PharMolix/UniProtQA huggingface dataset:
Protein: BDBC_BACSU
Sequence: MKNRIVFLYASWVVALIAMLGSLYFSEIRKFIPCELCWYQRILMYPLVLILGIATFQGDTRVKKYVLPMAIIGAFISIMHYLEQKVPGFSGIKPCVSGVPCSGQYINWFGFITIPFLALIAFILIIIFMCLLKGEKSE
What is the function of this protein?
Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC.  Not normally required for production of the secreted lantibiotic sublancin 168, although it can partially substitute for BdbB when the latter is absent.  It may also be required for the stability of other secreted proteins.  Not required for sporulation.
What are the official names of this protein?
Disulfide bond formation protein C, Disulfide oxidoreductase C, Thiol-disulfide oxidoreductase C.
What is the protein family that this protein belongs to?
Belongs to the DsbB family. BdbC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Protein: Y294_MYCPN
Sequence: MDLLTTANKTPRIAKSRPVRIAIIITQKTNDLHATVPCFLWRKARYAVDLISAEAKASIMLEMGIHVRCDNTLSKTNFNQYTAAFIPHGNTTRLVEIDKLRKDLEKFVYKPKGPMRWLFSSGNGACVLKEFDLIAPDQLVTVQNEKEMVKLLGKNFIKQPVHVDKNIISCANSCGLTKFSFKVIEELSGIELARKTANLVDHIYKG
What are the official names of this protein?
Uncharacterized protein MPN_294.
Protein: NIP22_MAIZE
Sequence: MAAASTTSRTNSRVNYSNEIHDLSTVQSGSVVPTLFYPDKSIADIFPPHLGKKVISEVVATFLLVFVTCGAASIYGEDNRRISQLGQSVAGGLIVTVMIYATGHISGAHMNPAVTLSFACFRHFPWIQVPFYWAAQFTGAMCAAFVLKAVLHPIAVIGTTTPSGPHWHALLIEIVVTFNMMFVTCAVATDSRAVGELAGLAVGSAVCITSIFAGPVSGGSMNPARTLAPAVASNVFTGLWIYFLGPVIGTLSGAWVYTYIRFEEAPAAKDTQRLSSFKLRRMQSQLAADEFDTV
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Aquaporin NIP2-2, NOD26-like intrinsic protein 2-2, ZmNIP2-2, ZmNIP2;2.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. NIP (TC 1.A.8.12) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LGT_RHILW
Sequence: MPTAANLLAIMPFPDIDPIAFSIGPLAIHWYGLAYVAGILLGWAYARRLAANESLWPGNASPMTRTQLDDFIVWAALGVVLGGRLGYIFFYDLPAVLRSPVRALEIWNGGMSFHGGLTGTTIAMIIFARRNGIPIWSLFDIVATVVPFGLFFGRIANFINGELWGRLTDVPWAVVFPTGGPFARHPSQLYEAGLEGIVLLLVLAALVYGMRALKSPGFITGVFVCGYALSRIFVEFFREPDAQLGYLLGTNWLTMGMVLSSPMILLGLWAMLRARRQAALQL
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBL_PICSI
Sequence: MSPKTETKASVGFKAGVKDYRLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVPGEESQFIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDVTLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEVIREASKWSPELAAACEIWKEIKFEFEAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CBBR_XANFL
Sequence: MAPHWTLRQLRLVALAAASGSYAKAAQDMGLSPPAVTAQMKALEEDIGVPMFERVDGRLRPTAAGQELLSAQERIARALSEAERAIAALKSPERGSVVVGVVSTAKYFAPMALAAFRRRRPEIELRLIIGNREDIIRGIVSLDFDVAIMGRPPPALEAETRLIGDHPHIVVAPVDHPLFKRRKRITPADLTRESLLVREPGSGTRILMERVFEEAGAPNPPIAMEIGSNETIKQSVMAGLGLAFISAHTVAAEVADGRLRVLEVEGLPVVRQWLAVRARDKRLLPAGQALMDFLEREGASFLPQMPGGEGGRCYLPDHVSGSTPAKAVARDPV
What is the function of this protein?
Transcriptional activator for the cbb operon (cbbLSXFP) for RuBisCO and other Calvin cycle genes.  Binds specifically to two binding sites in the cbbR-cbbL intergenic region.
What are the official names of this protein?
HTH-type transcriptional regulator CbbR, RuBisCO operon transcriptional regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: XKDP_BACSU
Sequence: MTKSVYEFWISQGKDKLRLPVLPDQLSISNTVQNETVKVAKFGDLTFIDEQGAKEISFSSFFPKKYSPIAEYQNFPSPENAITKIEKWMKAKKPVQFLITGTKVNLTCSIEGFSYSEGQQDIGDRSFDIQLKEYKTASPRKIKQKKKTKAKRPSKAAPKTYTVKKGDTLWDIAGRFYGNSTQWRKIWNANKTAMIKRSKRNIRQPGHWIFPGQKLKIPQ
What are the official names of this protein?
Phage-like element PBSX protein XkdP.
Protein: Y1921_STAA9
Sequence: MVRESIPKEGENIKIQSYKHDGKIHRVWSETTILKGTDHVVIGGNDHTLVTESDGRTWITREPAIVYFHSEYWFNVICMFREDGIYYYCNLSSPFVCDEEALKYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDIILRRNVDILQQWIEQKKGPFAPDFIKVWKERYKKIRQY
What are the official names of this protein?
UPF0374 protein SaurJH9_1921.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: RNS1A_RATEX
Sequence: MGLEKSLILFSLLVLVLGWVQPSLGRESSADKFKRQHMDTEGSSKSSPTYCNQMMKRREMTTGSCKPVNTFVHEPLEDVQAICSQGQVTCKNGRNNCHKSSSTLHITDCRLKGSSKYPNCDYTTTDSQKHIIIACDGNPYVPVHFDASV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic alpha-type, RNase 1 gamma.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: CISD2_DROGR
Sequence: MEPISHLVKSSLPNYLSSLPVPDSLGGWFKLSFKDWLALIPPTAVLAGLGYTAYLAFCPAAQCSAKSARCNNHIRKHEAKVVDMIDVEDIAEKAAFCRCWKTKNWPYCDGSHGEHNKLTGDNVGPVVVSKKK
What are the official names of this protein?
CDGSH iron-sulfur domain-containing protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the CISD protein family. CISD2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: ASSY_THENN
Sequence: MKEKVVLAYSGGLDTSVILKWLCEKGFEVIAYVANVGQKDDFEAIKEKALKTGASKVYIEDLRREFVTDYIFTALLGNALYEGRYLLGTAIARPLIAKRQVEIAEKEGAQYVAHGATGKGNDQVRFELTYAALNPNLKVISPWKDPEFLSRFKGRTDLINYAREKGIPVKVSKKRPYSEDENLMHISHEAGKLEDPMYIPDEDVFTWTVSPKEAPDEETLLEIHFEKGVPVKVVNLKDGTEKTDPLELFEYLNEIGAKNGVGRLDMVENRFIGIKSRGVYETPGATILWIAHRDLEGITMDKEVMHLRDMLAPKFSELIYNGFWFSPEMEFLLAAFKKSQENVTGKVIVSVYKGNVMPVARYSPCSLYNPELSSMDVEGGFDATDSKGFINIHALRLKVYRLTKKGYEK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_DESTE
Sequence: DLANFLNCLGARVRGAGTDVIKIEGVDSLGGCLRYAVIPDRIEAGTFMVAAAATRGDVVLENVIPRHLEPLIAKLREAGVEVGEEEDRVRVRASGPLSPIDIKTMPYPGFPTDMQSQMMALLSTVPGTSVIVENIFENRFKVADELKRMGARIKVEGRLAVVEGVERLQGACVRATDLRAGAALVVAGLMAEGETRIDNVQYIDRGYFNLEQKLRMLGARIWRAPYDEKTPAQDNAVRKSALI
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine (By similarity).
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKUD_BACSU
Sequence: MLTYQVKQGDTLNSIAADFRISTAALLQANPSLQAGLTAGQSIVIPGLPDPYTIPYHIAVSIGAKTLTLSLNNRVMKTYPIAVGKILTQTPTGEFYIINRQRNPGGPFGAYWLSLSKQHYGIHGTNNPASIGKAVSKGCIRMHNKDVIELASIVPNGTRVTINR
What is the function of this protein?
Probable enzyme that may play an important role in cell wall biology.
What are the official names of this protein?
Putative L,D-transpeptidase YkuD, Spore protein YkuD.
What is the protein family that this protein belongs to?
Belongs to the YkuD family.
What are the subcellular locations of this protein?
Spore wall. Note=Probably localized either on the surface of the outer spore membrane and/or in the inner spore coat.
Protein: COAD_ECODH
Sequence: MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_CITBB
Sequence: MQLNTIKPAIGSTKNRKRIGRGVGSGHGKTATKGHKGQKARSGGSVKPGFEGGQMPMHRRLPKRGFTPLSKKDYALVNLCQLEVFEAGSVIDAEALLKSGIISGVRDGIKVLATGDITRALTIKAHKFSASAREKITAAGGSIEEI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RLMH_POLSJ
Sequence: MRLTIVAVGQKVPDWAQTAYDDYAKRFPPELKVELKAVKTEPRASKTLENLLAAERARIESVITRGTRVVALDERGTAVTTVALAEKLKAWQLSGDDVAIVIGGPDGLDPAFKQSAHERLRLSDLTLPHAMVRVLLIEQLYRAWSITINHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y913_TREPA
Sequence: MPKHNKLLGAFGEAYAARWLATRGYIIITRNWRRATGEIDIIAQQDDTIVFVEVKTLRCTSYADLAIIVGKRKQKRICETAKHFLASAREYNHMCARFDVIVLRSDPFRRQDVDIVHLPHAFEDLV
What are the official names of this protein?
UPF0102 protein TP_0913.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: EI3G1_DROWI
Sequence: MPGVETIKSSWADEVELDYGGLPPTTETVENGHKYVTEYKYNKDDKKTKVVRTYKISKQVVPKTVAKRRTWTKFGESKNDKPGPNSQTTMVSEEIIMQFLNSKEDEKANDPLLDPSKNIAKCRICNGEHWSVNCPYKGTAMDTNLMEKKAAAAASAAVDAPKSGKYVPPFLKDSQKGGMGMRGRDDTAAIRISNLSESMTEADLEELVKKIGPQSKMYLARDKNTGLCKGFAYVHFKQRKDAAAAIEILNGHGYDHLILSVEWSKPQNN
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G-1, Eukaryotic translation initiation factor 3 RNA-binding subunit 1, eIF-3 RNA-binding subunit 1, Eukaryotic translation initiation factor 3 subunit 4-1.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_SALNS
Sequence: MVSGRVQALLEQLRAQGIRDEQVLNALAAVPREKFIDEAFEHKAWENIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVHHVCSVERIKGLQWQARRRLKQLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMAQLDEGGILVLPVGDEQQFLKRVRRRGGEFIIDTVEAVRFVPLVKGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAP4A_RAT
Sequence: MVSMTFKRSRSDRFYSTRCCGCCHVRTGTIILGTWYMVVNLLMAILLTVEVTHPNSMPAVNIQYEVIGNYYSSERMADNACVLFAVSVLMFIISSMLVYGAISYQVGWLIPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQLPDFPYKDDLLALDSSCLLFIVLVFFVVFIIFKAYLINCVWNCYKYINNRNVPEIAVYPAFEAPPQYVLPTYEMAVKIPEKEPPPPYLPA
What is the function of this protein?
May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment.
What are the official names of this protein?
Lysosomal-associated transmembrane protein 4A.
What is the protein family that this protein belongs to?
Belongs to the LAPTM4/LAPTM5 transporter family.
What are the subcellular locations of this protein?
Endomembrane system; Multi-pass membrane protein. Note=May reside in an intracellular membrane-bound compartment.
Protein: RBFA_STRP7
Sequence: MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGDLSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEYGNKIDEMLRNLDKN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFDQ_ECOLI
Sequence: MSQNLDATAINQIHALISAQGVNEIISKIGADAVALPENFRIHDLEKFNLNRFRFRGALSTASIDDFTRYSKDLADEGTRCFIDADNMRAVSVLNLGTIDEPGHADNTATLKLKKTAPFSALLSVNGERNSQKSLAEWIEDWADYLVGFDANGDAIQATKAAAAIRKITIEANQTADFEDNDFSGKRSLMESVEAKTKDIMPVAFEFKCVPFEGLKERPFKLRLSIITGDRPVLVLRIIQLEAVQEDMANEFRDLLVEKFKDSKVETFIGTFTA
What are the official names of this protein?
Uncharacterized protein YfdQ.
Protein: ACCD6_MYCBO
Sequence: MTIMAPEAVGESLDPRDPLLRLSNFFDDGSVELLHERDRSGVLAAAGTVNGVRTIAFCTDGTVMGGAMGVEGCTHIVNAYDTAIEDQSPIVGIWHSGGARLAEGVRALHAVGQVFEAMIRASGYIPQISVVVGFAAGGAAYGPALTDVVVMAPESRVFVTGPDVVRSVTGEDVDMASLGGPETHHKKSGVCHIVADDELDAYDRGRRLVGLFCQQGHFDRSKAEAGDTDIHALLPESSRRAYDVRPIVTAILDADTPFDEFQANWAPSMVVGLGRLSGRTVGVLANNPLRLGGCLNSESAEKAARFVRLCDAFGIPLVVVVDVPGYLPGVDQEWGGVVRRGAKLLHAFGECTVPRVTLVTRKTYGGAYIAMNSRSLNATKVFAWPDAEVAVMGAKAAVGILHKKKLAAAPEHEREALHDQLAAEHERIAGGVDSALDIGVVDEKIDPAHTRSKLTEALAQAPARRGRHKNIPL
What is the function of this protein?
Component of a biotin-dependent acyl-CoA carboxylase complex.  This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate.  When associated with the alpha3 subunit AccA3, is involved in the carboxylation of acetyl-CoA and propionyl-CoA.
What are the official names of this protein?
Biotin-dependent acetyl-/propionyl-coenzyme A carboxylase beta6 subunit, Acetyl-CoA carboxylase, ACC, Propionyl-CoA carboxylase, PCC.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
Protein: SDHD_LACPL
Sequence: MDTTVMIEEHPQIKELIAKRPIVWQNPDYGKRADLPLTRADIFDAVARWERFAPFLAVAFPETAAMNGIIESPLLPLEQMKPAWEALNHQSLAGQLYLKADSQLPISGSIKSRGGIYEVLKFAEQVAMAHTDLTYMDDYSVLATAKYHELFAQYGVIVASTGNLALSVGIMAATFGFKTTVYMSHDARQWKKDKLRANGVTVEELNTDFSSVIPVARAAAAKDDHTHFVDDEGSRDLFLGYAVAGVRLQHQLKVQGIKMDAAHPVVVYLPAGVGGSPSGVAFGLKMIMGANIYPVFCEPTHVPSVTLGMMTKLNEKIAVQDIGLDGLTAADGLAVSRPSRLAGKVMRTLLLGTATFEDDDLYRYLTKLVDTEDVIVEPSAAAGFTAIAPIMAQFPTLAGKDVTHIVWATGGDMMPESERQLDYELGQKLLTKINNR
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: CHEA_KLEAK
Sequence: MSMDISAFYQTFFDEADELLADMEQHLLELDPQAPDIEPLNAIFRAAHSIKGGAATFGFSVLQETTHLLENLLDGARREEMRLSTEIINLFLETKDIMQEQLDAYKTSQQPDAESFDYICQALRQLALEAQQQDAPAAPPVVAQPAPTAVAGGMRVSLTGLKANEIPLMLEELGNLGEVHDPQQTDNSLEVTLLTTASEEDICAVLCFVLEPEQISFTTPPTTAAKPLPSAEVVPPPVAQPQPAVVEPPKAPRAKASESTSIRVAVEKVDQLINLVGELVITQSMLAQRSGNLDPVTHGDLLNSMSQLERNARDLQESVMSIRMMPMEYVFSRYPRLVRDLAGKLNKQVELTLQGSSTELDKSLIERIIDPLTHLVRNSLDHGIEDPQTRLAAGKSEVGNLILSAEHQGGNICIEVIDDGAGLNREKILAKAAAQGLAVSDSMSDEEVGMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVEIHSRAGKGTSIRILLPLTLAILDGMSVKVNEEVFILPLNAVMESLQPQAEDLHPMAGGERMLQVRGEYLPLVELYRVFDVAGAKTEATQGIVVILQSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQMLNREKLLSAAAA
What is the function of this protein?
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.  CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).
What are the official names of this protein?
Chemotaxis protein CheA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOF_RICPR
Sequence: MLKEEDKIFTNLYGQQSYDLKSSQKRGDWYNTKALIDKGRDFIIDEVKKSGLRGRGGAGFSTGMKWSFMPKNSEKPCYLVVNADESEPGTCKDRDILRFEPHKLIEGCLIASFAIGANTCYIYIRGEFYNEASNMQRALDEAYKEGLIGKNACGSGFDCNIYLHRGAGAYICGEETALLESLEGKKGMPRLKPPFPAGFGLYGCPTTINNVESIAVVPTILRRGASWFAAIGKPNNTGTKVFCISGHVNKPCNIEEVMGVPLKELIEKYAGGVRGGWNNLKAIIPGGASVPLLPKSLCEVEMDFDSLRTVGSGLGTGGIIVMDKSTDIIYAIARLSKFYMHESCGQCTPCREGTGWMWRVMMRLVNGNAKKNEIDTLLNVTKEIEGHTICALGDAAAWPIQGLIRHFRDEIEQRIKSFGIA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit F, NADH dehydrogenase I subunit F, NDH-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.
Protein: RD23B_BOVIN
Sequence: MLVTLKTLQQQTFKIDIDPDETVRALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTALKEYKIDEKNFVVVMVTKPKAVTTPAPATTQQSNSAATTTVSSSTAPAVTQAPAPAPASAPTPTPVSVTPAPTTASSEPAPASAAKQEKPAERPVETPVATTPTSTDSTSGDSSRSNLFEDATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAVEYLLMGIPGDRESQAVVDPPPAASTGAPQSSVAAAAATTTATTTTTSSGGHPLEFLRNQPQFQQMRQIIQQNPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGGGHMNYIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED
What is the function of this protein?
The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex.  The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs.  The orientation of XPC complex binding appears to be crucial for inducing a productive NER.  XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery.  Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation.  Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair.  In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.  XPC:RAD23B contacts DNA both 5' and 3' of a cisplatin lesion with a preference for the 5' side.  XPC:RAD23B induces a bend in DNA upon binding.  XPC:RAD23B stimulates the activity of DNA glycosylases TDG and SMUG1 (By similarity).
What are the official names of this protein?
UV excision repair protein RAD23 homolog B.
What is the protein family that this protein belongs to?
Belongs to the RAD23 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: SIR1_YEAS1
Sequence: MLQINSRLAVIDGWLVDTVKRKPINFRSPEVRLLLPNDDDYKKLSQQNLVDWTRLKKDSNSVLVGVKSMELFKHIKLVLREFFLLEDGRIILKRIRSKSRYKVVKKLTCKCCRLYLPKWGTVYIHPMLKDKEKPLAGVCEFSLDVNPDREYPLIEINVSHQYIIIEGFLLYLNERRLYRWNDNNLRGQVGLTKWAHLRKTYNPVSLDILYSLNSNFYFVKDDLLFQLLGKRVFVKFCKVMENGKCGKAPLWYRVKRTTTAKATHIAYAISNSTAPDSFKSKNNDYRFIVREKPIVENTISNLDYSDIKKQQFTEAEVVKRKISADISQIENVHTQFNSQKEKNNIRVNKVSSEILDQISKFPVSRVTLLLMSAGQDKNYIELVEELARRLEKICIEKTTQSLEEIRDTFQANPEMQARFDKEYYQSIEEYKITLELIKEDLLITLIKQMENMWAAEKKFSTEEEYVSPRFLVADGFLIDLAEEKPINPKDPRLLTLLKDHQRAMIDQMNLVKWNDFKKYQDPIPLKAKTLFKFCKQIKKKFLRGADFKLHTLPTEANLKYEPERMTVLCSCVPILLDDQTVQYLYDDSIIPEFEATSSYATKQSKCGRKMSLQMEPDLLFQEAIRRMRHLTAYDVLRRNYIAAFEELYMGNCND
What is the function of this protein?
Involved in the establishment, but not the maintenance, of heterochromatic silencing at the cryptic mating-type loci HMR and HML.  Is recruited by interacting with the ORC1 subunit of the origin recognition complex (ORC), which binds to HML-I or HMR-E silencers, DNA elements that direct the formation of silent chromatin at the mating-type loci.  Establishes transcriptional silencing by recruiting the three other SIR proteins, SIR2, SIR3, and SIR4, that function directly in silenced chromatin and establish repression.  Also found in centromeric chromatin.  Binds to and helps retain CAC1, a subunit of chromatin assembly factor I (CAF-I) at centromeric loci independent on the other SIR proteins (By similarity).
What are the official names of this protein?
Regulatory protein SIR1, Heterochromatin protein SIR1, Silent information regulator 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Associated primarily with the HMR-E silencer at the HMR locus.
Protein: GTPBA_HUMAN
Sequence: MVHCSCVLFRKYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKISALKGSKGKDCEIPVPVGISVTDENGKIIGELNKENDRILVAQGGLGGKLLTNFLPLKGQKRIIHLDLKLIADVGLVGFPNAGKSSLLSCVSHAKPAIADYAFTTLKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTRQLLFVVDISGFQLSSHTQYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFHELMSQLQNPKDFLHLFEKNMIPERTVEFQHIIPISAVTGEGIEELKNCIRKSLDEQANQENDALHKKQLLNLWISDTMSSTEPPSKHAVTTSKMDII
What is the function of this protein?
May be involved in the ribosome maturation process.  Complements an ObgE(CgtA) function in E. coli ribosome maturation.  Plays a role of GTPase in vitro.  When missing, disorganization of the nucleolar architecture is observed.
What are the official names of this protein?
GTP-binding protein 10, Protein obg homolog 2, ObgH2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome. Note=Found in the dense fibrillar compartment region of the nucleolus. At the onset of mitosis moves to the chromosome surface and remains there until anaphase. Gradually re-assembles into the nucleolus at late anaphase to telophase.