PharMolix/UniProtQA huggingface dataset:
Protein: TOP1_DICDI
Sequence: MEVKQEILTPMKVEKTNGNVPTPPPTTTTTTVMDDDLFDDEASPPQPNKKLKAENGSIKKLTPTPKPAPVTPKPTAAVNGKKPIPKKKPVDSSSDSDSSDSSSDSDSDSSDSDSDSSSSDSSSSDSDVPKKKPISKIPNKPSGTVSKTSKNSPKTTTTTTTTTTTVKSKPAPKVKPEQSSSDDSSSDSSDDSSDDSSSDSSSEEEKPKKKPSKKPAAVKKEITVKKETTTTTKKTPVKKEVEVKKETKTTTTKKVKKEESDDDGEDEKTTTKKKTTTRKRKLKEEEEGEEEEEEGVNKWWDKEDDEDDGTKWTTLIHNGPVFPPAYVPHGIKFMYDGKVVKLTPKQEEVATFYANYLETDHVKKQAFKDNFFKEFKGLLTSEQKEIVKKMDKCDFSHIHTHLKTKKEQRKARSKEEKDAETAEKKKIQEKHGFATIDGFKEKVGNYMIEPPGLFLGRGQHPKTGMLKQRIMPSDVTLNIGEGEVIPPSPIPGEKWKEIVHNNTVTWLAFWRESVNGGFKYVWLAPSSKIKGQADRKKFEVARGLKNCIGDIRKGYQKSFNDESTEKRQLAVALYLIDFLALRVGNEKGEDQADTVGCCSLRVEHIKLESNNTITLDFLGKDSMRYLNTVQIREDAYKVLKTFVKGKKPTDLLFDSLTVTQLNNHLKKQMTGLSAKVFRTYNASITLQKELDKMDTKEFQSIDEKILFYNRCNREVAILCNHQKAPPKNLAETMSKIDEKIQELRDLQDLCRIKIGKTPKSQQEDIESREAERLPKLIQLAITNKKDKDKEKTDKEISFDVKAAFEKSRTLPDAKGKIKEKIAKYEEQIKKQEILKTGKDELKTVALGTSKINYLDPRITVAWCKKNKVPVDKIFTKSLRDKFPWSDVGTDYIF
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand.  TThe free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity).
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I.
What is the protein family that this protein belongs to?
Belongs to the type IB topoisomerase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LACC_STRPD
Sequence: MILTVTLNPAIDVSYPLNELKCDTVNRVVDVTKTPGGKGLNVSRVLNDFGETVKATGCIGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEILEKGPLLSVDEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIKIANLNGKKTVLDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFEALKEVLQDELFEGIEWIIVSLGADGVFAKHKDTFYNVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKANVLGMLNAQEKTTGHVNMANYDKLYQSIKIKEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: S2546_DANRE
Sequence: MTSRRPDSFEGLGYRGREDPAFSGGYSGRSFNNSSSSDLQNWVTTPPDIPGSRNLHFDDRTPQFETAPDEAQSAAPPSEQLNRFAGFGIGLASLFTENVLAHPCIVFRRQCQVNYHARCYHLSPMTAISVMYNVTKTQGPKALWKGMGSTFVVQGVTLGTEGIISECTPLPRELSHKWNPKQVVGHLVLKGLTYVVAMPFYSASLIETVQSEIIRDNPGILDCVKEGLGRVMGMGIPHSKRLLPLWNLVLPTVLHGILHYIISSSIQRLVLYLLRRRNNGSPKHSSPGSGMDTVQSMLDAYFPELMASFAASLCADVLLFPLETVLHRLHIQGTRTIIDNTDLGFEVLPINTQYEGMRDCINAIRREEGTMGFYKGFGSIVVQYSLHATVLQITKMIYSTLLRNA
What is the function of this protein?
Transmembrane protein of the mitochondrial outer membrane that controls mitochondrial organization (By similarity) (PubMed:27543974).  May regulate the biogenesis and dynamics of mitochondrial cristae, the inwards folds of the inner mitochondrial membrane (By similarity).  Could regulate mitochondrial lipid homeostasis and thereby mitochondrial fission (By similarity).
What are the official names of this protein?
Mitochondrial outer membrane protein SLC25A46, Solute carrier family 25 member 46.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: YBHG_SHIFL
Sequence: MMKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTVNLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVKQAQAAYDYEQNFYNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTRAVEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPDKPYHGQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGDEAGHE
What are the official names of this protein?
UPF0194 membrane protein YbhG.
What is the protein family that this protein belongs to?
Belongs to the UPF0194 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: YIDC_PECAS
Sequence: MDSQRNLLLIALLFVTFMLWQAWETDKNPPATTQTIQQATNAVTGDATNQGVPASGQGKLITVKTDVLSLTINTRGGDVEQAHLLAYPDILGSDKPFHLLETTSAFVYQAQSGLTGKNGPDNPANGSRPLFVTTQDSFELADGQSELRIPMTYTAADGVTYTKTFVLKRGDYALNVDYSVNNTSAQPLELTLFGQLKQSIDLPKHRDTGSNNFALHTYRGAAFSSSEDKYKKYSFSDMDEGLNITTNSGWVAMLQQYFATAWIPTTAGANTFYTSKLGNGQAAIGFKAAPVIIAAGSQQNLNATLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKFLHGFIGNWGFSIIAITFIVRGVMYPLTKAQYTSMAKMRLLQPKLQAMRERIGDDKQRMSQEMMALYKSEKVNPLGGCLPLVIQMPIFLALYYMLMGSVELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTYMPVIFTVFFLWFPSGLVMYYIVSNLVTILQQQLIYRGLEKRGLHSREKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HSLV_STAAB
Sequence: MSNTTLHATTIYAVRHNGKAAMAGDGQVTLGQQVIMKQTARKVRRLYEGKVLAGFAGSVADAFTLFEKFETKLQQFSGNLERAAVELAQEWRGDKQLRQLEAMLIVMDKDAILVVSGTGEVIAPDDDLIAIGSGGNYALSAGRALKHHASHLSAEEMAYESLKVAADICVFTNDNIVVETL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALF2_STAEQ
Sequence: MPLVSMKEMLIDAKENGYAVGQYNLNNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTVVKMVEGLMHDLNITIPVAIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVEITSKVVEYAHDRGVSVEAELGTVGGQEDDVVADGVIYADPKECQELVEKTGIDTLAPALGSVHGPYKGEPKLGFKEMEEIGASTGLPLVLHGGTGIPTKDIQKAIPYGTAKINVNTENQIASAKAVREVLNNDKDVYDPRKYLGPAREAIKETVKGKIREFGTSNRAK
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase, FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: ZN724_HUMAN
Sequence: MGPLTFMDVAIEFSVEEWQCLDTAQQNLYRNVMLENYRNLVFLGIAVSKPDLITCLEQGKEPWNMERHEMVAKPPGMCCYFAQDLRPEQSIKASLQRIILRKYEKCGHHNLQLKKGYKSVDEYKVHKGSYNGFNQCLTTTQSKIFQCDKYVKDFHKFSNSNRHKTEKNPFKCKECGKSFCVLSHLTQHKRIHTTVNSYKLEECGKAFNVSSTLSQHKRIHTGQKHYKCEECGIAFNKSSHLNTHKIIHTGEKSYKREECGKAFNISSHLTTHKIIHTGENAYKCKECGKAFNQSSTLTRHKIIHAGEKPYICEHCGRAFNQSSNLTKHKRIHTGDKPYKCEECGKAFNVSSTLTQHKRIHTGEKPYKCEECGKAFNVSSTLTQHKRIHTGEKPYKCEECGKAFNTSSHLTTHKRIHTGEKPYKCEECGKAFNQFSQLTTHKIIHTGEKPYKCKECGKAFKRSSNLTEHRIIHTGEKPYKCEECGKAFNLSSHLTTHKKIHTGEKPYKCKECGKAFNQSSTLARHKIIHAGEKPYKCEECGKAFYQYSNLTQHKIIHTGEKPYKCEECGKAFNWSSTLTKHKVIHTGEKPYKCKECGKAFNQCSNLTTHKKIHAVEKSDK
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 724.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL14_THET8
Sequence: MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL
What is the function of this protein?
Contacts the 16S rRNA of the 30S subunit in two different positions helping to form bridges B5 and B8.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RPOB_STRP6
Sequence: MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSGLKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVRNTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVGRYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKFVYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYFLNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGRVTNEIVWLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQHNGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIADGPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDTKLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDNEVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PSBP_PINPS
Sequence: AYGEAANVFGAPK
What is the function of this protein?
May be involved in the regulation of photosystem II.
What are the official names of this protein?
Oxygen-evolving enhancer protein 2, OEE2, 23 kDa subunit of oxygen evolving system of photosystem II.
What is the protein family that this protein belongs to?
Belongs to the psbP family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: FDHD_ECOSE
Sequence: MKKTQQKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLSN
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREE_BURP6
Sequence: MRTIDKRIAPNVRLAATLVARAPALTLAYDARCKSRLAATLDTGEDVALVLPRGTVLRDGDVLVADDGALVRVAAAHEAVLLVRAPDALTLTRAAYHLGNRHTPVEVGAGCLKLEYDPVLADMLTRLGATVERASAPFQPEAGAYGGGHRHGHDATFAEDYALAQQVFDEHHGHSHSHSHDHDHDHDHDHQHGPCCSHGHHHGHR
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLH22_XENTR
Sequence: MAEDLETMKPSQAPQQPSLPQGSSKTYRSAEHSQALLSGLVALRDSGILFDVVLKVEGKSIEAHRILLAASCDYFRGMFAGGLKEMDQREVQIHGVSYSAMCRIMDFIYTSDLALSVNNVQETLTAACQLQISEVIQFCCDFLVSWVDEENVLELYKLADIFHLNRLTEQLDTFVLKNFITFSQTQMYRQLPLDKVFSLLNSNRLEVASENEVYEGALLYHYTPEQLEKDQVSLLESPKLLEAVRFPLMDLAILQRLHDKLGLCPLKTTVLKALEYHKNESMQPVMQGPNTQLRSEFHCVVGFGGMYSAPYTVLSDQVKYLNPLLGEWRPLTAPHAPRMSNQGIAVLNNFVYLIGGDNNVRGYRAEARCWRYDPRHSRWFQIQSMQQPRADLSVCVLGDFLYAVAGRDYHDELKEVERYDPFTNTWEYVAPLQKQVHAHAAAALDGRMYVACGRRGNTYLKDTFCYDPERDQWASVALSPVRRAWHGMAALQEKIYLIGGSNDDEGFRQDVLEVACYSPKTDQWTLVSPLPAGHGEPGIAVLAKKIFVLGGRSHNQGDRTDYVHVYEAERDYWEDGPRLEDDISGMAACVLTLPRSVLMDTDVWTQEMYMQYMDPVQNLADNASEVMSVSDWEDLDNSGED
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex.  The BCR(KLHL22) ubiquitin ligase complex could mediate the monoubiquitination of PLK1 and regulate its activity in spindle assembly checkpoint (SAC) and chromosome segregation.  The BCR(KLHL22) ubiquitin ligase complex may also be responsible for the ubiquitin-dependent proteasomal degradation of DEPDC5 and the activation of the TORC1 pathway.
What are the official names of this protein?
Kelch-like protein 22.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Nucleus. Lysosome.
Protein: RADIL_HUMAN
Sequence: MFYGTHFIMSPPTKSKLKRQSQLLSSMLSRTLSYKYRDLDSTFSSLGASDDPAELSTQLSAPGVLKVFGDSVCTGTHYKSVLATGTSSARELVKEALERYALDPRQAGQYVLCDVVGQAGDAGQRWQARCFRVFGDSEKPLLIQELWKPREGLSRRFELRKRSDVEELAAKEVDTITAGINAQARRLQRSRAKGTPTPALGDARSSPPPRLRRTVSETSLSPVNALPAAAQGPEEPGPDAMRYSLYQSPHLLLLQGYSQQHDSLVYVLNRDRHTVGQRTPSSKPSISLSAPDILPLHCTIRRQPLPDSGQAAGRLVLEPIPGAHISVNFSEVGHRTVVLHHGDLLSLGLYYLLLFKDPAQAQPLPARALARLRAVPQSCRLCGAALGARGAASPTQAALPRRQQLLLEFEPHLEDTLLQRIMTLIEPGGDDHKLTPAFLLCLCIQHSATHFQPGTFGQLLLKIARLIRETVWEKTKELAEKQAQLQEPISLASCAMADLVPDLQPILFWMSNSIELLYFIQQKCPLYMQSMEEQLDITGSKESLFSCTLTASEEAMAVLEEVVLYAFQQCVYYVSKSLYICLPALLECPPFQTERRESWSSAPELPEELRRVVSVYQAALDLLRQLQVHPEVASQMLAYLFFFSGTLLLNQLLDRGPSLSCFHWPRGVQACARLQQLLEWMRSAGFGAAGEHFFQKLSCTLNLLATPRAQLIQMSWTALRAAFPALSPAQLHRLLTHYQLASAMGPMSTWEPGAQDSPEAFRSEDVLESYENPPPIVLPSDGFQVDLEANCLDDSIYQHLLYVRHFLWGLRSRASPGSPGRPGSGASQPVCPEGMHHVVLDGHLEAPSCPLAPRDPGPAAREVAPERTLPLRGAPWAQAPPGRQPSRGGSQAGPPHTDSSCLLTPPSTPLGPEPGDPDWPESGGPCGKALPERQRNGLSGLRGAAPEGDSAALAEESPPAPSSRSSSTEDFCYVFTVELERGPSGLGMGLIDGMHTHLGAPGLYIQTLLPGSPAAADGRLSLGDRILEVNGSSLLGLGYLRAVDLIRHGGKKMRFLVAKSDVETAKKIHFRTPPL
What is the function of this protein?
Downstream effector of Rap required for cell adhesion and migration of neural crest precursors during development.
What are the official names of this protein?
Ras-associating and dilute domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the RADIL family.
Protein: CER1_MOUSE
Sequence: MHLLLVQLLVLLPLGKADLCVDGCQSQGSLSFPLLERGRRDLHVANHEEAEDKPDLFVAVPHLMGTSLAGEGQRQRGKMLSRLGRFWKKPETEFYPPRDVESDHVSSGMQAVTQPADGRKVERSPLQEEAKRFWHRFMFRKGPAFQGVILPIKSHEVHWETCRTVPFNQTIAHEDCQKVVVQNNLCFGKCSSIRFPGEGADAHSFCSHCSPTKFTTVHLMLNCTSPTPVVKMVMQVEECQCMVKTERGEERLLLAGSQGSFIPGLPASKTNP
What is the function of this protein?
Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part, through a BMP-inhibitory mechanism.  Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak.
What are the official names of this protein?
Cerberus, Cerberus-like protein, Cer-l, Cerberus-related protein.
What is the protein family that this protein belongs to?
Belongs to the DAN family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS13_WOLSU
Sequence: MARIAGVDLPKKKRIEYALTYIYGIGLKTSRDILSAVNISLDKRVQELSEDEVSLISKKIQESYAVEGDLRKKVTMDIKALMDLGSYRGLRHRKGLPVRGQTTKNNARTRKGKRKTVGSASK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: IF2_MYCA1
Sequence: MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRESFGGGKAAEGAAKAPAKAAAKGDAKTAAKGDVKAPDKALDAALDNAIKAGGNGEAAAPPAQPGGTATTPAAQATPEAPARPGPAAARPSAPAPGQPKPPAPGQPPRPGATPGPRPGPAPKPAARTPRVGNNPFSSAQPVDRPIPRPVPRPGAPRPGAPRPGASPGNMPPRPGGVGGPGRPARPGAPRPGGGRPGGPGGRDGGGGNYRGGGVGAPPGGGGGFRGRPGGGGGGRPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFAEKIDANPASLVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLESFDLTYGEDEGTEEDLQTRPPVVTVMGHVDHGKTRLLDTIRKANVREAEQVTVEHDGVERPITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDVEGADPQKIRGQLTEYGLVPEEFGGDTMFVDISAKQGTNIDQLLEAVLLTADAALDLRANPDMEAQGVAIEAHLDRGRGPVATVLIQRGTLRVGDSIVAGDAYGRVRRMVDEHGDDVEEALPSRPVQVIGFTSVPGAGDNLLVVDEDRIARQIADKRSARKRNALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIQIDDEVALRVIDRGVGGITETNVNLASASDAVIIGFNVRAEGKATELANREGVEIRYYSVIYQAIDEIEKALRGMLKPIYEENQLGRAEIRAIFRSSKVGIIAGCMITSGVVRRNAKARLLRDNVVVSENLTINSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVQKERT
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_COLP3
Sequence: MPRRRVVGQRKILPDPKFHNELLAKFINILMVDGKKSTAEKIVYGALDILAQKSEKDQLELFEEALDNIRPSVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWLVEAARKRGEKSMAQRLANEMLDASDSKGSAVKKREDVHRMADANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: DNAK_EXISA
Sequence: MGKIIGIDLGTTNSCVAVMEGGEAVVISNAEGNRTTPSVVAFKGEERQVGEVAKRQAITNPNTIQSIKRHMGTSHTVDVDGKKFTPQEISAIILQKLKKDAEDYLGESVTEAVITVPAYFNDAERQATKDAGKIAGLDVKRIINEPTAAALAYGLDKGEDHTILIYDLGGGTFDVSILELGDGVFEVVATAGDNRLGGDDFDQKVIDYLVAEFKKENGIDLGKDKMALQRLKDAAEKAKKDLSGVTSAHISLPFITAGEAGPLHLEMTLTRAKFEELTADLVERTMEPTRRALKDAGLTPSDLDKIILVGGSTRIPAVQKAIHDFTKKEPFKGVNPDEVVALGAAIQGGVLAGDVKDVVLLDVTPLSLGIETMGGVMTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAPDNKTLGRFQLTDIPPAPRGVPQIEVKFDIDANGIVHVSAKDLGTNKEQSITIQSSSGIDEAEIERMVKEAEANAEADNKRKEEAELRNETDQLVFATDKAIKDLGEQVEEADKEKAEAAKEKAKTALEGSDLEAIRTAKDELSAVVQELTQKVYAKMAEQQGAEGAEPQAEAKQDDNVVDAEFEDLDDRK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RHSB_DICD3
Sequence: MLNDILSRVARVGAMHAGNRPNPPADRPQPCQGKPPTSPGKTIKHKSFLGALAGAVAGALVAAAVAAAAVFLVGVTGGLAVAAVGALAVFAAGDLISAVTNKVSAVVDSASPAFGPVASGSGNVFVEKQPVARATKDTVACTKHNSPQLIAQGSESVFVNDAPAARIDDKTVCGATLKEGASTVFFGSGQGTYLEIADEFSWWEKALLIAVEFLVPPSRGMLKGLGKLFTRNGLKSVLKGAKAGALFITKVPGKMGCAARAFKANKGMARFKEAAKAFKKDPVYLASGEVIESRTDIELGQTLPLVFERTYRSASAHTGLLGRGWHDSWSEVATVTHDGLNTHVVITLAQGYDIDFTFHQDVQAVYCPHYPEFTLHRRGDGFSLWHRDQQTWRDFSVVQGERRLLSAIHDSHDNRIELVRDPKGYLRQLRHSDGVTLLLVWQGEYLHQIQRIDGGQKTLLAEYRQDEQGRLVEANATHAYHLYYEYNTAHRLTRWHDNDQTWARYEYDAQGRCVYTTCADGFLTARFDYLPDRVVMTDGLGQRSEFGFNDLHLMSWEQSPLGHITRYEYDEVGNLLREISPAGRVVEFTYLDDTGRVSTFTDGSGHQWQYDYDDAQRLCGVTDPLGREWGWVYDAEGNPERLTGPDASEVRFTWNRYGLLTQVSDAAGEVQARLQYDHRQRLLSATDAESRTRQLRYDRQDRVVQWQRADGARFRLGYRRASWTLPEQLIRPDDKEEQRQYDRHNNLLSYVDGNGALWRQTFGPFDLLTARTDAEGRTWRYEYDRESQQLIAVTAPDGSRWQWWLDADGRVIRERDMTGTETHYGYDEDGLCIRVRNGEGDTRHFLYDARGLLLRETAPDDTLHYRYDAAGRLTEVSSATAHVQLDYDLRDRVVREWHNGTLLTRQYDDAARTVTRTLTWDGDADDTTGTLAPLTSLFHYTRTGELRQVQLPDGADLTLTHDAAGRESLRTGGSGFVQQREYDVMGWLTREQSGAQHDGRLQPAQTREYRYDGAGNLTGVRHNRDAEGYRLDATGRVQEMLSGGAGKPVDTTARFHYTRTGLPQEAGRLTEWQAGRLVQHDDTHYQYDRAGRLIRKQVVQPGYRPQVWQYRWDSRNQLRVVDTPNGERWLYRYDPFGRRVGKRCDQKAEETRYLWDGDQIAEIRHYRHGQLIQRRHWVYNGWELVVQQRQHTGGDWETDFVTSSQNGTPQALFTPDGTLRWQVPKATLWGQRQTEKSESPDPGLAFAGQLRDSESGLCYNRFRYYDPAGGCYVSPDPIGIAGGESNYGYVQNPNTRVDPLGLAGCAMGEILADADKWSLAKIGDRQKGMIKDKLSTVKERSKALNTKMREHFNANEQKIISEWEKQTGMNWPTLSSGSRATPHHVIPIKNGGSNEWWNIIPVQHPHTGTIHGTGSALRTHLPYQKDGGKLWNLLGY
What is the function of this protein?
Toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system.  This protein may be a nuclease that is specifically inhibited by its cognate immunity protein RhsBI.  Upon expression of the C-terminus (residues 1284-1436) in E. coli growth is inhibited, cells elongate, nucleoids condense and plasmid DNA is degraded; these effects are blocked specifically by cognate immunity protein RshIB.  Cell contact is necessary for growth inhibition.
What are the official names of this protein?
Probable deoxyribonuclease RhsB, DNase RhsB, Toxin RhsB.
What is the protein family that this protein belongs to?
Belongs to the RHS/WapA nuclease family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RT12_ALLCE
Sequence: MPTFNQLIRHGREEKRRTDRTRALDQCPQKQGVCLRVLTITPKKPNSALRKIAKVRLTNRHDIFAYIPGEGHNSQEHSIVLVRGGRVKDLPGVKFHCIRGVKDLLGIPDRRRGRSKYGAEKPKSK
What is the function of this protein?
Protein S12 is involved in the translation initiation step.
What are the official names of this protein?
Ribosomal protein S12, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CH602_ALBFT
Sequence: MNPKQLIFHDDARDKIRRGVDTLAQAVKVTLGPRGRTVILERDFGSPQIVNSGVLVAKSIELEDRFENMGAQLLREVAARTSEMAGDGTTTATVLAHSMILEGLRYLAGGMNPMDLKRGIEIAIDAVVAELKQLSRPCASSQEIAHVAAISANNDRSIGDLLASAIDKVGREGAISIEDGSGLVSVLDVVEGLQFDRGFLSPYFINNAERQSAVLEDVAILLCEGRLSSLKDLLPLLEEIVKEGRPLLVIAEEVDNDSLAALVINTIRGTLKTCAVKAPGFGDRRKAMVQDIAVLTGGSVVSDEVGLTLGKVKLSDLGRATRAEITKETTTLIGGAGQPKAIKERIATIRKERELASSDYDRDKLDERAAKLAGGVALIKVGAATETELKERKIRVEDALHATRAAVEEGIVPGGGVALLRARRALLTLTGSTLDETSGIRLVARSLEEPLRCIVSNAGDEPSVILNRVDESPDPAFGYNAATRTYGDLLQMGVIDPAKVTRLALQNAASIASLILGTACLIATAPKPLPEEGAHGPGGETPMF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.