PharMolix/UniProtQA huggingface dataset:
Protein: HXK_KLULA
Sequence: MVRLGPKKPPARKGSMADVPANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKGGNIPMIPGWVVEYPTGKETGDFLALDLGGTNLRVVLVKLGGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLNIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCEYGSFDNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAHIAADGSVFNRYPGYKEKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQKRLAAGKSVGIKGE
What is the function of this protein?
Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) (PubMed:12882981).  Has higher affinity for D-glucose (PubMed:12882981).  Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (PubMed:12882981).
What are the official names of this protein?
Hexokinase.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
Protein: DAPE_ROSDO
Sequence: MPAVDPVRLTADLVRCASVTPADEGALDILHDVLSDAGFDCAWADRGGIRNLFARWGRKGHPKTFGFNGHTDVVPIGNADDWSMPPFGAEVKDGIMYGRGTTDMKSGVAAFAAAAVDFVRDTPPDGAIVLAITGDEEGDATDGTTALLAYMAAQGEQMSACLVGEPTCPDRMGEMIKIGRRGSMTAWITFIGKQGHAAYPHRACNPLPALMRLMDRLASHKLDEGTEFFDPSTLAIVTVDTGNPATNVIPASCSGTVNIRFNDAHSGASLTEWIKTELSRIEGEFGVQIDLRIKISGESFLTPPGPLSALVSKAVKAQTGIEPVLSTTGGTSDARFVKDHCPVVEFGLVGQSMHQVDEHVKTDHIVELKAIYSRILTDYFA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: T2R50_PAPHA
Sequence: MIPFLHIFFSVLILVLFVLGNFANGFIALVNFIDWVKRKKISLADQILTALAVSRVGLLWALLLNWYLTELNPAFYSVELRITSYNAWVVTNHFSMWLAASLSIFYLLKIANFSNLSFLNLKRRVRSIILVILLGSLLFLVCHLLAVNMDENMWTEEYEGNMTGKMKLRNAAHLSYMTVTTLWSFIPFMLSLISFLMLIFSLCKHLKKMQLHGEGSRDPSTTVHIKALQTLISFLLLCAIFFLFLIISVWSPRRLQNEPVFMVCKAVGNIYLSFDSFVLIWRTKKLKHIFLLILCQIRC
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 50, T2R50.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VF184_IIV6
Sequence: MTDVFKVLTPAKNINGEHTHVSMGDTKGTWYLSLNKSQEFYNVYGLALKNGQKLSLAEKPGEYVPLLVDIDLKKEVNGYPNYGSNDFYNDEDIINVVKIFQNAVSENVNRHAKKLTNKNLRCVVLEKDIFIERINESEDKYIVKKGIHLHFPHLFLPKKDIKNSFMPVVKTMIDQENVFQDFINSMDNQIMPSSLIDDISSKYWLMYGSSKEGLNKPYKISKILDHNQQEISISKCFKSETCIDGSPITDTNVEFELPMLLSINPKPSIISNKLFYFKEAPVKLCDALLPVVNNNREKEGRMSSREIEKMKKLTSFLSVSRADDYNQWWTVGITLFNIGTGRDCEEEALEAWKMFSSQSTKYDESRCDLEWAEMKKKNRPLNARTMGSLIFMAKSDNPVALEKYLLAEQMNIENWTSHQNLDVESIKKLKVPVFDTEIAEMFVSQHEDEYLNGNLGWFKFNGTIWSSLESVGRHMRPSLVSLSRSYLNLIPALKYITKTLQNDDEGYEPSDSGFGFDDDDSASTSGGKTTAEITKLVNSKIKLINDLAKKCQNNGPQMSLMKVIEDMIGIDNLNDKMDQNKQLIAFTNGVYDLSLFTFRQGLPEDYITRQMTIPYDITLTMENPKVIKMLNFFKKIFPDEELFEYFMLENCEMYIGGNRDKILQIWTGEGDNGKSVTNKIIENKFGKLSVKFPKGMVTGDPPKAGACFPELTRAQRGVRWAVVDEFAPDETVNAGVIKNLTGGIDNLYARDIQQKGKDVIDIDPFFKLIFICNTIPNIRNPDNATWNRIRVIPFESTFKDSIDDISLEEQKRDKIFLKDTSFCEKETIRELGEAFAWYLIQVFIKKEQARRDARLNGKSFKIKIPAKVNEATELYKAQGNAIADYFNDKFEISDDDNDTINIKLYYQDFLLWFSQTHSNKNVNIDKKKFMKLFVQHAKGDMNTFICTKLKLKETLEEFNLENNEENGMPLF
What are the official names of this protein?
Putative helicase 184R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 184R family.
Protein: SSTT_STRA1
Sequence: MKRFLKAWRKTSLIKKITIGVVIGLFLGILVPKASAIGLLGQLFVGGLKAIAPLLVFTLVISALSQHREGGKTNMSTIIGLYITATFAAALIAVVVNYIFPLTLILKTPAKTDLLPPKGISEVFQSLLLKIVDNPIHAITEANYMSILFWAVIFGLAMRSSNQRTKDLMQTFADATSQVVKWIINLAPIGIMGLVFTSISENGIGILGDYGLLILVLVGTMLFVALVVNPIIAFVMMRKNPYPLVLRCLKDSGITAFFTRSSAANIPVNMRLCEDLGLDKDTYSVSIPLGAAINMAGAAITINILTLAAVNTLGITVDFPTAFLLSVVAAVSACGASGVTGGSLLLIPVACSLFGISNDVAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAVAEKSVFGKK
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GPMA_BACAA
Sequence: MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKRAIRTLWIVLHEMDLAWVPVHKCWKLNERHYGALQGLNKDETAKKYGEEQVHIWRRSIDVRPPALTEDDPRYEMNDLRYKALKKGEFPLTECLVDTEKRVLDYWHSEIAPKLKNGNKVIISSHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDENLRPIRHYYLSMDGEVPEGEIPKHITF
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: TWF2_CHICK
Sequence: MTHQTGIHATTELRDFFAKARNGSVRLIKVIIEEEQLVLGAHKELARRWDVDYDAFVLPLLDEQQPCYVLYRLDSQNAQGYEWLFISWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDEMFGTVKEDVSLSGYQKHVSSCSAPAPLTAAEQELQQIRINEVKTEISVESKHQTLQGLAFPLQLDAQQAIQTLKQKKINYIQLKLDLERETIDLVHTSPTDISDLPKRIPQDSARYHFFLYKHSHEGDYLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDTVEQEFCLEIAKKIEIDDGAELTAEFLYDEVHPKQHAFKQAFAKPKGPVGKRGQKRLIKGPGENGEDS
What is the function of this protein?
Actin-binding protein involved in motile and morphological processes.  Inhibits actin polymerization, likely by sequestering G-actin (By similarity).
What are the official names of this protein?
Twinfilin-2.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Note=Perinuclear and G-actin-rich cortical actin structure sublocalization.
Protein: RNC_VIBCM
Sequence: MTPPMNKLTSKLGYTFKETELLNLALTHRSANGKHNERLEFLGDSILSFVIADELYRRFPKVNEGDMSRMRATLVRGNTLAELGREFDLGDYLKLGPGELKSGGFRRDSILADAVEAIIGAIYLDSDLETARSIVLEWYHGRLEEIKPGASQKDPKTRLQEFLQGRRKPLPVYTVTNIKGEAHNQEFTVACEVAGMDTPVIGKGTSRRKAEQAAAETALEQLTNG
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOAP2_TITOB
Sequence: MQFKKQLLVIFFAYFLVVNESEAFFGTLFKLGSKLIPGVMKLFSKKKERSLMKRELKNLYDPYQRSVEMERLLKELPLY
What is the function of this protein?
Antimicrobial peptide (PubMed:27917162, PubMed:29848960).  Shows antibacterial activity against all M. massiliense bacterial strains tested (PubMed:29848960).  Has antifungal activity against Candida spp.  and two Cryptococcus neoformans strains with MICs values ranging from 6. 25 to 200 uM (PubMed:27917162).  Also shows an inhibitory activity on C. albicans biofilms at high concentrations (PubMed:27917162).  Exhibits chemotactic activity for monocytes, neutrophils, and eosinophils (PubMed:29848960).  Shows low cytotoxic activity and has weak hemolytic activity on human erythrocytes (PubMed:27917162, PubMed:29848960).  In vivo, treatment of infected mice with M. massiliense reduces the bacterial load in the liver, lung, and spleen (PubMed:29848960).
What are the official names of this protein?
Antimicrobial peptide ToAP2.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Medium-length antimicrobial peptide (group 3) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Has an amphipathic alpha-helical conformation.
Protein: LOLA_HELPJ
Sequence: MKAFLKICMVLIFVGVAHAKNPLTLSKEEEVLQNLQSFSAHFKQVLKNEKPLVYYGVLKAKAPNWALWVYEKPLKKEIYMNDKEVVVYEPNLFQATITPLKDKTDFFTILKQLKKQTDGSFKTTINKTTYRLVFKDGKPFSLEFKDDMNNLVTITFSQAEINPKIPNEIFVFNPKDENIDIVRQ
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SBDS_BOVIN
Sequence: MSIFTPTNQIRLTNVAVVRMKRAGKRFEIACYKNKVVGWRSGVEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKPNKSTKQQALEVIKQLKEKMKIERAHMRLRFILPVNEGKKLKEKLKPLIKVIESEDYGQQLEIVCLIDPGCFREVDELIKKETKGKGSLEVLSLKDVEEGDEKFE
What is the function of this protein?
Required for the assembly of mature ribosomes and ribosome biogenesis.  Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export.  Required for normal levels of protein synthesis.  May play a role in cellular stress resistance.  May play a role in cellular response to DNA damage.  May play a role in cell proliferation (By similarity).
What are the official names of this protein?
Ribosome maturation protein SBDS, Shwachman-Bodian-Diamond syndrome protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SDO1/SBDS family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Note=Primarily detected in the cytoplasm, and at low levels in nucleus. Detected in the nucleolus during G1 and G2 phase of the cell cycle, and diffusely distributed in the nucleus during S phase. Detected at the mitotic spindle. Colocalizes with the microtubule organizing center during interphase (By similarity).
Protein: PSBH_CROS5
Sequence: MAQRTRLGDLLRPLNSEYGKVVPGWGTTPLMGVFMGLFLVFLLIILQIYNSSLILNGFTVTWGG
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: ALGA_PSEAE
Sequence: MIPVILSGGSGSRLWPLSRKQYPKQFLALTGDDTLFQQTIKRLAFDGMQAPLLVCNKEHRFIVQEQLEAQNLASQAILLEPFGRNTAPAVAIAAMKLVAEGRDELLLILPADHVIEDQRAFQQALALATNAAEKGEMVLFGIPASRPETGYGYIRASADAQLPEGVSRVQSFVEKPDEARAREFVAAGGYYWNSGMFLFRASRYLEELKKHDADIYDTCLLALERSQHDGDLVNIDAATFECCPDNSIDYAVMEKTSRACVVPLSAGWNDVGSWSSIWDVHAKDANGNVTKGDVLVHDSHNCLVHGNGKLVSVIGLEDIVVVETKDAMMIAHKDRVQDVKHVVKDLDAQGRSETQNHCEVYRPWGSYDSVDMGGRFQVKHITVKPGARLSLQMHHHRAEHWIVVSGTAQVTCDDKTFLLTENQSTYIPIASVHRLANPGKIPLEIIEVQSGSYLGEDDIERLEDVYGRTAEPALQVVAGSR
What is the function of this protein?
Produces a precursor for alginate polymerization.  The alginate layer provides a protective barrier against host immune defenses and antibiotics.
What are the official names of this protein?
Alginate biosynthesis protein AlgA.
What is the protein family that this protein belongs to?
Belongs to the mannose-6-phosphate isomerase type 2 family.
Protein: MIAB_SYNP6
Sequence: MSTPRRYHITTFGCQMNKADSERMAGILEDLGYIWSEEANDADLVLYNTCTIRDNAEQKVYSYLGRQAERKRQQPDLTLIVAGCVAQQEGESLLRRVPELDLVMGPQHANRLADLLAQVEAGSQVVATEEVEIAEDITQPRRDSTITAWVNVIYGCNERCTYCVVPNVRGREQSREPAAIRAEIEQLAAQGYREITLLGQNIDAYGRDLPGSTPEGRHLHTLTDLLYTIHDVPGIERIRFATSHPRYFTERLIRACAELPKVCEYFHIPFQSGDNDVLKAMARGYTVERYLRIVEQIRDIIPDAAISADAIVAFPGETEEQFENTLKLVEQVGFDLVNTAAYSPRPGTPAANAPNQLSEEVKQDRLQRLNHLVAQMAADRSQRYLGRTEEVLIEATNPRNPQQVMGRTRTNRLVFCDGTIAQLEGQLVPVRITETRAFSLTGQILSPVAAGC
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THF1_SOLTU
Sequence: MAAVTSVSFSAITQSAERKSSVSSSRSIDTFRFRSNFSFDSVNVRSSNSTSRFVVHCTSSSAADLPTVADTKLKFLTAYKRPIPTVYNTVLQELIVQQHLTRYKKSYQYDPVFALGFVTVYDQLMEGYPSEEDRNAIFKAYIEALKEDPEQYRADAQKLEEWARTQNANTLVDFSSKEGEIENIFKDIAQRAGTKDGFCYSRLFAVGLFRLLELANVTDPTILEKLCAALNVNKKSVDRDLDVYRNLLSKLVQAKELLKEYVEREKKKRGERETQKANETVTKCLGDYQYAGR
What is the function of this protein?
Involved in a dynamic process of vesicle-mediated thylakoid membrane biogenesis.  Required for the normal organization of vesicles into mature thylakoid stacks and ultimately for leaf development (By similarity).
What are the official names of this protein?
Protein THYLAKOID FORMATION1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the THF1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast outer membrane; Single-pass membrane protein. Plastid, chloroplast stroma.
Protein: MFR1L_DANRE
Sequence: METEAEVIPIWQNKPHGSTRSVVRRIGSTLPLKPCPRACFQELPGLPSMRSLDGPLVPTLADIAWIADDEEETYARVRSDTRPLRHEWRPTPLLVMHRNSSVPNFRREGRRVEGLRKPGVTALNRTTALQDELSRLRAQIAKIVAADSDSNPITPDLLSPDDTSMGFSMAPFETAAYQPPPTASFVISDVTEEDEEEEEEEDREEEEEDVSELVPDPMPPVSMTASATFDLDRPTMDFREPEEDTVSLSKSTSFADVMDMLKDMNRLKMSKDRYNRGCTSLREEDSASLISEALRKKFVLKDDDISMRK
What are the official names of this protein?
Mitochondrial fission regulator 1-like.
What is the protein family that this protein belongs to?
Belongs to the MTFR1 family.
Protein: HIGB_ECOL6
Sequence: MHIISKAPFEECARKYPNDALALHSLYRVIKETDFSTPEEMRTAFPNLDNFKYRNKWYVLDVGGNNLRVIAYINFVNKRFFVKHITNHAEYDKLTRYYRENKE
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  A probable translation-dependent mRNA interferase.  Probably counteracted by antitoxin HigA.
What are the official names of this protein?
mRNA interferase HigB, Endoribonuclease HigB, Toxin HigB.
What is the protein family that this protein belongs to?
Belongs to the HigB mRNA interferase family.
Protein: YNE7_CAEEL
Sequence: MKDGFLGIDLSTQQIKAVIIDQNGKVVHTTAINFSTHEKLKKFGTENGVHKNGSVITSPVIMWIEAIDILFNDLRENGWTDKLRGISGCAQQHGTVYWKNGAENSLKGLDESRSLAEQLEMCFSVQKSPIWMDSSTEKQCQELETFVGGDQEMAKLTGSRAHHRFSAAQIKKIVDEKQDVWKDTEKVSLISSFFASLLIGKYALIELTDGSGMNLMNIKTENWHKPLFDFISSDLESKLGTLVHPMTSTGHVHSYWTRRFGIPSDCTVLPFLGDNPSSLAGLSLLPTDIGISLGTSDTVFFFTPTFEPNIDAHVFSHFAPNSGYMAMVCFKNGSLTRERARNLNNSSWDKWDKIMKKTPAGNDNYIGFFFDEDEIVPRKPKGDYTFECSEEELKNKHPEKFARAVFESQCLFKLLYTQKMGFKKSDCSRILVTGGASRNTVLLQILSDVFEMPVCTIDVDGSAALGGAMRSRYVHSKTTKTYSQYYPCDNVSLACQPISANVEVYSNLFKTFKSRFDEFIKQ
What are the official names of this protein?
Uncharacterized sugar kinase R08D7.7.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: SYI_THEFY
Sequence: MSKESTRPFPTLPAQIDLPAMEHEVLRRWEEHKIFERSLEQTQGGPTWVFYEGPPTANGTPGVHHVEARVFKDVFPRFKTMKGFYVERKAGWDCHGLPVEVAVEKELGISGKKDIEAFGIAEFNARCRESVLRNVDAFTEMTRRMGYWVNMDEAYRTMDREYVESVWWAIKQIWDKGLLVQDYRISPYCPRCGTTLSDHELAQGYETVTDPSVYVRFPLTSGPLAGQAALLVWTTTPWTLVSNTAVAVHPEVDYVVATDGSEQLVVAEPLVGAALGDGWTLTGQRFKGAELERWTYQRPFELVEFDSPAHFVVLGDYVTVEDGTGLVHQAPAFGADDMQVCRAYGLPVVNPVRNDGTFEEHLDLVGDEFFKTADAALVADLKDRGLLFKHLDYEHSYPHCWRCHTPLMYYAVPSWYIKTTAIKDQLLAENAKTNWVPANVKDGRYGEWLRNNVDWALSRSRYWGTPLPIWEFPDGRRICVGSLKELSELSGQDLSDLDPHRPYVDDIVIPDPDADPSLPLEQRVARRVPEVIDVWFDSGAMPFAQWGAPHRNQEKFEANFPAQYICEAIDQTRGWFYSLMAVSTLVFGRSSYENVVCLGHILAEDGRKMSKHLGNILEPIPVMDRHGADALRWFMAASGSPWMPRRVGHTVLEEIVRKVLLTYYNSASFFTLYAGAGDGWSHEQLADAPAPQDRPLLDRWILSELHSLIKTVDDALERFDTALAGRALTTFIDDLSNWYVRRSRRRFWAGAGTPEGAAAFATLFECLETLTLLMAPIVPFITDHVWQALRRPDAPESVHLASWPKADESLIDPALSEQMALVRRLVELGRAARVDSGQRVRQPLARALVGAPGFAELPEQLRAQIAEELNVVQLDPLSVVGGDLVDYSVKPNFRALGKRFGKTTPRVAQAIREADAKTLVERLRADNAATVDVDGEQVVLSADEVVVTEQPREGWTVASEAGETVALDLELTPELRRAGVAREVIRLVQDARKSSGLNISDRIHLWWSATDEMTAQAMAEHAEAISSEVLAVSFTEGTGDADAYEVVSEEFGITLRLRKA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNLS_MOUSE
Sequence: MSRVLVVGAGLTGSLCAALLRKEITAPLYLGLWDKGGDIGGRMITASSPHNPRCTADLGAQYITCSPHYVKEHQNFYEELLAHGILKPLTSPIEGMKGKEGDCNFVAPQGFSSVIKYYLKKSGAEVSLKHCVTQIHLKDNKWEVSTDTGSAEQFDLVILTMPAPQILELQGDIVNLISERQREQLKSVSYSSRYALGLFYEVGMKIGVPWSCRYLSSHPCICFISIDNKKRNIESSECGPSVVIQTTVPFGVQHLEASEADVQKLMIQQLETILPGLPQPVATICHKWTYSQVTSSVSDRPGQMTLHLKPFLVCGGDGFTHSNFNGCISSALSVMKVLKRYI
What is the function of this protein?
Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)(+).  The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure.  Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk.  High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
What are the official names of this protein?
Renalase, Monoamine oxidase-C, MAO-C, mMAO-C.
What is the protein family that this protein belongs to?
Belongs to the renalase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS21_ACIBS
Sequence: MPQVKLKEGEPVDVAIRRFKRSCEKAGVLADVRKREFYEKPTQERKRKKAAAVKRYQKKLARESVRTTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RAV2_YEAST
Sequence: MSVDLFPNDRFGAEDKYDNFKDAVKECSWLIEEIVKPQLPNIIDNFSKCLEMLESDQIFKMPVSNGIPNESNKQNDSPTVKGVITRQGQYIVDFHIVVRFPQFQRGKQVMFRMNTGLNFLLIQFSKIMTHLKNILEILNQLQVATDVSEFVSKFGVAMELLNHSLILLQNPPRDLVFPEDNNFAMKEMFQDCYSVCESTAHILGLELTLCRNELCIELRNLIKVTKKPWCEIDSKTGRSFCDQIRNQVTNERNKTLSKILSENGVQVQDSTLLNHIISSFQSEAITLPEAQELLRRGVTFDNRVVMECEKLIVSTSDPTLISISAKLNSLKASMANHQANLVASKQLSTYK
What is the function of this protein?
Component of the RAVE complex, which is required for stable assembly of the vacuolar ATPase complex V-ATPase under many conditions.  May be required for transport between the early endosome and the late endosome/prevacuolar compartment (PVC).
What are the official names of this protein?
Regulator of V-ATPase in vacuolar membrane protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=May be membrane-associated and localize to early endosomes via its interaction with RAV1.
Protein: PPIL4_SCHPO
Sequence: MSVLIETTVGDLVIDLFVKEAPKTCENFLKLCKLKYYNFCPFYNIQHNYTCQTGDPLGPTGDGGRCVWNVLNKGTRFFKAEFNPSLVHNKMGLVSMSTATISSRDDKLLVCGSQFIITLSDNLEGLDERYPIYGQVAEGFDTLLKINDAICDEEGQPYRDIRIKHTIILDDPFEDPPDLVEPLRSPSPTPEQLATVRIGENEQIESETSEDKLQREKEMEAEAEAVTLEMIGDLPFAHVAPPENVLFVCKLNPVTQDEDLELIFSRFGKIISCQVIRDKETGDSLQYAFIEFDNKESVEKAYFKMQNVLIDDSRIHVDFSQSVARYRQYYNSNRDRKRSSSRSDDREYHRRSDGRYDRSNYRDDYRHRRKERDHRDDQSSFRNERFSNYYGDDRSYHKRRNTGNKNCDDHLRDKSPERRYRYDRRYRDDRYR
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase cyp6, PPIase cyp6, Rotamase cyp6.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RT106_CHAGB
Sequence: MATQLDVQTLRSVFQSRPDILSNIERNADTPARTTLFNEIASFVYERLGSADPEDGPASKRRRIDIAQLPTHPQPNGHAHGRAPPAGLSVDVAATDPVLLELRDISVTAPQRKKYDLCFTKNFLYARASGTSVPVQGVVYPLKDIEHAFYLPVPDKSQAQYNYVLLPRDSYLPTAKQAGANSGGGLQPLEPLVFTVPAAAPKPGSVVGPSSAAAEAVSDTYSSLLHWALTTSMRSAGNHSCQLVASDPKLFHSVARQPHRPNEKAVHVKAFRGSKDGFLFFLPTGILWGFKKPILFLPLDRIVAVSYTNVLRTTFNIVVELDTDIPGEANIAIEKEIEFGMIDQEDYGGIDETYVRRHGLADRSMAEQRKAKRELVENIKKPAAGDELAGGEGDADGLTALERAQREAEQQLQDEEDEMEEDYDPGSEGDSEGEGGSSGEDDDDDEAQGDYDDEEDDEAEGLEN
What is the function of this protein?
Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing.  Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA.  Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity).
What are the official names of this protein?
Histone chaperone RTT106.
What is the protein family that this protein belongs to?
Belongs to the RTT106 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PTER_DROGR
Sequence: MARIQTVLGSITPNLLGRTLTHEHVAMDFEHFYKPPPADFQSELEQKISMATLGYVRLYPYSSKENVRFYDEEALEASRKDVLLYKKHGGGAIVENSSYGLKRNLEFIVDLAKTTGVHFIAGTGHYIHATQDASHKNLTVEQMTDLYSKDILTGIEVNGRMVKSGFIGEVASVYPVQEFERHSLLAAGEIQEVLGCGVSLHPHRVSKAPFEILRLYLEAGGRANKCVMSHLDRTLFDMDELLEFAKMGCYLQYDLFGTECSYYQLNSAVDMISDGQRIDNIIKLINEGLVDRLLMSHDIHTKHRLTSYGGHGYHHIHMNILPRMFQRGVTLDQVEQMTVTNPANWLSFSA
What are the official names of this protein?
Phosphotriesterase-related protein, Parathion hydrolase-related protein.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.