PharMolix/UniProtQA huggingface dataset:
Protein: IF1_YERP3
Sequence: MAKEDNIEMQGTVLDTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFI_ORYSJ
Sequence: MAAVSEVEVDGVVFPPVARPPGSGHAHFLAGAGVRGVEIAGNFIKFTAIGVYLEEGAAVPALAKKWAGKSADELAADAAFFRDVVTGDFEKFTRVTMILPLTGEQYSDKVTENCVAAWKAAGVYTDAEGAAADKFKEAFKPHSFPPGASILFTHSPPGVLTVAFSKDSSVPEGAVAAAAIENRALCEAVLDSIIGEHGVSPAAKRSIAARVSQLLKAESTGDVAAAEPAPVSA
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).
What are the official names of this protein?
Chalcone--flavanone isomerase, Chalcone isomerase.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.
Protein: PHMT_MYCTU
Sequence: MAFSRTHSLLARAGSTSTYKRVWRYWYPLMTRGLGNDEIVFINWAYEEDPPMDLPLEASDEPNRAHINLYHRTATQVDLGGKQVLEVSCGHGGGASYLTRTLHPASYTGLDLNQAGIKLCKKRHRLPGLDFVRGDAENLPFDDESFDVVLNVEASHCYPHFRRFLAEVVRVLRPGGYFPYADLRPNNEIAAWEADLAATPLRQLSQRQINAEVLRGIGNNSQKSRDLVDRHLPAFLRFAGREFIGVQGTQLSRYLEGGELSYRMYCFTKD
What is the function of this protein?
Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL).
What are the official names of this protein?
Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase family.
Protein: DEF_ECOLU
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLKARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RRAAH_HALHL
Sequence: MALLTTDLCDAYADEPGAQLRAMNPMLIGYGGRARFGGPVTTLKLFEDNVRVRELLSAPGDGGVLVVDGGGSMRCALLGDRLAELGRENGWSGAIIYGCVRDSAELAQIDFGVQALNTHPLKSQKKGLGERDVSVTFAGVTIQSGDWLYADEDGVVVASRELTL
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: CREB_ECOLI
Sequence: MQRETVWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKARKQVPDVMILDVGLPDISGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYVAKPFSPREVCARVRTLLRRVKKFSTPSPVIRIGHFELNEPAAQISWFDTPLALTRYEFLLLKTLLKSPGRVWSRQQLMDSVWEDAQDTYDRTVDTHIKTLRAKLRAINPDLSPINTHRGMGYSLRGL
What is the function of this protein?
Member of the two-component regulatory system CreC/CreB involved in catabolic regulation.
What are the official names of this protein?
Transcriptional regulatory protein CreB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_PROMH
Sequence: MSASGEALTTRDYIGGHLNNLQLDLRTFELVNPHAENTPSFWVLNIDSLFFSVLMGLLFLWIFRKVAVKATSGVPGKFQTAVEMVIGFVDSSVRDMYHGKSKVIAPLALTVFVWVLLMNALDLLPIDFIPYIGEHILGLPALRIVPTADVSITLSMAIGVFILILFYSIKMKGVKGFTKELTLQPFNHPVFIPINLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWLLSLPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VP9_MYRV9
Sequence: MSFTVVGSNIYDTTLLMTRKGQNGAPDEVIPRPGFLTLLLNDIDSLRTRVELHNLIDNLNLATNEDYVKFAEYRTLFSQTTDMIRLAYTNGQPAVQTRATDSRTGSVFYANTLTGDKAGNLFRLLAPIAYRYLDVGLPRLFSYIHAQIGTTPAFRYNFDIQPIIKLAITNEPLDYGEWIGQEGIHELERNVMIILSCSNITILAVLSIVGLGVGSHIMTSAADQEAWVGSPFMLSTDNFGNARPFTAPNPSYAQTLRLPIPRIFSAPNRPVWVQSKTSETQSVSGSTHSDEKLTAPM
What are the official names of this protein?
Uncharacterized protein VP9.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: NST1_MAGO7
Sequence: MKGNRRQPAVASQPTSPASPTPSKGTSKYANRDGSKIISVPKPSLSVETPQPSPTVSASMPPPTAGKGQPPSTAPTAPSGSNASGGEAAPTVNRKKAKRRAKLAAKAAAEAGLSGDNLSNGVAAHSASSSLPKQPSDAGHSDNEGEALSRPSQTNGHTSTGASKSKKGRKSKNEDGRFMDSAGSATGSNHHAEMRRPPSPIPHASPGRASGISKEKIWNTSSQEERQRIKEFWLGLGEEERKSLVKVEKDAVLKKMKEQQKQTCSCTVCGRKRTAIEEELEGLYDAYYEELESFANQPNPNGDVPPMLGPTGHFGSTAYTSQIMPSKYPPRQPSRGRIVEHCGDDEDDDGEDEYSEEELDDDEDYSDDEEPEEMHRQRPTEYQTDFFNFGNSLTVQGTRFHESLNSLPPYAKSYMEQVLKYVFRRDVDHSLGGILTVADDLLKNDGKKFIEMMEQLAERRMQREEDAKEQFARNYHINGNNYPAHAHPPPPEDDEEYEDEEEEEEYDSQDEEYDEEEVQTNPVHCACHCPCRGGDYGDAGMSASADDGSYQDHGQESHAKQHRHLQDSMTEEQRMEEGRRMFQIFAARMFEQRVLTAYREKVAKERQEKLLEELAQEDRETEKRKAKKQKEAQKRRDKALQKKQAQAEEKARKDAEKAAEEAERLAEEQRRQEEQRQKNEERKKKKEAQRKAEEEERQRKEAERLRRAQEQKERQAEQDRKAREAKEKEKKAKEEAKQREKAARELKEREARERKEKADKERLEKEAKIKAEKEAREAQRKAERASQKATTLANVPVPTGPARRQSQAPNPAPALPQSQQASVASPQLPTAVPALPKLPTPQKPRRTSQQEPFTSGFAAQQVHGQGAGQYPAPPKAATPVHTSPGPGGLLSKGSSSQGQSLHSQATSPLGTSLPTSTSLPTPFGMPHPPPNQHYPPGIGPLNAPPGLGGPRLFNDYPEQMYQQSPFGFRQATQQHPQLPPGLGIPMGPGRGLGHGPPPPPGLSAQQSDFPNMPASIFGSIPKEPSPLSSHSRQASANFDSPIAATPIARPTPIGRPGSVVQGRRGSSDSPGRPGQPGQDNLEEISAPHLGSSALLDDLDEPLMDDFMQDTRSARRSIPGPPQSSRFPPPAVGSFPMSNSPFGPSLWSQPGPSLVNQGFGGSFGQPAPPPGFNSLSDALSVNSPWTFASRPPPRHNLPQMRKVLIQACLDLASTKTPLLDEKAEDPSRRYLPITAVKKCVDTKFASGSTFTVDDLMSMTNTEGNANNGGGSFDTQEFDGELCVRWVPDDIGDSRTVGRSVGEIGSPIVGSRG
What is the function of this protein?
May act as a negative regulator of salt tolerance.
What are the official names of this protein?
Stress response protein NST1.
What is the protein family that this protein belongs to?
Belongs to the NST1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_GRABC
Sequence: MNGTMTSYCLALLGGYLLGSIPFGLILTRLSGAGDIRKIGSGNIGATNVLRTGRKGLAATTLLLDGGKGAAAALLAVHLGGWALALPAGIAAVIGHLFPVWLGFRGGKGVATGLGVLLATAWPVGLICCALWFAVARTIKISSAAALCAFAFAPLLALAVGGMGLGPPPLAQSHWQAAAAFMLIAVLVFLRHADNIARLRAGTESRIGTRS
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMN_GEOTN
Sequence: MTNTAARRSTGEAQLLPLPSIYSLTLDELKEWLVAHGEKPFRATQIYEWLYGKRVTDFAEMTNLPKRLREQLASAFSITTLKTIVKQTSKDGTIKFLFELHDGYSIETVLMRHNYGNSVCVTTQVGCRIGCTFCASTLGGLKRHLEAGEIVAQVVQVQKALDETEERVSSIVVMGIGEPFDNYDALIKFLRIVNHSKGLNIGARHITVSTSGIIPKIYQFADEGMQINFAISLHAPTTELRTKLMPINKAYPLPKLMEAVRYYIEKTGRRVTFEYGLFGGVNDQLEHAEQLAELLKGLKCHVNLIPVNYVPERNYVRTPRNQIFAFERALKKHGINVTIRREHGHDIDAACGQLRAKERKEETR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_CHLPM
Sequence: MAHKKGGGSTKNGRDSNPKYLGVKAAGGSTVAAGTIILRQRGTVIKPGVNAGIGRDHTIFALEDGVVTFRNGRNNKKQVDIIAP
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SRSF4_MOUSE
Sequence: MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSHSRSKSRSRSQSRSRSKKEKSRSPSKDNKSRSRSRSPDKSRSKSKDHAEDKLQNNDSAGKAKSHSPSRHDSKSRSRSQERRAEEERRRSVSRARSQEKSRSQEKSLLKSRSRSRSRSRSRSKDKRKGRKRSRDESRSRSRSKSERSRKHSSKRDSKVSSSSSSSKKKKDTDHSRSPSRSVSKEREHAKAESGQRGSRAEGESEAPNPEPRARSRSTSKSKPNVPAESRSRSKSASKTRSRSKSPSRSASRSPSRSRSRSHSRS
What is the function of this protein?
Plays a role in alternative splice site selection during pre-mRNA splicing.  Represses the splicing of MAPT/Tau exon 10 (By similarity).
What are the official names of this protein?
Serine/arginine-rich splicing factor 4, Splicing factor, arginine/serine-rich 4.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: RL16_DESRM
Sequence: MLIPKRVKYRKQHRPRGNGGVSKGGREVSFGEYGIQALEAGWITNRQIEAARIAMTRYIKRGGKVWIRIFPDKPITQKPAETRMGSGKGAPEHWVAVVKPGRVMFEVAGVPEATAREAMRLAMHKLPVKCKFVVRGEVGEANES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ATPB_MYCTU
Sequence: MTTTAEKTDRPGKPGSSDTSGRVVRVTGPVVDVEFPRGSIPELFNALHAEITFESLAKTLTLEVAQHLGDNLVRTISLQPTDGLVRGVEVIDTGRSISVPVGEGVKGHVFNALGDCLDEPGYGEKFEHWSIHRKPPAFEELEPRTEMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELAEANVLKDTALVFGQMDEPPGTRMRVALSALTMAEWFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQAVYVPADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTILDPSVVGDEHYRVAQEVIRILQRYKDLQDIIAILGIDELSEEDKQLVNRARRIERFLSQNMMAAEQFTGQPGSTVPVKETIEAFDRLCKGDFDHVPEQAFFLIGGLDDLAKKAESLGAKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YHEG_BACSU
Sequence: MKIALLGASGRVGQAFLTQAAADERFDIFALIRSQHADLPLSKDRTVMGNARRLEDVKKIMENAEIVISCLGTDGDDTLSTAMAHILSVMEEQHIKRLITIGTAGILDSRYEPGKYRFETNESKRKQTRAAKEHAKVYEMLKESSLDWTIICPTYLPDGTATGVYRTERNVLPEGGTSISVGDTADFLYRELVTGEYVGNRVGLAY
What are the official names of this protein?
Uncharacterized protein YheG.
Protein: TRPD_CORJK
Sequence: MSPTTPRSVEPSGLKPEQLPPSYFTWPGLLGRLGNGQELSEAQVRWAMNEIMEGNATDAQIAAFAFGIRVRGITAAELAAAAETMTSFATPVDFSDVPNCVDIVGTGGDGHHTVNISTMASFVVSAAGVPVVKHGNRAASSKCGGADMLEALGLDIERSPEDIRQDAHDTGFAFMFAKTYHPAMRFAGPVRSQLGAPTIFNLLGPMTNPAYPKFGLIGCAFKEFMPIMGGAFARQGSRVLVVRGMDGMDEISVCTPTEVVTVDAAGRTGEEVINPRNVGLDFYEDGSLVGGDAEYNADVAVRLMKGEISGAIKDAVLINAAGALTAVRGWEENGFQETLREQVQIAREALESGAALKQMEKIVGKEF
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: MOAC_PSEPK
Sequence: MLTHLDSQGRANMVDVTEKAVTEREATAEARVRMLPQTLQMIVDGEHPKGDVFAVARIAGIQAAKKTSDLIPLCHPLMLTSVKVELSAEGQDAVRIVARCKLAGQTGVEMEALTAASVAALTIYDMCKAVDKGMVIEQVRLLEKLGGKSGHYKVEA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: LTRA_LACLC
Sequence: MKPTMAILERISKNSQENIDEVFTRLYRYLLRPDIYYVAYQNLYSNKGASTKGILDDTADGFSEEKIKKIIQSLKDGTYYPQPVRRMYIAKKNSKKMRPLGIPTFTDKLIQEAVRIILESIYEPVFEDVSHGFRPQRSCHTALKTIKREFGGARWFVEGDIKGCFDNIDHVTLIGLINLKIKDMKMSQLIYKFLKAGYLENWQYHKTYSGTPQGGILSPLLANIYLHELDKFVLQLKMKFDRESPERITPEYRELHNEIKRISHRLKKLEGEEKAKVLLEYQEKRKRLPTLPCTSQTNKVLKYVRYADDFIISVKGSKEDCQWIKEQLKLFIHNKLKMELSEEKTLITHSSQPARFLGYDIRVRRSGTIKRSGKVKKRTLNGSVELLIPLQDKIRQFIFDKKIAIQKKDSSWFPVHRKYLIRSTDLEIITIYNSELRGICNYYGLASNFNQLNYFAYLMEYSCLKTIASKHKGTLSKTISMFKDGSGSWGIPYEIKQGKQRRYFANFSECKSPYQFTDEISQAPVLYGYARNTLENRLKAKCCELCGTSDENTSYEIHHVNKVKNLKGKEKWEMAMIAKQRKTLVVCFHCHRHVIHKHK
What is the function of this protein?
Multifunctional protein that promotes group II intron splicing and mobility by acting both on RNA and DNA.  It has three activities: reverse transcriptase (RT) for intron duplication, maturase to promote splicing, and DNA endonuclease for site-specific cleavage of recipient alleles.  The intron-encoded protein promotes splicing by facilitating the formation of the catalytically active structure of the intron RNA.  After splicing, the protein remains bound to the excised intron lariat RNA, forming ribonucleoprotein particles, and cleaving the antisense strand of the recipient DNA in the 3' exon.  After DNA cleavage, retrohoming occurs by a target DNA-primed reverse transcription of the intron RNA that had reverse spliced into the sense strand of the recipient DNA.  It also contributes to the recognition of the DNA target site and acts as a repressor of its own translation.
What are the official names of this protein?
Group II intron-encoded protein LtrA.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the bacterial reverse transcriptase family.
Protein: PKHO1_CHICK
Sequence: MEKNNSAKRGQQDGNQQSAQPEKVGWVRKFCGKGIFREIWKNRYVVLKGDQLYISEKEVKDEKNVQEAFDLSDYEKCEELRKSKSRSKKNHSKFTLAHSRQPGNMAPNLIFLAVSPEEKESWINALNSAITRAKNRILDEVTVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTSTSDGMLTLDLIQEEDASPEEHSTCEESFRVDLDKSVAQLAAGRRRSDSENVKLSEKGRSGTLPRHEVTSWDKPTQRKDSLDKGTVYTPQVPKKLSHSEKNKCASMEEILSRRDSAHRAVLRRGLEAHCTAAEPEQLSRLQELVALKLEKTQELLTEVKGYGEGKRKVKDCATSTTTSSSSSSSRSDCERILQESERLLGEASSTWSQARRVLQEVRELRDLYRQIELQQVDCNPKQSSQYRKSMM
What is the function of this protein?
Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP).
What are the official names of this protein?
Pleckstrin homology domain-containing family O member 1, PH domain-containing family O member 1.
What are the subcellular locations of this protein?
Membrane. Nucleus. Cytoplasm.
Protein: CYC_WHEAT
Sequence: ASFSEAPPGNPDAGAKIFKTKCAQCHTVDAGAGHKQGPNLHGLFGRQSGTTAGYSYSAANKNKAVEWEENTLYDYLLNPKKYIPGTKMVFPGLKKPQDRADLIAYLKKATSS
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: DSBB_YERPA
Sequence: MLQFLNRCSRGRGAWLLMALTAFLLELTALYFQHIMLLQPCVMCIYERVALFGILGASLLGAIAPRSPLRYLAIAVWIYSAWKGVQLAWAHTMLQLNPSPFNTCDFFVNFPSWLPLDKWLPAVFAASGDCSERQWQFMSLEMPQWLVGIFAAYLVIAVLVLISQFVKPKRRDLFGR
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YQGF_STRAW
Sequence: MGMRRGRRLAVDVGDARIGVASCDPDGILATPVETVPGRDVPAAHRRLKQLVEEYEPIEVVLGLPRSLKGGEGPAAVKVRAFAQELARVIAPVPVRLMDERMTTVTASQGLRASGVKSKKGRSVIDQAAAVIILQQALESERVSGKAPGEGVEVVI
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSH_SALSV
Sequence: MSQLDLNALNELPKVDRVLALAETNAQLETLTAEERVVWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_CORK4
Sequence: MHRTHLAGELRSHHVGQTVTLSGWVARRRDHGGVIFIDLRDRSGLAQVVFRDSDVAAQAHHLRSEYCIRVTGVVDARPEGSENPNLDSGAIELNVNELTILNSSEALPFQIDDQSSSGEVGEETRLKYRYLDLRRKTQHDALVLRSNVNQAARSVLLKHDFHEIETPTLTRSTPEGARDFLVPARLRPGSFYALPQSPQLFKQLLMVGGMERYFQIARCYRDEDFRADRQPEFTQLDVEMSFVDQDDVISVAEEILTAIWKEIGYDIPTPIPRMTYADAMKYYGSDKPDLRFDIKIVECTEFFANTTFRVFQNPYVGAIVMEDGASQPRRQLDAWQDWAKQRGAKGLAYILVGDDGQLSGPVAKNITDAEREGIADHVGAKPGDCIFFAAGDAKSSRALLGAARGEVARKLGLIKEGDWAFTWVVDAPLFEPAADATAEGDVALGHSAWTAVHHAFTSPKPECMDSFDKDPGSALSYAYDIVCNGNEIGGGSIRIHRSDVQQRVFNVMGISDEEAQEKFGFLLEAMKFGAPPHGGIAFGWDRIVSLLGGFESIRDVIAFPKSGGGVDPLTDAPAPITPEQRKESGIDAKPKKKETKN
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFNMT_HUMAN
Sequence: MNLLPKSSREFGSVDYWEKFFQQRGKKAFEWYGTYLELCGVLHKYIKPREKVLVIGCGNSELSEQLYDVGYRDIVNIDISEVVIKQMKECNATRRPQMSFLKMDMTQMEFPDASFQVVLDKGTLDAVLTDEEEKTLQQVDRMLAEVGRVLQVGGRYLCISLAQAHILKKAVGHFSREGWMVRVHQVANSQDQVLEAEPQFSLPVFAFIMTKFRPVPGSALQIFELCAQEQRKPVRLESAERLAEAVQERQQYAWLCSQLRRKARLGSVSLDLCDGDTGEPRYTLHVVDSPTVKPSRDNHFAIFIIPQGRETEWLFGMDEGRKQLAASAGFRRLITVALHRGQQYESMDHIQAELSARVMELAPAGMPTQQQVPFLSVGGDIGVRTVQHQDCSPLSGDYVIEDVQGDDKRYFRRLIFLSNRNVVQSEARLLKDVSHKAQKKRKKDRKKQRPADAEDLPAAPGQSIDKSYLCCEHHKAMIAGLALLRNPELLLEIPLALLVVGLGGGSLPLFVHDHFPKSCIDAVEIDPSMLEVATQWFGFSQSDRMKVHIADGLDYIASLAGGGEARPCYDVIMFDVDSKDPTLGMSCPPPAFVEQSFLQKVKSILTPEGVFILNLVCRDLGLKDSVLAGLKAVFPLLYVRRIEGEVNEILFCQLHPEQKLATPELLETAQALERTLRKPGRGWDDTYVLSDMLKTVKIV
What is the function of this protein?
Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2) at two different positions, and is therefore involved in the regulation of mRNA translation (PubMed:30612740, PubMed:30143613).  Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2' (PubMed:30143613).  Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55' (PubMed:30612740, PubMed:30143613).  Has no activity towards core histones H2A, H2B, H3 and H4 (PubMed:30612740).  Negatively regulates cell proliferation at G1/S transition via transcriptional suppression of cell cycle regulatory genes such as CDK4 and CDK6 (PubMed:26763933).
What are the official names of this protein?
eEF1A lysine and N-terminal methyltransferase, eEF1A-KNMT, Methyltransferase-like protein 13.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: ISPE_METI4
Sequence: MSTSNYINSFAPAKINLGLRIFGKRKDGYHELQTLMAPISIGDRIEITLLSSGIEFESTGDFDVPKDSSNLALKAALLFLSHHGLKTGLRIKLTKIVPPGAGLGGGSSDAAAVLFSLNRMLAIDETMENLIRLAAQLGSDVPFFLLRKPALCTGRGEILHPTSSFPYPRKGLLIYPGFPVSTPWAYKTYDELCKKGLILPSPSQESDKPVNDLEEAVFSKYLWLPAVKKWIQSHFNPEVCLMSGSGSSVFALFSKEDPRFFNDLIQQAQAYLGPGCWIRLFEILEQF
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: KDSA_PSEAB
Sequence: MAQKIVRVGDIQIGNDLPFVLFGGMNVLESRDLAMQVCEEYVRVTEKLGIPYVFKASFDKANRSSIHSFRGPGLEEGMKIFEEIKKTFKVPVITDVHEPFQAQPVAEVCDIIQLPAFLSRQTDLVVAMARTNAVINIKKAQFLAPQEMKHILTKCEEAGNDRLILCERGSSFGYNNLVVDMLGFGIMKQFEYPVFFDVTHALQMPGGRADSAGGRRAQVTDLAKAGLSQKLAGLFLEAHPDPEHAKCDGPCALRLNKLEAFLSQLKQLDELIKSFPAIETA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.