PharMolix/UniProtQA huggingface dataset:
Protein: AFG1L_MOUSE
Sequence: MAASWSPLVTLRSAARSRLTGRGVGCGARVVAIPPPAPGPGKPLWKAYTVQTSEGVRPTAASEARLKALAVCHGPLDHYDFLIKSQELREDEHQRRVVQCLQKLQEDLKGYSIEEGGLFSKLFSRNKPPKGLYVYGDVGTGKTMVMDMFYAYVETKRKKRVHFHGFMLDVHRRIHHLKQSLPKRKAGFMAKSYDPIAPIAEEISQETSLLCFDEFQVTDIADAMILKQLFENLFKNGVVVVATSNRPPEDLYKNGLQRANFVPFIAVLKEYCDTLQLDSGVDYRKRELAPAGKLYYLTSEADVEAVVDKLFDELAQKQNDLTSPRILKVQGRELRLNKACGSVADCTFEELCERPLGASDYLELSKNFDTVIIRNIPQFSLAKRTQARRFITLIDNFYDFKVRIICSASAPISSLFLHQHQDSESDQSRILMDDLGLSQDSAGLSMFTGEEEIFAFQRTISRLTEMQTEQYWIEGDRSRK
What is the function of this protein?
Putative mitochondrial ATPase.  Plays a role in mitochondrial morphology and mitochondrial protein metabolism.  Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and normal activity of complexes III and IV of the respiratory chain.  Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress.
What are the official names of this protein?
AFG1-like ATPase, Lactation elevated protein 1.
What is the protein family that this protein belongs to?
Belongs to the AFG1 ATPase family.
What are the subcellular locations of this protein?
Mitochondrion membrane.
Protein: P160B_ARATH
Sequence: MFSPQ
What is the function of this protein?
Regulatory peptide encoded by the primary transcript (pri-miR160b) of the microRNA miR160b that enhances the accumulation of its corresponding mature miRNA.  Acts probably as a transcriptional activator of its corresponding pri-miRNA.
What are the official names of this protein?
Peptide encoded by miPEP160b.
Protein: TVP18_COCIM
Sequence: MSLAEEFKSRNFSIYGQWTGVICIILSFAIGLASVFSRFIVFGIISLVYSPLLLFIEVPFLLRICPTSSKFDAFIRRFTTNFMRAAIYAAMSGGLWISLVIDPSSLIAVAVFLAIAGLFYLLAALMKQEFTSSKTLGGQGVAQMIV
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein TVP18.
What is the protein family that this protein belongs to?
Belongs to the TVP18 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: YHBP_ECOUT
Sequence: METLTAISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFYILTEEKTRHAQMSGPQAAIAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARKAYNRRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRNSGTEQA
What are the official names of this protein?
UPF0306 protein YhbP.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: ARMX2_MOUSE
Sequence: MSRARDAGCVAAGIVIGASAWYCVYKYTRGKDQKKKRLTKPKNRASVGTGSRARAGLRAGFTIDLGPGFSPPNPVDIEIMNKAQGEASNLATTVAEEVAPAAPSPKVQNGAESKVQELNGAKTEANLESVVMPSATCTVTPPPKVAGGLTAAEAPEIIGAPKVLEAPSTTEASGAVAAPGPTVSPMIAQTPGPVVPSPTIVSTGPAAIPWAVAHPGAVQSPGPAVPPMAVQSLVPAAPSWAVVAPPGAVYIPVAAHFAGPAAASRVTQSPGTVIPPLPPPSSVLPRGVPSVPGRTVQSPGAAVHPVAAQSTGVVVPPRAVQYSGAAVTSGGAAVPSGGAATPRAAASTQRTASTEVMQVPRVAAATEATETPRIGTPAMVAEASLPVHSGAAENPGTSGSSKTAATGKKAAPGAHTGAIPKAGSATGAVPKGGGGKGGNKNRSGGKGKNRKNKVDVDELGMGFRPGDGAAAAAAASANGGQAFLAEIPESEEGESGWTDTESDSDSEPDVPQRGKGKRTIPMHKRPFPYEIDEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQGRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDMLKKLLGTQVPSSFSSLYNSYVESEILINALTLFEIIFDNLRAEVFNYREFNKGSLFYLCTTSGVCVKKIRALANHHDLLVKVKVIKLVNKF
What is the function of this protein?
May regulate the dynamics and distribution of mitochondria in neural cells.
What are the official names of this protein?
Armadillo repeat-containing X-linked protein 2.
What is the protein family that this protein belongs to?
Belongs to the eutherian X-chromosome-specific Armcx family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion outer membrane; Single- pass membrane protein.
Protein: NRDR_EDWI9
Sequence: MHCPFCSAVDTKVIDSRLVGDGSQVRRRRQCLVCNERFTTFEVAELVMPRVVKSNGVREPFNEDKLRSGMLKALEKRPVNSDDVEMAISHIKSQLRATGEREVATKMVGNLVMDALKKLDKVAYIRFASVYRSFEDVREFGEEIARLQE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: CNGC5_ARATH
Sequence: MAGKRENFVRVDDLDSRLPSSSVAFQQNYASNFSGQLHPIHASNETSRSFKKGIQKGSKGLKSIGRSLGFGVYRAVFPEDLKVSEKKIFDPQDKFLLYCNKLFVASCILSVFVDPFFFYLPVINAESKCLGIDRKLAITASTLRTFIDVFYLAHMALQLRTAYIAPSSRVFGRGELVIDPAQIAKRYLQRWFIIDFLSVLPLPQIVVWRFLQSSNGSDVLATKQALLFIVLVQYIPRFLRVLPLTSELKRTAGVFAETAWAGAAYYLLLYMLASHIVGAFWYLLALERNDACWQEACIDAGNCSTDFLYCGNQNMDGYAVWNRAKESVLKSKCRADLDDNNPPFDFGIYTQALSSGIVSSQNFIVKYCYCLWWGLQNLSTLGQGLETSTYPMEIIFSISLAISGLILFALLIGNMQTYLQSLTIRLEEMRVKRRDSEQWMHHRMLPQDLRERVRRYDQYKWLETRGVDEEYLVQNLPKDLRRDIKRHLCLALVRRVPLFKSMDDKLLDAICMRLKPCLFTESTYLVREGDPVDEMLFIIRGRLESVTTDGGRSGFFNRSLLKEGEFCGEELLTWALDPKSGVNLPSSTRTVKALTEVEAFALTSEELKFVASQFRRLHSRQVQHTFRFYSHQWRTWAACFIQAAWRRYCKRKKMEEAEAEAAAVSSSTAGPSYSIGAAFLATKFAANALRTIHRNRNTKIRDLVKLQKPPEPDFTAD
What is the function of this protein?
Probable cyclic nucleotide-gated ion channel.
What are the official names of this protein?
Probable cyclic nucleotide-gated ion channel 5, AtCNGC5, Cyclic nucleotide- and calmodulin-regulated ion channel 5.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MDG1_YEAS2
Sequence: MQSSLPQFTFKWPKGPEAIILTGTFDDWKGTLPMVKDPSGAFEITLPVTFDSPSSKFYFKFIVDGQWLPSKDYKVNIDEGVENNFITEEDVIKQRENGSSTLVPESAGLAVSKNAPLIEPEAEKRAKKLRKFKIKRVIKTNKQTGERSIFSQEVVELPDSEDETQQVNKTGKNADGLSGTTTIIENNVGVNEEKAIKPYEENHPKVNLVKSEGYVTDGLGKTQSSESRLYELSAEDLEKEEEEEDEDKGGGKDTSTSADAEASEDQNKEPLSKSAKFEKPEEKVPVSSITSHAKETSVKPTGKVATETQTYETKQGAPTAAAKKIEAKKATRPSKPKGTKETPYKGVQKNPAKNGGFFKKLAQLLK
What is the function of this protein?
Involved in G-protein mediated signal transduction and in the regulation of polarized cell growth in pheromone-induced cells.
What are the official names of this protein?
Signal transduction protein MDG1, Multicopy suppressor of defective G-protein 1.
What is the protein family that this protein belongs to?
Belongs to the CRP1/MDG1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MGP_PONAB
Sequence: MKSLVLLAILAALAVVTLCYESHESMESYELNPFINRRNANIFISPQQRWRAKVQERIRERSKPVHELNREACDDYRLCERYAMVYGYNAAYNRYFRERRGAK
What is the function of this protein?
Associates with the organic matrix of bone and cartilage.  Thought to act as an inhibitor of bone formation (By similarity).
What are the official names of this protein?
Matrix Gla protein, MGP.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSAA_CYAPA
Sequence: MRISPPEREAKKVKIVIDKDPVSTSFDKWAVPGHFSRTLAKGPKTTTWIWNLHADVHDFDSYTSDLEDVSRKIFSAHFGHLAVVFIWLSGAYFHGARFSNYEAWLSNPTTIKPSAQVVWPIVGQEILNGDVGGGFQGIQITSGLFQMWRASGITTELQLYVTAIGALVMAALMLFAGWFHYHKAAPKLEWFQNAESMMNHHLAGLFGLGSLSWAGHQIHVSLPVNKLLDSGVSPQEIPLPHEFILNKDLIAQLYPSFGQGLTPFFTLNWNEYSDFLTFKGGLNPVTGGLWLSDRAHHHLAIAVLFIVAGHMYRTNWGIGHSMKEMLETHKGPFTGEGHKGLYEIFTNSWHAQLSLNLALFGSLSIIVAHHMYSMPPYPYLATDYATSLCLFTHHVWIGGFLIVGAGAHAAIFMVRDYDPAQNYNNLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMRALGRPQDMFSDAAIQLQPVFAQWVQGVNSAAAGNTAPNALRNASYAFGGDIVSVGEKVAMMPISLGTADFLVHHIHAFTIHVTVLILLKGVLFARNSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSLSVVLFHFSWKMQSDVWGNVTADGAVSHITGNNFAQSSITINGWLRDFLWAQASQVIQSYGSALSAYGLMFLGAHFIWAFSLMFLFSGRGYWQELIESIVWAHNKLKFAPSIQPRALSITQGRAVGVAHYLLGGIATTWSFFHARIISVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, cyanelle thylakoid membrane; Multi-pass membrane protein.
Protein: FLGI_SHIFL
Sequence: MIKFLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGNTLNLQLNDEDFSMAQQIADTINRVRGYGSATALDARTIQVRVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLRAKLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: ECPE_ECO27
Sequence: MFRRRGVTLTKALLTVVCMLAAPLTQAISVGNLTFSLPSETDFVSKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFYYHGPRDNRERYYRVSFREVPTRNLTKRSPTGGEVSTEPVVVMDTILVVRPRQVQFKWSFDQVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPGDVVHQPELRQPGNHYLVYNDKFIKISDSCPAKPPSAD
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity).
What are the official names of this protein?
Probable fimbrial chaperone EcpE.
What is the protein family that this protein belongs to?
Belongs to the EcpB/EcpE family.
Protein: RS19_ASHYP
Sequence: AVILKAIKXNPKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SPEH_SYNWW
Sequence: MQSLGRHVLAEIYGCRFEVLNDVKKVEDIMVNAALEAGAEIREFVFHKFSPQGVSGVVVISESHLAIHTWPELGYAALDVFTCGDRVNPWDACNYVAEMFSAGDMKASEVKRGLMEQPEERLVANM
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: UBA3_PONAB
Sequence: MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVVAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSPSAKLQEVLDFLTNSASLQMKSPAITATLEGKNRTLYLQSVTSIEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS
What is the function of this protein?
Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme.  E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP.  E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M.  Down-regulates steroid receptor activity.  Necessary for cell cycle progression.
What are the official names of this protein?
NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1C, Ubiquitin-activating enzyme E1C, Ubiquitin-like modifier-activating enzyme 3, Ubiquitin-activating enzyme 3.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
Protein: RL15_FLAJ1
Sequence: MNLSNLQPAEGSTHNQNKRVGRGEGSGKGGTAARGHKGAKSRSGYSKKIGFEGGQMPLQRRVPKFGFKNINRKEYEGVNLDTLQLLVDNGVITDSVSMTDFVANRLASKNEIVKILGRGELKAKLKVTAHKFTATAKAAIEAAGGEAVTI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: NAGS_COPC7
Sequence: MIPRAPPSTQLFSAKTAVNQRSQTFKAFYATIRSLRQPPPEPPESPQAADNDFILSILKANPSLRDTRSYLASFGVQPQRPKTLEDKKLPEIVIPPPPAPKLTASSTKVVKEEKHAPSPVINSILNPIYRRTALVKIQGPFTDVQLDSITRGLVYLEKLGMVSVIVVESDGVPKGEQEERKLLIDEIMRVVTSLEKQGAHARPIVGAVVRLGPKPGSEEESEPGFSPPETHIYPSDLTPIRSSLRAGEIPVLAPFALDSRCRSVRVDANDAIAGLACGMVEAASENPSPAAHEDGSSDSDAIDLTPLRLMIINQRGGVPSYARSGYPHLLINLQQEYDHILQTFDPRWKDSHPHALSDLALARTCLRYMPPTSSAIMVSHKSPSSLIGNLITNKPAVSSSLPHALLQGNLRLTPHTPTLLRRGLPIRVVRSVSDIDKEKMTALLEQSFGRVLDQEAFYGRLEKTLDFVIIAGDYDGTAIVTNEVCPGSSQPISYLDKFAVLPSHQGDGTVDFLWVALHDESYGLGHPFSANPNGGKGGKGEGRDLVWRSRSNNPVNKWYFERSTGHLRMGQWVLFWADAEKRLKVEESLRGSAGLSFIEDWEHGRLGKWADTITKIPSSWK
What is the function of this protein?
N-acetylglutamate synthase involved in arginine biosynthesis.
What are the official names of this protein?
Amino-acid acetyltransferase, mitochondrial, Arginine-requiring protein 2, Glutamate N-acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CHP3_XENLA
Sequence: MGLSHSHSVETRELVEKTGFSAEQIEHLHKRFKSLSGDEPTIRRGHLNDISDLVLNPIRSKIIDAFFDKRNLRKGPSGYVEEINFEEFLIIMSYFRPLSQHMDEENISVCRTDKLRFLFNMYDSDNDNKITLEEYRKVVEELLSGNPNIEKEMARSIADGAMLEAASICVGQMEPDQVYEGITFDDFLKIWEGIDIETKMHIRFLNMESIPSCR
What is the function of this protein?
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity.  Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage.  Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation.  Also involved in granulocytic differentiation in a ERK-dependent manner.  Inhibits the phosphatase activity of calcineurin (By similarity).
What are the official names of this protein?
Calcineurin B homologous protein 3, Tescalcin, TSC.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family. CHP subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Membrane; Lipid-anchor. Cell membrane. Cell projection, lamellipodium. Cell projection, ruffle membrane.
Protein: LGT_CHLCV
Sequence: MRIFLSAIYWNHSKFLWNSENWPIKVPWYGLCFSLGILFASLLGIYLAKSSYNSEDEKNFSKEQLSGALENFALYSLLFIIPGSRIAYILFYGGDFYFKHPREILKVWNGGLASHGGMLGLILWALIFSWRYRKKISVLTFLFLCDLCASVFGCAAFMIRIGNFMNQEIVGKPTSLPWGIIFSSPAQGVLGVPVHPVQLYEGMSYLLLSIILFFLSYKRYFRLGSGWVTSLGLVGISLIRFFAEFFKSHQGKVIGPNSPLTMGQILSFPLFVFGLCLGIACFLKNKKKRSPTSSVK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: STCT_EMENI
Sequence: MPFGTLYTRPFNPRSLAILAIAKANNLPLKIKTITSFKDATEEYLQLNPLGKIPTFVGADGYVLTESIAIALYDSNTTLLGTTGQEYASIIRWMAFGITEILPALGGWFNPLIGRANFNADNIYQSKDDTLARLKILDNHLCGREYLVGETLSLADLFVLGIVQGAFRFFLDKRWRDEHRNLSTWFERVHALPIVVDVAGPPVLAEYEMPIQPPK
What is the function of this protein?
Glutathione S-transferase; part of the gene cluster that mediates the biosynthesis of sterigmatocystin (ST), a polyketide-derived furanocoumarin which is part of the most toxic and carcinogenic compounds among the known mycotoxins (PubMed:8643646).  The first step in the biosynthesis of sterigmatocystin is the production of hexanoate by the fatty acid synthase (FAS) units stcJ and stcK (PubMed:8962148).  The polyketide backbone is assembled by the non-reducing polyketide synthase stcA by condensation of the starter hexanoyl-CoA and 7 malonyl-CoA extender units followed by cyclization and release of norsolorinic acid (By similarity).  Norsolorinic acid is the first stable intermediate in the biosynthesis of sterigmatocystin and is converted into averantin (AVN) by the ketoreductase stcE which reduces the hexanoate ketone to an alcohol (PubMed:8643646) (Probable).  Averantin is then oxidized into 5'-hydroxyaverantin (HAVN) by the cytochrome P450 monooxygenase stcF (PubMed:10618248).  5'-hydroxyaverantin is further converted to 5'-oxyaverantin (OAVN) by the 5'-hydroxyaverantin dehydrogenase stcG (PubMed:24957370).  The next step is the conversion of OAVN into averufin (AVF) which is catalyzed by a yet to be identified enzyme (PubMed:24957370).  The cytochrome P450 monoxygenase stcB and the flavin-binding monooxygenase stcW are both required for the conversion of averufin to 1-hydroxyversicolorone (PubMed:10618248).  The esterase stcI probably catalyzes the formation of versiconal hemiacetal acetate from 1-hydroxyversicolorone (PubMed:24957370).  The oxydoreductase stcN then probably catalyzes the biosynthetic step from versiconal to versicolorin B (VERB) (PubMed:24957370).  The next step is performed by the versicolorin B desaturase stcL to produce versicolorin A (VERA) (PubMed:8999832).  The ketoreductase stcU and the cytochrome P450 monooxygenase stcS are involved in the conversion of versicolorin A to demethylsterigmatocystin (PubMed:7486998).  The Baeyer-Villiger oxidas stcQ and the reductase stcR might be involved in the biosynthetic step from versicolorin A to demethylsterigmatocystin (PubMed:24957370).  The final step in the biosynthesis of sterigmatocystin is the methylation of demethylsterigmatocystin catalyzed by the methyltransferase stcP (PubMed:8900026).
What are the official names of this protein?
Glutathione S-transferase stcT, Sterigmatocystin biosynthesis cluster protein T.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
Protein: TV23C_HUMAN
Sequence: MLQQDSNDDTEDVSLFDAEEETTNRPRKAKIRHPVASFFHLFFRVSAIIVCLLCELLSSSFITCMVTIILLLSCDFWAVKNVTGRLMVGLRWWNHIDEDGKSHWVFESRKESSQENKTVSEAESRIFWLGLIACSVLWVIFAFSALFSFTVKWLRRSRHIAQTGLKVLGSRDPPASAFQSAGITGVSRCPGHPSRKFHQVDINSFTRITDRALYWKPAPRLSSPPLRAAPGNCQQMAPARLFLSLRLWAWRGGGESPNSRGTGEPGPKFHLASGMH
What are the official names of this protein?
Golgi apparatus membrane protein TVP23 homolog C.
What is the protein family that this protein belongs to?
Belongs to the TVP23 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PROF_TETPY
Sequence: MSGWDQYVQYLTANQQVEYGLILGKTDGTIWASNVGLTTLYNNYQIDVEGQKANVNETANLLAAMNNNGVPTDPLCGIRIMNQKYYTVKYDADSQVWYLKKDHGGACIAITNQALVIGTFDITKKQQNGVAQNPGQVNKVVESLAATLKQAGY
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y808_GEOKA
Sequence: MLYLHDIWVNWFEGEENGYNVCHFHEWRKDDQIELLDQVPLLKVSPALFHYIENSLSDLPKPLLDDVHQKAYVRKNHERIQLDYCFVVTDGAGVLAVDTIGYQIPIRKSRLIPRQEQLVYEMAAEAEERDYPLPRYEKEYHILSPAPELMCGLTRKERQLKQLLFMALDQLYSTKNTAQMRYWYTEWAPEKYAAIQKMSFDEAWEQLYNETKYGWSERHEQLCENLIKGQPFFEKLWEMEQEPKVN
What are the official names of this protein?
UPF0736 protein GK0808.
What is the protein family that this protein belongs to?
Belongs to the UPF0736 family.
Protein: Y656_COXBU
Sequence: MIGGKFNLGSLMKNAKKIQEMMQKAQDELAKIRVTGESGAGMVKLTMTAQHEVVEMNLDDELLKESKEVIEDLIKAALNDANQKILKITQEKMMSAGSLFGGNESDNEET
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein CBU_0656.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MAFA1_TOXGO
Sequence: MWRIWRCRLSFLFATGCLLGALTAGLGSQMSDSVGRNVQAPAGVADASQEAGDVVEERTERTEEQVFAPGPPRRHSSESLFPRNASVTARRRRNRRIAPIATAVGVAVILAALYVLRRRRAQPPQEPEPPTRLRTPRPRAPSEQQQPSESEPPAEVPMTPDPLTLRFTCLGDRNVIFFGPSGRQDGFTPLYDPSPSKRVATVDAGTYGLFIGGVGMNGEFADTIIEEARRNRIPLTATELSAESQEIQERLLHDAERQPGTLVEIDSGRFSRVFARSFAYVAIVPNTVWDESETGKNVGATFLHILKPEVTPHGNEMNDVMLYTVAPFGNASDSAYNMAYKATMLGIVGAVSEYNKTPWGEVKPVEAIRLPLLGAGHFRGRRGLHSIGRANAVAVEAAITRFDPRVELQFMYEPSDTALRGLMESERKYKFPQGD
What is the function of this protein?
During host cell infection by tachyzoites, does not play a role in tethering the parasitophorous vacuole to the host mitochondria, probably because it does not bind host mitochondrial import protein TOMM70.
What are the official names of this protein?
Mitochondrial association factor 1 form a1, MAF1RHa1 allele, MAF1a.
What are the subcellular locations of this protein?
Parasitophorous vacuole membrane; Single-pass type I membrane protein.
Protein: DYR_LACLA
Sequence: MIIGIWAEDEAGLIGEADKMPWSLPAEQQHFKETTMNQVILMGRKTFEGMNKRVLPGRISIILTRDETYQSDNEKVLIMHSPKEVLDWYHKQNKDLFITGGAEILALFESELELLYRTVVHEKFKGDTYFPSTFDFGRFKLVSEKFHDKDERNSYTFTIKKYEKVKQP
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: RL15_VIBC1
Sequence: MRLNTLAPAAGSKHAPKRVGRGIGSGLGKTGGRGHKGQKSRSGGKVRPGFEGGQMPLKQRLPKFGFTSRKSLVSAEVRLGELAKVSGDVVDLNSLKAANIITKNIEFVKVVLSGEINKVVTVKGLRVTKGAKAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: R34K_CLOPA
Sequence: MKEEKQLDLVIIGAGPAGLTAAIYAIRAKLNTLVLENELVGGQIRETYTVENFPGFNVISGADLADKMEEHAASIGVNIDQFSNIEKIKLSDDEKIIETEDVIYKVKALIIATGAKSRRLPIPEEEKLHGKVIHYCELCDGALYQGKDLVVVGGGNSAVEAAIFLTKYARNITIVHQFDYLQAQKYSQDELFKHKNVKIIWDSEIRNIVGENEIEKIVVENVKTKQKTELKADGVFVYIGYEPKTELFKDSININKWGYIETDENMETNIKGVFAAGDVRSKLIRQLTTAVSDGTVAALMAEKYIGGK
What are the official names of this protein?
34.2 kDa protein in rubredoxin operon, ORF A.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
Protein: COAD_STRPD
Sequence: MLTKIGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKKSYFKLEVRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEENLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEDLVPQSVIAQVEKMNEKT
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.