PharMolix/UniProtQA huggingface dataset:
Protein: MPE1_YEAST
Sequence: MSSTIFYRFKSQRNTSRILFDGTGLTVFDLKREIIQENKLGDGTDFQLKIYNPDTEEEYDDDAFVIPRSTSVIVKRSPAIKSFSVHSRLKGNVGAAALGNATRYVTGRPRVLQKRQHTATTTANVSGTTEEERIASMFATQENQWEQTQEEMSAATPVFFKSQTNKNSAQENEGPPPPGYMCYRCGGRDHWIKNCPTNSDPNFEGKRIRRTTGIPKKFLKSIEIDPETMTPEEMAQRKIMITDEGKFVVQVEDKQSWEDYQRKRENRQIDGDETIWRKGHFKDLPDDLKCPLTGGLLRQPVKTSKCCNIDFSKEALENALVESDFVCPNCETRDILLDSLVPDQDKEKEVETFLKKQEELHGSSKDGNQPETKKMKLMDPTGTAGLNNNTSLPTSVNNGGTPVPPVPLPFGIPPFPMFPMPFMPPTATITNPHQADASPKK
What is the function of this protein?
Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB.
What are the official names of this protein?
Protein MPE1.
What are the subcellular locations of this protein?
Nucleus.
Protein: LFTR_EDWI9
Sequence: MRIMQLDRHSLGFPSPEQALHDPNGLLAIGGDLQPARLLQAYQRGIFPWFSPGELILWWSPDPRAVLVPQALHISHSLRKALRRTTLRITLNQAFAAVIAGCAEQRAEGTWIGPSIQQAYCQLHQLGHAHSVEVWQEERLVGGLYGVAQGSLFCGESMFSRVSNASKMALWSFCSHFQRMGGQLIDCQVLNAHTASLGAHDIPRRRYLQHLLNCRSQTLAPRCWLPQSLTLPLPATATQIGE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHR44_CAEEL
Sequence: MDSISSPSTSSSASSTPKLISEKCLVCFQPSHGNHFGVDSCRACAAFFRRVFVTHKQQFPCREGDNKCTPDEWGRWSCKRCRSDKCFALGMKPDNIQRDRDRFIFSDNFRDDRKRKTSESIVPLSVERFVGKQLVTTYTSTGSGKNIEYITFFDLTPIIKDADYILKRIPKLEKSVKVKSSLEQLAFGLQEVRKEQLFESVPELRKIGKMETWDNWVKGMRRAGEWIMHFEEFRQLEQEEKMVILKCMWHLFIRLERISMTAEMRRMKLCDDKEFIYGTEQRINYDTLEIDRDWFSEATDREVRSFIGPLPRWFCETIIDALMELRPSDVELSFMLCNLCFHLTGQKLGGRIQEITDRLQDVLANDLHKYYLAKDKYSRYSYRLTKLLSLNRQYKNDLEIRRQGIFLANTLNIFRVKLSHPEMFQFSC
What is the function of this protein?
Orphan nuclear receptor.
What are the official names of this protein?
Nuclear hormone receptor family member nhr-44.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PKG2_ADE05
Sequence: MAPKKKLQLPPPPTDEEEYWDSQAEEVLDEEEEDMMEDWESLDEEASEVEEVSDETPSPSVAFPSPAPQKSATGSSMATTSAPQAPPALPVRRPNRRWDTTGTRAGKSKQPPPLAQEQQQRQGYRSWRGHKNAIVACLQDCGGNISFARRFLLYHHGVAFPRNILHYYRHLYSPYCTGGSGSGSNSSGHTEAKATG
What is the function of this protein?
Component of the packaging machinery which encapsidates the viral DNA into preformed capsids and transcriptional activator of the viral major late promoter (MLP).  Binds, along with packaging proteins 1 and 3, to the specific packaging sequence on the left end of viral genomic DNA and plays an active role in packaging of the viral genome into preformed capsids.  Specifically binds to the 5'-TTTG-3' nucleotides of the repeats making up the packaging sequence.  Forms a transcription factor called DEF-A through cooperative binding with packaging protein 1 (Probable).  DEF-A binds to downstream elements of the major late promoter (MLP) and stimulates transcription from the MLP after initiation of viral DNA replication.  Simultaneously suppresses early gene expression and is thus likely to participate in the early-late switch in the expression pattern of the late viral proteins.  May as well enhance transcription from IVa2 and pIX promoters.
What are the official names of this protein?
Packaging protein 2, Packaging protein 22K, L4-22K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae splicing factor family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: MESP1_MOUSE
Sequence: MAQPLCEPRSESWILSPAGRQPPMPSDGNSVCSPAWSSDPWDGAQASSPAPPCARPARRAGTPGRRGTHGSRLGSGQRQSASEREKLRMRTLARALHELRRFLPPSVAPTGQNLTKIETLRLAIRYIGHLSAVLGLSEDNLRRQRHAVSPRGCPLCPDSDLAQSQSLGPRLSPAVCSGVSWGSPPAYPRPRVAAESWDPSFLYAETASQERQEMEPSPSSPLFSSDMLALLETWTPPQEWPPA
What is the function of this protein?
Transcription factor.  Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.  Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.
What are the official names of this protein?
Mesoderm posterior protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: OXYR_BOVIN
Sequence: MEGAFAANWSAEAVNGSAAPPGTEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLSRRTDRLAVLVTWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLATCYGLISFKIWQNLRLKTAAAAAEAAAGAEGEAADWAGRAILARVSNVKLISKAKIRTVKMTFIVVLAFIVCWTPFFFVQMWSVWDADAPKEASPFIIAMLLASLNSCCNPWIYMLFTGHLFQELVQRFLCCSFRRLKGSRPGETSVSKKSNSSTFVLSQYSSSQRRCSQPSTL
What is the function of this protein?
Receptor for oxytocin.  The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Oxytocin receptor, OT-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PROB_STRZT
Sequence: MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKGRVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_CAMJR
Sequence: MYVVFEGIDCVGKSTQISLLKEIYKDAIFTLEPGGTELGKHLREILLNKTHPINKRAELLLFLADRAQHFEEILKTNQNKLIISDRSFISGMAYAKDFENDLLFALNSFALENFFPQKIIFLKGDANLIQERLSQKELDSIEKRGIEYFLSVQDKLEKVLHFLKEKISVEILTLDAKESKEKLHQQIKEFLQ
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: KEFG_ECOK1
Sequence: MMSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSAQELASHARAYGDWLANPLSPGGC
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ODO1_BRUSI
Sequence: MAKQEQAPDRANDVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTRKNWPIAANGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAARDSVRAIMMIRAYRMRGHLHANLDPLGLAEKPNDYNELEPENYGFTPADYNRKIFIDNVLGLEYATVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKLIEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVLSQVMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLEIVNPVVMGKARAKQDLLVGRTRDDMVPLSERPKVLPLLLHGDAAFAGQGVVAECLGLSGLKGHRVAGTLHFIINNQIGFTTNPAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAKVATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEGLVTQDDIDRMKADWRQKLEGEFEAGQSYKPNKADWLDGAWAGLRTADNADEQRRGKTAVPVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGEGIDWATAESLAFGSLAVEGHPIRLSGQDVERGTFSQRHTVLYDQENQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGYEYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGPEHSSARLERYLQLCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRAISTLAELSGESSFHRLLWDDAQYNKDEGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGIDDVYLLRVEQLYPFPAKALINELSRFRHAEMVWCQEEPKNMGAWSFIDPYLEWVLAHIDAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDALG
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: OMPA_SHIBL
Sequence: LTAKLSYPIYDDLDIYTRLGGMVWRADAKNNVGGGDRSNHDTGVSPVFAGGVEYAWTPSIATRLEYQWINNIGDAGTVGTRPDNGMLSVGVSYRFGQDEAAPVVAPAPAPAPQVQTKHFTLKSDVLFNFNKSTLKPEGQQALDQLYTQLSNLDPKDGAVVVLGYTDRIGSDAYNQRLSQQRAQSVVDYLVSKGIPAGKITAQGQGESNPVTGSTCDNVKQRAALIDCLAPDRRVEIEVKGV
What is the function of this protein?
With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm.  Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.
What are the official names of this protein?
Outer membrane protein A, Outer membrane porin A, Outer membrane protein 3A.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: DAPAT_SYNY3
Sequence: MASINDNYLKLKAGYLFPEIARRVNAFTTANPNAQVIKLGIGDVTEPLPLACRQAMAKAIDDMGDRQTFKGYGPEQGYAWLREKIAQHDFQARGCEVNAEEIFISDGSKCDTGNILDIFGKDNTIAVTDPVYPVYVDTNVMAGHTGDANEKGEYGGLVYLPISAENDFVAAIPSKKVDLIYLCFPNNPTGATATKAYLKQWVDYALAHGSIIFFDAAYEAFITDPTLPHSIYEIEGARDCAIEFRSFSKNAGFTGTRCALTVVPKTLTAKAADGSDVELWKLWNRRQSTKFNGVSYIIQRGAEAVYSPEGQAQVQELIAFYLENARIIREKLAAAGLQVYGGINAPYVWVKTPHGLSSWDFFDKLLHTVNVVGTPGSGFGAAGEGYFRISAFNSRANVEEAMERITSTLKLG
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: CLP1_EMENI
Sequence: MSLPGLELTQPSAESQSASAPPTQINLSAGSEWRFEVAFGTTVRVKLLTGTAELFGTELAPSQTYTFSGTKAAIYTWHGCTLEVSAGDAVSGLDGTTSASGRGGLGAGGCQSEYIAEETPMVEYANVHFALEGLRAEAKASGRDGPRVLILGPEDAGKTSLSKILTAYAVKVGREPIVVNLDPTEGMLSVPGTVSATAFRAMLDVEEGWGSSPMSGPSAVPVKLPLVYFYPIVNPLEAEGSVFRPIVSRLALSVMGRMAEDEDAKETGIIVDTPGILSQSRAGALEMINHIVTEFSITTILVIGSERLYSLMMKSYDNKPSSSASSAASDERISVVKLSKSGGCVDRDAAFMKAVRESQIRTYFFGNPVPTTASSALSISSSSTTNVTLSPHAQQLDFDAIALYNYTTSSAEEDQNDEDDYDPAQLTTDSFLPGNNEAESASSLPGLNSAANASAAAAAGALVPLKKVPGPAPSALANTLLAITHASPTSSPSEIRDASTMGFLYVADVDSERGKIRVLAPVGGRVPSRAIIWGKKWPAEVVGLVG
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA cleavage and polyadenylation factor clp1.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS8_SCHPO
Sequence: MFDLNTCLRKNILELQPYRCARDDFSEGVLLDANECAYGSVISVDGVEFNRYPDPRQIEVKQRLCDLRNKELSITKPLTPDNICMGVGSDEIIDSLIRISCIPGKDKILMCPPSYGMYTVSAKINDVEVVKVLLEPDFNLNVDAICETLSKDSAIKVFFACSPGNPTAKALKLEDIKKILEHPTWNGIVVVDEAYIDFSAPDMSALTLVNEYPNLAVCQTLSKSFGLAGIRIGFCLTSKPIATIMNSLKAPYNISEPTSRLALDALSPQSIDKMHTYRDAIIQQRVRLCKELTTIKGMGKIIGGYDANFILIQVLDRPEGGKPSNDAAKYLYLQMATMHKVVVRFRGTEPLCEGALRITVGTEEENTILLKTIKLVLQEYYTKK
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: CPR1_CAEEL
Sequence: MKFLILTALCAVTLAFVPINHQSAVETLTGQALVDYVNSAQSLFKTEHVEITEEEMKFKLMDGKYAAAHSDEIRATEQEVVLASVPATFDSRTQWSECKSIKLIRDQATCGSCWAFGAAEMISDRTCIETKGAQQPIISPDDLLSCCGSSCGNGCEGGYPIQALRWWDSKGVVTGGDYHGAGCKPYPIAPCTSGNCPESKTPSCSMSCQSGYSTAYAKDKHFGVSAYAVPKNAASIQAEIYANGPVEAAFSVYEDFYKYKSGVYKHTAGKYLGGHAIKIIGWGTESGSPYWLVANSWGVNWGESGFFKIYRGDDQCGIESAVVAGKAKV
What is the function of this protein?
Thiol protease.  Has a role as a digestive enzyme.
What are the official names of this protein?
Gut-specific cysteine proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: FX4L4_HUMAN
Sequence: MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEEARQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPHPGPLLGAPAPPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSARVYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRVCPRPRGATATCSSDHQACCIPKPLPLCCKCPPPLLLGQFCSNSSSIRRTAPTAALPPRARCWAGTCRPRRRC
What are the official names of this protein?
Forkhead box protein D4-like 4, FOXD4-like 4, Forkhead box protein D4-like 2, Forkhead box protein D4B, Myeloid factor-gamma.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRC_GEOTN
Sequence: MAMWLKNGMSFNENGQLVRTHIKIEHGNIAAIHHEQLFEANGEDVIDVGGKLIAPGLIDVHVHLREPGGEAKETIETGTLAAAKGGFTTVAAMPNTNPVPDRKEQMEWLARRIQETAHVRVLPYASITLGQKGEELTDFAALKEAGAFAFTDDGVGVQSAGMMFEAMKRAAALDMAIVAHCEDDTLKNGGAVHDGDFARRYGIAGIPSVCEAVHIARDVLLAEATGCHYHVCHISTKESVRVVRDAKRAGICVTAEVTPHHLLLCDEDIPRLDANYKMNPPLRSRADREALIEGLLDGTIDFIATDHAPHTAAEKAKGMEAAPFGIVGLETAFPLLYTHFVKKNVFTLKQLVDWLTIKPAQCFGLQTGRLEVGAPADITVIDLETEEPIDPETFASKGNNTPFAGWRCQGWPVMTFVGGTLVWEKGRA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: QUEF_MANSM
Sequence: MDYKDNSLKTLKLGQKTDYIANYDRTLLQPVPRALNRDGLGITKQQPFSVGADIWTAYEISWLNIKGLPQVAIADVEIDYRSTNLIESKSFKLYLNSFNQTKFSDMSEVQRTISEDLSICAEGNVRVQLHSLSNYSHERIADFAGECLDELDIEISDYGFNAEILQNCTALSTEIVEETLVSHLLKSNCLITSQPDWGSVQIHYQGKRIDHEKLLRYLVSFRQHNEFHEQCVERIYCDIMKYARPEKLTVYARYTRRGGLDINPFRSNFEAIPQNLRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_MYCGE
Sequence: MSRTVDLKNFRNFGIMAHIDAGKTTTSERILFHSGRIHKIGETHDGESVMDWMEQEKERGITITSAATSVSWKNCSLNLIDTPGHVDFTVEVERSLRVLDGAIAVLDAQMGVEPQTETVWRQASRYEVPRVIFVNKMDKTGANFERSVLSIQQRLGVKAVPIQFPIGAENDFNGIIDIITKKAYFFDGNKEENAIEKPIPEQYVDQVEKLYNNLVEEVASLDDQLMADYLDGKPIEIDAIKNAIRNGVIHCKFFPVLCGSAFKNKGIKLLLDAVVDFLPSPVDVPPAKAIDANNKEISIKASDDANFIGLAFKVATDPFVGRLTFIRVYAGVLKSGSYVKNVRKNKKERVSRLVKMHAQNRNEIDEIRAGDICAVIGLKDTTTGETLTDDKLDVQLEAMQFAEPVISLAVEPKTKADQEKMSIALSKLAEEDPTFKTFSDPETGQTIIAGMGELHLDILVDRMKREFKVEVNIGAPQVSFRETFKSTSEVEGKYIKQSGGRGQYGHVKIRFEPNKDKGFEFVDKIVGGRIPREYIKPVQTGLENAMNSGPLAGYPMIDIKATLFDGSFHEVDSSEMAFKIAASLALKEAGKQCNPVLLEPIMAIEVTVPEQYFGDTMGDISSRRGIIEGTEQRDNVQLIKAKVPLKEMFGYATDLRSFSQGRGNYVMQFSHYAETPKSVVNEIIANKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT1_YEAST
Sequence: MNQSISSLIKLKFLQSHSNDKNGNKKGGSNVSTGIDKLRESESYRSPFLQLAEIQEHTNNDDDKLDVKECEPTKKHSKLSRIRRKMGRLDLNFRSANEKGSEDDEILVAQHLRNGQDPEEMPFKSENNIDSIEKVPKPDGERVTLTSSGSDNVKRNSKHAPFIPVKPALEKFPSSNRLSRDYRKSQEPTLFNGDRLVPTLPTVSRISTSSSVGSSTAASRYFNPSKRAVVASSSSSSSSIKFNSLHAIPLDATPQIELAKQQDEISKRRFGRRRSRTVDVFDYINKNNTAKNKPPLSPSSFIRTIDEKNTNSLMQDPMGSRGPLLPDDANIISNDTDGAEASHPDHQVLSRSRSQSTSFVQGKGGKRKSIEDEGYHNKLGLPHGSGPTSVYNNKSNANSTITGMSRRSSSIVNALSSFVNLRSSSLSSSRQQHLQQQQQLQQKLDVSLEDLPPVPAPEFSDSCKDFLIKLAPYGKFIGIILTEKDDEFKKNCLNYLLTNCFEFKNDPLDIALRKLLMFLELPKETQQIDRLIMAFSFAYYKAQKSYSKKKGIECPWSNADQVYFIAFSLLMLHTDYFNPNNKSKMTKHDFVDLVHNDKYSGGNEIPMAVLTYFYENVTAKESPKFNYFLMSPMALDDSILDKDAFDTNFAITLSSNSMYSPIDMIKRGSIIPKEASLSPIFYPLTNSISASGIAPSTAASCPPSTSGTINGANLGTANSNSNRPASNSISSYFSYNPSSSSSGNATLVQDDINVYSHIINDTLNEVNLFPEVSKYWNKNALKANLLRNEEHKYEKYYSIMNDTKGGYLRFHKSQLNKLNLPNFEILNDNSRSGCKNSDYKYCKILQMGAIMNLGMPSRKFSIVNSAKIHWKKEFAILTSLGLLICDKMDWINPQMMKDPKSGTTNYIIDFKSGFSFVPGSTIDVYNGLFADRERDSLGKSHFASLVLAYTEHHSTGSHTSNTTAASSSAKHNEGVFEPSSDEEDSITNSTDGTSSVSNGESDNDSVSSSDNQLSSNDSNEDYHSIKDEYPIFEDENADCLLYLHTCHRNFIWKCANKYERDNWIDSINLFSAYDGCYVEIGSIANTICNKRKLTILQRMERLRSIKSAKWEKLKKFESTLMLMGKCVPISTKTKTDMINRIRQLAVRMDWLIYEIKRSELFVSIIKEVTRKQAEKNILEHGKGEEEGQGNNDDSDGIDDIEESFLFNENSLQVCVSDSSYDEYSNE
What is the function of this protein?
Guanine nucleotide exchange factor for Arf GTPases, stimulating the nucleotide exchange from the GDP-bound to the GTP-bound form.  Catalyzes both the GDP release by and the GTP binding to ARF2.  Has no exchange activity on Rab GTPases.  Involved in vesicular transport.
What are the official names of this protein?
Arf guanine nucleotide exchange factor SYT1, Arf-GEF SYT1, Suppressor of YPT3 protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGN_MACFA
Sequence: MSSIKIECVLPENCRCGESPVWEEASDSLLFVDIPAKKLCRWDSLTKQVQRVTMDAPVSSVALRQSGGYVATIGTKFCALNWEEQSAVVLATVDNDKKNNRFNDGKVDPAGRYFAGTMAEETAPAVLERHQGSLYSLFPDHHVKKYFDQVDISNGLDWSLDHKIFYYIDSLSYSVDAFDYDLQTGQISNRRSVYKLEKEEQIPDGMCIDAEGKLWVACYNGGRVIRLDPVTGKRLQTVKLPVDKTTSCCFGGKNYSEMYVTCARDGMDPEGLLRQPEAGGIFKITGLGVKGIAPYSYAG
What is the function of this protein?
Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone.  Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro).  Calcium-binding protein.  Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity).
What are the official names of this protein?
Regucalcin, RC, Gluconolactonase, GNL, Senescence marker protein 30, SMP-30.
What is the protein family that this protein belongs to?
Belongs to the SMP-30/CGR1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_CORGB
Sequence: MTTSSEQPRTGYKRVMLKLGGEMFGGGKVGVDPDVVDNVARQIAEVAKTGAEIAVVIGGGNFFRGAELQQRGMDRARSDYMGMLGTVMNCLALQDFLGQHGVECRVQTAINMAQVAEPYLPLRAERHLEKGRVVIFGAGMGMPYFSTDTTAAQRALEIGCDVLLMAKAVDGVYSDDPRTNPDAELFTEITPKEVIEKGLKVADATAFSLCMDNKMPILVFNLLTEGNIARAISGERIGTLVES
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREF_HAEIN
Sequence: MAQTLNRSLTDLGALLHLVDPTLPIGGFNHSNGLETFVQQRVVESKATLEEYVQTQLLQNWIYNDGAYLSLAFDAMCEGNFDRLCELDWQLSATKVARESREGSFKLGVRLLKIFIRYETHTLLTAYQQAIAEKRVQGYFPIVFAMVAQAMGLSKADTLYAFYYNAAVGVITNGVKLIPLSQMDGQDILFDLRGSLVQAVELSLDPDEEWLGAATLANDIRAMQHEVLYTRLYMS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXM11_MACGS
Sequence: MKAPATIVILIMSLISVLWATADTEDGNLLFPIEDFIRKFDEYPVQPKERSCKLTFWRCKKDKECCGWNICTGLCIPPGKK
What is the function of this protein?
Blocks voltage-gated sodium channels (Nav) (By similarity).  Intracranial injection into mice causes lacrimation, slow breathing and death.  Intrathorax injection into crickets causes death.
What are the official names of this protein?
U12-hexatoxin-Mg1a, U12-HXTX-Mg1a, Neurotoxin magi-11, Peptide toxin 5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 15 family. 01 (magi-5) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LIPP_MOUSE
Sequence: MLMLWTFAVLLGAVAGREVCFDKLGCFSDDAPWSGTLDRPLKALPWSPAQINTRFLLYTNENPDNYQLITSDASNIRNSNFRTNRKTRIIIHGFIDKGEENWLSDMCKNMFRVESVNCICVDWKGGSRTTYTQATQNVRVVGAEVALLVNVLQSDLGYSLNNVHLIGHSLGSHIAGEAGKRTFGAIGRITGLDPAEPYFQGTPEEVRLDPTDAQFVDAIHTDAGPIIPNLGFGMSQTVGHLDFFPNGGIEMPGCQKNILSQIVDIDGIWEGTRNFAACNHLRSYKFYTDSIVNPTGFAGFSCSSYSLFTANKCFPCGSGGCPQMGHYADRYPGKTSRLYQTFYLNTGDKSNFARWRYQVTVTLSGQKVTGHILVSLFGNGGNSKQYEVFKGSLQPGTSHVNEFDSDVDVGDLQKVKFIWYNNVINPTLPKVGASRITVERNDGRVFNFCSQETVREDVLLTLSPC
What is the function of this protein?
Plays an important role in fat metabolism.  It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones.
What are the official names of this protein?
Pancreatic triacylglycerol lipase, PL, PTL, Pancreatic lipase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RGAP3_ARATH
Sequence: MTNFSRSKSTGTIGFPEFKPTRPGPDKYENIHNDDDEYEEGHSTTSTDYYDASTPLSSHASRSGNGSGSGQLTVVDLLAAVLRKSLVMSCAMERGEDDVVASMDIGWPTEVKHVSHVTFDRFNGFLGLPSELEPEVPPRAPSASVSVFGVSAKSMQCSYDDRGNSVPTILLRMQKRLYTEGGLKAEGIFRINPDNGKEEHVRRQLNCGVVPRGIDVHCLAGLIKAWFRELPTGVLDVLTPEQVMRCNTEEDCSRLVILLPPVESAILDWAIGLMADVVEHEQFNKMNARNVAMVFAPNMTQMADPLTALIHAVQVMNFLKTLILMNLKERENADAKARWLKKQTSDPSEEWESQHSEILSPEKPNNNNPKFLRVATLCRLEADNEEEFWNIKKRNDHEGVLDTSSGNGNIGPVQRLCKHPLFQLSKSTKKAFVSNRDEGRKGREAWSSRLSSLPW
What is the function of this protein?
Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state.  Involved in secondary wall pattern formation.  In association with ROPGEF4, mediates local activation of ARAC10/ROP11 to initiate the distinct pattern of secondary cell walls in xylem cells.
What are the official names of this protein?
Rho GTPase-activating protein 3, Rho-type GTPase-activating protein 3.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Localized at plasma membrane in the secondary wall pits.