PharMolix/UniProtQA huggingface dataset:
Protein: COX1_PETMA
Sequence: MTHIRWLFSTNHKDIGTLYLIFGAWAGMVGTALSILIRAELSQPGTLLGDDQIFNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWLLPPSLLLLLASAGVEAGAGTGWTVYPPLAGNLAHTGASVDLTIFSLHLAGVSSILGAVNFITTIFNMKPPTMTQYQTPLFVWSVLITAVLLLLSLPVLAAAITMLLTDRNLNTSFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVAYYAGKKEPFGYMGMVWAMMAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGKIVWHTPMLWALGFIFLFTVGGLTGIVLSNSSLDIILHDTYYVVAHFHYVLSMGAVFAIMAGFVHWFPLFTGYTLNETWAKAHFIIMFAGVNLTFFPQHFLGLAGMPRRYSDYPDAYTTWNIISSIGSTVSLIAVMLFMFILWEAFSAKRKAIATDLLNTNLEWLHGCPPPYHTYEEPAFVQTNFKK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NUOK_CHLT3
Sequence: MEIELGHYLALSAFVFICGVLGVLTRRNAIIIFMSIELMLNAVNLSFVAFSHYLSDIAGQMMVFFVMTVAAAEAAVGLAIVISLFRNKQTVNIDEINLLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HLDD_ECOLI
Sequence: MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFTQADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: RS14_BUCAP
Sequence: MAKQSMKAREVKRVKLANKFYAQRIALKNTITNLKLSEEERWDAVLKLQIFPRDSSPSRQRNRCRQTGRPHAFLRKFGLSRIKVREAAMKGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: IXTPA_THEYD
Sequence: MKIVIASRNRKKIEELKRILQGLEITILSVNDFPELEEVKEDGLTFDENALKKARYVCQQTGLPALSDDSGLEVEALGGRPGVRSARYAGDEASDDDNIKKLLEELAGVPSEKRTAQFVCCIALVFPDGKEYIFWGYVRGKISEIPRGTQGFGYDPVFIPEGFKKTFAEMSPHEKDKISHRKEALDKLRDFLIKFAPIYKQNLL
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: KA273_LYCMC
Sequence: MKLMWLLFLCVLAFSIAQIYISDPCAGGVHRCYEPCEKKKCRLPHKCINGRCTCYVGRNVCAISSH
What are the official names of this protein?
Potassium channel toxin alpha-KTx 27.3, Putative neurotoxin-C.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 27 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NDK_ALTMD
Sequence: MALERTFSIIKPDAVAKNVIGAIYNRFESAGLRIVASKMIHMSKEQAEGFYAEHKERPFFGALVDFMTSGPVMVQVLEGENAVLANREIMGATNPADAASGTLRSDYAASIDENAVHGSDAPESAAREIAYFFSEEEICPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_BREBN
Sequence: MRISVKAPAKINLTLDVLAKRPDGYHEVEMVMTTVDLADRVDMTLREDGEITLDCSASFVPDDIRNHAYKAATLMKAKFQVRQGVHLYIDKQIPVAAGLAGGSSDAAATLRGLNQLWNLGLTRDELAKIGAEIGSDVPFCVYGGTALATGRGEQIAHLGAPAPCWVILAKPPIGVSTPDVYGNLRVAQIDNHPDTKQMLQAIATQDFSLMCQSLGNVLENVTLSLHPQVRQIKDLMIASGADGVLMSGSGPTVFALVQKEAKVHRIYNALRGFVKDVFVVRMLGAQEGEILA
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RS6_CHLTB
Sequence: MKKKTGQLYEGAYVFSVTLSEDARRKALEKVTSGITNYGGEVLKIHDQGRKKLAYTIRGAREGYYYFIYFTVAPEAIAELWREYHLNEDLLRFMTLKASAVKEVLEFATLPE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RELA_ECO57
Sequence: MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
What is the function of this protein?
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.  This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity).
What are the official names of this protein?
GTP pyrophosphokinase, (p)ppGpp synthase, ATP:GTP 3'-pyrophosphotransferase, ppGpp synthase I.
What is the protein family that this protein belongs to?
Belongs to the RelA/SpoT family.
Protein: REL3_RAT
Sequence: MATRGLLLASWALLGALVLQAEARPAPYGVKLCGREFIRAVIFTCGGSRWRRADILAHDPLGEFFADGEANTDHLASELDEAVGSSEWLALTKSPQVFYGGRSSWQGSPGVVRGSRDVLAGLSSSCCEWGCSKSQISSLC
What is the function of this protein?
May play a role in neuropeptide signaling processes.  Ligand for LGR7, relaxin-3 receptor-1 and relaxin-3 receptor-2 (By similarity).
What are the official names of this protein?
Relaxin-3, Insulin-like peptide INSL7, Insulin-like peptide 7, Prorelaxin R3.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FBIB_MYCBO
Sequence: MTGPEHGSASTIEILPVIGLPEFRPGDDLSAAVAAAAPWLRDGDVVVVTSKVVSKCEGRLVPAPEDPEQRDRLRRKLIEDEAVRVLARKDRTLITENRLGLVQAAAGVDGSNVGRSELALLPVDPDASAATLRAGLRERLGVTVAVVITDTMGRAWRNGQTDAAVGAAGLAVLRNYAGVRDPYGNELVVTEVAVADEIAAAADLVKGKLTATPVAVVRGFGVSDDGSTARQLLRPGANDLFWLGTAEALELGRQQAQLLRRSVRRFSTDPVPGDLVEAAVAEALTAPAPHHTRPTRFVWLQTPAIRARLLDRMKDKWRSDLTSDGLPADAIERRVARGQILYDAPEVVIPMLVPDGAHSYPDAARTDAEHTMFTVAVGAAVQALLVALAVRGLGSCWIGSTIFAADLVRDELDLPVDWEPLGAIAIGYADEPSGLRDPVPAADLLILK
What is the function of this protein?
Bifunctional enzyme that catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
What are the official names of this protein?
Bifunctional F420 biosynthesis protein FbiB.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the CofE family.
Protein: GCSPB_BACC1
Sequence: MKNQDQALIFEVSKEGRIGYSLPKLDVEEVKLEDVFESDYIRVEDAELPEVSELDIMRHYTALSNRNHGVDSGFYPLGSCTMKYNPKINESVARFAGFANIHPLQDEKTVQGAMELMYDLQEHLIEITGMDTVTLQPAAGAHGEWTGLMLIRAYHEANGDFNRTKVIVPDSAHGTNPASATVAGFETITVKSNEHGLVDLEDLKRVVNEETAALMLTNPNTLGLFEENILEMAEIVHNAGGKLYYDGANLNAVLSQARPGDMGFDVVHLNLHKTFTGPHGGGGPGSGPVGVKADLIPYLPKPILEKTEDGYRFNYDRPEAIGRVKPFYGNFGINVRAYTYIRSMGPDGLRAVTEYAVLNANYMMRRLAPFYDLPFDRHCKHEFVLSGRRQKKLGVRTLDIAKRLLDFGYHPPTIYFPLNVEECIMIEPTETESKETLDGFIDKMIQIAKEVEENPEVVQEAPHTTVIKRLDETMAARKPVLRYEKPAPVQV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: ENO_PROM3
Sequence: MIDSLDLVIDTIVAREVLDSRGNPTVEAEVLLEAGAIGRAIVPSGASTGAHEAHELRDGDSRYMGKGVTKAVNHIEDRIAPALCGISSLDQASVDGTMQELDGSDNKSSLGANAILAVSMATARAAANGLGLPLYRYLGGPMASLLPVPLMNVINGGAHAANNLDFQEFMLVPHGASTFRESLRMGAEVFHTLKGLLSAQGLSTAVGDEGGFAPNLTNNDAAGDLLIQAIEKAGYSPGKDISLALDVASTEFYKDGCYAFGGGSYTSTEMVNELEKLVDRYPIISIEDGLAEDDWQGWALLTKKLGKRIQLIGDDIFVTSTKRLQQGIDQNVANSILIKVNQIGSLTETLQAIDLAGRSGYTSVISHRSGETEDTTIADLAVATRAGQIKTGSLSRSERVAKYNQLLRIEDELGTQALYAGATGQGPRGRS
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SIX6_BUTOC
Sequence: DGYPKQKNGCKYDCIINNKWCNGICKMHGGYYGYCWGWGLACWCEGLPEDKKWWYETNKCGR
What is the function of this protein?
Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis.  They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.  This toxin is active only on insects.
What are the official names of this protein?
Beta-insect depressant toxin BotIT6, Insect toxin 6.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GRTP1_XENLA
Sequence: MDEANQIAKDSVPRIDAYGFIRPVEFDYAVYEEFIARYRVVLTRRALKWSKLLQQSAAVEKSIKVKRYIRKGIPNEHRSHVWMVVSGAQAQMGMNTGYFRRMFIEGEKNPKLLDLVNTDLNRTFPDNVQFRKNSNPSLQKHLYNVLVAYGQHNTTVGYCQGMNFIAGYLILVTKDEEKAFWLMDALIGRILPDYYSPAMTGLKTDQEVLGDLVKKKLPAVSQLIEAHGVMWTLLVSRWFICLFIDILPVETVLRIWDCLFFEGSKVLFRVALTLIKQYQAFILEARNFPDICDKFKEITKGEFVTDCHYFMQKIFAEPGSLSKTTIDKLREKQRLQLASEEK
What is the function of this protein?
May act as a GTPase-activating protein for Rab family protein(s).
What are the official names of this protein?
Growth hormone-regulated TBC protein 1.
Protein: GAR1_NEOFI
Sequence: MSFRGGGRGGFASGANRGGNFGGRGGRGGFQAQTGPPAQVLEMGTFMHACEGEMVCESVNPKIPYFNAPIYLENKTPIGKVDEVLGPINQVYFTIKPQEGIVATSFKPGDKVYIGGDKLLPLEKFLPKPKPPPGSKPKKAVGGRGGFARGGARGGRGAPRGGRGGAPRGRGGPRGGGFGGGSFGGGGFRGGSRGGGRGGPRGGSGGFRR
What is the function of this protein?
Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.  The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs.  The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit gar1, snoRNP protein GAR1.
What is the protein family that this protein belongs to?
Belongs to the GAR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: R15PI_HALVD
Sequence: MDDRVHPEVRRTATEIDTMEIRGAATIADAAARALRTQATESDAADAEAFRAELRATARTLHETRPTAVSLPNALRYVLRDMSSTTVEGLRQSVVDSADEFCARLERAQADLGQVGANRLRDGDTIMTHCHSTDALACVEAAVEQGKHIEAVVKETRPRNQGHITAKRLHELGVPVTLIVDSAARRYLNDVDHVLVGADAVAADGSVINKIGTSGLAVNARERGTPIMVAAQTLKLHPGTMTGHTVDIEMRDTAEVVDDDTLADLGNPTVKNPAFDVTPPRYVDAIVTERGQFPPESIVILMRELFGEGTSEPWAEPSPRAEP
What is the function of this protein?
Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO.  Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
What are the official names of this protein?
Ribose 1,5-bisphosphate isomerase, R15P isomerase, R15Pi, Ribulose 1,5-bisphosphate synthase, RuBP synthase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
Protein: NQOR_BRUME
Sequence: MVKMLVLYYSAYGYMEQMAKAAAEGAREGGAEVTLKRVPELVPEEVAKASHYKIDQEAPIATPGELADYDAIIIGTATRYGMMASQMKNFLDQTGGLWAKGALINKVGSVMVSTATQHGGAELALISTQWQMQHHGMIIVPLSYAYREQMGNDVVRGGAPYGMTTTADGDGSRQPSAQELDGARFQGRRVAEITAKLHG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: KDSA1_PSEPK
Sequence: MTQKIIRVGNIEIANDKPFVLFGGMNVLESRDLAMKVCEEYVRVTEKLGIPYVFKASFDKANRSSVTSYRGPGMEEGLKIFEEIKRTFNVPVITDVHEPYQAEPVAKVCDIIQLPAFLSRQTDLVVAMAKTGVVINIKKAQFLAPQEMKHILAKCEEAGNDQLILCERGSSFGYNNLVVDMLGFGIMKQFEYPVFFDVTHALQMPGGRADSAGGRRAQVTDLAKAGMSQGLAGLFLEAHPDPDNAKCDGPCALRLDKLEPFLVQLKQLDDLVKSFPTVETA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase 1, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase 1, KDO-8-phosphate synthase 1, KDO 8-P synthase 1, KDOPS 1, Phospho-2-dehydro-3-deoxyoctonate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U2A2A_NICPL
Sequence: MRDYEGNGVDIDNNGASPYSQHISRDHENERDSSRSRDKERDKGRDKDRDRDRNRDRDRDRDRVKERDKDRHRDRDGEKDRDRHHRDRHRDRSDRRERERTRDRDEDDLHRSRDYDRRRDNDKDREDRRRHRPSSRGRSEHRSKSRSRSPSKSKRISGFDMAPPTTALLPGATDAAGQVPGTNPAIPGLFSNMFPLASSQFGALPMMPVQAMTQQATRHARRVYVGGLPPTANEQSVATFFSHVMYAIGGNTAGPGDAVVNVYINHEKKFAFVEMRSVEEASNAMALDGVIFEGGPVKVRRPSDYNPSLAATLGPSQPSPNLNLAAVGSTPGSSGGLEGPDRIFVGGLPYYFTESQIRELLESFGQLRGFDLVKDRETGNSKGYAFCVYQDVSVTDIACAALNGIKMGDKTLTVRRANQGTTQPNPEQESVLLHAQQQIALQRFMLQPGALATKVLCLTEVVTVDELNDDDDYQDILEDMRTECEKFGALVNVVIPRPNPNGVPTPGLGKVFLEYADVDGSSKARQGLNGRKFGGNQVVAVFYPENKFSEGDYEA
What is the function of this protein?
Necessary for the splicing of pre-mRNA.  Binds to the U -enriched regions of plant introns.
What are the official names of this protein?
Splicing factor U2af large subunit A, NpU2AF65a, U2 auxiliary factor 65 kDa subunit A, U2 small nuclear ribonucleoprotein auxiliary factor large subunit A, U2 snRNP auxiliary factor large subunit A.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FAC15_MYCTU
Sequence: MREISVPAPFTVGEHDNVAAMVFEHERDDPDYVIYQRLIDGVWTDVTCAEAANQIRAAALGLISLGVQAGDRVVIFSATRYEWAILDFAILAVGAVTVPTYETSSAEQVRWVLQDSEAVVLFAETDSHATMVAELSGSVPALREVLQIAGSGPNALDRLTEAGASVDPAELTARLAALRSTDPATLIYTSGTTGRPKGCQLTQSNLVHEIKGARAYHPTLLRKGERLLVFLPLAHVLARAISMAAFHSKVTVGFTSDIKNLLPMLAVFKPTVVVSVPRVFEKVYNTAEQNAANAGKGRIFAIAAQTAVDWSEACDRGGPGLLLRAKHAVFDRLVYRKLRAALGGNCRAAVSGGAPLGARLGHFYRGAGLTIYEGYGLSGTSGGVAISQFNDLKIGTVGKPVPGNSLRIADDGELLVRGGVVFSGYWRNEQATTEAFTDGWFKTGDLGAVDEDGFLTITGRKKEIIVTAGGKNVAPAVLEDQLRAHPLISQAVVVGDAKPFIGALITIDPEAFEGWKQRNSKTAGASVGDLATDPDLIAEIDAAVKQANLAVSHAESIRKFRILPVDFTEDTGELTPTMKVKRKVVAEKFASDIEAIYNKE
What is the function of this protein?
Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension.
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase FadD15, FACL, Acyl-CoA synthetase, FACL15.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: DNAJ_PARUW
Sequence: MADYYEILEVARGATPEEIKKAYRKKAVQYHPDKNPGDADAEKRFKEISEAYEVLSDEKKRQVYDRYGKEALQGAAGGGQGFSSMDEALRTFMGAFGMGGGGESIFDFFGGGNGAEFGGREGGRGARQGASKRVNINVSFEEAVKGVDKELVISNYANCNVCNGKGSSSSQGIKTCSECKGRGQVFEQRGFFSMTMACPKCHGEGKVITDPCKNCKGQGAVKEKQHIKVHIPAGVDSGMRLKMSGYGDVGQHGGPAGDLYVFINVEPHEIFEREGNDILLDLPISFAEAALGCKKEVPSLTNRACRITIPEGTQNGKIFRVKGEGFPNVHGHGKGDLLVRIFVETPTRLSERQKELLQEFSELEGPNNLPKRKGFLDKIKEFFSPN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H33_STYLE
Sequence: NTGGKAPRKHIAHKQAKKSSAAAATGGVKKPHRFRPGTVALREIRRFQKSTELLIRKLPFQRLVREIASEFKNDLRFQSSAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMP
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3-3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: LPXB_FRATT
Sequence: MRIGIVAGELSGDQLGGTLVEALKQKYPNAIIEGIGGPKMAAAGFKSLYPMDALSLIGFLEIISKGLRILSIRRKIINYFKQNKPDIFIGIDAPDFNLTVEKELRSAGIKTIHYVSPKIWVWREYRIKKIRKATDKILAILPFETEYYKNRHKFEAIYVGHPLAKNIPIHIDRAKYRDKLGLKGSSLPILSVLPGSRTTEVSRLLPLFLLALQKLVDAGYKFKAIMPLAKPSLKPLFAKYKEQIDSLGIEVFETNSHDVLKASDLSLLASGTATLEAMLCKLPMVVGYKLSWLSALIGRMLIGNHSYWAFPNILHKNEIIKELIQEDCTVDNLFSELKRLFDDKRRNDYIVEEFEKIHKEMVIDTESKIIQVLDTMIEKS
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: RBL_GOSHI
Sequence: MSPQTETKASVGFKAGVKEYKLTYYTPEYEVKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVPGEEDQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRVPTAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIFKSQAETGEIKGHYLNATAGTCEEMIKRAMCARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKAIKFEFEAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.