PharMolix/UniProtQA huggingface dataset:
Protein: LEXA_OCEIH
Sequence: MTKLSKRQQMIFDFIKSEVKLKGYPPSVREIAVAVGLASSSTVHGHLERLENKGYIRRDPTKPRAIEIIDLEMEQQLPKDEARYAPVIGKVTAGIPITAVENIEEFVPIPSSSAGPDDNVFVLVIDGESMIEAGILDGDMVIVKQQNTAVNGEIVVAMTEENEATVKRFFKEENRIRLQPENATMEPLFYDNVTILGKVIGLYRNIH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: ACPS_BACAN
Sequence: MIVGIGIDIIELNRIEKMLDGKLKFMERILTENERNVAKGLKGSRLTEFVAGRFAAKEAYSKAVGTGIGKEVSFLDIEVRNDDRGKPILITSTEHIVHLSISHSKEFAVAQVVLESSSS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCBP1_ARATH
Sequence: MSNWKTLLLRIGEKGPEYGTSSDYKDHIETCFGVIRREIERSGDQVLPFLLQCAEQLPHKIPLYGTLIGLLNLENEDFVQKLVESVHANFQVALDSGNCNSIRILLRFMTSLLCSKVIQPASLIVVFETLLSSAATTVDEEKGNPSWQPQADFYVICILSSLPWGGSELAEQVPDEIERVLVGIQAYLSIRKNSSTSGLNFFHNGEFESSLAEKDFVEDLLDRIQSLASNGWKLESVPRPHLSFEAQLVAGKFHELRPIKCMEQPSPPSDHSRAYSGKQKHDALTRYPQRIRRLNIFPANKMEDVQPIDRFVVEEYLLDVLFYLNGCRKECASYMANLPVTFRYEYLMAETLFSQILLLPQPPFKTLYYTLVIMDLCKALPGAFPAVVAGAVRALFEKISDLDMESRTRLILWFSHHLSNFQFIWPWEEWAFVLDLPKWAPKRVFVQEILQREVRLSYWDKIKQSIENATALEELLPPKAGPNFMYSLEEGKEKTEEQQLSAELSRKVKEKQTARDMIVWIEETIYPVHGFEVTLTIVVQTLLDIGSKSFTHLVTVLERYGQVFSKLCPDNDKQVMLLSQVSTYWKNNVQMTAVAIDRMMGYRLVSNQAIVRWVFSPENVDQFHVSDQPWEILGNALNKTYNRISDLRKDISNITKNVLVAEKASANARVELEAAESKLSLVEGEPVLGENPAKMKRLKSTVEKTGEAELSLRESLEAKEALLNRALSETEVLLLLLFQSFLGVLKERLPDPTKVRSVQDLKSIGAEDDKPSAMDVDSENGNPKKSCEVGEREQWCLSTLGYLTAFTRQYASEIWPHMEKLESEVFSGEDVHPLFLQAISSALQFPLH
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs).  The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing.  In the CBC complex, ABH1/CBP80 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of CBP20 and lock the CBC into a high affinity cap-binding state with the cap structure.  Involved in flowering regulation, possibly by regulating pre-mRNA splicing of FLC gene.  Acts as a negative regulator of abscisic acid signaling in guard cells.
What are the official names of this protein?
Nuclear cap-binding protein subunit 1, 80 kDa nuclear cap-binding protein, AtCBP80, NCBP 80 kDa subunit, Abscisic acid-hypersensitive protein 1, ABA-hypersensitive protein 1, Protein ENSALADA.
What is the protein family that this protein belongs to?
Belongs to the NCBP1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly nuclear.
Protein: CTAA_BACLD
Sequence: MNKALKGLGIITTIAMLFVLIGGALVTKTGSGMGCGRSWPLCNGSIFPALTLESIIEWSHRFVSGTSGVLVLALAIWTWKKIGHIRETKFLAVMSVVFLILQALLGAAAVVFGSSALIMALHFGISLISFASVLLLTLLVFEADSKQKSESFYIGKTMQFHMIGIIIYTYVVVYTGAYVRHTSSSLACLDFPMCSTENGWLPGKFHEWVQMGHRAAALLLFAWIIAAAVHAARQYKNQKRIYWGWMISLILIILQAASGIAVVYSRLDLGFALAHAFFISCLFGILCYFLLLVARYRRQVQK
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BUB32_ARATH
Sequence: MTLVPAIGRELSNPPSDGISNLRFSNNSDHLLVSSWDKSVRLYDANGDLMRGEFKHGGAVLDCCFHDDSSGFSVCADTKVRRIDFNAGKEDVLGTHEKPVRCVEYSYAAGQVITGSWDKTIKCWDPRGASGTERTQIGTYMQPERVNSLSLVGNRLVVATAGRHVNIYDLRNMSQPEQRRESSLKYQTRCVRCYPNGTGYALSSVEGRVSMEFFDLSEAAQAKKYAFKCHRKSEDGRDIVYPVNAIAFHPIYGTFASGGCDGFVNIWDGNNKKRLYQYSKYPTSIAALSFSRDGGLLAVASSYTFEEGDKPHEPDAIFVRSVNEIEVKPKPKVYPNPPV
What is the function of this protein?
Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments.  Promotes the formation of stable end-on bipolar attachments.  Necessary for kinetochore localization of BUB1.  The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20 (By similarity).
What are the official names of this protein?
Mitotic checkpoint protein BUB3.2, Protein BUDDING UNINHIBITED BY BENZYMIDAZOL 3.2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BUB3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, phragmoplast. Cytoplasm, cytoskeleton, spindle. Note=Accumulates onto both kinetochores and the spindle microtubules in cell arrested in metaphase. Starts to localize at kinetochores in prometaphase I (Pro-MI) stage and maintains the localization until the metaphase I-anaphase I (MI-AI) transition. Associates with unattached kinetochores upon spindle assembly checkpoint (SAC) activation. Present in the phragmoplast midline during the final step of cell division (By similarity).
Protein: OTU2_ARATH
Sequence: MEGIIVRRVIPSDNSCLFNAIGYVMDKDKNKAPELRQVIAAAVASNKEKYNEAFLGKLNEEYCAWILNPDKWGGAIELSILADYYGREIAAYDIQTSRCDLYGQTRNYDERVMLIYDGLHYDALALSPFEGAEEDFDMTIYPVGKDRSIGSIEGLALNLVKDQQRKRSYTDTANFTLRCGVCQIGVIGQKEAVEHAQATGHVNFQEYK
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation (PubMed:24659992).  Cysteine protease with a preference for 'Lys-63' and 'Lys-48' -linked ubiquitin (UB) tetramers as substrates (PubMed:24659992).
What are the official names of this protein?
OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 2, OTU domain-containing protein 2, Deubiquitinating enzyme OTU2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C85 family.
Protein: RFX2_CANAL
Sequence: MSNNPHRTHKRQKSSVSNPGYYFTPETKSEIQQQQPQQQESQQQQQQQQQQHSQTHNIYDNDNYMNYNFPPTSNRPRASTTTGTTSTTHPGSELSHESHSVHTSPLKRTASSELDQPIPAMAPSSPLVSSAPYYYQQPSQQQNLSYHDHHHQQQQQQSTPQGQQLSQQTQSNSQSGVPPPLYGTSSSIPPGSTMQPSTSFAFHTSHSTYNPSFDSSNLYNSAFRLPEYPTTSSSSLLSTTGGKQFQQSSALLPSGTLPPSILGTSSSSHVSALRQHQKNNLSISSHLTLFSLSGNNSSQLQSQGSSFQQSETGVDDTKRSSKESTTIFNDLLFHLTSVDGSNINTFLLSILRKINSPFTLDDFYNLLYNDRQRTLLDNSNYQNRIDKTIVSPSDTDMTVSIINQLLNFFKTPSMLVDYFPNMEDKDNKLANINYHELLRTFLAIKILHDILIQLPISEDDDPQNYTIPRLSIYKTYYIICQKLIASYPSASNTRNEQQKLILGQSKLGKLIKLVYPNLLIKRLGSRGESKYNYLGVMWNANIVQEEIKQLCDEHELNDLNEIFNSDNNNPFASIAPSGSATTGSTPRRGLSHKRTSSKQKIKTEPVAGNPFLQPLQTSHHHHHSHHHHHEEQSQEESLSQQMGEHITAPRLSFLRANSKYPTDVNLSVLDDDNWFVRLSYECYARQPALNRDLIQQIFLKNEFLLNNSSLLQNLMDSIIKPLVMQETYSNVDLVLYLAILLEILPYLLLVKSSTNINLLKNLRLNLLHLINNFNNELKKLDSPKFPIERSTIFLVLVKKLINLNDLLITFIKLINRDNCKTTMSSDIENFLKINSQTVKLDDDDNSFFFNLNTTSMGEVNFNFKNEILSNDLIYTLIGYNFDPTTNSELKSSISMNFINEEINVIDEFFKNDLLNFLSTDFHAGLDDDNGEEDDDEEAGPGSTHPMGATGSQGSLSPEPVSTGNPSVPPTRNTSISEVNAENKRGNEAVLTPKETAKLNSLISLIDKRLLSSQFKSKYPILMYNNCISYILNDILKHIFLKQQQQQLQSSSSQLHDTQPLTQQDTAQGIGSSSSNANNTNSSFGNWWVFNSFIQEYMSLIGELVGLHDNLV
What is the function of this protein?
Transcriptional repressor which regulates DNA damage responses, morphogenesis, and virulence.  Involved in the regulation of filamentous growth through its repression of hyphal-specific genes such as HWP1, ALS3, HYR1, ECE1, and CEK1.
What are the official names of this protein?
RFX-like DNA-binding protein RFX2.
What is the protein family that this protein belongs to?
Belongs to the RFX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CDPD2_VIBCH
Sequence: MATANIAIKQNSSTNIAFIERMPSPSLHRILYNLFSKFSYSLSNSCHFNLKCLNFVMNRMFHMSMEDLSQCTILIVDDSPDNIAFMSQGLAQYYRIKAARSGKVALEILAQYPIDLVLLDIVMPEMSGYEVINQIKHNPHTEHIPVIFLTGKSNPEDEQLGFELGAVDYVFKPVSIPLLKSRVHTHLQNKRSKDILLNQNDYLETEVLRRSGELDRMQDAVVFALASLAETRDPETGNHLLRTQHYVKVLAQRLATTDKYRDVLSPTVIDTYFKAAPLHDIGKVGIPDNILLKPGKLTPDEFTTMRNHALLGKLALEKAEKLSGACTALINVAKEIAMGHHEKWDGSGYPLGLKGDDIPLSARLMALADVYDALICRRVYKEPMSHEEAKAIILQGRGSHFDPMVIDAFLIEEQNFIDIAQKFADEESAMVPIQLGQQASG
What is the function of this protein?
Probable phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP).  Increases motility and decreases biofilm formation in vivo.
What are the official names of this protein?
Probable cyclic di-GMP phosphodiesterase VC_1348.
Protein: RECA_LATSS
Sequence: MAKDERQAALDAALKKIEKNFGKGSIMRMGEKVDTQVSTVSSGSLALDEALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAENAMDPKYATALGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMSQALRKLSGTINKTKTIALFINQIREKVGVMFGNPEVTPGGRALKFYSTVRLEVRRAETIKNGTDMIGNRARIKVVKNKVAPPFKVAEVDIMYGQGISRTGELVDMAVEKDIINKSGSWYSYGSERIGQGRENAKNYLADHEDVEDEVRLKVRAAYGISDVPEEDLPTTEDEQINILPDDSTEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2282_CELJU
Sequence: MALSTPVTDFKQGFLQQLNWLKGFLYLIVQQYQAKACQKSAASLTYMTLFATVPMMTVTYAMFSIIPAFQHLGDQLQNLIFTHVLPNNEQDISRYLKNFSAQARQLTWLGGVFLVVSAYLMLKNIEKNFNAIWGVAQGRRGIANFLLYWAILSLGPLLLGVALAMSTYLTSFRLLVGSYDSLGVLELVFQYVPWLLNWAAFTLLFVAVPNCKVPTRHALVGGLLTTIAFQALKAIFAWIVSHSSFTLVYGAFAALPLFLLWVNMTWMVILGGAVFVHSIKFYQIGLRDRAYPDVFASLLVIWHLHQASLRGQSMSEWQILLLGLSTQQWQRLSKRLLGRHVIAQTQQGDFVLCYDLSLLTLSTLAEWIGQRPDWPGVDELTRELPWGQASEQVLGAVDNARAQSWDLTLSAFFAVNQALDNAPPLAR
What are the official names of this protein?
UPF0761 membrane protein CJA_2282.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SMG9_CAEEL
Sequence: MKKVEILKTSRPSSAGGAARPSTASPTHGAPKIAIKTRPVADDVAPTAATVIEPSQKAMKESVRFLTDFGEISDAISDLLTSSPNFNVISAIGPQGAGKSTLLSMLAGNNSRQMYREYVFRPVSREANEQSRHQTIQIDIYIVNHQIFLDCQPMYSFSIMEGLPKVRGGRFDDSTAMSDTLRLTAFLLYVSHTVLVVSETHYDKVIIDTLRVAEQIRPYLAIFRPKLAIDRKTNLVFIKTKASSIDLAPTVIREREELLRLSFQDSRWLKVSQEPFKTLIVLEEIRVRREHLFEEGDEPDEAASLNEFDEQIAELREELQKNREDFTVETAAMDEKKWLDMCREVIRDKTLHKTLKEYQRAMTDGVRTHFDNGFHAERDANKFFS
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes.
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG9, Suppressor with morphogenetic effect on genitalia protein 9.
What is the protein family that this protein belongs to?
Belongs to the SMG9 family.
Protein: PVLEF_HUMAN
Sequence: MEEDFSSQMKKMALAMGTSLSDKDIELLPTDMRHHGSFNYLKFFKHIRKLHASGQLDDAIHTAFQSLDKDKSGFIEWNEIKYILSIIPSSGPTTPLTDEEAEAMIQAADTHGDGRINYEEFSELIKKEKIPKKK
What are the official names of this protein?
Parvalbumin-like EF-hand-containing protein.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: AROQ_DEIRA
Sequence: MLLILNGPNLNRLGLREPGVYGSQTLEDLERQCEAWGAELEMSVTCRQSNYEGQLLEWVQDAEEQGFTGLVINPGALTHYSYALRDAIAGQRLPVVEVHISNVDAREEFRHQSVTAAVCRGKISGLGFSGYRLAMEYLAEVLE
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: PLSY_BRUC2
Sequence: MAEPGFFNAMLIGALIFGYVLGSIPFGLILTRLAGLGDVRAIGSGNIGATNVLRTGNKKLAAATLILDALKGTAAALIAAHFGQNAAIAAGFGAFIGHLFPVWIGFKGGKGVATYLGVLIGLAWAGALVFAAAWIVTALLTRYSSLSALVASLVVPIALYSRGNQALAALFAIMTVIVFIKHRANIRRLLNGTESKIGAKG
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATB_RHOPA
Sequence: MNAPVKPSKLIKGATGDWEVVIGLEIHAQVSSNAKLFSGAATAFGGDQNTHVSLVDAAMPGMLPVINEECVRQAIRSGLGLNAKIHLRSVFDRKNYFYPDLPQGYQISQYKSPIVGEGEVVVDLPDGDSITVGIERLHLEQDAGKLLHDQHPTSTFVDLNRSGVALMEIVSKPDLRSSEQAKAYVSKLRTIMRYLGTCDGDMEKGSLRADVNVSVRRPGEPYGTRCEIKNVNSIRFIGQAIEYEARRQIGILEDGGTIDQETRLFDANKGETRSMRSKEEAHDYRYFPDPDLLPLEFTQAYVDDLKAGLPELPDAKKERFVHDFGLSVEDAGVLVSERESAEFYEAVLAQLKDQGRDGKLAANWVINELFGRLNKDGQSIDASPVSAAQLAAIVELIGEGTISGKIAKELFEIVWTEGGDPRTLVEQRGMKQVTDLSAIEKVVDDIVAANPDKVAQVVAKPAMLGWFVGQVMKSSGGKANPQAVNDLLKRKLGL
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RL34_AROAE
Sequence: MKRTYQPSVVRRKRTHGFLVRMKTRGGRAVIRARRAKGRHRLAV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: AROA_CAMHC
Sequence: MKIFAQSKPLKATISNIAADKSISHRAVIFSLLSSGTNKIENFLFAEDTEHSLEIARKLGADIEIKEGIVFIDAPKKIVEPDCILECGNSGTSMRLFMGLLASVEGFFVLSGDEYLNERPMKRVGEPLCKVGAKIYGRLDGDKAPLCIQGGKLDFFKFKSKIASAQVKTALILAALNSQGCEYSEPELSRDHSEKMLKKMGADIEISGLNLKVKPLTKPLDPLEIFIPNDPSSAFYYAVAATIIPGSKIILKNMLLNKTRIEAYEVLRKMGANIKFTPKSEIYEQIGDIEISYAPLKAVEVSENISWLIDEAPALAIAFACAKGTSVLRNAKELRVKESDRIKVICEGLKCCGINVTELEDGFKITGGEAEPAIITPYGDHRIAMSFAILGLKCGMIIENSECIATSFPNFGKILKQIGANIED
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF2_MAIZE
Sequence: RVCMGKSQHHSFPCISDRLCSNECVKEDGGWTAGYCHLRYCRCQKAC
What are the official names of this protein?
Defensin-like protein 2, Gamma-zeathionin-2.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
Protein: UPP_UREU1
Sequence: MHKIINHPLIKDKLTRMRKVSTVSTVFRTNLEELTQLMVYEATKDLELNEIEIETPVVKNAKGYKLKNKICLIPILRAGIGMVDGVKSLIPTATIGHIGLYRNEETLKPVEYFKKFPKNISESDVIILDPMLATGGSVVEAVNIIKKYNPKSIKFVCIVAAPEGLEYVQKIHPDVDVYIAALDDKLNENGYITPGLGDAGDRIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: PUR5_PSEPW
Sequence: MSKQPSLSYKDAGVDIDAGEALVERIKGVAKRTARPEVMGGLGGFGALCEIPAGYKQPVLVSGTDGVGTKLRLALNLNKHDSIGQDLVAMCVNDLVVCGAEPLFFLDYYATGKLNVDVAATVVTGIGAGCELAGCSLVGGETAEMPGMYEGEDYDLAGFCVGVVEKAEIIDGSKVATGDALIALPSSGPHSNGYSLIRKILEVSATDIENTQLDGKPLTDLLMAPTRIYVKPLLQLIKQTGAVKAMAHITGGGLLDNIPRVLPKNAQAVVDVASWQRPAVFDFLQEKGNVDEHEMHRVLNCGVGMVICVAQDQVEAALNVLRAEGEQPWVIGRIEQAAEGAAQVELQNLKAH
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_DESHD
Sequence: MNIKPLGDRVVIKALPMEEKTKSGIIMPDTAKEKPQEGEVVAVGPGKMEKGERIVLDVKVGDRVIYSKYAGTEVKYDGQEYLILKETDILAVIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_DEHMB
Sequence: MAIRRICELPEPVLRKKAKKVPSIDGSIQTLIDDMIETMNSADGAGLAAPQVGVSLRLVVFREPDTKEATVLINPEIIKKEGQRQVTEGCLSIPGYFGELTRAETVTAKGLDRHGKACRIKGTGIVAQLLEHETEHLDGILYIDHLESEDQLHEIGPDDEMPEEIRE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: Y880_MYCTO
Sequence: MLDSDARLASDLSLAVMRLSRQLRFRNPSSPVSLSQLSALTTLANEGAMTPGALAIRERVRPPSMTRVIASLADMGFVDRAPHPIDGRQVLVSVSESGAELVKAARRARQEWLAERLATLNRSERDILRSAADLMLALVDESP
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator MT0903.1.
Protein: NUD23_ARATH
Sequence: MLKAVQILGWSSGLTISQRLTKTRKSSTVSFISSSLNLSSVTSSSPRRIFSFKPTRMSSSLPGSDPVANSPTFVSVQSAGDVRKIKFCQWCGGPTKHEIPDGEEKLRAICTHCGKIAYQNPKMVVGCLIEHEGKVLLCKRNIQPSHGLWTLPAGYLEVGESAAQGAMRETWEEAGATVEVISPFAQLDIPLIGQTYVIFLAKLKNLHFAPGPESLECRLFALDEIPFDSLAFSSIYVTLNLYLEDLKKGKLKFHYGTINKRPGSSPSDIRAFSLDYHLQP
What is the function of this protein?
Mediates the hydrolysis of some nucleoside diphosphate derivatives.  Can use FAD and ADP-ribose as substrates.
What are the official names of this protein?
Nudix hydrolase 23, chloroplastic, AtNUDT23, ADP-ribose pyrophosphatase, FAD diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: K2C8_PROAT
Sequence: MTSYQRTVTVRSSTAPKSFTSRSYTGGRFATKASTGPLSLGSVYGGGSGRIGATTAFSTSTSYGGGSSFSGISAGTGFPPITNVTVNKSLLAPLNLEIDPRIGQVRLEEKEQIKTLNNQFAGFIDKVRYLEQQNKLLETKWQLLQNQTTPSRSNLDSMFEAYISNLRRQLDTLGQEKGKLEAELHNMQGLVEDFKNKYEDEINKRTDTENEFVLIKKDVDEAYMNKVELEAKLEALTDEINFLRQIYDEEIRELQTQIQDTSVIVQMDNNRQLDLDNIIAEVRAQYEDMAKKSRAEAETYYQQKYEELSSSAGKYGDDLRNTKNEIAELTRYINRLNSDIDALKGQRANLEAAIAEAEERGEQAVKNAQAQLQELQNALTQAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLASGIQAATVQVNQSSYSGVRAPILSSGFGSGSFQTSSYSSFPLETSYSSPKKSIIVKTIESRDGKIVSERSNIVKE
What is the function of this protein?
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
What are the official names of this protein?
Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.
Protein: LIPA_POLNA
Sequence: MSTPEVVREVQSLETYNPLAKQKAAAKLSRIPVKVVQGEILKKPDWIRVKAGSPSTRFYEIKQILRENKLNTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDADEPLNLARTIAALKLKYVVITSVDRDDLRDGGSGHFVECIQRIRELSPGTTIEVLVPDFRGRDDRALEILKTSPPDVMNHNLETAPRLYKEARPGSDYQFSLNLLKKFKALHPDVPTKSGIMVGLGETDEEILQVMQDMRDHGINMLTIGQYLAPSTSHLPVRRYVHPDTFKMFEEKAYEMGFSHAAVGAMVRSSYHADQQAHAAGVSDKPAE
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_ROSDO
Sequence: MLLAIDCGNTNTVFSLWDGTRFVATWRTSTEWQRTADQYYVWLRTLMQFQKLEVEITDVIISSTVPRVVFNLRVFADRYFNTRPLVVGKPDCLLPVDVRVDEGTQVGPDRLVNTVAGFDLFGGDLIMVDFGTATTFDVVDTDGAYVGGVIAPGVNLSLEALHQAAAALPHVDITKPQSVVGTNTVACMQSGVFWGYVGLVREICERIKAERARDMRVISTGGLAPLFQQTEALFDAYQEDLTMHGLTVIYKYNKETE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCYA_PANIN
Sequence: DALGTGNAQKQQDINHLLDKIYEPTKYPDLKEIAENFNPLGDTSIYNDHGAAVETLMKELNDHRLLEQRHWYSLFNTRQRKEALMLFAVLNQCKEWYCFRSNAAYFRERMNEGEFVYALYVSVIHSKLGDGIVLPPLYQITPHMFTNSEVIDKAYSAKMTQKQGTFNVSFTGTKKNREQRVAYFGEDIGMNIHHVTWHMDFPFWWEDSYGYHLDRKGELFFWVHHQLTARFDFERLSNWLDPVDELHWDRIIREGFAPLTSYKYGGEFPVRPDNIHFEDVDGVAHVHDLEITESRIHEAIDHGYITDSDGHTIDIRQPKGIELLGDIIESSKYSSNVQYYGSLHNTAHVMLGRQGDPHGKFNLPPGVMEHFETATRDPSFFRLHKYMDNIFKKHTDSFPPYTHDNLEFSGMVVNGVAIDGELITFFDEFQYSLINAVDSGENIEDVEINARVHRLNHKEFTYKITMSNNNDGERLATFRIFLCPIEDNNGITLTLDEARWFCIELDKFFQKVPKGPETIERSSKDSSVTVPDMPSFQSLKEQADNAVNGGHDLDLSAYERSCGIPDRMLLPKSKPEGMEFNLYVAVTDGDKDTEGHNGGHDYGGTHAQCGVHGEAYPDNRPLGYPLERRIPDERVIDGVSNIKHVVVKIVHHLEHHD
What is the function of this protein?
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
What are the official names of this protein?
Hemocyanin A chain.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family. Hemocyanin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.