PharMolix/UniProtQA huggingface dataset:
Protein: PHB2_BOVIN
Sequence: MAQNLKDLAGRLPSGPRGMGTALKLLLGAGAVAYGIRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAMELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAARMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK
What is the function of this protein?
In the plasma membrane, is involved in IGFBP6-induced cell migration (By similarity).  Cooperates with CD86 to mediate CD86-signaling in B lymphocytes that regulates the level of IgG1 produced through the activation of distal signaling intermediates.  Upon CD40 engagement, required to activate NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation (By similarity).
What are the official names of this protein?
Prohibitin-2.
What is the protein family that this protein belongs to?
Belongs to the prohibitin family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Cytoplasm. Nucleus. Cell membrane.
Protein: CYB_LASNO
Sequence: MTNIRKSHPLLKIINNSFIDLPAPSNISSWWNFGSLLGICLALQILTGIFLAMHYTSDTATAFNSVTHICRDVNYGWVLRYLHANGASMFFICLYLHVGRGLYYGSYMYKETWNMGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SEPF_GLOVI
Sequence: MSSFWSKVKDFVGFGDPLEYEEDGEEYEQVYREENKREEARRATAGTAAAATPTAAAQASDAAPMGSGPARKRVRAGNVIGMPNSGVNEVLVIEPRSFEEAPQIVQHLRDRKSVILNLTLMDSDQAQRSVDFVAGATFAIDGHQERVGDGIFLFTPSSVMISTEMPSQLRQANQAFGGNFRLNPEAPRRAQG
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: DIR22_ARATH
Sequence: MIQKAVSNSSTSFGSITMTDNALTSDVPVNSTVVGQSQGFYAGAAQRELGFLMAMNFAFKTGKYNGSTITILGRNTVFSKVREMTVVGGSGIFRLARGYVEARTKWFDPKTGDATVEYNCYVLHY
What is the function of this protein?
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.
What are the official names of this protein?
Dirigent protein 22, AtDIR22.
What is the protein family that this protein belongs to?
Belongs to the plant dirigent protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: AZOR_MACCJ
Sequence: MTKVLYITGHPNDETVSNSMAAGKSFIESYKQSNPDHEVVHIDLYDTFIPLIDKEVFDGWGKLQSGKGFEALSETEQQKVARLNELSDEFAAADKYIFVTPMWNLSFPAVVKAYIDAVAVAGKAFKYTAEGAVGLLTDKKALLIQSRGGIYSEGPAADFELGNRYLQTILGFFGVPSVEELVIEGHNQMPEKAEEIKADGVRRAEALGKTF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: ALAXM_METBF
Sequence: MTEALYFLDCYMKEFEATVEKVTDDKFVVLDRTVFYPESGGQPSDTGKLVRESDGAEFNVLYVRKFNGDISHEIDGENVSNGLKAGDKVKGFIDWDRRYRHMRMHTATHVIANVIEKEAGAQITGNQLGLDQSRVDFSLEVFDRDKFAEYEKIANDLIAQKSPVNLYLVSRKEAEEKLSRLTTLAKGFSDEIKEVRIVEIEGVTIEACGGTHVKNTEEIKGVKIIKLQNKGKSNRRMYFTLVD
What is the function of this protein?
Functions in trans to edit the amino acid moiety from incorrectly charged Ser-tRNA(Ala) or Gly-tRNA(Ala).  Has no activity on incorrectly charged Ser-tRNA(Thr), nor on correctly charged Ala-tRNA(Ala) or Ser-tRNA(Ser).
What are the official names of this protein?
Alanyl-tRNA editing protein AlaX-M, AlaX-M, Alanyl-tRNA deacylase AlaX-M.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Editing domain AlaX-M subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_ALCBS
Sequence: MTAVNDFLTPRSIAVNAINQTHAKVVLEPLERGFGHTLGTALRRILISSMPGCAITEVEIDGVQHEYSSIEGVQEDVINILLNLKGVALKMEDSEETTLELVKKGPGVVTANDIQRDHSVEIVNPDHLICTITGDTELRVKLKVQKGRGYVAADSRQSEDDETRGIGRLQLDASYSPVRRVAYVVEAARVEQRTDLDKLVIDLETDGTIEPEEAIRRAATILQQQIAVFVDLEQDAKPEPKQEREEIDPILLRPVDDLELTVRSANCLKAENIYYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASKGLSLGMRLENWPPVSLRDDDRLNAKLR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: CDKC1_ARATH
Sequence: MAMASFGQLNLEEPPPIWGSRSVDCFEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHHENVIQLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGNLTNRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLHAKPILPGKNEQEQLNKIFELCGSPDEKLWPGVSKMPWFNNFKPARPLKRRVREFFRHFDRHALELLEKMLVLDPAQRISAKDALDAEYFWTDPLPCDPKSLPTYESSHEFQTKKKRQQQRQNEEAAKRQKLQHPPLQHSRLPPLQHGGQSHAAPHWPAGPNHPTNNAPPQVPAGPSHNFYGKPRGPPGPNRYPPSGNQSGGYNQSRGGYSSGSYPPQGRGAPYVAGPRGPSGGPYGVGPPNYTQGGQYGGSGSSGRGQNQRNQQYGWQQ
What are the official names of this protein?
Cyclin-dependent kinase C-1, CDKC;1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: SC11A_HUMAN
Sequence: MLSLDFLDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:34388369).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (PubMed:34388369).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11A, Endopeptidase SP18, Microsomal signal peptidase 18 kDa subunit, SPase 18 kDa subunit, SEC11 homolog A, SEC11-like protein 1, SPC18.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: PANB_GRAFK
Sequence: MSVAKKEYKRITVKSLVDMKSNGEKISMLTAYDFTMAQIVDGAGIDVILVGDSASNVMAGHETTLPITLDQMIYHATSVVRAITRSLVVVDLPFGSYQSDPKEALRSAIRIMKESGGHAVKLEGGKEVKESIKRIIHAGIPVMGHLGLTPQSIYKFGTYTVRAKEEQEAEKLKSDAKLLEKMGCFAIVLEKVPAELAKEVAESITIPVIGIGAGNGVDGQVLVVHDMLGMTHEFNPRFLRRYADLHGEMTKAFQNYRDDVKSRKFPSDDEQY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_EXISA
Sequence: MKCIVGLGNPGKKFEMTRHNVGFLAIDRLAEKHGISLNEAKFNALMGTGRINGERVVLVKPLTYMNLSGEAVRPILDYYKIEIDDLLVIYDDLDMVPGKLRFRPKGSAGGHNGIKSLIQHLGTAEFKRLKLGIGRPPHPIKVVDWVLMNYRKDELPELNETLDNAVTAATDFVDTDWLALMNRYN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_MYCSK
Sequence: MLPARYRMTRSTEFSTTVSKGVRSAQPDLVLHMANVLDDPSGPRVGLVVAKSVGNAVVRHRVSRRLRHSVHPMLDELQPGHRLVIRALPGAASATSARLHQELSAALRRARPRVEASA
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: GATA_RICB8
Sequence: MTELNKLSVADSLKGLKNKEFTSKELVNAHIKQIEKHKNLNAYVTETFDLALKQAEEADQSYAKNHSRTLEGIPFAAKDLFCTKGIRTTACSNILREFIPNYESGVTQNIFNKGGVMLGKTNMDEFAMGSANITSCFGNVISPWKALDDGADLVPGGSSGGSAAAVSGFMATAALGSDTGGSVRQPASFTGLVGFKPTYGRCSRYGMVSFASSLDQAGIFTRSVLDSSIMLEAMIGFDERDSTSIKMEVPQLQPAIGSSIKGMKIGVPLSLGEGGIIEPDIMKMWHSTIELLKDAGAEIIDISLPHAKYGVAVYYVIAPAEASSNLSRYDGVRYGLRVEKENMSLDEMYEITRSSGFGDEVKRRIMIGTYVLSSSFMDAYYLKAQKVRRLVADDFNNAFAKVDAILLPSAPTEAFRIGEKQNDPTIMYLNDLFTIPASLAGLPCVSVPAGLSNRGLPLGMQVICKQLDEYNVLRVASAIEAGVKHIKFEPVGF
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: BAT_HALSA
Sequence: MTSVQNTESETAAGATTIGVLFAGSDPETGPAACDLDEDGRFDVTQIRDFVAARDRVDDPDIDCVVAVHEPDGFDGVAFLEAVRQTHAEFPVVVVPTAVDEDVARRAVDADATGLVPAVSEDATAAIADRIEQSAPAHSEDTETRMPISDLTVESERRLKEQALDEAPIGITISDATDPEEPIIYINDSFEDITGYSPDEVVGANHRFLQGPKTNEDRVAEFWTAITEDHDTQVVLRNYRRDGSLFWNQVDISPIYDEDGTVSHYVGFQMDVSERMAAQQELQGERQSLDRLLDRVNGLMNDVTSALVRAADREEIETRITDRIGTGGEYAGAWFGRYDATEDTITVAEAAGDCEGCDGDVFDLASAGEAVALLQDVVEQREALVSTDADGVSGTADGDACVLVPVTYRSTTYGVLAVSTAEHRIDDREQVLLRSLGRTTGASINDALTRRTIATDTVLNIGVELSDTALFLVELAGATDTTFEQEATIADSQTQGVLMLVTTPHDDPQAVVDTALGYDAVQDAEVIVSTDDESVVQFDLSSSPLVDVLSECGSRVIRMHADRTTLELDVRVGTEGAARRVLSTLRDKYADVELVAYHEDDPEQTPHGFREELRNDLTDRQLTALQKAYVSGYFEWPRRAEGKQLAESMDIVPSTYHQHLQAAKQKLVGAFFEE
What is the function of this protein?
Involved in activating bop (bacterioopsin) and brp gene expression at low-oxygen tension, which naturally occurs in stationary phase.
What are the official names of this protein?
Bacterioopsin transcriptional activator.
Protein: RPOZ_CYACA
Sequence: MVDKRNHYFLLHKIEELLELSASKYKTTMEIANYAKKTKNRNANKSNIKPVILAILEISGELKLNDINKLTN
What is the function of this protein?
May be involved in RNA polymerase activity.
What are the official names of this protein?
Putative DNA-directed RNA polymerase subunit omega, PEP, Plastid-encoded RNA polymerase omega subunit, RNA polymerase omega subunit.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MEND_KLEP7
Sequence: MSVSAFNRRWAAVILEALTRHGVQHICIAPGSRSTPLTLAAAENRAFIHHTHFDERGLGHLALGLAKASRQPVAVIVTSGTATANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPAQTISLPRPSQDIPARWLVSTIDQALGALHAGGVHINCPFAEPLYGDMDETGVEWQQQLGNWWQSDKPWLRQALQLESEKQRDWFFWRQKRGVVVAGRMSAAEGKKVAEWAQTLGWPLIGDVLSQTGQPLPCADLWLGNGKAVSELAQAQIVVQLGSSLTGKRVLQWQATCEPDEYWLVDNLPGRLDPAQHCGRRLLSSVERWLELHPAEKRQPWATVIPQLAGQAWQAAVASNEPFGEAQLAQRIRRYLPEQGQLFVGNSLVVRLIDALAQLPAGYPVYSNRGASGIDGLIATAAGVQRASARPTLAIVGDLSALYDLNSLALLRQASAPLVLIVVNNNGGQIFSMLPTPQDERRQFYLMPQDVDFSHAAVMFGLAYHRPDDWPSLDEALAGAWRRAGATVIELAVNETDGAQTLQQLLAQVSRL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: ACCD_METRJ
Sequence: MVEPMNWISEVVRPRIKTLFKRETPENLWVKCPDTGQMVFHKEVEANHWVIPGSEHHLKMGAQARLKMMFDEGTWIDVALPEVAPDPLKFRDEKRYVDRLKEARAKTGLQDAFKIGFGRVGGLPMTLAAQEFGFMAGSLGMAAGEAFVRGAETALEKRTPYVLFAASGGARMQEGILSLMQMPRTTVAVRRLNAARLPYIVVLTNPTTGGVTASYAMLGDVHLAEPGALICFAGPRVIEQTIREKLPDGFQRAEYLREHGMVDQVVHRHQLKETIARLCSLLTNVSQAGAPAAASEAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLTC_STAEQ
Sequence: MEFREQVLDLLAEVAENNIVKENPDVEIFEEGIIDSFQTVGLLLEIQNKLDIEVSIMDFDRDEWATPNKIVEALEELR
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_BPH75
Sequence: MDFNPSEVASQVTNYIQAIAAAGVGVLALAIGLSAAWKYAKRFLKG
What is the function of this protein?
Self assembles to form a helical capsid wrapping up the viral genomic DNA.  The capsid displays a filamentous structure with a length of 760-1950 nm and a width of 6-8 nm.  The virion assembly and budding take place at the host inner membrane (By similarity).
What are the official names of this protein?
Capsid protein G8P, Coat protein B, Gene 8 protein, G8P, Major coat protein.
What is the protein family that this protein belongs to?
Belongs to the inovirus capsid protein family.
What are the subcellular locations of this protein?
Virion. Host membrane; Single-pass membrane protein. Note=prior to assembly, the major capsid protein is found associated with the bacterial host inner membrane.
Protein: FAS_BOVIN
Sequence: MEEVVITGMSGKLPESENLEEFWANLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRFDASFFGVHPKQAHNMDPQLRLLLEVTYEAIVDAGINPASIRGTNTGVWVGVSGSEASEALSRDPETLVGYSMVGCQRAMLANRLSFFFDFKGPSITLDTACSSSLLALQRAYQAIQRGECAMAIVGGVNIRLKPNTSVQFMKLGMLSPEGTCKFFDASGNGYCRAKAVMAILLTKKSLARRVYATILNAGTNTDGCKEKGVTFPSGEAQEQLISSLYKPAGLDPETLEYVEAHGTGTKVGDPQELNGIVQALCGTRQSPLRIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHNPNPKIPALQDGRLQVVDRPLPVLGGNVGINSFGFGGSNVHVILQPNSQPLPPPAPHAALPRLLRASGRTLEGVQGLLELGLQHSQNLAFVSMLNDIATPSPAAMPFRGYAVLGSQGGSQKVQQVLAGKRPLWFICSGMGTQWRGMGLSLMRLSRFRDSILRSDEAVKPLGLQVSQLLLSTDEAIFDDMVISFVSLTAIQIALIDLLTSMGLQPDGIIGHSLGEVACGYADGCISQEEAILSAYWRGQCIKEANIPPGAMAAVGLTWEECKQRCPPGIVPACHNCIDTVTISGPQASMLEFVQQLKQEGVFAKEVRTGGMAFHSYFMDAIAPMLLQQLKKVIREPQPRSPRWLSTSIPETQWQESLARTFSAEYNVNNLVSPVLFQEALWRVPEDAVVLEIAPHALLQAVLKRGLKSSCTIIPLMKKDHRDNLEFFLSNVGQLYLTGIDVNPNGLFPPVEFPAPRGTPLISPHIKWDHSQTWDVPTAEDFPSGSSSSSATIYKIDINPESPDHYLVDHCIDGRIIFPGTGYLCLVWKTLARALDQNMEHTPVVFEDVTLHQAVILPKTGIVLLKVRLLEASCTFEVSENGNLIASGKVYQWEDPNPKLFDNRYGPDPATPVDPTTAIHLSRGDVYKELQLQGFNYGPYFQGILEASSEGNTGQLLWKDNWVTFMDTMLQMSILAPSKRSLRLPTRITAIYIHPATHQQKLYTLQDKTQVADVVINRCLDTTVAGGIYISRIHTSVAPRHQQEQLVPILEKFCFTPHVETGCLAGNLALQEELQLCVGLAQALQTRVAQQGIKMVVPGLDGAQAPQEAPQQGLPRLLATACQLQLNGNLQMEMGQILAQERALLCDDPLLSGLLNSPALKACVTLALENMTSLKMKVVLAGDGQLYSRIPTLLNTQPLLELDYTATDRHPQALEAAQAKLQQLDITQGQWDPSDPAPSNLGGANLVVCNYALASLGDPATAVGNMVAALKEGGFLLLHTLLRGHPLGETVTFLTCPEPQQGQRHLLSQDEWERLFAGASLHLVALKKSFYGSVLFLCRRLAPLDSPIFLPVEDTSFQWVDSLKNILADSSSRAVWLMAVGCTTSGVVGLVNCLRKEPDGHRIRCVLVSNLNSTSPIPETDPKSLELQKVLQSDLVMNVYRDGAWGAFRHFPLEQDKPEEQTEHAFINVLTRGDLSSIRWVCSPLRHSQPTAPGFQLCTIYYASLNFKRNHAGHGQAVPRRHPRNWASRNCLLGMEFSGRDASGKRVMGLVPAEGLATSTLVPQSFLWDVPSNWTLEEAASVPVVYSTAYYALMVRGRMQPGETVLIHSGSGGVGQAAIAIALSLGCRVFPLVGSAEKRAYLQSRFPQLNETSFANSRDTSFEQHVLWHTAGKGADLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSKNHPLGMAIFLKNVTFHGILLDSLFEENNTMWQEVSTLLKAGIRKGVVQPLKRTVFPRTQAEDAFRYMAQGKHIGKVVIQVREEEQEAVLHGTKPTQMVALCKTFCPAHKSYIITGGLGGFGLELAHWLVERGAQKLVLTSRSGIRTGYQARQVHEWRRQGVQVLVSTSDVSTLDGTRSLITEAAQLGPVGGIFNLAVVLRDAMLDNQTPEFFQDVNKPKYNGTLNLDRVTREACPELDYFEVFSSVSCGRGNAGQTNYGFANSTMERICEKRRHDGLPGLAVQWGAIADVGLLMELKGTKDKAIGGTLPQRITSCMEVLDLFLNQPHPVLSSFVLAEKATSRGPSGSHQDLVKAVTHILGIRDLATVNLDSSLSDLGLDSLMGVEVRQMLEREHNLLLSMREIRQLTIHKLQEISAQAGTADELTDSTPKFGSPAQSHTQLNLSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSTTVFHSLATKLSIPTYGLQCTGAAPLDSIQSLATYYIECIRQVQPEGNYRIAGYSYGACVAFEMCSQLQAQQNAGPTNNSLFLFDGSHTFVMAYTQSYRAKLNPGCEAEAEAEAMCFFMQQFTEAEHSRVLEALLPLGDLEARVAATVELIVQSHAGLDRHALSFAARSFYHKLRAAEEYTPRATYHGNVTLLRAKMGSAYQEGLGADYNLSQVCDGKVSVHIIEGDHRTLLEGSGLESILSIIHSSLAEPRVSVREG
What is the function of this protein?
Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH.  This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.
What are the official names of this protein?
Fatty acid synthase.
What are the subcellular locations of this protein?
Cytoplasm. Melanosome.
Protein: ISCS_NEIMF
Sequence: MTVKTPVYLDYAATTPVDKRVAEKMIPYLTETFGNPASNSHAFGWEAEEAVEKARADIAALINADPKEIVFTSGATESDNLAIKGAANFYKTKGKHLITVKTEHKAVLDTMRELERQGFEVTYLGVQENGLIDLEELKAAIRDDTILISVMWANNEIGVVQDIPAIGEICRERKIVFHVDAAQACGKVPVDVEAAKIDLLSMSAHKVYGPKGIGALYVRRKPRVRLEAQMHGGGHERGFRSGTLPTHQIVGMGEAFRIAKEELEQDMAHYRKLRDIFLKGIEGIEEVYINGDLEHRAPNNLNVSFNFVEGESLIMAVKELAVSSGSACTSASLEPSYVLRALGRNDELAHSSLRITFGRMTTEEEVQFAAELIKSKIGKLRELSPLWEMFKDGIDLNSIEWAAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_NANEQ
Sequence: MKPISASIVRALPVGAYLNVADNSGAKVVKLIAVKGYKGRKRRLAKAGIADLVIVSVRDGKPDMIGQIFKAVVVRMKKEWRRRDGTRIKFEDNAVALLKDDYGTPKGTIIKTPIAKEVAERWPDLAKIARIIV
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NCAP_WWAVU
Sequence: MSDQSVPSFRWTQSLRRGLSAWTTSVKADVLNDTRALLSGLDFAKVASVQRMMRRVKRDDSDLVGLRDLNKEVDSLMIMKSNQKNMFLKVGSLSKDELMELSSDLEKLKQKVQRTERVGNGTGQYQGNLSNTQLTRRSEILQLVGIQRAGLAPTGGVVKIWDIKDPSLLVNQFGSVPAVTISCMTEQGGESLNDVVQGLTDLGLLYTAKYPNLNDLKALTTKHPSLNIITQEESQINISGYNLSLSAAVKAGACLIDGGNMLETIKIEESTFTTVIKTLLEVKNKEKMFVSPTPGQRNPYENVLYKLCLSGDGWPYIASRSQIKGRAWDNTVVEFDTATVKEPIPIRNGGAPLLTTLKPEIENQVKRSVESLLINDTTWIDIEGPPNDPVEFAIYQPESQRYIHCYRRPNDIKSFKDQSKYCHGILLKDVENARPGLISSIIRSLPKSMVFTAQGADDIRKLFDMHGRQDLKIVDVKLSAEESRIFEDLVWKRFEHLCDKHKGIVIKSKKKGSTPATTNAHCALLDGVMFSAVISGSVSNEKPKRMLPIDLLFREPETTVVL
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC).  Serves as template for viral transcription and replication.  The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses.  Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.  Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RSMH_STRS4
Sequence: MTKEFNHTTVLLHETVDMLDIKPNGIYVDATLGGAGHSEYLLSQLTDGGHLYAFDQDQTAIDHAHIRLASYIEKGQVTFIRDNFRNLKTRLAELGVTEIDGICYDLGVSSPQLDERERGFSYKQDAPLDMRMNREGHLTAYDVVNNYDYHDLVRIFFKYGEDKFSKQIARKIEQARAVKPIETTTELAELIKSAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQQAIDLLALDGRISVITFHSLEDRLTKQLFKEASTIDVPKGLPFIPDDLKAPLELVNRKPILPSQEELEANNRAHSAKLRVAKKVHK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.