PharMolix/UniProtQA huggingface dataset:
Protein: CP24A_MOUSE
Sequence: MSCPIDKRRPLIAFLRRLRDLGQPPRSVTSKAHVKRAPKEVPLCPLMTDGETRNVTSLPGPTNWPLLGSLLEIFWKGGLKKQHDTLAEYHKKYGQIFRMKLGSFDSVHLGSPSLLEALYRTESAHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLDKKINEVLADFMGQIDELRDERGRIQDLYSELNKWSFESICLVLYEKRFGLLQKDTEEEALTFIAAIKTMMSTFGKMMVTPVELHKRLNTKVWQAHTLAWDTIFKSVKPCIDHRLERYSQQPGADFLCDIYQQDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQRLLREIQSVLPDNQTPRAEDVRNMPYLKACLKESMRLTPSVPFTTRTLDKPTVLGEYTLPKGTVLTLNTQVLGSSEDNFEDADKFRPERWLEKEKKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIIQKYNIVATDSEPVEMLHLGILVPSRELPIAFCPR
What is the function of this protein?
A cytochrome P450 monooxygenase with a key role in vitamin D catabolism and calcium homeostasis.  Via C24-oxidation pathway, catalyzes the inactivation of both the vitamin D precursor calcidiol (25-hydroxyvitamin D(3)) and the active hormone calcitriol (1-alpha,25-dihydroxyvitamin D(3)).  With initial hydroxylation at C-24 (via C24-oxidation pathway), performs a sequential 6-step oxidation of calcitriol leading to the formation of the biliary metabolite calcitroic acid.  Hydroxylates at C-24 or C-25 other vitamin D active metabolites, such as CYP11A1-derived secosteroids 20S-hydroxycholecalciferol and 20S,23-dihydroxycholecalciferol.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via FDXR/adrenodoxin reductase and FDX1/adrenodoxin.
What are the official names of this protein?
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 24-OHase, Vitamin D(3) 24-hydroxylase, Cytochrome P450 24A1, Cytochrome P450-CC24.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: T255A_XENLA
Sequence: MLTQQPSQRTDIQAADSTGSFNKRRRNSVFVTVTLLIVSSLIFTLGMAATTRTENVTVGGYYPGVILGFGSILGIIGSNLIENKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHLDLRPLYAGKCRYHSTTHNDHTTEVTCQQPMRNPCVLKIRSNTCYCCDLYNCGRIGNSGLYYEYTDVKSCQDVVHLYHLLWSVTILNIVGLFLGIITAAVLGGFKDMNPALPAISCIAETPRPTVQYNTRPAVPSYNTYYHSTPHLPPYTAYDLQHSSVFPASTPSGLSDDPNGQASSFMWPSNAPPRYSPPYFPPDEKPPPYTP
What are the official names of this protein?
Transmembrane protein 255A, Protein FAM70A.
What is the protein family that this protein belongs to?
Belongs to the TMEM255 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LAMB_AERHY
Sequence: MKMKAKWLPIAAAVTAALASQAAFAVDFHGYFRSGVGVSSDGDMQTLSKQKVGRLGNEDDTYGEVQLGQEVFNKDGKTFYVDSMFAMIPNGSNDWEGTGSVCNFDEKQCSGDSEFALRQFNVQAKGLLGFAPEATLWAGKRYYQRHDIHISDFYYWNISGAGAGIEGVQAGPGKISFAWVRNDRGWDGKDGWTKFEGMDVNTLDLRYAGIPLWQDASLEVGVDYAIANPTDAQKDSSNVQYKNAKDGVMLTAELTQGIFGGFNKTVLQYGTEGYSKTMAFYGDGSWYGAEAKDGADGFRIINHGVIPMGNSWEMGHQLVYGVGNDMWDGNDKWETMSVVARPMYKWDDFNKTIFEGGYFKDKNKSTNGSSLEDSGYKLTLSQTWSAGSSFWARPEIRVFTSYAALDDNDMAGTPYNSKTSKDTWNFGVQAEAWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin, Maltose-inducible porin.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: SYR_CITBB
Sequence: MKEQLRACILKGIEGCFADGTLTSGEVPAINVEKPAHAEHGDFATNVAMQMAKQQRKAPRAVAEILVAKLAGASDLIESLEIAGPGFINFFIKDSAWRRTLTEIDRAGDAWGKSGIGRGKKVQVEFVSANPTGPLHIGHGRGAATGDAVASLLSAAGFDVQREYYINDAGNQMNTLGLSGLLRYKELLGEKIDFPETCYQGDYMKDIARDAVTKYGDRFLKVSQEDGVAFFSKMGGDLILAGIDQDLQDFGIRFDHWFSEQSLFDEGKVKSAIEEMQAKGLIYEQEGALWFRTTDYGDDKDRVVVRSNGVTTYFASDIAYHRDKFARGFDWVIDVWGADHHGYVPRLKSVVQGLGRDASDLGIILVQLVSLLRDGVPVAMSTRSGEFVTLKEVVDEVGRDAARFFFLMRRSDSQLDFDLELAKRQSNDNPVYYVQYAHARIKSIFDTARERGVEPRFDSVKLELLQTPEDLSLVKKLSVYPEILEGGAVNFEPHRITYYLQELAGEFHSFYNKSRVITPEEPELTQARLFLLHCVAITLKNALTVLGISAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SA2C_NAJSP
Sequence: MKTLLLTLVLVTIVCLDLGYTLKCNKLVPLFYKTCPAGKNLCYKMYMVATPKVPVKRGCIDVYPKSSLLVKYVCCNTDRCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 2c, Cardiotoxin-2c, CTX-2c, Ctx2c.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: TAGL_BOVIN
Sequence: MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIVMQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVTKTDMFQTVDLFEGKDLAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS
What is the function of this protein?
Actin cross-linking/gelling protein.
What are the official names of this protein?
Transgelin, 25 kDa F-actin-binding protein, Smooth muscle protein 22-alpha, SM22-alpha.
What is the protein family that this protein belongs to?
Belongs to the calponin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAH1_CHLRE
Sequence: MARTGALLLVALALAGCAQACIYKFGTSPDSKATVSGDHWDHGLNGENWEGKDGAGNAWVCKTGRKQSPINVPQYQVLDGKGSKIANGLQTQWSYPDLMSNGTSVQVINNGHTIQVQWTYNYAGHATIAIPAMHNQTNRIVDVLEMRPNDAADRVTAVPTQFHFHSTSEHLLAGKIYPLELHIVHQVTEKLEACKGGCFSVTGILFQLDNGPDNELLEPIFANMPSREGTFSNLPAGTTIKLGELLPSDRDYVTYEGSLTTPPCSEGLLWHVMTQPQRISFGQWNRYRLAVGLKECNSTETAADAGHHHHHRRLLHNHAHLEEVPAATSEPKHYFRRVMLAESANPDAYTCKAVAFGQNFRNPQYANGRTIKLARYH
What is the function of this protein?
Reversible hydration of carbon dioxide.
What are the official names of this protein?
Carbonic anhydrase 1, Carbonate dehydratase 1, CA1.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GCS2_ECO45
Sequence: MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNQITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLLYKFNRFQACRYGLEGVITDPHTGDRRSLTEATLRLLEKIAPSAHKIGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGE
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: ALR_SHEPC
Sequence: MKPFPRAEISSSALQNNLAVLRQQASASQVMAVVKANGYGHGLLNVANCLVNADGFGLARLEEALELRAGGVKARLLLLEGFFRSTDLPLLVAHDIDTVVHHESQIEMLEQVKLTKPVTVWLKVDSGMHRLGVTPEQFATVYARLMACPNIAKPIHLMTHFACADEPDNHYTDVQMAAFNELTAGLPGFRTLANSAGALYWPKSQGDWIRPGIALYGVSPVAGDCGTNHGLIPAMNLVSRLIAVRDHKANQPVGYGCYWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGRVSMDMLTVDLGQDATDKVGDDVLLWGQDLPVEEVAERIGTIAYELVTKLTPRVAVCLA
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: FLIA_ECOLI
Sequence: MNSLYTAEGVMDKHSLWQRYVPLVRHEALRLQVRLPASVELDDLLQAGGIGLLNAVERYDALQGTAFTTYAVQRIRGAMLDELRSRDWVPRSVRRNAREVAQAIGQLEQELGRNATETEVAERLGIDIADYRQMLLDTNNSQLFSYDEWREEHGDSIELVTDDHQRENPLQQLLDSNLRQRVMEAIETLPEREKLVLTLYYQEELNLKEIGAVLEVGESRVSQLHSQAIKRLRTKLGKL
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor controls the expression of flagella-related genes.
What are the official names of this protein?
RNA polymerase sigma factor FliA, RNA polymerase sigma factor for flagellar operon, Sigma F, Sigma-27, Sigma-28.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. FliA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_PARD8
Sequence: MSEVNEETLRAREALAGHYKEVLGLLGEDVEREGLLKTPERVAKAMQFLTKGYHEDPEAVLRSAMFQEEDYKQMVIVKDIDFFSLCEHHMLPFFGKAHVAYIPKKYITGLSKIPRVVDIFARRLQIQERMTMQIKDCIQRTLDPLGVMVVIEAQHMCMQMRGVEKQNSLTTTSDFTGFFQQAKTREEFMNLIKHNR
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: H4_PARLI
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYCEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RRP3_GUITH
Sequence: MPKFTLKVLWLDNNVAVAVDQIIGNGTSPLTCYFFWPRNDAWEQVKAELESKPWIEEKERIELLNKTTELINCWQEQSKKYSFKEIQSKFPDFIFAGAN
What is the function of this protein?
Probably a ribosomal protein or a ribosome-associated protein.
What are the official names of this protein?
Probable 30S ribosomal protein 3, chloroplastic, PSRP-3.
What is the protein family that this protein belongs to?
Belongs to the chloroplast-specific ribosomal protein cS23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NADK1_GEOKA
Sequence: MKRTDAPLVFAITSKGDDISNALAQKMKTYLLDFDLRYDEEEPDLVISVGGDGTLLYAFHRYCHRLDKTAFVGVHTGHLGFYADWVPEELEKLVIAIAKTPYQVVEYPLLEVTIRYLNGGSEAKYLALNECTVKCVSGTLVMDVEIRGDLFERFRGDGLCISTPTGSTAYNKALGGAILHPSLEAIQVTEMASINNRVFRTIGSPLVLPAHHTCLLKPVNHVDFQITIDHLSLLHKEVKSIQCRVADEKVRFARFRPFPFWRRVRDSFIAD
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 1, ATP-dependent NAD kinase 1.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYPH_SODGM
Sequence: MFLAQEIIRKKRDGEPLSDEEIRFFINGVYDNTVSEGQIAALAMTIFFHDMDLQERVALTLAMRDSGHTLDWRREALGGPVVDKHSTGGVGDVTSLMLGPMIAACGGFVPMVSGRGLGHTGGTLDKLEAIPGLAIFLDDDAFRSQVKQVGVAIMGQTHSLAPADKRIYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGALMPTLAGSEALAQAIVGVANGAGCRTIALLTDMNQVLASSAGNALEVREAVRFLTNDERNPRLFEVTMALCSEMLMIAGLAHSEDAARTALVRALDSGEAAERFGRMVAVQGGPADFVQRYDLYLPVATLSKPVFPAGEGYIRSMDTRALGMTVVALGGGRQRARDAIDYSVGLTEMARLGDYVDANTPLAVVHAASEESWARAAEAVRAAIQLGDVAPQALPVVYRRITAAAD
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: CE164_HUMAN
Sequence: MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPGEWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKDKKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
What is the function of this protein?
Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells.  Plays a critical role in G2/M checkpoint and nuclear divisions.  A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1.  Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1.
What are the official names of this protein?
Centrosomal protein of 164 kDa, Cep164.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus. Note=Localizes specifically to very distally located appendage structures on the mature centriole from which initiate PC formation (PubMed:26337392). Persisted at centrioles throughout mitosis. Expressed in chromatin-enriched nuclear fraction of HeLa cells. In response to DNA damage, it translocates to nuclear foci that contain the DNA damage response proteins KAT5/TIP60 and CHEK1.
Protein: RL9_PELUB
Sequence: MKVILLENLRRIGSIGEIIDVKRGFARNFLISNKKALYASKENIAEVEKIKSELSKKDTEKKKEAQKISEQINNKEYEIKKLSTENKELYGSVKPTEISKLILENDKLDIKPSMIQPITEIKSIGKFKVKIILHSEVDSEITINVVTADTIQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: YHAH_SCHPO
Sequence: MKCFLICGSKKEPISINGTPNVVKSKYFEGDVKVRLRDYETPDEEYFEQSNDTCSIMIRGRFLPTESTLTADDILFGNQFEKPLRDVLPMGSNLLMKGLQYVDPSIEFDLYCDQPWAFSPFFATMTKMQVSDALLPMEYFEDHSSRRSQMQQQVIRQESSIDPNKYILADFCNPFFNPSTLSISIPYTKMSFSIKNYYNGQPLRYFCKTRDGNVIFAVEFDL
What are the official names of this protein?
UPF0590 protein C409.17c.
What is the protein family that this protein belongs to?
Belongs to the UPF0590 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SCRB_VIBCL
Sequence: MLLDTQLELAGGINNVTRILAPQGQVVLALKHPPHAPHLPDDVSLQSVLGEWQLSVQRTAEVSDQQLATIGKAISERQKLETLPYQTALDCPYRPLWHISPPQGLLNDPNGFIYHQGEYHLFYQWHPFVCEHKDKYWVHLKSLDLVHWQWQSVALTPSDWFDSHGVFSGHAVSHQQDLWLFYTGNTRLGVDRQRQTMQCAARMNANGEFEKLGPVIRCLPEGVTEHIRDPKVIYTQGKWHMLLGAQTLAHQGRLAVYHSDDLLHWHFDKLYGDELGNYGYMWECPDWFELQGEAFFVFGPQGIASANPHHTIEHQNRIFRATQNAQGEIALLQGWPLDEGFDFYAPQTAQTTDGRRVLCGWMGLPDETQHPSCDQGWIHQLTALRELEWREGKIYQHPLRELDTLRSEPHTLLLSDTVTELKAKSFDVQVTLPWGCQLRLMQNAQYCVTLTLDAENRLLRLDRSATQIRQGDTIRELKLDSPTVELRILADQSSLEIFINQGEHVMTSRIFTPLDATGISLHGASVDAKLYYMAPASAPFNLEVNV
What is the function of this protein?
Enables the bacterium to metabolize sucrose as a sole carbon source.
What are the official names of this protein?
Probable sucrose-6-phosphate hydrolase, Sucrase, Invertase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22L_BOVIN
Sequence: MAPKKDKKPKKSTWKFNLDLTHAVEDGIFDSGNFEQFLREKVKVNGKTGNLGNVVHIERFKNKIIVVSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDESESED
What are the official names of this protein?
60S ribosomal protein L22-like 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL22 family.
Protein: MOAC_VIBVU
Sequence: MSQFTHINASGEANMVDVSAKAETVREARAEAFVHMAPETLQLIVSGQHHKGDVFATARIAGIQAAKKTWDLIPLCHPLLLSKVEVQLQAIEAENKVRIESVCKLAGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLEKTGGKSGHFKVEA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: CYC_WICAO
Sequence: PAPFKKGSEKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRQSGKAEGYSYTDANIKKAVEWSEQTMSDYLENPKKYIPGTKMAFGGLKKEKDRNDLVTYLANATK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: LUXS_NEIG2
Sequence: MPLLDSFKVDHTRMHAPAVRVAKTMTTPKGDTITVFDLRFCIPNKEILPEKGIHTLEHLFAGFMRDHLNGAGVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWLASMQDVLNVKDQSKIPELNEYQCGTYLMHSLAEAQQIAQNVLARKVAVNRNGDLALDESLLNA
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: TX814_LYCSI
Sequence: MKLIIFTGLVLFAIVSLIEAQAENEKPCLAQYQVCTHAPGNCCSNLVCDCYGRYKSGARIGRNCFCLQKGVIYKRED
What are the official names of this protein?
U8-lycotoxin-Ls1e, Toxin-like structure LSTX-H14.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 08 (U8-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: G6PI_STAA3
Sequence: MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_SYNAS
Sequence: MGRIIGIDLGTTNSCVAVMEGGDPVVIANQEGNRTTPSIVAFTESGERLVGQVAKRQAVTNSENTVYAVKRLIGRKYNSKEVQYDKSISPFKISEAPNGDAQIEVRGRAYSPAEISSMVLVKMKQTAEDYLGEKITDAVITVPAYFNDSQRQATKDAGKIAGLNVLRIINEPTAAALAYGLDKKKDEKIAVFDLGGGTFDISILELGEGVFEVKSTNGDTHLGGEDFDQRIIDYLVSEFKKDQGIDIRSDKMALQRLKEAAEKAKMELSSSMETDINLPFITADASGPKHMNIKLTRARMEALVEELIDRLEGPCRTALKDAGLSPKDIDEVILVGGMTRMPRVQQKVKEIFDREPHKGVNPDEVVAVGAAIQGGVLGGEVKDVLLLDVTPLSLGIETLGGVMTKLIEKNTTIPTRKSQIFSTAADNQPAVSIHVLQGERSMAGDNRTLGRFDLVGIPPAPRGIPQIEVTFDIDANGIVHVSAKDLGTGKEQSIKITASSGLSETEIEKLVREAESHGEEDRKKKELVEARNSADAMAYGVEKNIKEFGDKVDAAEKARIEDAIAKVRKAVEGDDINAIRSAQDELTTASHKLAEAMYAKTSQAGAGPQPGAGPGTGGQGPGKKDEDVVDADFEEVK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: FTSZ_AZOVI
Sequence: MFELVDNVPQSAVIKVIGVGGGGGNAVNHMAATSIEGIEFICANTDAQALKNITARTVLQLGSGVTKGLGAGANPEVGREAAMEDRERIAEVLQGTDMVFITTGMGGGTGTGAAPVIAEVAKGLGILTVAVVTRPFPFEGRKRMQVAEEGIRLLAEHVDSLITIPNEKLLTILGKDASLLSAFAKADDVLAGAVRGISDIIKLSGMINVDFADVKTVMSEMGMAMMGTGFASGPNRAREATEAAIRNPLLEDVHLQGARGILVNITAGPDLSLGEYSDVGNIIEQFASDQAMVKVGTVIDPDMRDELHVTVVATGLGTRADKPMKVVDNTLQPAGAAAAAPAVPRGDQTVNYKDYERPTVQRQSHAASATAAKINPQDDLDYLDIPAFLRRQAD
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: MED31_MOUSE
Sequence: MAAAVAMETDDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFKDKAFVNYLKYLLYWKEPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRVRLQQALAEQQQQNNTAGK
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 31, Mediator complex subunit 31, Mediator complex subunit SOH1.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 31 family.
What are the subcellular locations of this protein?
Nucleus.