PharMolix/UniProtQA huggingface dataset:
Protein: CLPP1_TROWT
Sequence: MYPNSRYILPSLDERTAYGYKQVDPYTKLFEDRIVFLGVQIDDASADDVMAQLLVLEGQDAERDIIMYINSPGGSFTAMTAIYDTMQYIRPQIQTVCLGQAASAAAVILSAGTPGKRLALPNARILIHQPVVASSGYGQASDIEIQAREIMRMREWLEKTLAQHSNKSVKQVSKDIDRDKILSSEQALEYGLIDQILVSRKAGLGKK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CL029_BOVIN
Sequence: MRRLGSVQRKMPCVFVTEVKEEPSTKREHQPFKVLATETLSHKALDADIHNAIPTEKVDGTCCYVTNYKGQPYLWARLDRKPNKLAEKRFKNFLHLKQNSKEFFWNVEEDFKPVPECWIPAKEIEQINGNPIPDENGHIPGWVPVEKNSKQHCWHSSVVDYESEIALVLRHHPDDPGLLEISAVPLSDLLEQTLELIGTNINGNPYGLGSKKHPLHLLIPHGAFQIRNLPTLKHSDLLSWFDGCREGKIEGIVWHCNDGCLIKVHRHHLGLCWPIPDTYMNSKPVIINMNLNKYEYAFDAKCLFNHFSKIDNQKFGRLKDIILTV
What are the official names of this protein?
Uncharacterized protein C12orf29 homolog.
Protein: THII_PSESM
Sequence: MKLIVKVFPEITIKSPPVRKKFIRQLGKNIRTVLRELDADIVVGGVWDNLEVETRLTDPKVLQGIRDRLSCMPGIANFLQVAEYPLGDMDDVVAKCKLHYADLLPGTMFSVRCKRAGRHDFSSMDVEKYVGSQLRMQCGAAGIELKKPDLVVRMEIRDQRLFVVHDQHKGMGGYPLGALEQTLVLMSGGFDSTVAAYQIMRRGLMAHFCFFNLGGRAHELGVMEVAHFIWKKYGSSQRVLFVSVPFEEVLGEILQKVDNSHMGVVLKRMMLRAASAVADRLEIDVLVTGEAISQVASQTLPNLSLIDAATDKLVLRPLVATHKQDIVDLATEIGTADFARHMPEYCGVISVNPKTNAKRNRVEYEEQQFDMAILEQALERAKLVSIDRVIDDLSRNIDIEEVSQALAGQVIIDIRHPDAQEDQPLQVPGVEIQTLPFYALNSRFKALDDTRQYLLYCDKGVMSRLHAHHLLSEGHANVRVYRPS
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPB1_YEAST
Sequence: MPQASTFGSHSLEAHPLHIQPAVHIKLSKEERSHYREQYDSLKYISNYVSVFDQALSDNIDSRIRKENEALLKKYYESRKPFTFTSFRQGSVISSSDSSTGFTERTKTYCFLNDFVSNCVNEVDPYTLKMTVRNRNTALNMENLDDERKSKDDIYDFEDNTDDECNAKCHGAFHYSSERLEILRSRSTISYFKYYKKLLTVDLRDSDVLKRHNLWMPMITRRFRFLLVSSSKPEDVRLTTPIPTFSESDLDIFKNKTCPLFINGTDCVPRSYDTFSGSSVIASIFSEYKLPSLSYHCSVELNDQLFIVGGLMACHRYDEEAPDLKDFYVDGIKNLPPPLIPELINNPSMIPNPHLYCFSLTSSRLTRPDISGYIPPPLVCTQGCKLTERHIFLYGGFEIKSETQVDDKGRYFIRKRAFLNNTGYILDTVTFNFSKIELVAPPYQFAIYNNFSPRFGHMQASISNSNNNVSNENTTTSAKGRRSISPYRQGNGDHKIDDLVGSPGSTDYLEDDAIPPVTNPRSTDSLSSKHCSTATHICSSVNTILIFGGYSQTGDDKYEAMNDMWKINIPVVSRGKRNYYKFADTVTATKIPIIDDPELWPSRRAFSACCVPDYFTKDVEPIETRLLRNLKNDFSIDLEIRPGNKPSQPLFPNIPHSRKEKKSGRDSMHISNSNNSTSEDTSSKSTRNTTSSPPTSPKHTPPLNPSKKCASIGRTIAFHGGSDGYDVCSDMWWFDFDSETWTKIDLYAKTQEESDGLVPINLCMVGHSMTTVGHKVVLIGGLRQGDVDRIYRDETLPEEVISGVPLGSGVINVVDLNTQCLQGCKLIRNDGDTKESVIMDPHVGTPHQVLAVAGTIELVKGTMTLIGGVVAGREDISSLYLRGAVLQFILPSMNLAN
What is the function of this protein?
Beta subunit of a guanine nucleotide-binding protein (G proteins).  G proteins are involved as modulators or transducers in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.  Involved in the determination of the cAMP level according to nutritional conditions, most probably as a regulator of cAMP phosphodiesterase.  Required for the control of pseudohyphal and haploid invasive growth.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta 1, Gbeta mimic kelch protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADE_RHOPB
Sequence: MTDLESFIRGLPKTDLHMHIEGSIEPQLMLDLAARNGMKLRWDTAEALRGAYQFDNLQSFLDLYFEGCKVLVAEGDFRDVTRAYLRRAHEDGVVRAELFIGPQSFTERGTPLEALMSGVLGAMQEARREHGLSVGLMISVHRHRTEADAMVMLDQIMPWKDQIIAIGMGGAELGNPPAKFARFFKAARDRGFRTTVHAGEEGPAAYVREALELLQVDRIDHGNACLADPDLVRELAMRRIPLTVCPLSNLRLKGVTEMARHPLKTMMAQGLHVTVNTDDPPYFGGYVTENLLACREALDLSREEIVRLVRNGLEAAFVTTEEREILLRQLDDYLARHAVASTS
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: KITH_STRP8
Sequence: MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDGFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVVDELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGKPVYEGDQIQIGGNETYIPVCRKHYFNPEI
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_PECAS
Sequence: MSSLSKEAVMVHEALLARGLETPLRGALLDRDTRKQRIAEHMTEIMNLLSLDLGDDSLAETPTRIAKMYVDEIFSGLDYANFPKITIIENKMKVDEMVTVRDITLTSTCEHHFVMIDGKATVAYIPKDGVIGLSKLNRIVQFFSQRPQVQERLTQQILVALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRQEFLRAVRHHN
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: CPXE_STRGO
Sequence: MTDTATTPQTTDAPAFPSNRSCPYQLPDGYAQLRDTPGPLHRVTLYDGRQAWVVTKHEAARKLLGDPRLSSNRTDDNFPATSPRFEAVRESPQAFIGLDPPEHGTRRRMTISEFTVKRIKGMRPEVEEVVHGFLDEMLAAGPTADLVSQFALPVPSMVICRLLGVPYADHEFFQDASKRLVQSTDAQSALTARNDLAGYLDGLITQFQTEPGAGLVGALVADQLANGEIDREELISTAMLLLIAGHETTASMTSLSVITLLDHPEQYAALRADRSLVPGAVEELLRYLAIADIAGGRVATADIEVEGHLIRAGEGVIVVNSIANRDGTVYEDPDALDIHRSARHHLAFGFGVHQCLGQNLARLELEVILNALMDRVPTLRLAVPVEQLVLRPGTTIQGVNELPVTW
What is the function of this protein?
Involved in the metabolism of vitamin D3 (calciol) and of a number of sulfonylurea herbicides.  Catalyzes the two-step hydroxylation (25- and 1-alpha-hydroxylation) of vitamin D3 (VD3) to yield its active form 1-alpha,25-dihydroxyvitamin D3 (calcitriol).  The first step is the hydroxylation of the C-25 position of VD3 to produce 25-hydroxyvitamin D3 (calcidiol).  The second reaction is the hydroxylation of the C1-alpha-position of calcidiol to produce calcitriol.  It can also hydroxylate vitamin D2.
What are the official names of this protein?
Vitamin D3 dihydroxylase, CYP105A1, Cytochrome P450-CVA1, Cytochrome P450-SU1, Vitamin D3 hydroxylase, VD3 hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGP_THEKO
Sequence: MTIKAISVDIDGTITYPDRRLHEKALEAIRLAESLGVPVMLVTGNTVQFGEAAAILIGTSGPVVGEDGGALSIKEGKLRKRVYLTNMDEEWILWGELKKRYPEALLSFSMPERKAGLVVLRTVPVKAVRELIKELGLNLIAVDSGFAIHIKKPWINKGTGIEKACEYLGISPKEVAHIGDGENDLDAFGVVGYRVAVAQAPESLKEKADYVTTKPYGEGGAEAIEHILRKFGYLPEEKT
What is the function of this protein?
Catalyzes the dephosphorylation of 2-phosphoglycolate.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the archaeal SPP-like hydrolase family.
Protein: CBIN_SALPB
Sequence: MKKTLMLLVMVVALVILPFFINHGGEYGGSDGEAESQIQALAPQYKPWFQPLYEPASGEIESLLFTLQGSLGAAVIFYILGYCKGKQRRDDRA
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiN, Energy-coupling factor transporter probable substrate-capture protein CbiN, ECF transporter S component CbiN.
What is the protein family that this protein belongs to?
Belongs to the CbiN family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IF5A_METHJ
Sequence: MKEQTEVGKLKEGKYLLVDDEPCKILSISVSKPGKHGAAKARLDVVGIFDGVKRSIVQPVSAKVYAPIVERRNAQVISIAGNVVQMMDLESFENFEVTVTDDVKDRIEAGKETMYIYSMEKRKIDFL
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNFA_SALCH
Sequence: MLKTTLLFFVTALCEIIGCFLPWLWLKRGASVWWLLPAAASLALFVWLLTLHPAASGRVYAAYGGVYVCTALLWLRVVDGVRLTVYDWCGALIALCGMLIIVVGWGRT
What are the official names of this protein?
UPF0060 membrane protein YnfA.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS20_MYCPA
Sequence: MANIKSQQKRNKTNERARLRNKSVKSSLRTAVRAFREAAHAGDKEKAAELLVSTNRKLDKAASKGVIHKNQAANKKSALAQALNKL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PANB_THEFY
Sequence: MSSHTPAPALYGGSANRRVTVQDLAAAKERGERWPMLTAYDALTARIFDEAGIPVLLVGDSAAMVVFGYDSTIPVTLDDMIPLTAAVSRATKRALVVADLPFGSYQAGPEQALESAARLMKEGGAQAVKLEGGHRVIAQVEALVSAGIPVMGHIGLTPQSVNVLGGYRVQGRSEEAAEALLSDAKELERAGVFSVVLECVPARVGAEITRQLTVPTIGIGAGPDTDAQVLVWQDMAGLSPRVAKFVKSYANLAEQLRDAATSFAEEVVAGTFPDEQHSYA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24A_SCHPO
Sequence: MKVEVCSFSGSKVYPGAGRLFVRGDNKVFRFVNKKSESLFLQRKNPRRLSWTVLYRRMHKKGISEEHAKKRTRRTVKHQRGIVGANLDVIKEKRNQRPEVRAAARAAALKQRKDKKAASESEKKAIKAKSAASSARGQAIKNAKAAARH
What are the official names of this protein?
60S ribosomal protein L24-A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: F168B_DANRE
Sequence: MNPVYSPASSGVPYANPKGIGYPAGFPVGYAAAAPAYSPSMYPGANPAFPSGYAPGTPFKMSCSPTTGAVPPYSSSPNPYPAAVYPVRSPYPQQNPYAQQQGTYYTQPLYAAPPHVIHHTTVVQPNGMPAAMYAPPIPPPRPNGVTMGMVGGTTMAMSAGTLLTTHSPTPVAPHPSMPTYRQPATPTYSYVPPQW
What is the function of this protein?
Inhibitor of neuronal axonal outgrowth.
What are the official names of this protein?
Myelin-associated neurite-outgrowth inhibitor, Mani.
What is the protein family that this protein belongs to?
Belongs to the FAM168 family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cell membrane; Multi-pass membrane protein. Cell projection, axon.
Protein: SAM5B_XENLA
Sequence: MGTVHARSLDPLPMNGPDFGSPDDADLVEVEPEKKQEILENKDVVVQRVHFEGLGRTKDDLIAHEIGQVFKAKNLIEVMRKSHEAREKLLRLGVFRNVEVLIDTSEGEDAVPNGLDVTFEVTELRRLTGSYNTMVGNNEGSMVLGLKFPNLFGRAEKMTFQFSYGTKETSYGLSFFKPQVGNFERNFSVNLYKVTGQFPWSSLRETDRGVSAEINFPIWKTSHTLKWEGVWRELGCLARTASFAIREESGHTLKSSLSHTMVIDSRNASILPKRGALLKINQELAGYTGGDVSFLKEDFELQLNKQLAWDSVLSTSLWGGMLVPVGDRPSSIADRFYLGGPTSVRGFSMYSIGPQSEGDYLGGEAYWAGGVHLYTPLPFRPGRGGFGDLFRTHFFLNAGNLCNLNYGEGPRAHLQRLAECIRWSYGAGLVLRLGNIARLELNYCIPMGVQSGDRICDGVQFGAGIRFL
What is the function of this protein?
May play a role in the maintenance of the structure of mitochondrial cristae.
What are the official names of this protein?
Sorting and assembly machinery component 50 homolog B.
What is the protein family that this protein belongs to?
Belongs to the SAM50/omp85 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: HIS2_BURCH
Sequence: MTQSTEDTLLRLAAVIDSRKGGDPDQSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDVRQGGAPSALVGEVADLWFHCLVMLSHFDLSPADVIAELERREGLSGIEEKALRKRREREENGG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPA16_ARATH
Sequence: MKKPSLFQIIIIVLSIPTTTGRTVGNLRVREGSPFKIAIFADLHFGEDTWTDWGPGQDVNSVNVMSAVLDAETPDFVVYLGDVVTANNIAIQNASLFWDKAISPTRDRGIPWATLFGNHDDASFVWPLDWLSSSGIPPLRCPAASDDDGCTFRGTTRVELIQEEIKSSNALSYSMISPKELWPSVSNYVLLVESSDHSKPPVALLYFLDSGGGSYPEVISNAQVEWFKTKSNTLNPYLRIPELIFWHIPSKAYKKVAPRLWITKPCVGSINKEKVVAQEAENGMMRVLENRSSVKAVFVGHNHGLDWCCPYKDKLWLCFARHTGYGGYGNWPRGSRILEISEMPFRIKTWIRMEDGSVHSEVNLTYD
What are the official names of this protein?
Probable inactive purple acid phosphatase 16.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.
What are the subcellular locations of this protein?
Secreted.
Protein: NOP14_SCHPO
Sequence: MGKNGSQLKNLKSSIRQANLGTRPNNKKSRTRSTESHEDRQAKVQKIQSDFNLFDRQFTKRKFDVGGRRVKGTEGKPGVSRGVGEELRRRTIGAELKKRNRSGAIIDRRFGENNPHLSVEEKMLERFSREQQRRSKRELYNLDAEDVLTHGNRPLSDIDSFEEPGFGLDEGEELNDEVVRRMHFGGFEDSDAENEKEGEGAHKSKREVMSEIIAKSKHYKAERQAEKERYEDEREKLDEQMEDLQSFLSDYKKASRKSGIKTQRPIISDGDARYDSFVREMVFDKRAHPTERTKTEEELAQIEADRLRELEDQRISRMEHYQEDSASEAGSIEDEQATDNVFGFGKGLEQENEEEWNGINEEAEESEDEESVNSDTSFVDDEQLKVEEQPLVGSAIKNEGSEKASLAYTYPCPTSHVEFVQLLKGLDYKDYPTVVSRIRTLHHVKLHPDNKSRLENFSVILLQHILHLTRQPMISMELLEHLTEHLHSLAQQFPSALGISFISVVEGMRKRLAKSYVYPEIKFPEISDLLFFNLTGSIFPTSDKKHIVVSPVMLTMAESLSQSPADSLSDVCKKLYIANLFLKFQSYSHRYVPEVITAVSQALYLLYPNFISIVPGTFALPDSLKEKQNLFAIQDISLDEPQRLSLYELEELPTGLLQSSILFITLNLIEMAIDIYFKEQAFIEIFVPIMDMLQLYSLKKELLSKRLSEKLLSTLQAVSDSIESAKANRKPLALQSHRPLGITSQVPKFEEGYSLDKSSHDIDPERAQLNKLRAQHRDAKKGAIRTLRKDARFIARERRQEQRAKDQAYNEKMRKLENRLQHFDPAV
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity).
What are the official names of this protein?
Probable nucleolar complex protein 14.
What is the protein family that this protein belongs to?
Belongs to the NOP14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: OPCA_NOSP7
Sequence: MTKSKISNPKLPMALQTSTIFSLQAPKDISLNEIDAELNQIWQSYGITGEDGGLPSATRATTFTLVVYEPEETQYLLAALGFYNGPIDGILGPQMAAALREVQKKHKLPETGTATQETLTILREEFAKGQRGGTGGEHAIAGLNSGSPRIADEIALRNPCRIIALFPITGEDEGVKAQVSAYCPIQKQSSSTLICCEYITLSGTAAALERIGGMIPALLIGGLPKFLWWKATPDPNNGLFKRLAAICNNVIVDSCNFNEPESDLLRLEELVEAGVPLADLNWRRLASWQELTAEAYDSPKRRAALREIDRVTIDYEKGNPAQALLFLGWLASRLEWQPVSYQKESGDYDITRIHFISQDQRQVEAELAGVPVADVGDIIGDLIALRLSSTNPQADCGTVICSETGGCMRMETHGGAQSAGLFQQVTSLSEQKAEALLSQQVQRWGRESLFEESLGVTANIFKLAN
What is the function of this protein?
May be involved in the functional assembly of glucose 6-phosphate dehydrogenase.
What are the official names of this protein?
Putative OxPP cycle protein OpcA.
Protein: VFE66_ASFP4
Sequence: MLKYIYMHLSHKYNHILFTYNMRIYLIKRNHMLFTHMFTTYAYIM
What is the function of this protein?
Inhibits host protein translation, probably through the EIF2AK2/EIF2S1 signaling pathway (By similarity).  Promotes cell retention in the G0/G1 phase (By similarity).
What are the official names of this protein?
host translation inhibitor E66L, pE66L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus E66L family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum.
Protein: KTHY_PROM9
Sequence: MKGKFIVIEGIDGCGKTTQINELSKWLPKSGLIKKGSKLITTREPGGSLLGKKLRGLILDNNKTNKPSSLAELLLYSADRAEHISKIISPALNNNDWVISDRFSDSTLAYQGYGRKINLEIIKKVESIVCQGEYPDLTFFLEISPEESIMRRKNEIPDRIESEGIRFLEKVNEGFKLIAREKKWKVISASQNIKTISNQIKETLLNNFSNDK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: AKR1_ASPOR
Sequence: MSSGNSSTGTHTNGNFATLGSSPPSAVGGKGRAIPPKVTHEDASVELKTMNPERGAARGSIPLGEDIMQIARIGEVPAMQRLFDEKKFSANHKDEEGITPLHWAAINNQYAMCKFLLDSGADVNAKGGESVATPAMWAAQRCHYYIVHLLLQRGADPLLTDVQGYNILHLATIDGNAFLLVLLLHQEIPVDVVDQQGHTGLMWAAYKGYPALVDLFLRWGAHANAVDEGGLTPLHWALVKGSLPCVLKLIEYGADKFAKTRDGKTPAVVAGEMNTTRVWYRALDEYGYDLDGNAKVSSSGLASWVRNKSLMSKFFFLWPFAIVFAAVWILSNMVVYAAIPMMLVTVFGLQWVAQKAASQGPSEYRILQKTPYLSGVFAGSLFWVGFRYVFYVLPVTYSTSPILNGLFAIFFSLTTYFYIYSMVEDPGFVPKLGSRNQQRAVITELFEQWKFDEENFCVSCMVRRPLRSKHCKRCARCVAKHDHHCPWIDNCVGANNLRHFVLYITCLEVGIVLFVQLTFNYINSLPAPAQPQCNIINETLCDFVLRDTFTLVLDLWVCIQLVWITMLVAVQMIQISRNQTTYENMRGHSVDRSYPSSRAFASAVAAGTTSLNAAGLTSSGQGPNPALAQGAPRHRKHGCLQQWSSLLGIDTFFATARDGLRDGPRAVRPKNPFSRGVVTNCRDFWCDPAPYFGKREPGAAMLGGEVINYNRMYETPSRMHSGGGYQSLSVEDPEQGV
What is the function of this protein?
Palmitoyltransferase specific for casein kinase 1.
What are the official names of this protein?
Palmitoyltransferase akr1, Ankyrin repeat-containing protein akr1.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
What are the subcellular locations of this protein?
Early endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: LYS1_YEAST
Sequence: MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDRHCARVKRSSRL
What is the function of this protein?
Catalyzes the NAD(+)-dependent cleavage of saccharopine to L-lysine and 2-oxoglutarate, the final step in the alpha-aminoadipate (AAA) pathway for lysine biosynthesis.
What are the official names of this protein?
Saccharopine dehydrogenase [NAD(+), L-lysine-forming], SDH, Lysine--2-oxoglutarate reductase.
What is the protein family that this protein belongs to?
Belongs to the AlaDH/PNT family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: ENDUC_XENLA
Sequence: MVYLVFLCLLPSLISGASILPEPRKDVRASATDAEIQSLAEQFYAADTNKAASGDITLNLQYKASSSQTSTGTDYANQKLFRYVNEAKLFARPTFARLVNLLDNYAQKTGSAESVPTTEVNEQNAFLDEIFKTSIITKLSNFFISKGYYSSAASFKTDLKAMWFGLYTRTSGPLDSSGFEHVFHGEIHKGKVSGLHNWVKLYLLEKSGQVNYLSYSADGVWKGYPDIYAFQLKWSTYLKTIGSFFVGSSPEFDIAMYTLCYVTRPDSLCSVKMGGSIFKIQTYTWANSTYGNGKRFVASSYPI
What is the function of this protein?
Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end.
What are the official names of this protein?
Uridylate-specific endoribonuclease C, Placental protein 11 homolog, Protein endoU-C, XendoU-C.
What is the protein family that this protein belongs to?
Belongs to the ENDOU family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRNL2_ARATH
Sequence: MRAAINRANSLGGLFSFRFIRNIKSMSSSTSQDFVSRPVIKKVFAKLQKEGDGAVVRRGISRSEQKLLDPFLMLDEFSVSPPAGFPDHPHRGFETVTYVLEGGITHQDFKGHKGTIYAGDVQWMTAGRGIIHSEMPEEEVNKGLQLWINLSSNEKMIEPNYQELSHSDIPKAEQNGVEVKVIAGESMGIQSPVYTRTPTMFLDFTLQPGAQIHQNVPESWNAFAYILESGEGGGVFSSSNSSPIPAHSVVVFGPGNDGVSVWNKSSSKQLRFVLIAGEPIGEPVVQYGPFVMNTQAEIDMTIEDYHYGKNGFEMAKYWRSQ
What is the function of this protein?
Involved in susceptibility to the bacterial plant pathogen Ralstonia solanacearum.  Stabilizes the xylem cysteine protease XCP2 by blocking its autolysis.
What are the official names of this protein?
Pirin-like protein 2, PIRIN2, Pirin-like protein At2g43120.
What is the protein family that this protein belongs to?
Belongs to the pirin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: ERA_XANAC
Sequence: MSEITSPHRSGSVAVIGRPNVGKSTLTNALVGAKVSIVSNRPQTTRHRLLGIATFPEGQLVLVDTPGLHREQKRAMNRVMNRAARGSLEGVDAAVLVIEAGRWDEEDTLAFRVLSDAGVPVVLVVNKVDRLKDKTALFPFLAQVSEGRTFAAVHPVSALKRKGLDALVGDLLKLVPEAEAMFGEDEITDRSQRFLAGELVREQLMRQLGEELPYATTVEIERFAEDGALLRIGAVIWVEREGQKAIVIGKGGTRLKEIGGKARLQMERLFGAKVFLETWVRVREGWSDDEAALKAFGYE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: Y2305_PECAS
Sequence: MPITANTLYRDTMNFTRNQLISILMMSLLTAFITVILNHALSPSGDELQILSSSSSDLSSSVESGLMDLIQQMTPEQQTVLLKMSAAGTFAALVGNVLLTGGVLMLIQLVSDGQRTSALRAIGASAPFLLRLLFLILLCTLLIQLGMMLLVIPGVLLAIALSLSPVIVVTEKSGIFSAIKTSTKLAYSNLRATAPAIVMWLLAKIAILLIVSKLPISSPTVLSVVLNGLSNLISAILLIYLFRLYMLLRA
What are the official names of this protein?
UPF0259 membrane protein ECA2305.
What is the protein family that this protein belongs to?
Belongs to the UPF0259 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TYSY_PHYMT
Sequence: MQAYLNLCRDILNYGKKKIDRTKTGTRSIFGYQMRFNLEKGFPLLTTKKMNFKAIIHELLWFIKGDTNIRYLVQNNVNIWNEWPYQKYCNSNFFQNLTLQEFIDKIIIDEKFAKIHGDLGPIYGHQWRNFQGIDQLTDLISEIKKNPHSRRLILTAWDPTVIKDMLLPPCHVMIQCYVEKNKISMQLYQRSGDVFLGIPFNIASYSLLLIIIAQCTGLKPFEFIHTIGDAHIYNNHIEQIQKQIKRIPKKLPIMTLNPHIIDINQFTFNDFNLEKYESYGILKGVVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSBP_HUMAN
Sequence: MFRRPVLQVLRQFVRHESETTTSLVLERSLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDSEVYQLGDVSQKTTWHRISVFRPGLRDVAYQYVKKGSRIYLEGKIDYGEYMDKNNVRRQATTIIADNIIFLSDQTKEKE
What is the function of this protein?
Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA) (PubMed:21953457, PubMed:23290262, PubMed:31550240).  In vitro, required to maintain the copy number of mitochondrial DNA (mtDNA) and plays a crucial role during mtDNA replication by stimulating the activity of the replisome components POLG and TWNK at the replication fork (PubMed:21953457, PubMed:12975372, PubMed:26446790, PubMed:15167897, PubMed:31550240).  Promotes the activity of the gamma complex polymerase POLG, largely by organizing the template DNA and eliminating secondary structures to favor ss-DNA conformations that facilitate POLG activity (PubMed:26446790, PubMed:21953457, PubMed:31550240).  In addition it is able to promote the 5'-3' unwinding activity of the mtDNA helicase TWNK (PubMed:12975372).  May also function in mtDNA repair (PubMed:23290262).
What are the official names of this protein?
Single-stranded DNA-binding protein, mitochondrial, Mt-SSB, MtSSB, PWP1-interacting protein 17.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.