PharMolix/UniProtQA huggingface dataset:
Protein: VPS10_KLULA
Sequence: MFWWNILIWLGLWNFLPVLAQDFKPKVSFHSDVDTHGRLSILGFDDSRVVLKLLRGVELYRSEDNGVTWDSVGLPLSSDNKPQEWNHLVLDRIYKADVAYLSGENGVLATGDKGKSWKQLTFLDADNHKIDFSDYSNVGDENRKPIINVEIESHPTNKNARIINIYELGKLDGKFTLRQISFYSKDGNNFKLASSGSKSNDDSNPLNMFCSFVQKSSKSKLYKLKDKVICQESTVLSPFGDVSSKLYITDVNFKSLSPFAEQLQDLSPASTFISDNHLFILTLSDRFNENSAANLWRLEDDSTDKFEQISLGTQIRKSLMDVNEIDGRAIITIYHRERNKDGDNNDDEDKSPFEDIFSGSIEALISDSYGKNFRHLSFDEQKASSLTLSTSIFVKKTMFATWTNTMRDFGFFDFRSKVSFDLGNTWSKLKVSDPEGKWNYNCDINSDSNDCGFQMFIVYGGGVEGDSDIFSPGIIAAIGDVYEENPSGDFLKMGTFISRDDGSTWEKVLDFPSRVVMGDYGNIILAVPFDPESDKDPQSEFYFSLDQGKTFQEYQLDKSFYPTELLPSALDGSGNSFMLVGTIMSEDYQNLESVSYVVDFSDAFKGASCKTSDMEDWYYSNGQCVDGTILKFRRRKQDAQCLIKTTYKDLTFEEELCGCSELDYECADDFSIDSAGKCVPDFSKASLMEKCESKKSIQLEPKKISKTTKCKRPQNIIKEEISCAAVPAPSNVKVTENKFSSIFKSYQYFDTFVRESILFRTDKSEAYVSHDGGQNIKQIQTGGEDILEINFNPFFNSSAYLFGKNKNLFATHDYGLSFKVTELPAGRQLGFPLSFHAKDIQTFIYYGGESCESFFDPNCHAVAYITRDGGASFEKLLEGASNCEFLESAVESPRVENGIVCMVKDKSTGARSYVSSTDYFKTQTVLYSDILGFMSTGGYIVVAVSHGERQLRAYLTIDGVEYSEAVLPADLDSYEQKAFTVLGSQEGAIFMHMTTNLDKNEEFGALLKSNTEGTSFVILERAVNRNSFGFVDFEKIQGLEGIILINTVANAKEIVESKDKTSQKKLKTKITFNDGADWTYIKPPSVDSEGKKYNCNPKNLEKCSLNLHGFTERKDVRDTYSSGSAIGYMFALGNVGEYLTPVSEASTFMTNDGGISWSEVKKGSYQWEYGDHGSVLVLVKDNEPTDTVSYSINGGKTWKDYQFASEKINVYDLVTVPRDSAMRFLVIGSSVNVRGEETRTYTLDFVDMFSRQCQYSKDDLKDFEYISLSHPNTKECLFGHKAKYLRKKSDDCYVGMAPLEDKFRIFANCSCTRNDYECDYNFMRVSDGTCKLIDGLKPADPKDICSKDNSLIEYFEPTGYRKIALSTCNGGLMLANSDSPHPCPGKEKEFKEKYKVNHTSFLAIWIFAVLIFTGMLSFIYYRGIKRNGGFARFGEIRLGDDDLIEENNTDRAVNTVLRNGVFLFSNVYTGLQYFGHQVGNFFKRGLSRFGNTTGPSYQSLLHDQFLDDADDLLVGHDEDADDLASFIENEGNFEIGNDEEVDLSSDTPTHAPYSDNPEEANPHEST
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Prevacuolar compartment membrane; Single-pass type I membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: Y3475_YERPE
Sequence: MSDSLWHLYLLRTASGMLYTGITTDVARRLAQHQAGKGAKALRGKGELTLVFHCEAGDRSTALKLEYRVKQLSKQQKEKLVIDQPRLLTTLFLDS
What are the official names of this protein?
UPF0213 protein YPO3475/y0709/YP_0608.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: H6ST1_CHICK
Sequence: MKRAGRTMVERTSKFLLIVAASVCFMLILYQYVGPGLSLGAPSGRPYAEEPDLFPTPDPHYVKKYYFPVRELERELAFDMKGEDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTGWSCGLHADWTELTNCVPGVLGRRESAPNRTPRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPSCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSLVGCYNMSFIPENKRAQILLESAKKNLKDMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQYNSTRAGGVEVDNDTIRRIEELNDLDMQLYDYAKDLFQQRYQYKRQLERMEQRIKNREERLLHRSNEALPKEETEEQGRLPTEDYMSHIIEKW
What is the function of this protein?
6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate (By similarity).  May also play a role in limb development.
What are the official names of this protein?
Heparan-sulfate 6-O-sulfotransferase 1, HS6ST-1, cHS6ST-1.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: SSRB_CANLF
Sequence: MRLLASVLLALFAVSHAEEGARLLASKSLLNRYAVEGRDLTLQYNIYNVGSSAALDVELSDDSFPPEDFGIVSGMLNVKWDRIAPASNVSHTVVLRPLKAGYFNFTSATVTYLAQEDGPVVIGFTSAPGQGGILAQREFDRRFSPHFLDWAAFGVMTLPSIGIPLLLWYSSKRKYDTPKSKKN
What is the function of this protein?
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
What are the official names of this protein?
Translocon-associated protein subunit beta, TRAP-beta, Glycoprotein 25H, gp25H, Signal sequence receptor subunit beta, SSR-beta.
What is the protein family that this protein belongs to?
Belongs to the TRAP-beta family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: PGA10_CANAL
Sequence: MMSFSLLSIVSIALAATVSATSDGTNAYTAYPSVAKTASINGFADKIYDQLPECAKECVKQSTSNTPCPYWDTGCLCVMPQFGGAIGDCVAKNCKGKEVDSVESLATSICSSAGVGEPYWMIPSSVSDALAKAANAASATTSVETATKSAAAELATTSDTTIVASTSHESKVAETSVAQQTASTEKSSAAETSRAKETSKAEESSKAEETSVAQSSSSANVASVSAETANAGNMPVIAIGGVIAAFAALI
What is the function of this protein?
Heme-binding protein involved in heme-iron utilization.  The ability to acquire iron from host tissues is a major virulence factor of pathogenic microorganisms.  Involved in biofilm formation.
What are the official names of this protein?
GPI-anchored hemophore PGA10, GPI-anchored protein 10, Repressed by TUP1 protein 51, Repressed by TUP1 protein 8.
What is the protein family that this protein belongs to?
Belongs to the RBT5 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell membrane; Lipid- anchor, GPI-anchor. Note=Found anchored in the cell membrane as well as a covalently-linked GPI-modified cell wall protein (GPI-CWP).
Protein: SYC_PSEAE
Sequence: MLQIYNTLSKTKEVFTPLVGNQVRMYVCGMTVYDYCHLGHGRSMVAFDVITRWLRHRGYDLTYVRNITDIDDKIINRANENGEPFDVLTERMIAAMHEDEARLNILKPDQEPRATDHIAGMHAMIQTLIDKGYAYAPGNGDVYYRVGKFAGYGKLSRRRVEDLRIGARIEPGEAKEDPLDFVLWKGAKPGEPSWSSPWGEGRPGWHIECSVMSTCCLGDSFDIHGGGNDLEFPHHENEIAQSEAATGKPYAKSWLHCGMITINGEKMSKSLGNFFTIREVLEKYHPEVVRYLLIASHYRSPINYSEENLREAKAALDRFYNALKGLPEAAPAEAAEYVERFAAAMDDDFNTAGACSVLFELAREVNRLRESDLSAAAALAARLKQLAGLLGVLQLEPEAFLQAGAEGKVDAAEVEALIQARLEARAAKNWAESDRIRDQLTAMGVVLEDGKGGTTWRLAD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_PROM3
Sequence: MAFSGHHARKRFAQHWLIDAAVLTQILDAADVQPDDRLLEVGPGRGALTERLLASSASAVHAVELDRDLVSGLRQRFADQARFSLQEGDVLSVPLTLADGRAANKVVANIPYNITGPLLERLLGRLDRPVDHPYQRLVLLLQKEVAQRIRALPGQSCFSALSVRLQLLAHCTTVCPVPPRSFKPPPKVHSEVILIEPLAPEQRLEPLLAKRVESLLRQAFLARRKMLRNTLAKVLPAAELNALADDLGISLQQRPQELSPATWVELARGLNRADLVDPEP
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_STAAN
Sequence: MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLAAHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_RHIME
Sequence: MTDIMTDTQKDTAAGAVPTRSGFVALIGATNAGKSTLVNRLVGAKVSIVSHKVQTTRAIIRGIAIHGSAQIVFMDTPGIFKPRRRLDRAMVTTAWGGAKDADLIMLLIDSERGIKGDAEAILEGLKEVHQPKVLVLNKVDQVRREDLLKLAAAANDVVAFERTFMISALTGSGCEDVMDYLAETLPEGPWYYPEDQISDLPMRQLAAEITREKLFLRLHQELPYASHVETEKWEERKDGSVRIEQVIYVERDSQKKIALGKGGEAIKAISTAARKEISEILEQPVHLFLFVKVRENWGDDPERFREMGLDFPK
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: QOX2_STAHJ
Sequence: MSKFKSLLLMFGTLILLSGCSNVEVFNAKGPVASSQKFLIIYSIIFMLVIVAVVLTMFAIFIFKYSYNKNSETGKMHHNSLIETIWFVVPIIIVIALSIPTVKTLYDYEKPPESKEDPMVVYAVSAGYKWFFAYPEQKVETVNTLTIPKNRPVVFKLQAMDTMTSFWIPQLGGQKYAMTGMTMNWTLQADETGTFRGRNSNFNGEGFSRQTFKVHSVDQSEFDSWVKDAKSKKTLSQDEFDKQLLPSTPNKELTFSGTHMAFVDPAADPEYIFYAYKRYNYVQKDPNFVAEKDLYKDVTDKPQKPARKVQITNANYKRHGMKPMILGNNDPYDNEFKKEEDHNSKEMEKISKSAKDENASKFGSKADNDHGGGH
What is the function of this protein?
Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.  Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I (By similarity).
What are the official names of this protein?
Probable quinol oxidase subunit 2, Quinol oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSAA_PORPU
Sequence: MAISSKEQETKKVKISVDKNPVDTSFEKWAQPGHFSRTLAKGPKTTTWIWNLHADAHDFDSQTSSLEEVSRKIFSAHFGQLAVIFLWLSGMYFHGARFSNYVAWLSNPTGIKPSAQVVWPIVGQEILNGDVGGGFQGVQVTSGWFQLWRASGITTEFQLYCTAIGGLGMAALMLFAGWFHYHKAAPKLEWFQNVESMMNHHLAGLLGLGCLGWAGHQIHLSLPINKLLDSGVSPQEIPLPHEFLINRELMAQLYPSFSKGLVPFFTLNWAEYSDFLTFKGGLNPVTGGLWLSDTAHHHLALAVLFLAAGHMYRTNWGIGHSMKEILEAHKGPFTGNGHEGLYEILTTSWHAQLAINLAMMGSLSIIVAHHMYAMPPYPYIATDYPTQLSLFTHHMWIGGFCVVGAGAHASIFMVRDYNPAENYNNLLDRIIRHRDAIVSHLNWVCIFLGFHSFGLYIHNDTMRALGRSQDMFSDTAIQLQPIFAQWVQSIHTLAPGNTAPNALATASYAFGGEVVSVGNKVAMMPISLGTADFMVHHIHAFTIHVTVLILVKGFLFSRNSRLIPDKANLGFRFPCDGPGRGGTCQVSGWDHVFLGLFWMYNSLSVAIFHFSWKMQSDVWGSVSPSGNVSHITGGNFAQSAITINGWLRDFLWAQASQVIQSYGSALSAYGLIFLAAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKIKVAPAIQPRALSITQGRAVGVAHYLLGGIGTTWAFFLARIISVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PNP_SALG2
Sequence: MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPVRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDTMLGAVVFGHEQQQVVIQAINDLVKEAGKPRWDWQPEAVNDALNARVAALAESRLSDAYRITDKQERYAQVDVIKSETIEQLIAEDETLDANELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDSFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKISTDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKYAIRRIEEITAEIEVGRIYNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRVRLSIKEATEQSQPAAAPEAPASEQAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_METSB
Sequence: MKLPHELGPIHFIGIGGIGMSGIAEVLINLGYSVQGSDAAENANVLRLRRKGAIIHIGHRADNLGDAEVVVVSTAIKRNNPELAYARELRLPVVRRAEMLAELMRLKQCVAIAGTHGKTTTTSLVATLLEAGGFDPTVINGGIINAYGTNSRLGAGDWMVVEADESDGTFLKLPADVAIITNIDPEHLDHFGTFENIRKAFRSFVENIPFYGFAVMCLDHPTVQELVGQIEDRRVITYGENPHADVRLVDIDLAGGMSRFSVVVRDRKSGGETVIEKILMPMPGLHNALNATAAIAVAHQLGMSPDQIRGALAGFGGVKRRFTRTGEWNGAIVFDDYAHHPVEIAAVLKAARASTKGRVIAIVQPHRYTRLHSLFNEFAACFNDADAVIVADVYPAGEAPIEGADRDGLVAAIKARGHRLAMPLARPADLSRLVRQLARPGDYIVLLGAGNITQWAYALPGELAASAA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLIA_BOTJR
Sequence: LANGDEVDPDGHVLNSLIETVMRLQREFANLKYAFLTVHKARSFGSGSERLYVTNKEVKNFEPLGEICSQAGGRIPSPQLENQNKAFASVLERHNKAAYLVVGDSANFTNWAAGEPNEADGTCVKADTHGSWHSASCDENLLVVCEFYFIL
What is the function of this protein?
Inhibits enzymatic, anticoagulant, edema formation, myotoxicity activities induced by snakes phospholipase A2.  Is oligomeric, but it is probable that each of its subunits can bind and inactive a PLA2 molecule.
What are the official names of this protein?
Phospholipase A2 inhibitor BjussuMIP, alpha-PLI.
What is the protein family that this protein belongs to?
Belongs to the alpha-type phospholipase A2 inhibitor family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in plasma.
Protein: GCST_SALPC
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQLDEHHAVRTDAGMFDVSHMTIVDLHGSRTREFLRYLLANDVAKLTKTGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPYAIDITVRDDLSLIAVQGPNAQEKAATLFTDEQRHAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIAMPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYGQEMDEGISPLAANMGWTIAWEPADRDFIGREALEMQREKGHEQLVGLVMTEKGVLRNELPVRFTDAQGNQQEGIITSGTFSPTLGYSIALARVPAGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: SRD2_ARATH
Sequence: MAMKEAFPEDYLSQEELEPSLNVSHHENPLAGRAKRKRTVKNTEVKKRTLKNTEVMKMTEKKTEEAYLVKVEQLAKLKQKQEEDKAAVTLHCFSKTSETGKDVVAPPEGFEQMQSLRFIDNNYTKLKPSDIQGQVDPLFPEVILCVEIYNSRKVKTQEFLVLGRQMLTELKDNIHCATDQVMQKAGKYDPSGYFLIEDVFHNDLRNPSAKDYSYPILDWLWNSKDEALKKWECVLTGELQKKQKLVLGEAKSVDLPRYRTADMQSTHFCDIRFRVGASYVYCHQGDCKHTIVIRDMRMSHPEDVQNRAAYPIMFWPKRRIQKCGVCKIKRASKVAVDDKWASENSSYFCDVCFELLHSEEGPLNCDFPVFDYVHE
What is the function of this protein?
Transcription activator of small-nuclear RNA genes (snRNA), which have essential roles in pre-mRNA splicing and rRNA processing.  Essential protein involved in the establishment of apical meristems and organ primordia, embryogenesis, cell differentiation and cell proliferation, probably by modulating the establishment of auxin gradients.  Participates in the control of competence in cell proliferation; required for the reinitiation of the progression of the cell cycle and subsequent cell proliferation during cell redifferentiation leading to callus formation, especially during the first day of dedifferentiation (e. g.  callus, root and shoot formation from root and hypocotyl explants).
What are the official names of this protein?
snRNA-activating protein complex subunit, SNAPc subunit, Protein SHOOT REDIFFERENTIATION DEFECTIVE 2.
What is the protein family that this protein belongs to?
Belongs to the SNAPC3/SRD2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASCF_ACREG
Sequence: MAFGVEPPEHVTPWFKPVYEATFQFGGVAWTLCYILIAREGMRTKSYGMPLFALANNFAWEMVYALWVVDNAFEKTAMTIWMLIDTPIIYSILKHGVLEWQHAPMVSRNLKSILVGLIALCAAAHWSWQSWWIGNEMGKRDDLEGADLTQMAYWAVSMCQFLVSTMSLAMLCVRGHSGGVSWMIWLSRFLGTLIGLNMNYAWAYYTWPEAHEYFMSAPAVFVWGVTTVCDIIYGFVLYHVKSNERELSDGRKVAAEADDEQVGGWSKMKTGKN
What is the function of this protein?
Terpene cyclase; part of the asc-1 gene cluster that mediates the biosynthesis of both ascochlorin and ascofuranone, a strong inhibitor of cyanide-insensitive alternative oxidases and a promising drug candidate against African trypanosomiasis (PubMed:30952781).  The first step in the pathway is performed by the non-reducing polyketide synthase ascC that produces orsellinic acid by condensing acetyl-CoA with 3 malonyl-CoA units (PubMed:30952781).  Orsellinic acid is then prenylated by the prenyltransferase ascA to yield ilicicolinic acid B (PubMed:30952781).  Ilicicolinic acid B is further reduced to ilicicolin B by the reductase ascB (PubMed:30952781).  The halogenase ascD then chlorinates ilicicolin B to produce ilicicolin A which is converted to ilicicolin A epoxide by the cytochrome P450 monooxygenase ascE that catalyzes stereoselective epoxidation of the terminal double bond of the prenyl group (PubMed:30952781).  Ilicicolin A epoxide is the last common precursor for the biosynthesis of ascofuranone and ascochlorin (PubMed:30952781).  The terpene cyclase ascF produces a monocyclic terpene, and the cyclization reaction is proposed to be initiated by protonation of the terminal epoxide of ilicicolin A epoxide to generate a monocyclic tertiarycation, which is followed by a series of hydride and methyl shifts with abstraction of proton, leading to the formation of the (14S,15R,19R)-trimethylcyclohexanone ring structure of ilicicolin C, which is finally reduced to ascochlorin by the dehydrogenase ascG (PubMed:30952781).  On the other hand, ilicicolin A epoxide is hydroxylated by the cytochrome P450 monooxygenase ascH, and the resultant product is cyclized by the terpene cyclase ascI to ascofuranol via protonation-initiated epoxide ring opening, which facilitates the 6-endo-tet cyclization to form the tetrahy-drofuran ring (PubMed:30952781).  Finally, ascofuranol is oxidized into ascofuranone by ascJ (PubMed:30952781).
What are the official names of this protein?
Terpene cyclase ascF, Ascofuranone/ascochlorin biosynthesis clusters protein F.
What is the protein family that this protein belongs to?
Belongs to the paxB family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SCOC_HUMAN
Sequence: MRRRVFSSQDWRASGWDGMGFFSRRTFCGRSGRSCRGQLVQVSRPEVSAGSLLLPAPQAEDHSSRILYPRPKSLLPKMMNADMDAVDAENQVELEEKTRLINQVLELQHTLEDLSARVDAVKEENLKLKSENQVLGQYIENLMSASSVFQTTDTKSKRK
What is the function of this protein?
Positive regulator of amino acid starvation-induced autophagy.
What are the official names of this protein?
Short coiled-coil protein.
What is the protein family that this protein belongs to?
Belongs to the SCOC family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network. Cytoplasm, cytosol.
Protein: ATG9_COCIM
Sequence: MTSQLITRLLPINSTTSPSIYETIRQYDDDSGHSDTEERAAMAVDEENLDGAYQDYELEGALAQASDTQSTHSSFQSPAAGDSHLPRHPKWTQESVNEAEHDDEVPASLLVEGDGEEDPLPPPPRPPSNRNRILDDAPAAEFCSPRLRGQWEAAEEHQTPHLAPQPSPPLNLHSNRRAGLAFANPKEKAMWRWANVENLDNFLKDVYIYFIGNGIWCIVLSRMLNILTLAFVVGFTTFLTNCVDYRKVPHSKTLNQIIVPKCTNKMSASSTFFLWLFTVFWFGKVFQYIIDFRRLRHMHDFYLYLLDVPDSDIQTISWQEVVGRLMALRDANPATAGTVSTKHRKYIGSQSKQRMDAHDIANRLMRKENYLIALFNKEILDLTLPIPFLRNRQLFSRTLEWNLNLCILDYVFNEQGQLRPLFLKATHRRALSEGLRRRFIFAGVMNIFIAPFIVAYFLMHYFFRYFNEYQKNPSKIGSRQYTPLAEWKFREFNELWHLFERRIHMSYESANMYINQFPKDKTVQLSRFVAFIAGALLSVLALASVIDPELFLGFEITHDRTVLFYIGLFGTVYAVARGVVPDDAQVFDPEHALLDVTAYTHYKPAHWQGKLHSDDVRKEFATLYQLKVVIFLEEILSMIFTPFVLWFSLPKCSDRLIDFFREFTVHVDGLGYVCSFAVFDFKKGTNLMPPEPQHHRPRGLKHGLHDLRGDYFSAKDGKMLASYYGFLDHYAPPARPSGPHASQRQNYPQQPVPGPTHRAQPGANHLHSSRIDRWDNGQHSTMRQSALRTSRFGAITGVGGHASPMASMLLDPHHQPSMSGFRSKAHPTAASRYRPSRQAHPMADTIQDVDEDQLPGINIQPSNVTTTSSGGPATDDSQIEESWRINLAEDANSGEDDEAEDVEKVAGGGGVLGLIHQFQKVTNEGRGAVGM
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y3661_MYCTU
Sequence: MTVSDSPAQRQTPPQTPGGTAPRARTAAFFDLDKTIIAKSSTLAFSKPFFAQGLLNRRAVLKSSYAQFIFLLSGADHDQMDRMRTHLTNMCAGWDVAQVRSIVNETLHDIVTPLVFAEAADLIAAHKLCGRDVVVVSASGEEIVGPIARALGATHAMATRMIVEDGKYTGEVAFYCYGEGKAQAIRELAASEGYPLEHCYAYSDSITDLPMLEAVGHASVVNPDRGLRKEASVRGWPVLSFSRPVSLRDRIPAPSAAAIATTAAVGISALAAGAVTYALLRRFAFQP
What are the official names of this protein?
Probable phosphatase Rv3661.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. SerB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: U78D3_ARATH
Sequence: MAKPSQPTRDSHVAVLVFPFGTHAAPLLAVTCRLATAAPSTVFSFFSTARSNSSLLSSDIPTNIRVHNVDDGVPEGFVLTGNPQHAVELFLEAAPEIFRREIKAAETEVGRKFKCILTDAFLWLAAETAAAEMKASWVAYYGGGATSLTAHLYTDAIRENVGVKEVGERMEETIGFISGMEKIRVKDTQEGVVFGNLDSVFSKTLHQMGLALPRATAVFINSFEELDPTFTNDFRSEFKRYLNIGPLALLSSPSQTSTLVHDPHGCLAWIEKRSTASVAYIAFGRVATPPPVELVAIAQGLESSKVPFVWSLQEMKMTHLPEGFLDRTREQGMVVPWAPQVELLNHEAMGVFVSHGGWNSVLESVSAGVPMICRPIFGDHAINARSVEAVWEIGVTISSGVFTKDGFEESLDRVLVQDDGKKMKVNAKKLEELAQEAVSTKGSSFENFGGLLDEVVNFG
What is the function of this protein?
Possesses low quercetin 3-O-glucosyltransferase activity in vitro.
What are the official names of this protein?
UDP-glycosyltransferase 78D3.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: SYFA_GLUOX
Sequence: MADDLDILRNDTLAALAGAQDRAQWDAIRVGTLGKSGALTGLLKQLGRLEPQERKERGQALNRLRDELTAAIEARGRDIEEEALQARLRSERVDVTMPAPAVVTGTIHPISRTIEEMTAIFGAMGFSVAEGPDIESQWHNFSALNTPEHHPARTEHDTFYLPPKNEDGEPRVLRTQTSGVQIRTMLGSKPPIRIIAPGRTYRADHDATHSPMFHQCEGLVVDRNITLGHLKGCLIEFLRVYFDKPNLPVRFRASYFPFTEPSMEVDIGWSKATGEIGGGSDWLEVLGSGMIHPRVLANCGLDPAEWQGFAFGMGIERLAMLKNGIPDLRSFYESDLRWLRHYGFSAFLPATLTEGV
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.