PharMolix/UniProtQA huggingface dataset:
Protein: LSHB_COTJA
Sequence: MGGAQVLLLLTLLGTPLVTHGTPPLVVDPSIGSQLGLGSVLGLDLGSMGGSGRPPCRPINVTVAVEKEECPQCMAVTTTACGGYCRTREPVYRSPLGPPPQSSCTYGALRYERWDLWGCPIGSDPKVILPVALSCRCARCPIATSDCTVQGLGPAFCGAPGGFGGQ
What is the function of this protein?
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
What are the official names of this protein?
Lutropin subunit beta, Lutropin beta chain, Luteinizing hormone subunit beta, LH-B, LSH-B, LSH-beta.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: TGIF2_HUMAN
Sequence: MSDSDLGEDEGLLSLAGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNLSVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDVALPRGSSPSVLAVSVPAPTNVLSLSVCSMPLHSGQGEKPAAPFPRGELESPKPLVTPGSTLTLLTRAEAGSPTGGLFNTPPPTPPEQDKEDFSSFQLLVEVALQRAAEMELQKQQDPSLPLLHTPIPLVSENPQ
What is the function of this protein?
Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins.  Probably represses transcription via the recruitment of histone deacetylase proteins.
What are the official names of this protein?
Homeobox protein TGIF2, 5'-TG-3'-interacting factor 2, TGF-beta-induced transcription factor 2, TGFB-induced factor 2.
What is the protein family that this protein belongs to?
Belongs to the TALE/TGIF homeobox family.
Protein: SECD_ECOLI
Sequence: MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVAASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDSTDTQLRAREALMGVMGDKYVVALNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLREKGIPYTTVRKENNYGLSITFRDAKARDEAIAYLSKRHPDLVISSQGSNQLRAVMSDARLSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINIANIQSRLGNSFRITGINNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNIEQGLEACLAGLLVSILFMIIFYKKFGLIATSALIANLILIVGIMSLLPGATLSMPGIAGIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANITTLIKVIILYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.  The large periplasmic domain is thought to have a base and head domain joined by a hinge; movement of the hinge may be coupled to both proton transport and protein export, with the head domain capturing substrate, and a conformational change preventing backward movement and driving forward movement.  Expression of V. alginolyticus SecD and SecF in E. coli confers Na(+)-dependent protein export, strongly suggesting SecDF functions via cation-coupled protein translocation.
What are the official names of this protein?
Protein translocase subunit SecD, Sec translocon accessory complex subunit SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZW10_PONAB
Sequence: MASFVTEVLAHSGRLEKEDLGARISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSIVLSLLKQLQEFSTAIEEYNCALTEKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKFLSMELTIQKQNILYHLGEEWQKLIVWKFSPSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSKLKSFGQMLLKYILRPLASCPSLHAVIESQPNIVIIRFESIMTNLEYPSPSEVFTKIRLVLEVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSEYLIKNCLVYSIPTNSSKLQQYEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIHNTVKIIPDSKINVPELPTPDEDNKLEVQKVSNTQYNEVMNLEPENTLDQHSFSLPTCRISESVKKLMELAYQTLLEATTSSDQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHHNNCMYIAHHLLTLGHQFRLRLAPILCDGTATFVDLVPGFRRLGTECFLAQMRAQKGELLERLSSARNFSNMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTAISEVIGKITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKWMPFKELMMMLQASLQEIGDRWADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK
What is the function of this protein?
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis.  Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores.  Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Centromere/kinetochore protein zw10 homolog.
What is the protein family that this protein belongs to?
Belongs to the ZW10 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Lipid droplet. Note=Dynamic pattern of localization during the cell cycle. In most cells at interphase, present diffusely in the cytoplasm. In prometaphase, associated with the kinetochore. At metaphase, detected both at the kinetochores and, most prominently, at the spindle, particularly at the spindle poles. In very early anaphase, detected on segregating kinetochores. In late anaphase and telophase, accumulates at the spindle midzone.
Protein: RSMA_LEGPA
Sequence: MRHSPRKRFGQNFLQDKYIINEILRAINPLADDNMLEIGPGLGALTQPLLQKLNRLTAIEIDTDLQNYLTRLPVSQGKLNLIPADALTVDFCQFGPHLRVVGNLPYNISTPLLIYLLKFITCIDDMHFMLQKEVVERIAATHGTKAYGRLSVMLQYHCEVEYLFDVPPEAFEPKPKVDSAIVRLTPYRVSPFESVNTEKLENIVAKAFAMRRKTLTNNLKGIISLSQLNDLGIDGGKRPEQISVAEYVQLAKFISN
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_PEDPA
Sequence: MKKGIHPDYHPVVFQDSATGFKFLSGSTVGSAETIKWEDGNEYPLIRVEITSDSHPFYTGRQKFQQADGTVAKFNKKYGLA
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: PEPA_PENRW
Sequence: MVVFSKVTASLACFSAVVSAAAVPVKSPRQGFSVNQVQKTVTGTRTVNLPGVYANALAKYGATVPANVHAAAVSGSAITTPEENDVEYLTPVKIGESTLNLDFDTGSADLWVFSTELSSAEQSGHDVYDVSSSGKKLTGASWSISYGDGSGASGDVYKDTVTVGGVKATGQAVEAAKKISQQFVQDKSNDGLLGLAFSSINTVSPKPQTTFFDTVKSDLDKPLFAVTLKHGAPGTYDFGYIDKKKFTGSLTYTDVDNSQGFWSFTADSYKVGTGSAGPSIEGIADTGTTLLLLDDGVVSDYYKKVDGAKNNYSAGGYVFPCDADLPDFTVTIGSYDAVVPGKHIKYAPVTTGSSSCFGGIQSNSGIGFSIFGDIFLKSQYVVFDAEGPRLGFAAQA
What is the function of this protein?
Secreted aspartic endopeptidase that allows assimilation of proteinaceous substrates.  The scissile peptide bond is attacked by a nucleophilic water molecule activated by two aspartic residues in the active site.  Shows a broad primary substrate specificity.  Favors hydrophobic residues at the P1 and P1' positions, but can also activate trypsinogen and hydrolyze the B chain of insulin between positions 'Gly-20' and 'Glu-21'.
What are the official names of this protein?
Penicillopepsin-1, Aspartic protease pepA.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENGB_BURCH
Sequence: MAFLLHQARFYTTVNHLRDLPPTVQPEIAFAGRSNAGKSTAINVLCNQKRLAFASKTPGRTQHINYFSVGPAAEPVANLVDLPGYGYAEVPGAAKAHWEMLLSSYLATRSQLCGLILMMDSRRPLTDLDRRMIEWFAPTGKPIHTLLTKCDKLTRQESINALRNTQKGLDAYRDQGVKGKLTVQLFSALKRTGLDEAHELIESWLRPSVADEKSEPVAQ
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ALGE1_AZOVI
Sequence: MDYNVKDFGALGDGVSDDTAAIQAAIDAAHAAGGGTVYLPAGEYRVSGGEEPSDGCLTIKSNVHIVGAGMGETVIKMVDGWTQNVTGMVRSAYGEETSNFGMSDLTLDGNRDNLSAKVDGWFNGYIPGQDGADRDVTLERVEIREMSGYGFDPHEQTINLTIRDSVAHDNSLDGFVADYQVGGVFENNVSYNNDRHGFNIVTSTNDFVLSNNVAYGNGGAGLVVQRGSYDLPHPYDILIDGGAYYDNALEGVQLKMAHDVTLQNAEIYGNGLYGVRVYGAQDVQILDNQIHDNSQNGAYAEVLLQSYDDTAGVSGNFYVTTGTWLEGNVISGSANSTYGIQERADGTDYSSLYANSIDGVQTGAVRLYGANSTVSSQSGSGQQATLEGSAGNDALSGTEAHETLLGQAGDDRLNGDAGNDILDGGAGRDNLTGGAGADTFRFSARTDSYRTDSASFNDLITDFDADEDSIDLSALGFTGLGDGYNGTLLLKTNAEGTRTYLKSYEADAQGRRFEIALDGNFTGLFNDNNLLFDAAPATGTEGSDNLLGTDAGETLLGYGGNDTLNGGAGDDILVGGAGRDSLTGGAGADVFRFDALSDSQRNYTTGDNQADRILDFDPTLDRIDVSALGFTGLGNGRNGTLAVVLNSAGDRTDLKSYDTDANGYSFELSLAGNYQGQLSAEQFVFATSQGGQMTIIEGTDGNDTLQGTEANERLLGLDGRDNLNGGAGDDILDGGAGRDTLTGGTGADTFLFSTRTDSYRTDSASFNDLITDFDPTQDRIDLSGLGFSGFGNGYDGTLLLQVNAAGTRTYLKSFEADANGQRFEIALDGDFSGQLDSGNVIFEPAVFNAKDFGALGDGASDDRPAIQAAIDAAYAAGGGTVYLPAGEYRVSPTGEPGDGCLMLKDGVYLAGDGIGETVIKLIDGSDQKITGMVRSAYGEETSNFGMSDLTLDGNRDNTSGKVDGWFNGYIPGQDGADRNVTIERVEIREMSGYGFDPHEQTINLTIRDSVAHDNGLDGFVADYLVDSVFENNVAYNNDRHGFNIVTSTYDFVMTNNVAYGNGGAGLTIQRGSEDLAQPTDILIDGGAYYDNALEGVLFKMTNNVTLQNAEIYGNGSSGVRLYGTEDVQILDNQIHDNSQNGTYPEVLLQAFDDSQVTGELYETLNTRIEGNLIDASDNANYAVRERDDGSDYTTLVDNDISGGQVASVQLSGAHSSLSGGTVEVPQGTDGNDVLVGSDANDQLYGGAGDDRLDGGAGDDLLDGGAGRDDLTGGTGADTFVFAARTDSYRTDAGVFNDLILDFDASEDRIDLSALGFSGFGDGYNGTLLVQLSSAGTRTYLKSYEEDLEGRRFEVALDGDHTGDLSAANVVFADDGSAAVASSDPAATQLEVVGSSGTQTDQLA
What is the function of this protein?
Converts beta-D-mannuronic acid (M) to alpha-L-guluronic acid (G), producing a polymer with gel-forming capacity, required for the formation of the cyst coat.
What are the official names of this protein?
Mannuronan C5-epimerase AlgE1, Poly(beta-D-mannuronate) C5 epimerase 1.
What is the protein family that this protein belongs to?
Belongs to the D-mannuronate C5-epimerase family.
What are the subcellular locations of this protein?
Secreted. Note=Probably exported via the hemolysin-type secretion pathway.
Protein: CACB2_BOVIN
Sequence: MQCCGLVHRRRARVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEDNDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSTLPVSPTLASNSQGSQGDQRTDRGAPGRSASQAEEEHCPEPVKKAQHRSSTQHHNHRSGTSRGLSRQETLDSETQESRDSAYAEPKEEYSHEHADHYAPHRDHNHREEPHGGGEHRHREPRHRSRDPDREQDHNESNKQRSRHKSKDRYCDKDGEGLSRRRNEAADWNRDVYIRQ
What is the function of this protein?
Beta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current (By similarity).  Plays a role in shifting voltage dependencies of activation and inactivation of the channel.  May modulate G protein inhibition (By similarity).  May contribute to beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force (By similarity).  Involved in membrane targeting of the alpha-1 subunit CACNA1C (By similarity).
What are the official names of this protein?
Voltage-dependent L-type calcium channel subunit beta-2, CAB2, Calcium channel voltage-dependent subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the calcium channel beta subunit family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side.
Protein: IL6_MARMO
Sequence: MKFFSIASLGLLLVVATAFPASELQREDGENSVTRNKPTRASSGKTRRQISYLIKEVFEMRKELCKNDETCIKSHVAVSENNLNLPKMTEKDGCFQTGYNRDDCLVRITSGLLEFQVYLRYIRNKFQEGNNRDRAEHVQSSSKALIEILKQEVKDPNKIVFPSPTANINLLAKLESQNDWQKVMTMQLILSNFEDFLQFTLRAVRKA
What is the function of this protein?
Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability.  Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF.  Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance (By similarity).  'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis.  Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand (By similarity).  Also acts as a myokine (By similarity).  Plays a protective role during liver injury, being required for maintenance of tissue regeneration (By similarity).  Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection (By similarity).  Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration (By similarity).
What are the official names of this protein?
Interleukin-6, IL-6.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL16_HYPNA
Sequence: MLQPKRTKFRKAFKGQINGQSKGGFTLSFGQFGLKALEPERVTARQIEATRRAITREMKRQGKVWIRVFPDVPVTAKPIEVRMGKGKGGVDRWVARVAPGRILFEIDGVPEDIARQALALGAAKLPIKTKVVKRIEGI
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: HISZ_ALKEH
Sequence: MSDSAFSKDNRWLLPEGVDELLPPRAAQMETLRRQLLDQFGAWGYELVMPPFIEYLDSLLTGTGHDLDVQTFKLTDQLTGRLMGVRADITPQVARIDAHRLRREAPSRLCYIGSVLHARPEGISRSRNPVQVGAELFGHAGVESDIEIISLAVASLRTAGVAQPHLDLGHVGIFRGLARAAGCTPAQEGALLEALQRKAVAEIDELLDEAAIDPHLRRMLRALPQLNGGLEALDHAGEVLAEAPQGVRQALRTLWGVAAGLERRLPDLPLHFDLAELRGYGYHTGIVFAALVPGYGSEVARGGRYDDIGRVFGNPRPATGFSADLRTLVQVADGQPAVPAGKGVLAPWGDEPDLIKVIEALRAEGERVVQELPGQQGGAAAQGCDRRLQQDDGGGWVTRPL
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_PHOV8
Sequence: MGKLTKNQKLAAEKIEAGKAYSLKEAAQLVKDITFSKFDASLDIDVRLGVDPRKANQMVRGVVSLPHGTGKQVRVLVLCTPDAEAAAKEAGADYVGLDEYIEKIKGGWTDIDVIITMPSIMGKIGALGRVLGPRGLMPNPKSGTVTMDVAKAVKEVKQGKIDFKVDKSGIVHTSIGKVSFTADQIRDNAKEFIATIIKLKPSSAKGTYIKSIYLSSTMSKGIKIDPKTVEEN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: HMOX1_ORYSJ
Sequence: MAPAAASLTAPNALAATSLPFLHGRKSGGGGVSVHAGAPSPSRAVAVVARRLWGSASSSRRMVVAAATAAEMAPAASGEEGKPFVEEMRAVAMRLHTKDQAKEGEKEPQAPPVARWEPSVDGYLRFLVDSKLVFETLETIVDRAAVPWYAEFRNTGLERSEQLKKDLEWFKEQGHTIPEPSAPGTTYASYLEELAEKDSQAFICHFYNVYFAHTAGGRMIGKKVSENILNKKELEFYKWEGNLSQLLQNVRNKLNEVASSWTREEKDHCLDETEKSFSYSGDLLRHIFT
What is the function of this protein?
Catalyzes the opening of the heme ring to form the open-chain tetrapyrrole biliverdin IX with the release of iron and carbon monoxide (CO).  Is a key enzyme in the synthesis of the chromophore of the phytochrome family of plant photoreceptors.  Essential for photoperiod response and repression of flowering through cytochromes that inhibit flowering by affecting both HD1 and EHD1 flowering pathways.
What are the official names of this protein?
Heme oxygenase 1, chloroplastic, Protein PHOTOPERIODIC SENSITIVITY 5.
What is the protein family that this protein belongs to?
Belongs to the heme oxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: 1FEH_HORVU
Sequence: MAQAWAFLLLPALALASYASHLLLPAYITTPLCGGGDGARSFFLCAQAPKDQDQDPSPASTMYKTAFHFQPAKNWMNDPSGPMYFNGIYHEFYQYNLNGPIFGDIVWGHSVSTDLVNWIGLEPALVRDTPSDIDGCWTGSVTILPGGKPVIIYTGGNIDQHQTQNIAFPKNRSDPYLREWIKAANNPVLRPDEPGMNVIEFRDPTTGWIGPDGHWRMAVGGELNGYSAALLYKSEDFLNWTKVDHPPYSHNGSNMWECPDFFAALPGNNGGLDLSAAIPQGAKHALKMSVDSVDKYMIGVYDLQRDAFVPDNVVDDRRLWLRMDYGTFYASKSFFDSKKGRRIVWGWSGETDSPSDDLAKGWAGLHTIPRTIWLAADGKQLLQWPVEEIESLRTNEINHQGLELNKGDLFEIKEVDAFQADVEIDFELASIDEAEPFDPSWLLDPEKHCGEAGASVPGGIGPFGLVILASDNMDEHTEVYFRVYKSQEKYMVLMCSDLRRSSLRPGLEKPAYGGFFEFDLAKERKISLRTLIDRSAVESFGGGGRVCITSRVYPAVLANVGRAHIYAFNNGNAMVRVPQLSAWTMRKAQVNVEKGWSAI
What is the function of this protein?
Hydrolyzes inulin-type beta-(2,1)-fructans.  May play a role as a beta-(2,1)-trimmer during graminan biosynthesis (By similarity).
What are the official names of this protein?
Fructan 1-exohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
Protein: VIF_HV2KR
Sequence: MEEGERWIVVPTWRVPGRMEKWHSLVKYLKHRTKDLEGVCYVPHHKVGWAWWTCSRVIFPLQGNSHLEIQAYWNLTPEKGWLSSYAVRITWYTERFWTDVTPDCADSLIHSTYFSCFTAGEVRRAIRGEKLLSCCNYPQAHRSKVPLLQFLALVVVQQNGRPQKNSTTRKRWRSNYWRGFRLARKDGRGHKQRGSEPPASGAYFPGVAKVLEILA
What is the function of this protein?
Counteracts the innate antiviral activity of APOBEC3G.  Forms a complex with host APOBEC3G thus preventing the entry of this lethally hypermutating enzyme into progeny virions.  Functions as an adapter molecule, recruiting APOBEC3G to the ubiquitin-proteasome machinery.  Targets APOBEC3G for degradation through the assembly with elongin BC complex, CUL5 and RBX1.  Binds viral RNA and affects the stability of viral nucleoprotein core.  May play a role in viral morphology (By similarity).
What are the official names of this protein?
Virion infectivity factor, Vif, Q protein, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor (By similarity).
Protein: SSPO_ANOFW
Sequence: MVKRKANHVIPGMNDASAQGKGAGYNEELSNEPLTEAQKQNNKKRKKNQ
What are the official names of this protein?
Small, acid-soluble spore protein O, SASP O.
What is the protein family that this protein belongs to?
Belongs to the SspO family.
What are the subcellular locations of this protein?
Spore core.
Protein: NADD_MARSD
Sequence: MKIGLFGGSFNPVHLTHLDVANGVLKRLGLDKVLFVPAGNPYHKEQGEMLSAELRYELVKKAVQGCSGLGVSDIDISADGPTYTVDTLREASRRYPDAELYFIMGQDSLETFTTWKGWQSIPELANVVAVSRAEADHGAMSQELKRIFPEVVESGQDVWQMKGGKSIYIIGDFDFVISSTLVREEWKKGRDVSKLVPKAVAECMNEKGDKLKKFWR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: NSAR_DEIRA
Sequence: MAHTGRMFKIEAAEIVVARLPLKFRFETSFGVQTHKVVPLLILHGEGVQGVAEGTMEARPMYREETIAGALDLLRGTFLPAILGQTFANPEAVADALGSYRGNRMARAMVEMAAWDLWARTLGVPLGTLLGGHKEQVEVGVSLGIQAGEQATVDLVRKHVEQGYRRIKLKIKPGWDVQPVRATREAFPDIRLTVDANSAYTLADAGRLRQLDEYDLTYIEQPLAWDDLVDHAELARRIRTPLCLDESVASAADARKALALGAGGVINLKVARVGGHAESRRVHDVAQSFGAPVWCGGMLESGIGRAHNIHLSTLPNFRLPGDTSSASRYWERDLIQEPLEAVDGLMPVPQGPGTGVTLDREFLATVTEAQEEHRA
What is the function of this protein?
Acts as a N-succinylamino acid racemase (NSAR) that catalyzes the racemization of N-succinyl-L-phenylglycine and N-succinyl-D/L-phenylalanine (PubMed:24872444, PubMed:25875730).  Can catalyze the racemization of a broad range of N-acylamino acids, including N-acetyl-D/L-methionine, N-acetyl-D/L-phenylalanine, N-acetyl-L-glutamine, N-acetyl-L-tryptophan, N-acetyl-L-leucine, N-formyl-D-methionine, N-formyl-D-norleucine, N-carbamoyl-D-methionine and N-carbamoyl-D-norleucine (PubMed:15313614, PubMed:16650857, PubMed:25875730).  Also converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24872444).  Catalyzes both N-succinylamino acid racemization and OSB synthesis at equivalent rates (PubMed:24872444).  However, NSAR activity is probably the protein's biological function, because menaquinone biosynthesis genes are missing in this species (Probable).
What are the official names of this protein?
N-succinylamino acid racemase, NSAAR, NSAR, N-acylamino acid racemase, NAAAR, o-succinylbenzoate synthase, OSB synthase, OSBS.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
Protein: DFP4_LONON
Sequence: MYGMSVRILMMSSLSACMLVSTVTAWDFLKELEGVGQRVRDSIISAGPAIDVLKKSQGPRRWSRP
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Defense protein 4, DFP-4.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YHEO_SHIFL
Sequence: MSRSLLTNETSELDLLDQRPFDQTDFDILKSYEAVVDGLAMLIGSHCEIVLHSLQDLKCSAIRIANGEHTGRKIGSPITDLALRMLHDMTGADSSVSKCYFTRAKSGVLMKSLTIAIRNREQRVIGLLCINMNLDVPFSQIMSTFVPPETPDVGSSVNFASSVEDLVTQTLEFTIEEVNADRNVSNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNISKHTVYLYIRQFKSGDFQGQDK
What are the official names of this protein?
Uncharacterized protein YheO.
What is the protein family that this protein belongs to?
To H.influenzae HI_0575.
Protein: Y672_METM7
Sequence: MYVPEEIIETIKMIEYQNLDIRTTTLGVNLKDCADKDLDLLKENIYNKITSFGGNLVETANKVSQKYGIPIVNKRISVTPIGLIMGSTLKGLSNEEAIDACVEVGITLDNIAKEVGVDFIGGYSALVQKRATPEEKMLIRSIPKLMTKTDRVCASVNVATTKAGINMYAVKKMGEIVKETAEITKDAIGCAKIVVFCNAPEDNPFMAGAFHGPGEGDAVINAGVSGPGVVRAVVEQLKGKDIGTVSDEIKKTAFKITRMGELVGKEVASELGIDFGIVDLSLAPTPAIGDSIANILEAVGLERCGTHGTTAALAMLNDAVKKGGAMASSNVGGLSGAFIPVSEDAGMIEAVEVGALRLEKLEAMTCVCSVGLDMIAVPGKTPASTLSAIMADEMAIGMINKKTTAVRIIPVPGKDVGDSVEYGGLLGTAPIMPVSEFSSEEFIERGGRIPAPIQSLTN
What are the official names of this protein?
UPF0210 protein MmarC7_0672.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: FXSA_SERMA
Sequence: MRWLPLLLIFLLAYIEISIFIKVAAVLGVAVTLLLVVFSSCVGISLVRNQGMKTFVQMQQKLAAGESPAAEMVKSVSLVLAGFLLLIPGFFTDFLGLLLLLPPVQKSLTLKLMPHLSVYRPGGWTGGDAANGNTFDGEF
What are the official names of this protein?
UPF0716 protein FxsA, Suppressor of F exclusion of phage T7.
What is the protein family that this protein belongs to?
Belongs to the UPF0716 (FxsA) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APGM_METBF
Sequence: MKYAVLIGDGMADYPIDKLGGKTILQAAQTPAMDYIAAHGKIGLAKTIPDGLPAGSDVANMSILGYDPAVYYSGRAPLEAASMGVALASDDVAFRCNLVTIEHGRIKDYSAGHISSEEARILIETLDAELGNEELSFYPGISYRHLLIAKDNLGAETECTPPHDITGKKIEEYLPGGKEGDFFSDLIKKSMIVLELHPVNLRRIEEGKNPANSIWVWGQGSAPKFTPFRELYEKTGAVISAVDLLKGIGVYAGMDVIEVQGATGYLDTNYEGKASAAIEVLKTRDLVFVHVEAPDEAGHEGSIDKKLKAVEDFDSRIVAPILKHAKTSDEPFTILVLPDHPTPISIKTHARDPVPFAVYRTDKTDSDSAEAFDEESAKKGSLGLVKASDLIGILVKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, aPGAM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.