PharMolix/UniProtQA huggingface dataset:
Protein: CDC16_CAEEL
Sequence: MSAISPDTKSFAIPTLADEGSSSKPASSLDLPKHESIRFKPIKTLASRIDGSEYYDEASMEKVMEMLEIGRTDEAVAYADTLYSNIIDDEQQDIVTIAEYVKILVVLRQWRRISHIIARGNYHQIHIVFAYYAATALFQRKLYEDVAELSVGHLLPSNGQIGPLPVRTLSQVTGRYVEEERMKYSFANMAELDNSSKKLRMVPALMITIAESFLKLMNRDAAMICINYALSLDNTTLHVERLMAKYNLVEPAMWEKYRKVRNEQLKLHEGNHDPRILMERAQRAYEMGRFRETKKITDELFDLFGPHPECIILRIHCLTMLKDSRSLLELGHQLVSDDPHIPLPWYCVAMYYYSIGANSRARNFISKCTMMDSTFAEGWVAFGHILHYEVEHEQSMSCYYRASKLVDKSSEPFLYTSLQYSTHSQKLSKKFMGEAVARAPNDPLIRHEEACVAYTAKSYAEADILFRTVLYMVTETDEIIPIEEVLKKKIDDFWHPMLNNIGHIARRQGRLNEAIMFYQKAIRMEPKFVDAIASTALCYAVLGNIDKATEFFNKALAIDPFNETIRQCLSKMIQASKESYSVDQQTLPPAYNSETYFGAQEILPYCAIRKPRNDGFVVPSIVSSSQPFMSMLRDRLRRQDQLYAQEPDNDAGNQV
What is the function of this protein?
Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (By similarity).  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (By similarity).  Developmental role in early embryogenesis and the metaphase to anaphase transition in oocyte and spermatocyte meiosis and mitosis in germ cells (PubMed:11134076).  Required for embryonic anterior-posterior axis formation (PubMed:11832245).  Plays a role in regulating the abundance of glr-1 receptors in postmitotic neurons, which may in turn control animal locomotion (PubMed:15556870).  Involved in regulating GABA neurotransmitter release at neuromuscular junctions in GABA motor neurons (PubMed:24321454).
What are the official names of this protein?
Cell division cycle protein 16 homolog, Abnormal embryogenesis protein 27, Anaphase-promoting complex subunit 6, APC6.
What is the protein family that this protein belongs to?
Belongs to the APC6/CDC16 family.
What are the subcellular locations of this protein?
Cell junction. Synapse.
Protein: RL11_PSEPF
Sequence: MAKKITAYIKLQVKAAQANPSPPVGPALGQHGVNIMEFCKAFNARTQGLEAGLPTPVIITVYSDRSFTFETKSTPASVLLKKAAGLTSGSARPNTVKVGTVTRAQLEEIAKTKNADLTAADMDAAVRTIAGSARSMGLNVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: EI24_HUMAN
Sequence: MADSVKTFLQDLARGIKDSIWGICTISKLDARIQQKREEQRRRRASSVLAQRRAQSIERKQESEPRIVSRIFQCCAWNGGVFWFSLLLFYRVFIPVLQSVTARIIGDPSLHGDVWSWLEFFLTSIFSALWVLPLFVLSKVVNAIWFQDIADLAFEVSGRKPHPFPSVSKIIADMLFNLLLQALFLIQGMFVSLFPIHLVGQLVSLLHMSLLYSLYCFEYRWFNKGIEMHQRLSNIERNWPYYFGFGLPLAFLTAMQSSYIISGCLFSILFPLFIISANEAKTPGKAYLFQLRLFSLVVFLSNRLFHKTVYLQSALSSSTSAEKFPSPHPSPAKLKATAGH
What is the function of this protein?
Acts as a negative growth regulator via p53-mediated apoptosis pathway.  Regulates formation of degradative autolysosomes during autophagy (By similarity).
What are the official names of this protein?
Etoposide-induced protein 2.4 homolog, p53-induced gene 8 protein.
What is the protein family that this protein belongs to?
Belongs to the EI24 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Cytoplasm. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: 14KL_BRUC2
Sequence: MNSFRKTCAGALALIFGATSIVPTVAAPMNMDRPAINQNVIQARAHYRPQNYNRGHRPGYWHGHRGYRHYRHGYRRHNDGWWYPLAAFGAGAIIGGAISQPRPVYRAPAGSPHVQWCYSRYKSYRASDNTFQPYNGPRKQCRSPYSR
What is the function of this protein?
Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose.  Essential for virulence.  May be involved in LPS biosynthesis or polysaccharide transport (By similarity).
What are the official names of this protein?
Lectin-like protein BA14k.
What is the protein family that this protein belongs to?
Belongs to the BA14k family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ADF5_ORYSJ
Sequence: MAMAYKMATEGMNVKEECQRWFMEMKWKKVHRFVVYKIDERSRAVLVDKVGGPGEGYEELVAALPTDDCRYAVFDFDFVTVDNCQKSKIFFIAWSPTASRIRAKILYATSKQGLRRVLDGVHYEVQATDSSEMGYDVIRGRAQ
What is the function of this protein?
Actin-depolymerizing protein.  Severs actin filaments (F-actin) and binds to actin monomers (By similarity).
What are the official names of this protein?
Actin-depolymerizing factor 5, ADF-5, OsADF5.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
Protein: UNG_MYCGE
Sequence: MVMDDLFQRMVSCVLPSWRAFIDEEVKKPYFQALLEKLKALKATIIPKPELIFRVFSFFKPIDTKVIIFGQDPYPSPNDACGLAFASNNSKTPASLKRIILRLEKEYPSLKQESSWQQNFLLNWAEQGVLLLNGILTTTVFIRNAHKNWGWEEFNCNLLTFLKNQNIKPLLVFLGVQTKNFVVKSIGNVDGFEHLSYPHPSPLSGNLFLTNPNDLFKTINNWLKQHNQKIINWAVVKNASFDQLS
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_STAEQ
Sequence: MQYDHLLVRYGELTLKGTNRKMFVNQLKDNVKRALIPLSGYHVKGKRDRMYIELSPEADINEIIQRLSKVYGIKSISPVIKIDKNEEKINQSAIQLSHDFEKGSTFKVDVKRVDKSFRLDTYELQRQVGGAILKENNNITVNVKNPDYEIKIEVRMDAIYIYEKVIAGAGGLPVGTGGKTLLMLSGGIDSPVAGIEVMKRGVTVEAIHFHSPPFTSEKAKDKVIELTRILAERVGPIKLHLVPFTEIQKQINKVVHPRYTMTSTRRMMMRISDKVVHQINANAIVNGENLGQVASQTLKSMYAINHVTATPVLRPLLTLDKEDIIKKAKELGTFETSIQPYEDCCTIFTPKNPVTEPDFDKVIKYESVFNFDEMIENAVENIETLTIDQNYKSAKEQSTDSLIKDLF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLAS_GINBI
Sequence: VEVLMGGSGGELAFIPNELQVNAGEQIVFKNNAGFPHNVIFDEDAVPAGVDVSSISMSEEDLLNAPGETYVVKLDKKGTYRFFCAPHQGIGMSGIVTVN
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
What are the official names of this protein?
Plastocyanin.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
Protein: LRGA_STAEQ
Sequence: MVILEQTHLVKNKTVDNKKSMKYSIFQQALTIAVILLISKIIESFMPIPMPASVIGLVLLFIALCTGIVKLGQVETVGTALTNNIGFLFVPAGISVINSLPILKQSPILIILLIIISTLLLLICTGFASQLLVTKSLFPSKEKNEETSHVGG
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB.  The LrgAB and CidAB proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. LrgA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATG5_PHANO
Sequence: MSSREVTSRLREKVWNGSVPLEIRLHKGDCRTYDDSDAYLIQFPRLSYLALLIHKLHAFFAPSLIYPDIHPSDLWFSYEGVPLKWHYPLGLLYDLYSGAEPYHPSDSPPPSPTTPSKQDSKQPLPWRLTLHTSAYPTTQLIPLDNNNLQIHDLFIHSVKEADYLRTGTGKTVMFLSQADSTQLWDAVVKHDFALFNPINQKLLNPQGVNLRHLPVRLYLPHAGVDEEDRGMGSVRVVQSLVKVEVGSRQPQTIGTALNQILPTLFPSRRSALLAQAVLHGAVVPLGASVEELIRSVAYLDGWLHIAIVMMG
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy).  Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production.  Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: HEMA_I77A8
Sequence: MKTIIALSYIFCQVLAQNLPGNDNSTATLCLAHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGRICDSPHRILDGKNCTLIDALLGDPHCDGFQNEKWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFINEGFNWTGVTQNGGSYACKRGPDNSFFSRLNWLYKSESTYPVLNVTMPNNDNFDKLYIWGVHHPSTDKEQTKLYVQASGRVTVSTKRSQQTIIPNVGSRPWVRGLSSRISIYWTIVKPGDILLINSNGNLIAPRGYFKIRTGKSSIMRSDAPIGTCSSECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGIFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIGSIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQKGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RL5_AERHH
Sequence: MAKLHDYYKSDVVNELSKQFGYKTIMQVPRIEKITLNMGVGEAISDKKLLENAAADMAAISGQKPLITKARKSVAGFKIREGYPIGCKVTLRGERMWEFLERLICISVPRIRDFRGLNAKAFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTSANTDEEGRALLAAFNFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: LUXS_GEOTN
Sequence: MPSPVESFELDHCAVKAPYVRHCGVHKIGSDGVVNKFDIRFCQPNKEAMDPAAIHTLEHLLAYTLRKHVTKYDHFDIIDISPMGCQTGFYLVVSGSPTVDEIIDLLEETMKDALNATEVPAATERQCGQAKLHDLEAAKELMRFWLSQEKSELKKVFG
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: ACRT_ASPA1
Sequence: MADHGEHGVPEQQNAPPKKGLRFWLIFLAIGIATFVAALDTSIISTALPTITADLGSEELYIWIINTYLLSSTVSSAIVGQLSNIFGRRSMTTLALLIFAVGSAISGAARDTGMLLAGRTIQGLGGGSITTLSEVLVCDMVSLRERGVYAGILGAAWTLAAVVGPIMGGGFTQNVSWRWIFYINLPIAGSSLFLIVTLLRVRNPRSDTSILRRLRTIDWGGITLLTLGVTAILLSLTWAGTTHPWSSWRTIVPLILGFLGLLGFIAYEALPPEPTMPLRLFRNRTAATLFVMAFIYSLLLFWVCYFLPIYFQAVLNATPTRSAVMLFPVATTTAPAGIVAGILMTKTGRYRSFQYIGFALMTIACGLFTLLDQSTTTGEWTGYQILFGVGTGIVFTTGLPPILASLPESDVATGTATWIFMRNFGAIWGTAIPAAVFNTKANALASQTIDDPTVRGLLVNGGAYERATKAFVSSFKSRPAVMRAIRRLYVVSLREVWQVSIAFCGVGFLLCFLVKAYRLREELNTEYGMQLWRPVFKRLVCTWYLAGSANLMCT
What is the function of this protein?
MFS-type transporter that may have a role in the biosynthesis of acurin A, a highly reduced polyketide coupled to a serine via a peptide bond; either in extra- or intracellular transport.
What are the official names of this protein?
Acurin A biosynthesis cluster MFS-type transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RP07_VACCW
Sequence: MVFQLVCSTCGKDISHERYKLIIRKKSLKDVLVSVKNECCRLKLSTQIEPQRNLTVQPLLDIN
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118/D6 and OPG134/A8, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
What are the official names of this protein?
DNA-directed RNA polymerase 7 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 7 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle.
Protein: CP143_MYCTO
Sequence: MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS
What are the official names of this protein?
Putative cytochrome P450 143.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: ANXA8_PANTR
Sequence: MAWWKAWIEQEGVTVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKSLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAHDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSGDYKNALLSLVGSDP
What is the function of this protein?
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
What are the official names of this protein?
Annexin A8, Annexin-8.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
Protein: RIMP_STAA9
Sequence: MSKITEQVEVIVQPIMEDLNFELVDVEYVKEGRDHFLRISIDKEGGVDLNDCTLASEKISEAMDANDPIPEMYYLDVASPGAERPIKKEQDFQNAITKPVFVSLYVPIEGEKEWLGILQEVNNETIVVQVKIKARTKDIEIPRDKIAKARHAVMI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_ENTH1
Sequence: MSARKFVVGGNWKCNGTLASIETLTKGVAASVDAELAKKVEVIVGVPFIYIPKVQQILAGEANGANILVSAENAWTKSGAYTGEVHVGMLVDCQVPYVILGHSERRQIFHESNEQVAEKVKVAIDAGLKVIACIGETEAQRIANQTEEVVAAQLKAINNAISKEAWKNIILAYEPVWAIGTGKTATPDQAQEVHQYIRKWMTENISKEVAEATRIQYGGSVNPANCNELAKKADIDGFLVGGASLDAAKFKTIINSVSEKF
What is the function of this protein?
Catalyzes the interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic and gluconeogenic pathways.
What are the official names of this protein?
Triosephosphate isomerase, EhTIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
Protein: CGHB_SAIBB
Sequence: MEMLQGLLLCLLLSTGGAWASKEPLRPPCRPTNVILAVEKEGCPVCVPFNTTICAGYCSSMVRVMQTLPPLPQTVCNYHELRFTSVRLPGCRRGVDPVVYMPMAVSCRCALCRRSYSDCGSFRNESLGCDYATSQDSSSNVPPSNLTSPSQLLEPAVTPLVPQ
What is the function of this protein?
Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
What are the official names of this protein?
Choriogonadotropin subunit beta, CG-beta, Chorionic gonadotrophin chain beta.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCPR2_ASPFU
Sequence: MSKPGDYDAVRKDIIAQLKKPGYDDGSAGPVFVRLAWHSAGTYDLETDTGGSNGAGMRYEAEGGDPANAGLQHGRAFLEPVKEKHPWITYADLWTLAGVVAIEALGGPKVVWKPGRTDLVDDSKVPPRGRLPDATQGAEHLRAVFYRMGFNDQEIVALAGGHTLGRCHIDRSGFQGPWVNNPTRFSNQFFKLLLTLDWKPKTLPNGISQFVYVDPDAEEGDEPLMMLPTDIALKTDPAFRVWVDKYAADKDLFFDHFAKAFAKLMELGIKRDENDRVINADNVKGGYISAPKKSNHPTGPAKGAQGGCPVAASQGGCPRAKL
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Putative heme-binding peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
Protein: RT12_PANGI
Sequence: MPTLNQLIRHGREEKRRTDRTRASDQCPQKQGVRPRVPTRTPKKPNSAPRKIAKVRLANRHDIFPHIPGEGHNSQEHSMVLIRGGRVKDSPGVKSHCIRGVKDLLGIPDRRRGRSKYGAEKPKSI
What is the function of this protein?
Protein S12 is involved in the translation initiation step.
What are the official names of this protein?
Ribosomal protein S12, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CTF18_YEAST
Sequence: MVDTAPYIGSLGRSSLFDTGDIEQAPGNNAIGINEEDIHAFVSSTGETVQLKKKPAKLATGNISLYTNPDTVWRSDDTYGININYLLDKIEASGDDRTNAQKTSPITGKIGSDTLWVEKWRPKKFLDLVGNEKTNRRMLGWLRQWTPAVFKEQLPKLPTEKEVSDMELDPLKRPPKKILLLHGPPGIGKTSVAHVIAKQSGFSVSEINASDERAGPMVKEKIYNLLFNHTFDTNPVCLVADEIDGSIESGFIRILVDIMQSDIKATNKLLYGQPDKKDKKRKKKRSKLLTRPIICICNNLYAPSLEKLKPFCEIIAVKRPSDTTLLERLNLICHKENMNIPIKAINDLIDLAQGDVRNCINNLQFLASNVDSRDSSASDKPACAKNTWASSNKDSPISWFKIVNQLFRKDPHRDIKEQFYELLNQVELNGNSDRILQGCFNIFPYVKYSDNGIRKPANISDWLFFHDLMYQSMYAHNGELLRYSALVPLVFFQTFGDIANKDDIRMKNSEYEQRELKRANSDIVSLIMRHISVQSPLMASFTDRKSLIFEILPYLDSMISSDFNKIRNLKLKQAIMEELVQLLKSFQLNLIQNRSEGFDVRGGLTIDPPIDEVVLLNPKHINEVQHKRANNLSSLLAKIEENRAKKRHIDQVTEDRLQSQEMHSKKVKTGLNSSSSTIDFFKNQYGLLKQTQELEETQKTIGSDETNQADDCNQTVKIWVKYNEGFSNAVRKNVTWNNLWE
What is the function of this protein?
Essential for the fidelity of chromosome transmission.  Required for the DNA replication block checkpoint.  Component of the RFC-like complex CTF18-RFC which is required for efficient establishment of chromosome cohesion during S-phase and may load or unload POL30/PCNA.  During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC.  The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit.  Dissociation of RFC from the clamp leaves the clamp encircling DNA.
What are the official names of this protein?
Chromosome transmission fidelity protein 18.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. CTF18 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: BTUD_SALEP
Sequence: MSQLMQLKDVAESTRLGPLSGEVSAGEILHLVGPNGAGKSTLLARMAGLTSGEGSIRFGGAPLEAWATATLAQHRAYLAQQQNPPFAMPVWHYLTLHQPDKTRTGQLNEVADMLGLGDKLGRSVNQLSGGEWQRVRLAAVVLQIHPDANPVGQLLLLDEPMNSLDVAQQNALDRVLHHLCQAGIAIVMSSHDLNHTLRHAHKAWLLKRGKLIACGRREEVLTPSYLAQAYGLRFRRLDVEGHPTLISAT
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TUSC_ECOSE
Sequence: MKRIAFVFSTAPHGTAAGREGLDALLATSALTDDLAVFFIADGVFQLLSGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLEADALRRELANYDVILRF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6M_CEPGR
Sequence: MTYFVVFLGLCFVLGGLAVASNPSPYYGVVGLVLASVAGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPEAWGDWGVVGYGMSFIVVLVVGVVVGGFVEGWDFGVVTVDSAGVFFARLDFSGVAMFYSCGVGMFLVAGWGLLLTLFVVLELVRGLSRGAIRAV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RS3_BACLD
Sequence: MGQKVNPVGLRIGVIRDWESKWYAGKDYADFLHEDLKIREFINQRLSDASVSKVEIERAANRVNITIHTAKPGMVIGKGGSEVEALRKALNSLTGKRVHINILEIKRADLDAQLVADNIARQLENRISFRRAQKQQIQRTMRAGAQGIKTMVSGRLGGADIARSEYYSEGTVPLHTLRADIDYATSEADTTYGKLGVKVWIYRGEVLPTKKKTEEGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.