PharMolix/UniProtQA huggingface dataset:
Protein: MED5_ASPCL
Sequence: MTAPGQWGTFLHQCLMHRIDATEFKSLLKLMFQKCPITETALLDALLQTRLKSRIKWDPLLPLYIDCLCRMGRVRTSTVLTSLLKYSSIHEDSQPLVPAAKEGSKGYTLMTDIRVIQDAMLSVSTGGTPKTIAEAIAIFFSIIDWIHAVVAWHHSHLDHSQHPGGLMSSPDVVSVFESLGILLAALSGTGKGLEVLSADSHEELKVKLGQALSAYLPLCVEVSLPLRNRLDGLQKEFHLYGEPSSKSLNVPMMDNVNVNALQFEASVMDGPVIHSRAGLYVYINAMLVGRPLVDDSMLINFLANRYGGHYEVLIEEIITAAFDVLSNAMYRNESSRTMFLFRSFLVNKLPPFFAAMLASTMVSIPMEMCISQALGRLDPNTFPSFSQMFEMQGNTVLSDVRQEFLFACASHKLIPESSIERMLGENPMQALPVGYNKDELVSQINTNPERAEQLINEIESMEGNAGAIVGAITEIMHNLCNQKETVTLKNICNSLSRRPQALDVILLFRSAKQVLQPLCGLLDSWHWDEDQGENQPVYDEFGSILLLVLAFKYRFDLRPADLGISSNDSFVLKLLERGSCSQKLDALDEKQNKNLGTWIAALFIAEGISEETMSACSPQEFYLLVATLFSQSLGACETGKLEFDTLKGGFEYLLEPFLLPSLVFALTWLGNHIWETEPEPSIALKALHSLVNPSSISGEGREIHRTVLHTVARMLEEQLKDVRTRHPSRTDIKPIMDSLEPCLSFQRVGSCHRSELEGWTTHAGGGLLGSIRSTFQALVLWSANPEVSMAPPSYTHRQVVAGIRMLGAARVFGALVDELVKLQTQTQTQTQAGSSDLALDLAATLVCAPLSEAFAVEQNSHHPVDPSKEALPRCAVLTLRDALALQHENVPKLAEKDPLRAEVVVRLARRVAALLAPPSQVPNLDVNNIIQNMQLGIEGSGPMELDGPGPAADDDDDAENIHRMIDNAAAAAAAAGMDSGVGVGVGQGTGLDTSIDDVLNAADMAVGNPEFLDLDMEGMF
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 5, Mediator complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LUR13_ARATH
Sequence: MKLPFIFLITLLIFVSSCTSILINESSDEERTYSFSPTTSPFDPRSLNQELKIGRIGYCFDCARACMRRGKYIRTCSFERKLCRCSISGIK
What is the function of this protein?
Pollen tube attractants guiding pollen tubes to the ovular micropyle.  Attracts pollen tubes from both A. thaliana and A. lyrata.
What are the official names of this protein?
Protein LURE 1.3, AtLURE1.3, Cysteine-Rich Peptide 810_1.3, CRP810_1.3, Defensin-like protein 214.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted. Note=found at the micropylar end of the female gametophyte, possibly at the filiform apparatus of the synergid cell. Difuses to the surface of the funiculus of the ovule through the micropyle.
Protein: NUOB_BUCCC
Sequence: MKYTLTRVNTKNSISKKYPLRSLKKTSDPIKKQIKNNIFFGTISKYMQYIMNWGRKNSLWPYNFGLSCCYVEMVSAFTSIHDISRFGSEVLRTSPRQADFMVIAGTPFIKMAPVIQRLYDLMLEPKWVISMGSCANSGGMYDIYSVVQGVDKFLPVDIYIPGCPPRPEAYIHAITLLQKAISKERRPLSWIVGEQGVYKYNMLSEKEEKNKKRISIINIDSEDSF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ISPG_ENT38
Sequence: MHNQAPIQRRKSKRIYVGNVPIGDGAPIAVQSMTNTRTTDVAATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGSEERIRAVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIEQPLHLGITEAGGLRSGSVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRARGINFIACPTCSRQEFDVIGTVNALEQRLEDLITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGIRKDRLDNNDMIDQLEARIRAKATILDEAQRISIQQIEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RIMM_YERPN
Sequence: MSKQLNPAVPDQPIVLGKMGSTYGIRGWLRVFSSTENAESIFDYQPWFIQQAGKWQHVELEDWKRHSQDLIIKVKGVDDREAANLLTNCEIIVDSTQLPALEEDDYYWKDLMGCQVVTTTGYELGKIIDMMETGSNDVMVVKANLKDAFGMKERLVPFLHGQVIKKVDLTAQRVEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADI_SHEWM
Sequence: MSDRQQVTNAKGDRIAIVTGLRTPFAKQATAFHGVSALDMGKMVVNELLSRSELDPKEIQQLVYGQVVQMPAAPNIAREIVLGTGMDIATDAYSVTRACATSFQSTVNVAESIMTGNIDIGIAGGSDSSSVLPIGVSKKLAHGLVDLNKARSFGQKLAIFRRLGLKDLLPVPPAVAEYSTGLSMGQTAEQMAKTYNISRADQDALAHRSHSLATETWNSGNLAQEVMTAHVPPYKAFIDRDNNIRENSSIESYAKLRPAFDRKHGTVTAATSTPLTDGASAILLMSESRAKALGYNPIGYIKSYAFSAIDVWEDMLMGPSYATPIALKRAGMELEDLTLIEMHEAFAAQALANMKMFASKKFAQEKLGRNRAIGEIDMNKFNVLGGSLAYGHPFAATGARLITQVCNELKRRGGGTGLTTACAAGGLGAAMIVEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELOV5_XENLA
Sequence: MEVLDKAVNGYIDHLLGPKDPRVKGWLLLDNYVPTIFFTALYLFIVWRGPKYMQNRQPVSCRSILVVYNLGLTLLSFYMFYELVTGVWEGGYNFFCQDTHSGGDADTKIIRVLWWYYFSKLIEFMDTFFFILRKNNHQITVLHVYHHASMLNIWWFVMNWVPCGHSFFGATLNSFIHVLMYSYYGLSAIPAIRPYLWWKKYITQCQLTQFVLTMTQTTCAMIWPCKFPMGWLYFQNSYMISLIILFTNFYLKTYNKKTSSRRKEYQNGSASAVNGYTNSFSSLEDNVKQRKQRQN
What is the function of this protein?
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle.  Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA.  May participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators (By similarity).  In conditions where the essential linoleic and alpha linoleic fatty acids are lacking it is also involved in the synthesis of Mead acid from oleic acid (By similarity).
What are the official names of this protein?
Elongation of very long chain fatty acids protein 5, 3-keto acyl-CoA synthase elovl5, ELOVL fatty acid elongase 5, ELOVL FA elongase 5, Very long chain 3-ketoacyl-CoA synthase 5, Very long chain 3-oxoacyl-CoA synthase 5.
What is the protein family that this protein belongs to?
Belongs to the ELO family. ELOVL5 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=In Purkinje cells, the protein localizes to the soma and proximal portion of the dendritic tree.
Protein: PA2AE_CROVV
Sequence: MRTLWILAVLLLGVEGNLVQFELLIMKVAKRSGLLSYSAYGCYCGWGGHGRPQDATDRCCFVHDCCYGKVTDCNPKTASYTYSEENGEIVCGGDDPCKKQVCECDRVAAICFRDNIPSYDNKYIQFPAKNCQEKPEPC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that significantly inhibits ADP-induced platelet aggregation in platelet-rich plasma of human, rabbit and guinea pig.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 Cvv-E6e, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EFTU2_VIBCH
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAICTVLAKVYGGKARDFASIDNAPEERERGITINTSHVEYDTPNRHYAHVDCPGHADYVKNMITGAAQMDGGILVVAATDGPMPQTREHILLGRQVGIPYIIVFMNKCDMVDDEELLELVEMEVRELLSEYDFPGDDLPVIQGSALGALNGEAQWEAKIVELAEALDTYIPEPERAVDMAFLMPIEDVFSIQGRGTVVTGRIERGILKVGDEVAIVGIKETVKTTCTGVEMFRKLLDEGRAGENVGALLRGTKREEVERGQVLAKPGSITPHTKFESEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDVTGSIELPEGVEMVMPGDNVKMVVDLIAPIAMDEGLRFAIREGGRTVGAGVVAKIIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu-B, EF-Tu-B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLRC_MIZYE
Sequence: ADKAASGVLTKLPQKQIQEMKEAFSMIDVDRDGFVNKDDLKAISEQLGRTPDDKELTAMLKEAPGPLNFTMFLSIFSDKLSGTDTEETLRNAFAMFDELDTKKLNIEYIKDLLENMGDNFTKDEMRMTFKEAPVTGGKFDYVKFTAMIKGSGEEEA
What is the function of this protein?
In molluscan muscle, calcium regulation is associated with myosin rather than with actin.  Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity.
What are the official names of this protein?
Myosin regulatory light chain, striated adductor muscle.
Protein: Y030_NPVOP
Sequence: MAPTRALRLALKKQDYARAADLAIESRANRLFLLDYHDPDFWAYVSRNCYNRDKFLSAFGDKIDWNEVSASPLTTATARTFAAKLNWARVSRQPFLRQQFIYEFGDRLDMQVVSATYNNLSLAVQQKFAAALNWDRVVLSHYMLPEWFEPPICDFINFDAVAKHKHLDKSYINAPHCINKINLGVYMRNINKISDALIVYCLREGRVHELRVVSGAVPWADHMRVFDEYPGLANTLRLDWASVPAWTAACAPPAHYFRRSWPAAFEREFVNSTYWDKFIEYASGTTNAASAAFALFLFDNFKSRVDWRRLQVGDRFVNLAALHRARGPLVALEAAGDDERVWRAYGRFVSGGDAAHCELLIPINMSVRDAYRKMALVQACASQHEHDKARTCERRIALNGGEDALLNWNLLSATQQVCPFNLRHLQNANAQTYRRDNPHYVQDVYEKMIAAQMNINEFL
What are the official names of this protein?
Uncharacterized 52.7 kDa protein.
Protein: GGGPS_PYRIL
Sequence: MKLYEYLVEGTKHFTLIDPDKSVDYLKIAKYALEAGTDGILVGGSLGIRESQITQVVKDIKSIAHVPVVIFPGSISQLTDEADGVLFLSVLNSLDPYYIIGAQIQGAVLLAKHYPKLEVISTAYIIIGDGGAAGFVSMSKPIPYTRPDIVMAYALAANYIGFKAVYLEAGSGAPQPAPPEMVRAARRVFPRILIVGGGIRSGEVAYTIAREKPNVIVTGTLAEEKPEKLGEIIRAIKSA
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_PYRHO
Sequence: MPGKKAPNGEFAGRKLKLKRKKFRWSDIRYKRRVLRLKEKSDPLEGAPQARGIVLEKIAVEAKQPNSGMRKAVRVQLIKNGKVVTAFCPGDGAINFIDEHDEVIIEGIGGPKGGSMGDIPGIRYKVVKVNRVSLKELVKGRKEKPRR
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: FUCM_ECO55
Sequence: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
What is the function of this protein?
Involved in the anomeric conversion of L-fucose.
What are the official names of this protein?
L-fucose mutarotase, Fucose 1-epimerase, Type-2 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_FLAJ1
Sequence: MKKIRNFCIIAHIDHGKSTLADRLLGATQTVTAREEKAQLLDNMDLERERGITIKSHAIQMEYKYKGEEYILNLIDTPGHVDFSYEVSRSIAACEGALLIVDAAQSIQAQTISNLYLALENDLEIIPVLNKVDLPSANPEEVSDDIIDLLGCKLEDIIHASGKTGFGVENILAAIIEKIPPPKGDPEEPLQALIFDSVYNPFRGIEVIFRVVNGEIKKGQKIKFMATDNEYFADEIGTLKLNQVPKNVVSAGDVGYLISGIKEAREVKVGDTITDAKVPTTNMITGFEDVKPMVFAGIYPVDTEDYEDLRSSMEKLQLNDASLVFTPESSAALGFGFRCGFLGMLHMEIIQERLEREFDMTVITTVPNVSYLAYTKKEPEKALIVNNPSDLPEPSKLDRVEEPFIKATIITKADFVGNVMSLCIEKRGLITNQTYLTTERVELNFDMPLAEIVFDFYDRLKTVSKGYASFDYSPIGMRTSKLVKLDVLLNAQTVDALSALIHEDNAYNIGKKMTEKLRELIPRQQFDIPIQAAIGAKIIARETIKALRKDVTAKCYGGDISRKRKLLEKQKKGKKRMRQVGNVEIPQEAFMAVLKLND
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: F221B_HUMAN
Sequence: MEAHEIIEEPHITMDAEKHPPSKDPSAEDLQENHISESFLKPSTSETPLEPHTSESPLVPSPSQIPLEAHSPETHQEPSISETPSETPTYEASLDSPISVVPEKHLTLPPQSRDYVCLSSSDTLKEDLSSESSSNEVPWTRRSTHLSESESLPEHCLSGPSSQVQVDTTEKQEEEAGEVEKGVDASDSTAHTAQPGHQLGNTARPVFPARQTELVEVAKAMHREEFGAQVNNLFQWEKDAALNAIQTGLYIGWRCPHYLWDCFRIGDESRCFCGHLLREHRIISDISVPCKVSQCRCFMFCFIPSRPEEVGEFWLKRRATFDPKAWRAQCRCKHSHEEHAATGPHPCRHHGCCCGCFESNFLCAACDRRWEEHETFFDTQKTRQRGGRPRGTDTVSNWHRPL
What are the official names of this protein?
Protein FAM221B.
What is the protein family that this protein belongs to?
Belongs to the FAM221 family.
Protein: IL18_HORSE
Sequence: MAAGPVEDNCISLVEMKFIDNTLYFVAENDENLESDYFGRLEPKLSIIRNLNDQVLFINQGNQPVFEDMPDSDCTDNAPQTVFIIYMYKDSLTRGLAVTISVKCEKTSTLSCKNKIISFKEMSPPENINDEGNDIIFFQRSVPGHDDKIQFESSLYKGYFLACEKENDLFKLILKEKDENGDKSVMFTVQNQN
What is the function of this protein?
Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses.  Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators.  Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells.  Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
What are the official names of this protein?
Interleukin-18, IL-18, Interferon gamma-inducing factor, IFN-gamma-inducing factor, Interleukin-1 gamma, IL-1 gamma.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=The precursor is cytosolic. In response to inflammasome-activating signals, cleaved and secreted. Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10.
Protein: YFP9_SCHPO
Sequence: MQLLNNWYSLLLTEVAAYFTSTTLFVSILKNAPSLSWLMKYGGHDNFGLKPPLIATKLEVPKRWFWHFYAFISLLNPLFTFFILNTNFPIPIFKNIKEDLMYSKKLQVLLLIYEIHTLRRLYENLRFRKSGSKMLAGHYLLGYLFYTHTFLALLLCGRRSYENTMSSMQFVGLGIYAIGSIWQNASHEHLIAQKNHSQYLVLKKGCFKWITGPHYLGEIIVYTGIALIAQHWLIWLVLGWVLCNMVAISSSYACTVKNKEQSLDFRWTLIPFLY
What are the official names of this protein?
Uncharacterized protein C7D4.09c.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HIDM_GLYEC
Sequence: MASSTSTTTSKEIDRELPPLLRVYKDGTVERFLGSSFVPPSPEDPETGVSTKDIVISENPTISARVYLPKLNNTTEKLPILVYYHGGAFCLESAFSFLHQRYLNIVASKANVLVVSIEYRLAPEHPLPAAYEDGWYALKWVTSHSTNNNKPTNADPWLIKHGDFNRFYIGGDTSGANIAHNAALRVGAEALPGGLRIAGVLSAFPLFWGSKPVLSEPVEGHEKSSPMQVWNFVYPDAPGGIDNPLINPLAPGAPNLATLGCPKMLVFVAGKDDLRDRGIWYYEAVKESGWKGDVELAQYEGEEHCFQIYHPETENSKDLIGRIASFLV
What is the function of this protein?
Dehydratase that mediates the biosynthesis of isoflavonoids.  Can better use 2,7-dihydroxy-4'-methoxyisoflavanone as substrate.  Has also a slight carboxylesterase activity toward p-nitrophenyl butyrate.
What are the official names of this protein?
2-hydroxyisoflavanone dehydratase, Carboxylesterase HIDM.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
Protein: MSH6_CHICK
Sequence: MMSASNLSVIHEVLLVLLNHQRINLPYENLEASLSRMLFLSSFVQEVVQVPIPCNVSANRSVSGVYSPGDLVWAKMEGYPWWPCLIYNHPTEGTIVRGKGSSARIHVQFFDVSPTRGWVSIKYLRPYKGSSDREVLKGGMFYSMKPEIKKAMELADDAMSKDKTKRLELAVCSEPSDTEEAEEEEMEQMSGSASGDSDDSNSEEDVKGNKRVPNRGSAIKAKRRRVLDSDSDRDGSDVEFKPDVKEASSEEASSGVDENEATDVETDEESIEESPIKVPSKRKRGNVSKPSKRSSLENEHSEAPKRAAPVSLEAKSKLTLFAAPENFESQANACSGGTNGFAAWEHEKLEWLQEGKKKDAHRRRQNHPDYDPCTLYVPEDYLNKCTPGMRRWWQLKSQNFDAVICYKVGKFYELYHMDAVTGVNELGLIFMKGSWAHSGFPETAFGRFSAILVQKGYKIARVEQTETPEMMEARCKATAHTTKFDKVVRREICRIITKGTQTYSIIDCDPTENHNKYLLCVKEKEDSSGQRVYGVCFVDTSVGKFYVGQFSDDRHCSRFRTLVAHYTPVQVLFEKGNLTVDTQKILKGSLISCIQEGLISGSQFWSASKTLKVLLEEEYFKENQNTESGCVLPSVIKSLTSESDSLGLTPGENSELALSALGGIVFYLKKCLIDQELLSLANFEKYIPVDADNAKTVSSSNFFARTDRRMVLDGVTLMNLEVLQNGTNGTTEGTLLERIDSCCTPFGKRLLKQWLCAPLCNPTSINDRLDAVEDLLAVPAKLTEITEHLKKLPDLERLLSKIHSIGSPLKSQNHPDSRAIFYEEIKYSKKKIADFLSALEGFKVMNEIVDAMEEVASDFKSQVLKQLVTRKAKHPDGRFPDLSAELKRWDTAFDHNQARKTGVITPKAGFDPDYDKALQDIKTVEEDFRTYLDKQRKLLGLKSVLYWGTGKNRYQMEIPETATSRNLPEEYELKSTRKGYKRYWTKEIEKMLAELINAEERRDAALKDCMRRLFYNFDKNSQDWQTAVQCIAVLDVLMSLANYSQDGDGPLCRPVILLPVDSAPPFLELKNARHPCITKTFFGDDFIPNDIVIGSKDEDGGSEASCVLVTGPNMGGKSTLMRQAGLLVIMAQLGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETSSILQHATEHSLVLVDELGRGTATFDGTAIASAVVRELAENIKCRTLFSTHYHSLVEDYSGSAAVRLGHMACMVENESEDPSQETITFLYKFIEGACPKSYGFNAARLADIPEEIIQKGHRKAKEFEKKTMSLRIFRFLCRVVDGVTHDANAVGKLTTMLSHL
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Involved in B cell growth by positively regulating B cell proliferation and controlling replication efficiency.  Controls cell cycle to prevent re-replication and defects in DNA damage-induced G2 checkpoint.  Doesn't seem to counteract or control the immunoglobulin gene conversion (Ig GC) and to contribute to guanine/uracil mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein Msh6.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GUAAA_PYRFU
Sequence: MIIIMDNGGQYVHRIWRTLRYLGVEAKIIPNTTPLDEIKAMKPKGIIFSGGPSLENTGNCEKILEHYEEFNVPILGICLGHQLIAKFFGGEVGRGEKAEYSLVEIEIIDENDIFKGLPRKVRVWESHMDEVKKLPPKFKLLARSDTCPVEAMKHEELPIYGVQFHPEVAHTEHGADILRNFAKICGEL
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit A, Glutamine amidotransferase.
Protein: GRLE_DICDI
Sequence: MKIKIGNILKNVVILVIFSLFISKINSEVVKPNPAKPDELVIAFMSPYFDPEYTQYSGAAEYALSKFNETFKTKYSKTIKLHTFTDTNDVIDSLDLVTMPVNGIVGPAYSGSSSTACLVFGAFAVPSISFYATGASLSNSGSYPYFQRVMPDDRLQVQAILSLLKKNGWTRVSCIHTNEDYGNGGADQLVQQSNAQGITVNTNQAIDPVDNGIAPEQLYYDIVFDNLEAAKSRVIVLYALFPPDCLEIWKQAKARGFLGEGFTWIVTDGCAELTGGTDPDLLGVLATFPSYGLGTEAYTDFERTIVNDYNNNTGDAFYKGASFSYDATYAMLMGIEAVLAKGGDPWDGEQVRTELRNLKFNGITGTIAFDKNTGDRLYGEFALLNLINSTKGSFDPIGKINPDSGEITLKSDILYSGPTYKVPSDYQVVVFDRTLNIVLGVITGVCVLIVIGIGSVIALQWRKFRYSSPLFCMFIIIGALMGLASVFTLLPTPTTPLCSGFPWLLGLGYVIVFGTLFTKTWRTWRLFSNARKFKIIRITNKFIITLVGGFVLLESIFMIIWTAVDRPIPLAEPIFKAGEAQLQCTSDSEAWWYVFVFYKVFYILFGVFLAFKTRNVVDSLNESKPITLALYNLTFVMVVAIALGFILRDNPIAIIVIQTIAILLGFTVTVSVLFLPKVWMILSGQQHSMDSIGTSMDSMGRSNGNTTEAESTRGYTNKDYNNQSVGRSFSAHATGFKDVAPSNHPQLGIVYTGGDNFPRVGSSQTAASRSEAEINVSKDVLAKANKKNEEEFGEFFLKPSEDNILKKKKKKKNNNK
What is the function of this protein?
May be involved in early development in cAMP sensing and subsequent chemotactic response.  Probable receptor of GABA and glutamate, leading respectively to the induction or inhibition of SDF-2 formation.
What are the official names of this protein?
Metabotropic glutamate receptor-like protein E, DdmGluPR, GABA-B receptor-like protein grlE.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: CDIA4_ECO5C
Sequence: MVNATLSVVQKNSAFVGSATGELAARAIGMLYPGVKQSDLSEEQKQTISTLATVSAGLAGGLTGSSTASAAVGAQSGKNAVENNYLSTNQSLTFDKELSDCRKSGGNCQDIIDKWEKISDEQSAEIDQKLKDNPLEAQVIDKEVAKGGYDMTQRPGWLGNIGVEVMTSDEAKAYVQKWNGRDLTKIDVNSPEWTKFAVFASDPENQAMLVSGGLLVKDITKAAISFMSRNTATATVNASEVGMQWGQGNMKQGMPWEDYVGKSLPADARLPKNFKIFDYYDGATKTATSVKSIDTQTMAKLANPNQVYSSIKGNIDAAAKFKEYALSGRELTSSMISNREIQLAIPADTTKTQWAEINRAIEYGKSQGVKVTVTQVK
What is the function of this protein?
Expression of this locus confers protection against other bacteria carrying the locus.
What are the official names of this protein?
Deoxyribonuclease CdiA-o11, DNase CdiA, CdiA-o11-EC869, Toxin CdiA.
What are the subcellular locations of this protein?
Target cell, target cell cytoplasm. Note=Toxin translocation into the target cell depends on the proton motive force of the target cell, but not on tolA or tonB.
Protein: NQRA_NEIMB
Sequence: MIKIKKGLNLPIAGRPEQAVYDGPAITEVALLGEEYAGMRPSMKVKEGDAVKKGQVLFEDKKNPGVVFTAPASGKIAAIHRGEKRVLQSVVIAVEGNDEIEFERYAPEALANLSGEEVRRNLIQSGLWTALRTRPFSKIPAVDAEPFAIFVNAMDTNPLAADPTVIIKEAAEDFKRGLLVLSRLTERKIHVCKAAGADVPSENAANIETHEFGGPHPAGLSGTHIHFIEPVGANKTVWTINYQDVITIGRLFATGRLNTERVIALGGSQVNKPRLLRTVLGAKVSQITAGELVDTDNRVISGSVLNGAITQGAHDYLGRYHNQISVIEEGRSKELFGWVAPQPDKYSITRTTLGHFLKNKLFKFNTAVNGGDRAMVPIGTYERVMPLDILPTLLLRDLIVGDTDSAQALGCLELDEEDLALCSFVCPGKYEYGPLLRKVLETIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.