PharMolix/UniProtQA huggingface dataset:
Protein: TRAP_BGYMJ
Sequence: MESRFKLKEEYHQSCCAIQVRVPVIKTSSTKRKTELYTTGPFIMRSSSPSQPPSIKAQHRIAKHKAIRRRRIDLNCGCSIFYHIKCADHGFTHRGEHHCASGREFRFYLGGTKSPLFQDHAGGRSSIHTDKDIPHPSQVQSQPQESTGSPQSIPELPSLDDIDSSFWDDIFK
What is the function of this protein?
Strong activator of the late viral genes promoters.  Enhances the expression of the capsid protein and nuclear shuttle protein.  Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.  Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway.  Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense.  Determines pathogenicity (By similarity).
What are the official names of this protein?
Transcriptional activator protein, TrAP, 19.6 kDa protein, Protein AC2, Protein AL2.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae transcriptional activator protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=The phosphorylated form appears to accumulate almost exclusively in the nucleus, whereas the non-phosphorylated form is found in both nucleus and cytoplasm.
Protein: RL333_STRPC
Sequence: MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVVFTEVK
What are the official names of this protein?
50S ribosomal protein L33 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RS8_ACISJ
Sequence: MSMSDPIADLLTRIRNAQMVSKATVSVPSSKVKVAIAQVLKDEGYIDGFEVKSESGKTELEITLKYYAGRPVIERIERVSRPGLRVYKGCGSIPQVMNGLGVAIVTTPKGVMTDRKARATGVGGEVLCYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CYSZ_ECODH
Sequence: MVSSFTSAPRSGFYYFAQGWKLVSQPGIRRFVILPLLVNILLMGGAFWWLFTQLDVWIPTLMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAPFNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFAWYLPRAIVLLILYFIPGIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSLFTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR
What is the function of this protein?
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake.  Provides the sulfur source for the cysteine synthesis pathway.
What are the official names of this protein?
Sulfate transporter CysZ.
What is the protein family that this protein belongs to?
Belongs to the CysZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PANC_SALCH
Sequence: MLIIETLPLLRQHIRRLRQEGKRVALVPTMGNLHDGHMKLVDEAKARADVVIVSIFVNPMQFDRPDDLVRYPRTLQEDCEKLNKRKVDYVFAPAVEEIYPQGLEGQTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLIQPDIACFGEKDFQQLALIRKMVADMSYDIEIVGVPIIRAKDGLALSSRNAYLTAEQRKIAPGLYNVMNSIAEKLIAGNRELQEIIAIAEQELNEKGFRADDIQIRDADTLQELTETSKRAVILAAAWLGQARLIDNQSVTLAQ
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JOIN_SOLLC
Sequence: MAREKIQIKKIDNSTARQVTFSKRRRGLFKKAEELSVLCDADVALIIFSSTGKLFDYSSSSMKQILERRDLHSKNLEKLDQPSLELQLVENSNYSRLSKEISEKSHRLRQMRGEELQGLNIEELQQLERSLETGLSRVIERKGDKIMREINQLQQKGMHLMEENEKLRQQVMEISNNNNNNNNGYREAGVVIFEPENGFNNNNNEDGQSSESVTNPCNSIDPPPQDDDSSDTSLKLGLATLLRLKRSKARCGYFCMLLEEGEKKK
What is the function of this protein?
Putative transcription factor that coordinates gene expression underlying the differentiation of the pedicel abscission zone.  May also be involved in the maintenance of the inflorescence meristem state.
What are the official names of this protein?
MADS-box protein JOINTLESS, LeMADS.
What are the subcellular locations of this protein?
Nucleus.
Protein: RRF_STRPN
Sequence: MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEYYGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDIGITPANDGSVIRLVIPALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKREKAKEITEDELKTLEKDIQKVTDDAVKHIDDMTANKEKELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_GEOSL
Sequence: MTTRTISPEKTDDDYVESSLRPRALEDYIGQEKAKGNLRVFIDAARKRGEALDHVLLYGPPGLGKTTLANIIACEMGVNIKSTSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVEEILYPAMEDFQLDIIIGQGPSARTIKLDLPRFTLVGATTRAGLLSSPLRDRFGVISRLEFYTDAELSTIVTRSAHILDIQIEPDGARELARRSRGTPRIANRLLRRVRDFAQVRADGVISAQVVDESLKLLEIDEKGFDQMDRTIMLTIIDKFGGGPVGLDTIAAAIGEERDTIEDVYEPFLIQHGFINRTPRGRVATKSAYEHFGRIAPAPGQGALF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GCSPB_BACLD
Sequence: MNNQDQSLIFEVSKEGRVGYSLPELDVPETDVTDVIDEAYIRDEPADLPEVSELDIMRHYTALSRRNHGVDSGFYPLGSCTMKYNPKINEKIARIPGFSAIHPLQDEATVQGALELLYDLSEHLEEITGMDEVTLQPAAGAHGEWTGLMMIRAFHEANGDHKRTKVIVPDSAHGTNPASATVAGFETVTVKSNDDGLVDLEDLKRVVDEETAALMLTNPNTLGLFEENILEMAEIVHSAGGKLYYDGANLNAVLSKARPGDMGFDVVHLNLHKTFTGPHGGGGPGSGPVGVKKELIPYLPKPVLVKKDGRYTFDHDRPHSIGRVKPYYGNFGINVRAYTYIRSMGPDGLKEVTENAVLNANYMMRKLAPYYDLPFDRHSKHEFVLSGRRQKKLGVRTLDIAKRLLDFGFHPPTIYFPLNVEECIMIEPTETESKETLDAFIDTMIQIAKEAEETPEVVQEAPHTTVVKRMDETKAARKPVLRYEK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: STXB3_HUMAN
Sequence: MAPPVAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVENIYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFNKIKASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIKDIMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGITYSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSLIKDE
What is the function of this protein?
Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
What are the official names of this protein?
Syntaxin-binding protein 3, Platelet Sec1 protein, PSP, Protein unc-18 homolog 3, Unc18-3, Protein unc-18 homolog C, Unc-18C.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane. Note=In platelets, predominantly cytosolic. Low amounts membrane-associated.
Protein: EUTL_SALTY
Sequence: MPALDLIRPSVTAMRVIASVNDGFARELKLPPHIRSLGLITADSDDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDAMVASIENGAAFQWANDAENTAFLAHVVSRTGSYLSSTAGIALGDPMAYLVAPPLEATFGIDAAMKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLDIARNPVQRA
What is the function of this protein?
Expression of the eut operon allows this bacteria to use ethanolamine as a carbon, nitrogen and energy source.  It relies on cobalamin (vitamin B12) both as a cofactor for the ethanolamine ammonia-lyase (EAL) activity and to induce the operon (PubMed:3045078).  EA enhances bacterial survival in macrophages in a concentration-dependent manner, suggesting it is an important nutrient during infection (PubMed:29531136).
What are the official names of this protein?
Bacterial microcompartment shell protein EutL, BMC-T, Ethanolamine utilization protein EutL.
What is the protein family that this protein belongs to?
Belongs to the EutL/PduB family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: RS17_ANAD2
Sequence: MERGNRKSRIGVVVSNKMTKTVVVKVERRVADPKYGKIVTKAEKYKAHDEDQACQIGDRVRIVETRPISKDKRWRVAETIEKAEA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ARGJ_THEFY
Sequence: MSVTAPLGFRAAGVAAGIKDGGQRDVAVVINDGPHHSAAAVFTKNRVKAAPVQWSQQAVADGQVRAVVLNSGGANACTGAAGFQDARTTAEHLAAALNDSADRIVVCSTGLIGERLPMPKLLAGVDAAVAEAARDGGLNAADAIRTTDTVSKIAFRRGSGYTIGGMAKGAGMLAPSLATMLSVLTTDAVLTPEQCTALLRAATEVTFDRLDTDGCTSTNDTVVLMASGASGTTPDEAEFSRLLTEVCQDLCRQLLADAEGATKAIAIEVVGAASTDDAVTVGRAIARNALFKCAIYGEDPNWGRVLAAVGTTDAVFEPDNINVAINGVWVCRGGSVGDDRAKVNLKPRDVTVTVDLSAGSASATVWTTDLTVDYVHENSAYST
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_SACEN
Sequence: MRLVFAGTPEPAVPSLRALIESANHEVAAVVTRPDAPAGRGRKLMRSPVGALADEHGIEVLTPAKASDPEFLARLRELEPECCPVVAYGALLRQTALDIPEHGWVNLHFSLLPAWRGAAPVQAAIKHGDQITGASTFRLVPELDAGPVYGVVTEEVRDTDTSGVLLERLSVSGAKLLVATLDGIADGTLRAEEQPADGVSYAPKVEVEDARVDFTAPARAVDRLVRSVTPDPGAWASFRDERLKLGPVSIVDEDLGLAPGEIRVERRRVLAGTGSAPVALGEVQAQGKKRMAATDWARGSRIEQGERLK
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RT25_ASHGO
Sequence: MKIQTNAVNVLDRTSFYLQAGLLKKTPAWYNVVARIPPVTKFAREPKLHDPVSGKYKGELDIMTDRLNRNTETYKTRAGSSDRQTAAVHKPSKLRFIEDKLRSLFFQQHPWELSRPKVLVENMGNEQYDWSRMLQLGKPLDGESVVQRTLYLLKSGAHREMLAAYDQARFEFYRLRMQQELEEQIAYEEATMVGAVFKTTAVEHGLQQEQKVLDKWKEDVVAGLQLMSAKKNSTKQSWAEATEEKEEQDSAEPEELKL
What are the official names of this protein?
37S ribosomal protein S25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SNX4_NEUCR
Sequence: MAVIDQDNFSNISWHSEQNAESAASTAQVHHESNSSPEYARSGPDDGRPGDNAAGMEHDELDHSGGEILDCTVSDPHKENDGTKDAYVSYLITTNTTFPSFQKPKTTVRRRFTDFVFLYKVLCRDYQACAVPPLPDKQRMEYVRGDRFGTDFTARRAYSLQRFLARLALHPILRKADILHAFLESPDWNATMRSRSVRGSLASPGGIGDSTLGGSAAAGGGGGVFDTFADSFMNAFTKVHKPDRRFIEIKEKSDKLDEDLNHIEKVVARVARREADIESDLKDLAEQFQKLITLEPGVETAVRAFAASVEDTASGLKKLKDHTDQDYLGSLRDMVAYSGTLKNLLKAREQKQLDYEQLTEYLNKSRTDRDMLASGQSYGAGSALMSGAGGFIRSKIEDVRGVDHEQARRDRQRKLELRIEELTREVEVARNESESFAEQVSREVESFDWIKRVEFKRQFSGLADAHIEFYGDVMSVWEQYVMEMEKEGVVLPA
What is the function of this protein?
Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells.  Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), mitophagy, and pexophagy (By similarity).
What are the official names of this protein?
Sorting nexin-4, Autophagy-related protein 24, Vacuolar sorting protein 5.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Endosome and other perivacuolar punctate structures.
Protein: FLIE_TREDE
Sequence: MVNAVNVANVNSVPGLLDVPKINAVVTDNFRAKMVSNTDMIELAANKEAASFEQTILKAFDSMNAKQTNMDKLGEQMIVDPESVDVHDITMGMAEASLSLKLAQTIIDRLVKTWNDITTTR
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: RLMN_PARXL
Sequence: MTSSPTVNLLDLDAQGLVAYCDSLGEKPFRARQLQRWIHQYNAADFDGMTDLAKSLREKLKGRATISMPGIVSDHISTDGTRKWLIDVGNSNAVETVYIPEETRGTLCVSSQAGCAVNCRFCSTGKQGFSRNLTTGEIIGQLRMAEFALRASRGVDGGRATGGDGKGERVVTNVVMMGMGEPLLNYDAVVPAMRLMLDDNAYGLSRRRVTLSTSGVVPMMDRLGADLPVALAVSLHAPSDPLRDMLVPLNKKYPLRELMAACQRYLKVAPRDFITFEYCMLDGVNDSEAQARELLAVTRDVPCKFNLIPFNPFPESGLIRSKPEQIKRFAQVLMDAGVITTVRKTRGDDIDAACGQLAGAVKDRTRLAERTGKAAKIIEVRAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRIM2_MOUSE
Sequence: MASEGASIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNGEDSSILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTTEGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFRVGTKGRNKGEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSNDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ
What is the function of this protein?
UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11.  Plays a neuroprotective function.  May play a role in neuronal rapid ischemic tolerance.  Plays a role in antiviral immunity and limits new world arenavirus infection independently of its ubiquitin ligase activity by decreasing virus internalization (PubMed:30726215).
What are the official names of this protein?
Tripartite motif-containing protein 2, E3 ubiquitin-protein ligase TRIM2, Neural activity-related RING finger protein, RING-type E3 ubiquitin transferase TRIM2.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_GLUDA
Sequence: MTQFTKLEASSRAKAGKGAARATRRDGQVPAVIYGAKQEPTLVALDPRLVVREMQRGGWRSRVYDVTVDGASSPALMREIQLHPVSDKPIHVDFQRLAAGERVHVEVRIVFTGEDKSPGIKRGGVLNIVRHTVEVSADPANIPESFTVDLSQLDIHDNVRWDDLQGTGSVTPTLQIPNFVIATVAAPSADETPEPAAAPAAAPAKK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: RNH2_STRA3
Sequence: MATIKEIKAILETIVDLKDKRWQEYQTDSRAGVQKAILQRKKNIQSDLDEEARLEQMLVYEKKLYIEHINLIAGIDEVGRGPLAGPVVAAAVILPPNCKIKHLNDSKKIPKKKHQEIYQNILDQALAVGIGIQDSQCIDDINIYEATKHAMIDAVSHLSVAPEHLLIDAMVLDLSIPQTKIIKGDANSLSIAAASIVAKVTRDKIMSDYDSTYPGYAFSKNAGYGTKEHLEGLQKYGITPIHRKSFEPIKSML
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGP_RAT
Sequence: MAEAEAGGDEVRCVRLSAERAKLLLAEVDTLLFDCDGVLWRGETAVPGAPETLRALRARGKRLGFITNNSSKTRTAYAEKLRRLGFGGPMGPEAGLEVFGTAYCSALYLRQRLAGVPDPKAYVLGSPALAAELEAVGVTSVGVGPDVLHGDGPSDWLAVPLEPDVRAVVVGFDPHFSYMKLTKAVRYLQQPDCLLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPERTVMVGDRLDTDILLGSTCSLKTILTLTGVSSLEDVKSNQESDCMFKKKMVPDFYVDSIADLLPALQG
What is the function of this protein?
Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol (PubMed:26755581).  Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism.  Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity.  However, their physiological relevance is unclear (By similarity).  In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity).
What are the official names of this protein?
Glycerol-3-phosphate phosphatase, G3PP, Aspartate-based ubiquitous Mg(2+)-dependent phosphatase, AUM, Phosphoglycolate phosphatase, PGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: MEND_SHESA
Sequence: MRTENTATLNLMWGALILEELARLGVQHVCMAPGSRSTPLTLAAAQQTKLKRHLHFDERGLGFMALGLAKASCAPVAIITTSGTAVANLYPAIVEAWLTHVPLIVLSGDRPPELLGCGANQAIVQPAIFANYAQQVNLPTPDAHIAPQMLLTTLDEAVANQTRPVHINCMYREPLYPSEMSGTILDSESPYLRPLQTWLQHAKPYTQYGKSEQLSSPSDDAIMRFVHGKGVIIAGTLTPEQDPQQLIALSQKIGWPLLTDAQSQLRQHPAAIGNIDQLLQHPKARNLLQEADRVLVFGGRLLSKRLIAYLAEQNWHSYWQVLPQQDRLDPSHNAKHIWHANAAQFAQLNWYRSSSANWANTLVTYNDELHSLFVRNIDQGEFGEAQVIRAIANTRPLEQQLFIGNSLPVRLYDMYAPVSCCTATTYTNRGASGIDGLLATACGIAAHQGKPTSLIIGDLSQLHDLNSFAIARSLTSPLVIIILNNDGGNIFNLLPVPNEELRSDYYRLSHGLEFGYAAAMFNLPYNQVDNLADFQSCYHEALDYQGASVIEVSVSQHQASEQIAALNLWVKQS
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RL20_CORGL
Sequence: MARVKRSVNAKKKRREILKSAKGYRGQRSRLYRKAKEQWLHSMTYSYRDRRARKSEFRKLWIQRINAAARMNGITYNRLIQGLRLAEIEVDRKILADLAVNDFATFSAICEAAKAALPEDVNAPKAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RL6_MICLU
Sequence: MSRIGRLPITIPAGVDVTIDGDRVSVKGPKGPKGQLEHSLPTPITATLEEGQVTVARPDDERESRSLHGLTRTLISNMVEGVTNGFSKQLEVVGTGYRVQAKGQDLEFDLGYSHPVPVKVSQGITFTVEGNRVTVAGIDKQQQVGETAANIRKLRRPDPYKGKGVYAGEQIRRKAGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ROB1_AGRRH
Sequence: MDPKLLFLPRFQPVDLTPAWSQINLFEGIRFAFAIYSRDYSKPLLHFQKRWALAVLDLKENSPPIYILKQLAELLKNKVCYHPPMFVSQPDLARENDQHVFVYLSREKMQKVLKEQSITFGMEAVLATTIQPYRSELALQEMLRVHNLAWPHSRTEEPDLECFIAIFASSLFIHLLELKVTNVYGREVACTFFLRRGTENRPYDVVACGTTQFTKNALGISRPAASSPEPDLTLRLSGPDQEGEEGVMKPAAVNLKKEA
What is the function of this protein?
Induces differentiation and growth of neoplastic roots (hairy roots).  Seems to function as a tyrosine phosphatase.
What are the official names of this protein?
Protein-tyrosine phosphatase RolB, ROL B protein.
Protein: NRDR_JANSC
Sequence: MRCPFCGNVDTQVKDSRPAEDHVAIRRRRFCPACAGRFTTYERVQLRDLVVIKSNGKREDFDRTKLERSIRMALQKRPIEPERVDQMISGMVRRLESLGETDVQSKVIGEIVMERLAAIDTVAYVRFASVYKNFQATGDFEDFLSELRPPAPTTDT
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: MCH_METRU
Sequence: SLSHGKYYALGSGPARAMATKVKDGAVEPVEELYKELEYRDSHDKTVLVIENDAVPPVEIVEKVAAACGVSPADLTIIVTPTSSLAGGVQVVGRVLEVAMHKAHALHFPLENIVDGTGSAPVCPPHPNFVKA
What is the function of this protein?
Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
What are the official names of this protein?
Methenyltetrahydromethanopterin cyclohydrolase, Methenyl-H4MPT cyclohydrolase.
What is the protein family that this protein belongs to?
Belongs to the MCH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YICS_ECOL5
Sequence: MKPTMLLMITVFLIFPAISQAESPFSSLQSAKEKTTVLQDLRKICTPQASLSDEAWEKLMLSDENNKQHIREAIVAMERNNQSNYWEALGKVECPDM
What are the official names of this protein?
Uncharacterized protein YicS.