PharMolix/UniProtQA huggingface dataset:
Protein: PIGL_HUMAN
Sequence: MEAMWLLCVALAVLAWGFLWVWDSSERMKSREQGGRLGAESRTLLVIAHPDDEAMFFAPTVLGLARLRHWVYLLCFSAGNYYNQGETRKKELLQSCDVLGIPLSSVMIIDNRDFPDDPGMQWDTEHVARVLLQHIEVNGINLVVTFDAGGVSGHSNHIALYAAVRALHSEGKLPKGCSVLTLQSVNVLRKYISLLDLPLSLLHTQDVLFVLNSKEVAQAKKAMSCHRSQLLWFRRLYIIFSRYMRINSLSFL
What is the function of this protein?
Involved in the second step of GPI biosynthesis.  De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.
What are the official names of this protein?
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, Phosphatidylinositol-glycan biosynthesis class L protein, PIG-L.
What is the protein family that this protein belongs to?
Belongs to the PIGL family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: TRHO_RHOJR
Sequence: MAVPKIVLFYVFTPLADPEAIRLWQYTLAEANNLTGRILVSEHGINATVGGDIRDVKRYVKGTRSYAPFKDADIKWSDGLGDDFPRLSVKVRPEIVTFGAPGELKVDADGVVGGGTHLAPDEVHRLVEGRGDDVVFFDGRNGFEAEIGRFRDAVVPDVSTTREFVHELDSGKYDHLKDKAVVTYCTGGVRCEVLSSLMRSRGFGEVYQLDGGIVRYGEAFGDTGLWEGSLYVFDKRMSIEFSDQAKTLGRCSTCGGPTSRYENMPDDRGRELVLVCADCTENRAG
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: FNR_ECO57
Sequence: MIPEKRIIRRIQSGGCAIHCQDCSISQLCIPFTLNEHELDQLDNIIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSYTITEQGDEQITGFHLAGDLVGFDAIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILLLSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSGMLAVKGKYITIENNDALAQLAGHTRNVA
What is the function of this protein?
Global transcription factor that controls the expression of over 100 target genes in response to anoxia.  It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metabolism.  When the terminal electron acceptor, O(2), is no longer available, it represses the synthesis of enzymes involved in aerobic respiration and increases the synthesis of enzymes required for anaerobic respiration (By similarity).
What are the official names of this protein?
Fumarate and nitrate reduction regulatory protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOTO_XENLA
Sequence: MLHSPVFPAFGHHLAQHPAMPLAMELPRTPKASFNIDSILSRTDRPASKLSMEMPSWQPPSPPSMPYRYSYGMMPYPPVWLIKPTVGYPNMAQQQPMRMPRGECLCPDPTCKERVLPFSHCPNGAMNPLSWRTGPCKMKRIRTVFTPEQLEKLEKEFLKQQYMVGTERVDLASTLNLTETQVKVWFQNRRIKWRKQSLEQKKAKLSQFGVIPADSSDHTDDSRETEEDEDDLDVEL
What is the function of this protein?
Transcriptional repressor.  Plays a fundamental role in notochord formation, acting within the mesodermal region.
What are the official names of this protein?
Homeobox protein notochord, Xnot.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL25_MARMS
Sequence: MSLSINAVARTQEGKGASRRLRNEGLVPAVIYGGETAPVSISFKDNELLKAVGTPGFLTGLVEVTVEGKTEQVLVKALQRHPSTGAVMHMDLQRAQADKAITTRVPLSFINAAQSEGVSKQGGRLTVESKLAEVRCLPANLPEVLTVDVIKGQLDQIFHLSDVILPEGVELVSLLKGEDHDQPIARIGKSKR
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: QUEA_THET2
Sequence: MEGLEAYDYHLPPEQIAQEGVEPRDMARLMVVYREGPFRVAHKRVRDLPEFLRPGDVLVFNESKVIPARLLARKPTGGKVEILLVRERSPGLWEALLGPARKAPPGTRLLLLSPKDLAPVPGLQAEVVAVEEDGVRLLRFQGDLVAHLEEVGEVPLPPYIKAKIPMERYQTVYARRPGSVAAPTAGLHFTPELLERLREMGVELRFLTLHVGPGTFRPVKGDPEKHEMHAEPYAIPEEVAEAVNRAKAEGRRVVAVGTTVVRALESAYREGVGVVAGEGETRLFIRPPYTFKVVDALFTNFHLPRSTLLMLVAAFLGRERTLEAYRLAVAEGYRFYSLGDAMLIL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: I18RA_HUMAN
Sequence: MLCLGWIFLWLVAGERIKGFNISGCSTKKLLWTYSTRSEEEFVLFCDLPEPQKSHFCHRNRLSPKQVPEHLPFMGSNDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSCQSDAQSPAVTWYKNGKLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVLLYILLGTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSFPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNYVNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPHLVKKALRVLPTVTWRGLKSVPPNSRFWAKMRYHMPVKNSQGFTWNQLRITSRIFQWKGLSRTETTGRSSQPKEW
What is the function of this protein?
Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation (PubMed:9792649, PubMed:14528293, PubMed:25500532).  May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).
What are the official names of this protein?
Interleukin-18 receptor accessory protein, IL-18 receptor accessory protein, IL-18RAcP, Accessory protein-like, AcPL, CD218 antigen-like family member B, CDw218b, IL-1R accessory protein-like, IL-1RAcPL, Interleukin-1 receptor 7, IL-1R-7, IL-1R7, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor beta, IL-18R-beta, IL-18Rbeta.
What is the protein family that this protein belongs to?
Belongs to the interleukin-1 receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RS20_XENLA
Sequence: MAFKDPGKAPVDQEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA
What is the function of this protein?
Component of the small ribosomal subunit (By similarity).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (By similarity).
What are the official names of this protein?
40S ribosomal protein S20, S22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_PHEZH
Sequence: MTGQTAPAAPEDANVLGLPETKVRKFNINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLMEARPYAQTIPYFDRLDYVAPMNQEHAYCLAIEKLLGVEVPVRGLLIRTLYDEIGRILNHLLNVTTQAMDVGALTPPLWGFEEREKLMIFYERASGARLHANYYRVGGVRQDLPPELVQDISDWCDAFPKILDDIEGLITDNRIFKQRNVDIGVVTKEEAIAWGFSGVMVRGSGIPWDLRRSQPYALYSEMEFDIPLGVNGDCYDRYLCRMQEMRESTKIMKQCCERLLKTSGPVLVDDHKVSPPRRGEMKRSMEALIHHFKLYTEGYRTPPGDVYACVEAPKGEFGVYLVSNGTNKPYRCKIRAPGYPHLQAMDWMNRGHMLADVSAILGSLDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DNJB6_CHICK
Sequence: MVDYYEVLGVQKHASAEDIKKAYRKLALKWHPDKNPENKEEAEQQFKQVAEAYEVLSDAKKRDIYDRFGKEGLINGGGGGSHHDNPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFEDFFGGRRGPRGSRSRAGGSFLSAFGGFPAFGNAFPSFDTGFTSFGSLGHGGLTSFSSTSFGGSGMGNFKSVSTSTKIVNGRKITTKRIVENGQERVEVEEDGQLRSLTINGEANEEAFAEECRRRGQHALPFQPTNTRLLKPHKPASSPRYAYHYNSDEVEEQEKSRVASSLETPFYLSGYKEGSKRRKQKQREEQKKKKSTKGSY
What is the function of this protein?
Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70.  Plays an indispensable role in the organization of KRT8/KRT18 filaments.  Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin.  Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins.  Also reduces cellular toxicity and caspase-3 activity.
What are the official names of this protein?
DnaJ homolog subfamily B member 6.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Nucleus. Cytoplasm, myofibril, sarcomere, Z line.
Protein: BAMC_OCESG
Sequence: MISLLAVAVLAGCSNPETRSQANRGFDYEQETLRTAPLLIPEGLQAPRFNTEYVIPKGTAQGVTGKVLDIRPPTQVLPLVRGSEAMTEGSGLWFYQQRLDQPLERELNQALTVFFEQTDTDYDAVANGFESSGDAIGAPSQQFRWQLMPDAVRRAVAVQVQSTEGGGVLAQDRLRAEASMLNAFSLSYQRELSRQQELLDQGPIALTLDAGQGLLLAEQDYDRTWKRLITLLPRLGFDISNRQQALGYVDVEFDGLSKGDWQDLRLPALDIPEQEYRIQLGDLGSRTSLSLSNKDREPVAADVLSKLVNTLAPAFERTDLVR
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamC.
What is the protein family that this protein belongs to?
Belongs to the BamC family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: KARG_PENJP
Sequence: VDAAVLEKLQAGFKKLEAATDCKSLLKKYLSKDIFDKLKGQKTSLGATLLDVIQSGVENLDSGVGIYAPDAEAYTLFAPLFDPIIEDYHVGFKQTDKHPNKDFGDVSSFVNVDPEGQYVISTRVRCGRSMEGYPFNPCLTEAQYKEMQQKVSSTLSSLEGELKGTYFPLTGMSKEVQQKLIDDHFLFKEGDRFLQAANACRYWPAGRGIYHNDNKTFLVWVNEEDHLRIISMQMGGDLGQVFRRLTSAVNEIEKRIPFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANRDKLEEVAGKYNLQVRGTRGEHTEAEGGIYDISNKRRMGLTEFQAVKEMQDGILQLIKMEKEM
What are the official names of this protein?
Arginine kinase, AK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: NAGD_STAES
Sequence: MKHYQAYLIDLDGTMYKGTDEIDGAAQFIDYLNNNHIPHLYVTNNSTKTPVQVTEKLREMHIDAKPDEVVTSALATADYISEQHPNATVYMIGGHGLKTALTDAGLSIKNDEHVDYVVIGLDEKVTYEKLSIATLAVRNGAKFISTNPDVSIPKERGFLPGNGAITSVVSVSTGIQPEFIGKPEPIIMSKSLDILGLEKSEVAMVGDLYDTDIMSGINVGIDTIHVQTGVSTYEDIQSKEIPPTYSFKDLNVAIAELEK
What is the function of this protein?
Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
What are the official names of this protein?
Acid sugar phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. NagD family.
Protein: PURA_BARQU
Sequence: MANVVVVGTQWGDEGKGKIVDWLSERADIVVRYQGGHNAGHTLVVNGVNYKLSLLPSGLVRGKLSIIGNGVVVDPHHFVAELKKLRDQGVKITPEILRIAENAPLILSLHRDLDATRESGLSGLKIGTTKRGIGPAYEDKVGRRAIRVMDLAETNTLMAKIERLLAHHNALRRGMGVAEINSQALYDELMQVADEILPFMDCTWRLLDESYQVGKHVLFEGAQGALLDNDFGTYPYVTSSNTVAGQACTGSGIGPGVIHYVLGIAKAYTTRVGEGPFPTEQINDIGEFLGMRGKEFGVVTGRKRRCGWFDAVLVRQMVTICGVQGIALTKLDVLDGLDEIKICIGYELDGKRINYLPSSMGAQARVMPVYETLEGWKEATAHALSWEDLPPQAVKYIRYIEKLINARVALLSTSPEREDTILVTDPFAD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOBN_BACSU
Sequence: MNSLMNDDMVKIIRNGLSASQHPKHILVIGAGLSGLVSASLLKNAGHRVTILEASGRAGGRVCTLRSPFSDDLYFNAGPMRIPNNHSLTLEYIKKFKLPTNVFINRTPMDIIYANGIKTRLQVFERAPGILRYPVAPNEQGKTSEELMLSLLQPILNFINQNPARNWRIVEEQYKNHSLSSFLNTYFSYGAIDMIGVLLDMEAYMGMSLVEVLRESIFFSSPAHFYEITGGMDLLPHAFLPQLKTNILYHQKMMKMSQGENRVTIHCQHQQTAEFTSFTADLAIVTIPFSTLRFVKVEPYHSFSYYKRRAIRELNYISATKIGIEFKSRFWEKAGQHGGKSITDLPIRFSYYPSRNIGANGHAVILASYTWADEALIWDSLSEGERIQYTLLNLSEIYGDIVWSEFVSGTSFSWSQYPYSAGGFTAFEPGQELELYPYIPVPEGRVHFAGEHASLTHAWMQGAIESGIRVAYEVNRLP
What are the official names of this protein?
Putative L-amino-acid oxidase YobN.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
Protein: PYRDB_BACVZ
Sequence: MLEVNLPGLQLKNPIIPASGCFGFGKEYAGFYDLSCLGGIMIKATTNEARFGNPTPRVAETSAGMLNAIGLQNPGLEHVLNHELPWLEQFDTPIIANVAGSQVDDYKEVAEHISQAPNVHALELNISCPNVKTGGIAFGTDPVMAAELTKAVKEVSAVPVYVKLSPNVANITEIAKAIEAAGADGLTMINTLIGMRLDLKTGRPILANKTGGLSGPAIKPVAIRMVYEVSQAVHIPIIGMGGVQTAEDALEFLLAGASAVAVGTANFVNPFVCPEIIEQLPRVLRQYGFQSVSECIGRSWKHEKQPAHHRA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RO32_XENLA
Sequence: MPRGGMDDHWPSSDDQGHEPKEPEQLRKLFIGGLSFETTDDSLREHFEQWGKLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDASMSARPHKVDGRVVEPKRAVSREDSARPGAHLTVKKIFVGGIKEDTEEYHLRDYFEGYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINLHNCEVKKALSKQEMQTASAQRGRGGGGSNFMGRGGNYGGGDGGGGGNFGRGGGFGNRGGYGGGGGRGGGYGGGGDGYNGFGGDGGNYGGGPGYGGRGYGGSPGYGNQGGGYGGGGGGGGAGGGGYDGYNEGGNFGGGNYNDFGSYGGQQQSNYGPMKAGNFSGRSTGGSGGSSSGPYGGGYGSGGGGGGGGGGSYGGRRF
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein A3 homolog 2, hnRNP A3(B).
What are the subcellular locations of this protein?
Nucleus. Note=Component of ribonucleosomes.
Protein: TPIS_BAUCH
Sequence: MRHPLVIGNWKLNGSKHMVSNFIISLRNQLSNMINCCNVAIAPPMIYLDRAKSYLTGSHIALGAQNVDLHVSGAFTGEISAKMLKDIGAKYIIIGHIERRLYHKESNEDIANKFACLKNEGLIPVLCIGETKEENEKDQTKAICVRQLDYILNIVGTQAFKNAVIAYEPIWAIATGKSANPLQIQKIHKFIRSYLFNHDQAIAEQVIIQYGGSVNASNAAELFNQPDVDGALVGGASLKADIFATIIKAAARAKKN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_NITEU
Sequence: MGQKINPTGFRLSVLKNWSSRWYTNTKKFSDFLNEDISVRQYLQKKLAHASVGSIIIERPSKNAKITIHTSRPGVVIGKKGEDIEILRRNVEKLMNVPVHINIEEIRKPEIDAQLIAASITQQLEKRIMFRRAMKRAIQNAMRLGAQGIKIMSSGRLNGIEIARTEWYREGRVPLHTLRAEVDYGTSEARTTYGIIGVKVWVFKGEQLGIKERQN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: AIM32_YEAS6
Sequence: MLRITVKTLQQRASFHHSFKHISVPDLHTRAQNDQTNCYCQEINARLPSKTDPLDPHIKLPHRTPNYNKHVLLLSPGDRFAQPWKVAWNHNLDTNTNRPYNAISKLRSHLGGSPGILINAAHLQNEFIPRPKQHDEWLYFFVIPDMKLYVIKETDIEEFASFLDEGAIQAPKLSFQDYLSGKAKASQQVHEVHHRKLTRFQGETFLRDWNLVCGHYKRDAKCGEMGPDIIAAFQDEKLFPENNLALISHIGGHIFAGNVIFYKLFGREKMQNKLDSLWFGKVYPHNLKLLCENLENGKIIDEMYRGGISMN
What are the official names of this protein?
Altered inheritance of mitochondria protein 32.
What is the protein family that this protein belongs to?
Belongs to the AIM32 family.
Protein: NS3B_CVPPU
Sequence: MIGGLFLSTLSFVIVSNHSIVNNTANVHHIQQERVIVQQHQVVSARTQNYYPEFSIAVLFVSFLALYRSTNFKTCVGILMFKILSMTLLGPMLIAYGYYIDGIVTTTVLSLRFVYLAYFWYVNSRFEFILYNTTTLMFVHGRAAPFMRSSHSSIYVTLYGGINYMFVNDLTLHFVDPMLVSIAIRGLAHADLTVVRAVELLNGDFIYVFSQEPVVGVYNAAFSQAVLNEIDLKEEEEDHTYDVS
What are the official names of this protein?
Putative non-structural protein 3b, ns3b, Accessory protein 3b, Non-structural protein 3-1, X2b protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses NS3b protein family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: DAPF_CHESB
Sequence: MAELAQFAKMNGLGNAIIVADMRGRADRVRPEAAQRLASDPATHFDQIMAIHDPRLEGTENYIEIINSDGSVAQACGNGMRCVVQRLAAETGRPSFTFETIAGVLSAEEHANGLISVDMGKPRFGWQDIPLAEEFHDTRKIELQVGPIDKPVLHSPSVASMGNPHAIFWVEDDPYSYDLERFGPMLENHPIFPERANITIARVDSPEELTMRTWERGAGLTLACGSAACAAAVSAARTGRTGRGVKVNLPGGSLEILWRDDDHVIMTGPAEWEFSGRFDPATGAWERETEGAA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_HAEDU
Sequence: MKSYQDNIKKLVPEMRRVKQIHFVGIGGAGMSGIAEVLLNEGYQISGSDIVESIVTKHLADAGAKIFIGHQAENIAGASVVVVSSAIEENNPEITAAKSARIPVIQRAQMLAEIMRFRHSIAVAGTHGKTTTTAMLSMIYTEAGLDPTFVNGGLVKSAGKNAHLGASRYLIAEADESDASFLHLQPMLSVVTNIEPDHMDTYGGDFEQMKTIYVKFLRNLPFYGLAVMCADDDVVMEIAPQVGRQVISYGFNANADYRIENYQQTGFQGHYTVICPNNERLDVVLNVPGHHNALNATAALAVAKEEGIANDAILAALADFQGAGRRFDPLGTFKRPNGTVMLIDDYGHHPTEIAVTIKAARQGWQHKRIVMIFQPHRYSRTRDLFDDFVNVLSKVDVLIMLDVYAAGENAIVKADSKALCRSIRNLGKVDPILVSDTSQLGEVLDQIIQDNDLILAQGAGNISKLTRKLAEDWQA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAEC_NEOFI
Sequence: MVPTMIYSAILALSAFTPSVLAQTRSSGCGKQPSLTNGVHNINGREYILKVPDNYDKNKAHHLVFGLHWRGGNMWNIVDGQSVQPWYGLETRAQGSTIFVAPNGKNAGWANNGGEDIAFIDAIIKQVEGDLCVDQSSRFATGFSWGGGMSYSLACSRAKQFRAVSVLSGGVISGCDGGNDPIAYLGIHGINDGVLPFQGGVNLAQKFVKNNRCQQANVGTPQPGSHGSVRTDFKGCSKPVSFIAYDGGHDAAPLGVGSSLAPDATWKFFMAA
What is the function of this protein?
Involved in degradation of plant cell walls.  Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin.  Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan (By similarity).
What are the official names of this protein?
Probable feruloyl esterase C, Ferulic acid esterase C.
What is the protein family that this protein belongs to?
Belongs to the faeC family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPPA_ECO24
Sequence: MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAAGLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQEILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQALQEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIFTELNIQCMTLAGGALREGLVYGMLHLAVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVAANFFDQVEKEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMTLQANHELLTLTLPQGWLTQHPLGKEIIAQESQWQSYVHWPLEVH
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: RL28_METCA
Sequence: MSKVCQVTGKRRIVGHNVSHANNKTKRLFNPNLHERRFWVESENRWVRLKVSNHGLRVIDKCGIDAVLADIRKRGERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RL29_MYXXD
Sequence: MESEMATAKELKELSADDLKQRAAELRETLFQDQLKRRTGSLDNPAERTQHRRDLARVLTVLTQKTKA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PI2R_RAT
Sequence: MVASGGRPDGPPSITPESPLIVGGREWQGMAGSCWNITYVQDSVGPATSTLMFVAGVVGNGLALGILGARRRSHPSAFAVLVTGLAVTDLLGTCFLSPAVFVAYARNSSLLGLAHGGTMLCDTFAFAMTFFGLASTLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCCLFCSLPLLGLGEHQQYCPGSWCFIRMRSPQPGGCAFSLAYASLMALLVTSIFFCNGSVTLSLCHMYRQQRRHHGSFVPTSRAREDEVYHLILLALMTGIMAVCSLPLTIRGFTQAIAPDSREMGDLHAFRFNAFNPILDPWVFILFRKAVFQRLKFWLCCLCARSVHGDLQTPLSRPVSGRRDTLAPDSLQAKEGNWVPLSTWGTGQVAPLTAVPLSGGDGCSVGMPSKTEAVVACSLC
What is the function of this protein?
Receptor for prostacyclin (prostaglandin I2 or PGI2).  The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
What are the official names of this protein?
Prostacyclin receptor, Prostaglandin I2 receptor, PGI receptor, PGI2 receptor, Prostanoid IP receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MCFP_DICDI
Sequence: MATTSVSSPKSKPSWVSFLSGGLAGVTAKSAVAPLERVKILYQIKSELYSLNSVYGSMLKIVENEGIKGLWRGNSATILRVFPYAAVQFLSYETIKNHLVADKSSSFQIFLAGSAAGGIAVCATYPLDLLRARLAIEIHKKPTKPHHLLKSTFTKDGVKGIYRGIQPTLIGILPYGGISFSTFEFLKRIAPLNEIDENGQISGTYKLIAGGIAGGVAQTVAYPFDVVRRRVQTHGFGDAKAVVNLEHGTLRTIAHILKEEGILALYKGLSINYVKVIPTASIAFYTYEYLSNFFNKL
What is the function of this protein?
Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane.  Required for the accumulation of coenzyme A in the mitochondrial matrix (By similarity).
What are the official names of this protein?
Mitochondrial substrate carrier family protein P, Solute carrier family 25 member 16 homolog A.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: REM2_HUMAN
Sequence: MHTDLDTDMDMDTETTALCPSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVGKSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPARRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL
What is the function of this protein?
Binds GTP saturably and exhibits a low intrinsic rate of GTP hydrolysis.
What are the official names of this protein?
GTP-binding protein REM 2, Rad and Gem-like GTP-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. RGK family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RSMH_CUPPJ
Sequence: MSPTGSPATPALRHRTVLLDEAVEALVWRPDGVYVDGTFGRGGHSRAVLARLGPDGALVAFDKDPAAIAEAGTIQDARFSIEHESFAAMGERLAGRGHVAGVLLDLGISSPQIDEAARGFSFRFEGPLDMRMDTTRGITAAEWLAQAEEQDIARVIRDYGEERFAVQIAKAIVARRREPGDGGPLATTADLAALVAKAVKTREKGQDPATRTFQALRIHINQELEDLERGLKAAYDLLQVGGRLVVISFHSLEDRIVKRFMAAHARPQQDADPALRRAPLRAADLPQPTLRLLGRVKPGAQEVADNPRARSAVMRVAEKLAPAASGRGAAPA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.