PharMolix/UniProtQA huggingface dataset:
Protein: FABH_DESHD
Sequence: MVSVGIVGTGSYVPDKVLTNFDLEQMVDTNDQWIVSRTGIKERHIAAPETPVSELCYQAALRALEDAKLAPEELDLVIVATITPDFVFPATACLVAERLGAKKAAGFDLQAACTGFLYGVATAAQFIATGIYKNALVIGGETLSKILNWEDRGTCILFGDGAGAAVLQPVEEGYGFLGYDLGMDGAGGSLLTMPGGGSMHPASAETVAKKMHTIQMAGSEVFKFAVRIMGETALKALDKAGLGIGDVDCLIPHQANTRIVDAAVKRLGIDAGKVVVNLDRYGNMSAASIPVALDEAARSGRLNYGDIMVMVGFGGGLTWGAAVVKWSKRGV
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPAT_DESPS
Sequence: MITINENYLKLQASYLFSDIAKRVATFQEENPEKEVIKLGIGDVTRGLTPSVIAAFHQAVDEMANDSTFHGYGPEQGYAFLREAIAENDFQSRGAGIVADEIFVSDGAKCDTSNIQEIFSAETKIAIPDPVYPVYLDTNVMAGRTGLFADGRYQNIVYLDSTKENNFVPELPTEKVDLIYLCFPNNPTGSTITKAGLKRWVDYAIENKALILFDAAYEAFIQDDTLPKSIYEIEGADKVAIEFRSFSKNAGFTGTRCAYTVVPKACMAYDSEGNSHSLHSMWNRRHCTKFNGVSYPIQRAAAATYTPEGKAECKELIDYYMANAKVVXSNHDKLGYSYVGGENSPYIWIDGKTDSWEFFDMLLSKAGVVCTPGAGFGTCCGNGYIRISAFNSPENIEKAMARITEALS
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: SURA_BORA1
Sequence: MMRRLHSSRRFSGSLLALALGLALPLAHAADKPAAGKPAASQPAASKPQGGEQFVDGIAAIVNKDVITMREVQDGVKRAKVDLKERGIQLPDDNVLQKQVLQRLIFDRLERQEADRLGIRVDDAQVTQAINMVASRNKLTPQQLRAEVEKNGLSWDDYRKSLREEIRTDRLRQRTIDNHIIITDAEVDAYLKDQARNPALQPQSAQAPVQEAPAAATGPVMLALGQILVRVPEGASPDTVASLRKKAEDILARLKRGDDFASVAAASSDGPEALEGGVMGVRPIDGWPDLFVKAVSNVPAGQVSGIIQSGNGFHILKVLQRGQAGAPAPARAAAPMPAPAAGRAAQGPVQVTQTHARHILIKTSAVMSDQQARQRLEQVRQRLESGSAKFEDMARQYSQDATAPQGGDLGWVNPGEMVPSFEAAMNSLKPGEISQPVESPFGWHLVQVLERRQKDVTDEMQRMQARQALFERRAGPAFEDWMEQLRAQAYIDNRLEKQERIEQNNR
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: ZEB2_GIBZE
Sequence: MQSTESFHALPTRSDVEDPNERRKIQNRIAQKKHRQKMKRRIEELETKVNNQCQTSNWTSHAPTDSCQEQQFLDNTDFGLMLEDDLLYRELSASLDGAGLTAVAQMHDSPRPNQQQRLSVSGMPSSPTSTSNVAQRGLSIGDHSSASNHLSSLSLVPGSTEGSLPTRQHDNLCNQDLRDMVPEEKMSRILKVIQDAGYKDMDSFMTEYYVRDFDASSHVSAVQRQSRSRRLRGFLEQLRVGAESWSDYEAHDYQQEISKSAEAIYAKELDVFSTTTLGENASFQGLASLYRVLQSTVGSDIENHLRHEQSMMQRQVSEIVHRQVYTFNPAQC
What is the function of this protein?
Transcription factor that specifically controls transcription of the zearalenone biosynthesis cluster genes (PubMed:16262793).
What are the official names of this protein?
Transcription factor ZEB2, Zearalenone biosynthesis protein 2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YOAH_ECODH
Sequence: MFAGLPSLTHEQQQKAVERIQELMAQGMSSGQAIALVAEELRANHSGERIVARFEDEDE
What are the official names of this protein?
UPF0181 protein YoaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0181 family.
Protein: MDHC_ORYSJ
Sequence: MAKEPMRVLVTGAAGQIGYALVPMIARGVMLGADQPVILHMLDIPPATESLNGLKMELVDAAFPLLKGIVATTDVVEACTGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKSQASALEAHAAPNCKVLVVANPANTNALILKEFAPSIPEKNITCLTRLDHNRALGQISEKLNVQVTDVKNAIIWGNHSSTQYPDVNHATVKTPSGEKPVRELVADDEWLNTEFISTVQQRGAAIIKARKQSSALSAASSACDHIRDWVLGTPEGTFVSMGVYSDGSYGVPAGLIYSFPVTCSGGEWTIVQGLPIDEFSRKKMDATAQELSEEKTLAYSCLN
What are the official names of this protein?
Malate dehydrogenase, cytoplasmic, PP37.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_CLOBL
Sequence: MDLFKFFSKQSSKDVAKERLKLILIQDRNSISPDVLESIREDMLKVISKYIEIDNEDVDIKMSSVEEIEGMSPALIASIPIKRIKKK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: MNMA_PAEAT
Sequence: MRVLAAMSGGVDSAVAAARAVEAGHDVVGVHLALSRMPGTLRTGSRGCCTIEDSRDAWRACDVLGIPYYVWDFSERFKEDVVQDFIDEYAAGRTPNPCMRCNERIKFAALLEKAIALGFDAVCTGHYAKVIEDADGNRELHRAADWAKDQSYVLGVLTHEQLKHSMFPLADTPSKAEVRAEAERRGLSVANKPDSHDICFISDGDTRGWLAEKIDMTTGDIVDETGAKVGEHPGANAFTVGQRRGLKLGTPAADGKPRFVLEIRPKENKVVVGPEALLAIDEIRGIKVSWAGLPISEVATGAEFDCHAQVRAHGDPVPAIARVEAVTDESGVERAQLVVTLTDPLRGVAPGQTVVLYQGSRVLGQATIDAARSLQRQVL
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_NEIG1
Sequence: MKRKNIALIPAAGIGVRFGADKPKQYVEIGSKTVLEHVLGIFERHEAVDLTVVVVSPEDTFADKVQTAFPQVRVWKNGGQTRAETVRNGVAKLLETGLAAETDNILVHDAARCCLPSEALARLIEQAGNAAEGGILAVPVADTLKRAESGQISATVDRSGLWQAQTPQLFQAGLLHRALAAENLGGITDEASAVEKLGVRPLLIQGDARNLKLTQPQDAYIVRLLLNAV
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: TIG_VESOH
Sequence: MKTSLETLKGLSRSLTIDLPIDIFNQKMDKILQKMALEVNIDGFRKGKVPISIVRKRFGNNANSDVINEIVNETLTDALAQVKLTPVAQPVITKVDSNSNKNFSYTVEFEVFPKIKIADFSELSIEQTKVNITKADEQKTLDGLKDRLTEYKAVQCKSKMGDRLSIDFKGLINGETFDGGEAKDFKIVLGKGSMIKGFEEGLIDVAYSSRVVLDLTFPKDYYMDKLASKDVTFEININEIASPKELKLDETFAKKFGEKNMNALRVSMKEQMRVEVDGRIGHLNKNAIFDKLTTANPFNVPQHSIDNEAQNLFKAMQDRMQHQGLSTQGEMPITAFNDEAQRRVKLGLLVNQISRDYKLSVSMKQIDEKLKEISKTYGENAQQMIDFYNQDPTRKSSIELLVVEKMVQDLILDKAQVTFKQKKFQEITQ
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: FA50B_MACFA
Sequence: MAQYKGTMREAGRAMHLLKKREKQREQMEVLKQRIAEETILKSQVDKKFSAHYDAVEAELKSSTVGLVTLNDMKARQEALIRERERQLAKRQQLEEQRLQQERLREQEHRRERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGQRKDFLELRSAGVEQLMFIKEDLILPHYHTFYDFIIAKARGKSRPLFNFDVHDDVRLLSDATMEKDESHAGKVVLRSWYEKNKHIFPASRWEAYDPEKKWDKYTIR
What are the official names of this protein?
Protein FAM50B.
What is the protein family that this protein belongs to?
Belongs to the FAM50 family.
Protein: Y1428_OCEIH
Sequence: MPDLMIDHREKAHALLKADADKILRLIEVQIENLTMPQCPVYEDVLDTQMYGLSREIDFAVRLELISEIEGKALLENLEKKLNILHEASQNTL
What are the official names of this protein?
UPF0358 protein OB1428.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: KTHY_FINM2
Sequence: MFITFEGPDGSGKSTIIQKVYDYLIENNYDVIKTREPGGSPIAEKIRNLILDTENIKMGYRTEALLYAASRAQHVEETILPALNENKIVLCDRFLISSLAYQGVGRGLGIENVRNINEFAINGVFPDFVLFFDVDPITTLKRKSSLDTADRLEKEGNNFHERVYNGYKEILNSEKNIEIIDATQSVEDVFSQCIEVLKRRNVL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: TMM92_MOUSE
Sequence: MLDTWVWGTLTLTFGLLSSLQGVSFNETANTCDILNCPKGFTCCVKECCPERKVWDPANDRFRFLVILACIIFPILFICALVSLFCPNCTELQHDVRRVDHQTPIEPPSIAPLESIWVTSLDPPPPYSQVVQMTPPTEPPPPYSLRPEGPAGQMRGRAYATL
What are the official names of this protein?
Transmembrane protein 92.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SPSB4_HUMAN
Sequence: MGQKLSGSLKSVEVREPALRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATARAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ
What is the function of this protein?
Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:21199876, PubMed:15601820).  Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (PubMed:21199876).  Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (PubMed:21199876).  Diminishes EphB2-dependent cell repulsive responses by mediating the ubiquitination and degradation of EphB2/CTF2 (PubMed:28931592).  Regulates cellular clock function by mediating the ubiquitin/proteasome-dependent degradation of the circadian transcriptional repressor NR1D1 (PubMed:26392558).
What are the official names of this protein?
SPRY domain-containing SOCS box protein 4, SSB-4.
What is the protein family that this protein belongs to?
Belongs to the SPSB family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol. Note=Exhibits a diffuse cytosolic localization.
Protein: MATK_PHODC
Sequence: MEELQGYLEKDRSRQQHFLYPLLFKEYIYTFVHDRGLNSSVFYESTEIFGYDNKSSSVLVKRSIIRMYQQNYLIYSVNDSNQNRFVGHNNYFYFHFYSQMILEGFAVIVEIPFLLRLVSSLEEKKIPKSQNLNLRSIHSTFPFLEDKLSHLNYVSDILIPYPIHLKILVQILQFWIQDVPSLHLLRFFLHEYHNWNSLITPNNSIFLFSKENKRVFRFPYNSYVSECEFVLVFLRKQSSYLRVTSSGAFLERTHFYGKIEHRIVVRRNYFQKTLWFFKDPFMHYVRYQGKAILVSKGTHLLMKKWKCYLVNFWQYYFHFWSQPYRIHINQLSNCSFYFLGYLSSVLINPSAVRNQMLENSFLIDTVIKKFDTRVPVITLIGSLSKAKFCTVLGHPISKPIWTDLSDCDINDRFGRICRNLSHYHSGSSKKQSLYRIKYILRFSCAXTLARKHKSTVRAFLQRLGSGLLEEFFMKEEQVVSLIFPKTTSFSLHESHIERIWYLDIIHINDLVNYS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YHG1_SCHPO
Sequence: MEYLTNLKTNIMDKQLGHREVSEGSTQPKPDPSGATMKACVWDGPLNVKIAEVPKPTITHPKDVIVKTTACTICSGSDSHIFSGEMPGIEKGAILGHESCGIVAEKGDEVNNLEIGDRVVIAFDLACGQCSFCKRHEYAACDTTNDSKLMDVNYGSHHSAIFGYTKLLGDVPGCQAEYIRVPFAEINCCKLPDDIPDSEGLFMSDVLCTSLHACTLGEVKKGDTVAIWGMGPIGLYAGRWAQILGASKVIGIEVVPERIELARQKFGFTVIDRNEVSDVPKKIMELVSNGVDCAIEASGFRFSTSILHKVERAVGLETDSPDMITECLNAVRKYGHVSIIADYVGTSNQFPIGHVVMKHLTIRSGQCPCQNYFGYVIDNIRSGKIDPRWMVTNKIKFDDLPDAYNKLFYKEDGYVKVYCDMTE
What are the official names of this protein?
Zinc-type alcohol dehydrogenase-like protein C1198.01.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
Protein: CYBH_ECO57
Sequence: MQQKSDNVVSHYVFEAPVRIWHWLTVLCMAVLMVTGYFIGKPLPSVSGEATYLFYMGYIRLIHFSAGMVFTVVLLMRIYWAFVGNRYSRELFIVPVWRKSWWQGVWYEIRWYLFLAKRPSADIGHNPIAQAAMFGYFLMSVFMIITGFALYSEHSQYAIFAPFRYVVEFFYWTGGNSMDIHSWHRLGMWLIGAFVIGHVYMALREDIMSDDTVISTMVNGYRSHKFGKISNKERS
What is the function of this protein?
Probable b-type cytochrome.
What are the official names of this protein?
Probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit.
What is the protein family that this protein belongs to?
Belongs to the HupC/HyaC/HydC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS4_MYCTU
Sequence: MARYTGPVTRKSRRLRTDLVGGDQAFEKRPYPPGQHGRARIKESEYLLQLQEKQKARFTYGVMEKQFRRYYEEAVRQPGKTGEELLKILESRLDNVIYRAGLARTRRMARQLVSHGHFNVNGVHVNVPSYRVSQYDIVDVRDKSLNTVPFQIARETAGERPIPSWLQVVGERQRVLIHQLPERAQIDVPLTEQLIVEYYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: AMPA_RICCN
Sequence: MLNVNFVNEESSTNQGLVVFIDEQLKLDSNLIGLDQQHHGLISKTIQNKLQFTGKYGQIKVIPSVIKSGEVRYLIIAGLGNEEKLTEAKIEELGGKILQHATGCKISTIGLKLTNRISRFTSQTFASLVASGAFLASYRFDKYRTTLKEAEKFAVESIEIFTDNSTETAKLFEIKKLIAEAVFFTRDISNEPSNIKTPQVYAERIVDRLEPLGVDVDVIGEREMKNLGMGALLGVGQGSQNESKLVVMEYKGGSKDAPTIALVGKGVIFDTGGISLKPSSDMHLMRYDMGGSAAVVGTIIAVAGQKLPINIVGVVGLVENMPSGNAQRPGDVVTTMSGQTAEVLNTDAEGRLVLADAVWYAQEKFKPKCVIDVATLTGAITIALGNTYAGCFSNNDELADKLIKVGEEVNEKLWRMPLHDEYDAMINSDIADMANIGNVPRAAGSCIAAHFIKRFIKDGVDWAHLDIAGVANSNKASALGPKGAVGYGVRLLEKFIKEYT
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_STRPI
Sequence: MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVYGAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLRWLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL16_EHRRW
Sequence: MFIPKKTKYKKDFKGRISGNAKGGYTLAFGTYGLKSLEPGRLTSKQVESARRSISRTLKRVGKVWIRVFCHTPVSKKPMDVRMGKGKGSIEMWVCKVKPGKILFEISGVSLNLAKEALQKSQAKLPVKCKFISDEL
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ILVC_BUCMH
Sequence: MKNYFNSLNFRQKLINLQKCKLIDNQFLSEKNNVLKGKNIVIVGCGSQGLNQGLNMRDSGLNISYALRDDSIFNKNQSWINATSNGFFVGTYENIIPTADLVINLTPDKQHEQVVNVLQKFMKPNSVLGFSHGFNIVEVGQLIRNDITVIMVAPKCPGTEVREEYKRGFGVPALIAVHSENDPHDIGFEIAKSWAISIGSHHAGILHSSFIAEVKSDLMGEQTILCGMLQASSLVCYNQLIFQGVNPSYAGKLIQTGWEVITESVKHGGITLMLDRLSNTAKIRAYFLSKKLKKIFFPLFRKHMDDIISGEFSKNMMFDWKNNDQQLKEWRTEIQNTDFEKCNIYYKQIPEQEYFDNGLLMVAILKAGIELSFEIMIETGIKEESAYYESLHELPLIANTIARKRLYEMNLVISDTAEYGSYLFSHAAIPLLKKFMNELQPGDLGNKISTSELDNITLYKVNAKIESHPIEIIGKKLRLYMTSMVPIKTK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: YP119_YEAST
Sequence: MHPLVDELTLSRYLTHGTSVLSSSLYSVAFFLFFFPNFLFFCSCPNHKWVSLPFIGMDILEALCFYREGKIRNIFEIGGLLLQSFYN
What are the official names of this protein?
Uncharacterized protein YPL119C-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: APOA4_ACIJB
Sequence: MFLRAVVLTLALVAVTGARAEVSPDQVATVVWDYFSQLSNNAKEAVEHLQQSELTQQLNALFQDKLGQVNTYADNLQKKLVPFATELHERLTKDSEKLKEEIRKELEELRARLLPHANEVSQKIGDNVRELQQRLGPYADELRTQVNTHAEHLRRHLTSHAQRMEAVLRENVDNLQSSLTPYADEFKAKIDRNIEELKGHLTPYADELKVKIDQNVEELRRSLAPYAQDVQEKLNHQLEGLAFQMKKNAEELKAKITANADELRQRLAPVVEDVRGKLRDNAKGLQESLAQLNSHLDRQVEEFRHNMGPYGDTFNRALVQQVEELRQKLGSYAGGMEDHLSFLEKDLRDKVNSFFSTLKEKENQDMPLALPEQEQAPGPLES
What is the function of this protein?
May have a role in chylomicrons and VLDL secretion and catabolism (By similarity).  Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT (By similarity).  Apoa-IV is a major component of HDL and chylomicrons (By similarity).
What are the official names of this protein?
Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL35_BRASO
Sequence: MPKLKTKSGAKKRFKVTGTGKVMHAQRGKRHGMIKRTKKQIRQLRGTRVLFKTDGDNVKKYFLPNA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: OBG_BREBN
Sequence: MFVDQVKVYVKGGDGGNGAVSFRREKYVPLGGPAGGDGGQGGDVVFVVDEGLRTLVDFRYQRHFKAPRGEHGRNKSQHGAGAEDMVVRVPPGTTVIDDDTKEVIADLVEQGQRAVIAKGGRGGRGNNRFANSSNPAPHISENGEPGQERYIVMELKLIADVGLVGYPSVGKSTLLSSVTAAKPKIAAYHFTTLTPNLGVVDLGERSFVMADLPGLIEGAHEGVGLGHQFLRHVERTRLIVHVIDMAAVDGRDPYEDYLQINRELTLYNLKLEDRPQIVVANKMELPEAEENLRIFKEKAPDVKVYEISAATSKGVQELMYAIGDTLATIPDKPAVEEVAEVEERVVFRAEKEPDAFEITRDNEVFVVSGEKIEKLVRMTNLNSYDAAQRFARQMRSMGVDDALRKLGAKDGDTVRIGKLEFDFVE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPNP_SULNB
Sequence: MKQFENVNVELEGNSYFDGAVTSRTVNFPDGSRKTLGFMLPGEYEFGTAAAELMEITSGELDVKLPGSDEWLSIKGGESFNVPADSKFQVKVKRVTDYCCSYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: NDUA1_GORGO
Sequence: MWFEILPGLSVMGVCLLIPGLATAYIHRFTNGGKEKRVAHFGYHWNLMERDRRISGVDRYYVSKGLENID
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1, Complex I-MWFE, CI-MWFE, NADH-ubiquinone oxidoreductase MWFE subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA1 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: UREF_AZOC5
Sequence: MTMAETGAPPSALALFAWLSPGFPVGAYAYSHALEWAAEAGDITDESSLESWLRDLMLLGFGRADGILLAHAYGAGAAGDVPALAQVNARAVALSPTAELRLETCQQGRSFLDAVRAAWPHGGLDAAAAHLPPDVAYPVAVGYAAALHGVPRAAVLEAYLFAVTQTLVSAALRIAPIGQTAGTRVVARLMPAVQALAGDIPTLTLDDLGTATFRADLGSMRHETQYTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_SALAR
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLNDDSLVRQLYGAPTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEHQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: SLYX_PSESM
Sequence: MNLEERVMELESRMAFQDDTIQALNDVLVKQRREFDHLQQQMAAMIKRQEEMGSQFDTFEEDAPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.