PharMolix/UniProtQA huggingface dataset:
Protein: DUTP_ASFB7
Sequence: MATNFFIQPITQEAEAYYPPSVITNKRKDLGVDVYCCSDLVLQPGLNIVRLHIKVACEHMGKKCGFKIMARSSMCTHERLLILANGIGLIDPGYVGELMLKIINLGDTPVQIWAKECLVQLVAQGDHVPDHINILKRNQIFPLFAPTPRGEGRFGSTGEAGIMRT
What is the function of this protein?
The viral dUTPase may play a role in lowering the dUTP concentration in natural infections to minimize misincorporation of deoxyuridine into the viral DNA and ensure the fidelity of genome replication.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Found in association with viral nucleoid.
Protein: 3608L_ASFB7
Sequence: MLSLQTLAKKAVAKQSVPEEYHYILKYCGLWWQNKPISLCHYCNYVILSSTPFKGELLHLDVALIMAIKENNYDVIRLFTEWGANIYYGLTCARTEQTQELCRKLGAKDGLNNKEIFAGLMRHKTSNNIILCHEIFDKNPMLEALNVQEMGEEIHRELKLFIFYILDNVPMNIFVKYWYAIAVKYKLKRAIFFFYQTYGHLSMWRLMCAIYFNNVFDLHEIYEQKIVHMDIDKMMQLACMQDYNFLTIYYCFVLGADIDQAITVTQWHYHTNNLYFCKDLKDLKQNTLTARPLLLPNITDPKKIYTMLKNYLPTSSNSL
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-8L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: UP02_PINHA
Sequence: DVSLPAEGFR
What are the official names of this protein?
Unknown protein 2.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: EX7L_STRP8
Sequence: MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQYFSLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDGIGALALQFEQLKKKLTAEGYFEQKHKQPLPQFVSKIGVITSPSGAVIRDIITTVSRRFPGVEILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVVQAIFESQLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDLMSWIVERQNRSYQACLRRIKQRQEWVDKLSQSVIFRQPERLYDAYLQKIDRLSMTLMNTMKDRLSSAKENKVQLDHALANSQLQTKIERYQDRVATAKRLLMANMARQYDSQLARFEKAQDALLSLDVSRIIARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVKDVKNENI
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_CHRVO
Sequence: MPQYRSRTSTAGRNMAGARALWRATGMTDADFGKPIIAIANSFTQFVPGHVHLQNMGQLVAREIEKAGGVAKEFNTIAIDDGIAMGHGGMLYSLPSRDLIADSVEYMVNAHCADALVCISNCDKITPGMLMAAMRLNIPVVFVSGGPMEAGKVQWGNEVRKLDLVDAMVEAANSAVSDADVDRVERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSLVATHADRKELFLKAGRLIVELAKRHYEGEDYSILPRGIATKQAFENAMSLDVAMGGSTNTVLHLLAAASEAGVDFKMADIDRISRGVPCLSKVAPATQKYHMEDVHRAGGVIGILAELDRAGLIHRDVATVHSPSLGAAIEQWDVMRHGEGSEPHRLFRAAPGGVATTIAFSQSMRYPTLDDDRADGCIRDQAHAYSQDGGLAVLYGNIAERGCIVKTAGVDESILKFTGRARIFESQDAAVEGILADQIVAGDIVIIRYEGPKGGPGMQEMLYPTSYLKSKGLGKACALLTDGRFSGGTSGLSIGHASPEAAEGGAIGLAQEGDTVEIDIPNRRIHLAVSDEELAKRRAAMEAKGRDAWKPLGRERVVSPALRAYAAMTTSADTGAVRDVSQVERK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: LACA_STRS7
Sequence: MAIILGADAHGNELKEVLKGFLQQEGFDVTDVTDIDKDFIDNTLAVAQAVNDKDTNLGIMVDAYGAGPFMVATKLKGMIAAEVSDERSAYMTRGHNNARMMTMGAEIVGQELAKNIAKGFVTGHYDGGRHQIRVDMLNKMA
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: RNP1_HALS3
Sequence: MTTITPESLPRHELLGLHARVAADTDQSRVGIAGRVVDETMQTVVLRTASGVAQVPKKGATFEFRLTDEAAAPDNGVGTAFKPAGGETRQTTGESVAYVTVDGGRLLSRPERRSENGVDSKWR
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 1, RNase P component 1, Rpp29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AC53_NPVAC
Sequence: MFCTFCLKDRNYYMFKLFKDYWPTCTTECQICLEKIDDNGGIVAMPDTGMLNLEKMFHEQCIQRWRREHTRDPFNRVIKYYFNFPPKTLEECNVMLRETKGSIGDHEIDRVYKRVYQRVTQEDALDIELDFRHFFKMQS
What is the function of this protein?
Plays a role in nucleocapsid assembly.
What are the official names of this protein?
Protein AC53.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: CH601_MYCTO
Sequence: MSKLIEYDETARRAMEVGMDKLADTVRVTLGPRGRHVVLAKAFGGPTVTNDGVTVAREIELEDPFEDLGAQLVKSVATKTNDVAGDGTTTATILAQALIKGGLRLVAAGVNPIALGVGIGKAADAVSEALLASATPVSGKTGIAQVATVSSRDEQIGDLVGEAMSKVGHDGVVSVEESSTLGTELEFTEGIGFDKGFLSAYFVTDFDNQQAVLEDALILLHQDKISSLPDLLPLLEKVAGTGKPLLIVAEDVEGEALATLVVNAIRKTLKAVAVKGPYFGDRRKAFLEDLAVVTGGQVVNPDAGMVLREVGLEVLGSARRVVVSKDDTVIVDGGGTAEAVANRAKHLRAEIDKSDSDWDREKLGERLAKLAGGVAVIKVGAATETALKERKESVEDAVAAAKAAVEEGIVPGGGASLIHQARKALTELRASLTGDEVLGVDVFSEALAAPLFWIAANAGLDGSVVVNKVSELPAGHGLNVNTLSYGDLAADGVIDPVKVTRSAVLNASSVARMVLTTETVVVDKPAKAEDHDHHHGHAH
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_YERPP
Sequence: MVRFESTDSLMLARQLPNKTVALILAGGRGSRLKDLTATRAKPAVHFGGKFRIIDFALSNCLNSGVRRIGVITQYQSHTLVQHIQRGWSFLNEEMNEFVDLLPAQQRLSTEQWYKGTADAVCQNLDIIRRYDAEYIVILAGDHIYKMDYSRMLLDHVEKGAECTVACIPVPISEGSEFGIMEVTADYQITAFYEKPANPPPIPGDPSNALASMGIYIFNADYLFKLLEEDNNTPGSSHDFGKDIIPQLTARKVVWAHPFDLSCVTSNAELPPYWRDVGTLDAYWRANLDLASVTPELDMYDRAWPIRTHMEPLPPAKFVQDRSGSHGMTMNSLVSGGCIVSGSVVVHSVLFPRVRVNSFCTIDSSLLLPDVHVGRSCRLRRCIIDRACHIPEGMVIGENADEDSARFYRSEGGGGVSDSGYAGKVRGKIEPLGFLFVRLDLLIRLSLLIRLNLFIRMNLLIILTLFFKLASIQASH
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: CSPL2_MAIZE
Sequence: MDLERGDKKPPPPPPPAPRTAAATTTTTTTPACSGKKRPPLRDSLVALQPVLLRAAAALAAAAAAAVMALDAQSYTAVVAIVGTRPLTQTFTAKFSDTPAFVYFVIANAIAAAYNLLVLLVRRRRRTTAGLVVRMLDMVVMALLATGAAAAASMAELGRNGNARARWNPVCDRFGSFCRRGGAALAASFVGVALMLALNLLSAASGAGC
What are the official names of this protein?
CASP-like protein 1B1, ZmCASPL1B1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZMAT4_MOUSE
Sequence: MKSSDIDQDLFTDSYCKVCSAQLISESQRVAHYESRKHASKVRLYYMLHPRDGGCPAKRLRAENGSDADMVDKNKCCTLCNMSFTSAVVADSHYQGKIHAKRLKLLLGEKPPLKTTAAPLSSLKAPRVDTAPVVASPYQRRDSDRYCGLCAAWFNNPLMAQQHYEGKKHKKNAARVALLEQLGTSLDLGELRGLRRTYRCTTCSVSLNSIEQYHAHLQGSKHQTNLKNK
What are the official names of this protein?
Zinc finger matrin-type protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASSY_PSYWF
Sequence: MSIENKDNINKIVLAYSGGLDTSIIAKWLQDTYDAEVITFTADIGQGEEVEPARAKAEAMGIKHIHIEDLRAEFARDYVFPMFRANAIYEGEYLLGTSIARPLIAKRLVEIAKEHNADAISHGATGKGNDQVRFELGAIALAPDVKTIAPWREWDLSSRESLMAYAKEHNIPIDFAANKKKSPYSMDANLLHISYEGDILEDPYAEAEDDMWRWSVSPEQAPDTPEYLELEYEKGDIVAINGEKLEPYEVMIKLNELGGKHGIGRLDIVENRYVGMKSRGCYETPAGTIMLKAHRGMESLTLDREAAHLKDELMPRYAKIIYNGYWFSPERQMLQALIDKSQEYVTGTVRVKLYKGNVSVVGRKSPYSLFDEKIATFEDDAGAYDQKDAEGFIRLNGLRLSIEASRGRDLS
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_CLOBB
Sequence: MGQKVHPHGLRVGVIKGWDAKWYANKKDFADNLVEDNQIRKFVKKELFSAGISKIEIERAAKRVKLNIYTAKPGVVIGKGGSGIESLKKKLTNYISGKNILINIVEVKSVEAEAQLMAENIAAQLEKRISFRRAMKQTMQRAMRHGIKGVKTSCSGRLGGAEIARTEHYHEGTIPLQTLRADIDYGFAEANTTYGKIGVKVWVYKGEVLPTKKVEKEEANA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GMHD_CAMJE
Sequence: MSKKVLITGGAGYIGSVLTPILLEKGYEVCVIDNLMFDQISLLSCFHNKNFTFINGDAMDENLIRQEVAKADIIIPLAALVGAPLCKRNPKLAKMINYEAVKMISDFASPSQIFIYPNTNSGYGIGEKDAMCTEESPLRPISEYGIDKVHAEQYLLDKGNCVTFRLATVFGISPRMRLDLLVNDFTYRAYRDKFIVLFEEHFRRNYIHVRDVVKGFIHGIENYDKMKGQAYNMGLSSANLTKRQLAETIKKYIPDFYIHSANIGEDPDKRDYLVSNTKLEATGWKPDNTLEDGIKELLRAFKMMKVNRFANFN
What is the function of this protein?
NAD-dependent dehydrogenase involved in the biosynthesis of heptose moieties with a hydroxyl group at C6 found on the capsular polysaccharide (CPS) of C. jejuni.  Catalyzes the initial oxidation of C4 of the GDP-D-glycero-alpha-D-manno-heptose to form GDP-D-glycero-4-keto-alpha-D-lyxo-heptose in the presence of alpha-ketoglutarate required to recycle the NADH nucleotide.
What are the official names of this protein?
GDP-D-glycero-alpha-D-manno-heptose dehydrogenase.
Protein: AGRG1_HUMAN
Sequence: MTPQSLLQTTLFLLSLLFLVQGAHGRGHREDFRFCSQRNQTHRSSLHYKPTPDLRISIENSEEALTVHAPFPAAHPASRSFPDPRGLYHFCLYWNRHAGRLHLLYGKRDFLLSDKASSLLCFQHQEESLAQGPPLLATSVTSWWSPQNISLPSAASFTFSFHSPPHTAAHNASVDMCELKRDLQLLSQFLKHPQKASRRPSAAPASQQLQSLESKLTSVRFMGDMVSFEEDRINATVWKLQPTAGLQDLHIHSRQEEEQSEIMEYSVLLPRTLFQRTKGRSGEAEKRLLLVDFSSQALFQDKNSSQVLGEKVLGIVVQNTKVANLTEPVVLTFQHQLQPKNVTLQCVFWVEDPTLSSPGHWSSAGCETVRRETQTSCFCNHLTYFAVLMVSSVEVDAVHKHYLSLLSYVGCVVSALACLVTIAAYLCSRVPLPCRRKPRDYTIKVHMNLLLAVFLLDTSFLLSEPVALTGSEAGCRASAIFLHFSLLTCLSWMGLEGYNLYRLVVEVFGTYVPGYLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHRTPEGVIYPSMCWIRDSLVSYITNLGLFSLVFLFNMAMLATMVVQILRLRPHTQKWSHVLTLLGLSLVLGLPWALIFFSFASGTFQLVVLYLFSIITSFQGFLIFIWYWSMRLQARGGPSPLKSNSDSARLPISSGSTSSSRI
What is the function of this protein?
Plays a critical role in cancer progression by activating VEGFA production and angiogenesis through a signaling pathway mediated by PRKCA (PubMed:21724588).
What are the official names of this protein?
Adhesion G-protein coupled receptor G1, G-protein coupled receptor 56, Protein TM7XN1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Protein: CINA_STRA1
Sequence: MRAEIIAVGTEILTGQIVNTNAQFLSEKMAELGIDIYFQTAVGDNEERLLSLLDIASQRSQLVILCGGLGPTEDDLTKQTLAKFLGKSLTVDLLASQKLDRFFASRPQFARTPNNERQAQLVEGSIPLQNLTGLAVGGIVTSKGVQYMVLPGPPSELNPMVMEQVVPILSNNGTKLYSRVLRFFGIGESQLVTILEDIIKNQTDPTIAPYAKVGEVTLRLSTKAENQDEADFKLDSLEKEILALKTLDNRKLKDLLYGYGDNNSMARTVLELLKVQNKTITAAESLTAGLFQSQLAEFSGASQVFNGGFTTYSMEAKSQLLGIPKKKLQEYGVISHFTAEAMAQQARQLLKADFGIGLTGVAGPDELEGYPAGTVFIGIATPEGVSSIKVSIGGKSRSDVRHISTLHAFDLVRRALLKI
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: RUVA_PROMP
Sequence: MISWIKGELVSSWQANNKFYILVNCQGLGYEIQTLESVFFDINSNKISEKEIILWLKHIKKEDSDMLFGFSTKDQRDFFIQILNIKGIGSQIGMSLLNKFSLNQLITAISNNDKKSISTVQGIGQKMTERIILELKSKVINKEIEKENLNINNFLEKNKDLDSIFKDIDLTLQSLNYSKKEIKNLFPKLINNIKNSSLEKESISFENLLKEAMNYLDHK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SHE10_ZYGRC
Sequence: MKILTKFFLLLVVTTCSLHYYCQIGQCSTQLQRVCHYTTPSVWDELLVEKNEFYREQLNPKVKVLKSHISQINSHYQDKVLPKLVDLGNRFYFDIVSPRIDNVCEFWEEFELKPYRERSLNQIRKVRQRIWFYYSVYLKPNLTKLDNQYALSDKYGKVHNKIAPFVAEIAQNFQNVYHQAAAKVHPHWENLRRTVNAKWEPISSSLWQRCRTNEICFKTNAQLKNIWKNLKLGCDYLSIYVHDALSPYSDGLESNVRATKAKSKSKPRVNASASARGNARAGAKAGAKAGTSEISASATADPTTSASATVTAGFEDDYDDEEPLYTSTSTIMLTVTMSTDQNELSPSQNTANAELGISEQDAIKDEFEAWFKVVDQKSSGVVKTFNKEVNKYLHHRVQQLDSIFQNKTKTVSEVLQNRYKNLNRAIQDINCTCETDTGAGNQTCFDSTGTTQLSEYITRSKMRELFAEAHSTLDQSMLQLKQDLEPIAQEVESRVSLIREEMVEVYEEWGDAMVSEWSKRLAYIDVVAGHLDDNGASTDEESSENWRKFLNLKKQVIKARDELAEHPADLHEIKQFVKKVHYLIEVLAKEAGEYLYILRARANLAFQAREQESKQREDSPRMDRDSTQNVENSNTTTASAEKSGKKAKKVKRVAQNGTNSTEKFSAGPDSSSKEPSMETTVQNNVTLQI
What is the function of this protein?
Involved in spore wall assembly.  May be a component of the mitochondrial RNase MRP (MtMRP), a ribonucleoprotein endoribonuclease involved in the cleaving RNA transcripts to generate primers for DNA replication in mitochondria.
What are the official names of this protein?
Outer spore wall assembly protein SHE10, Sensitivity to high expression protein 10.
What is the protein family that this protein belongs to?
Belongs to the SHE10 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: OL151_MOUSE
Sequence: MTAENQSTVTEFILGGLTNRPELQLPLFLLFLGIYVVTMVGNLGMITLIGLNSQLHTPMYFFLSNLSLVDLCYSSVITPKMLINFVSQRNLISYVGCMSQLYFFLVFVIAECYMLTVMAYDRYVAICQPLLYNIIMSPALCSLLVAFVYAVGLIGSAIETGLMLKLNYCEDLISHYFCDILPLMKLSCSSTYDVEMAVFFLAGFDIIVTSLTVLISYAFILSSILRISSNEGRSKAFSTCSSHFAAVGLFYGSTAFMYLKPSTASSLAQENVASVFYTTVIPMFNPLIYSLRNKEVKTALDKTLRRKVF
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 151, Odorant receptor M71, Olfactory receptor 171-2, Olfactory receptor 7H.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PFES_PSEAE
Sequence: MRRHPLLWKLALLQVGFCLLLTWLIYTWGLSVERSTYFLAPADRHYLADYARQAEDAWRREGAAGAERFRKELSAKEDTWVALVGPHLESLGSTPLSAEESSHLTFMRKLDWPMSRRLQDELPYVSIEFPGHPEQGRLVIQLPERLLPGGLTPWTHLVTHGIVPTLLAALLGLLLYRHLVVPLNRLRDRADALRADELESTPLAAPLAARRDELGELAQALEHMAERLRLSLAQQRLLLRTLSHELRTPLARLRIAHDSELPPEQLRQRLDREIGDMQRLLEDTLDLAWMDTERPQLPTEPVLALSVWEALRDDACFESGWDPARLPCRLGVDCRVEVHLDSLAQAMENLLRNAIRHSPEDGTVSLDGEREGDFWHLRLQDQGPGVAEDQLERIFLPYQRLDDSAGEGFGLGLAIARRAIELQGGRLWASNGKPGLCLHLWLPAAA
What is the function of this protein?
Member of the two-component regulatory system PfeR/PfeS.  May activate PfeR by phosphorylation.
What are the official names of this protein?
Sensor protein PfeS.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QCRA_GEOTD
Sequence: MSDNKHRVTRRQFLNYTLTGVGGFMAAGMLMPMLRFAFDPILRETAGTDMVAVADVKEITTEPKRFDFKVKVKDAWYESEEPRSAWVYKDEKGDIIALSPVCKHLGCTVDWNTDKNNPNHFFCPCHYGLYTKDGTNVPGTPPTAPLDRYEFEVKDGKLYLGKAKPRGEA
What is the function of this protein?
Component of the menaquinol-cytochrome c reductase complex.  The Rieske protein is a high potential 2Fe-2S protein.
What are the official names of this protein?
Menaquinol-cytochrome c reductase iron-sulfur subunit, Rieske iron-sulfur protein.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
Protein: RPOE_BACC7
Sequence: MDFKQYSPEELKECSMIEVVHSVLGDKKQATTFNELVQEIAQVLGLSQEQVNAKIAQFYTDLNIDGRFINLGENRWGLRSWYPYEQIDEEILPQPKPKKKRKVEEDGFDDYIEEDEDDFDDVDGNEDEDDDVEDLDKVLEDEDGDDDDLDDLDDDEDDFAEEELEYDETEEEEEEEL
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: YJZH_BACSU
Sequence: MKEYEFVRVELSTMRRRPKEDYQQIIHDYAKRGWRFVQIFAPSIDGYGAAAYFEIIFERDAEKA
What are the official names of this protein?
Uncharacterized protein YjzH.
Protein: RPPH_ECOBW
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQENTPKPQNASAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: SCMC1_BOVIN
Sequence: MLRWLRGFVLPTAACQDVEPPTRYETLFQKLDRNGDGVVDISELQEGLKSLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQILGLTISEQQAELILQSIDADGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGVAGAVSRTSTAPLDRLKVMMQVHGSKSAKMNIYGGFQQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFVSGSMAGATAQTFIYPMEVLKTRLAVGKTGQYSGMFDCAKKILKYEGMGAFYKGYVPNLLGIIPYAGIDLAVYELLKSHWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMIEKSPQLNMVGLFRRILSKEGLPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK
What is the function of this protein?
Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane.  Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter.  By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways.  In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides.  May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates.
What are the official names of this protein?
Mitochondrial adenyl nucleotide antiporter SLC25A24, Small calcium-binding mitochondrial carrier protein 1, SCaMC-1, Solute carrier family 25 member 24.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PYRB_PICTO
Sequence: MLKNNSVISINDLSDEDLNLIFNTADSMAGNLKNGSQIKTMSGRIMATLFFEPSTRTRLSFESAMQRLGGSVISMADSKSSSTAKGETLADTTRMVSSYSDIIVVRHPLEGAARLVQKFSSRPVINAGDGSGEHPTQTLVDLYTIKKSFGDINNLEISIIGDLRYGRTVHSLLLALSRYNVRINLVSPDLLRLPGHVMSRLKNIKINEYNDLNNVIESSDVFYVTRIQRERFTDKNDYNKVIGTYGITEKDTEKMKENAIIMHPLPRVDEISSSVDNTKNAKYFIQAANGIPVRMALISLILGD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PURL_STAEQ
Sequence: MSKFIEPSNEEIKLEKLYQDMGLSDKEYDKVVEILGREPNFTEVGIFSVMWSEHCSYKHSKPFLKQFPTTGEHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELTVKQNQRLLKGVVSGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGIIDHDMVQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLDQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFNKHELDSAVIGEVTDTDRFVLTYDDEVYADIPVQPLADEAPVYILEGEEKEYNTSKNDYSNIDVHDTFIKLLQHPTIASKHHLYEQYDQQVGANTIIKPGLQASVVRVEGTQKAIASTIDGEARYVFNQPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMSEACKVLQTPVVSGNVSLYNETRGTSIFPTPVVGMVGLIEDVSYLKEFKPKAGDKIYLVGETRDDFGGSQLEKLLYGSVNHEFESIDLSDEVSKGKLIKQAIRNGIASHVQTVGKGGLLVTLAKISAHYDLGMQAQLDVTNAQLFSETQGRYIVVVKEGQTLDIDQAQEIGHLTHQQLFDISNSDVKMKENVSDIKQKWEGAIVQCLTTQD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_GEOKA
Sequence: MSFNHREIEQKWQDYWEKNKTFRTPDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILARMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIDNFRRQIKSLGFSYDWDREINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVINGRSERGGHPVIRKPMRQWMLKITAYADRLLEDLEELDWPESIKEMQRNWIGRSEGAEIEFAVHGHDETFTVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKPAVDAYLKEIQSKSDLERTDLAKEKTGVFTGAYAIHPVTGDRLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFHLPMKEVVAGGDIEKEPYTGDGEHINSEFLNGLNKQEAIDKMIAWLEEHGKGRKKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTMTPVPEEELPLVLPKTDEIRPSGTGESPLANIEEWVNVVDPKTGKKGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYARFWHKFLYDLGIVPTKEPFQKLFNQGMILGENNEKMSKSKGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLDRVWRLFVTENGELNPNIVDEPANDTLERIYHQTVKKVTEDYESLRFNTAISQLMVFINEAYKAEQMKKEYMEGFVKLLSPVCPHIGEELWQKLGHTDTIAYEPWPTYDETKLVEDVVEIVVQINGKVRSRLHVPVDLPKEALEERALADEKIKEQLEGKTVRKVIAVPGKLVNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_BLOPB
Sequence: MKIRPLHDRVIVKRKEVESKSAGGIVLTGSAAGKSTRGEVLAVGHGRVLENGGVKALDVRIGDTVIFNDGYGVKVEKIDNEEVLIMSESDILAIVEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.