PharMolix/UniProtQA huggingface dataset:
Protein: COX3_PYLLI
Sequence: MKSTAKMIQRHPFHLVDPSPWPLVAALGGLSLTFGGVLFMHNYEGGGELLCLGFFTILYVMFTWWRDVIREALFEGQHTLAVQQGLRMGMILFIVSEIMFFFAFFWAFFTSSISPVFNIGGVWPPTDVVAISPWGLPFLNTILLLSSGASVTWAHHAIVGGLKKEAMQGLSVTLAFAIAFTAMQGFEYSGAPFGMSDGVYGSVFYMATGFHGFHVIIGTIFLFICTIRLYLSHFSCQHHFGFEAAAWYWHFVDVVWLFLFLTIYWWGFNITV
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL38_LYSTE
Sequence: MPREIKEIKDFLVTARRKDAKSVKIKKNAENVKFKVRCSRFLYTLVITDKEKAEKLKQSLPPGLQVKEVKKTNEKL
What are the official names of this protein?
60S ribosomal protein L38.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL38 family.
Protein: SIRK_ARATH
Sequence: MAMLKSLSSILFTSFALLFFLVHAQDQSGFISIDCGIPDDSSYNDETTGIKYVSDSAFVDSGTTKRIAAQFQSSGFDRHLLNVRSFPQSKRSCYDVPTPRGKGFKYLIRTRFMYGNYDDLGRVPEFDLYLGVNFWDSVKLDDATTILNKEIITIPLLDNVQVCVVDKNAGTPFLSVLEIRLLLNTTYETPYDALTLLRRLDYSKTGKLPSRYKDDIYDRIWTPRIVSSEYKILNTSLTVDQFLNNGYQPASTVMSTAETARNESLYLTLSFRPPDPNAKFYVYMHFAEIEVLKSNQTREFSIWLNEDVISPSFKLRYLLTDTFVTPDPVSGITINFSLLQPPGEFVLPPIINALEVYQVNEFLQIPTHPQDVDAMRKIKATYRVKKNWQGDPCVPVDYSWEGIDCIQSDNTTNPRVVSLNISFSELRGQIDPAFSNLTSIRKLDLSGNTLTGEIPAFLANLPNLTELNVEGNKLTGIVPQRLHERSKNGSLSLRFGRNPDLCLSDSCSNTKKKNKNGYIIPLVVVGIIVVLLTALALFRRFKKKQQRGTLGERNGPLKTAKRYFKYSEVVNITNNFERVIGKGGFGKVYHGVINGEQVAVKVLSEESAQGYKEFRAEVDLLMRVHHTNLTSLVGYCNEINHMVLIYEYMANENLGDYLAGKRSFILSWEERLKISLDAAQGLEYLHNGCKPPIVHRDVKPTNILLNEKLQAKMADFGLSRSFSVEGSGQISTVVAGSIGYLDPEYYSTRQMNEKSDVYSLGVVLLEVITGQPAIASSKTEKVHISDHVRSILANGDIRGIVDQRLRERYDVGSAWKMSEIALACTEHTSAQRPTMSQVVMELKQIVYGIVTDQENYDDSTKMLTVNLDTEMVPRAR
What is the function of this protein?
Involved in innate immune response of plants.
What are the official names of this protein?
Senescence-induced receptor-like serine/threonine-protein kinase, FLG22-induced receptor-like kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CH601_THEVL
Sequence: MAKRIIYNENARRALEKGMDILAESVAVTLGPKGRNVVLEKKFGAPQIVNDGVTIAKEIELEDHIENTGVALIRQAASKTNDAAGDGTTTATVLAHAMVKEGLRNVAAGANPIALKRGIDKATQFLVEKIAEHARPVEDSKAIAQVAAISAGNDEEVGRMIADAMDKVGKEGVISLEEAKSMTTELEVTEGMRFDKGYISPYFATDTERMEAVLDEPFVLVTDKKITLVQDLVPILEQVARAGKPLVIIAEDIEKEALATLVVNRLRGVLNVAAVKAPGFGDRSKAMLEDIAVLTAGQVIAEDAGLKLENAKLDMLGKARRITITKDHTTIVAEGNEKAVKARCEQIRRQIEETDSSYDKEKLQERLAKLAGGVAVIKVGAATETEMKDRKLRLEDAINATKAAVEEGIVPGGGTTLVHLAPELSNWAAEHLTGEELIGANIVERALSAPLRRIAENAGQNGAIIVERVKEKPFDVGYDAAKDEYVNMFDAGIVDPAKVTRSALQNAASIAGMVLTTECIIVDKPEPKENNPAGSGAGMGGDFDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_SODGM
Sequence: MRTSQYLLSTLKEVPADAEVVSHQLMLRAGMIRKLASGLYSWLPTGLRVLRKVENIVREEMDNAGAIEVSMPVVQPADLWQESGRWVQYGPELLRFTDRGARAFVLGPTHEEVITDLIRNEVSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFVMKDAYSFHTSQASLQATYDAMYQAYSAIFTRMGLEFRAVQADTGSIGGSASHEFQVLAGSGEDDIVFSTASDYAANIELAEAVAPAAARAAPGEDMRLVNTPDARTIAELVAQFSLPVEKTVKTLLVRAREDAGHPLVALMVRGDHHLNDVKAEKLPQVAAPLTFASEEEIRLAVGAGPGSLGPVNLPLPLVIDRSVAVMSDFAAGANAEGKHFFGINWERDLPLPQVADLRKVVEGDISPDGNGTLQIKRGIEVGHIFQLGTKYSEAMKATVQGEDGRNQTLTMGCYGIGITRVVVAAIEQNHDDRGILWPETLAPFNVAILPMNMHKSFRVKEVAEDLYQQLQARGIDVLLDDRKERPGVMFADMELIGVPHQLVIGDRNLDTEEIEYKNRRSGEKRMIKLSAIVDFLVSEIATAK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_SALTI
Sequence: MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGGSIRPLLTSAGINAGQLRTAIDQALSRLPQVEGTGGDVQPSSELVRVLNLCDKLAQKRGDNFISSELFVLAALESRGTLTDLLKSAGATTANITQAIEQMRGGESVNDQGAEDQRQALKKYTVDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELDDKERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPELEKQLEAATQSEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMLEGEREKLLRMEQELHSRVIGQNEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDDAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELDYGRMKEMVLGVVSQNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLQRLYKRLEERGYEIHISDEALKLLSANGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEANDDRIVAVQ
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EI3G2_DROPS
Sequence: MKPMKTSWADEVEADYVDGLPPTKEYTQGNLKFVAEYKYNEDGKKVKVVRTYKIQKQTVPKVVARRRNWSKFGDSRLDKPGPCSQTTMVAEEVHMVFISSKELEQAQAQEPQMEPGKNIARCRICNGEHWSVNCPYKGTSMDSKTLMESKATAAAAAAVSDASKTGKYVSPFLKEGGCAIGGGIGAKPWVRERSAVRISNLSESMTEADLEELVKKIGPHTKLYLAREKNTGLCKGFAYVHFKFRQDAAAAIEILNGHGYDHLILCVEWSKPQP
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G-2, Eukaryotic translation initiation factor 3 RNA-binding subunit 2, eIF-3 RNA-binding subunit 2, Eukaryotic translation initiation factor 3 subunit 4-2.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYS1_YARLI
Sequence: MTAPVKLHLRAETKPLEHRSALTPTTTRKLLDAGFEVFVEKSPLRIFDDQEFVDVGATLVEEGSWVSAPEDRMIIGLKELPEESFPLSHEHIQFAHCYKDQGGWKDVLSRFPAGNGTLYDLEFLEDDNGRRVAAFGFHAGFAGAAIGVETWAFQQTHPDSENLPGVSAYPNETELVDKIKKDLAAAVEKGSKLPTVLVIGALGRCGSGAIDLARKVGIPEENIIRWDMNETKKGGPFQEIADADIFINCIYLSQPIPPFINYDLLNKETRKLSVIVDVSADTTNPHNPVPVYTIATTFDHPTVPVETTAGPKLSVCSIDHLPSLLPREASEAFSEALLPSLLQLPQRDTAPVWTRAKALFDKHVLRIGE
What is the function of this protein?
Catalyzes the NAD(+)-dependent cleavage of saccharopine to L-lysine and 2-oxoglutarate, the final step in the alpha-aminoadipate (AAA) pathway for lysin biosynthesis.
What are the official names of this protein?
Saccharopine dehydrogenase [NAD(+), L-lysine-forming], SDH, Lysine--2-oxoglutarate reductase.
What is the protein family that this protein belongs to?
Belongs to the AlaDH/PNT family.
Protein: MURB_NOCFA
Sequence: MTGHATVWGVRISRVVPGRAVTGDEVRELLSGTGATVREAVRLAELTTLRVGGPAVLAECGTTEALVATVRALDAAGVPVLLLAGGSNLLVGDDGFDGVVVRVATSGVELGADGVLAEAGADWDAVVAATVAAGLGGLECLSGIPGSAGATPVQNVGAYGVEVAELLRRVRLLDRATGEIRWAGPGELGFGYRTSVLKHSDAAVVLAVEFALRPDGSSAPLRYRELAAALAADEGESRPAAAVREAVLRLRASKGMVLDPADHDTWSAGSFFTNPVVPADRIEQVRAAIHAHVGEVTIPTYPAADGVKLSAGWLIERAGFGKGWPGAEAPARLSTKHTLALTNRGTARAADVVALARTVRDGVAERFGIRLEPEPVTVGVRL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_ACIB5
Sequence: MIENPIKRRPTRKIRVGSVYVGGDAPISVQSMTNTETCDVDATVAQIERCVDAGADIMRVSVPSMEAAEAFGAIRKRVSVPLVADIHFDHRIALAVADYGADCLRINPGNIGSDQKVREVVAAARHHGISMRIGVNAGSLEKDLQKKYGEPTGQALLESALRHIDILDRLDFHEFKVSVKASNVFLTMDAYRLLSQQIDNPLHLGVTEAGIYRTGTVKSAIALGGLLMEGIGDTMRISLAAEPEDEIKIGFDILKSLGLRSNGINFIACPSCSRQEFNVIQVMQALEERLEDIRTPMDVSVIGCKVNGPGEAKEADIGVVGAAPRSLVYRNGEKSHLIDTNQLVDEIETMVRQRVQELEEAKSKEIIRSSS
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: NSP1_ROTHP
Sequence: MATFKDACYHYKRINKLNHTVLKLGVNDTWRSSPPTKYKGWCLDCCQHTDLTYCRGCTMYHVCQWCSQYGRCFLDNEPHLLRMRTFKNEVTKDDLKNLIDMYEILFPMNQKIVCRFINNTRQHKCRNECMTQWYNHLLLPITLQSMSIELDGDVYYVFGYYDNMNSINQTPFSFTNLVDIYDKLLLDDVNFARMSFLPASLQQEYALRYFSKSRFISEQRKCVNDSHFSINVLENLHNPSFKVQITRNCSELSFDWNEACKLVKNVSAYFDMLKTSHIEFYSVSTRCRIFTQCKLKMASKLIKPNYITSNHKTLATEVHNCKWCSVNNSYTVWNDFRIKKIYDNIFNFLRALVKSNVNIGHCSSQEKIYEYVEDVLNVCDDERWKTSIMEIFNCLEPVELDDVKYVLFNHEINWDVINVLVHSIGKVPQILTLENVITIMQSIIYEWFDIRYMRNTPMVTFTIDKLRRLHTGLKTVEYDSGISDIE
What is the function of this protein?
Plays a role in the inhibition of host innate immunity by inducing the degradation of key host factors required to activate interferon production such as IRF3, IRF5 or IRF7.  Associates with components of cullin RING ligases (CRLs) including CUL1 or CUL3, which are essential multisubunit ubiquitination complexes, to modulate their activities.  Recognizes the host NF-kappa-B regulator BTRC through the presence of a DSGXS motif in the C-terminal substrate recognition domain.
What are the official names of this protein?
Non-structural protein 1, NSP1, NCVP2, Non-structural RNA-binding protein 53, NS53.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP1 family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton.
Protein: GMHA_FUSNN
Sequence: MNLISSYKTEFELLRKFIEEEEERKETEKVAQKLANIFTKGKKVLICGNGGSNCDAMHFIEEFTGRFRKERRALPAISISDPSHITCVANDYGFEYIFSKGVEAYGQEGDMFIGISTSGNSPNVIKAVEQAKAQGLVTVGLLGKDGGKLKGMCDYEFIIPGKTSDRVQEIHMMILHIIIEGVERIMFPENYVEE
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_XANCP
Sequence: MTASPSKLAQLRDLSVVVADTGDYDAIKRLKPVDCTTNPTLVKKALDLPVYADLIERELAWGRAHGGEDRNSTINEVADRLTVGVGTMLSELVPGRVSTEVDADLAHDTQATIAKARKFIAMYAERGVSKDKILIKIAATWEGIEAARQLQQEGIDCNLTLIFNRSQALACAEAGVFLISPFVGRILDFFVAKGQTPASIDEDPGVVFVRGVYDEFKRRGSSTVVMGASFRSTAQIEALAGCDRLTISPDLLEKLDADHGDLPRKLSPLNADNAAITPINSDSFATDLAADDMATEKLASGIDTFAKDLEALRKTIADKLAG
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_STAHJ
Sequence: MKCPKCSSTHSRVVDSRHADDANAIRRRRECENCGTRFTTFEHIEVSPLIVVKKDGTREQFLREKILNGLVRSCEKRPVRYQQLEDITNKVEWQLRDSGQTEISSRDIGEHVMNLLMHVDQVSYVRFASVYKEFKDVDQLLASMQGILNDNKRSDL
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: SSPC_STAAR
Sequence: MYQLQFINLVYDTTKLTHLEQTNINLFIGNWSNHQLQKSICIRHGDDTSHNQYHILFIDTAHQRIKFSSFDNEEIIYILDYDDTQHILMQTSSKQGIGTSRPIVYERLV
What is the function of this protein?
Specifically inhibits the cysteine protease staphopain B (SspB) by blocking the active site of the enzyme.  Probably required to protect cytoplasmic proteins from being degraded by prematurely activated/folded prostaphopain B.  Also involved in growth capacity, viability and bacterial morphology (By similarity).
What are the official names of this protein?
Staphostatin B, Staphylococcal cysteine protease B inhibitor.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I57 (SspC) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPA_ECOSE
Sequence: MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDLLVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSDSEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVLTPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKLSAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: RS14Z_STRT1
Sequence: MAKKSLIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFKLCRVCFRELAHKGQIPGVTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: DCUP_PROMS
Sequence: MGQDLPLLLSAALGKKVNRPPVWMMRQAGRYMKIYRDLRERYPSFRERSENPELSYEISMQPFHAFKPDGVILFSDILTPLPGMGINFEIIESKGPIIEDPIRTLNQVENLRELNPSESLSFVGQVLSSLKKDVNNEATILGFVGAPWTLAAYVVEGKSSKNYSLIKSMAFNEPDLLHKLLDHFAKSIGEYLKYQIKSGAQVVQIFDSWAGQLSPQDYDMFAGPYQKKVVEIVKAEYPETPIILYISGSAGVLERMAKTGVDIISLDWTVDIEEACKRIPRGIGIQGNVDPGILFGNKKSIKERIDDTFNKIKDRKYILNLGHGILPGTPEENAQTFFEHGKKLTY
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSUA_PSEAE
Sequence: MRLDRFLANLPELSRRDAQMLIAGGHLRVDGQVVRDGTHEVRVFSRVELDERLLQAGKPARYYMLHKPMGCVSATRDPQHPTVLDLFPEDLRDDLHIGGRLDYNTTGLMLLTNDGQWSRRLTLPGSRRDKVYYVETEAPIDQRYVDAFAAGLHFRFEDLVTLPAQLEPIGPRCARLTLHEGRYHQVKRMFGHFDNKVLRLHRERMGDICLDPQLPPGAWRPLNAEEICSV
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.
What are the official names of this protein?
Ribosomal small subunit pseudouridine synthase A, 16S pseudouridylate 516 synthase, 16S rRNA pseudouridine(516) synthase, rRNA pseudouridylate synthase A, rRNA-uridine isomerase A.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: DPOL_PYRAB
Sequence: MIIDADYITEDGKPIIRIFKKEKGEFKVEYDRTFRPYIYALLKDDSAIDEVKKITAERHGKIVRITEVEKVQKKFLGRPIEVWKLYLEHPQDVPAIREKIREHPAVVDIFEYDIPFAKRYLIDKGLTPMEGNEELTFLAVDIETLYHEGEEFGKGPIIMISYADEEGAKVITWKSIDLPYVEVVSSEREMIKRLVKVIREKDPDVIITYNGDNFDFPYLLKRAEKLGIKLPLGRDNSEPKMQRMGDSLAVEIKGRIHFDLFPVIRRTINLPTYTLEAVYEAIFGKSKEKVYAHEIAEAWETGKGLERVAKYSMEDAKVTFELGKEFFPMEAQLARLVGQPVWDVSRSSTGNLVEWFLLRKAYERNELAPNKPDEREYERRLRESYEGGYVKEPEKGLWEGIVSLDFRSLYPSIIITHNVSPDTLNRENCKEYDVAPQVGHRFCKDFPGFIPSLLGNLLEERQKIKKRMKESKDPVEKKLLDYRQRAIKILANSYYGYYGYAKARWYCKECAESVTAWGRQYIDLVRRELESRGFKVLYIDTDGLYATIPGAKHEEIKEKALKFVEYINSKLPGLLELEYEGFYARGFFVTKKKYALIDEEGKIVTRGLEIVRRDWSEIAKETQAKVLEAILKHGNVDEAVKIVKEVTEKLSKYEIPPEKLVIYEQITRPLSEYKAIGPHVAVAKRLAAKGVKVKPGMVIGYIVLRGDGPISKRAIAIEEFDPKKHKYDAEYYIENQVLPAVERILRAFGYRKEDLKYQKTKQVGLGAWLKF
What are the official names of this protein?
DNA polymerase 1, Pab polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: MSRB_PSEPK
Sequence: MKKIEKTLDEWRSMLDPEQYQVCRLKGTERPFSGKYNSERRDGIYHCICCGLPLFDAQTKFDAGCGWPSFYAPIEDSAMIEIRDTSHGMIRTEVTCARCDAHLGHVFPDGPPPTGLRYCINSVCIDLRPRD
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: RECX_CORGL
Sequence: MDIQAEKIEKLRKALDNFERAHARGESDFFDHEKEEKKANVRRRALLLLNQRARSVNELSTRLKALEFEEDIINEVIGDLTRSKLLDDEVFATEWVRQRAARRGKSSRALDRELQEKGVDKQTRAAALEQIDQADERDTARAVAVKKARSETKIPQDRADYDKALRRVVGALARRGFPAGMSMDLAREALDARIEDLKN
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBB4_RAT
Sequence: MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGRIQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta-4, Transducin beta chain 4.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family.
Protein: YREP_BUCGU
Sequence: MEKLIEKIIYASRWLMFPVYIGLSFGFILLTLKFFQQIILVIPKILIMSESGLILIVLSLIDIALVGGLLVMVMFSGYENFISKMEINVDKKKLGWMGTMDVNSIKNKVASSIVAISSVHLLRLFMDADKISNDKIMWCVIIHLTFVLSAFGMACIDKMSKKNYS
What are the official names of this protein?
UPF0114 protein in repA1-repA2 intergenic region.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.