PharMolix/UniProtQA huggingface dataset:
Protein: ATPD1_VIBA3
Sequence: MSDLTTIARPYAKAAFDFAVDKGELDQWGQMLTFAAEVAQNDDVHNLLSGSMTAEKLAEVFIVICGEQFDEFGQNLIKVMAENGRLMAFPDVCKEFFILKKEYEKEIDVEVTSAVELSEEQRAEISSKLEQRLARKVQLNCSIDETLLSGVIIRAGDLVIDNSARSRLDRLSDALQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta 1, ATP synthase F(1) sector subunit delta 1, F-type ATPase subunit delta 1, F-ATPase subunit delta 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MOCOS_SOLLC
Sequence: MNIESEKEQFLKEFGSYYGYANSPKNIDEIRATEFKRLNDTVYLDHAGATLYSESQMEAVFKDLNSTLYGNPHSQSTCSLATEDIVGKARQQVLSFFNASPREYSCIFTSGATAALKLVGETFPWSSNSSFMYSMENHNSVLGIREYALSKGAAAFAVDIEDTHVGESESPQSNLKLTQHHIQRRNEGGVLKEGMTGNTYNLFAFPSECNFSGRKFDPNLIKIIKEGSERILESSQYSRGCWLVLIDAAKGCATNPPNLSMFKADFVVFSFYKLFGYPTGLGALIVRKDAAKLMKKTYFSGGTVTAAIADVDFFKRREGVEEFFEDGTISFLSITAIQHGFKIINMLTTSSIFRHTTSIAAYVRNKLLALKHENGEFVCTLYGLLSSEMGPTVSFNMKRPDGTWYGYREVEKLATLAGIQLRTGCFCNPGACAKYLGLSHLDLLSNIEAGHVCWDDRDILHGKPTGAVRVSFGYMSTFEDAMKFVNFVESNFVISSFNRCALQPRSISLPIEGIAEAAARHFLTSITVYPIKSCAGFSVDQWPLTSTGLLHDREWILKSTTGEILTQKKVPEMCYISTLIDLNLGKLFVESPRCKEKLQIELKSSSLVTERDEMDIQNHRYEVTSYNNEVDIWFSRAIDRPCTLLRNSDSQSHSCINKNGSPGMCRDVGARLNFVNEAQFLLISEESIKDLNSRLKSNGRRRNGGQAVQVGVMRFRPNLVASSGEPYAEDGWSNINIGGKYFMSLGGCNRCQMININPEAGEVQRFTEPLATLAGYRRAKGKIMFGILLRYENNTKTESDTWIRVGEEIIPNGDRH
What is the function of this protein?
Sulfurates the molybdenum cofactor.  Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
What are the official names of this protein?
Molybdenum cofactor sulfurase, MCS, MOS, MoCo sulfurase, Molybdenum cofactor sulfurtransferase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
Protein: THYX_RICBR
Sequence: MNNATKRVVVPALEEILYEPIKVLDHGFIRVIDYMGDDSAIVQAARVSYGKGTKQLNQDKGLINYLLRHYHTTPFEMCDIKFHIKLPIFIARQWIRHRTASVNEYSARYSILGNEFYLPEPQNIAPQSSTNKQCRESDSLPKEVAEKVLNILEEDARNCYKHYTKLMNTDEEGNIIDDNNTGIARELARMNLTLNYYTEWYWKINLHNLLHFLRLRADPHAQYEIRVYAEKMLDIVKAWVPFTYEAFEEYRMCGANISRKGLEVIKKMISGEKVTHETSGMTKREWEELTKILK
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: TRPA_HYDCU
Sequence: MSRIDATLSALKSEKKTALIPYITAGDPHPDMTVNLMHSLVEQGADMIELGVPFSDPMADGPVIQKAVERALEHNVSLKNVLAYVTEFRKKDAQTPVILMGYLNPIEAMGSDVFAKAAAEAGVDAVLTVDMPPEESEGYFQDLSLAQLDRIFLVSPTTPDGRLNAVSEKGSGFVYYVSLKGVTGSKALDVDDVAQHVGHLREKMSMPVAIGFGIRDGNTAYEMAKLGDAIIVGSALVSLIEQNASEDSAVIQQVLSDKMREFRQAIDKADNE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: HSLV_VIBVU
Sequence: MTTIVSVRRNNKVVIAGDGQVSLGNTVMKGNARKVRRLYNNKVLAGFAGGTADAFTLFERFESKLQMHQGHLTKAAVELAKDWRSDRALRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGAYAQAAATALLENTELDAREIAEKALNIAGDICVFTNHNHTIEELEIPAELPNLSQA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAP2_PSEU2
Sequence: MDATTINSLFLIGALLVAASILVSSLSSRLGIPILVIILAVGMVAGVDGGGIIFDNYATAYLVGNLALAVILLDGGLRTRVASFRVALWPALSLATVGVLITTVLTGMMAAWLFNLSVIQGLLIGAIVGSTDAAAVFSLLGGKGLNERVTASLEIESGSNDPMAVFLTVTLIGMLASGQTGLHWGLLGHLIQEFGIGSFIGLGGGWILLQLVNRINLAAGLYPILVIAGGLAIFALTNAIHGSGFLAVYLCGLVLGNRPIRSRHGILHMLDGMAWLAQIGMFLVLGLLVTPHDLLPIAIPALGLALWMILVARPLSVMVGLLPFKAFHDREKAFIAWVGLRGAVPIILAVFPLMAGLPNAQLYFNLAFFIVLVSLLLQGTSLPWMAKLLKVTVPPDPAPISRAALEVHVTSEWELFVYRLGAEKWCIGAALRELKMPEGTRIAALFRGQQLLHPSGSTTLEVGDLLCVIGHEHDLPALGKLFSQAPQRGLDLRFFGDFVLEGDARLGEVAALYGLKLDGIDPGMPLSQFIVQKNRGEPVVGDQVEWNGTIWTVAVMDGNKIQKVGVKFPEGTRPGPGLFL
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2405_ALKCK
Sequence: MPLPGFTKSDFETFLIDGLEERMAAIRSNIQPKFQVIGAELRDELSTLLGNEMFLHIAQHARRTTNPPNDTWLAVAGNKRGYKKHPHFQVGLFDDHLFIWLAFIYELPEKGNIAKTFLENKPLIEEVVPSDYVVSIDHTKKEANPLSELDLTQSLERFRDVKKAEWLVGRHFAKGSETVENGEQLMEAIRQTVKTLLPLYQLSLTAGAPTR
What are the official names of this protein?
UPF0637 protein ABC2405.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: PTPRM_MOUSE
Sequence: MRTLGTCLVTLAGLLLTAAGETFSGGCLFDEPYSTCGYSQADEDDFNWEQVNTLTKPTSDPWMPSGSFMLVNTSGKPEGQRAHLLLPQLKENDTHCIDFHYFVSSKSNAAPGLLNVYVKVNNGPLGNPIWNISGDPTRTWHRAELAISTFWPNFYQVIFEVVTSGHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAGQFATFQCSAIGRTVAGDRLWLQGIDVRDAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMICTEGGVGISNYAELVVKEPPVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYGYQVGGQEQVREEVSWDTDNSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELTVQTDEDLPGAVPTESIQGSAFEEKIFLQWREPTQTYGVITLYEITYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKISAPSMPAYEFETPLNQTDNTVTVMLKPAQSRGAPVSVYQIVVEEERPRRTKKTTEILKCYPVPIHFQNASILNSQYYFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPHKSYRIYYQAASRANGETKIDCVRVATKGAVTPKPVPEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKRKLAKKRKETMSSTRQEMTVMVNSMDKSYAEQGTNCDEAFSFMGTHNLNGRSVSSPSSFTMKTNTLSTSVPNSYYPDETHTMASDTSSLAQPHTYKKREAADVPYQTGQLHPAIRVADLLQHITQMKCAEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYDHSRVRLQMLEGDNNSDYINGNYIDGYHRPNHYIATQGPMQETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTEIYKDIKVTLIDTELLAEYVIRTFAVEKRGIHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPNAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCGDTSIPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFLITIDGESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQLCPQYWPENGVHRHGPIQVEFVSADLEEDIISRIFRIYNASRPQDGHRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG
What is the function of this protein?
Receptor protein-tyrosine phosphatase that mediates homotypic cell-cell interactions and plays a role in adipogenic differentiation via modulation of p120 catenin/CTNND1 phosphorylation.  Promotes CTNND1 dephosphorylation and prevents its cytoplasmic localization where it inhibits SLC2A4 membrane trafficking.  In turn, SLC2A4 is directed to the plasma membrane and performs its glucose transporter function.
What are the official names of this protein?
Receptor-type tyrosine-protein phosphatase mu, Protein-tyrosine phosphatase mu, R-PTP-mu.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Localizes in regions of cell-cell contact.
Protein: YSZB_BACSU
Sequence: MKEETFYLVREDVLPDAMRKTLEVKKLLDRKKADSVADAVQKVDLSRSAFYKYRDAVFPFYTMVKEQIITLFFHLEDRSGALSQLLQAVADSGSNVLSIHQTIPLQGRANVTLSISTSAMEEDIHTLMNKLRKFDFVEKVEILGSGA
What are the official names of this protein?
UPF0735 ACT domain-containing protein YszB.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: ACHB4_CHICK
Sequence: STAADAEEKLMNHLLSPDRYNKLIRPAVNSSQLVSIELQVSLAQLISVNEREQIMTTNVWLNQEWIDYRLAWKPSDYEGINMLRIPAKHIWLPDIVLYNNADGTYEVSLYTNAIVQNNGSIRWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYDHTEIDMVLKTSMASMDDFTPSGEWDIVALPGRRTENPLDPNYVDVTYDFIIKRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMPPWVKLVFLERLPAYLFMKRPENNSPRQKPANCKKTRAENLCMDPADFYKNSTYFVNTASAKKYDMKITDTLDNVSSHQDFRLRTGTKFSPEVQEAIDGVSFIAEHMKSDDNDQSVIEDWKYVAMVVDRLFLWIFVLVCVLGTVGLFLQPLFQNHIAATNP
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit beta-4, Neuronal acetylcholine receptor non-alpha-3 chain, N-alpha 3.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-4/CHRNB4 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: ACPS_MYCBT
Sequence: MGIVGVGIDLVSIPDFAEQVDQPGTVFAETFTPGERRDASDKSSSAARHLAARWAAKEAVIKAWSGSRFAQRPVLPEDIHRDIEVVTDMWGRPRVRLTGAIAEYLADVTIHVSLTHEGDTAAAVAILEAP
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLC1_HUMAN
Sequence: MYDNMSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGEEVSMSVEWNGGVSGRASFCGKRQQQQWPGRRHR
What is the function of this protein?
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport (PubMed:21385839).  The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity).
What are the official names of this protein?
Kinesin light chain 1, KLC 1.
What is the protein family that this protein belongs to?
Belongs to the kinesin light chain family.
Protein: RL36_WOLPM
Sequence: MKVKGSLKSHRNRDKNCKVVKRGGKIYIINKVKPRCKARQGS
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RL24_ECO24
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: TATA_XANC5
Sequence: MGGFSIWHWLIVLVIVLLVFGTKRLTSGAKDLGSAVKEFKKGMHDDDKPAGKLGDDSRTAEQAREAQAERDRDAR
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NU4M_USTMA
Sequence: MLTLLLIIPLVGALMLAPMQGNTRQSESQMKRLALGTSLINFVLSIVLWGEFDSSTSEYQFTQEFNQVNFCHLHIGVDGISLYFVLLTTFITPICILSNWDNIKEQLKYFLMCFLVLETLLIAVFVVLDILLFYVFFESVLIPLFLIVGIWGGSATRVRAAFLLFLYTLFGSLFMLLAFLVIYYNVGSTDFQVVSLSEINLESQKLLWLAVFISMAIKTPLLPFHVWLPRAHAEAPLAGSVILAGLILKLATYGYMRILIQFLPDATSYFSPLVQTIAVITLIYASLATLRQTDFKALVAYSSIGHMAVVVLGLFSNTIQGIDGALLLSIAHGVVSPALFILVGGVLYDRYHTRTIRYYRGMTAYMPLFSIMFFVFTIFNAAVPLSANWAGEFLCLAGAFQRNPVFAVLGSTGIVLSAAYSIWLYNRIAFGAWSKYLNYTTDLTRREFMLLLPLLFVAVVFGIFPNIILDSIHASTSGLIYSAS
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y4574_CAUSK
Sequence: MKDLGGLMKQAQAMQQKLADAQARLAELTVEGTSGGGMVTVTLRGNGELAKVVLDESLIEPGEGEVIADLIVAAHADAKKKLDAQQAQLMQEAAGPMAGMMGGLPGMKF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Caul_4574.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: METK_SULIK
Sequence: MRNINVQLNPLSDIEKLQVELVERKGLGHPDYIADAVAEEASRKLSLYYLKKYGVILHHNLDKTLVVGGQATPRFKGGDVIQPIYIVVAGRATTEVKTESGIEQIPVGTIIIESVKEWIRNNFRYLDAEKHLIVDYKIGKGSTDLVGIFEAGKRVPLSNDTSFGVGFAPFTKLEKLVYETERHLNSKQFKAKLPEVGEDIKVMGLRRGNEVDLTIAMATISELIEDVNHYINVKEQAKNEILDLASKIAPDYDVRIYVNTGDKIDKNILYLTVTGTSAEHGDDGMTGRGNRGVGLITPMRPMSLEATAGKNPVNHVGKLYNVLANLIANKIAQEVKDVKFSQVQVLGQIGRPIDDPLIANVDVITYDGKLNDETKNEISGIVDEMLSSFNKLTELILEGKATLF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase 2 family.
Protein: LEU1_SALA4
Sequence: MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIATSPMHIATKLRSTLDEVIERAVYMVKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAINAGARTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAVHAGARQVEGAMNGIGERAGNCALEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMEEMGYKDTDYNMDHLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGSSDIATASVKLACGEEIKAEAANGNGPVDAIYQAINRLTGYDVELVKYDLNAKGQGKDALGQVDIVVNHHGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: VSPC1_CROAT
Sequence: VVGGDECNINEHRSLVAIFVSTEFDCGGDLINVEWVLTAAHCTLCAGIPEGGLDTCGGDSGGPLICDGKPDGITS
What is the function of this protein?
Thrombin-like snake venom serine protease.  Clots fibrinogen (FGA and FGB) very slowly, releasing fibrinopeptide A and a small amount of fibrinopeptide B.
What are the official names of this protein?
Thrombin-like enzyme catroxobin-1, SVTLE, Catroxobin I, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DPB2_YEAST
Sequence: MFGSGNVLPVKIQPPLLRPLAYRVLSRKYGLSIKSDGLSALAEFVGTNIGANWRQGPATIKFLEQFAAVWKQQERGLFIDQSGVKEVIQEMKEREKVEWSHEHPIQHEENILGRTDDDENNSDDEMPIAADSSLQNVSLSSPMRQPTERDEYKQPFKPESSKALDWRDYFKVINASQQQRFSYNPHKMQFIFVPNKKQNGLGGIAGFLPDIEDKVQMFLTRYYLTNDRVMRNENFQNSDMFNPLSSMVSLQNELSNTNRQQQSSSMSITPIKNLLGRDAQNFLLLGLLNKNFKGNWSLEDPSGSVEIDISQTIPTQGHYYVPGCMVLVEGIYYSVGNKFHVTSMTLPPGERREITLETIGNLDLLGIHGISNNNFIARLDKDLKIRLHLLEKELTDHKFVILGANLFLDDLKIMTALSKILQKLNDDPPTLLIWQGSFTSVPVFASMSSRNISSSTQFKNNFDALATLLSRFDNLTENTTMIFIPGPNDLWGSMVSLGASGTLPQDPIPSAFTKKINKVCKNVVWSSNPTRIAYLSQEIVIFRDDLSGRFKRHRLEFPFNESEDVYTENDNMMSKDTDIVPIDELVKEPDQLPQKVQETRKLVKTILDQGHLSPFLDSLRPISWDLDHTLTLCPIPSTMVLCDTTSAQFDLTYNGCKVINPGSFIHNRRARYMEYVPSSKKTIQEEIYI
What is the function of this protein?
As accessory component of the DNA polymerase epsilon complex participates in chromosomal DNA replication.  It is required during synthesis of the leading and lagging DNA strands at the replication fork and binds at/or near replication origins and moves along DNA with the replication fork.  It has 3'-5' proofreading exonuclease activity that correct errors arising during DNA replication.  It is also involved in DNA synthesis during DNA repair.
What are the official names of this protein?
DNA polymerase epsilon subunit B, DNA polymerase II subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase epsilon subunit B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MOAC_SHIDS
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEADD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: SECB_KLEP3
Sequence: MSEQNSTEMTFQIQRIYTKDISFEAPNAPQVFQKDWQPEVKLDLDTASTQLAEGVYEVVLRVTVTAALGEETAFLCEVQQGGIFSIDGIEGTQMAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGAEQHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPRA_BACSU
Sequence: MDQAAVCLTICRINQLLSPSLLLKWWKADPSMSLTSPVLQTVTRDQIKAAALKNEIEQFYPKLPRVLAAYREQGINTIPISSKQYPFWLKSIYDPPAVLFAKGDMTLLSKGRKIGIVGTRNPTAYGKQVVNHLTKEICRKGWVIVSGLASGIDGMSHAASIKAKGRTIGVIAGGFQHIYPRENLQLADHMAKHHILLSEHPPETKPQKWHFPMRNRIISGLSEGVIVVQGKEKSGSLITAYQALEQGREVFAVPGSLFDPYAGGPIKLIQQGAKAIWSAEDIFEELPERNVQYTEPF
What is the function of this protein?
Protein that helps load RecA onto ssDNA during transformation (PubMed:17803906, PubMed:25138221).  Binds cooperatively to circular ssDNA, is able to bridge different segments of DNA (PubMed:17803906).  Favors the loading of RecA onto SsbA- or SsbB-coated ssDNA and formation of RecA-DNA filaments (PubMed:25138221).  RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP (PubMed:25138221).
What are the official names of this protein?
DNA processing protein DprA, Protein Smf.
What is the protein family that this protein belongs to?
Belongs to the DprA/Smf family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes mostly to the cell poles during the development of competence (PubMed:17630974). During competence a number of proteins (at least CoiA, ComFA, ComGA, DprA, RecA and SsbB) are thought to colocalize at the cell pole, in a disruption of ssbB DprA no longer accumulates (PubMed:17630974).
Protein: RSPH3_HUMAN
Sequence: MTVKPAKAASLARNLAKRRRTYLGGAAGRSQEPEVPCAAVLPGKPGDRNCPEFPPPDRTLGCWATDAAPAAGLCGAGSEPSIAPTSCAGNLPSRPPPLLSPLLASRNPCPWHYLHLSGSHNTLAPTCFKAKLHRKRGSQPPDMASALTDRTSRAPSTYTYTSRPRALPCQRSRYRDSLTQPDEEPMHYGNIMYDRRVIRGNTYALQTGPLLGRPDSLELQRQREARKRALARKQAQEQLRPQTPEPVEGRKHVDVQTELYLEEIADRIIEVDMECQTDAFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVMEEEELANLRASQREYEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQKIAARAFAQRYLADLLPSVFGSLRDSGYFYDPIERDIEIGFLPWLMNEVEKTMEYSMVGRTVLDMLIREVVEKRLCMYEHGEDTHQSPEPEDEPGGPGAMTESLEASEFLEQSMSQTRELLLDGGYLQRTTYDRRSSQERKFMEERELLGQDEETAMRKSLGEEELS
What is the function of this protein?
Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia (By similarity).  Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme.  May serve as a point of convergence for MAPK and PKA signaling in cilia (PubMed:19684019).
What are the official names of this protein?
Radial spoke head protein 3 homolog, A-kinase anchor protein RSPH3, Radial spoke head-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the flagellar radial spoke RSP3 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium.
Protein: MURB_BURA4
Sequence: MPMPPDDSALSLLPDHPLAAHNTFGIDATARFAARVTHAAQFAALHRDPRVAHLSQLVLGGGSNVVFTRDFDGVVLLDEIAGRRVVREDDDAWYVEAGGGETWHAFVAWTLEHGMPGLENLALIPGTVGAAPIQNIGAYGLEMKTYFDSLVAVELATGRSERFDAARCAFGYRDSFFKREGRGRFAIVAVTFRLPKRWTPRLGYADVTRELDARGIAPDAATPRDVFDAVVAIRRAKLPDPLELGNAGSFFKNPVIDAAQFDALRARVPDVVSYPQPGGQVKLAAGWLIDRCGWKGRTLGAAAVHDRQALVLVNRGGATGADVLALARAIQDDVRKQFGVELEPEPVCV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERC_XANCP
Sequence: MPEAAPPVADARGSSPTATTGPGADATLSAVEPFLAHLQIERQVSAHTLDAYRRDLAALIGWASAQGSEDVAQLDSAQLRKFVTAEHRRGLSPKSLQRRLSACRSYYAWLLKHGRIATSPAAALRAPKAPRKLPQVLDADEAVRLVEVPTDAPLGLRDRALLELFYSSGLRLSELCALRWRDLDLDSGLVTVLGKGGKQRLVPVGSHAVAALRAWQRDSGGSAQTHVFPGRAGGAISQRAVQIRIKQLAVRQGMFKHVHPHMLRHSFASHILESSGDLRGVQELLGHSDIATTQIYTHLDFQHLAKVYDAAHPRAKRKKATE
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.