFGVNVGRMLGNRTHVSLGYNLNVTKLLGFSSPLYNRYYSSVNEVVSPRQCSTPASVIINRLSGGKTPLQPESCSSPGAITTSPEIRGIWDRDYHTPITSSFTLDVSYDNTDDYYFPRNGVIFSSYATMSGLPSSGTLNSWNGLGGNVRNTKVYGKFAAYHHLQKYLLIDLIARFKTQGGYIFRYNTDDYLPLNSTFYMGGVTTVRGFRNGSVTPKDEFGLWLGGDGIFTASTELSYGVLKAAKMRLAWFFDFGFLTFKTPTRGSFFYNAPVTTANFKDYGVIGAGFERATWRASTGLQIEWISPMGPLVLIFPIAFFNQWGDGNGKKCKGLCFNPNMDDYTQHFEFSMGTRF
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: EF1A_WHEAT
Sequence: MGKEKTHINIVVIGHVDSGKSTTTGHLIYKLGGIDKRVIERFEKEAAEMNKRSFKYAWVLDKLKAERERGITIDIALWKFETTKYYCTVIDAPGHRDFIKNMITGTSQADCAVLIIDSTTGGFEAGISKDGQTREHALLAFTLGVKQMICCCNKMDATTPKYSKARYEEIVKEVSSYLKKVGYNPDKVPFVPISGFEGDNMIERSTNLDWYKGPTLLEALDQINEPKRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFGPTGLTTEVKSVEMHHESLLEALPGDNVGFNVKNVAVKDLKRGFVASNSKDDPAKEAANFTSQVIIMNHPGQIGNGYAPVLDCHTSHIAVKFAELVTKIDRRSGKELEALPKFLKNGDAGIVKMIPTKPMVVETFATYPPLGRFAVRDMRQTVAVGVIKGVEKKDPTGAKVTKAAIKKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADEC4_RHIME
Sequence: MSDVREFIRAASGGESKATVAVCGGRLVNVVSEEIYQADVAIYRDRIIAVGDISEYIGPQTEIIDAADRYLTPGMIDGHLHVECSKLSLTSFAKAVLPLGTTSIVSGLDQIIVVGGPDAAREFLDEVRQTPLKVFWGAPCKTPYTMPRSTVGHYFSPKDHRDTHHWPECVGIWETVREFIQEEDEDVLQAIEIGQANRLPVLGCCPMTRGARLNGYMQSGVRADHESYTPEEMLEKLRAGMHVVVRESSISHFLSDNLRIVTEMGVKALRRISFCTDDVVASDILSRGHLDNMVRMAMAMGISPMAAIQMATINGAEALRIDHKVGSISPGRTADILIVNDLRDFRIEAVVANGTVAARDGRMVVKLVPPQRSAGLLRSVKTTPVTAADIAVPFTGTTPFAEVLAIAVTPEKVFVRTRRDVRLPVVDGKILADASQNVQYVTVVERYGKTLNRPVAFVSGFNLKSGAIASSTAPDDNNIICIGADPQDMAIAINHLVANNGGQVVVDKGEVVEFLHLPIGGIVSDIDPAEMAAFELRLDEAARRLGCDLPWPFMYMFVLQITAIPDYAMTDLGVVDCVNLRIISPLAPDGPAKANTLAAE
What are the official names of this protein?
Adenine deaminase 4, Adenase 4, Adenine aminase 4.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: CBY3_MOUSE
Sequence: MADSKMKWGQAWDSSLGTATTSSSSATGSPSPFQNIRVPDTRAPRVAHTTFTLEAFECLAASQAGRLWKQVRQFWVDHFSRRFSPRRPPLRHISSMSTFYLLDHRTRQAELGLNYGEPRTRLSDEAFVFRGGRWTPEGKRASARTPLPSSTIPAWKPQVQPIKSQVLLEENNYLKLQQELLMDMLTETTARMQLLEKKVDADNNPAAPARSWKRKMPKQRGAGVLIIQPRALESR
What are the official names of this protein?
Protein chibby homolog 3.
What is the protein family that this protein belongs to?
Belongs to the chibby family.
Protein: ADEC_FLAPJ
Sequence: MQIQGQIVDIENKRIYSGEITIQNGKIISIIEKNHEVKNYILPGFIDAHIHIESSMLVPSEFAKIAVLHGTVATISDPHEIANVLGKKGVYYMIENGKQVPLKFHFGAPSCVPATAFETAGAIIDSEEIKELMASPDIYYLSEMMNYPGVLFDDDEVLKKIAWAKHFNKPIDGHAPGLRGEPIKKYISAGITTDHECFTYSEAQEKLSLGMKVIIREGSAAKNFEALIDLLPANYENMMFCSDDKHPDDLILGHINLLCARAVAKGIDVFKILQVACVNPVHHYKMKVGLLKKNDAADFIVVEDLVNFKVNKTYINGELVAENGQSFVENINFETPNNFNITKKKISDFEIPSLAEKIRVIEALEGQLITNEIHHNSFIKNGKLVSDIENDILKMAVVNRYQNTTPAIAFIKNFGLKKGAIASSVAHDCHNIVVVGTSDEEICNAVNLIIKNTGGICAVNGTQNKSLALPVAGIMSDKDAWETGKLYQEIDAMAKDLGSTLKAPFMTLSFMALLVIPDLKLSDKGLFSGNTFSFVDLNVE
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.