PharMolix/UniProtQA huggingface dataset:
Protein: K319L_HUMAN
Sequence: MEKRLGVKPNPASWILSGYYWQTSAKWLRSLYLFYTCFCFSVLWLSTDASESRCQQGKTQFGVGLRSGGENHLWLLEGTPSLQSCWAACCQDSACHVFWWLEGMCIQADCSRPQSCRAFRTHSSNSMLVFLKKFQTADDLGFLPEDDVPHLLGLGWNWASWRQSPPRAALRPAVSSSDQQSLIRKLQKRGSPSDVVTPIVTQHSKVNDSNELGGLTTSGSAEVHKAITISSPLTTDLTAELSGGPKNVSVQPEISEGLATTPSTQQVKSSEKTQIAVPQPVAPSYSYATPTPQASFQSTSAPYPVIKELVVSAGESVQITLPKNEVQLNAYVLQEPPKGETYTYDWQLITHPRDYSGEMEGKHSQILKLSKLTPGLYEFKVIVEGQNAHGEGYVNVTVKPEPRKNRPPIAIVSPQFQEISLPTTSTVIDGSQSTDDDKIVQYHWEELKGPLREEKISEDTAILKLSKLVPGNYTFSLTVVDSDGATNSTTANLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPSSKGKVVEMQGVRTPTLQLSAMQEGDYTYQLTVTDTIGQQATAQVTVIVQPENNKPPQADAGPDKELTLPVDSTTLDGSKSSDDQKIISYLWEKTQGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPIAKITGNVVITLPTSTAELDGSKSSDDKGIVSYLWTRDEGSPAAGEVLNHSDHHPILFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKPDPRKNNLVEIILDINVSQLTERLKGMFIRQIGVLLGVLDSDIIVQKIQPYTEQSTKMVFFVQNEPPHQIFKGHEVAAMLKSELRKQKADFLIFRALEVNTVTCQLNCSDHGHCDSFTKRCICDPFWMENFIKVQLRDGDSNCEWSVLYVIIATFVIVVALGILSWTVICCCKRQKGKPKRKSKYKILDATDQESLELKPTSRAGIKQKGLLLSSSLMHSESELDSDDAIFTWPDREKGKLLHGQNGSVPNGQTPLKARSPREEIL
What is the function of this protein?
(Microbial infection) Acts as a receptor for adeno-associated virus and is involved in adeno-associated virus infection through endocytosis system.
What are the official names of this protein?
Dyslexia-associated protein KIAA0319-like protein, Adeno-associated virus receptor, AAVR.
What are the subcellular locations of this protein?
Cytoplasmic granule membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Traffics from the plasma membrane to the trans-Golgi network.
Protein: CCA_AZOVD
Sequence: MRIYKVGGAVRDRLLGRPVSEVDWVVVGASAEELLALGYRPVGADFPVFLHPRTGEEYALARTERKSGRGYGGFTFHASPEVTLEEDLLRRDLTINAMAEDEQGRLIDPCHGRRDLEQRWLRHVSPAFAEDPLRVLRVARFAARYAPLGFRVAPETRALMRQLAESGELQALTAERSWKEISRALLEPRPDVFIRTLRDCGALHELLPEIDALFGVPQPAAHHPEIDTGEHLLAVLRQCAEHGQPLVVRWACLLHDLGKGTTPAEEWPRHIAHERKGLKLIRAVNTRCKAPRDCQELSLLVGEYHSHCHRALELRPATLLELLQRFDVYRRPQRFEEFIAACEMDARGRLGLERRDYPQAGYLRGAAAAARAVAVQPLLEKGLAGAALGEALKRERLRALKAYKSDVLGERAEPPETS
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: ARLY_LEPIN
Sequence: MTEKEKKLWGGRFQENASSILERIGQSISFDHKLYKEDIQGSIAHARMLKQIGILNSEELSKIEIALAQIKTELEEGKFEFKSELEDIHMHIEFRLTELIGETGKKLHTARSRNDQVTQDVRLYILNQGKEILKSIINLRSSLYQKAKQSLDVIIPGYTHLQIAQPIRASQYLLSWFWALERDQEFFRFAFKASEELALGSGAMAGVNYPTDREFLKKELGLSKVSPNSMDGVSSRDHILEFLFACTQLMIHVSRICEDIILYSSQEFGILKLPDSLTTGSSIMPQKKNPDIAELIRGKSGRVIGNLNHLLVMLKGLPSTYNRDLQEDKLALFDSIETVQISLEGIREMIEGWIWIPERAEVSLKNGFATATDLADFLVNEKKIPFRTAHELVGTLVGVCVKQKKTLFDLPESDRVSISKYFVGKEYEDAVSLSLSADKKISYGGTSKKRQEEQLKIALDSLKEAERLFL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDA_ECO55
Sequence: MNTPAQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: TXH23_CYRSC
Sequence: MKVTLIAILTCAAVLVLHTTAAEELEESQLMEVGMPDTELAAVDEERLFECSISCEIEKKGESCKPKKCKGGWKCKFNMCVKV
What is the function of this protein?
Lethal neurotoxin that blocks neuromuscular transmission.
What are the official names of this protein?
U1-theraphotoxin-Hs1f, U1-TRTX-Hs1f, Huwentoxin-2a, Huwentoxin-IIa.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LGUL_SHIFL
Sequence: MRLLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYSLAFVGYGPETEEAVIELTYNWGVDKYELGTAYGHIALSVDNAAEACEKIRQNGGNVTREAGPVKGGTTVIAFVEDPDGYKIELIEEKDAGRGLGN
What is the function of this protein?
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
What are the official names of this protein?
Lactoylglutathione lyase, Aldoketomutase, Glyoxalase I, Glx I, Ketone-aldehyde mutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.
Protein: MTRD_METBF
Sequence: MIDAILGNIIWMALITIGGVLISWSVHFVPVGGAPAAMAQATGIGTGTVQLAAGAGLTGLVSAGFMMNVTDNLPLILASGSVGAMIMIAVTMIVGSIVYVYGVGVVPSSAKVKVDPITKYRQDLYVSQGTEGHGLPTVSYVSGIIGGGLGGIGGSLVYYSLIEVGMSAGLEAVGVTNSVTGHELVAVAAIFAIGIFFVNAVIPSYNIGGTIEGFHDPKFKKWPKAVVSSLVASIMCAIVAVVAIAQLGGI
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit D, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit D.
What is the protein family that this protein belongs to?
Belongs to the MtrD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: METE_CAMJR
Sequence: MKNSIISYPRIGANRELKFAIEKYFKNQSSKEELLKSAKDLRIRHWQEIQKAGIDFIPSNDFSLYDNVLDAAVLFNIVHTKYKNLNLDALDEYFAQSRGYQGENGDVTALAMKKWFNTNYHYLVPECDNADIIALTGDKIFKEYLEAKELGIESKPVLIGIFTLFKLIAFKDEKTQKLAKEKLLNAYIELFDKLNELKVTWLELDEPYLVYDLSKEDIALFEEFYQELLNHKKDLKILLQSYFGDLRDIYPKLLESKFDALGLDFIEGKQSLALVQKYGFAKDKILFAGLINGKNIYTNDYAKSLKLIKELQKYTQNIILNTSCSLLHVPYSTEFESKLDSNYLKLFSFAKEKLQELKDLKEILNSSEENPLFRANQELFKNIPERLDEKVKARLKALKKEDFTRTPSFKERALIQKEFLKLPLLPTTTIGSFPQSADVRSNRLAFKQEKISAQNYTEFNQQKIKECIQIQEEIGLDVLVHGEFERNDMVEYFGENLKGFLFTQNGWVQSYGTRCVKPPVIWGDVSRTKPITLAWSKFAQSLSQKIVKGMLTGPVTILNWSFPREDISLKESTEQIALAIRDEVLDLENAGIKIIQIDEAALREKLPLRKSDWHSEYLDWAIPAFNLVHSGVKAKTQIHTHMCYSEFSDILKEIDAMDADVISFEASRSNLSLLDTLKAIRFKTEVGPGVYDIHSPRVPSVEELSLTIEKILNKLPKEQIWINPDCGLKTRAYEEVIASLKNLVTATQKIREQL
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: DAPB_DESPS
Sequence: MTKVIIAGASGRMGQRVAHMVEAHPELEYAAAFEAAGNPAIGKDIGRIVFGEENGVIVGEGLESVIADGDVIIDFTFHTATMEFARIAAKHGKAMVIGTTGLSVDELAELKDLSASFPCVQAPNMSVCVNVLFKLAKKTAAILGDDYDIEILEAHHNKKKDAPSGTALKLAEMAAEGVGRNLAEVGVYERNGIIGERDPKEIGIQTLRAADIVGEHTIYFAGAGERLEISHRAHSRDHFAKGAATAAAWLVGRENGIYDMFDVLGLQDL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_RHORT
Sequence: MSFFRVAVMLAAMTGLFLAVGYLIGGQSGMVIAFLVAGGMNLFAYWNSDKMVLRMHNAREVDERSAPDLYGIVRQLTQRGGLPMPKVYVIDTPQPNAFATGRNPQNAAVAATTGLMRALTPQELAGVMAHELAHVRHHDTLTMTLTATLAGAISMLANFAFFFGGNRDNNNPLGAVGMIVMMILAPLAAMMVQMAISRTAEYRADRGGAEICGQPLWLASALEKIERAARGIENPSAEQNPATAHLFIINPLNGHRMDNLFTTHPSTANRVAKLRALASGDLAQPRPQRGPWG
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBA_PROM9
Sequence: MTTIQQQRSSLLKGWPQFCEWVTSTNNRIYVGWFGVLMIPCLLAAAACFIVAFIAAPPVDIDGIREPVAGSFLYGNNIISGAVVPSSNAIGLHFYPIWEAATVDEWLYNGGPYQLVIFHFLIGISAYMGRQWELSYRLGMRPWICVAYSAPVSAAFAVFLVYPFGQGSFSDGMPLGISGTFNFMFVFQAEHNILMHPFHMAGVAGMFGGSLFSAMHGSLVTSSLIRETTETESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAVFPVVCVWLTSMGICTMAFNLNGFNFNQSVVDANGKIVPTWGDVLNRANLGMEVMHERNAHNFPLDLAAAESTTVALSAPAIG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: HGD_XANC5
Sequence: MPMHDQTSYMTGFGNEFATEAVAGSLPVGQNSPQRVAHGLYAEQLSGTAFTAPRGENRRSWLYRIRPAAVHGRFSLIEQSRLHNDFGGGPVPPDQMRWSPLPLPATRTDFVDGLYTMAGNGSPEAMTGVAVHLYAANASMRDRFFYNADGELLLVPQLGRLRVCTELGVLELEPQQIGVIPRGLRFRVELLDSEARGYVCENFGGLLRLPELGPIGANGLANPRDFQTPRAAFEQREGRFELVAKFQGHLWRADIGHSPLDVVAWHGNYAPYRYDLRRFNTIGSISFDHPDPSIFTVLTSPSDTHGTANMDFAIFPPRWLVAQHTFRPPWFHRNVASEFMGLVHGVYDAKAEGFAPGGASLHNCMSGHGPDAATFDKASQADLTRPDVIADTMAFMFETRAVLRPTQQALNAAHRQADYQQCWSGLRAAFQPPTTEDAT
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: TTYH2_HUMAN
Sequence: MQAARVDYIAPWWVVWLHSVPHVGLRLQPVNSTFSPGDESYQESLLFLGLVAAVCLGLNLIFLVAYLVCACHCRRDDAVQTKQHHSCCITWTAVVAGLICCAAVGVGFYGNSETNDGAYQLMYSLDDANHTFSGIDALVSGTTQKMKVDLEQHLARLSEIFAARGDYLQTLKFIQQMAGSVVVQLSGLPVWREVTMELTKLSDQTGYVEYYRWLSYLLLFILDLVICLIACLGLAKRSKCLLASMLCCGALSLLLSWASLAADGSAAVATSDFCVAPDTFILNVTEGQISTEVTRYYLYCSQSGSSPFQQTLTTFQRALTTMQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGICYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQAWRMAAHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIGRASPPPTYSPSMRATYLSVADEHLRHYGNQFPA
What is the function of this protein?
Probable large-conductance Ca(2+)-activated chloride channel.  May play a role in Ca(2+) signal transduction.  May be involved in cell proliferation and cell aggregation.
What are the official names of this protein?
Protein tweety homolog 2, hTTY2.
What is the protein family that this protein belongs to?
Belongs to the tweety family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URE1_STAEQ
Sequence: MSFKMTQSQYTSLYGPTVGDSVRLGDTNLFAQVEKDYANYGDEATFGGGKSIRDGMAQNPNVTRDDKNVADLVLTNALIIDYDKIVKADIGIKNGYIFKIGKAGNPDIMDNVDIIIGATTDIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIGGGTGASEGAKATTVTPGPWHIHRMLEAAEEMPINVGFTGKGQAVNHTALIEQIHAGAIGLKVHEDWGATPSALSHALDVADEFDVQVALHADTLNEAGFMEDTMAAVKDRVLHMYHTEGAGGGHAPDLIKSAAYSNILPSSTNPTLPYTHNTVDEHLDMVMITHHLNASIPEDIAFADSRIRKETIAAEDVLQDMGVFSMVSSDSQAMGRVGEVVTRTWQVAHRMKEQRGPLDGDFEYHDNNRIKRYIAKYTINPAITHGISDYVGSVEAGKLADLVMWEPEFFGAKPDLVVKGGMINSAVNGDANGSIPTSEPLKYRKMYGQFGGNITHTAMTFVSNTAYENGIYRQLNLKRMVRPVRNIRNLTKADMKNNNATPKIDVDPQTYEVFVDGNKITSEAATELPLTQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_BRADI
Sequence: MKNVTHSFVFLAHWPSAGSFGLNTDILATNLINLTVVVGVLIFFGKGVLKDLLDNRKQRILSTIRNSEELRRGTFEQLEKARIRLQKVELEADEYRMNGYSEIEREKENLINATSISLEQLEKSKNETLYFEKQRAMNQVRQRVFQQAVQGALGTLNSCLNTELHFRTIRANIGILGSMEWKR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CHER1_ARATH
Sequence: MRGPLGAVIGRYTSSDGSAPNDGIIKHNRKCRDITFLIIFIAFWVSMIVNSSFGFNQGNPLRLTYGLDYEGNVCGSKHRHRDLTQLELRYWLNPNQVYESGLKDGELKLANARTICLLDCPAPSDDTLNWVCDYPDGEIRLKMNDWIDRNYDYFEFLTPEMRNSSLQLQGPCYPVIFPSVNVYWSCQYIARASNSSLRHWQQMGGVNIQEDMIIDKSIRRSMNSRASVLKRYVADIGKSWPVLIVCGGLVPLFLSIIWLLLIRHFVAAMPWITVVLFNMLLISVTVFYYLKAGWIGNDAVTPIIGEHDPYFHVYGRELTHVRGVAILMTFISVVAILTSIAIIRRILMATSVLKVAAKVIGEVQALIIFPAIPFAMLAIFYMFWISAALHLFSSGQVVQNNCNNTNCCAYDLVLKKVNCDRCCGYSIHYTPHITIAIFFHLFGCYWATQFFIASSATVIAGSVASYYWAQGEASPEIPFLPVFASMKRLARYNLGSVALGSLIVSFVESVRFILEAIRRKTKVSGTIPDHWFWRMAHYTSRGCLKSVEWTIKSVNRNAYIMIAITGKSFCKSSAIATELIISNILRIGKVNVIGDVILFLGKLCVSLFSALFGFLMLDSHRYRASHNKVSSPLLPVLACWALGYIVATLFFAVVEMSIDTIILSFCQDSEENQGNAQHAPPLLLETLDSNQEEEVQSLTH
What is the function of this protein?
(Microbial infection) Required for PD localization of MP17, the luteoviral movement protein.
What are the official names of this protein?
Choline transporter protein 1, AtCTL1, Protein SIGNIFICANT IONOME CHANGES 1.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Early endosome membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton, phragmoplast. Prevacuolar compartment membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Associated transiently with the phragmoplast during cytokinesis. Follows a polar localization in the forming sieve plates.
Protein: IKZF3_HUMAN
Sequence: MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDDSMKVKDEYSERDENVLKSEPMGNAEEPEIPYSYSREYNEYENIKLERHVVSFDSSRPTSGKMNCDVCGLSCISFNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHTGEKPFKCHLCNYACQRRDALTGHLRTHSVEKPYKCEFCGRSYKQRSSLEEHKERCRTFLQSTDPGDTASAEARHIKAEMGSERALVLDRLASNVAKRKSSMPQKFIGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGEHRALLK
What is the function of this protein?
Transcription factor that plays an important role in the regulation of lymphocyte differentiation.  Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state.  Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner.
What are the official names of this protein?
Zinc finger protein Aiolos, Ikaros family zinc finger protein 3.
What is the protein family that this protein belongs to?
Belongs to the Ikaros C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. SUBCELLULAR LOCATION: [Isoform 1]: Nucleus. SUBCELLULAR LOCATION: [Isoform 3]: Nucleus. SUBCELLULAR LOCATION: [Isoform 11]: Nucleus. SUBCELLULAR LOCATION: [Isoform 14]: Nucleus. Cytoplasm. SUBCELLULAR LOCATION: [Isoform 12]: Cytoplasm.
Protein: HE71B_XENLA
Sequence: MKGTSEVKPMETHRKLLKPLVEKRRRERINNSLEKLRIFLSQTLKSEKLKNPKVEKAEILECTVQFLQSRKLLPLDREAVDKEYQSGFQHCLETTLHFMNSKPDMNGVTKELLSHQMSSCKPPSDAWSPTCAPLTKHVPSLSYQDSTPHLVSNSISISPTKTLVDSHFTYQTFKTWRPWV
What is the function of this protein?
Transcriptional repressor.  Represses transcription from both N box- and E box-containing promoters (By similarity).  Demarcates the prospective midbrain-hindbrain boundary (MHB) region in the neuroectoderm in early gastrulae embryos by repressing transcription of a number of target genes.
What are the official names of this protein?
Transcription factor HES-7.1-B, HES-related protein 1-B, XHR1-B, Hairy and enhancer of split 7.1-B.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROK_ALTMD
Sequence: MAEKRNIFLVGPMGAGKSTIGRHLADELHLDFFDSDQEIERRTGADIAWIFDLEGEDGFRAREENVINDLTDKQGIVLATGGGSIVTKAVRNRLSARGIVVYLQTTIDKQVARTQRDKRRPLLQNEDPEQVLRDLAEMRNPLYEEVADYIVDTDDQSARAVANQIISKIGL
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS81_METCA
Sequence: MNPYWSALVRDLKPYVPGEQPKLDNLVKLNTNENPYPPSPKVLAAIRGELGASLRLYPDPNAELLKQAIARYHGVGANQVFVGNGSDEVLAHAFQALLKQTRPILFPDITYSFYPVYCGLYDIAHETVPLTESFEIRIEDYLRPNGGVVFPNPNAPTGRLLPLADIETLLSKNRDSVVIVDEAYIDFGGESAAALVNRFPHLLVIQTLSKSRSLAGLRVGFALGEPGLIEALERVKGSFNSYPLDRLAIVGGVAAFDDRDHFEWSRQAIMWTRQWLSRGLAELGFEVLPSAANFVFVRHPRHDGAELAAALRDRHIIVRHFKLPRIDQFLRITVGTEGECQILLDALSELVAGQAAA
What are the official names of this protein?
Histidinol-phosphate aminotransferase 1, Imidazole acetol-phosphate transaminase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: TRMFO_STAS1
Sequence: MTQVVNVVGAGLAGSEAAYQLAQRGVKVNLIEMRPVKQTPAHHTDKFAELVCSNSLRGNALTNAVGVLKEEMRQLDSLIISAADKARVPAGGALAVDRHDFAGYVTETLKNHPNITVLNEEINSIPEGYTIIATGPLTTDKLANEIVEATGKDQLYFYDAAAPIIEKDSIDMNKVYLKSRYDKGEAAYLNCPMTEDEFNTFYDALMEAEVAPVNEFEKEKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGERPYAVVQLRQDDAAGTLYNIVGFQTHLKWGAQKDVIRLIPGLENVEIVRYGVMHRNTFINSPDVLTETYELKGREELYFAGQMTGVEGYVESAASGLVAGINVAHKMLNKGEVIFPRETMIGSMAYYISHAKNEKNFQPMNANFGLLTTLEKKVKDKKLRYEKLADRALTYLDNYKQTL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLYA_ECODH
Sequence: MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISEMEAVINKTRAEILHGISAEELEQLITLIAKLEHNIIELQAKG
What is the function of this protein?
Transcription regulator that can specifically activate or repress expression of target genes.
What are the official names of this protein?
Transcriptional regulator SlyA.
What is the protein family that this protein belongs to?
Belongs to the SlyA family.
Protein: RL6_GEOKA
Sequence: MSRVGKKPIEIPAGVTVTVNGNTVTVKGPKGELTRTFHPDMTITVEGNVITVTRPSDEKHHRALHGTTRSLLANMVEGVSKGYEKALELVGVGYRASKQGKKLVLSVGYSHPVEIEPEEGLEIEVPSQTKIIVKGADKQRVGELAANIRAVRPPEPYKGKGIRYEGELVRLKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: NFUA_SALPC
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYALQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: MATK_GOSSC
Sequence: MEEFQVYLELNRSRRHDFLYPLIFREYIYALAHEHGLNKSMIFFENQGYGNKFSSLIVKRLILRMDQQNRLISSANDSNQNPVFGHNNNLYSQMIAAGFAVIVEIPFSLRLISYSQGAEAAKSHNFQSIHSIFPFLEDKFSHLNYVLEALIPHPIHLEILVQALRYWVKDASSLHLLRFSLYEYCNLKSFITPKKSISIFNPRLFLFLYNSHTCEYESIFLFLRNQSSHLRSTSSGVFLERIFFYGKIKYLGEVFYNDFQNNLWLFKDPFIHFIRYQGKSILASKDTSLLINKWKYYFVDLWQYYFYLWSQSGRVRINQLSKYSLDFLGYLSSVRLNPSVVRSQMLENSFLIDNAVKTLDTRIPIISIIGSLSKAKFCNTLGHPISKPTWADSPDSDIIDRFVRISRNLSHYHSGSSKKKSLYRIKYILRFSCVKTLARKHKSTVRAFLKKLGSEFLEEFFTETEEEHVFSLIFPRGFFALRKVYRGRIWYLDIICINALVNHS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IPIL2_HUMAN
Sequence: MSVHYTLNLRVFWPLVTGLCTALVCLYHVLRGSGGARAEPADGVDGGFPLLKVAVLLLLSYVLLRCRHAVRQRFLPGSPRLEGHAAFSSRHFREPGLSILLESYYEHEVRLSPHVLGHSKAHVSRIVGELVRAGRARGSPGLIPGGALALAFRGDFIQVGSAYEQHKIRRPDSFDVLVPLRLPPLVALEPRSLGEEPALAPAFRGCFLCALKAPPSPSGASGGHWLRDCKPFADAFCVDVRGRRHLSATLVLRWFQSHLQRSLATVRYSLEGRCRVTLTPGGLEQPPTLHILPCRTDYGCCRLSMAVRLIPAVHLGDGVFLVAPPPPPLPSAPLLELPEGLRAEALWGVNTARQEQKLLSWLQERAAPGACYLKCLQLLKALRDLGARGLDSAAATQWGRILSSYVLKTVLLAVLLRKGAPGQGWDEEHLGRCLEELVQFLRDCLLRRHTLFHCVLGPGGAAAEVGPLPKALREAAPVDLLAAFDGHARELAAARLLSTWQRLPQLLRAYGGPRYLARCPPPRSQRTQGFLEGEP
What are the official names of this protein?
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2.
What is the protein family that this protein belongs to?
Belongs to the ITPRIP family.