PharMolix/UniProtQA huggingface dataset:
Protein: SYV_BACCZ
Sequence: MSNTEKNLPTKYDHMSVEEGLYQWWLEGKYFEATGDEKKQPYTIVIPPPNVTGKLHLGHAWDTTLQDILTRTKRMQGYDVLWLPGMDHAGIATQAKVEGKLREEGISRYDLGREKFLEKAWEWKEEYASHIRQQWGKVGLGLDYSRERFTLDEGLSDAVNKVFVQLYEKGLIYRGEYIINWDPATRTALSDIEVIHKEVQGAFYHMNYPLTDGSGHIRLATTRPETMLGDTAVAVHPEDDRYKHLIGKTVTLPIVGREIPIIADEYVEKDFGTGVVKITPAHDPNDFEVGNRHDLPRILVMNEDGSMNEKAGKYNGMDRFECRKALVKDLQEAGVLVEIEPHMHSVGHSERSGAVVEPYLSTQWFVKMAPLAEKAVALQQKDEEKVTFVPERFENTYLRWMENIHDWCISRQLWWGHRIPAWYHKETGEVYVGTEAPADIENWNQDNDVLDTWFSSALWPFSTLGWPNEDAADFKRYYSTDALVTGYDIIFFWVSRMIFQGLEFTGERPFKDVLIHGLVRDEQGRKMSKSLGNGIDPMEVIEKYGADAMRFFLSTGSAPGQDLRFSMEKVESTWNFINKIWNASRFVLMNMDDMKYEEIDLTGEKSVADKWILTRLNETIESVTRNMDKYEFGEAGRSLYNFIWDDFCDWYIEMAKLPLYGEDEAAKKTTRSILAYVLDQTMRLLHPFMPFVTEKIWQHLPHEGESITVAAWPTVREDLQDTEAAAEMHLLVDIIRSVRNIRAEVNTPMSKKVQMQIKAKDEAVLAQLTKNSSYIERFCNPSELTIQTDLQAPEKAMTAIVTGAELFLPLADLINLDEERARLEKELEKFDKEVERVQKKLSNQGFVAKAPAAVIEGERAKEQDYLEKREAVRQRLADLEK
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_AGRFC
Sequence: MAKLYFNYSTMNAGKSTMLLQASYNYQERGMRTLIFTAAFDDRAGVGRVASRIGLSSEARTFDENTDLFAEVAALHAQAPVACVFVDEANFLSEHHVWQLANIADRLNIPVMTYGLRTDFQGKLFPASKELLAIADELREIRTICHCGRKATMVARFDSEGKVVTEGAQIEVGGNGKYVSFCRRHWVETFNCS
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOCK6_MOUSE
Sequence: MAASERRAFAHKINRTVAAEVRKQVSRERSGSPHSSRRSSSSLGVPLTEVIEPLDFEDVLLSRPPEVEPGPLRDLIEFPVDDLELLKQPRECRTTESGVPEDGQLDAQVRAAVEMYSEDWVIVRRRYQHLSTAYSPITTETQREWQKGLTCQVFEQDTPGDERTGPEDVDDPQHCSGSPEDTPRSSGASGIFSLRNLAADSLLPTLLEQAAPEDVDRRNEALRRQHRAPTLLTLYPAPDEDEAVERCSRPEPPREHFGQRILVKCLSLKFEIEIEPIFGTLALYDVREKKKISENFYFDLNSDSVKGLLRAHGTHPAISTLARSAIFSVTYPSPDIFLVVKLEKVLQQGDISECCEPYMVMKEADTAKNKEKLEKLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSRPQDRDSDSEGERRPTWAERRRRGPQDRGYSGDDACSFSSFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTAQLKLDISPAPENLHFCLSPDLLHVKPYPDPRGRPTKEILEFPAREVYAPHSCYRNLLFVYPHSLNFSSRQGSVRNLAVRIQYMAGEDQSQALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYEEFKLRLPACVTENHHLFFTFYHVSCQPRPGTALETPVGFTWIPLLQHGRLRTGPFCLPVSVDQPPPSYSVLTPDVALPGMRWVDGHKGVFSVELTAVSSVHPQDPHLDKFFTLVHVLEEGIFPFRLKETVLSEGTMEQELRASLAALRLASPEPLVAFSHLVLDKLVRLVVRPPIICGQMVNLGRGAFEAMAHVASLVHRNLEAVQDSRGHCPLLASYVHYAFRLPGGDLSLPGEAPPATVQAATLARGSGRPASLYLARSKSISSSNPDLAVVPGSVDDEVSRILASKGVDRSHSWVNSAYAPGGSKAVLRRVPPYCGADPRQLLHEELALQWVVSGSAVRELVLQHAWFFFQLMVKSMELHLLLGQRLDTPRKLRFPGRFLDDIAALVASVGLEVITRVHKDMKLAERLNASLAFFLSDLLSIADRGYIFSLVRAHYKQVATRLQSAPNPTALLTLRMDFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQSSTFSSQAPDPKVTSMFELSGPFRQQHFLSGLLLTELALALDPEAEGASLLHKKAISAVHSLLCSHDVDSRYAEATVKAKVAELYLPLLSLARDTLPQLHGFAEGSGQRSRLASMLDSDTEGEGDIGSTINPSVAMAIAGGPLAPGSRTSISQGPSTAARSGCPLSAESSRTLLVCVLWVLKNAEPTLLQRWAADLALPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKARLEEAILGTIGARQEMVRRSRERSPFGNQENVRWRKSATHWRQTSDRVDKTKDEMEHEALVDGNLATEASLVVLDTLETIVQTVMLSEARESILSAVLKVVLYSLGSAQSALFLQHGLATQRALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRMHASASLYLLMRQNFEIGHNFARVKMLVTMSLSSLVGTTQNFSEEHLRKSLKTILTYAEEDIGLRDSTFAEQVQDLMFNLHMILTDTVKMKEHQEDPEMLMDLMYRIARGYQGSPDLRLTWLQNMAGKHAELGNHAEAAQCMVHAAALVAEYLALLEDSRHLPVGCVSFQNVSSNVLEESAISDDILSPDEEGFCSGKNFTELGLVGLLEQAAGYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKIMHQSSGWERVFGTYFRVGFYGTRFGDLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKSKLDPQKAYIQITYVEPHFDTYELKDRVTYFDRNYGLRAFLFCTPFTPDGRAHGELAEQHKRKTLLSTEHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLSEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERHYSRLREALQPLLTQRLPQLLAPSSTSLRSSMNRSSFRKADL
What is the function of this protein?
Acts as guanine nucleotide exchange factor (GEF) for CDC42 and RAC1 small GTPases (By similarity).  Through its activation of CDC42 and RAC1, regulates neurite outgrowth in an vitro differentiation system.
What are the official names of this protein?
Dedicator of cytokinesis protein 6.
What is the protein family that this protein belongs to?
Belongs to the DOCK family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Note=Mainly located near the cell surface.
Protein: AC4CH_YERE8
Sequence: MNREITFFRRFEADILASRKTITIRDSSESDFRPGEILRVCRNEDGVFFCNILVKSVTPITLDALTERHAEQENMSLDELKKVIKDIYPGLEQFYVIEFTRC
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: NU4LM_GULGU
Sequence: MSMVYINIFLAFTLSFMGLLIYRSHLMSSLLCLEGMMLSLFVMMTVTILTNHLTLASMTPIILLVFAACEAALGLSLLVMISNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MINE_DEIDV
Sequence: MFSWMKRGRSKETLKDRLELVLAYDRAQIPPGKVDALRNDLLEVVRRYFPTGNSSVEIEQRGDMVVLMANIPIDDTPPVRKSS
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: GALR1_MOUSE
Sequence: MELAMVNLSEGNGSDPEPPAPESRPLFGIGVENFITLVVFGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYHQRLFHRDSNQTFCWEQWPNKLHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHVVHLWAEFGAFPLTPASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHVCDESPRSETKENKSRMDTPPSTNCTHV
What is the function of this protein?
Receptor for the hormone galanin.  The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
What are the official names of this protein?
Galanin receptor type 1, GAL1-R, GALR-1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL3_ENCCU
Sequence: MSCRKFNAPRHGSLQFCPRKRSKTIRPAAGAFPADDRSQPVHLTGFMAYKAGMTHVVRTKTQVAKNKQLSREIMDAVTVLEAPPMVVYGIVGYEKTVTGLRRLPIVTAAYVSDGVLRRMFGNRYASKESAGQFCKGSVCESRVEMIKERAHCVRVLVQTQPTLIKGLGLKKAHIAEIQVNGGSISEKVEWALGRLEKEIAIGEVFGVNENIDTIGVTKGKGFQGTVKRFGVRKQPRKSRKGIRKVACIGAWHPSRVMYSIARAGQMGFHRRTEKNKRVYMIGNGSSNIKTEFDLTEKPISPMGGFPHYGEVRNDFIMVKGAVVGARKRVVTLRKSLLRQRAGEELVIKFVDTSSKIGHGRFQTSAEKKAFYGARKADIAAEIH
What are the official names of this protein?
60S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELN_HUMAN
Sequence: MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGAAGAGVLGGLVPGAPGAVPGVPGTGGVPGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAGADEGVRRSLSPELREGDPSSSQHLPSTPSSPRVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRKRK
What is the function of this protein?
Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely.  Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).
What are the official names of this protein?
Elastin, Tropoelastin.
What is the protein family that this protein belongs to?
Belongs to the elastin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Extracellular matrix of elastic fibers.
Protein: ACCD_RHILS
Sequence: MNWITNYVRPRINSMLGRREVPENLWIKCPETGEMVFHKDLEGNKWVIPASGYHMKMPAKARLADLFDNGEFESLPQPKVAQDPLKFRDSKKYSDRLRDSRLKTEQEDTILAGVGKVQGLKLVAVVHEFNFIGGSLGMAAGEAIVKAFERATAEKCPLVMFPASGGARMQEGILSLMQLPRTTVAVDMLKESGQPYIVVLTNPTTGGVTASYAMLGDIHLAEPGAEIGFAGKRVIEQTLREKLPEGFQTSEYLLEHGMVDMVVKRHDIPETLARLLKILTKKPVSAANDMNSGAIALAASA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_ACICA
Sequence: MIDYTQYPDARGHFGIHGGRFVSETLMAALEDLENLYNRMKNDEQFLAEFDRDLAYYVGRPSPLYYAERWSKKLGGAQIYLKREDLNHTGSHKVNNTIGQALLAKLSGKKRIIAETGAGQHGVATATIAARLGLECVVFMGAEDVKRQAMNVYRMRLLGATVIPVQSGSKTLKDAMNEAMRDWVTNVDSTYYVIGTVAGPHPYPQLVRDFQSIIGREARRQIQEQAGRLPDALVACVGGGSNAIGLFYPFLNDQDVKMYGVEAAGHGIETGKHSAPLNAGHVGVLHGNRTYLMSDPQGQIIETHSISAGLDYPGVGPEHSFLKDMHRVEYVPIDDNEALQGFRDLTRIEGIIPAIESAHAMAYVTKLAPTMDKDQIIIANVSGRGDKDLMTVARIDGIEMVEM
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: CYB_MURHA
Sequence: MINLRKTHPLMKIINQSFIDLPTPSNISAWWNFGSLLGACLIIQILMGLFLAMHYTSDTLTAFSSVAHICRDVNHGWLIHNLHVNGASMFFMCLFLHMGRGIYYGSYLYKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLAEWIWGGFAVDKATLTRFFAFHFILPFIVVALAIVHLLFLHETGSNNPSGINPDSDKIPFHPYYTIKDALGMTLLLLALLLLALFSPDSLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILILLIIPLLHTANQRSMMFRPISQTLFWILTANLITLTWIGGQPVEQPFIIIGQLASMLYFLLILVLMPLAGLLENYMLKPEW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
Protein: FXYD3_RAT
Sequence: MQEFALSLLVLLAGLPTLDANDPEDKDSPFYYDWHSLRVGGLICAGILCALGIIVLMSGKCKCKFSQKPSHRPGDGPPLITPGSAHNC
What is the function of this protein?
Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell.  Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1.  Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes.
What are the official names of this protein?
FXYD domain-containing ion transport regulator 3, Sodium/potassium-transporting ATPase subunit FXYD3.
What is the protein family that this protein belongs to?
Belongs to the FXYD family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RNH2_RICBR
Sequence: MEIDILHFEKKYPNFILAGIDEAGRGPLAGPVVAAAVIVDQNNIIAGIKDSKKLSKKKRELLYEQITANYIWATGIISHTEIDKINILEATKKACILAAENLSTKPEIVLVDGNMQFSDKRFISIINGDNLSLSIAAASIIAKVTRDRLMLELSNEFPQYLWHKNSGYGTKEHAQAIKEYGLSPYHRLSFTKALYK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_BUCAT
Sequence: MLKIFNTLTSTKEIFTPIKKNRVNLYVCGVTVYDFCHIGHGRTFVVFDMIVRYLRFSGFQVKYVRNITDIDDKIISKSTKEKKKINTFTASMIKEMHKDFDLLGISVPDEEPRVTDYIDNIIRIITTLIKKKHAYIHKNGDVIFSIDSDPNYGTLSRQSLTSLESGSRIPLNNMKKNPLDFILWKSSNKEEYSWDSPWGKGRPGWHIECSAITNVFFNNSIDIHGGGSDLLFPHHENERSQSICFNNKSMINFWMHTGMVILNNKKMSKSLGNVYFLRNILKDCDAEVLRYFFLSTHYRHPIYYCEKNLDQAYTSLKYLYTALYDTNPFFNNEEGLNFELEFYNAMNDDFNTPAVFSIFFKIARKINFLKNKDILKTNKFAFRLKYLANNLGFLFQDPKEFLQKKTTLNLLTLKEIQLLIEKRNIARQSKLWQEADNIRKKLMSLDIILEDLPDKTIWRKNKKS
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUFS_ECOLC
Sequence: MTFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPGQVIDTEAEFYRHGYAAVHRGIHTLSAQATEKMENVRKQASLFINARSAEELVFVRGTTEGINLVANSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTLFDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHLVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLESVPDLTLYGPQNRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVDRLVTGLQRIHRLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPR1_SCHPO
Sequence: MNNPFKDMDCYEILQVNHDSDLQEIKANYRKLALQYHPDRNPGIEDYNEIFSQINAAYNILSNDDKRKWHEKDYLRNQYSVQIEDVLQHLQTIEKIPFESTSAFVERLRQDEKIAGSTDDLPTLGDTTWLWTYAKPIYQKWLRFSTKKSFEWEALYNEEEESDAATRRLMKRQNQRQIQYCIQRYNELVRDLIGKACDLDPRRKNVVKLSDGERYNSLQEASRKQSERDRRQYQETFKNQSIASWTIIDQEETSSDDESLSKEIVNSNPIMCMVCNKNFRSQNQLENHENSKKHKKNLRKMNQEIKKHAKEAQKNAESNKQPEDAPSESPYSNKVSSSDFYTRSFEEIEKTFTFVEISDNEFYTASEDGFLNEDDKLDQD
What is the function of this protein?
Reticulophagy receptor required for autophagosomal sequestration of endoplasmic reticulum (ER) membranes during ER stress (Ref. 5).  Confers resistance to ER stress by promoting the autophagic degradation of the ER (ER-phagy or reticulophagy) (Ref. 5).  Acts as a bridging molecule to mediate the association between atg8 on the autophagic membrane and the vesicle-associated membrane protein-associated proteins (VAPs) scs2 and scs22 on the ER (Ref. 5).  May play a role in meiosis (PubMed:16303567).
What are the official names of this protein?
ER-phagy receptor 1, Meiotically up-regulated gene 185 protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Preautophagosomal structure. Note=Accumulates at the preautophagosomal structure when autophagy occurs.
Protein: NU4C_VITVI
Sequence: MNYFPWLTLIVVLPISAGSLIFFLPHRGNKVIRWYTIFICMLELLLTTYVFCYHFQLDDPLIQLVEDYKWINFFDFDWRLGIDGLSIGPILLTGFITTLATLAAWPVTRDSRLFHFLMLAMYSGQIGSFSSRDLLLFFIMWELELIPVYLLLSMWGGKKRLYSATKFILYTAGGSIFLLLGVLGIGLYGSNEPTLNFETSANQSYPVALEIIFYIGFFIAFAVKSPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLVRINMELLPHAHSIFSPWLVVVGTMQIIYAASTSSGQRNLKKRIAYSSVSHMGFIIIGIGSITDTGLNGAILQIISHGFLGAALFFLAGTSYDRIRLIYLDEMGGIAIPMPKIFTMFSILSMASLALPGMSGFVAELIVFFGIITSQKFLLMPKILITFVMAIGMILTPIYSLSMSRQMFYGYKLFNAPNSYFFDSGPRELFVLISIFLPVIGIGIYPDFVLSLSVDKVEAILSNFFYR
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: IBP4_RAT
Sequence: MLPFGLVAALLLAAGPRPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCALGLGMPCGVYTPRCGSGMRCYPPRGVEKPLRTLMHGQGVCTELSEIEAIQESLQTSDKDESEHPNNSFNPCSAHDHRCLQKHMAKVRDRSKMKVVGTPREEPRPVPQGSCQSELHRALERLAASQSRTHEDLFIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADSLQE
What is the function of this protein?
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.  They alter the interaction of IGFs with their cell surface receptors.
What are the official names of this protein?
Insulin-like growth factor-binding protein 4, IBP-4, IGF-binding protein 4, IGFBP-4.
What are the subcellular locations of this protein?
Secreted.
Protein: COAE_CHLL3
Sequence: MTPSHPFLVGVTGGIGSGKSTLCRFLEKMGCELFEADKVARQLQVSDPEIMEGIKSLFGKDVYSKTRSGKLSLDRKRIAREVFSHPATLGALNNLIHPKVYNAFRQRALEAFGRGTAILVMEAAILFETGRAADLDFVVVVAADTETRIKRAVTRGLGTPEDIRKRIALQWPQEMLVARADYVVNNDIGKTKLKEEAGRLYSVLVEAAASGPDCQSKRR
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMD_CHRVO
Sequence: MTHPQTIALVESLDHEGRGVAHVDGKTLFIDGALPYEKVIYSSYRKKPSYENAQTSAVLKESFMRADPRCPHFGVCGGCSMQHVEFTAQVAIKQRVLEDNLKRIGKVKAERVLTPIAGPAWHYRHRARLSARMVAKKGGVLVGFHEKSSSYIAEMRECHILPKHISDLIMPLREMIATLSISQRMPQVEVAVGDKLDILVFRNMDDITDADFAILKAFSDKHGAAERPLQIWLQPKGPDTCYPIYPLDAPKLTYSMPEFAVEMPYYPTEFTQVNPQINAVMVARALKFLDPQPGERIADMFCGIGNFTLPIARSGAVVHGMEGSQPLVRRAVENATHNGLQDKVSYEMANLFDVTEESFAALGKFDKMLVDPPRDGAVQLLKAITEETAPQRIVYVSCNPSTLARDAGVLVHTKGYTLKAAGIINMFPHTAHVESVAWFEKTGPCKTRKEVEEIEALEAAEREAAKAARLAEENAEKARKAAELAEKAAAKEARRAHYFAEKARRDAEEAASDQ
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: RSMA_SINMW
Sequence: MAALDGLPPLRDVIQRHGLDAKKALGQNFLLDLNLTQKIARTAGPLEGVTVIEVGPGPGGLTRAILALGAKKVVAIERDSRCLPALAEIGAHYPERLDVVEGDALKVDFEALADGPVRIIANLPYNVGTQLLVNWLLPGRWPPFWQSMTLMFQREVGLRIVASPDDDHYGRLGVLCGWRTKASLAFDVPPQAFTPPPKVTSTVVHLEPIEVPIPCSPAVLEKVTQAAFGQRRKMLRQSLKPLGGEALLAKAGIDPKRRAETLSVEEFCRLANCL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U23_HHV6U
Sequence: MLFLSFLLVCLCEEVRMLNLMTTEVSATEFASIASKNMETDVSTSSDYLTGKSETTFSANSETWGKNVTEISIDSETYLNQSFMVTSTLAVETTDRSIGNNVNVTSSFPTVKGDETQNIETSFTVISASTFSDVSEKTPQGLSTKSTPKKTVQALWETDTVQVLEFTDTHEGDEEYFKDFLSSLVIWIGGISFIGAFVILIVILCNWYKKDKQRSLFWDEEKKPDVQMRRDVKTCR
What are the official names of this protein?
Glycoprotein U23.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ATPF_CHLAA
Sequence: MEALGINPTLFIAQLINFLLLIFILRALLYRPVMNLLNERTRRIEESVRDAEKVREQLANARRDYEAEIARARQEAAKIVAQAQERAKQQEAEIIAQARREAERLKEEARAQAEQERIRMLSEAKSQIADLVTLTASRVLGAELQARGHDALIAESLAALDRRN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ESA1_NEUCR
Sequence: MSPPGGDATVGSDEKRQKGKATPDTIKMGCIAMVMKEGQLRRAEILSIKDTKSGRQFYCNFDNFNKRLDEWVPAARIDFEQDVEWPNPDKDKQKDAKTKKNNSTVSKKQPSKKNNQKKASKREQSVASDGQTPHPWTEFVESQPGKNNRQRGKTEDGTDVNASLEVGGDKGVKRKADEIDMDEDEIPAAKKQRQPSFSREQEIEKLRTSGSMTQNPTEISRIRNISKVEFGRYVLFPWYFSPYPQIFDQEDCIYICEFCLSYYGELKSFVRHRQKCTLHHPPGNEIYRDDYVSFFEIDGRRQRTWCRNLCLLSKMFLDHKTLYYDVDPFLFYVMTTRDDRGCHIIGYFSKEKESTDGYNVACILTLPQYQRKGYGRLLIQFSYELSKIEGKLGSPEKPLSDLGLLSYRQYWSENIIDILLGYNERKEACTIENIAVALAMTTQDVEHTLQALKMQVYHKGEHKIVVPEKLIKQREKSKAKQKRLIDPERIQWKPPVFTALNRTWGW
What is the function of this protein?
Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A. Z (By similarity).  Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac (By similarity).  The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation.  The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination (By similarity).  Recruitment to promoters depends on H3K4me.  Also acetylates non-histone proteins (By similarity).  In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively (By similarity).
What are the official names of this protein?
Histone acetyltransferase esa-1, Histone acetyltransferase hat-4, Protein 2-hydroxyisobutyryltransferase esa-1, Protein acetyltransferase esa-1, Protein crotonyltransferase esa-1.
What is the protein family that this protein belongs to?
Belongs to the MYST (SAS/MOZ) family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Following DNA damage, localizes to sites of DNA damage, such as double stand breaks (DSBs).