PharMolix/UniProtQA huggingface dataset:
Protein: MET_MUSPF
Sequence: MRAPAVLAPGILVLLFTLVQRSCGECKEALVKSEMNVNMKYQLPNFTAETPIQNVVLHKHHIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEHPDCSPCQDCSHKANLSGAVWKDNINMALLIDIYYDDQLISCGSVQRGTCQRHVLPRSNTADIQSEVHCMYSPQADEEPGQCPDCVVSALGTKVLISEKTRFINFFVGNTINSSSHPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQRETLDAQTFHTRVIRFCSVDSGLHSYMEMPLECILTEKRRKRSTREEVFNILQAAYVGKPGAHLAKQIGANLNDDILYGVFARSQPDSAEPMNRSAVCAFPIKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRSDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSSTPHVNFRLDSHPVSPEAIVEHPLNQNGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPPFVQCGWCHDKCVQLEECPTGTWTQEICLPTIYEVFPTSAPLEGGTMLTICGWDFGFRRNNKFDLKKTKVLLGNESCTLTLSESTTNMLKCTVGPAVNEHFNISIIIANGRGTAQYSKFSYVDPIITSISPSYGPKTGGTLLTLNGKYLNSGNSRHISIGGETCTLKSVSDSILECYTPAQTTPTEFPIKLKIDLANREMNSFSYQEDPIVYAIHPTKSFISGGSTITAIGKNLHSVSVLRMGINVHEARRNFTVACQHRSNSEIICCTTPSLQQLSLQLPLKTKAFFMLDGIHSKYFDLIYVHNPVFKPFEKPVMISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCETIYSDSEAVLCKVPNDLLKLNNELNIEWKQAVSSTILGKVIVQPDQNFTGLIVGVISISLIVLLLLGLFLWLKRRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDLSPMLTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDIIDGEGDT
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand.  Regulates many physiological processes including proliferation, scattering, morphogenesis and survival.  Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules.  Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.  Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC.  The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects.  During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation.  In adults, participates in wound healing as well as organ regeneration and tissue remodeling.  Promotes also differentiation and proliferation of hematopoietic cells (By similarity).
What are the official names of this protein?
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NUOH_BUCA5
Sequence: MIWLEENMIKITFCFFKVIFILLLIVFSSAMLSIVERRLLAVFQNRYGPNRVGWMGSLQLCADMIKILFKEDWIPPFSRKFIFVLSPVIAFTSLLCVIPIIPFTSHFVIIDLNIGILFFLMMASLSVYAILFAGWSSNNKYALLGAMRACVQTLSYEVFLGLSLMGVVAQSGSFKISDIVNSQKYIWNVFPQFFGFLTFLIAGLAVCHRHPFDQPESEQELADGYHIEYSGMKFGLFFIGEYISIITVSSLIVTLFFGGWLGPWIPGCIWFILKIIFFIFLFILIRAALPRPRYDQVLLFGWKFCLPLTLFNLFLTAFLILV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UREE_NATPD
Sequence: MRHVDGVVGNRYDDPDLDEQLHAHEDAGRLERVVLEAGQRKRSRLRVETDAGTDLGIVVDQPELRAGDVLFLDDDAAAVVEFESRTAFVVDLPSPGPETVAAAVELGHRVGNQHWDIAIEGGTVYVPVEADRRIIEDVLGEHIPDSGTTRYASVDASLFIGENAEPSGVDHSHEATDSGHGYGEDHDHDHSHDHNHDHDHNHDHDHSHSHDSHE
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALDC_LACLA
Sequence: MTEITQLFQYNTLGALMAGLYEGTMTIGELLKHGDLGIGTLDSVDGELIVLDGKAYQAKGDKTIVELTDDIKVPYAAVVPHQAEVVFKQKFTASDKELEDRIESYFDGQNLFRSIKITGEFPKMHVRMIPRAKSGTRFVEVSQNQPEYTEENVKGTIVGIWTPEMFHGVSVAGYHLHFISEDFTFGGHVLDFIIDNGTVEIGAIDQLNQSFPVQDRKFLFADLDIEALKKDIDVAE
What is the function of this protein?
Converts acetolactate into acetoin.
What are the official names of this protein?
Alpha-acetolactate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the alpha-acetolactate decarboxylase family.
Protein: TRPA_SALTO
Sequence: MSRIGVAFDQARAEGRAVLVGCMPAGFPTVEGSIAAMTAMVEAGVDVIEVEIPYSDPVMDGPVIQRASDVALAGGVRVADTLRIVEAVAATGAPVVTMTYWNPVEQYGVDAFARDLAAAGGTGLITPDLIPDEAQEWLAASDAYGLDRTFLVSPSSTDARLHMTVEQCRGFVYATTIMGVTGARAQASAAAPVLVSRVRAVTDLPVGVGLGIGTGEQASTASSFADGVIVGSALIRRLLDAPNLPAGLTALRELSAELAAGVRTPAP
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: CYB_LAGCR
Sequence: MINIRKTHPLMKILNDAFIDLPTPSNISSWWNFGSLLGLCLIMQILTGLFLAMHYTPDTSTAFSSVAHICRDVNYGWFIRYLHANGASMFFICLYAHIGRGLYYGSYMFQETWNIGVLLLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALAAVHLLFLHETGSNNPTGIPSNMDMIPFHPYYTIKDILGALFLILTLLALTLFTPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILIFIPMLQTSKQRSMMFRPFSQLLFWTLIADLLTLTWIGGQPVEHPYIIVGQLASILYFLLILVLMPTVSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: QUED_AQUAE
Sequence: MKWEISKTFRFEAGHRVWKQNLTYGRGAQFTKEKPVNKCVNLHGHSYVLEVTVGSDTLSEQDMVMDFYHVKNALKGLIEEIDHSFIIDVNDPMYPELKDVAEKYGAMKIFPVEFCPTAEALAKFFYDFLKKRLEEAGLLGEVKVVKVVLWETATSKAEYKEE
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.
What are the official names of this protein?
6-carboxy-5,6,7,8-tetrahydropterin synthase, CPH4 synthase, Queuosine biosynthesis protein QueD.
What is the protein family that this protein belongs to?
Belongs to the PTPS family. QueD subfamily.
Protein: MQO_ECOSM
Sequence: MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAALQQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLNLLEKVFGDRVSSPQWQATLKATVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: GLPK_BORBR
Sequence: MTANEFILALDQGTTSSRAIVFDRAGTVRGMGQREFRQHYPRPGWVEHDAGEIWQSQLEVAREALRNAGASAADLAALGITNQRETTLIWERATGRPLARAIVWQDRRTAAMCEKLLHDGHGRMLQERTGLVVDAYFSGTKLAWLLDHVPGARKMAERGELAFGTVDTWLVWQLTGGAVHSTDPSNASRTMLFDLHAQDWSDDILALLNIPRGILPRIAPSSARIGETLPEWLGGSIPIAGVAGDQQAATFGQACFTPGMAKNTYGTGCFMLMNVGDAPVASRHNLLSTVGWSLPAGNATHATYMVEGGVFMAGAAVQWLRDGLGIIQRSADIEALAASVADTDDVFMVPAFAGLGAPHWDPYARGTLVGMTRGTTRAHIARATLESIALQSAELLSCMNADSGIPLSELRVDGGAARNDLLMQMQADLLGVPVVRPRVPESTALGAAGLAGLAVGFWSSLDEFGAQWQAERTFEPAWPADVREARMQRWRQAVELSKGWSRPAAGHA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: MED4_DROME
Sequence: MSFHLSTKERLLLLIDDIEMIAKELIEQAHQKISSTELVDLLDLLVAKDEEFRKMLELAEEQAKVEEAMDQLRAKVEVHDREIQKLQKSLKDAELILSTAIFQARQKLASINQANKRPVSSEELIKYAHRISSANAVSAPLTWCIGDLRRPYPTDIEMRNGLLGKSEQNINGGTVTHQNSGMPSEQQRTLSGSAGSGSGSGAGGEVPNAFQNQFNWNLGELHMTMGASGNTVALETRAQDDVEVMSTDSSSSSSSDSQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  Required for activated transcription of the MtnA, MtnB and MtnD genes.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 4, Mediator complex subunit 4, dp34.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NQRA_SHEFN
Sequence: MITIKKGLELPIAGGPEQVIHNGPAIRHVATLGEEYIGLRPTMKIKVGDKVQKGQVLFEDKKNLGVKYTALASGTILEINRGARRVLQSVVIAVEGDDSVAFAQYDADKLDTLDAQVVRDNLIDSGLWTALRTRPFSKVPAVDATAAGIFVTAIDTQPLAADPVVVIAQHKEDFANGLKVLARLTEGKVYLCKAQGADIPAANAQVQEFAGKHPAGLAGTHIHHVLPASATRTVWHIGYQDVIAFGQLFTQGVLNTERVVAIGGPKAKKPRLVRTVLGASMAELTADETVGDGVRVISGSVLSGRTAVGPQAYLGRYHQQVSVLEEGDEKELFGWAMPGVDKFSITRSFLGHLSPSRLFNMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLLSGDFDGAVRLGALELDEEDLALCTFVCPGKYDYGSYLRDCLDTIEREG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: NRDR_BACMK
Sequence: MRCPSCFHNGTRVLDSRPVDEGRSIRRRRECESCLSRFTTFERVEESPLIVVKKEGTREEFNKEKILRGLIKACEKRPVSLRQLEEVTQSVERELRNLGISEVKSDMIGEIVMEELRDIDDVAYVRFASVYRQFKDLNVFIEELKDILQKERE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: HFQ_VIBPA
Sequence: MAKGQSLQDPFLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAISTVVPARPVSHHSGDRPQGDRPQEKSED
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: CSGA_BACSU
Sequence: MDVTLGYLRESLSNHLENEVCQRICKKMLAKRYANEEEFVKDLDDNEMSFLNHVLEKEIKYAQNEQDQKRAKELNEVYELLL
What are the official names of this protein?
Sigma-G-dependent sporulation-specific SASP protein.
Protein: SYH_SHESH
Sequence: MAKQIQAIRGMNDILPTQSPLWQKLETVLRETVSAYGYSEIRTPIVESTDLFKRSIGEVTDIVEKEMYTFDDRNGDSLTLRPEGTASTVRAGNEHGLLYNQEQRLWYMGPMFRHERPQKGRYRQFNQFGVEVYGIGSADVDAEVLMLSHRLWEKLGITEHVTLELNTLGDPAERAAYRDALIAYLEQFKEQLDEESQRRMYTNPLRVLDTKNPDVQALLTDAPELMEYLGEETRAHFSHLCELLDAVGIKYVINPRLVRGLDYYNRTVFEWVTSSLGAQGTVLAGGRYDGLVEQLGGKNTPAVGFAMGLERIVLMLETLELTKDIPATVDVYVTAMGDASKIEAIKIAQSLRSELPHLRVMSHCGGGNFKKQMKRADKSGAQVALVIGEDELANNQVAVKYLREKKEQELVARDALATYIAELI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC16_EMENI
Sequence: MENSNSEASAVWNPALRTDDNHETAATVEEISAPVSSDVAPLTPKATTANTDIVPDAIDSINTESPAREETAELPLNEHTHTVPGAAEPVNVGSAGFIETAEAPPTAIDDPGAVPVAVSPNGETSAPAIATDVTSVSENTVPDVTESSSVEPTALIEIAQAESATGEDFNQAETREEFREEAAELFSAAADENQETDAFKPQAELAAAPGDGYNNLQSMQEEHVQEGQTHQLEIDTSVNAAQGSSDYPTPGWVYQQGIADHATPIDGELRSTNHDLWGSPKSVDNGEDRFFDQLRTQTKPIYFPSEESRFEEGVPLLDGSAEAPVEAAPVEATPVEQAVPQPGQLDRVFEGDEDEDDGFFSSAQQPATENEPQEPVHIQRKSTSQVLDSLNTNRDGVHSPLSPTAEEFNDIIAAAASKSPENVQEPASEEDLAARWQAELSDDDLEVAPVEEDLAAKWQAELDDDDLLLEDEPSDLAQNTAAEVVNGHGVEPNLQALGSPFGTPQNPSKPKPAQSVYTPHQPSTADLVQSVPIPGATPLSSSAPYSTSYFQPRPEPPAPAVRAESFAERPKEGYKSPYDLPEDLAPRRKPATKPVVSSAANVPAPPPRSSSFTAPPPPQSSSGVPVPPINAATLPPASKPNAPVASAPKNFYEELPLPPVRPRSRPAESGRYTPKFNTASPAFVQPPPAAHPVTNPYAQLSGDTPQSQLQQPEKLGPYANNVGSSSQSAPAVPPINSRYSPKPPTLQPGVKPPASPRYSPAPPPPAAASAPLQRYTSQPSVIPGQTVTLPFQPRTSSPLAHHEKVSYQPNEASRKPSFPQPTSPVTGQPSHTETAAPMSPRSSQVQASGPSAVDTSSSYQQTSPPRNPYAPPSYLEEFSRRVSHVNNSTPSAYTPPPETPPFVPPRRSQTQSPTQQQSGPRLSVPSVDPLKRPASVHAPSSPTKTSHTYAPMQPSSHIRTISQSLEFIPPSDGQELDPLQRWKGAPIFKFGFGGTVLSSFPKHVPRYSAGQTAPKIKPMPGDVKTTQLKDVISFPETIVRHPGPLRNKSKKKDLVAWLSSRIAAFENEGVPQNLQAYPDSYKRRDEKILLWKAVRVLVEHDGGMQSTPDLQEALRGILFPHLQTNGLEPMYSDSLQSFGAEVINASSLSDSAESKPLSSIRNNLLIGEREKAVWSAADNRLWGHAMIIASTLDKSIWKQVVQEFVRREVRSNSGNPESLAALYEIFAGNFEESVDELVPPSARAGLQMVSKVDGHGPSKDALAGLESWKDTLGLVLSNRSPEDHRALLALGRLLLSYGRIEAAHICLIFSRAAVFGGPDDPQASIVLLGVDHVHSSPTALLDDDAILLTEAYEYATSVLGASPTSTLPHLLALKLVHAWSLTDQGRKSEAQQYCDAITAALKATTKQSGYHHQHLFFGVDELSARLKQTTGDGGSWISKPSMEKVSSSMWNKFSNFVAGDDSDAASTGSGKGGETGFGPFAQISGTPTVSRSPSVTDLYGQYPMPVAQQVPGAGTSRYQPNNQNAPNSSPDQGRGRSSLDSQRSASFGLSYGQRRGSQEYGHPSESPMYGGGPFYGSPTAGYQSTPPQTSYMPLAPVEEDMAQQAYTPPTATPQGLFGHDLPYQPPAQNPFDQSTGPEAPASQHTEADGYMPPTGNTGYEPPASNTLEVEVTEESEDEKPRKKLTMDDEDDDDIAARAEALKKAEKARKDREADEAFRKAAEADAKKPAPAKSSWWGWIKGGNKEEANSGKPIRAKLGEESSFYYDKELKKWVNKKDPNSATPARATPPPPKAMGPPSRAASGSSMPPSGTAGLGSRPPSVAPPPSGSPAPSSLGLPPTPGLGPARSASTGAVPPAGNASSRPGSSAGPPPRPSTSLSHASSIDDLLGAPQARKGATSRGRKKGRIRDLPHLAYRSVYPCIANYQPPYIVVNLHAISSGSMAWLLVL
What is the function of this protein?
Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules.  Also involved in autophagy (By similarity).
What are the official names of this protein?
COPII coat assembly protein sec16, Protein transport protein sec16.
What is the protein family that this protein belongs to?
Belongs to the SEC16 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NADD_LEGPL
Sequence: MHSIAIFGGTFDPVHNGHIKTSLAIQANFGFDSYYFLPCKSPAIKPPSFASSEQRVEMLKLALKPYPDFKIDTRELDRDTPSYMVYTLQSFRQEYTDSSLTLIIGYDGLLNLPQWYQWEKIISLANLLVINREEFFQKPVPKSVQTLLNQYRNDDKNILLNHHAGSICLYNAGHYDISSTKIREQLKQHKDVKNNLPDLVYDYIKKQELYQ
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: HLYDP_ECOLX
Sequence: MKTWLMGFSEFLLRYKLVWSETWKIRKQLDTPVREKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTESLRER
What is the function of this protein?
Involved in the transport of hemolysin A.
What are the official names of this protein?
Hemolysin secretion protein D, plasmid.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: PAX_I75A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIVVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFVSPKEAKKQLKKDLKSQELCAGLPTKVSRRTSPALRILEPMWMDSNRTAALRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: BTUF_YERPG
Sequence: MMPLGLFPLPRAAAVLLISLLTLPAQAAERVISLSPSTTELAYAAGLGDKLVAVSAYSDYPESAKKLEHVASWQGINVERILALKPDLILAWRGGNPQRPLDQLAALGIPIFYSDPTHIDQIASDLDKLAQYSPHPEQAHQAAEQFRQHVNTLRDRYARSQPKRTFLQFGTQPLFTSSGHTLQSEVVSLCGGENIFADSRVPWPQVSREQVMTRKPQVIVVSGTQSQVDNVSAFWLPQLVVPVIALNEDWFNRASPRILLAAQQLCQQMASIPTPVAESH
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
What are the official names of this protein?
Vitamin B12-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BtuF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RNPA_BORA1
Sequence: MSCATLPAEARLHRPSEFTAALKGRRLARGALFIVSAAPATSAPACARLGLVIAKRYAALATTRNAIKRVLREAFRHRRQALPAQDYVIRLHSKVGPLSLTALKRAARTEADAHFGRIAR
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RS10_PSEA6
Sequence: MPNQRIRIRLKAFDHKLIDQSTAEIVETAKRTGAQVSGPIPLPTRKERYTILTSPHVNKDARDQYEIRTHKRLVDIIEPTDKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ATG22_CRYNB
Sequence: MPPPHVRAWYSYAFAAEVFSSYPSGNIPANHFGTCDGKALQSSDPRGMDRYSFVQSSSMYVKSIAVACQAICIISIGPLADIAYWRKRLLLTFAYSGSLSGILFLLFPPLPYAWTPIMAAILNIVGNATYSTSIVCSNAFLPGLAKEDVDVQKAWEEATSEGLQDGLRDVHEDTDEENTGSVSREDEATHLLPDRLIPAVCAISTQDLALSDPLAKLIEPSNAKKHYESRLSLTTSRLSSTGTAIGFFSGVSVLTLLLIPVTALGGSTFSMRLAIGLSGVWWALFTVPTCIGLPGGAPGHGSDFSASQVKKAWVKIGKMVAPKQIHQLPNLYIFLLAWIFLSDGFHTTTYAAILYASSVLSMSAPKIILVGILVQLAAVVSSVLVPRVQRRLSTTSSKPVTNYKVLLAGVVAAAFIPVYTCAGLVLPFGGLRSEGEMYVLAVWFGLVFGPFLSYSRAVYAELIPPGHESTFFSLFAFTDKSASFIGPAAVGLISDLTGNIRYGFLFLLVMLVVPIPVLGRVAVERGRREAVEWAERSRKEMSDERV
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
What are the official names of this protein?
Autophagy-related protein 22.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Vacuole and punctate structures.
Protein: HIS7_METEP
Sequence: MRTASISRRTAETDVSVSIDLDGTGKATIATGVGFLDHMLELFARHGLFDVTIKVEGDLHVDQHHTTEDAGIALGQAVAQALGDKRGIARYADIHLPMDETLSRIAIDISGRPFLVFRTSFRVEKIGQFDTELVREFFQAFAMNAGITLHVETLYGENAHHIAESIFKGLARSLRKAVAIDPREDGRVPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCRB_ARALY
Sequence: MRNATFFIVFYVFISLVLSNVQDVTAQKNKCMRSEMFPTGPCGNNGEETCKKDFKNIYRTPIQCKCLDKYDFARLCDCRFC
What is the function of this protein?
Involved in self-incompatibility.
What are the official names of this protein?
Defensin-like protein b, S locus cysteine-rich-like protein b.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDC_EDWI9
Sequence: MDSQRNLFLVALLFVSFLIWQAWQTDHNPQPVAQTAGQSISDTASQAVPESGQGKLITVKTDVLALTINTRGGDIEQADLLAYPATLGSDTPFQLLETTPQFVYQAQSGLTGKSGPDNPANGARPLYSANQTSYEMLPGQDELRIPLTYTAANGVIYTKTFVLKRNDYAIAVDYKVKNDSHDALDLTLFGQLKQSVDLPKHRDTGSNNFALHTFRGAAYSSSDDKYQKYSFSDIEDKNLNVQTKGGWVAMLQQYFATAWIPHDSGVNTFYSANLGNGQAAIGYKAPSVSVAPNTEKVLSTTLWVGPELQSDMAAVAPHLDLTVDYGWLWFISQPLFKLLQLIHSFVGNWGFAIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKLQAMRERIGDDKQRMSQEMMALYKTEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLAAPDPFYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSRDKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.