PharMolix/UniProtQA huggingface dataset:
Protein: CCR4_ENTBH
Sequence: MEEKIKKKDYNKDIDNCDDELEGLDMSFQGIKVIGKEITLLVSLKQLILNNNDIETIPEDISNLIRLEVLDFSYNKIEKIPTELGRLINLKELYLNNNMIVEVPMELGTLYKLENFSILNNPLVHPYGIMSKDKSLLRFCRENNTNYKQPNDRVWIDTVLKIDQSLETYSFGTFNILCSLYASNLTYAPSWVINLECRKDILMQTFIAYNLDILCLQEVDINVFNTFYKEQLAQKLDYDGVILPKKSFDKVTDQPKKFHGIVTFWKKNKFKLIEQVSIDFFQKIINDKRFKYLSDIHTRIFQKTNVGLITIFETCNTNIIIIVANVHLYWNPEFNDIKILQTIIYLEEIEFLKEKYKHAHIVLQGDFNSLQNSHVYQYIINRKLPTNIFDPWDYGSLNNGVTHSLTLRNAYDGHDITFTNFTPSFKAVIDYIFYSKYLNLISIISPIEDEYTKTTIGLPNIHFPSDHILIGAKFQFKSSKK
What is the function of this protein?
Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity).  Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
What are the official names of this protein?
Probable CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4, Carbon catabolite repressor protein 4, Cytoplasmic deadenylase, Glucose-repressible alcohol dehydrogenase transcriptional effector.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PURA_MYCA1
Sequence: MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGENFALHLIPSGVLTPGVTNVIGNGVVVDPGVLLDELKGLEDRGVDTSRLLISADAHLLLPYHVAIDKVTERYMGNKKIGTTGRGIGPCYQDKIARIGIRVADVLDREVLTHKIEAALELKNQILVKIYNRKALDPHQVVECLLEQAEGFRHRIADTRLLLNTALEAGETVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGAAVGSGIGPTRITAVLGILKAYTTRVGSGPFPTELFDENGEYLSKTGGEFGVTTGRRRRCGWFDAVVARYATRVNGITDFFLTKLDVLSSLETVPVCVGYRIDGARINEMPMTQSDLHRAEPIYEELPGWWEDISAAREFDDLPAKARDYVLRLEELAGAHVSCIGVGPGREQTIVRRDILAARP
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_PSEU2
Sequence: MNSQPLRVGIGGPVGSGKTALTLALCLALRDRYNLAVVTNDIYTREDADFLVRNEALAPERIIGVETGGCPHTAIREDASINLEAVDQLNRRFEGLDLIIVESGGDNLSATFSPELSDLTIYVIDVSAGDKLPRKGGPGICKSDLLVINKIDLAPLVGASLEMMDSDTRRMRGEKPFVFSNQKTGQGLEQIIAFIERQGLLTAAA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POLN_HEVCH
Sequence: MEAHQFIKAPGITTAIEQAALAAANSALANAVVVRPFLSHQQIEILINLMQPRQLVFRPEVFWNHPIQRVIHNELELYCRARSGRCLEIGAHPRSINDNPNVVHRCFLRPAGRDVQRWYTAPTRGPAANCRRSALRGLPAADRTYCFDGFSGCNFPAETGVALYSLHDMSPSDVAEAMFRHGMTRLYAALHLPPEVLLPPGTYRTASYLLIHDGRRVVVTYEGDTSAGYNHDVSNLRSWIRTTKVTGDHPLVIERVRAIGCHFVLLLTAAPEPSPTPYVPYPRSTEVYVRSIFGPGGTPSLFPTSCSTKSTFHAVPAHIWDRLMLFGATLDDQAFCCSRLMTYLRGISYKVTVGTLVANEGWNASEVALTAVITAAYLTICHQRYLRTQAISKGMRRLEREHAQKFITRLYSWLFEKSGRDYIPGRQLEFYAQCRRWLSAGFHLDPRVLVFDESAPCHCRTAIRKAVSKFCCFMKWLGQECTCFLQPAEGAVGDQGHDNEAYEGSDVDPAESAISDISGSYVVPGTALQPLYQALDLPAEIVARAGRLTATVKVSQVDGRIDCETLLGNKTFRTSFVDGAVLETNGPERHNLSFDASQSTMAAGPFSLTYAASAAGLEVRYVAAGLDHRAVFAPGVSPRSAPGEVTAFCSALYRFNREAQRLSLTGNFWFHPEGLLGPFAPFSPGHVWESANPFCGESTLYTRTWSEVDAVSSPAQPDLGFISEPSIPSRAATLTPAAPLPPPAPDPSPTPSAPARGEPAPGATARAPAITHQAARHRRLLFTYPDGSKVFAGSLFESTCTWLVNASNVDHRPGGGLCHAFYQRYPASFDAASFVMRDGAAAYTLTPRPIIHAVAPDYRLEHNPKMLEAAYRETCSRLGTAAYPLLGTGIYQVPIGPSFDAWERNHRPGDELYLPELAARWFEANRPTCPTLTITEDVARTANLAIELDSATDVGRACAGCRVTPGVVQYQFTAGVPGSGKSRSITQADVDVVVVPTRELRNAWRRRGFAAFTPHTAARVTQGRRVVIDEAPSLPPHLLLLHMQRAATVHLLGDPNQIPAIDFEHAGLVPAIRPDLAPTSWWHVTHRCPADVCELIRGAYPMIQTTSRVLRSLFWGEPAVGQKLVFTQAAKAANPGSVTVHEAQGATYTETTIIATADARGLIQSSRAHAIVALTRHTEKCVIIDAPGLLREVGISDAIVNNFFLAGGEIGHQRPSVIPRGNPDANVDTLAAFPPSCQISAFHQLAEELGHRPAPVAAVLPPCPELEQGLLYLPQELTTCDSVVTFELTDIVHCRMAAPSQRKAVLSTLVGHYGRRTKLYNASHSDVRDSLARFIPAIGHVQVTTCELYELVEAMVEKGQDGSAVLELDLCNRDVSRITFFQKDCNKFTTGETIAHGKVGQGISAWSKTFCALFGPWFRAIEKAILALLPQGVFYGDAFDDTVFSAAVAAARASMVFENDFSEFDSTQNNFSLGLECAIMVECGMPQWLIRLYHLIRSAWILQAPKESLRGFWKKHSGEPGTLLWNTVWNMAVITHCYDFRDLQVAAFKGDDSIVLCSEYRQSPGAAVLIAGCGLKLKVDFRPIGLYAGVVVAPGLGALPDVVRFAGRLTEKNWGPGPERAKQLRLAVSDFLRKLTNVAQMCVDVVSRVYGVSPGLVHNLIGMLQAVADGKAHFTESVKPVLDLTNSILCRVE
What is the function of this protein?
RNA-directed RNA polymerase: Plays an essential role in the virus replication (PubMed:27324050).  Binds to the 3'-end of the genomic RNA to initiate viral replication (By similarity).
What are the official names of this protein?
Non-structural polyprotein pORF1.
What is the protein family that this protein belongs to?
Belongs to the hepevirus non-structural polyprotein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: RS7_LEUCK
Sequence: MPRKGYTKRQEVLPDPIYNSKLVSRLINKLMLDGKRGTASTILYDAFDRIKEATGNEPLEVFEQAMENIMPVLEVKARRVGGSNYQVPIEVRPDRRTTLGLRWLVNYSRLRNEHTMDERLAKEIMDAANDTGASVKKREDTHKMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: KGUA_SALTY
Sequence: MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRAPRPGEVHGEHYFFVNHDEFKTMIGREAFLEHAEVFGNYYGTSRETIEQVLATGVDVFLDIDWQGAQQIREKMPQARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAEYDYLIVNDDFDTALSDLKTIIRAERLRMSRQKQRHNALISKLLAD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCA_EDWI9
Sequence: MSITMSDSAAKRVQTFLTNRGKGLGLRLGVKTSGCSGMAYVLEFVDVLNEDDVVFEDQGVKVIVDGKSLVYLDGTELDFVKEGLNEGFKFNNPNVKNECGCGESFNV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: TSAD_ECO8A
Sequence: MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPGB_XANAC
Sequence: MHWMLLVSLLLLLWLLVASPRLAWLKAGLLSLFLLLLSAWGLVDRLSGDGINAATLYHLRADMDGAGVSDFSGYIAVFVGMLLLSLSPLLLVRIRRFQRPRGGGAVFAGFVGMLLVGIAASPLYRDGKRLYYQLRPVDYATVVPEYQVPQQPLHKRKNIVWIYGESLERTYFDEQVFPGLMPNLRAVATEAVDVRNLASTEGSGWTIAGMVASMCGVPLTTAPGDENSMDRMGMFLPEARCLGDYLKDQGYRNHYVGGADASFAGKGRFLSSHGFDVVHDVHYFQDQGVAPKHFSAWGVHDDVLLDDAWDTFQTLSRAGQPFLLTTLTMDTHHPAGHLPSACKGQQYDSPLGDIGLLHAIKCSDRLIGELVARIRNSRYGKNTIIVIASDHLAMPNDLSDVLAKQKRENLLLFLGEDIAPQQVVTRAGSTLDSGATLLQLLEPGMRTLGFGRSFLASDAPPSASAAASRDSGKDYPRYLAYARTLWTGRSTRMLRINGNGDVVVGVQQVRPPVLLEYDKDTNLKTVYLENTSRQFDRTHSKGTLAYVDRCTAFEDGSADGDWCALVVDRHQSMKLYRDPDLARGIAIDAPLEATQQGPRPRVRQPIMLTQAARKTDAGRYMLELYAKRRPTRAFWVEAVSSERKVVLAQQWVVPDAAGRIRMPVGLEHAVEDLEIRAWLDYTEDVSVDDLALVKDIPVADRS
What is the function of this protein?
Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones.
What are the official names of this protein?
Phosphoglycerol transferase I, Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the OpgB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: C_PI3B
Sequence: MLKTIKSWILGKRDQETSHLTSHRPSTSLNSYSAPTPKRTRQTAMKSTQGTRDSARQSTNLNPKQQKQAKKIVDQLTKIDSLGHHTNVPQRQRIEMLIRRLYREEIGEEAAQIVELRLWSLEESPEAAQILTMEPKSRKVLITMKLERWIRTLLRGKCDNLKMFQSRYQEVMPFLQQNKMETVMMEEAWNLSVHLIQDIPA
What are the official names of this protein?
Protein C.
What is the protein family that this protein belongs to?
Belongs to the respirovirus protein C family.
Protein: PAX_I83A8
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIVVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFVSPKEAKKQLKKNLKSQELCAGLPTKVSRRTSPALRILEPMWMDSNRTAALRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: GRPE_METTH
Sequence: MCEDKKTDSRSQQECQKELEELRERLKDLENEIKKKEEEVREYTSHLQRLQADFDNYKKQMEKQELEIIKNANERLILKLLDVYEDLERAIENQDSSMDGLEVIYRKFRDTLTKEGLSEIPAEGEKFDPFLHEAVMVEDHDGYEDGIIIEELSRGYRLNDRIIKHSIVKVCKKS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_METPP
Sequence: MLDREGFRPNVGIVLLNQRNQVFWGKRIRTHSWQFPQGGIKYGETPEQAMYRELHEEVGLQPEHVRILARTRDWLRYEVPDHYIRREARGHYRGQKQIWFLLQLTGRDNDMNLRACDHPEFDAWRWNEYWVPLEVVIDFKRDVYQMALTELARFLPRANHHNRYLRSGMRAHRREDEERSNGEAPMEAADGETTPEGPR
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: EXP10_ARATH
Sequence: MGHLGFLVMIMVGVMASSVSGYGGGWINAHATFYGGGDASGTMGGACGYGNLYSQGYGTSTAALSTALFNNGLSCGSCFEIRCENDGKWCLPGSIVVTATNFCPPNNALANNNGGWCNPPLEHFDLAQPVFQRIAQYRAGIVPVSYRRVPCRRRGGIRFTINGHSYFNLVLITNVGGAGDVHSAAIKGSRTVWQAMSRNWGQNWQSNSYLNGQALSFKVTTSDGRTVVSFNAAPAGWSYGQTFAGGQFR
What is the function of this protein?
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found.  Plays a major role in control of leaf growth and influences the mechanical breakage behavior of the pedicel.
What are the official names of this protein?
Expansin-A10, AtEXPA10, Alpha-expansin-10, At-EXP10, AtEx10, Ath-ExpAlpha-1.1.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: GATB_EMENI
Sequence: MFRSCLRHCRRATVRSRTCPRCSHHEIPQLQVVQRQISLSSSFPHIRRLQTSSTDTQERIPIRKQLKQEAKAIKSRKRERREQEEASRHKWELTVGVEIHAQLNTETKLFSRAPTSPSELPNTNVALFDLAFPGSQPEFQVATLLPALRAAIALNCDIQPVSRFDRKHYFYQDQPSGYQITQYYEPFARNGYLDLFRHDGIAPEDGDRVRIGIKQIQLEQDTAKSQEYPPSMQLLDFNRVSHPLIEIITMPEIHTPATAAAFVRKVQAILQSCSAVTTGMEAGGLRADINVSVRLRGDGSGTHQYSGIGGLGQRTEIKNLSSFKAVEDAIIAEKNRQIAVLESGGVVEGETRGWTIGSTETRKLRGKEGEVDYRYMPDPDIPPLLIGKDIISALSNTLPAGPDALIDMLVGQYGLAIEDAKPLVELEDGARLEYYQDVVDILRNLQQDLDSKTQAGLGRVAGNWVLHELGGLLSKAGLAWDAERVTAESLAALIDQLQRKRITGATAKKVLAMLFDGDRRPVAQLLEEENLILRPLSREEYIALASAAIELNPQMVEQIRSKNQLGKLGWFVGQMMRMGEKGRVEAQKADAILRELILGLSQ
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B, Protein NEMPA.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TRUB_PSEAE
Sequence: MAQVKRIRRSISGILVLDKPRGMSSNQALQKVRWLLNAEKAGHTGSLDPLATGVLPLCFGEATKFSQYLLDADKGYETVMRMGITTTTGDAEGELLAERDVTVGRDDLEQALPRFRGDIEQVPPMYSALKKDGQPLYKLARAGEVVEREARSVTITRLDLLSFEPPCATLAVSCSKGTYVRTLVEDLGQVLGCGAHVAALRRTQAGPFALAQAITLETLERVHAEGGPEALDQFLMPEDSGLLHWPVLQLSEHSAYYWLHGQPVRAPEAPKFGWLRVQDHTGRFIGIGEVTDDGRIAPRRLIRS
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs (By similarity).  Osmoprotectant regulator of PLC.
What are the official names of this protein?
tRNA pseudouridine synthase B, Osmoprotectant regulator of PLC, ORP protein, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: SWF1_CANAL
Sequence: MLFTLIVCLTIISSLATFLLLFGDSPSFRNTPIQKLRNSLLSISRDIFQFYHWLDEKLNGQLLKILNWLVPVGYVMVVTVCFQQFLTHTLPMLSSPGLFRLFTIYFSMVLIYASTILAAFSDPGRITTINLKSYPYTPNQLIFFDGKTCSTCHIAKPARSKHCSVCNQCFLLYDHHCVWINNCVGYYNYKWFMLFLISNINMLGYGGWLCYWALTPVSWRKITSTNNANKVTGIFLILCSIFIVITTLFTFLHLRYIYLGVTTNELDKWSEIDHLVGLGVLYQIEPSIANENYVERAILDGNAVYISLKDERILIYNSNVKNFKLQLIQSVEDDLVNIYDHGFWNNLIERLKW
What is the function of this protein?
Palmitoyltransferase that targets several endosomal SNAREs.  Palmitoylates the SNAREs at cysteine residues close to the cytoplasmic end of their transmembrane domain.  May have a role in the cellular quality control of transmembrane domain-containing proteins (By similarity).
What are the official names of this protein?
Palmitoyltransferase SWF1.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. SWF1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GLYA_WOLPM
Sequence: MMSVLKKICGSKNSLKSFDNEVYQSIEKELQRQKSQLQLIASENFASKAVMEAQGSFLTNKYAEGYPGKRYYCGCEHVDKIESLAIERLCKLFGVKFANVQPHSGSQANQAVFASLLTPGDTILGLSLSCGGHLTHGAAPSLSGKWFKSIQYTVNKDTYLLNMDEIEKLALEHKPKLIIAGASAYPRKMDFKRFREIADKVGAYLLADIAHYAGLIAAGEYPSPAEYAHVMTSTTHKTLRGPRGGIVMTNDEALHKKIQSAVFPGLQGGPLMHVIAAKAVAFKEALAPEFKTYSKKVVENAKVLAQELQKHGLDIITGGTDSHIVLVDLRSQKLTGKDVVDSLERAGITCNKNSVPFDTAKPTITSGLRFGTAAETTRGLEAENFKEIAGLINEVIQGLISGNSSSVEKAVKAKVERICSNFPIY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOMA_BUBBU
Sequence: MMAAGPRTSLLLAFALLCLPWTQVVGAFPAMSLSSLFANAVLWAQHLHQLAADTFKEFERTYIPEGQRYSIQNTQVAFCFSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDGTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFRKDLHKTETYLRVMKCRRFGEASCAF
What is the function of this protein?
Plays an important role in growth control.  Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1.  It stimulates both the differentiation and proliferation of myoblasts.  It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: IHFA_STRM5
Sequence: MALTKAEMAEKLFDEVGLNKREAKEFVDAFFDVLREALEQGRQVKLSGFGNFDLRRKNQRPGRNPKTGEEIPISARTVVTFRPGQKLKERVEAYAGSGQ
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: YCF2A_ATRBE
Sequence: MRGHQFKSWILELREILREIKNSHHFLDSWTQFTSVGSFIHIFFHQERFLKLFDPRIWSILLSRNSQGSTSNRYFTIKGVILFVVAVLIYRINNRNMVERKNLYLIGLLPIPMNSIGPRNDTLEESVGSSNINRLIVSLLYLPKGKKISESCFLNPKESTWVLPITKKCSMPESNWGSRWWRNWIGKKRDSSCKISNETVAGIEILFKEKDLKYLEFLFVYYMDDPIRKDHDWELFDRLSLRKSRNRINLNSGPLFEILVKHWISYLMSAFREKIPIEVEGFFKQQGAGSTIQSNDIEHVSHLFSRNKWAISLQNCAQFHMWQFRQDLFVSWGKNPPESDFLRNVSRENWIWLDNVWLVNKDRFFSKVQNVSSNIQYDSTRSSFVQVTDSSQLKGSSDQSRDHLDSISNEDSEYHTLINQREIQQRKERSILWDPSFLQMERKEIESGRFPKCLSGYSSMSRLFTEREKQMINHLFPEEIEEFLGNPTRSVRSFFSDRWSELHLGSNPTERSTRDQKLLKKQQDLSFVPSRRSENKEMVNIFKIITYLQNTVSIHPISSDPGCDMVPKDEPDMDSSNKISFLNKNPFFDLFHLFHDRNRGGYTLHYDFESEERFQEMADLFTLSITEPDLVYHKGFAFSIDSCGLDQKQFLNEARDESKKKSLLVLPPIFYEENESFSRRIRKKWVRISCGNDLEDPKPKIVVFASNNIMEAVTQYRLIRNLIQIQYSTYGYIRNVLNRFFLMNRSDRNFEYGIQRDQIGKDTLNHRTIMKYTINQYLSNLKKSQKKWFEPLILISRTERSMNRDPDAYRYKWSNGSKNFQEHLEQSVSEQKSRFQVVFDRLRINQYSIDWSEVIDKKDLSKPLRFFLSKPLRFFLSKSLLFLSKLLFFLSNSLPFFCVSFGNIPIHRSEIYIYELKGPNDQLCNQLLESIGLQIVHLKKLKPFLLDDHDTSQKSKFLINGGTISPFLFNKIPKWMIDSFHTRNNRRKSFDNPDSNFSMIFHDQDNWLNPVKPFHRSSLISSFYKANRLRFLNNPHHFCFYWNTRFPFSVEKARINNSYFTYGQFLNILFIRNKIFSLCVGKKKHAFWGRDTISPIESQVSNIFIPNDFPQSGDETYNLYKSFHFPSRSDPFVRRAIYSIADISGTPLTEGQIVNFERTYCQPLSDMNLSDSEGKNLHQYLNFNSNMGLIHTPCSEKDLSSEKRKKRSLCLKKCVEKGQMYRTFQRDSAFSTLSKWNLFQTYMPWFLTSTGYKYLNLIFLDTFSDLLPILSSSQKFVSIFPDIMHGSGISWRILQKKLCLPQWNLISEISEISSKCLHNLLLSEEMIHRNNESPLISTHLRSPNAREFLYSILFLLLVAGYLVRTHLLFVSRASSELQTEFEKVKSLMIPSSMIELRKLLDRYPTSEPNSFWLKNLFLVALEQLGDSLEEIRGSASGGNMLGPAYGVKSIRSKKKDWNINLIEIIDLIPNPINRITFSRNTRHLSHTSKEIYSLIRKRKNVNGDWIDDKIESWVANSDSIADEEREFLVQFSTLTTENRIDQILLSLTHSDHLSKNDSGYQMIEQPGAIYLRYLVDIHKKHLMNYEFNPSCLAERRIFLAHYQTITYSQTSCGENSFHFPSHGKPFSLRLALSPSRGILVIGSIGTGRSYLVKYLATNSYVPFITVFLNKFLDNKPKGFLLDEIDIDDSDDIDDSDNLDASDDIGRDLDTELELLTRMNGLTMDMMPEIDRFYITLQFELAKAMSPCIIWIPNIHDLDVNESNDLSLGLLVNHLSRDCERCSTRNILVIASTHIPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHFFTLSYTRGFHLEKKMFHTNGFGSITMGSNARDLVALTNEVLSISITQKKSIIDTNTIRSALHRQTWDLRSQVRSVQDHGILFYQIGRAVAQNVLLSNCPIDPISIYMKKKSCNEGDSYLYKWYFELGTSMKRLTILLYLLSCSAGSVAQDLWSLSGPDEKNGITSYGLVENDSDLVHGLLEVEGALVGSSRTEKDCSQFDNDRVTLLLRPEPRNPLDMMQKGSCSILDQRFLYEKYESEFEEGEGEGALDPQEDLFNHIVWAPRIWRPWGFLFDCIERPNELGFPYWSRSFRGKRIIYDEEDELQENDSGFLQSGTMQYQTRDRSSKEQGLFRISQFIWDPADPLFFLFKDQPPGSVFSHRELFADEEMSKGLLTSQTDPPTSIYKRWFIKNTQEKHFELLINRQRWLRTNSSLSNGSFRSNTLSESYQYLSNLFLSNGTLLDQMTKTLLRKRWLFPDEMKIGFM
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2 A.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: SKEL2_DROME
Sequence: MLAMKDKPWLLLFGLLAALSCLASFGDAAYPYYGTKIGALTRLHHGVSGDVYAVDSRTIFIKKFNYDGEAPAAYFYVGNTARPSNEGAARLRDERGGTASLTRRYRNKDVTLSLPEGKTLRDIKWFSVWCDEFAVNFGDVSIPPNLDFPRPQKISALRGVHGVSSDNIVIVDAQTLLVPNFSYDGEAPDAKFWVGRGQRPTSDGLRIPDENGKENPLRRYERKTIVLTLPEDLTIFDIGHFGVWCEAFTVDFGHVRLPEGLNVPPSLKMLGISPQSKLNCEVLYDDLAFEVRWAVAGESIVVQLVAKLEPNHYMSFGISPNKNISQMIGADAVVAWVDPQTGNGFATDYFLEGKAQCSGGRGACPDTKISEKTNSIRLLNAAMVNGYSIVTYQRSLAATDRLDLPISITGAESVVWAIGPLNDYQEVSFHTFYNKHLHQIEFGRQPKWNCPLPEGARGNSNSSEQEDSAPAAQSSTGGAGYPPAGRPNVEPDEEFYENRAEALHRQPPQRRQETAIITQRRPVPTPKPVNSNGAWDIPAIQCHEPEDGVFYAQMGPTGGKHGYPAITGHVGWGISWYINGLLIPEIHVVRGKTYTFVVEGGNNPDIPAKYHPFYISDDPVGGYEHKREEEKKAVRIYAGVHRSRSGQVTPTGVGRLCNWTPDVEGPPADDYQSFGAYQRTLTLKCDAGEPGVITWKPDRNTPDTVYYHCFTHRYLGWKIHVHDSCDSEAGGLKGAASERHEIRLPAKATVAEPAPVHEDYAGEASVRHETKVSANDNFLLKHQTDLIKNHNMNGTPPKLSFEITKSSEITKLISDGIRAAEALEESLLRNPNLNPNHPNQNPIPNPHQKPNVTPTEISSRPEILLGETHAHTLNASPSASAYPSPSATLPSANLKLPILAAGPHLIHHPPHLHRLHHQPQHAPHPHVHLHHHNLTANLPALAQKTIGLSEFLRPPQNAPLFHPVKLPGRRPFPAPIKKVPASRPILPQQHPHLHPHPQQHPVLLQQQPSLIVSHYRKPIPGLLKPFVKEKPFPLQPLAASVLLLGQPTELGGLNNKGERLKIKGKPKIPVPYVDLEPQGSLQNTAIFNQPGGKGKGDQKPKASSVSISTTPIPLVKRPTVKEPSQEEIASMRPAVNQGFKPDTVIVESGFKPIVRTDGTGVQLPKEIIDQVAHRREDPGTEIDEVMETDTLFLAAQQGGSETQSFEPMFIPSPLDSTNATKVLRVNVKEVSPTASALRLPSAALEHALPSASELIKPTLDELFAEDLNEEELEMEPMPVADDVESLEETTKKDAVTTTINIPRNTTKKPDPDLLEDLFGPDEEELYADELELDMDDRVAAAAERIDTYYLPPDNRKIPDTRVPSGALYTFDGKSVVDSSLVLPPKLDAPDNANVHQRHAQYGLTPLEQLVRTTPQFGVYRGELPQEFRGTEPQPVSEYSHPAPFSRTTPVFSSSSGSTIYPYSSSTGASTSTVSSSASSPLSSSSLRPISTKLQLLKPEGRRA
What is the function of this protein?
Provides structural support to stabilize and organize the microtubule spindle during mitosis (within embryonic somatic cells) and meiosis (within spermatocytes).  The role in mitosis regulation depends on the Ran pathway.
What are the official names of this protein?
Protein Skeletor, isoforms D/E.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Nucleus, nucleolus. Chromosome. Note=Part of a macromolecular complex forming the spindle matrix. During mitosis, associated with chromatin at interphase, redistributes to the spindle structure at prophase (preceding the formation of the microtubule spindle) through to anaphase. Extends from one end of the spindle to the other during metaphase and anaphase, coaligns with the microtubule spindle.